Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionG protein-coupled receptor activity

GPR3 OR5M9 OR4C11 OR5G3 OR6K2 OR5D14 CYSLTR1 OR6C65 OR5M8 ACKR4 OR1J2 OR4K14 SORCS1 OR9A1P FZD1 OR51E2 OR52R1 OR6V1 OR4S1 CELSR3 OR51M1 OR52E6 OR52N5 OR52E4 RRH OR2D3 SORCS3 OR4F21 OR2Z1 OR7G3 OR4F6

2.53e-1588412531GO:0004930
GeneOntologyMolecularFunctionolfactory receptor activity

OR5M9 OR4C11 OR5G3 OR6K2 OR5D14 OR6C65 OR5M8 OR1J2 OR4K14 OR9A1P OR51E2 OR52R1 OR6V1 OR4S1 OR51M1 OR52E6 OR52N5 OR52E4 OR2D3 OR4F21 OR2Z1 OR7G3 OR4F6

2.71e-1543112523GO:0004984
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

GPR3 TRPV1 OR5M9 OR4C11 OR5G3 OR6K2 OR5D14 CYSLTR1 OR6C65 GRIN2A OR5M8 ACKR4 OR1J2 OR4K14 SORCS1 OR9A1P FZD1 OR51E2 OR52R1 OR6V1 OR4S1 CELSR3 LMBR1L OR51M1 OR52E6 OR52N5 PTCH2 OR52E4 RRH OR2D3 SORCS3 OR4F21 OR2Z1 OR7G3 OR4F6

2.49e-13135312535GO:0004888
GeneOntologyMolecularFunctiontransporter activity

LRRC8E GPM6A LRRC8C TRPV1 ABCA2 ATP6V0B SLC35D2 ATG2B ANO1 TCIRG1 ABCC5 SLC26A9 CACHD1 GRIN2A FLVCR2 SLC39A10 SLC1A2 SLC7A14 SEC61A2 KCND3 KCNH2 SCN1B SLC22A2 SCN3A NPC1L1 CYB561D1 SLC12A7 SEC61A1 DISP1

1.17e-09128912529GO:0005215
GeneOntologyMolecularFunctiontransmembrane transporter activity

LRRC8E GPM6A LRRC8C TRPV1 ABCA2 ATP6V0B SLC35D2 ANO1 TCIRG1 ABCC5 SLC26A9 CACHD1 GRIN2A FLVCR2 SLC39A10 SLC1A2 SLC7A14 SEC61A2 KCND3 KCNH2 SCN1B SLC22A2 SCN3A CYB561D1 SLC12A7 SEC61A1 DISP1

3.43e-09118012527GO:0022857
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

LRRC8E GPM6A LRRC8C TRPV1 ATP6V0B ANO1 TCIRG1 SLC26A9 CACHD1 GRIN2A SLC39A10 SLC1A2 KCND3 KCNH2 SCN1B SCN3A SLC12A7 SEC61A1

2.21e-0679312518GO:0015075
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

GPM6A TRPV1 ATP6V0B ANO1 TCIRG1 ABCC5 SLC26A9 CACHD1 GRIN2A SLC39A10 SLC1A2 KCND3 KCNH2 SCN1B SCN3A SLC12A7 SEC61A1

5.10e-0675812517GO:0015318
GeneOntologyMolecularFunctionchannel activity

LRRC8E GPM6A LRRC8C TRPV1 ANO1 SLC26A9 CACHD1 GRIN2A KCND3 KCNH2 SCN1B SCN3A SLC12A7 SEC61A1

5.38e-0652512514GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

LRRC8E GPM6A LRRC8C TRPV1 ANO1 SLC26A9 CACHD1 GRIN2A KCND3 KCNH2 SCN1B SCN3A SLC12A7 SEC61A1

5.49e-0652612514GO:0022803
GeneOntologyMolecularFunctionmonoatomic ion channel activity

LRRC8E GPM6A LRRC8C TRPV1 ANO1 SLC26A9 CACHD1 GRIN2A KCND3 KCNH2 SCN1B SCN3A SEC61A1

6.25e-0645912513GO:0005216
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

GPM6A TRPV1 ATP6V0B ANO1 TCIRG1 CACHD1 GRIN2A SLC39A10 SLC1A2 KCND3 KCNH2 SCN1B SCN3A SLC12A7 SEC61A1

1.76e-0566412515GO:0008324
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

GPM6A TRPV1 CACHD1 GRIN2A SLC39A10 SLC1A2 KCND3 KCNH2 SCN1B SCN3A SLC12A7 SEC61A1

3.61e-0546512512GO:0046873
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

GPM6A TRPV1 ATP6V0B TCIRG1 CACHD1 GRIN2A SLC39A10 SLC1A2 KCND3 KCNH2 SCN1B SCN3A SLC12A7 SEC61A1

3.88e-0562712514GO:0022890
GeneOntologyMolecularFunctionmonoatomic cation channel activity

GPM6A TRPV1 ANO1 CACHD1 GRIN2A KCND3 KCNH2 SCN1B SCN3A SEC61A1

6.06e-0534312510GO:0005261
GeneOntologyMolecularFunctionglycerol kinase activity

GK GK2

1.16e-0431252GO:0004370
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH3 DNAH12 DNAH6

1.82e-04181253GO:0008569
GeneOntologyMolecularFunctionactive transmembrane transporter activity

ABCA2 ATP6V0B SLC35D2 TCIRG1 ABCC5 SLC26A9 SLC39A10 SLC1A2 SLC22A2 CYB561D1 SLC12A7

2.07e-0447712511GO:0022804
GeneOntologyMolecularFunctionmonoatomic anion transmembrane transporter activity

LRRC8E LRRC8C ANO1 SLC26A9 SLC1A2 SLC12A7

3.79e-041511256GO:0008509
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLC35D2 ABCC5 SLC26A9 GRIN2A SLC39A10 SLC1A2 SLC7A14 SLC22A2

5.22e-042931258GO:0008514
GeneOntologyMolecularFunctionsulfur compound transmembrane transporter activity

ABCC5 SLC26A9 SLC1A2 SLC22A2

5.80e-04611254GO:1901682
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH3 DNAH12 DNAH6

7.00e-04281253GO:0051959
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity

TRPV1 ANO1 CACHD1 GRIN2A KCND3 KCNH2

1.01e-031821256GO:0005244
GeneOntologyMolecularFunctionvoltage-gated channel activity

TRPV1 ANO1 CACHD1 GRIN2A KCND3 KCNH2

1.07e-031841256GO:0022832
GeneOntologyMolecularFunctionodorant binding

OR5M9 OR5G3 OR6K2 OR5D14 OR5M8

1.23e-031271255GO:0005549
GeneOntologyMolecularFunctionmacromolecule transmembrane transporter activity

ABCC5 SEC61A2 SEC61A1

1.24e-03341253GO:0022884
GeneOntologyMolecularFunctioncalcium channel activity

GPM6A TRPV1 CACHD1 GRIN2A SEC61A1

1.32e-031291255GO:0005262
GeneOntologyMolecularFunctionheme transmembrane transporter activity

ABCC5 FLVCR2

1.36e-0391252GO:0015232
GeneOntologyMolecularFunctionvolume-sensitive anion channel activity

LRRC8E LRRC8C

1.36e-0391252GO:0005225
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNAH3 DNAH12 DNAH6

1.59e-03371253GO:0045505
GeneOntologyMolecularFunctionvoltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization

KCND3 KCNH2

2.46e-03121252GO:1902282
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

GPM6A TRPV1 CACHD1 GRIN2A SEC61A1

2.62e-031511255GO:0015085
GeneOntologyMolecularFunctionvoltage-gated monoatomic cation channel activity

TRPV1 CACHD1 GRIN2A KCND3 KCNH2

2.70e-031521255GO:0022843
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception

TRPV1 OR5M9 OR4C11 OR5G3 OR6K2 OR5D14 ANO1 OR6C65 GRIN2A OR5M8 OR1J2 OR4K14 OR9A1P OR51E2 OR52R1 OR6V1 OR4S1 OR51M1 OR52E6 OR52N5 OR52E4 OR2D3 OR4F21 OR2Z1 OR7G3 OR4F6

1.65e-1558212726GO:0050906
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception of smell

OR5M9 OR4C11 OR5G3 OR6K2 OR5D14 OR6C65 OR5M8 OR1J2 OR4K14 OR9A1P OR51E2 OR52R1 OR6V1 OR4S1 OR51M1 OR52E6 OR52N5 OR52E4 OR2D3 OR4F21 OR2Z1 OR7G3 OR4F6

2.07e-1543212723GO:0050911
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception

TRPV1 OR5M9 OR4C11 OR5G3 OR6K2 OR5D14 OR6C65 OR5M8 OR1J2 OR4K14 OR9A1P OR51E2 OR52R1 OR6V1 OR4S1 OR51M1 OR52E6 OR52N5 OR52E4 OR2D3 OR4F21 OR2Z1 OR7G3 OR4F6

2.43e-1548512724GO:0050907
GeneOntologyBiologicalProcesssensory perception of smell

OR5M9 OR4C11 OR5G3 OR6K2 OR5D14 OR6C65 OR5M8 OR1J2 OR4K14 OR9A1P OR51E2 OR52R1 OR6V1 OR4S1 OR51M1 OR52E6 OR52N5 OR52E4 OR2D3 OR4F21 OR2Z1 OR7G3 OR4F6

1.00e-1446512723GO:0007608
GeneOntologyBiologicalProcessdetection of chemical stimulus

TRPV1 OR5M9 OR4C11 OR5G3 OR6K2 OR5D14 OR6C65 OR5M8 OR1J2 OR4K14 OR9A1P OR51E2 OR52R1 OR6V1 OR4S1 OR51M1 OR52E6 OR52N5 OR52E4 OR2D3 OR4F21 OR2Z1 OR7G3 OR4F6

1.34e-1452412724GO:0009593
GeneOntologyBiologicalProcessdetection of stimulus

TRPV1 OR5M9 OR4C11 OR5G3 OR6K2 OR5D14 ANO1 OR6C65 GRIN2A OR5M8 OR1J2 OR4K14 OR9A1P OR51E2 OR52R1 OR6V1 OR4S1 OR51M1 OR52E6 OR52N5 OR52E4 RRH OR2D3 OR4F21 OR2Z1 OR7G3 OR4F6

3.31e-1472212727GO:0051606
GeneOntologyBiologicalProcesssensory perception of chemical stimulus

TRPV1 OR5M9 OR4C11 OR5G3 OR6K2 OR5D14 OR6C65 OR5M8 OR1J2 OR4K14 OR9A1P OR51E2 OR52R1 OR6V1 OR4S1 OR51M1 OR52E6 OR52N5 OR52E4 OR2D3 OR4F21 OR2Z1 OR7G3 OR4F6

3.43e-1454712724GO:0007606
GeneOntologyBiologicalProcesssensory perception

TRPV1 OR5M9 OR4C11 OR5G3 OR6K2 OR5D14 ANO1 OR6C65 GRIN2A OR5M8 OR1J2 OR4K14 OR9A1P OR51E2 OR52R1 OR6V1 OR4S1 OR51M1 OR52E6 OR52N5 RETREG1 OR52E4 RRH OR2D3 CLDN19 OR4F21 OR2Z1 OR7G3 OR4F6

1.06e-11107212729GO:0007600
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

GPR3 OR5M9 OR4C11 OR5G3 OR6K2 OR5D14 CYSLTR1 ANO1 OR6C65 OR5M8 ACKR4 OR1J2 OR4K14 SORCS1 OR9A1P FZD1 OR51E2 ADM OR52R1 OR6V1 OR4S1 CELSR3 OR51M1 OR52E6 OR52N5 OR52E4 RRH OR2D3 SORCS3 OR4F21 OR2Z1 OR7G3 OR4F6

1.09e-11139512733GO:0007186
GeneOntologyBiologicalProcesssulfur compound transport

LRRC8C ABCC5 SLC26A9 SLC1A2 SLC35F3 SLC22A2

2.97e-06651276GO:0072348
GeneOntologyBiologicalProcessimport across plasma membrane

LRRC8E LRRC8C TRPV1 SLC39A10 SLC1A2 KCND3 KCNH2 SLC22A2 SLC12A7

1.29e-052301279GO:0098739
GeneOntologyBiologicalProcessmonoatomic ion transport

LRRC8E GPM6A LRRC8C TRPV1 ATP6V0B CYSLTR1 ANO1 TCIRG1 ABCC5 SLC26A9 CACHD1 GRIN2A FLVCR2 SLC39A10 SLC1A2 KCND3 KCNH2 SCN1B SLC22A2 SCN3A SLC12A7 SEC61A1

3.20e-05137412722GO:0006811
GeneOntologyBiologicalProcesscyclic nucleotide transport

LRRC8E LRRC8C ABCC5

3.63e-05111273GO:0070729
GeneOntologyBiologicalProcessguanine nucleotide transport

LRRC8E LRRC8C ABCC5

3.63e-05111273GO:0001408
GeneOntologyBiologicalProcessmonoatomic anion transmembrane transport

LRRC8E LRRC8C ANO1 ABCC5 SLC26A9 SLC1A2 SLC12A7

4.57e-051531277GO:0098656
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

LRRC8E GPM6A LRRC8C TRPV1 ATP6V0B ANO1 TCIRG1 ABCC5 SLC26A9 CACHD1 GRIN2A SLC39A10 SLC1A2 KCND3 KCNH2 SCN1B SCN3A SLC12A7 SEC61A1

5.20e-05111512719GO:0034220
GeneOntologyBiologicalProcessdicarboxylic acid transport

LRRC8E LRRC8C TRPV1 ABCC5 SLC26A9 SLC1A2

9.97e-051201276GO:0006835
GeneOntologyBiologicalProcessglycerol-3-phosphate biosynthetic process

GK GK2

1.12e-0431272GO:0046167
GeneOntologyBiologicalProcessmonoatomic anion transport

LRRC8E LRRC8C ANO1 ABCC5 SLC26A9 SLC1A2 SLC12A7

1.41e-041831277GO:0006820
GeneOntologyBiologicalProcesscirculatory system process

TRPV1 ABCA2 PLOD3 CYSLTR1 ABCC5 SLC1A2 OR51E2 ADM KCND3 KCNH2 SCN1B SLC22A2 SCN3A OCLN

1.72e-0473312714GO:0003013
GeneOntologyBiologicalProcessresponse to pyrethroid

SCN1B SCN3A

2.24e-0441272GO:0046684
GeneOntologyBiologicalProcessmonoatomic cation transport

GPM6A TRPV1 ATP6V0B CYSLTR1 ANO1 TCIRG1 ABCC5 CACHD1 GRIN2A FLVCR2 SLC39A10 KCND3 KCNH2 SCN1B SLC22A2 SCN3A SLC12A7 SEC61A1

2.59e-04115712718GO:0006812
GeneOntologyBiologicalProcessaspartate transmembrane transport

LRRC8E LRRC8C SLC1A2

3.22e-04221273GO:0015810
GeneOntologyBiologicalProcessvitamin transport

ABCC5 SLC35F3 SLC22A2 NPC1L1

3.93e-04561274GO:0051180
GeneOntologyBiologicalProcessintracellular glucose homeostasis

VSNL1 HK1 ANO1 PTPRN AACS SLC12A7 VCAM1

4.09e-042181277GO:0001678
GeneOntologyBiologicalProcesslysosomal lumen acidification

ATP6V0B TMEM199 TCIRG1

4.20e-04241273GO:0007042
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

GPM6A TRPV1 ATP6V0B ANO1 TCIRG1 ABCC5 SLC26A9 CACHD1 GRIN2A SLC39A10 KCND3 KCNH2 SCN1B SCN3A SLC12A7 SEC61A1

5.18e-04101712716GO:0098660
GeneOntologyBiologicalProcesscarboxylic acid transmembrane transport

LRRC8E LRRC8C SLC35D2 ABCC5 SLC1A2 SLC22A2

5.22e-041631276GO:1905039
GeneOntologyBiologicalProcessglycerol catabolic process

GK GK2

5.55e-0461272GO:0019563
GeneOntologyBiologicalProcesscardiac muscle cell action potential involved in contraction

KCND3 KCNH2 SCN1B SCN3A

5.80e-04621274GO:0086002
GeneOntologyBiologicalProcessorganic acid transmembrane transport

LRRC8E LRRC8C SLC35D2 ABCC5 SLC1A2 SLC22A2

5.94e-041671276GO:1903825
GeneOntologyBiologicalProcessprotein catabolic process in the vacuole

TMEM199 TCIRG1 CD81

6.67e-04281273GO:0007039
GeneOntologyBiologicalProcesslabyrinthine layer morphogenesis

ADM SPINT2 VCAM1

6.67e-04281273GO:0060713
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

GPM6A TRPV1 ATP6V0B ANO1 TCIRG1 ABCC5 CACHD1 GRIN2A SLC39A10 KCND3 KCNH2 SCN1B SCN3A SLC12A7 SEC61A1

6.90e-0494212715GO:0098655
GeneOntologyBiologicalProcessC4-dicarboxylate transport

LRRC8E LRRC8C SLC1A2

7.41e-04291273GO:0015740
GeneOntologyBiologicalProcessalditol catabolic process

GK GK2

7.74e-0471272GO:0019405
GeneOntologyBiologicalProcessventricular cardiac muscle cell membrane repolarization

KCND3 KCNH2 SCN1B

8.20e-04301273GO:0099625
GeneOntologyCellularComponentmembrane protein complex

LRRC8E LRRC8C ABCA2 ATP6V0B TMEM199 ANO1 TCIRG1 CACHD1 GRIN2A ITGA7 PIGU SLC1A2 TSPAN33 SEC61A2 KCND3 KCNH2 SCN1B GYPE SCN3A TRBC2 TRBC1 SEC61A1 VCAM1 AP3S2

1.05e-05149812724GO:0098796
GeneOntologyCellularComponenttransmembrane transporter complex

LRRC8E LRRC8C ABCA2 ATP6V0B TMEM199 ANO1 TCIRG1 CACHD1 GRIN2A KCND3 KCNH2 SCN1B SCN3A

1.83e-0552312713GO:1902495
GeneOntologyCellularComponentinner dynein arm

DNAH3 DNAH12 DNAH6

2.55e-05101273GO:0036156
GeneOntologyCellularComponenttransporter complex

LRRC8E LRRC8C ABCA2 ATP6V0B TMEM199 ANO1 TCIRG1 CACHD1 GRIN2A KCND3 KCNH2 SCN1B SCN3A

3.10e-0555012713GO:1990351
GeneOntologyCellularComponentendoplasmic reticulum membrane

LRRC8E LRRC8C PLOD3 TMEM199 ATG2B SLC26A9 ERMP1 GRIN2A PIGG FLVCR2 SPPL2B PIGU SEC61A2 LMBR1L TMEM259 OR51M1 DHCR24 RETREG1 SEC61A1

2.99e-04129312719GO:0005789
GeneOntologyCellularComponentendoplasmic reticulum subcompartment

LRRC8E LRRC8C PLOD3 TMEM199 ATG2B SLC26A9 ERMP1 GRIN2A PIGG FLVCR2 SPPL2B PIGU SEC61A2 LMBR1L TMEM259 OR51M1 DHCR24 RETREG1 SEC61A1

3.17e-04129912719GO:0098827
GeneOntologyCellularComponentATPase dependent transmembrane transport complex

ABCA2 ATP6V0B TMEM199 TCIRG1

3.49e-04551274GO:0098533
GeneOntologyCellularComponentSec61 translocon complex

SEC61A2 SEC61A1

3.62e-0451272GO:0005784
GeneOntologyCellularComponentnuclear outer membrane-endoplasmic reticulum membrane network

LRRC8E LRRC8C PLOD3 TMEM199 ATG2B SLC26A9 ERMP1 GRIN2A PIGG FLVCR2 SPPL2B PIGU SEC61A2 LMBR1L TMEM259 OR51M1 DHCR24 RETREG1 SEC61A1

4.13e-04132712719GO:0042175
GeneOntologyCellularComponentaxonemal dynein complex

DNAH3 DNAH12 DNAH6

4.57e-04251273GO:0005858
GeneOntologyCellularComponentmonoatomic ion channel complex

LRRC8E LRRC8C ANO1 CACHD1 GRIN2A KCND3 KCNH2 SCN1B SCN3A

5.11e-043781279GO:0034702
GeneOntologyCellularComponentvacuolar proton-transporting V-type ATPase complex

ATP6V0B TMEM199 TCIRG1

5.14e-04261273GO:0016471
GeneOntologyCellularComponenttranslocon complex

SEC61A2 SEC61A1

5.41e-0461272GO:0071256
GeneOntologyCellularComponentproton-transporting V-type ATPase complex

ATP6V0B TMEM199 TCIRG1

7.13e-04291273GO:0033176
GeneOntologyCellularComponentapical plasma membrane

ANO1 TCIRG1 ABCC5 SLC26A9 SLC39A10 SLC22A2 NPC1L1 CD81 OCLN VCAM1

7.91e-0448712710GO:0016324
GeneOntologyCellularComponenttetraspanin-enriched microdomain

TSPAN33 CD81

1.60e-03101272GO:0097197
GeneOntologyCellularComponentvacuolar proton-transporting V-type ATPase, V0 domain

ATP6V0B TCIRG1

1.60e-03101272GO:0000220
GeneOntologyCellularComponentalpha-beta T cell receptor complex

TRBC2 TRBC1

2.32e-03121272GO:0042105
GeneOntologyCellularComponentproton-transporting V-type ATPase, V0 domain

ATP6V0B TCIRG1

2.32e-03121272GO:0033179
GeneOntologyCellularComponentcation-transporting ATPase complex

ATP6V0B TMEM199 TCIRG1

3.29e-03491273GO:0090533
GeneOntologyCellularComponentapical part of cell

ANO1 TCIRG1 ABCC5 SLC26A9 SLC39A10 SLC22A2 NPC1L1 CD81 OCLN VCAM1

3.32e-0359212710GO:0045177
DomainOlfact_rcpt

OR5M9 OR4C11 OR6K2 OR5D14 OR6C65 OR5M8 OR1J2 OR4K14 OR51E2 OR52R1 OR6V1 OR4S1 OR51M1 OR52E6 OR52N5 OR52E4 OR2D3 OR4F21 OR2Z1 OR7G3 OR4F6

1.47e-1339312421IPR000725
DomainGPCR_Rhodpsn_7TM

GPR3 OR5M9 OR4C11 OR6K2 OR5D14 CYSLTR1 OR6C65 OR5M8 ACKR4 OR1J2 OR4K14 OR51E2 OR52R1 OR6V1 OR4S1 OR51M1 OR52E6 OR52N5 OR52E4 RRH OR2D3 OR4F21 OR2Z1 OR7G3 OR4F6

1.75e-1267012425IPR017452
Domain7tm_1

GPR3 OR5M9 OR4C11 OR6K2 OR5D14 CYSLTR1 OR6C65 OR5M8 ACKR4 OR1J2 OR4K14 OR51E2 OR52R1 OR6V1 OR4S1 OR51M1 OR52E6 OR52N5 OR52E4 RRH OR2D3 OR4F21 OR2Z1 OR7G3 OR4F6

2.20e-1267712425PF00001
DomainG_PROTEIN_RECEP_F1_1

GPR3 OR5M9 OR4C11 OR6K2 OR5D14 CYSLTR1 OR6C65 OR5M8 ACKR4 OR1J2 OR4K14 OR51E2 OR52R1 OR6V1 OR4S1 OR51M1 OR52E6 OR52N5 OR52E4 RRH OR2D3 OR4F21 OR2Z1 OR7G3 OR4F6

2.84e-1268512425PS00237
DomainG_PROTEIN_RECEP_F1_2

GPR3 OR5M9 OR4C11 OR6K2 OR5D14 CYSLTR1 OR6C65 OR5M8 ACKR4 OR1J2 OR4K14 OR51E2 OR52R1 OR6V1 OR4S1 OR51M1 OR52E6 OR52N5 OR52E4 RRH OR2D3 OR4F21 OR2Z1 OR7G3 OR4F6

3.44e-1269112425PS50262
DomainGPCR_Rhodpsn

GPR3 OR5M9 OR4C11 OR6K2 OR5D14 CYSLTR1 OR6C65 OR5M8 ACKR4 OR1J2 OR4K14 OR51E2 OR52R1 OR6V1 OR4S1 OR51M1 OR52E6 OR52N5 OR52E4 RRH OR2D3 OR4F21 OR2Z1 OR7G3 OR4F6

3.55e-1269212425IPR000276
DomainPtc/Disp

NPC1L1 PTCH2 DISP1

2.33e-0591243IPR003392
DomainPatched

NPC1L1 PTCH2 DISP1

2.33e-0591243PF02460
DomainPlug_translocon

SEC61A2 SEC61A1

4.37e-0521242PF10559
DomainSecY_su_dom

SEC61A2 SEC61A1

4.37e-0521242IPR023201
DomainSecY

SEC61A2 SEC61A1

4.37e-0521242PF00344
DomainSECY_1

SEC61A2 SEC61A1

4.37e-0521242PS00755
DomainSECY_2

SEC61A2 SEC61A1

4.37e-0521242PS00756
Domain-

SEC61A2 SEC61A1

4.37e-05212421.10.3370.10
DomainTranslocon_Sec61/SecY_plug_dom

SEC61A2 SEC61A1

4.37e-0521242IPR019561
DomainSecY_CS

SEC61A2 SEC61A1

4.37e-0521242IPR030659
DomainSecY/SEC61-alpha

SEC61A2 SEC61A1

4.37e-0521242IPR002208
DomainSSD

NPC1L1 PTCH2 DISP1

7.78e-05131243IPR000731
DomainSSD

NPC1L1 PTCH2 DISP1

7.78e-05131243PS50156
DomainDynein_heavy_chain_D4_dom

DNAH3 DNAH12 DNAH6

9.86e-05141243IPR024317
DomainDynein_heavy_dom-2

DNAH3 DNAH12 DNAH6

9.86e-05141243IPR013602
DomainDHC_N2

DNAH3 DNAH12 DNAH6

9.86e-05141243PF08393
DomainAAA_8

DNAH3 DNAH12 DNAH6

9.86e-05141243PF12780
DomainATPase_dyneun-rel_AAA

DNAH3 DNAH12 DNAH6

9.86e-05141243IPR011704
DomainAAA_5

DNAH3 DNAH12 DNAH6

9.86e-05141243PF07728
DomainDHC_fam

DNAH3 DNAH12 DNAH6

1.23e-04151243IPR026983
DomainDynein_heavy_dom

DNAH3 DNAH12 DNAH6

1.23e-04151243IPR004273
DomainDynein_heavy

DNAH3 DNAH12 DNAH6

1.23e-04151243PF03028
DomainMYELIN_PLP_1

GPM6A GPM6B

1.31e-0431242PS00575
DomainMyelin_PLP

GPM6A GPM6B

1.31e-0431242IPR001614
DomainCarb_kinase_FGGY_CS

GK GK2

1.31e-0431242IPR018483
DomainMyelin_PLP_CS

GPM6A GPM6B

1.31e-0431242IPR018237
DomainMyelin_PLP

GPM6A GPM6B

1.31e-0431242PF01275
DomainMYELIN_PLP_2

GPM6A GPM6B

1.31e-0431242PS01004
DomainPLP

GPM6A GPM6B

1.31e-0431242SM00002
DomainGlycerol_kin

GK GK2

2.60e-0441242IPR005999
DomainAAA+_ATPase

DNAH3 ABCA2 ABCC5 DNAH12 MCM9 DNAH6

4.01e-041441246IPR003593
DomainAAA

DNAH3 ABCA2 ABCC5 DNAH12 MCM9 DNAH6

4.01e-041441246SM00382
DomainLRRC8_Pannexin-like

LRRC8E LRRC8C

4.32e-0451242IPR021040
DomainFGGY_KINASES_2

GK GK2

4.32e-0451242PS00445
DomainVPS10

SORCS1 SORCS3

4.32e-0451242SM00602
DomainFGGY_KINASES_1

GK GK2

4.32e-0451242PS00933
DomainPannexin_like

LRRC8E LRRC8C

4.32e-0451242PF12534
DomainCarb_kinase_FGGY_C

GK GK2

4.32e-0451242IPR018485
DomainSortilin_C

SORCS1 SORCS3

4.32e-0451242PF15901
DomainSortilin-Vps10

SORCS1 SORCS3

4.32e-0451242PF15902
DomainVPS10

SORCS1 SORCS3

4.32e-0451242IPR006581
DomainSortilin_N

SORCS1 SORCS3

4.32e-0451242IPR031778
DomainSortilin_C

SORCS1 SORCS3

4.32e-0451242IPR031777
DomainSterol-sensing

NPC1L1 PTCH2

4.32e-0451242PF12349
DomainFGGY_C

GK GK2

6.45e-0461242PF02782
DomainCarb_kinase_FGGY_N

GK GK2

6.45e-0461242IPR018484
DomainCarb_kinase_FGGY

GK GK2

8.98e-0471242IPR000577
DomainPKD

SORCS1 SORCS3

8.98e-0471242PF00801
DomainFGGY_N

GK GK2

8.98e-0471242PF00370
DomainSialidases

SORCS1 SORCS3

1.53e-0391242IPR011040
DomainPKD

SORCS1 SORCS3

2.31e-03111242PS50093
DomainPKD_dom

SORCS1 SORCS3

2.31e-03111242IPR000601
Domain-

SORCS1 SORCS3

2.31e-031112422.60.40.670
DomainDynein_HC_stalk

DNAH3 DNAH6

3.78e-03141242IPR024743
DomainMT

DNAH3 DNAH6

3.78e-03141242PF12777
PathwayREACTOME_OLFACTORY_SIGNALING_PATHWAY

OR5M9 OR4C11 OR5G3 OR6K2 OR5D14 OR6C65 OR5M8 OR1J2 OR4K14 OR51E2 OR52R1 OR6V1 OR4S1 OR51M1 OR52E6 OR52N5 OR52E4 OR2D3 OR4F21 OR2Z1 OR7G3 OR4F6

4.74e-144179622M4072
PathwayKEGG_OLFACTORY_TRANSDUCTION

OR5M9 OR4C11 OR6K2 OR5D14 OR6C65 OR5M8 OR1J2 OR4K14 OR51E2 OR52R1 OR6V1 OR4S1 OR51M1 OR52E6 OR52N5 OR52E4 OR2D3 OR2Z1 OR7G3 OR4F6

1.28e-123899620M14091
PathwayREACTOME_SENSORY_PERCEPTION

OR5M9 OR4C11 OR5G3 OR6K2 OR5D14 OR6C65 OR5M8 OR1J2 OR4K14 OR51E2 OR52R1 OR6V1 OR4S1 OR51M1 SCN1B SCN3A OR52E6 OR52N5 OR52E4 OR2D3 OR4F21 OR2Z1 OR7G3 OR4F6

4.03e-126369624M41834
Pubmed

Different evolutionary processes shaped the mouse and human olfactory receptor gene families.

OR5M9 OR4C11 OR5G3 OR6K2 OR5D14 OR6C65 OR5M8 OR9A1P OR51E2 OR52R1 OR51M1 OR52N5 OR52E4 OR2D3 OR4F21 OR2Z1 OR7G3 OR4F6

6.08e-163401281811875048
Pubmed

The olfactory receptor gene superfamily of the mouse.

OR5M9 OR4C11 OR5G3 OR6K2 OR5D14 OR6C65 OR5M8 OR9A1P OR51E2 OR52R1 OR51M1 OR52N5 OR52E4 OR2D3 OR4F21 OR2Z1 OR7G3 OR4F6

6.08e-163401281811802173
Pubmed

A unified nomenclature for vertebrate olfactory receptors.

OR5M9 OR4C11 OR5G3 OR6K2 OR5D14 OR6C65 OR5M8 OR9A1P OR51E2 OR52R1 OR51M1 OR52N5 OR52E4 OR2D3 OR4F21 OR2Z1 OR7G3 OR4F6

7.08e-163431281832295537
Pubmed

Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.

OR5M9 OR4C11 OR5G3 OR6K2 OR5D14 OR6C65 OR5M8 OR9A1P OR51E2 OR52R1 OR51M1 OR52N5 OR52E4 OR2D3 OR4F21 OR2Z1 OR7G3 OR4F6

8.24e-163461281814611657
Pubmed

The human olfactory receptor gene family.

OR5M9 OR4C11 OR5G3 OR6K2 OR5D14 OR5M8 OR1J2 OR4K14 OR51E2 OR52R1 OR6V1 OR4S1 OR51M1 OR52E6 OR52N5 OR52E4 OR2D3 OR2Z1 OR7G3 OR4F6

1.23e-145411282014983052
Pubmed

DEFOG: a practical scheme for deciphering families of genes.

OR5M9 OR5D14 OR5M8 OR1J2 OR4K14 OR52E6 OR2D3 OR2Z1 OR7G3

1.32e-07219128912213199
Pubmed

Interrogating the protein interactomes of RAS isoforms identifies PIP5K1A as a KRAS-specific vulnerability.

HK1 SCAMP1 TMEM199 ATG2B ABCC5 CACHD1 SLC39A10 ECPAS PIGU OCLN PCDH9

1.35e-064671281130194290
Pubmed

Odorant and vomeronasal receptor genes in two mouse genome assemblies.

OR5M9 OR4C11 OR4F21 OR2Z1 OR7G3

8.20e-0674128515081110
Pubmed

Systematic protein-protein interaction mapping for clinically relevant human GPCRs.

ABCA2 ATP6V0B TMEM199 PIGG PIGU TSPAN33 TMEM259 SCN1B DHCR24 RETREG1 CD81 PCDH9

1.09e-056971281228298427
Pubmed

BioID reveals an ATG9A interaction with ATG13-ATG101 in the degradation of p62/SQSTM1-ubiquitin clusters.

PRUNE2 WDR7 SCAMP1 POLR3B DHCR24 OCLN SEC61A1 AP3S2

1.13e-05285128834369648
Pubmed

Chromosomal mapping of the human M6 genes.

GPM6A GPM6B

1.34e-05212828661015
Pubmed

Control of translocation through the Sec61 translocon by nascent polypeptide structure within the ribosome.

SEC61A2 SEC61A1

1.34e-052128218480044
Pubmed

SORCS1 and SORCS3 control energy balance and orexigenic peptide production.

SORCS1 SORCS3

1.34e-052128229440124
Pubmed

SCN1Bβ mutations that affect their association with Kv4.3 underlie early repolarization syndrome.

KCND3 SCN1B

1.34e-052128230160358
Pubmed

Isolation of two human cDNAs, HLP3 and HLP4, homologous to the neuron-specific calcium-binding protein genes.

VSNL1 HPCAL4

1.34e-052128210520747
Pubmed

Identification and characterization of SorCS, a third member of a novel receptor family.

SORCS1 SORCS3

1.34e-052128210600506
Pubmed

Pain-enhancing mechanism through interaction between TRPV1 and anoctamin 1 in sensory neurons.

TRPV1 ANO1

1.34e-052128225848051
Pubmed

Identification of GPM6A and GPM6B as potential new human lymphoid leukemia-associated oncogenes.

GPM6A GPM6B

1.34e-052128224916915
Pubmed

The CD81 tetraspanin facilitates instantaneous leukocyte VLA-4 adhesion strengthening to vascular cell adhesion molecule 1 (VCAM-1) under shear flow.

CD81 VCAM1

1.34e-052128214532283
Pubmed

Seladin-1/DHCR24 Is Neuroprotective by Associating EAAT2 Glutamate Transporter to Lipid Rafts in Experimental Stroke.

SLC1A2 DHCR24

1.34e-052128226628388
Pubmed

Glycerol kinase 2 is essential for proper arrangement of crescent-like mitochondria to form the mitochondrial sheath during mouse spermatogenesis.

GK GK2

1.34e-052128230662012
Pubmed

Comparative Host Interactomes of the SARS-CoV-2 Nonstructural Protein 3 and Human Coronavirus Homologs.

TMEM199 PIGG SLC39A10 PIGU SPINT2 TMEM259 EIF5B SEC61A1

1.48e-05296128834186245
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH3 DNAH12 DNAH6

1.72e-051412839373155
Pubmed

Functional suppression of Kcnq1 leads to early sodium channel remodelling and cardiac conduction system dysmorphogenesis.

KCND3 KCNH2 SCN1B

1.72e-0514128323542581
Pubmed

Study of the association of adrenomedullin and basic-fibroblast growth factors with the peripheral arterial blood flow and endothelial dysfunction biomarkers in type 2 diabetic patients with peripheral vascular insufficiency.

ADM VCAM1

4.02e-053128225287126
Pubmed

Structural basis for modulation of human NaV1.3 by clinical drug and selective antagonist.

SCN1B SCN3A

4.02e-053128235277491
Pubmed

Oversulfated chondroitin sulfate plays critical roles in the neuronal migration in the cerebral cortex.

CHST14 CHST15

4.02e-053128218819920
Pubmed

EMA: a developmentally regulated cell-surface glycoprotein of CNS neurons that is concentrated at the leading edge of growth cones.

GPM6A GPM6B

4.02e-05312821286213
Pubmed

Molecular cloning of M6: identification of a PLP/DM20 gene family.

GPM6A GPM6B

4.02e-05312828398137
Pubmed

Amyloidosis causes downregulation of SorLA, SorCS1 and SorCS3 expression in mice.

SORCS1 SORCS3

4.02e-053128231095505
Pubmed

Expression of members of the proteolipid protein gene family in the developing murine central nervous system.

GPM6A GPM6B

4.02e-05312828807448
Pubmed

Glycerol kinase-like proteins cooperate with Pld6 in regulating sperm mitochondrial sheath formation and male fertility.

GK GK2

4.02e-053128228852571
Pubmed

The three sorCS genes are differentially expressed and regulated by synaptic activity.

SORCS1 SORCS3

4.02e-053128215009648
Pubmed

Maturational changes in cell surface antigen expression in the mouse retina and optic pathway.

GPM6A GPM6B

4.02e-05312829554989
Pubmed

Hidden Twins: SorCS Neuroreceptors Form Stable Dimers.

SORCS1 SORCS3

4.02e-053128228827148
Pubmed

Identification of functional voltage-gated Na(+) channels in cultured human pulmonary artery smooth muscle cells.

SCN1B SCN3A

4.02e-053128216052353
Pubmed

Mice Expressing Minimally Humanized CD81 and Occludin Genes Support Hepatitis C Virus Uptake In Vivo.

CD81 OCLN

4.02e-053128227928007
Pubmed

Mutation analysis of candidate genes SCN1B, KCND3 and ANK2 in patients with clinical diagnosis of long QT syndrome.

KCND3 SCN1B

4.02e-053128218052691
Pubmed

Spatiotemporal expression analysis of the growth factor receptor SorCS3.

SORCS1 SORCS3

4.02e-053128224715575
Pubmed

The calcium-activated chloride channel anoctamin 1 acts as a heat sensor in nociceptive neurons.

TRPV1 ANO1

4.02e-053128222634729
Pubmed

Establishment and Dysfunction of the Blood-Brain Barrier.

ABCA2 ABCC5 SLC1A2 SLC22A2

4.13e-0552128426590417
Pubmed

Blood-Brain Barrier: From Physiology to Disease and Back.

ABCA2 ABCC5 SLC1A2 SLC22A2 OCLN

4.49e-05105128530280653
Pubmed

Hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel susceptibility genes for Alzheimer's disease.

PRUNE2 SCAMP1 ARID2

5.30e-0520128319668339
Pubmed

Kv4.3 Modulates the Distribution of hERG.

KCND3 KCNH2

8.02e-054128229259226
Pubmed

LRRC8 Proteins Form Volume-Regulated Anion Channels that Sense Ionic Strength.

LRRC8E LRRC8C

8.02e-054128226824658
Pubmed

The genes for the human VPS10 domain-containing receptors are large and contain many small exons.

SORCS1 SORCS3

8.02e-054128211499680
Pubmed

Stimulation of adhesion molecule expression in human endothelial cells (HUVEC) by adrenomedullin and corticotrophin.

ADM VCAM1

8.02e-054128214534081
Pubmed

Expression of human factors CD81, claudin-1, scavenger receptor, and occludin in mouse hepatocytes does not confer susceptibility to HCV entry.

CD81 OCLN

8.02e-054128221551950
Pubmed

The CysLT2R receptor mediates leukotriene C4-driven acute and chronic itch.

TRPV1 CYSLTR1

8.02e-054128233753496
Pubmed

The Sec61 complex is located in both the ER and the ER-Golgi intermediate compartment.

SEC61A2 SEC61A1

8.02e-054128210212142
Pubmed

Role of transmembrane 4 superfamily (TM4SF) proteins CD9 and CD81 in muscle cell fusion and myotube maintenance.

ITGA7 CD81

8.02e-054128210459022
Pubmed

Association of sodium voltage-gated channel genes polymorphisms with epilepsy risk and prognosis in the Saudi population.

SCN1B SCN3A

8.02e-054128235801810
Pubmed

LRRC8A:C/E Heteromeric Channels Are Ubiquitous Transporters of cGAMP.

LRRC8E LRRC8C

8.02e-054128233171122
Pubmed

Identification, tissue specific expression, and chromosomal localisation of several human dynein heavy chain genes.

DNAH3 DNAH6

8.02e-054128211175280
Pubmed

Brugada Syndrome

KCND3 KCNH2 SCN1B

9.31e-0524128320301690
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

WDR7 SCAMP1 ATG2B SLC39A10 PIGU RETREG1 OCLN SLC12A7 COG4

1.09e-04504128934432599
Pubmed

Patched1 and Patched2 inhibit Smoothened non-cell autonomously.

PTCH2 DISP1

1.33e-045128227552050
Pubmed

Renal Deletion of LRRC8/VRAC Channels Induces Proximal Tubulopathy.

LRRC8E LRRC8C

1.33e-045128235777784
Pubmed

The glycerol kinase gene family: structure of the Xp gene, and related intronless retroposons.

GK GK2

1.33e-04512827987308
Pubmed

LRRC8 involved in B cell development belongs to a novel family of leucine-rich repeat proteins.

LRRC8E LRRC8C

1.33e-045128215094057
Pubmed

Identification of LRRC8 heteromers as an essential component of the volume-regulated anion channel VRAC.

LRRC8E LRRC8C

1.33e-045128224790029
Pubmed

Tetraspanins CD81 and CD82 facilitate α4β1-mediated adhesion of human erythroblasts to vascular cell adhesion molecule-1.

CD81 VCAM1

1.33e-045128223704882
Pubmed

Calnexin and other factors that alter translocation affect the rapid binding of ubiquitin to apoB in the Sec61 complex.

SEC61A2 SEC61A1

1.33e-04512829565615
Pubmed

Functional Characterization of Rare Variants Implicated in Susceptibility to Lone Atrial Fibrillation.

KCNH2 SCN1B

1.33e-045128226129877
Pubmed

Case-control association study of polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, SCN3A, SCN1B, and SCN2B and epilepsy.

SCN1B SCN3A

1.33e-045128224337656
Pubmed

Light-Controlled Affinity Purification of Protein Complexes Exemplified by the Resting ZAP70 Interactome.

TRBC2 TRBC1

2.00e-046128230863395
Pubmed

Sequence and evolution of the human T-cell antigen receptor beta-chain genes.

TRBC2 TRBC1

2.00e-04612823860845
Pubmed

Deletion of SERP1/RAMP4, a component of the endoplasmic reticulum (ER) translocation sites, leads to ER stress.

SEC61A2 SEC61A1

2.00e-046128216705175
Pubmed

Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.

PLOD3 CHST14 PIGG PIGU PIK3IP1 ARID2 FAM210B SEC61A1

2.01e-04430128816303743
Pubmed

ER-export and ARFRP1/AP-1-dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication.

LRRC8E LRRC8C WDR7 SCAMP1 ABCC5 PIGG SLC39A10 SPINT2 OCLN SLC12A7 SEC61A1 PCDH9

2.14e-049521281238569033
Pubmed

Breaking down the barrier: the effects of HIV-1 on the blood-brain barrier.

OCLN VCAM1

2.79e-047128221641584
Pubmed

Isolation of several human axonemal dynein heavy chain genes: genomic structure of the catalytic site, phylogenetic analysis and chromosomal assignment.

DNAH3 DNAH12

2.79e-04712829256245
Pubmed

Retrotransposition of glycerol kinase-related genes from the X chromosome to autosomes: functional and evolutionary aspects.

GK GK2

2.79e-047128210444329
Pubmed

Regulatory mechanisms in T cell receptor signalling.

TRBC2 TRBC1

2.79e-047128229789755
Pubmed

TspanC8 tetraspanins differentially regulate the cleavage of ADAM10 substrates, Notch activation and ADAM10 membrane compartmentalization.

TSPAN33 CD81

3.71e-048128226686862
Pubmed

Expression of multiple chondroitin/dermatan sulfotransferases in the neurogenic regions of the embryonic and adult central nervous system implies that complex chondroitin sulfates have a role in neural stem cell maintenance.

CHST14 CHST15

3.71e-048128218079434
Pubmed

HIV-1 gp120 and drugs of abuse: interactions in the central nervous system.

OCLN VCAM1

3.71e-048128222591361
Pubmed

The identification of novel proteins that interact with the GLP-1 receptor and restrain its activity.

ATP6V0B PIGG CD81

4.04e-0439128323864651
Pubmed

Transcriptomic and quantitative proteomic analysis of transporters and drug metabolizing enzymes in freshly isolated human brain microvessels.

ABCA2 SLC1A2

4.76e-049128221707071
Pubmed

Genome-wide association study of smoking initiation and current smoking.

GRIN2A SLC1A2

4.76e-049128219268276
Pubmed

Expression pattern of neuronal and skeletal muscle voltage-gated Na+ channels in the developing mouse heart.

SCN1B SCN3A

4.76e-049128215746173
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

LRRC8C ABCA2 PLOD3 CHST14 ERMP1 CACHD1 PIGG SLC39A10 ITGA7 PIGU CELSR3 TMEM259 SEC61A1

5.02e-0412011281335696571
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

CHST14 SCAMP1 TMEM199 TCIRG1 ERMP1 PIGU SPINT2 DHCR24 CD81 SLC12A7 PCDH9 IPO11

5.66e-0410611281233845483
Pubmed

Claudin association with CD81 defines hepatitis C virus entry.

CD81 OCLN

5.93e-0410128220375010
Pubmed

Transcallosal Projections Require Glycoprotein M6-Dependent Neurite Growth and Guidance.

GPM6A GPM6B

5.93e-0410128224917275
Pubmed

Blood-brain barrier abnormalities caused by HIV-1 gp120: mechanistic and therapeutic implications.

OCLN VCAM1

5.93e-0410128222448134
Pubmed

TspanC8 tetraspanins regulate ADAM10/Kuzbanian trafficking and promote Notch activation in flies and mammals.

TSPAN33 CD81

5.93e-0410128223091066
Pubmed

Loss of HAI-2 in mice with decreased prostasin activity leads to an early-onset intestinal failure resembling congenital tufting enteropathy.

SPINT2 OCLN

5.93e-0410128229617460
Pubmed

HIV-1 Vpu inhibits accumulation of the envelope glycoprotein within clathrin-coated, Gag-containing endosomes.

CD81 AP3S2

5.93e-0410128218076669
Pubmed

Transfer of cGAMP into Bystander Cells via LRRC8 Volume-Regulated Anion Channels Augments STING-Mediated Interferon Responses and Anti-viral Immunity.

LRRC8E LRRC8C

8.66e-0412128232277911
Pubmed

The role of assembly in insulin's biosynthesis.

SEC61A2 SEC61A1

8.66e-041212829631292
Pubmed

Nav1.2 haplodeficiency in excitatory neurons causes absence-like seizures in mice.

SCN1B SCN3A

8.66e-0412128230175250
Pubmed

ESYT1 tethers the ER to mitochondria and is required for mitochondrial lipid and calcium homeostasis.

TMEM199 PIGU DHCR24 RETREG1 OCLN SEC61A1

8.67e-04299128637931956
Pubmed

Expression patterns of Hedgehog signalling pathway members during mouse palate development.

PTCH2 DISP1

1.02e-0313128216168717
Pubmed

Structure and Roles of V-type ATPases.

ATP6V0B TCIRG1

1.02e-0313128232001091
Pubmed

Helios modulates the maturation of a CA1 neuronal subpopulation required for spatial memory formation.

VSNL1 GRIN2A

1.19e-0314128231712124
Pubmed

Network organization of the human autophagy system.

PLOD3 HK1 ATG2B ECPAS SEC61A2 EIF5B GAN

1.21e-03437128720562859
Pubmed

CFTR interactome mapping using the mammalian membrane two-hybrid high-throughput screening system.

HK1 CHST14 SCAMP1 OR5M8 LMBR1L CYB561D1 SMYD3

1.26e-03440128735156780
Pubmed

Neuronal interleukin-16 (NIL-16): a dual function PDZ domain protein.

GRIN2A KCND3

1.37e-0315128210479680
Pubmed

Integrins in the mouse myotome: developmental changes and differences between the epaxial and hypaxial lineage.

ITGA7 VCAM1

1.37e-0315128215366018
InteractionCANX interactions

LRRC8E LRRC8C DNAH3 ABCA2 CHST14 TMEM199 CACHD1 GRIN2A PIGG SLC39A10 SPPL2B FBXL4 RNF123 CHST15 LMBR1L PTPRN TMEM259 KCNH2 DHCR24 RETREG1 SLC12A7 SEC61A1

7.50e-07126110822int:CANX
InteractionHTR3A interactions

LRRC8E GPM6A LRRC8C ABCA2 ERMP1 PIGG SPPL2B

1.86e-061081087int:HTR3A
InteractionTSPAN15 interactions

LRRC8E LRRC8C ABCA2 SCAMP1 ERMP1 PIGG SLC39A10 PIGU DHCR24 FAM210B

2.35e-0627610810int:TSPAN15
InteractionMFSD4A interactions

LRRC8E SLC39A10 ECPAS SEC61A2 GK DHCR24 OCLN COG4 IPO11

3.45e-062251089int:MFSD4A
InteractionP2RY8 interactions

ABCA2 ERMP1 PIGG SLC39A10 ECPAS PIGU COG4 IPO11

5.47e-061791088int:P2RY8
InteractionGPR173 interactions

ERMP1 PIGG SLC39A10 PIGU TMEM259

7.77e-06511085int:GPR173
InteractionFPR2 interactions

LRRC8E LRRC8C ERMP1 PIGG GK DHCR24 IPO11

9.50e-061381087int:FPR2
InteractionOR4N2 interactions

LRRC8E ABCA2 TMEM259 SLC12A7

1.67e-05291084int:OR4N2
InteractionSYP interactions

GPM6A SCAMP1 ECPAS SEC61A2 GK DHCR24 MIEF1

2.29e-051581087int:SYP
InteractionCHRNA4 interactions

LRRC8E VSNL1 ERMP1 PIGG SPPL2B LMBR1L OCLN

2.38e-051591087int:CHRNA4
InteractionSLC2A9 interactions

ECPAS GK COG4 IPO11

2.83e-05331084int:SLC2A9
InteractionP2RY2 interactions

ERMP1 PIGG SLC39A10 PIGU TMEM259 DHCR24

3.11e-051121086int:P2RY2
InteractionGPR182 interactions

LRRC8E ABCA2 ERMP1 PIGG SLC39A10 ECPAS SEC61A2 TMEM259 DHCR24 COG4 IPO11

3.32e-0545510811int:GPR182
InteractionCLGN interactions

ABCA2 ABCC5 ITGA7 SPPL2B FBXL4 LMBR1L SLC12A7 SEC61A1

3.92e-052351088int:CLGN
InteractionDNAH6 interactions

HK1 EPX GAN DNAH6

4.03e-05361084int:DNAH6
InteractionTSPAN17 interactions

GPM6A TMEM199 PIGU FAM210B SLC12A7

4.23e-05721085int:TSPAN17
InteractionSLAMF1 interactions

ATG2B CACHD1 ITGA7 GK GK2 OCLN

5.76e-051251086int:SLAMF1
InteractionEPX interactions

EPX GAN DNAH6

7.97e-05161083int:EPX
InteractionSLC26A9 interactions

SLC26A9 RNF123

8.51e-0531082int:SLC26A9
InteractionHLA-DQA1 interactions

ABCA2 CHST14 ERMP1 ITGA7 TMEM259 SLC12A7

8.84e-051351086int:HLA-DQA1
InteractionCLEC2D interactions

LRRC8E ABCA2 ERMP1 PIGG SLC39A10 SPPL2B CLDN19

9.29e-051971087int:CLEC2D
InteractionSIDT2 interactions

LRRC8E LRRC8C ERMP1 SPPL2B SLC12A7 AP3S2

1.08e-041401086int:SIDT2
InteractionCCR6 interactions

ERMP1 PIGG SLC39A10 SPPL2B IPO11

1.17e-04891085int:CCR6
InteractionVIPR1 interactions

ERMP1 PIGG ECPAS PIGU SEC61A2 DHCR24 IPO11

1.19e-042051087int:VIPR1
InteractionRXFP1 interactions

LRRC8E ABCC5 ERMP1 RNF123 SLC12A7

1.23e-04901085int:RXFP1
InteractionLPAR1 interactions

LRRC8E ERMP1 SLC39A10 SPPL2B PIGU DHCR24 FAM210B

1.38e-042101087int:LPAR1
InteractionATG9A interactions

PRUNE2 WDR7 SCAMP1 TCIRG1 POLR3B DHCR24 RETREG1 OCLN SEC61A1 AP3S2

1.40e-0444510810int:ATG9A
InteractionCHRM4 interactions

ECPAS GK CD81 COG4 IPO11

1.51e-04941085int:CHRM4
InteractionTEX13B interactions

VSNL1 ARID2 HPCAL4

1.60e-04201083int:TEX13B
InteractionDUOXA2 interactions

LRRC8E GPM6A ECPAS OCLN

1.61e-04511084int:DUOXA2
InteractionENTPD2 interactions

ERMP1 PIGG SPPL2B SEC61A2 OCLN

1.84e-04981085int:ENTPD2
InteractionGPR45 interactions

ABCA2 PIGG SLC39A10 ECPAS PIGU DHCR24 COG4 IPO11

2.13e-043001088int:GPR45
InteractionTTYH1 interactions

LRRC8E LRRC8C ABCA2 ERMP1 SPPL2B DHCR24 FAM210B SLC12A7

2.13e-043001088int:TTYH1
InteractionGJA8 interactions

ATP6V0B ERMP1 TMEM121 TSPAN33 PTPRN CLDN19

2.24e-041601086int:GJA8
InteractionATP2A3 interactions

ABCA2 TCIRG1 ERMP1 GRIN2A SPPL2B SPINT2 DHCR24

2.55e-042321087int:ATP2A3
Cytoband11p15.4

ADM OR52R1 OR51M1 OR52E6 OR52N5 OR52E4 OR2D3

1.62e-06200128711p15.4
CytobandEnsembl 112 genes in cytogenetic band chr11p15

OR51E2 ADM OR52R1 OR51M1 OR52E6 OR52N5 OR52E4 OR2D3 CD81

3.13e-055641289chr11p15
Cytoband10q23-q25

SORCS1 SORCS3

4.61e-054128210q23-q25
GeneFamilyDyneins, axonemal

DNAH3 DNAH12 DNAH6

8.23e-0517923536
GeneFamilyOlfactory receptors, family 52

OR52R1 OR52E6 OR52N5 OR52E4

1.12e-0449924165
GeneFamilySolute carriers

SLC35D2 SLC26A9 FLVCR2 SLC39A10 SLC1A2 SLC7A14 SLC35F3 SLC22A2 SLC12A7

1.82e-04395929752
GeneFamilyVolume regulated anion channel subunits

LRRC8E LRRC8C

2.54e-0459221158
GeneFamilyGlycerol kinases

GK GK2

3.79e-046922568
GeneFamilyOlfactory receptors, family 4

OR4C11 OR4K14 OR4S1 OR4F21 OR4F6

5.12e-04129925151
GeneFamilyOlfactory receptors, family 6

OR6K2 OR6C65 OR6V1

2.23e-0351923153
GeneFamilyOlfactory receptors, family 5

OR5M9 OR5G3 OR5D14 OR5M8

2.57e-03112924152
GeneFamilyGlycosyl transferases group 1 domain containing|Phosphatidylinositol glycan anchor biosynthesis

PIGG PIGU

5.05e-0321922680
GeneFamilyV-type ATPases

ATP6V0B TCIRG1

6.04e-0323922415
CoexpressionAtlascerebral cortex

GPM6A GPM6B GPR3 ABCA2 VSNL1 WDR7 GRIN2A SLC39A10 SLC1A2 SLC7A14 TMEM121 SORCS1 SEC61A2 CELSR3 SLC35F3 PTPRN SCN3A SORCS3 PCDH9 HPCAL4 PGBD5

5.67e-06142810521cerebral cortex
CoexpressionAtlasDevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#3_top-relative-expression-ranked_500

GPM6B ANO1 FZD1 KCND3 SCN3A

1.50e-05631055gudmap_developingKidney_e15.5_Ureteral Smooth Musc_500_k3
CoexpressionAtlasBM Top 100 - temporal lobe

GPM6A VSNL1 GRIN2A SLC1A2 HPCAL4

3.30e-05741055BM Top 100 - temporal lobe
CoexpressionAtlasgudmap_RNAseq_e15.5_Podocytes_2500_K3

GPM6A GPM6B ABCA2 KCNH2 RETREG1

3.76e-05761055gudmap_RNAseq_e15.5_Podocytes_2500_K3
CoexpressionAtlasdev gonad_e12.5_M_InterstitTestis_Sma_k-means-cluster#4_top-relative-expression-ranked_1000

GPM6A VSNL1 GRIN2A KCND3 SORCS3 PCDH9 VCAM1

4.62e-051911057gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_k4_1000
CoexpressionAtlasdev lower uro neuro_e15.5_PelvicGanglion_Sox10_k-means-cluster#1_top-relative-expression-ranked_1000

LRRC8C SLC7A14 SORCS1 CHST15 SCN3A PCDH9 AP3S2

8.65e-052111057gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k1_1000
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

VSNL1 HK1 WDR7 RNF123 LMBR1L SLC12A7 PCDH9 PGBD5

3.35e-0817512481d8aab491dcc27ea5dbfb6462d18ee280b21a05e
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

VSNL1 HK1 WDR7 RNF123 LMBR1L SLC12A7 PCDH9 PGBD5

3.35e-081751248427a7ee92fe16a90625946492062d37aa0f7235b
ToppCell18-Distal-Epithelial-Neuroendocrine|Distal / Age, Tissue, Lineage and Cell class

PRUNE2 SORCS1 SPINT2 PTPRN KCND3 SCN3A NPC1L1 SMYD3

5.15e-081851248f8fc7b12b4e18d23d84e95488be93c4352d325f3
ToppCellPCW_10-12-Epithelial-Epithelial_neuroendo-epi_neuroendocrine2[NE2]_(12)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

PRUNE2 GPM6A SORCS1 SLC35F3 PTPRN KCND3 SCN3A RETREG1

6.86e-0819212484d3a1c267739b1479217144656986972fc86db43
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PRUNE2 VSNL1 OR1J2 SORCS1 SORCS3 SLC12A7 DNAH6

8.28e-0718312473ebe334ad570e3525341badb558f369c61daf3d3
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PRUNE2 SORCS1 PTPRN KCND3 KCNH2 SCN3A RETREG1

9.23e-071861247b45cce768e4bf91da194fd9660cab7520dfb15ac
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PRUNE2 SORCS1 SLC35F3 PTPRN KCND3 KCNH2 SCN3A

9.91e-071881247c4c3b21ab723b0e9beff9ec84f8d68485f771528
ToppCell18-Airway-Epithelial-Neuroendocrine|Airway / Age, Tissue, Lineage and Cell class

PRUNE2 GPM6A PTPRN KCND3 KCNH2 SCN3A SMYD3

1.03e-061891247144beb01b908f2cd0e04513fb84d817e0c3c124e
ToppCell15-Trachea-Epithelial-Neuroendocrine|Trachea / Age, Tissue, Lineage and Cell class

SLC26A9 CELSR3 SLC35F3 PTPRN KCND3 KCNH2 SCN3A

1.10e-06191124776311fa5f3ae9bb27cf04387a8c92300f2888c28
ToppCellTracheal-10x5prime-Stromal-Schwann-Schwann_Myelinating|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

GPM6A GPM6B ABCA2 TMEM121 SORCS1 CLDN19 PGBD5

1.45e-0619912472b567b6fd8addf059bbf2b72c55a7647aefdc595
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Radial_glial-gliogenic/outer_RGCs_and_astrocytes|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

LRRC8C TCIRG1 ERMP1 CNBD2 SORCS3 CLDN19

5.22e-0615712462c1219ee19a6246a3b9f5c2c1a37f26ea934a822
ToppCellNS-critical-LOC-Myeloid-Basophil|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ADAMTS3 SORCS1 FZD1 KCNH2 CYB561D1 PCDH9

5.82e-0616012468a4746463ca1976f7d6de803496c851249ced797
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-T_cells-ILC3|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

POLR3B CELSR3 OR51M1 PTCH2 TRBC1 PCDH9

6.70e-061641246631ec9f54475dcc9d6b1c5bf6917e7fda4671034
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EECs|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GRIN2A DNAH12 CELSR3 PTPRN SCN3A DNAH6

6.94e-0616512464b4e75ad0eb0a6b00c30a000ec6267e23ba2e496
ToppCellCOVID-19-Heart-Neuronal|COVID-19 / Disease (COVID-19 only), tissue and cell type

GPM6B SLC7A14 SORCS1 RETREG1 SORCS3 PCDH9

7.69e-06168124688c2c574f428c2502b5fe099bd73b0758f668ef6
ToppCelldroplet-Heart-HEART-1m-Endothelial-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPM6A FLVCR2 ACKR4 POLR3B SCN3A LRRD1

9.09e-0617312469dc7746a84f0e268a7c061e1bbcd5e31903034dc
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PRUNE2 OR1J2 SORCS1 SORCS3 SLC12A7 DNAH6

1.10e-051791246b35a7f8115c997c390201da01d7cb10b10769aec
ToppCell15-Distal-Epithelial-Neuroendocrine|Distal / Age, Tissue, Lineage and Cell class

PRUNE2 SLC7A14 SLC35F3 PTPRN KCND3 SCN3A

1.10e-051791246bc04789f0fbd293fdcea66acba8cf227af251b7a
ToppCelldroplet-Lung-nan-3m-Mesenchymal-fibroblast_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPM6B GPR3 FZD1 ADM SCN3A VCAM1

1.29e-05184124689ac32e374a4379e4a6c6ea7603b1378b77c147f
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PRUNE2 OR1J2 SORCS1 SORCS3 SLC12A7 DNAH6

1.29e-0518412469cc5c588f7c6631b3fb8a522214a09ca32947e72
ToppCelldroplet-Lung-nan-3m-Mesenchymal-Alveolar_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPM6B GPR3 FZD1 ADM SCN3A VCAM1

1.29e-0518412464df6027fa635996c1eddb920f88a5265772df1cd
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PIK3IP1 RETREG1 SORCS3 TRBC2 TRBC1 HPCAL4

1.29e-0518412465350b58aa9979631228835d11eb45ddf81d08bff
ToppCelldroplet-Lung-nan-3m-Mesenchymal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPM6B FZD1 ADM SCN3A CD81 VCAM1

1.41e-05187124651f1c6bac3abae1d20aa8ac46642bcdbc02cb0a2
ToppCellfacs-Heart-RA-3m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPM6A ACKR4 SPINT2 OCLN SLC12A7 IPO11

1.46e-0518812464ddb11a90bf3baa7237bde304db44dfcc56aed52
ToppCellfacs-Heart-RA-3m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPM6A ACKR4 SPINT2 OCLN SLC12A7 IPO11

1.46e-051881246e47e66906922d5c69b1aafe28face0787d3fc563
ToppCell3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell-Neuroendocrine|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLC26A9 OR51E2 PTPRN KCND3 KCNH2 SCN3A

1.55e-05190124640d8b3403f4e38436b961cd3a2e69826cbae3042
ToppCell3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell-Neuroendocrine-Neuroendocrine_L.0.7.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLC26A9 OR51E2 PTPRN KCND3 KCNH2 SCN3A

1.55e-051901246f6cbf6d292f488ada5f7581e1dceba6198b933d1
ToppCell3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLC26A9 OR51E2 PTPRN KCND3 KCNH2 SCN3A

1.55e-051901246a9a705455019e28d655636de73b07540798f82e6
ToppCellP03-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

VSNL1 ADAMTS3 CYSLTR1 FZD1 RETREG1 CD81

1.55e-051901246979b1476fd2692fde977ce56257315fcfc8a01d5
ToppCellPCW_13-14-Epithelial-Epithelial_neuroendo-epi_neuroendocrine2[NE2]_(12)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

PRUNE2 GPM6A SORCS1 KCND3 SCN3A RETREG1

1.59e-05191124619832ddd559a353e1618fe853d79e3edfec6dcda
ToppCelldroplet-Heart-nan-18m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPM6A SPINT2 OCLN SLC12A7 VCAM1 IPO11

1.64e-0519212460b9b2eaed45456d7d74ce78a64ef4a26ac2458fb
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TMEM199 SLC35F3 SLC22A2 SORCS3 VCAM1 PGBD5

1.64e-051921246b18ae7337eaad1315a5b0ee81c75f7606bd3c7fe
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TMEM199 SLC35F3 SLC22A2 SORCS3 VCAM1 PGBD5

1.64e-051921246b2d9cc2a013012b25b458d4dc77be63e1c2144da
ToppCelldroplet-Lung-nan-21m-Mesenchymal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPM6B FZD1 ADM SCN3A CD81 VCAM1

1.64e-051921246e429e8fbc48ad26204a0197b9129e58be56bd7b6
ToppCelldroplet-Lung-nan-21m-Mesenchymal-Alveolar_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPM6B FZD1 ADM SCN3A CD81 VCAM1

1.69e-051931246ac4270b26f5dc7ff2220a109e5aae5a113893211
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-D|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PRUNE2 GPM6B ABCA2 SLC7A14 KCND3 PCDH9

1.69e-051931246947200ef6c3a2e35ad7e6b4af29d92384bdf73f5
ToppCelldroplet-Lung-nan-21m-Mesenchymal-fibroblast_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPM6B FZD1 ADM SCN3A CD81 VCAM1

1.69e-0519312467a09739d0b07dcd615cce2da93fd169cc92e566d
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 FZD1 SPINT2 SLC22A2 RETREG1 VCAM1

1.74e-05194124670185c0b8e0f4e896645b17a243482ba3cdf4a5d
ToppCellTracheal-10x5prime-Stromal-Schwann|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

GPM6B ABCA2 SORCS1 SORCS3 CLDN19 PCDH9

1.85e-051961246b6226163d9fc93ecfff2115bb74408303a000490
ToppCell(7)_MNP-(7)_Macrophage|(7)_MNP / Spleen cell shreds - cell class (v1) and cell subclass (v1)

ABCC5 PIK3IP1 SCN1B CD81 TRBC2 VCAM1

1.85e-05196124671ec157163278ad259c190051926bf41e4ecef46
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SLC26A9 SLC7A14 OR51E2 CELSR3 KCNH2 SCN3A

1.85e-05196124695544097577f20ed7f4144bd940471cde0617554
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

VSNL1 SLC7A14 CELSR3 PTPRN KCNH2 SCN3A

1.85e-0519612464bdc304c0c9d8bebe1a6a8a27e44acd1e8113725
ToppCell(08)_PNEC|World / shred by cell type and Timepoint

PRUNE2 SLC26A9 PTPRN KCNH2 SCN3A PGBD5

1.85e-0519612462ee37155c03cd5009427a4bffe6c80ed2ac6939e
ToppCellSepsis-Bac-SEP-Lymphocyte-T/NK-CD8+_T_naive|Bac-SEP / Disease, condition lineage and cell class

PIK3IP1 DNAH12 KCND3 KCNH2 TRBC2 HPCAL4

1.95e-051981246a9a009e5eeb935232034635ad4a3c27d83c081ac
ToppCellNeuronal-Excitatory-eB(RORB)-SEMA3E-|Neuronal / cells hierarchy compared to all cells using T-Statistic

PRUNE2 OR1J2 SORCS1 SORCS3 SLC12A7 DNAH6

2.07e-0520012461a3d29a580d1b405a74869a1da3e818c581fc559
ToppCellNeuronal-Excitatory-eB(RORB)-SEMA3E---L4-6|Neuronal / cells hierarchy compared to all cells using T-Statistic

PRUNE2 OR1J2 SORCS1 SORCS3 SLC12A7 DNAH6

2.07e-0520012466f9ed8fe9cda91185c3a1a675353e11b8fec6ef1
ToppCellNeuronal-Excitatory-eB(RORB)-SEMA3E--|Neuronal / cells hierarchy compared to all cells using T-Statistic

PRUNE2 OR1J2 SORCS1 SORCS3 SLC12A7 DNAH6

2.07e-05200124686705dfc05b3e1576543b93883c88fb55b742855
ToppCellNeuronal-Excitatory-eB(RORB)-SEMA3E|Neuronal / cells hierarchy compared to all cells using T-Statistic

PRUNE2 OR1J2 SORCS1 SORCS3 SLC12A7 DNAH6

2.07e-052001246db194b4f524fd008b3c5b4b6014b436190a1b87a
ToppCellLymphoid-NK_cells|World / shred on cell class and cell subclass (v4)

GK2 TRBC2 TRBC1 HPCAL4 SMYD3

3.31e-051311245b0b62392d1637601115e85f5584fdcd5dbd0c778
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DNAH3 DNAH12 CELSR3 SCN3A TRBC2

6.30e-05150124553de595376a9fc92491dfd58ff25938b0bf79903
ToppCellFrontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

SLC1A2 PTCH2 TRBC2 TRBC1 HPCAL4

6.30e-0515012459d5bbdca19da60e1a2121ef64ec8e1375a5dbf6d
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B-B_cell|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DNAH3 DNAH12 CELSR3 SCN3A TRBC2

6.30e-051501245e4b40b3243ed26d0c46bf196ac06e148834e7ed2
ToppCellFrontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

SLC1A2 PTCH2 TRBC2 TRBC1 HPCAL4

6.92e-051531245b37a1ecad389d2848b8ca4d287823e8048207420
ToppCellInt-URO-Lymphocyte-T_NK-CD4_CTL|Int-URO / Disease, Lineage and Cell Type

ACKR4 TRBC2 TRBC1 HPCAL4 SMYD3

6.92e-051531245fdc7dfa8f4db90bfdc7180bf178cf6d2dd064d97
ToppCellSevere-B_naive-5|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

SPPL2B FBXL4 SCN3A RETREG1 OCLN

7.82e-051571245a57ee4a6febdff3ee3d1645836695e6e7c055cf8
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SORCS1 PTPRN KCND3 SCN3A RETREG1

8.30e-0515912457747cef94c55144fddcd024a7495318357f1351b
ToppCellIPF-Epithelial-PNEC|IPF / Disease state, Lineage and Cell class

SLC26A9 PTPRN KCND3 SCN3A PCDH9

8.30e-051591245adec82df944fe8699a69ca52534353bef100f2f9
ToppCellCOPD-Epithelial-PNEC|World / Disease state, Lineage and Cell class

PTPRN KCND3 KCNH2 SCN3A PCDH9

8.55e-051601245cdea93317b0ebb801ddbe73bca6149ce2c727f16
ToppCellIPF-Epithelial-PNEC|World / Disease state, Lineage and Cell class

SLC26A9 PTPRN KCND3 SCN3A PCDH9

8.81e-051611245133833729ba8b6d3eef326590ca7476b17602cbb
ToppCellHealthy_donor-CD8+_T_naive|World / disease group, cell group and cell class (v2)

PIK3IP1 RETREG1 TRBC2 DNAH6 HPCAL4

8.81e-0516112458a61395af33132783a0a37956c6f821aba5d3b1e
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

GPR3 SORCS3 DNAH6 PCDH9 HPCAL4

9.07e-051621245373513f9d0e5007b2e10a8b78d4909dcce9e3b62
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CACHD1 CD81 SLC12A7 PCDH9 VCAM1

1.05e-041671245f01b96173deda0239fa482989873cf308e49d48c
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CACHD1 CD81 SLC12A7 PCDH9 VCAM1

1.05e-0416712455fc85a05124cd2324e1b8ff940193880f83cd8af
ToppCellfacs-Marrow-B-cells-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACHD1 SPPL2B TSPAN33 RNF123 FAM210B

1.08e-04168124517fb9426eeea407b26fb895b8397faca95b7552d
ToppCellfacs-Marrow-B-cells-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACHD1 SPPL2B TSPAN33 RNF123 FAM210B

1.08e-041681245a61b39884851384cffd430079040546d125b2b40
ToppCellfacs-Heart-RA-18m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPM6A GRIN2A SPINT2 OCLN IPO11

1.08e-04168124506dc5b2d356d3a9454b10bba6f3b9ead2a0a7d46
ToppCellfacs-Heart-RA-18m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPM6A GRIN2A SPINT2 OCLN IPO11

1.08e-0416812451002f058a340763e3d8de0bd1f0547a903526ec6
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

VSNL1 FZD1 LMBR1L SCN3A PGBD5

1.11e-0416912457cb1b87be66a22fe5731bb1b55bc515920fe3e8b
ToppCellHealthy_donor-CD8+_T_naive|Healthy_donor / disease group, cell group and cell class (v2)

PIK3IP1 RETREG1 TRBC2 DNAH6 HPCAL4

1.11e-04169124566216758e581365f10c2a66714d83a606ad23af0
ToppCelldroplet-Thymus-nan-3m-Myeloid|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN33 SORCS1 CELSR3 SCN3A VCAM1

1.17e-04171124525493a4a7b636920e2cfd984542cc500709c9dcf
ToppCelldroplet-Thymus-nan-3m-Myeloid-professional_antigen_presenting_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN33 SORCS1 CELSR3 SCN3A VCAM1

1.17e-041711245508b41e3ad2638f9dd546d251b13ff60fc8c3207
ToppCellwk_20-22-Epithelial-Proximal_epithelial-intermediate_neuroendocrine|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

PRUNE2 CELSR3 PTPRN KCND3 SCN3A

1.17e-041711245b7cddb8f726a43fb8a37f3e67a3f722e2178fd7a
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPM6A ACKR4 SCN1B SCN3A DNAH6

1.30e-041751245f6e1d7297a4dbb38e1ab4f738d91f0e62abaee69
ToppCelldroplet-Marrow-nan-24m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPPL2B TSPAN33 ADM RNF123 FAM210B

1.34e-041761245f92063b72ebfeb9b192281dc63d6bf2759c78554
ToppCellfacs-Trachea-24m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l54|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GPM6A ACKR4 SLC22A2 DNAH6 HPCAL4

1.34e-041761245460cb302c5b3d609c65b924e1d4e8ea057a68485
ToppCellfacs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l32-30|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GPM6B ITGA7 SORCS1 KCNH2 CLDN19

1.37e-04177124559cf56c385c324f0844f20003d2b5049a2791e45
ToppCelldroplet-Marrow-nan-24m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACHD1 SPPL2B TSPAN33 RNF123 FAM210B

1.41e-041781245b4e15c176875cd226854a0019495309d02730c42
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

PIK3IP1 SPINT2 RETREG1 TRBC2 HPCAL4

1.41e-04178124573936c2e7e8855b4ab65cad425686513dba331a3
ToppCellMid-temporal_gyrus_(MTG)|World / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAMTS3 CACHD1 SLC35F3 KCND3 DNAH6

1.41e-041781245ad187db4c40b9078d54dd915c143e0172b2f47b8
ToppCellControl-T/NK-NK|Control / Disease group,lineage and cell class (2021.01.30)

CACHD1 TMEM121 TRBC2 TRBC1 PCDH9

1.41e-041781245079fd19bdeed86bf985c4083af432432d66ad546
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC35F3 SLC22A2 SORCS3 VCAM1 PGBD5

1.41e-041781245a0ab20c588e7d43d0320d4779d9ab95c1c86e297
ToppCellCOPD-Epithelial-PNEC|Epithelial / Disease state, Lineage and Cell class

PTPRN KCND3 KCNH2 SCN3A PCDH9

1.45e-041791245988d0853c391da1e5004f73f3678047418d3f6d3
ToppCellwk_20-22-Epithelial-Proximal_epithelial-Pulmonary_neuroendocrine|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

SLC7A14 PTPRN KCND3 SCN3A NPC1L1

1.49e-04180124557689ccbbd44c0e78e061edd87d3102c5f2dcc9a
ToppCelldroplet-Marrow-BM_(NON-STC)-30m-Lymphocytic-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN33 SPINT2 FAM210B EIF5B VCAM1

1.49e-04180124554e3f289a37d4cfbfca4fb284c3b52e9c7d9da97
ToppCelldroplet-Marrow-BM_(NON-STC)-30m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN33 SPINT2 FAM210B EIF5B VCAM1

1.49e-041801245bfc8568d57034dd9c9e07edae94479a48ca0706d
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS3 KCND3 LRRD1 HPCAL4 PGBD5

1.52e-0418112457af469f5bcb9b1ab3f35b2758bf2afb87e8eba57
ToppCell367C-Lymphocytic-CD4_T-cell-CD4+_Naive_T_cell_/_CD4+_Trm_cell|367C / Donor, Lineage, Cell class and subclass (all cells)

PIK3IP1 RETREG1 SORCS3 TRBC2 TRBC1

1.52e-0418112459b155a74e68e485039a5195144a12833f2f75058
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Macroglial-Schwann_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPM6B SORCS1 FZD1 CLDN19 PCDH9

1.56e-041821245d568a8aec7e27ce632e248baea2ccd0e8dd255ac
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Macroglial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPM6B SORCS1 FZD1 CLDN19 PCDH9

1.56e-041821245e89cc30db8e5c77a8bbddd1d5a4b5af09f1ccd67
ToppCellwk_15-18-Hematologic_Lymphocytic-T_&_ILC-ILCP|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

PIK3IP1 SCN1B RETREG1 TRBC2 TRBC1

1.56e-0418212456bd48c5d60a259719f65cacee4b8135247e78fa9
ToppCellwk_15-18-Epithelial-Proximal_epithelial-GHRL+_neuroendocrine|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

SLC7A14 CELSR3 SLC35F3 PTPRN NPC1L1

1.60e-0418312458820cfed27b292bc0bc9cde4005219ed41900552
ToppCelldroplet-Heart-nan-18m-Neuronal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC1A2 SORCS1 SLC22A2 CLDN19 DNAH6

1.60e-0418312451701c8c212f1fdb6e4764375542a203e19753d14
ToppCelldroplet-Heart-4Chambers-18m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPM6A SPINT2 OCLN SLC12A7 VCAM1

1.60e-0418312456c4a09c02e30e1f24dde39f8cb8c5b453826ee2e
ToppCellE17.5-Epithelial-airway_epithelial_cell|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

DNAH3 ITGA7 TSPAN33 DNAH12 SPINT2

1.60e-04183124507cebb0e186e1bff14ac2a6bb6f8412d4aaa2350
ToppCell3'-GW_trimst-1.5-LargeIntestine-Hematopoietic-T_cells|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PIK3IP1 SCN1B RETREG1 TRBC2 TRBC1

1.60e-041831245f079179f2984def91ddf0b33d7949d5ecdbd380d
ToppCellMesenchymal_cells-Osteoblasts|Mesenchymal_cells / Lineage and Cell class

ANO1 FLVCR2 KCNH2 SCN3A PGBD5

1.60e-041831245d6b52d52fe9a7a6c798947f05420d79fe12e4662
ToppCellE17.5-Epithelial-airway_epithelial_cell-club_cell|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

DNAH3 ITGA7 TSPAN33 DNAH12 SPINT2

1.60e-041831245e8e85e5be909f9cd85a6a041190bfcb855dfa1a4
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

PIK3IP1 RETREG1 SORCS3 TRBC2 TRBC1

1.60e-041831245f2ef110bf29b1a8276ef216238363e542db262c1
ToppCell3'-GW_trimst-1.5-LargeIntestine-Hematopoietic-T_cells-ILCP|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PIK3IP1 SCN1B RETREG1 TRBC2 TRBC1

1.60e-04183124549e8ee16e4f677f9f649e2a2faf1b9b16c5a27e7
ToppCellPCW_10-12-Immune_Lymphocytic-Immune_Lymphocytic_NK/ILC-im_ILC3_(12)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SORCS1 SCN1B RETREG1 TRBC2 TRBC1

1.65e-0418412453e9d75af578297950e469f23fb2d28393a2feef8
Drugdiarylpropionitrile

TRPV1 SLC1A2 DHCR24 OCLN

1.14e-05261244ctd:C492519
DrugLynestrenol [52-76-6]; Up 200; 14uM; PC3; HT_HG-U133A

PRUNE2 FLVCR2 KCND3 FAM210B SCN3A RETREG1 HPCAL4 PGBD5

1.23e-0519612486756_UP
DrugRh(H2O)4ATP

HK1 GK GK2

1.29e-0591243CID003082848
Drugcarbinoxamine

KCNH2 SLC22A2

2.94e-0521242ctd:C004649
Drugnifekalant

KCNH2 SLC22A2

2.94e-0521242ctd:C076259
DrugDroperidol

KCNH2 SLC22A2

2.94e-0521242ctd:D004329
Drugdiphenylguanidine

KCNH2 SLC22A2

2.94e-0521242ctd:C027773
Drugclebopride

KCNH2 SLC22A2

2.94e-0521242ctd:C014417
Drugbopindolol

KCNH2 SLC22A2

2.94e-0521242ctd:C036007
Drugmebeverine

KCNH2 SLC22A2

2.94e-0521242ctd:C005096
Drugmepazine

KCNH2 SLC22A2

2.94e-0521242ctd:C100190
Drugdyclonine

KCNH2 SLC22A2

2.94e-0521242ctd:C100063
Drugdexbrompheniramine

KCNH2 SLC22A2

2.94e-0521242ctd:C015121
DrugBromhexine

KCNH2 SLC22A2

2.94e-0521242ctd:D001964
Drugpridinol

KCNH2 SLC22A2

2.94e-0521242ctd:C009185
Drug3-7a

TRPV1 CYSLTR1 GRIN2A KCNH2

4.31e-05361244CID011987860
Diseasehydroquinone sulfate measurement

ABCA2 SORCS1

4.58e-0531162EFO_0021157
Diseaseglycerol kinase deficiency (implicated_via_orthology)

GK GK2

4.58e-0531162DOID:0060363 (implicated_via_orthology)
DiseaseSpeech Disorders

HK1 GRIN2A

9.15e-0541162C0037822
DiseaseBrugada Syndrome (disorder)

KCND3 KCNH2 SCN1B

1.13e-04241163C1142166
Diseasetumor necrosis factor ligand superfamily member 6, soluble form measurement

RNF123 CELSR3

3.18e-0471162EFO_0020797
Diseaseepilepsy (implicated_via_orthology)

GRIN2A ITGA7 KCNH2 SCN3A SLC12A7

4.74e-041631165DOID:1826 (implicated_via_orthology)
DiseaseOther specified cardiac arrhythmias

KCND3 SCN1B

8.23e-04111162C0348626
DiseaseNodal rhythm disorder

KCND3 SCN1B

8.23e-04111162C0264893
DiseaseEctopic rhythm

KCND3 SCN1B

8.23e-04111162C1399226
DiseaseCARDIAC CONDUCTION DEFECT, NONSPECIFIC (disorder)

KCND3 SCN1B

8.23e-04111162C2748542
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

SCN1B SCN3A

9.86e-04121162DOID:0060170 (implicated_via_orthology)
DiseaseBrugada Syndrome 1

KCND3 SCN1B

1.16e-03131162C4551804
Diseasecystic fibrosis associated meconium ileus

SLC26A9 TRBC2

1.35e-03141162EFO_0004608
DiseaseSinus Node Dysfunction (disorder)

KCND3 SCN1B

1.56e-03151162C0428908
Diseaseprostate carcinoma, type 2 diabetes mellitus

SEC61A2 SLC22A2 AP3S2

1.64e-03591163EFO_0001663, MONDO_0005148
DiseaseBenign Neoplasm

TRPV1 KCNH2 OCLN

2.46e-03681163C0086692
DiseaseNeoplasms

TRPV1 KCNH2 OCLN

2.46e-03681163C0027651
DiseaseHbA1c measurement, response to sulfonylurea

GRIN2A OR2Z1

3.06e-03211162EFO_0004541, EFO_0007922
Diseasedepressive disorder (implicated_via_orthology)

GPM6A GPM6B

3.36e-03221162DOID:1596 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
LVVYLMATVTVLLGM

CYB561D1

171

Q8N8Q1
MVSLLATGAAMVLYD

AACS

341

Q86V21
CTMQELIGLYVTMEE

COG4

411

Q9H9E3
ISTLEVLYMLTEMGD

ARID2

416

Q68CP9
VHYILQEVVMGGMVL

AP3S2

116

P59780
VMILTYALMNDGVTG

CACHD1

376

Q5VU97
RALMVVAVLLGFVAM

CLDN19

81

Q8N6F1
IAMGLSVAVAFSVML

DISP1

986

Q96F81
GIYILIAVGAVMMFV

CD81

61

P60033
IGSIINYMVVMGVVL

ERMP1

416

Q7Z2K6
YVRVMDMGLLELTIT

ATG2B

1306

Q96BY7
MKLVSVALMYLGSLA

ADM

1

P35318
LLAALMIVSMVSAGV

ERVK-21

76

P61571
MKDIGYSDIMVLCVL

PRTFDC1

61

Q9NRG1
AVMLIFMSYDGIVAV

OR6K2

211

Q8NGY2
LIDMYTEGIVDLTEM

GSTA5

91

Q7RTV2
ILGIMVFIATIVYIM

OCLN

181

Q16625
NIVATYLIMAGMISI

RRH

26

O14718
YLIMAGMISIISNII

RRH

31

O14718
MYVITVVGNLGMIII

OR5D14

36

Q8NGL3
ITYLLSVSGNMIIIM

OR6C65

31

A6NJZ3
YLGTSMKALIQMLEI

ACKR4

191

Q9NPB9
MIIMFVDSYDVILAG

PLOD3

106

O60568
GMETVLLVVMAYDRF

OR52E4

111

Q8NGH9
DVIVALMYTVVTPML

OR1J2

271

Q8NGS2
TGTYILIDMVLNRMA

PTPRN

916

Q16849
EMVLLIAMAFDRYVA

OR4F21

111

O95013
RSVMSIIDVVAIMPY

KCND3

256

Q9UK17
QLIRALTMIGAYEIM

LRRD1

831

A4D1F6
LTMIGAYEIMDKITA

LRRD1

836

A4D1F6
MLEIIEAIYKMVGTV

HPCAL4

121

Q9UM19
IVSSMAMLIGARYIS

GK3P

536

Q14409
AGAAVIAMVHYLMVL

GPM6A

221

P51674
VVMSTYLGVMGRVLL

IPO11

786

Q9UI26
SICVMLIGSLMYASI

KCNH2

641

Q12809
RLAIQEALSMMVGAY

ECPAS

456

Q5VYK3
AILLVMGVDVMFISL

OR51E2

201

Q9H255
LMGVAEGVLLVLMSY

OR2Z1

106

Q8NG97
GLMVVVFTVMLDLVL

OR51M1

211

Q9H341
VMESIVLVAMAFDRY

OR52E6

111

Q96RD3
EMVLLIAMAFDRYVA

OR4F6

111

Q8NGB9
IKLACMDTYVLGIIM

OR4K14

186

Q8NGD5
YMVGLIVVANSGMIS

OR4S1

191

Q8NGB4
DYLTIMIAIIAGAMV

PCDH9

811

Q9HC56
IMGAMVQIITYRDFL

EPX

421

P11678
YMVVSSGVDMPAILL

FAM210B

116

Q96KR6
EVMLVVVGMIILISY

GYPE

61

P15421
VAMMVPNYALIAEIS

DNAH12

1376

Q6ZR08
VLAEYLTVAMLMIGV

LRRC8E

26

Q6NSJ5
GVIIYRISMAAALAM

ANO1

536

Q5XXA6
AAMLGIATLAVKRMY

MIEF1

36

Q9NQG6
TEMAIFSMGVVILLA

OR2D3

211

Q8NGH3
IFYMGTVVGNMLIIV

OR4C11

31

Q6IEV9
YVLGITMMVIIIAIG

PIK3IP1

171

Q96FE7
GAGATVIALLIYMMA

GPM6B

231

Q13491
MVSGMYLGELVRLIL

HK1

296

P19367
MMYVGSLVVIICLSF

PIGU

231

Q9H490
AEMSLVLVGVLAMAF

GPR3

106

P46089
VIGMSYVMILRAVLQ

OR52R1

216

Q8NGF1
AFMGNTIIIVMVIAD

OR6V1

36

Q8N148
ELALMGVMAVDRYVA

OR9A1P

111

Q8NGU1
SIVMILVDTVGFMAL

NPC1L1

1171

Q9UHC9
EVTLTEMKAFLGYMI

PGBD5

161

Q8N414
SIYALSMAVMLILKA

ABCC5

916

O15440
TVFMIKYLMTLIVGI

FZD1

601

Q9UP38
VRMIMLGYAKSISLI

ADAMTS3

306

O15072
AMMVPNYALIAEVIL

DNAH6

1596

Q9C0G6
IVSSMVMLIGARYIS

GK2

536

Q14410
TVAMMVPDYALIGEI

DNAH3

1551

Q8TD57
CVMIEDYDVIASMIG

FBXL4

461

Q9UKA2
LYSLDEAVIMTGVMT

DHCR24

271

Q15392
LEVVARQLGMYMVTV

SLC1A2

306

P43004
EGISVMVMREILDYI

GAN

76

Q9H2C0
MVMREILDYIFSGQI

GAN

81

Q9H2C0
FIVSSMVMLIGARYI

GK

541

P32189
VTMLMVDAVVYGILT

ABCA2

896

Q9BZC7
ETTLVVYIMTLVGMV

FLVCR2

376

Q9UPI3
VILALVGMEAIMSEF

TMEM259

356

Q4ZIN3
VMVYLDPMAVVAEGV

ITGA7

1066

Q13683
VLVIVMNGTMFLLAA

CELSR3

2691

Q9NYQ7
MRVYGTCTLVLMALV

SLC12A7

251

Q9Y666
MGITMAYEIVCLVNA

SLC22A2

441

O15244
VTAGMFLYVALVDML

SLC39A10

766

Q9ULF5
SGVLMLMALDRYVAI

OR52N5

121

Q8NH56
GLIIMVSYICILMTI

OR5G3

211

P0C626
EMVLLIAMAFDRYVA

OR4F3;

111

Q6IEY1
GMYLVKLAVAMVLAG

MCM9

316

Q9NXL9
GIGQMAATIMILYVS

SLC35D2

61

Q76EJ3
LTLIAMRMEDSGIYV

VCAM1

276

P19320
VISTLELMVAEDYMI

PRUNE2

2946

Q8WUY3
MIITIGQAIVYVMTG

SEC61A2

121

Q9H9S3
VSLVVMITMLVLGIY

SLC26A9

411

Q7LBE3
GVLGRVYETVVMLML

LMBR1L

146

Q6UX01
VYHLISVMILGRVIM

RETREG1

116

Q9H6L5
AMLMLLSVVFVGLAV

SORCS3

1126

Q9UPU3
VFVGLENGILVMMAY

OR7G3

106

Q8NG95
MGSLIYLLVELTQTM

EIF5B

831

O60841
LIVLVLAMMTVELFG

PTCH2

991

Q9Y6C5
GIMMIIIAALFTASA

SCAMP1

261

O15126
LAIYMVTVAGNLGMI

OR5M8

31

Q8NGP6
VVILSIVGMFLAEMI

SCN3A

1596

Q9NY46
LTIGCRQLVEMEYTM

SWT1

861

Q5T5J6
AVYMITLLGNIGMII

OR5M9

31

Q8NGP3
AILAIAGIVMMTYAD

SLC35F3

211

Q8IY50
VGEELTICYLDMLMT

SMYD3

231

Q9H7B4
ELGLYQLAMDIIIMI

CNBD2

16

Q96M20
MFAVIVASSGLLLMI

CHST14

46

Q8NCH0
LIIMTLVMASYILSG

CHST15

86

Q7LFX5
AIGMIMVVTAAFLVS

CYSLTR1

231

Q9Y271
DLIEMMSIGTLLAYT

SLC7A14

406

Q8TBB6
ISMVMVAVGVYARLM

TSPAN33

36

Q86UF1
LAELYVMVRAMEGEL

TMEM199

191

Q8N511
MLEIIEAIYKMVGTV

VSNL1

121

P62760
VTSMYNEILMLGAKL

TRPV1

306

Q8NER1
MIITIGQSIVYVMTG

SEC61A1

121

P61619
TLYAVLVSALVLMAM

TRBC1

156

P01850
SLLEVLDGAVMMYNL

RNF123

746

Q5XPI4
VMVLILFLGASMVYL

SPINT2

206

O43291
AIYGIIMAIVISNMA

ATP6V0B

101

Q99437
LVIMGSMAVMDAYLV

TMEM121

16

Q9BTD3
SIVSEIMMYVLIVVL

SCN1B

156

Q07699
LDYNMVIIFIMAVGT

SPPL2B

171

Q8TCT7
IGYGASMLLLERLMI

POLR3B

1056

Q9NW08
MAVGLLKAMYQELVT

ZNF570

1

Q96NI8
TLYAVLVSALVLMAM

TRBC2

156

A0A5B9
VLSGVFTIMAVDMYL

TMEM217

16

Q8N7C4
DIYSMMVGTVVVLEV

PIGG

431

Q5H8A4
SAMLMLLSVVFVGLA

SORCS1

1101

Q8WY21
VEVMDIIMYCLEGSL

WDR7

1326

Q9Y4E6
AVMTVAILLVMEGLS

TCIRG1

781

Q13488
MGVKLEIFRMIIYLT

PET100

1

P0DJ07
VFTDYLSVAMLMIGV

LRRC8C

26

Q8TDW0
MIGEVVYQRAVMAVG

GRIN2A

496

Q12879