Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity involved in cardiac muscle cell action potential

CACNA1C CACNA2D1

9.43e-055622GO:0086007
GeneOntologyMolecularFunctionfatty-acyl-CoA synthase activity

ACSM3 ACSM5

2.62e-048622GO:0004321
GeneOntologyBiologicalProcesspositive regulation of lipoprotein transport

LRP2 PGRMC1

2.66e-053622GO:0140077
DomainNUT

NUTM1 NUTM2B NUTM2A

3.30e-075613IPR024310
DomainNUT_N

NUTM1 NUTM2B NUTM2A

3.30e-075613IPR024309
DomainNUT

NUTM1 NUTM2B NUTM2A

3.30e-075613PF12881
DomainMBT

SCML2 L3MBTL1

3.72e-049612SM00561
DomainMBT

SCML2 L3MBTL1

3.72e-049612PS51079
DomainMBT

SCML2 L3MBTL1

4.64e-0410612PF02820
DomainMbt

SCML2 L3MBTL1

4.64e-0410612IPR004092
DomainAPOBEC_N

AICDA APOBEC3G

6.78e-0412612PF08210
DomainAPOBEC_N

AICDA APOBEC3G

6.78e-0412612IPR013158
Domain-

PLA2R1 MRC2

8.00e-04136122.10.10.10
DomainDynein_heavy_chain_D4_dom

DNAH9 DNAH14

9.31e-0414612IPR024317
DomainFN_type2_col-bd

PLA2R1 MRC2

9.31e-0414612IPR000562
DomainFN2_2

PLA2R1 MRC2

9.31e-0414612PS51092
DomainDynein_HC_stalk

DNAH9 DNAH14

9.31e-0414612IPR024743
DomainMT

DNAH9 DNAH14

9.31e-0414612PF12777
DomainAAA_8

DNAH9 DNAH14

9.31e-0414612PF12780
DomainAPOBEC/CMP_deaminase_Zn-bd

AICDA APOBEC3G

9.31e-0414612IPR016192
Domainfn2

PLA2R1 MRC2

9.31e-0414612PF00040
DomainFN2_1

PLA2R1 MRC2

9.31e-0414612PS00023
DomainFN2

PLA2R1 MRC2

9.31e-0414612SM00059
DomainDHC_fam

DNAH9 DNAH14

1.07e-0315612IPR026983
DomainDynein_heavy_dom

DNAH9 DNAH14

1.07e-0315612IPR004273
DomainCYT_DCMP_DEAMINASES_2

AICDA APOBEC3G

1.07e-0315612PS51747
DomainDynein_heavy

DNAH9 DNAH14

1.07e-0315612PF03028
DomainCytidine_deaminase-like

AICDA APOBEC3G

1.38e-0317612IPR016193
DomainCYT_DCMP_DEAMINASES_1

AICDA APOBEC3G

1.38e-0317612PS00903
DomainCMP_dCMP_Zn-bd

AICDA APOBEC3G

1.38e-0317612IPR002125
DomainAMP-bd_C

ACSM3 ACSM5

1.38e-0317612IPR025110
DomainAMP-binding_C

ACSM3 ACSM5

1.38e-0317612PF13193
DomainSAM_1

SCML2 SGMS1 L3MBTL1

1.43e-0368613PF00536
DomainPept_M10A_stromelysin-type

MMP1 MMP17

1.55e-0318612IPR016293
DomainPG_binding_1

MMP1 MMP17

1.92e-0320612PF01471
DomainPeptidoglycan-bd-like

MMP1 MMP17

1.92e-0320612IPR002477
DomainHemopexin-like_dom

MMP1 MMP17

2.54e-0323612IPR000585
DomainHemopexin-like_repeat

MMP1 MMP17

2.54e-0323612IPR018487
DomainM10A_MMP

MMP1 MMP17

2.54e-0323612IPR033739
DomainHemopexin

MMP1 MMP17

2.54e-0323612PF00045
DomainHEMOPEXIN

MMP1 MMP17

2.54e-0323612PS00024
Domain-

MMP1 MMP17

2.54e-03236122.110.10.10
DomainHEMOPEXIN_2

MMP1 MMP17

2.54e-0323612PS51642
DomainHX

MMP1 MMP17

2.54e-0323612SM00120
DomainPept_M10A

MMP1 MMP17

2.54e-0323612IPR021190
DomainPeptidase_M10

MMP1 MMP17

2.77e-0324612PF00413
DomainAMP-binding_CS

ACSM3 ACSM5

3.24e-0326612IPR020845
DomainSAM_DOMAIN

SCML2 SGMS1 L3MBTL1

3.71e-0395613PS50105
DomainRICIN

PLA2R1 MRC2

3.76e-0328612SM00458
DomainAMP_BINDING

ACSM3 ACSM5

3.76e-0328612PS00455
DomainRICIN_B_LECTIN

PLA2R1 MRC2

3.76e-0328612PS50231
DomainSAM

SCML2 SGMS1 L3MBTL1

3.93e-0397613IPR001660
DomainZnMc

MMP1 MMP17

4.02e-0329612SM00235
DomainPeptidase_Metallo

MMP1 MMP17

4.02e-0329612IPR006026
DomainAMP-binding

ACSM3 ACSM5

4.30e-0330612PF00501
DomainRicin_B_lectin

PLA2R1 MRC2

4.30e-0330612IPR000772
DomainAMP-dep_Synth/Lig

ACSM3 ACSM5

4.30e-0330612IPR000873
DomainKringle-like

PLA2R1 MRC2

4.89e-0332612IPR013806
Domain-

SCML2 SGMS1 L3MBTL1

5.04e-031066131.10.150.50
Pubmed

The nuclear DNA deaminase AID functions distributively whereas cytoplasmic APOBEC3G has a processive mode of action.

AICDA APOBEC3G

3.23e-06263217161027
Pubmed

Determinants of sequence-specificity within human AID and APOBEC3G.

AICDA APOBEC3G

3.23e-06263220338830
Pubmed

An Endothelial Hsp70-TLR4 Axis Limits Nox3 Expression and Protects Against Oxidant Injury in Lungs.

TLR4 NOX3

3.23e-06263226905942
Pubmed

Genetic association in female stress urinary incontinence based on proteomic findings: a case-control study.

MMP1 SERPINA5

3.23e-06263230715578
Pubmed

Loss-of-function mutations in the cardiac calcium channel underlie a new clinical entity characterized by ST-segment elevation, short QT intervals, and sudden cardiac death.

CACNA1C CACNA2D1

9.68e-06363217224476
Pubmed

The clinical phenotype of YWHAE-NUTM2B/E positive pediatric clear cell sarcoma of the kidney.

NUTM2E NUTM2B

9.68e-06363226542179
Pubmed

A portable hot spot recognition loop transfers sequence preferences from APOBEC family members to activation-induced cytidine deaminase.

AICDA APOBEC3G

9.68e-06363219561087
Pubmed

The clinicopathologic features of YWHAE-FAM22 endometrial stromal sarcomas: a histologically high-grade and clinically aggressive tumor.

NUTM2B NUTM2A

9.68e-06363222456610
Pubmed

Mutations in the cardiac L-type calcium channel associated with inherited J-wave syndromes and sudden cardiac death.

CACNA1C CACNA2D1

9.68e-06363220817017
Pubmed

The histone chaperone Spt6 is required for activation-induced cytidine deaminase target determination through H3K4me3 regulation.

AICDA SUPT6H

9.68e-06363222843687
Pubmed

TLR4 activation and IL-6-mediated cross talk between adipocytes and mononuclear cells synergistically stimulate MMP-1 expression.

TLR4 MMP1

9.68e-06363221952248
Pubmed

Functional properties of the CaV1.2 calcium channel activated by calmodulin in the absence of alpha2delta subunits.

CACNA1C CACNA2D1

9.68e-06363219106618
Pubmed

EMC chaperone-CaV structure reveals an ion channel assembly intermediate.

CACNA1C CACNA2D1

9.68e-06363237196677
Pubmed

Bacterial infection disrupts established germinal center reactions through monocyte recruitment and impaired metabolic adaptation.

AICDA TLR4

1.93e-05463235182483
Pubmed

The Th1/Tfh-like biased responses elicited by the rASP-1 innate adjuvant are dependent on TRIF and Type I IFN receptor pathways.

AICDA TLR4

1.93e-05463236119026
Pubmed

Histone chaperone Spt6 is required for class switch recombination but not somatic hypermutation.

AICDA SUPT6H

1.93e-05463221518874
Pubmed

Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4).

TLR4 ASTN2

1.93e-0546329989976
Pubmed

Intrinsic B cell TLR-BCR linked coengagement induces class-switched, hypermutated, neutralizing antibody responses in absence of T cells.

AICDA TLR4

1.93e-05463237115935
Pubmed

A genome-wide association study of overall survival in pancreatic cancer patients treated with gemcitabine in CALGB 80303.

CACNA1C DCP1B

1.93e-05463222142827
Pubmed

Phosphorylation directly regulates the intrinsic DNA cytidine deaminase activity of activation-induced deaminase and APOBEC3G protein.

AICDA APOBEC3G

3.22e-05563221659520
Pubmed

Regulation of XIAP Turnover Reveals a Role for USP11 in Promotion of Tumorigenesis.

USP11 SPTA1

3.22e-05563228040451
Pubmed

SMS2 deficiency impairs PKCδ-regulated B cell tolerance in the germinal center.

SGMS1 AICDA

3.22e-05563234469734
Pubmed

Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

PHF2 L3MBTL1 MRC2 ASTN2

3.64e-051026349734811
Pubmed

Identification of Astrotactin2 as a Genetic Modifier That Regulates the Global Orientation of Mammalian Hair Follicles.

TLR4 ASTN2

4.82e-05663226418459
Pubmed

Endotoxin Tolerance Inhibits Lyn and c-Src Phosphorylation and Association with Toll-Like Receptor 4 but Increases Expression and Activity of Protein Phosphatases.

PTPN1 TLR4

6.74e-05763226457672
Pubmed

Multiple mouse chromosomal loci for dynein-based motility.

DNAH9 DNAH14 DYNC1I1

8.68e-05476338812413
Pubmed

Constitutive activation of phosphatidylinositol 3-kinase signaling pathway down-regulates TLR4-mediated tumor necrosis factor-alpha release in alveolar macrophages from asymptomatic HIV-positive persons in vitro.

AKT3 TLR4

8.98e-05863218826950
Pubmed

Transport of the outer dynein arm complex to cilia requires a cytoplasmic protein Lrrc6.

DNAH9 DYNC1I1

1.15e-04963227353389
Pubmed

Genome-wide association analysis identifies susceptibility loci for migraine without aura.

ASTN2 MMP17

1.44e-041063222683712
Pubmed

Association of genetic variants with chronic kidney disease in individuals with different lipid profiles.

PTPN1 ACSM3 TLR4 MMP1

1.71e-0415263419578796
Pubmed

Genetic variation associated with preterm birth: a HuGE review.

TLR4 MMP1

1.76e-041163216301860
Pubmed

Messenger RNA editing in mammals: new members of the APOBEC family seeking roles in the family business.

AICDA APOBEC3G

1.76e-041163212683974
Pubmed

Genome-wide association study of age at menarche in African-American women.

AKT3 UNC13C

2.11e-041263223599027
Pubmed

A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.

GABRR2 CACNA2D1 ASTN2

2.18e-046463320889312
Pubmed

Voltage-activated calcium channel expression profiles in mouse brain and cultured hippocampal neurons.

CACNA1C CACNA2D1

3.34e-041563220188150
Pubmed

Differential neuronal targeting of a new and two known calcium channel β4 subunit splice variants correlates with their regulation of gene expression.

CACNA1C CACNA2D1

3.34e-041563224453333
Pubmed

A growth factor attenuates HIV-1 Tat and morphine induced damage to human neurons: implication in HIV/AIDS-drug abuse cases.

AKT3 NOX3

4.32e-041763221483469
Pubmed

Genome-wide association of serum bilirubin levels in Korean population.

PLA2R1 DCHS2

4.32e-041763220639394
Pubmed

Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction.

SCN3A LRP2

4.85e-041863210827173
Pubmed

Ubiquitous and kidney-specific subunits of vacuolar H+-ATPase are differentially expressed during nephrogenesis.

ATP6V0A4 LRP2

5.41e-041963216177003
Pubmed

Postural changes in blood pressure associated with interactions between candidate genes for chronic respiratory diseases and exposure to particulate matter.

TLR4 MMP1

6.01e-042063219590686
Pubmed

Functional interactions between matrix metalloproteinases and glycosaminoglycans.

MMP1 MMP17

7.29e-042263223421805
Pubmed

Genome-wide pharmacogenomic study of neurocognition as an indicator of antipsychotic treatment response in schizophrenia.

ZFP90 GPR137B

7.29e-042263221107309
Pubmed

Genetic risk factors for periodontitis in a Japanese population.

TLR4 MMP1

7.29e-042263219892918
Pubmed

Matrix metalloproteinases.

MMP1 MMP17

7.29e-042263210419448
Pubmed

Single nucleotide polymorphisms of matrix metalloproteinase 9 (MMP9) and tumor protein 73 (TP73) interact with Epstein-Barr virus in chronic lymphocytic leukemia: results from the European case-control study EpiLymph.

AKT3 AICDA TLR4 MMP1

8.31e-0423163421048031
Pubmed

Brugada Syndrome

CACNA1C CACNA2D1

8.69e-042463220301690
Pubmed

Phosphoproteomics screen reveals akt isoform-specific signals linking RNA processing to lung cancer.

AKT3 SUPT6H

1.18e-032863224462114
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

GPBP1 NUP107 USP11 SUPT6H THAP12

1.22e-0344063534244565
Pubmed

Racial disparity in pathophysiologic pathways of preterm birth based on genetic variants.

TLR4 MMP1 PGRMC1

1.65e-0312863319527514
Pubmed

Preterm birth in Caucasians is associated with coagulation and inflammation pathway gene variants.

TLR4 MMP1 PGRMC1

1.65e-0312863318818748
Cytoband9q33.1

TLR4 ASTN2

6.63e-0596329q33.1
Cytoband17q23.2

MRC2 EFCAB3

9.52e-043363217q23.2
Cytoband10q22.3

NUTM2E NUTM2B

1.61e-034363210q22.3
GeneFamilySterile alpha motif domain containing|MBT domain containing

SCML2 L3MBTL1

2.35e-0494721263
GeneFamilyApolipoprotein B mRNA editing enzyme catalytic subunits

AICDA APOBEC3G

4.29e-0412472406
GeneFamilyDyneins, axonemal

DNAH9 DNAH14

8.77e-0417472536
GeneFamilySterile alpha motif domain containing

SCML2 SGMS1 L3MBTL1

1.55e-0388473760
GeneFamilyEndogenous ligands|Matrix metallopeptidases

MMP1 MMP17

1.76e-0324472891
GeneFamilyCalcium voltage-gated channel subunits

CACNA1C CACNA2D1

2.07e-0326472253
GeneFamilyAcyl-CoA synthetase family

ACSM3 ACSM5

2.07e-032647240
GeneFamilyC-type lectin domain family

PLA2R1 MRC2

6.64e-0347472494
ToppCelldroplet-Kidney-nan-18m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLA2R1 L3MBTL1 MRC2 ASTN2 MMP17 MGAT5B

1.46e-0716963687116c33c5ca8cb1862e103e5607b1df4d264569
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPTA1 SCN3A LRP2 UNC13C DNAH9

4.15e-0616963512bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCelldroplet-Kidney-nan-3m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLA2R1 AKT3 MRC2 FGD6 DYNC1I1

4.53e-06172635073a503dc922e3e3ac3528e249b0f8b74402110b
ToppCelldroplet-Kidney-nan-21m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLA2R1 MRC2 MMP17 MGAT5B DYNC1I1

6.12e-06183635f55081068213cc1cdb2acad58ff10f6b48b44c72
ToppCelldroplet-Lung-30m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PLA2R1 CACNA2D1 MRC2 SCN3A ASTN2

7.72e-06192635ff4b728a55c2550c806c47e9ae3d057c35df8464
ToppCelldroplet-Lung-30m-Mesenchymal-fibroblast-alveolar_fibroblast|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PLA2R1 CACNA2D1 MRC2 SCN3A ASTN2

7.72e-061926352d3790bd80a7f214b37094121a2a86ff16362569
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CACNA1C CACNA2D1 MRC2 UNC13C DYNC1I1

8.12e-06194635011e14d9ed1393275f892060e7708ffadcd0767f
ToppCellPCW_13-14-Mesenchymal|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CACNA1C CACNA2D1 MRC2 UNC13C DYNC1I1

8.75e-0619763573a2085d2682d636726a5432d572ae2a3fbe1c3f
ToppCellPCW_10-12-Mesenchymal|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CACNA1C CACNA2D1 MRC2 UNC13C DYNC1I1

9.19e-06199635a09292de4c4447b8eee55d401808e43b817321cc
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell-D175|Adult / Lineage, Cell type, age group and donor

CACNA1C GABRR2 CACNA2D1 DYNC1I1

9.20e-05167634c4e321bb87512ea839f324c92c0f1afea891483f
ToppCell3'_v3-bone_marrow-Hematopoietic_progenitors-Progenitor_pre-Lymphocytic-T|bone_marrow / Manually curated celltypes from each tissue

ACSM3 KLHL42 NOX3 ACSM5

1.03e-04172634a66402d15853f0c9e3d06394ff9ac08d1da128ff
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MRPS31 CACNA2D1 KLHL42 ASTN2

1.08e-04174634e2243f1e48e3275753a2b3a69d06eefce69a8ded
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-enteroendocrine_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA2D1 SCN3A ASTN2 DNAH9

1.18e-0417863430ca37f70d267cc9b40ca3e211f16d30360c3e6b
ToppCellfacs-Lung-nan-3m-Mesenchymal-fibroblast_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLA2R1 CACNA2D1 MRC2 SCN3A

1.28e-04182634c557de6ccd327c46e0a5423cd9936d78e0abae5f
ToppCellfacs-Lung-nan-3m-Mesenchymal-Alveolar_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLA2R1 CACNA2D1 MRC2 SCN3A

1.28e-04182634dbe4b2557cf19e0682ed446f8397d3a1153642f0
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PLA2R1 KLHL42 DNAH9 DYNC1I1

1.31e-041836343c516fe5083f02bad1f464ed284010b4131a833c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PLA2R1 KLHL42 DNAH9 DYNC1I1

1.31e-041836349c2689d76fc6d30f5ab093428aa669d0a98953cf
ToppCellwk_20-22-Mesenchymal-Chondrocyte-intermediate_chondrocyte|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

GPR137B CRISPLD1 DNAH14 FBXO2

1.31e-041836341464b5c4425e8776c4aeb4d2b560481d4bf13931
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPTA1 LRP2 UNC13C DNAH9

1.34e-041846342cbed6462fea2622871bb7e49b0df3d984239281
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-3|TCGA-Lung / Sample_Type by Project: Shred V9

PLA2R1 CACNA2D1 KLHL42 DYNC1I1

1.34e-04184634ea4ccebe2d54279fcc517e4f0bfa652b91a808bb
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPTA1 LRP2 UNC13C DNAH9

1.34e-04184634ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPTA1 LRP2 UNC13C DNAH9

1.34e-041846342b19a8c5f823e00812908b23e66bb4e563278aff
ToppCelldroplet-Liver-LIVER_HEP-30m-Mesenchymal|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA2D1 MRC2 ASTN2 MMP17

1.36e-04185634f814ec9d4ade717a0109398e9768d0d66f09317b
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKT3 NMT2 UNC13C DYNC1I1

1.36e-04185634cdd75abdaa1ecedfd2e636203b83a6ac1782f0c3
ToppCelldroplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA2D1 MRC2 ASTN2 MMP17

1.36e-0418563440e958511790e84321da5ccf735f9974c06a0263
ToppCelldroplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA2D1 MRC2 ASTN2 MMP17

1.36e-041856345f2eeba80aff145e85cfd81e2890a155406badb9
ToppCellsystemic_lupus_erythematosus-flare-Hematopoietic-progenitor_cell|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SPTA1 NOX3 TM4SF1 CRISPLD1

1.39e-04186634ffd4510b4435d9bf94c2ef14c629f73ab78c5d93
ToppCellEpithelial-Epithelial-D_(Ciliated)|Epithelial / shred on cell class and cell subclass (v4)

RPGRIP1L CCDC180 TM4SF1 DNAH9

1.45e-041886348f30535a32968a81a304315a49c0d90a77d36948
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PLA2R1 MRC2 KLHL42 DYNC1I1

1.45e-041886349db778c1d9e622a68337212296e3a1ed8f771fa5
ToppCellsystemic_lupus_erythematosus-flare-Hematopoietic-progenitor_cell-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SPTA1 NOX3 TM4SF1 CRISPLD1

1.45e-04188634c613c6c7b6de8ed514253c9f9b8622c56fcc1452
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PLA2R1 MRC2 KLHL42 DYNC1I1

1.45e-04188634047c4e0b03fc8334e38c48977e41d26dbe229d47
ToppCellCOVID-19_Severe-HSPC|COVID-19_Severe / disease group, cell group and cell class

ACSM3 TM4SF1 CRISPLD1 DNAH14

1.48e-0418963496015439971e2e5b8d6294ca5a6b873c7774e925
ToppCelldroplet-Lung-18m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PLA2R1 MRC2 SCN3A ASTN2

1.54e-0419163436467322096bc766cd777dae3bfb4e65511e492c
ToppCelldroplet-Lung-18m-Mesenchymal-fibroblast-alveolar_fibroblast|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PLA2R1 MRC2 SCN3A ASTN2

1.54e-0419163494795daf05061baa3b72a1b01c9e940af86de044
ToppCelldroplet-Lung-30m-Mesenchymal-fibroblast|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PLA2R1 MRC2 SCN3A ASTN2

1.54e-04191634cd497abed9e00e4e0becd9dbc036c6e7a60ae791
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PLA2R1 CACNA2D1 MRC2 SCN3A

1.54e-04191634c715bbdbbf1482aad45a50a16d5232fd35a9a0bb
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast-alveolar_fibroblast|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PLA2R1 CACNA2D1 MRC2 SCN3A

1.54e-04191634243d83cbfcc4996ad087ec6386e559e0b8662004
ToppCellCiliated-cil-3|World / Class top

RPGRIP1L CCDC180 TM4SF1 DNAH9

1.57e-041926344989ebb8812b8af1870599acd932849122c05a29
ToppCelldroplet-Lung-30m-Mesenchymal|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PLA2R1 CACNA2D1 MRC2 SCN3A

1.57e-041926345d5bec238b196f0b3e727fd94f078d6ae524cb01
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GABRR2 DCHS2 SPTA1 MMP17

1.60e-04193634315840bc48899f3a36d57b19197509de19716e3d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ATP6V0A4 LRP2 ASTN2 DNAH14

1.60e-0419363482e8a4c40299ffcdfd5a0da711bb9de6fb8a2eaa
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ATP6V0A4 LRP2 ASTN2 DNAH14

1.60e-041936343866667dd221612589ae50f5c52f73a183a49ce6
ToppCellLA|World / Chamber and Cluster_Paper

AKT3 ACSM3 MRC2 LRP2

1.60e-04193634d4bf89437216baf489ea0239136dcedf3b6714af
ToppCellMegakaryocytic-erythropoietic|World / Lineage, cell class and subclass

MRC2 SPTA1 PGRMC1 DCAF12

1.60e-04193634805c2e2e5d8a9df5ce796d5c0206d6493ab53c88
ToppCellMesenchymal-matrix_fibroblast_1_cell|World / Lineage, Cell type, age group and donor

CACNA1C CACNA2D1 MRC2 UNC13C

1.60e-04193634acad568621ed677031797b8c2e34dafea798d681
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CACNA1C CACNA2D1 MRC2 UNC13C

1.64e-0419463435f132cc38ac133be01834ed0946188aa0757eb4
ToppCell(4)_Endothelial_cells-(4)_Lymph_vessel|(4)_Endothelial_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

SCN3A ACSM5 DYNC1I1 FBXO2

1.64e-041946349735b86d3b2480a0b34d8aab8e7bd609d83c2454
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CACNA2D1 MRC2 UNC13C DYNC1I1

1.67e-041956341cdf5f296029ae424d9dba42e86a6d111e4896e6
ToppCellCOVID-19-Fibroblasts-Intermediate_pathological_FB|COVID-19 / group, cell type (main and fine annotations)

CACNA1C PLA2R1 CACNA2D1 MRC2

1.74e-04197634f1c8936986123a3151140c374fcd62d6705c530b
ToppCellCOVID-19-lung-Fibroblast|lung / Disease (COVID-19 only), tissue and cell type

CACNA1C PLA2R1 CACNA2D1 MRC2

1.77e-04198634df3de77216f5c5d6141ec44d01c56b942f611838
ToppCelldroplet-Limb_Muscle-nan-3m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA2D1 MRC2 ATP6V0A4 CRISPLD1

1.80e-04199634edd5300da1a3b758210ff8f949e9d1988b8bc7e2
ToppCellcontrol-unassigned|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SCRN3 ACSM3 CCDC180 DCAF12

1.80e-0419963450e2da35edff1aadef939cfbd4549f73c1a07717
ToppCellTracheal-NucSeq-Stromal-Chondrocytic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

AKT3 CRISPLD1 DYNC1I1 FBXO2

1.84e-04200634b5a54b9baf79aea01f76a161f0a39bbe87eb4945
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_perichondrial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1C AKT3 CRISPLD1 DYNC1I1

1.84e-04200634a4ec0e80f5422b91b85264a9bb74568dd577e285
ToppCellTracheal-NucSeq-Stromal-Chondrocytic-Chondrocyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

AKT3 CRISPLD1 DYNC1I1 FBXO2

1.84e-04200634f5bd0b30e478dac09f68c46b0781f5f2e7e3c693
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Neuroepithelial|GW16 / Sample Type, Dataset, Time_group, and Cell type.

PLA2R1 MRC2 TLR4 APOBEC3G

1.84e-0420063425f4c051c2e869481f33c22ad54de97efac444ad
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Neuroepithelial-Proteoglycan-expressing_cell|GW16 / Sample Type, Dataset, Time_group, and Cell type.

PLA2R1 MRC2 TLR4 APOBEC3G

1.84e-04200634da45a85a4667965b24ba824af871157af5b4cd19
ToppCellSepsis-ICU-NoSEP-Lymphocyte-T/NK-NK_CD56bright|ICU-NoSEP / Disease, condition lineage and cell class

MRPS31 NUP107 NMT2 DNAH14

1.84e-04200634c2df917900872453ea17a39928e39d071a6d3339
DiseaseC-type mannose receptor 2 measurement

MRC2 EFCAB3

2.52e-054612EFO_0020204
DiseaseEndometrial Stromal Sarcoma

NUTM2B NUTM2A

4.19e-055612C0206630
DiseaseClear cell sarcoma of kidney

NUTM2E NUTM2B

6.27e-056612C0334488
Diseasegrapefruit juice consumption measurement

CACNA1C DCP1B

8.77e-057612EFO_0010094
Diseasetoll-like receptor 4:Lymphocyte antigen 96 complex measurement

TLR4 ASTN2

8.77e-057612EFO_0008301
DiseaseX-17676 measurement

ACSM3 ACSM5

1.17e-048612EFO_0800785
Diseaseoverall survival, pancreatic carcinoma

CACNA1C DCP1B ASTN2

1.45e-0449613EFO_0000638, EFO_0002618
DiseaseShortened QT interval

CACNA1C CACNA2D1

2.28e-0411612C0151879
DiseaseProteinuria

LRP2 UNC13C

4.34e-0415612HP_0000093
Diseasenucleotide measurement

AKT3 APTX UNC13C

4.72e-0473613EFO_0010513
Diseasecholesteatoma of middle ear (is_marker_for)

TLR4 MMP1

4.95e-0416612DOID:10964 (is_marker_for)
Diseasespinal stenosis

ASTN2 DYNC1I1

5.60e-0417612EFO_0007490
DiseaseHypertensive disease

CACNA1C PTPN1 CACNA2D1 TLR4

6.53e-04190614C0020538
Diseasealpha-tocopherol measurement

CACNA2D1 SCN3A

7.80e-0420612EFO_0007898
Diseasecarotid artery disease (is_implicated_in)

TLR4 MMP1

9.46e-0422612DOID:3407 (is_implicated_in)
Diseaseprimary open angle glaucoma (is_implicated_in)

TLR4 MMP1

1.03e-0323612DOID:1070 (is_implicated_in)
DiseaseBrugada Syndrome (disorder)

CACNA1C CACNA2D1

1.13e-0324612C1142166
DiseaseCardiac Arrhythmia

CACNA1C CACNA2D1

1.22e-0325612C0003811
Diseaseresponse to gemcitabine

CACNA1C DCP1B

1.22e-0325612GO_0036272
Diseasearteriosclerosis (is_implicated_in)

TLR4 MMP1

1.88e-0331612DOID:2349 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
EFQHCWSKFVYSQRE

APOBEC3G

156

Q9HC16
YCWNTFVENHERTFK

AICDA

146

Q9GZX7
KHWNSFNTEYFLESQ

APTX

291

Q7Z2E3
QDDHNWKSEFYANEA

ACOT2

386

P49753
EYFNFAHDVLDVWSR

ACSM5

51

Q6NUN0
TEWQSSHLFKYFQEV

CCDC180

511

Q9P1Z9
NSHYEKFGDFVWRSE

ASTN2

1241

O75129
RHSFFSGVNWQDVYD

AKT3

401

Q9Y243
RAYLEAHETFNEWFK

NUP107

751

P57740
WAAIYQDIRHEASDF

PTPN1

16

P18031
IDEAAKHRYQFWDTQ

NMT2

111

O60551
YDSAFSAAHEEQWKL

RPGRIP1L

366

Q68CZ1
QDNFREFYDSWHSKS

MTMR12

606

Q9C0I1
FEKHSENFAWTENRY

GPBP1

26

Q86WP2
ANLSFNRQFYDEHWS

DYNC1I1

271

O14576
KPHVWTVDYNNSEEF

MGAT5B

591

Q3V5L5
HDESVKKYFASSFEW

FBXO2

161

Q9UK22
SRFLVHFDNWDDTYD

L3MBTL1

441

Q9Y468
ETLSDWESQFTFKYH

PGRMC1

151

O00264
FKDSGWYQVNHSAAE

LMLN2

416

A0A1B0GTW7
EYKFFEHHSTWAQAQ

MRC2

836

Q9UBG0
WVDAYFDKIEHSTFD

LRP2

886

P98164
FNYNEHEVSKRWTFE

PRPF39

321

Q86UA1
QEWEHTSNFDRMIFY

NUTM1

266

Q86Y26
YHEFWFEEATNLATK

THAP12

531

O43422
FSNIDHDWTRENTYV

DCHS2

2571

Q6V1P9
YTFGHRANEWEKTDV

DCP1B

41

Q8IZD4
SETNHYFCDAWNTFD

CACNA1C

1321

Q13936
HQWREDFASNEVVYY

CACNA2D1

111

P54289
LNHDETWRNYFSDID

DCAF12

401

Q5T6F0
TFHVQSWYDEVKDFS

CRISPLD1

131

Q9H336
HAQTLEKYSWEAFDS

F8A1;

291

P23610
NYIFFKAKWETSFNH

SERPINA5

201

P05154
SAYHERKFWFSNRQE

DPY19L4

71

Q7Z388
YQFSLDWFHQVFVSS

DNAH14

2731

Q0VDD8
HTYFKENQEVKEWDF

DNAH9

416

Q9NYC9
FEDYFFHKRDWKTQA

EFCAB3

276

Q8N7B9
HYWKDERLAFSSASN

GABRR2

106

P28476
EWQHTSNFDRMIFYE

NUTM2A

386

Q8IVF1
EWQHTSNFDRMIFYE

NUTM2B

386

A6NNL0
EWQHTSNFDRMIFYE

NUTM2E

386

B1AL46
SQNKSVHSFDYDWYN

GPR137B

261

O60478
EHIEWFRNYFNEKKD

MRPS31

371

Q92665
YERWRSASNHSEMFF

PHF2

281

O75151
IDAAFSWAHNDRTYF

MMP17

431

Q9ULZ9
SWAHNDRTYFFKDQL

MMP17

436

Q9ULZ9
HFDEDERWTNNFREY

MMP1

196

P03956
SYHNSFLIADRNEAW

SCRN3

151

Q0VDG4
STFNWKDYIGDDSHF

SCN3A

311

Q9NY46
FFNLERYHWSQSEEA

NOX3

121

Q9HBY0
DAEYLFHTFASEWLN

PLA2R1

821

Q13018
EYFNFAKDVLDQWTD

ACSM3

56

Q53FZ2
QFYYRDEFSHQVQEW

SUPT6H

691

Q7KZ85
VWDEKFYFECHNSTD

UNC13C

1266

Q8NB66
SSVQRDDFHWEEYLK

SCML2

26

Q9UQR0
FYVFKAEDAHSAQKW

FGD6

1406

Q6ZV73
DTFFDHFNRVQWAFS

SGMS1

171

Q86VZ5
DDYAFQEFNWKADVV

SPTA1

1926

P02549
KYASENHLSRFVWFF

TM4SF1

36

P30408
KTDNEIWNTFFHGRY

ATP6V0A4

436

Q9HBG4
LDQYREFDSLHWFQS

WASHC4

1061

Q2M389
EFDSLHWFQSVREKY

WASHC4

1066

Q2M389
WFKDNYNADFLEDRQ

SNX16

171

P57768
ERVKDFSYNFGWQHL

TLR4

321

O00206
KDSGQWHYFDDNSVS

USP11

896

P51784
FKDVSVDFTQEEWYH

ZFP90

16

Q8TF47
HRVFLKYNIFSDSWE

KLHL42

466

Q9P2K6