Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	protein kinase binding	TRADD NBEAL1 KIZ ZBTB4 FRS2 DAXX DELE1 RAD54L2 TRIM22 RYR2 SLC12A5 AKT1 PLCB4 MAP3K13 MAP3K7 UTRN EPHA1 DNM2	1.65e-04	873	156	18	GO:0019901
GeneOntologyMolecularFunction	linear polyubiquitin binding	RNF31 MAP3K7	1.81e-04	3	156	2	GO:1990450
GeneOntologyBiologicalProcess	cell-substrate adhesion	OTOA ITGA11 TEK RADIL TNN LRP1 STRC UTRN TBCD EPHA1 STRCP1 DNM2 FERMT3	1.49e-05	410	156	13	GO:0031589
GeneOntologyCellularComponent	9+2 non-motile cilium	DCDC2 STRC STRCP1	1.40e-04	14	156	3	GO:0097732
GeneOntologyCellularComponent	kinocilium	DCDC2 STRC STRCP1	1.40e-04	14	156	3	GO:0060091
Domain	LRR_8	LRRC37A3 LRRC37A2 LRRC70 TLR9 LRIG3 LRRC37A PRELP LRRC53 SLIT1 TLR5	1.76e-06	171	156	10	PF13855
Domain	LRRC37AB_C	LRRC37A3 LRRC37A2 LRRC37A	2.27e-06	4	156	3	IPR029423
Domain	LRRC37AB_C	LRRC37A3 LRRC37A2 LRRC37A	2.27e-06	4	156	3	PF14914
Domain	LRRC37_N	LRRC37A3 LRRC37A2 LRRC37A	2.27e-06	4	156	3	IPR032754
Domain	LRRC37	LRRC37A3 LRRC37A2 LRRC37A	2.27e-06	4	156	3	PF15779
Domain	LRRC37A/B-like	LRRC37A3 LRRC37A2 LRRC37A	2.27e-06	4	156	3	IPR015753
Domain	LRR_TYP	LRRC37A3 LRRC37A2 LRRC70 TLR9 LRIG3 LRRC37A PRELP LRRC53 SLIT1 TLR5	2.41e-06	177	156	10	SM00369
Domain	Leu-rich_rpt_typical-subtyp	LRRC37A3 LRRC37A2 LRRC70 TLR9 LRIG3 LRRC37A PRELP LRRC53 SLIT1 TLR5	2.41e-06	177	156	10	IPR003591
Domain	LRR	LRRC37A3 LRRC37A2 LRRC70 TLR9 LRIG3 LRRC37A PRELP LRRC53 SLIT1 TLR5	7.48e-06	201	156	10	PS51450
Domain	LRR_1	LRRC45 LRRC37A3 LRRC37A2 LRRC70 TLR9 LRIG3 LRRC37A PRELP SLIT1 TLR5	1.58e-05	219	156	10	PF00560
Domain	Leu-rich_rpt	LRRC45 LRRC37A3 LRRC37A2 LRRC70 TLR9 LRIG3 LRRC37A PRELP LRRC53 SLIT1 TLR5	1.78e-05	271	156	11	IPR001611
Domain	Kinase-like_dom	ANKK1 RPS6KA4 SPEG PAK4 SIK3 TEK ACAD11 PI4KA AKT1 MAP3K15 MAP3K13 EIF2AK1 MAP3K7 EPHA1 DNM2	5.04e-05	542	156	15	IPR011009
Domain	-	ASF1B ASF1A	6.93e-05	2	156	2	2.60.40.1490
Domain	ASF1_hist_chap	ASF1B ASF1A	6.93e-05	2	156	2	PF04729
Domain	DUF4685	KIAA1614 C9orf50	6.93e-05	2	156	2	IPR032756
Domain	DUF4685	KIAA1614 C9orf50	6.93e-05	2	156	2	PF15737
Domain	Gamma_tubulin	TUBG2 TUBG1	6.93e-05	2	156	2	IPR002454
Domain	ASF1-like	ASF1B ASF1A	6.93e-05	2	156	2	IPR006818
Domain	-	LRRC45 LRRC37A3 LRRC37A2 LRRC70 TLR9 LRIG3 LRRC37A PRELP LRRC53 SLIT1 TLR5	8.29e-05	321	156	11	3.80.10.10
Domain	Ank_2	ANKK1 ACAP1 ANKMY1 ANKRD27 ANKRD44 ASB18 ASB16 ASB10 MIB1	8.30e-05	215	156	9	PF12796
Domain	L_dom-like	LRRC45 LRRC37A3 LRRC37A2 LRRC70 TLR9 LRIG3 LRRC37A PRELP LRRC53 SLIT1 TLR5	1.00e-04	328	156	11	IPR032675
Domain	Ank	ANKK1 ACAP1 ANKMY1 ANKRD27 ANKRD44 ASB18 ASB16 ASB10 MIB1	1.30e-04	228	156	9	PF00023
Domain	Stereocilin-rel	OTOA STRC	2.07e-04	3	156	2	IPR026664
Domain	S_TKc	ANKK1 RPS6KA4 SPEG PAK4 SIK3 TEK AKT1 MAP3K15 MAP3K13 EIF2AK1 MAP3K7	2.21e-04	359	156	11	SM00220
Domain	-	TIFAB RADIL STARD9 CHFR	2.24e-04	36	156	4	2.60.200.20
Domain	FHA_dom	TIFAB RADIL STARD9 CHFR	2.24e-04	36	156	4	IPR000253
Domain	-	ANKK1 ACAP1 ANKMY1 ANKRD27 ANKRD44 ASB18 ASB16 ASB10 MIB1	2.43e-04	248	156	9	1.25.40.20
Domain	ANK	ANKK1 ACAP1 ANKMY1 ANKRD27 ANKRD44 ASB18 ASB16 ASB10 MIB1	2.66e-04	251	156	9	SM00248
Domain	ANK_REPEAT	ANKK1 ACAP1 ANKMY1 ANKRD27 ANKRD44 ASB18 ASB16 ASB10 MIB1	2.82e-04	253	156	9	PS50088
Domain	Ankyrin_rpt-contain_dom	ANKK1 ACAP1 ANKMY1 ANKRD27 ANKRD44 ASB18 ASB16 ASB10 MIB1	2.90e-04	254	156	9	IPR020683
Domain	ANK_REP_REGION	ANKK1 ACAP1 ANKMY1 ANKRD27 ANKRD44 ASB18 ASB16 ASB10 MIB1	2.90e-04	254	156	9	PS50297
Domain	Growth_fac_rcpt_	TEK IGFBP6 TNN SLIT1 DLL3 LRP1 EPHA1	3.41e-04	156	156	7	IPR009030
Domain	Ankyrin_rpt	ANKK1 ACAP1 ANKMY1 ANKRD27 ANKRD44 ASB18 ASB16 ASB10 MIB1	3.64e-04	262	156	9	IPR002110
Domain	HSA	EP400 SRCAP	4.11e-04	4	156	2	SM00573
Domain	HSA	EP400 SRCAP	4.11e-04	4	156	2	PS51204
Domain	HSA_dom	EP400 SRCAP	4.11e-04	4	156	2	IPR014012
Domain	HSA	EP400 SRCAP	4.11e-04	4	156	2	PF07529
Domain	PROTEIN_KINASE_ATP	ANKK1 RPS6KA4 SPEG PAK4 SIK3 TEK AKT1 MAP3K15 MAP3K13 EIF2AK1 MAP3K7 EPHA1	4.85e-04	459	156	12	PS00107
Domain	ConA-like_dom	NBEAL1 TRIM35 TRIM49D1 TRIM22 PTPRT RYR2 SLIT1 WDFY3	5.17e-04	219	156	8	IPR013320
Domain	TIR	TLR9 IL1RL2 TLR5	6.81e-04	21	156	3	SM00255
Domain	DUF4704	NBEAL1 WDFY3	6.82e-04	5	156	2	IPR031570
Domain	DUF4704	NBEAL1 WDFY3	6.82e-04	5	156	2	PF15787
Domain	TIR	TLR9 IL1RL2 TLR5	7.83e-04	22	156	3	PF01582
Domain	Prot_kinase_dom	ANKK1 RPS6KA4 SPEG PAK4 SIK3 TEK AKT1 MAP3K15 MAP3K13 EIF2AK1 MAP3K7 EPHA1	8.46e-04	489	156	12	IPR000719
Domain	Ser/Thr_kinase_AS	ANKK1 RPS6KA4 SPEG PAK4 SIK3 AKT1 MAP3K15 MAP3K13 EIF2AK1 MAP3K7	8.54e-04	357	156	10	IPR008271
Domain	-	TLR9 IL1RL2 TLR5	8.95e-04	23	156	3	3.40.50.10140
Domain	PROTEIN_KINASE_DOM	ANKK1 RPS6KA4 SPEG PAK4 SIK3 TEK AKT1 MAP3K15 MAP3K13 EIF2AK1 MAP3K7 EPHA1	9.07e-04	493	156	12	PS50011
Domain	PH_dom-like	ACAP1 NBEAL1 FRS2 PLEKHG2 MTMR3 AKT1 VAV3 PLCB4 WDFY3 DNM2 FERMT3	9.23e-04	426	156	11	IPR011993
Domain	SMAD_FHA_domain	TIFAB RADIL STARD9 CHFR	9.28e-04	52	156	4	IPR008984
Domain	PROTEIN_KINASE_ST	ANKK1 RPS6KA4 SPEG PAK4 SIK3 AKT1 MAP3K15 MAP3K13 EIF2AK1 MAP3K7	9.49e-04	362	156	10	PS00108
Domain	TIR	TLR9 IL1RL2 TLR5	1.02e-03	24	156	3	PS50104
Domain	PH_BEACH	NBEAL1 WDFY3	1.02e-03	6	156	2	PF14844
Domain	TIR_dom	TLR9 IL1RL2 TLR5	1.15e-03	25	156	3	IPR000157
Domain	Protein_kinase_ATP_BS	RPS6KA4 SPEG PAK4 SIK3 TEK AKT1 MAP3K15 EIF2AK1 MAP3K7 EPHA1	1.34e-03	379	156	10	IPR017441
Domain	Pkinase	ANKK1 RPS6KA4 SPEG PAK4 SIK3 AKT1 MAP3K15 MAP3K13 EIF2AK1 MAP3K7	1.39e-03	381	156	10	PF00069
Domain	DHC_N1	DNAH9 DYNC1H1	1.88e-03	8	156	2	PF08385
Domain	PH-BEACH_dom	NBEAL1 WDFY3	1.88e-03	8	156	2	IPR023362
Domain	-	NBEAL1 WDFY3	1.88e-03	8	156	2	2.30.29.40
Domain	PH_BEACH	NBEAL1 WDFY3	1.88e-03	8	156	2	PS51783
Domain	Dynein_heavy_dom-1	DNAH9 DYNC1H1	1.88e-03	8	156	2	IPR013594
Domain	FHA_DOMAIN	TIFAB RADIL CHFR	2.16e-03	31	156	3	PS50006
Domain	FHA	TIFAB STARD9 CHFR	2.16e-03	31	156	3	PF00498
Domain	SNF2_N	EP400 RAD54L2 SRCAP	2.37e-03	32	156	3	IPR000330
Domain	SNF2_N	EP400 RAD54L2 SRCAP	2.37e-03	32	156	3	PF00176
Domain	LRRCT	LRIG3 SLIT1 TLR5	2.37e-03	32	156	3	PF01463
Domain	BEACH	NBEAL1 WDFY3	2.40e-03	9	156	2	PS50197
Domain	Beach	NBEAL1 WDFY3	2.40e-03	9	156	2	PF02138
Domain	-	NBEAL1 WDFY3	2.40e-03	9	156	2	1.10.1540.10
Domain	Beach	NBEAL1 WDFY3	2.40e-03	9	156	2	SM01026
Domain	BEACH_dom	NBEAL1 WDFY3	2.40e-03	9	156	2	IPR000409
Domain	Ank_3	ANKRD27 ASB18	2.99e-03	10	156	2	PF13606
Domain	SOCS_box	ASB18 ASB16 ASB10	3.89e-03	38	156	3	PF07525
Domain	SOCS_box	ASB18 ASB16 ASB10	4.19e-03	39	156	3	SM00969
Domain	SOCS_box	ASB18 ASB16 ASB10	4.19e-03	39	156	3	IPR001496
Domain	SOCS	ASB18 ASB16 ASB10	4.19e-03	39	156	3	PS50225
Domain	Peptidase_M1	ANPEP RNPEPL1	4.33e-03	12	156	2	IPR001930
Domain	Pkinase_Tyr	ANKK1 TEK MAP3K13 MAP3K7 EPHA1	4.57e-03	129	156	5	PF07714
Domain	Peptidase_M1_N	ANPEP RNPEPL1	5.09e-03	13	156	2	IPR014782
Domain	Peptidase_M1	ANPEP RNPEPL1	5.09e-03	13	156	2	PF01433
Domain	-	ACAP1 FRS2 PLEKHG2 MTMR3 AKT1 VAV3 PLCB4 DNM2 FERMT3	5.66e-03	391	156	9	2.30.29.30
Domain	Dynein_heavy_chain_D4_dom	DNAH9 DYNC1H1	5.91e-03	14	156	2	IPR024317
Domain	Dynein_HC_stalk	DNAH9 DYNC1H1	5.91e-03	14	156	2	IPR024743
Domain	Dynein_heavy_dom-2	DNAH9 DYNC1H1	5.91e-03	14	156	2	IPR013602
Domain	DHC_N2	DNAH9 DYNC1H1	5.91e-03	14	156	2	PF08393
Domain	ATPase_dyneun-rel_AAA	DNAH9 DYNC1H1	5.91e-03	14	156	2	IPR011704
Domain	MT	DNAH9 DYNC1H1	5.91e-03	14	156	2	PF12777
Domain	AAA_8	DNAH9 DYNC1H1	5.91e-03	14	156	2	PF12780
Domain	AAA_5	DNAH9 DYNC1H1	5.91e-03	14	156	2	PF07728
Domain	Ser-Thr/Tyr_kinase_cat_dom	ANKK1 TEK MAP3K13 MAP3K7 EPHA1	6.07e-03	138	156	5	IPR001245
Domain	SPRY	TRIM35 TRIM49D1 TRIM22 RYR2	6.09e-03	87	156	4	SM00449
Domain	DHC_fam	DNAH9 DYNC1H1	6.78e-03	15	156	2	IPR026983
Domain	Dynein_heavy	DNAH9 DYNC1H1	6.78e-03	15	156	2	PF03028
Domain	Dynein_heavy_dom	DNAH9 DYNC1H1	6.78e-03	15	156	2	IPR004273
Domain	Cys-rich_flank_reg_C	LRRC70 LRIG3 SLIT1 TLR5	6.86e-03	90	156	4	IPR000483
Domain	LRRCT	LRRC70 LRIG3 SLIT1 TLR5	6.86e-03	90	156	4	SM00082
Domain	SPRY	TRIM35 TRIM49D1 TRIM22 RYR2	7.98e-03	94	156	4	PF00622
Domain	SPRY_dom	TRIM35 TRIM49D1 TRIM22 RYR2	7.98e-03	94	156	4	IPR003877
Domain	B30.2/SPRY	TRIM35 TRIM49D1 TRIM22 RYR2	8.28e-03	95	156	4	IPR001870
Domain	B302_SPRY	TRIM35 TRIM49D1 TRIM22 RYR2	8.28e-03	95	156	4	PS50188
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	ANKRD13D EP400 ATP13A1 SPEG RNPEPL1 ZBTB4 PLXND1 SRCAP EIF6 TUBG1 ANO8 PHC2 KCNH3 RADIL RPAP1 PI4KA MTMR3 NINL AKT1 WDFY3 DYNC1H1 TBCD	1.51e-08	1105	165	22	35748872
Pubmed	Primate segmental duplication creates novel promoters for the LRRC37 gene family within the 17q21.31 inversion polymorphism region.	LRRC37A3 LRRC37A2 LRRC37A	4.18e-07	4	165	3	22419166
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	SATB2 LRRC37A3 ORC3 CDS2 LRRC70 SIK3 RYR2 EXD3 SALL1 ACAD11 PRELP MIB1 WDFY3 KDM6A DNM2	4.39e-07	638	165	15	31182584
Pubmed	Mapping a dynamic innate immunity protein interaction network regulating type I interferon production.	RNF31 ORC3 COG7 TLR9 EIF6 STAT2 ACAD11 MIB1 EBNA1BP2 MAP3K7	1.12e-06	283	165	10	21903422
Pubmed	CROCCP2 acts as a human-specific modifier of cilia dynamics and mTOR signaling to promote expansion of cortical progenitors.	TUBG2 TUBG1 CROCC	2.08e-06	6	165	3	36334595
Pubmed	WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.	EP400 ORC3 DAXX SRCAP EIF6 TUBG1 PHC2 ANAPC1 EBNA1BP2 UTRN DNM2	3.18e-06	394	165	11	27248496
Pubmed	A Cul4 E3 ubiquitin ligase regulates histone hand-off during nucleosome assembly.	DAXX ASF1B ASF1A	5.77e-06	8	165	3	24209620
Pubmed	Functional analysis of bacterial artificial chromosomes in mammalian cells: mouse Cdc6 is associated with the mitotic spindle apparatus.	TUBG2 TUBG1 TFDP1	8.63e-06	9	165	3	14667810
Pubmed	TUBG1 missense variants underlying cortical malformations disrupt neuronal locomotion and microtubule dynamics but not neurogenesis.	SATB2 TUBG2 TUBG1	8.63e-06	9	165	3	31086189
Pubmed	Evolutionary dynamism of the primate LRRC37 gene family.	LRRC37A3 LRRC37A2 LRRC37A	1.23e-05	10	165	3	23064749
Pubmed	Eml1 loss impairs apical progenitor spindle length and soma shape in the developing cerebral cortex.	TUBG2 TUBG1 DYNC1H1	1.68e-05	11	165	3	29229923
Pubmed	P21-Activated Kinase 4 Pak4 Maintains Embryonic Stem Cell Pluripotency via Akt Activation.	PAK4 AKT1	2.24e-05	2	165	2	35896382
Pubmed	Distinct role of histone chaperone Asf1a and Asf1b during fertilization and pre-implantation embryonic development in mice.	ASF1B ASF1A	2.24e-05	2	165	2	34906203
Pubmed	A PKB-SPEG signaling nexus links insulin resistance with diabetic cardiomyopathy by regulating calcium homeostasis.	SPEG AKT1	2.24e-05	2	165	2	32367034
Pubmed	Srcap haploinsufficiency induced autistic-like behaviors in mice through disruption of Satb2 expression.	SATB2 SRCAP	2.24e-05	2	165	2	38733588
Pubmed	MTOC reorientation occurs during FcgammaR-mediated phagocytosis in macrophages.	TUBG2 TUBG1	2.24e-05	2	165	2	17442887
Pubmed	Myogenic Akt signaling upregulates the utrophin-glycoprotein complex and promotes sarcolemma stability in muscular dystrophy.	AKT1 UTRN	2.24e-05	2	165	2	18986978
Pubmed	Overexpression of γ-tubulin in non-small cell lung cancer.	TUBG2 TUBG1	2.24e-05	2	165	2	22806905
Pubmed	Frequency of the STRC-CATSPER2 deletion in STRC-associated hearing loss patients.	CATSPER2 STRC	2.24e-05	2	165	2	35022556
Pubmed	Expression of Ang-2/Tie-2 and PI3K/AKT in colorectal cancer.	TEK AKT1	2.24e-05	2	165	2	25374184
Pubmed	The catalytic subunit of the SWR1 remodeler is a histone chaperone for the H2A.Z-H2B dimer.	EP400 SRCAP	2.24e-05	2	165	2	24507717
Pubmed	Loss of SPEG Inhibitory Phosphorylation of Ryanodine Receptor Type-2 Promotes Atrial Fibrillation.	SPEG RYR2	2.24e-05	2	165	2	32683896
Pubmed	Dual-vector gene therapy restores cochlear amplification and auditory sensitivity in a mouse model of DFNB16 hearing loss.	STRC STRCP1	2.24e-05	2	165	2	34910522
Pubmed	Regulation of replication fork progression through histone supply and demand.	ASF1B ASF1A	2.24e-05	2	165	2	18096807
Pubmed	Aggregated low-density lipoprotein induces LRP1 stabilization through E3 ubiquitin ligase CHFR downregulation in human vascular smooth muscle cells.	CHFR LRP1	2.24e-05	2	165	2	23241409
Pubmed	Association study of Toll-like receptor 5 (TLR5) and Toll-like receptor 9 (TLR9) polymorphisms in systemic lupus erythematosus.	TLR9 TLR5	2.24e-05	2	165	2	17516623
Pubmed	Relevant genetic polymorphisms and kidney expression of Toll-like receptor (TLR)-5 and TLR-9 in lupus nephritis.	TLR9 TLR5	2.24e-05	2	165	2	28763101
Pubmed	Allocation of gamma-tubulin between oocyte cortex and meiotic spindle influences asymmetric cytokinesis in the mouse oocyte.	TUBG2 TUBG1	2.24e-05	2	165	2	17287496
Pubmed	DELE1 oligomerization promotes integrated stress response activation.	DELE1 EIF2AK1	2.24e-05	2	165	2	37550454
Pubmed	STRC-Related Autosomal Recessive Hearing Loss	CATSPER2 STRC	2.24e-05	2	165	2	38109326
Pubmed	Differential expression of human γ-tubulin isotypes during neuronal development and oxidative stress points to a γ-tubulin-2 prosurvival function.	TUBG2 TUBG1	2.24e-05	2	165	2	28119396
Pubmed	Elevated expression of ASF1B correlates with poor prognosis in human lung adenocarcinoma.	ASF1B ASF1A	2.24e-05	2	165	2	33576264
Pubmed	Quantitative and electron microscopic studies of sensory ganglion cells of the Sprawling mouse.	GPI DYNC1H1	2.24e-05	2	165	2	894335
Pubmed	MTMR3 risk alleles enhance Toll Like Receptor 9-induced IgA immunity in IgA nephropathy.	TLR9 MTMR3	2.24e-05	2	165	2	37414396
Pubmed	Mutations in a new gene encoding a protein of the hair bundle cause non-syndromic deafness at the DFNB16 locus.	STRC STRCP1	2.24e-05	2	165	2	11687802
Pubmed	Polymorphisms in TLR9 but not in TLR5 increase the risk for duodenal ulcer and alter cytokine expression in the gastric mucosa.	TLR9 TLR5	2.24e-05	2	165	2	25995217
Pubmed	Whole genome methylation array reveals the down-regulation of IGFBP6 and SATB2 by HIV-1.	SATB2 IGFBP6	2.24e-05	2	165	2	26039376
Pubmed	Knockdown of anti-silencing function 1B histone chaperone induces cell apoptosis via repressing PI3K/Akt pathway in prostate cancer.	ASF1B AKT1	2.24e-05	2	165	2	30132513
Pubmed	COMP-Ang1 enhances DNA synthesis and cell cycle progression in human periodontal ligament cells via Tie2-mediated phosphorylation of PI3K/Akt and MAPKs.	TEK AKT1	2.24e-05	2	165	2	27107990
Pubmed	Involvement of FKHR-dependent TRADD expression in chemotherapeutic drug-induced apoptosis.	TRADD AKT1	2.24e-05	2	165	2	12446787
Pubmed	PAK4 confers cisplatin resistance in gastric cancer cells via PI3K/Akt- and MEK/ERK-dependent pathways.	PAK4 AKT1	2.24e-05	2	165	2	27919028
Pubmed	Gene knockout analysis of two gamma-tubulin isoforms in mice.	TUBG2 TUBG1	2.24e-05	2	165	2	15893303
Pubmed	Rapid induction of alternative lengthening of telomeres by depletion of the histone chaperone ASF1.	ASF1B ASF1A	2.24e-05	2	165	2	24413054
Pubmed	The Retinal Pigment Epithelium Is a Notch Signaling Niche in the Mouse Retina.	TUBG2 TUBG1 DLL3 MIB1	2.28e-05	35	165	4	28402857
Pubmed	Choroid plexuses carry nodal-like cilia that undergo axoneme regression from early adult stage.	LRRC45 TUBG2 TUBG1 DNAH9	2.28e-05	35	165	4	37890489
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	EP400 SPEG SLC12A5 LRIG3 RPAP1 STARD9 SLIT1 MTMR3 CROCC DYNC1H1	2.70e-05	407	165	10	12693553
Pubmed	Primary cilia are required in a unique subpopulation of neural progenitors.	SATB2 TUBG2 TUBG1	3.67e-05	14	165	3	25114218
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	TUBG2 ATP13A1 ZBTB4 PSMD5 ADAMTS8 RAD54L2 ADARB1 WAC VPS35L MIB1 MTMR3 LRP1 WDFY3 EIF2AK1 UTRN KDM6A DYNC1H1 DNM2	4.25e-05	1285	165	18	35914814
Pubmed	MAP3Ks as central regulators of cell fate during development.	MAP3K15 MAP3K13 MAP3K7	4.58e-05	15	165	3	18855897
Pubmed	Tuba8 Drives Differentiation of Cortical Radial Glia into Apical Intermediate Progenitors by Tuning Modifications of Tubulin C Termini.	SATB2 TUBG2 TUBG1	4.58e-05	15	165	3	32097653
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SATB2 EP400 TRIM35 PAK4 PLXND1 SIK3 KIAA1614 ANKRD27 LRIG3 MIB1 NINL	4.88e-05	529	165	11	14621295
Pubmed	Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.	CAPN14 RPS6KA4 PAK4 ADAMTS8 PLXND1 SIK3 KCNH3 EIF3CL BOK MTMR3 LRP1 AKT1 DNM2	4.95e-05	730	165	13	34857952
Pubmed	A large-scale candidate gene association study of age at menarche and age at natural menopause.	ANKK1 F2 TGFBR3 IGFBP6 EIF2B4 CHFR AKT1 BMP15	5.43e-05	275	165	8	20734064
Pubmed	Prediction of the coding sequences of mouse homologues of FLJ genes: the complete nucleotide sequences of 110 mouse FLJ-homologous cDnas identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	RNF31 PLEKHG2 ANKRD27 FCSK ARMC5	5.46e-05	85	165	5	15449545
Pubmed	Impaired cortical neurogenesis in plexin-B1 and -B2 double deletion mutant.	SATB2 TUBG2 TUBG1	5.61e-05	16	165	3	26579598
Pubmed	Loss of RNA-Binding Protein HuR Leads to Defective Ependymal Cells and Hydrocephalus.	SATB2 TUBG2 TUBG1	5.61e-05	16	165	3	34815315
Pubmed	The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition.	RPS6KA4 EP400 PAK4 SRCAP TUBG1 PHC2 RADIL ANAPC1	6.31e-05	281	165	8	24163370
Pubmed	Akt is a major angiogenic mediator downstream of the Ang1/Tie2 signaling pathway.	TEK AKT1	6.69e-05	3	165	2	15242771
Pubmed	Dynamin-2 reduction rescues the skeletal myopathy of a SPEG-deficient mouse model.	SPEG DNM2	6.69e-05	3	165	2	35763354
Pubmed	Cochlear outer hair cell horizontal top connectors mediate mature stereocilia bundle mechanics.	STRC STRCP1	6.69e-05	3	165	2	30801007
Pubmed	VEGF induces Tie2 shedding via a phosphoinositide 3-kinase/Akt dependent pathway to modulate Tie2 signaling.	TEK AKT1	6.69e-05	3	165	2	17901375
Pubmed	Aurora B interaction of centrosomal Nlp regulates cytokinesis.	TUBG1 NINL	6.69e-05	3	165	2	20864540
Pubmed	Semaphorin 4A enhances lung fibrosis through activation of Akt via PlexinD1 receptor.	PLXND1 AKT1	6.69e-05	3	165	2	26648031
Pubmed	Activation of enteroendocrine cells via TLRs induces hormone, chemokine, and defensin secretion.	TLR9 TLR5	6.69e-05	3	165	2	17371986
Pubmed	Low-density lipoprotein receptor-related protein 1 polymorphism 663 C > T affects clotting factor VIII activity and increases the risk of venous thromboembolism.	F2 LRP1	6.69e-05	3	165	2	17155964
Pubmed	Low density lipoprotein receptor-related protein 1 promotes anti-apoptotic signaling in neurons by activating Akt survival pathway.	LRP1 AKT1	6.69e-05	3	165	2	19815552
Pubmed	Increased Expression of Toll-Like Receptors 4, 5, and 9 in Small Bowel Mucosa from Patients with Irritable Bowel Syndrome.	TLR9 TLR5	6.69e-05	3	165	2	28246611
Pubmed	The gamma-tubulin gene family in humans.	TUBG2 TUBG1	6.69e-05	3	165	2	10903841
Pubmed	The HRI branch of the integrated stress response selectively triggers mitophagy.	DELE1 EIF2AK1	6.69e-05	3	165	2	38340717
Pubmed	Structural plasticity of histones H3-H4 facilitates their allosteric exchange between RbAp48 and ASF1.	ASF1B ASF1A	6.69e-05	3	165	2	23178455
Pubmed	RIF1-ASF1-mediated high-order chromatin structure safeguards genome integrity.	ASF1B ASF1A	6.69e-05	3	165	2	35177609
Pubmed	Human TUBG2 gene is expressed as two splice variant mRNA and involved in cell growth.	TUBG2 TUBG1	6.69e-05	3	165	2	27015882
Pubmed	Loss of TRADD attenuates pressure overload-induced cardiac hypertrophy through regulating TAK1/P38 MAPK signalling in mice.	TRADD MAP3K7	6.69e-05	3	165	2	28013046
Pubmed	The association of variations in TLR genes and spontaneous immune control of hepatitis B virus.	TLR9 TLR5	6.69e-05	3	165	2	29276096
Pubmed	Transcriptional regulation of human chromatin assembly factor ASF1.	ASF1B ASF1A	6.69e-05	3	165	2	17328667
Pubmed	Characterization of the human homologue of the yeast spc98p and its association with gamma-tubulin.	TUBG2 TUBG1	6.69e-05	3	165	2	9566969
Pubmed	Tousled-like kinases phosphorylate Asf1 to promote histone supply during DNA replication.	ASF1B ASF1A	6.69e-05	3	165	2	24598821
Pubmed	In vivo study of the nucleosome assembly functions of ASF1 histone chaperones in human cells.	ASF1B ASF1A	6.69e-05	3	165	2	18378699
Pubmed	Phosphorylation of ACAP1 by Akt regulates the stimulation-dependent recycling of integrin beta1 to control cell migration.	ACAP1 AKT1	6.69e-05	3	165	2	16256741
Pubmed	The Aurora A-HP1γ pathway regulates gene expression and mitosis in cells from the sperm lineage.	TUBG2 TUBG1	6.69e-05	3	165	2	26021315
Pubmed	Downregulation of lncRNA XIST may promote Th17 differentiation through KDM6A-TSAd pathway in neuromyelitis optica spectrum disorders.	SH2D2A KDM6A	6.69e-05	3	165	2	37315471
Pubmed	Tousled-like kinase 2 targets ASF1 histone chaperones through client mimicry.	ASF1B ASF1A	6.69e-05	3	165	2	35136069
Pubmed	The LRP1-independent mechanism of PAI-1-induced migration in CpG-ODN activated macrophages.	TLR9 LRP1	6.69e-05	3	165	2	24440681
Pubmed	TLK1B promotes repair of UV-damaged DNA through chromatin remodeling by Asf1.	ASF1B ASF1A	6.69e-05	3	165	2	17054786
Pubmed	Mouse inscuteable induces apical-basal spindle orientation to facilitate intermediate progenitor generation in the developing neocortex.	SATB2 TUBG2 TUBG1	6.79e-05	17	165	3	22017987
Pubmed	Mammalian Otolin: a multimeric glycoprotein specific to the inner ear that interacts with otoconial matrix protein Otoconin-90 and Cerebellin-1.	OTOA STRC STRCP1	6.79e-05	17	165	3	20856818
Pubmed	O-linked N-acetylglucosamine transferase (OGT) interacts with the histone chaperone HIRA complex and regulates nucleosome assembly and cellular senescence.	DAXX MAP3K7 ASF1A	6.79e-05	17	165	3	27217568
Pubmed	ASB proteins interact with Cullin5 and Rbx2 to form E3 ubiquitin ligase complexes.	ASB18 ASB16 ASB10	6.79e-05	17	165	3	16325183
Pubmed	Cep55 regulation of PI3K/Akt signaling is required for neocortical development and ciliogenesis.	TUBG2 TUBG1 AKT1	6.79e-05	17	165	3	34710087
Pubmed	Modulating TRADD to restore cellular homeostasis and inhibit apoptosis.	TRADD RNF31 MAP3K7	8.12e-05	18	165	3	32968279
Pubmed	Maternal hyperglycemia activates an ASK1-FoxO3a-caspase 8 pathway that leads to embryonic neural tube defects.	TRADD AKT1 MAP3K7	8.12e-05	18	165	3	23982205
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	RNF31 EP400 SIK3 SRCAP TUBG1 TFDP1 INTS10 FCSK LRIG3 ACAD11 ANAPC1 LRP1 RARS2 WDFY3 EBNA1BP2 CKAP4	8.85e-05	1116	165	16	31753913
Pubmed	The death-associated protein DAXX is a novel histone chaperone involved in the replication-independent deposition of H3.3.	DAXX ASF1B ASF1A	9.61e-05	19	165	3	20504901
Pubmed	Mind bomb-1 is essential for intraembryonic hematopoiesis in the aortic endothelium and the subaortic patches.	TEK DLL3 MIB1	9.61e-05	19	165	3	18505817
Pubmed	Cell Metabolic Alterations due to Mcph1 Mutation in Microcephaly.	SATB2 TUBG2 TUBG1	1.13e-04	20	165	3	32294449
Pubmed	Deficient adaptation to centrosome duplication defects in neural progenitors causes microcephaly and subcortical heterotopias.	SATB2 TUBG2 TUBG1	1.13e-04	20	165	3	34237032
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	RPS6KA4 PAK4 PSMD5 SIK3 EIF6 EIF3CL ACAD11 ANAPC1 AKT1 VAV3 MAP3K13 MAP3K7 UTRN DNM2	1.20e-04	910	165	14	36736316
Pubmed	ESCRT-I protein UBAP1 controls ventricular expansion and cortical neurogenesis via modulating adherens junctions of radial glial cells.	SATB2 TUBG2 TUBG1	1.31e-04	21	165	3	38402586
Pubmed	PAK4 functions in tumor necrosis factor (TNF) alpha-induced survival pathways by facilitating TRADD binding to the TNF receptor.	TRADD PAK4	1.33e-04	4	165	2	16227624
Pubmed	Hepatitis C virus NS3 protein can activate the Notch-signaling pathway through binding to a transcription factor, SRCAP.	EP400 SRCAP	1.33e-04	4	165	2	21673954
Cytoband	15q15.3	CATSPER2 STRC STRCP1	9.89e-05	25	165	3	15q15.3
Cytoband	Ensembl 112 genes in cytogenetic band chr15q15	RPAP1 CATSPER2 STARD9 STRC STRCP1	2.00e-04	147	165	5	chr15q15
Cytoband	Ensembl 112 genes in cytogenetic band chr6q15	ORC3 RARS2 MAP3K7	8.36e-04	51	165	3	chr6q15
Cytoband	Xp11.2	KDM6A BMP15	2.34e-03	20	165	2	Xp11.2
Cytoband	19p13.11	ATP13A1 ANO8 SLC5A5	2.36e-03	73	165	3	19p13.11
Cytoband	2q37.3	RNPEPL1 ANKMY1 BOK	2.74e-03	77	165	3	2q37.3
Cytoband	17q21.31	LRRC37A2 LRRC37A ASB16	3.28e-03	82	165	3	17q21.31
Cytoband	Ensembl 112 genes in cytogenetic band chr16p12	OTOA COG7 EIF3CL VPS35L	3.55e-03	172	165	4	chr16p12
GeneFamily	Ankyrin repeat domain containing	ANKRD13D ANKK1 ACAP1 ANKMY1 ANKRD27 ANKRD44 ASB18 ASB16 ASB10 MIB1	2.23e-06	242	110	10	403
GeneFamily	Mitogen-activated protein kinase kinase kinases\|RAF family	MAP3K15 MAP3K13 MAP3K7	4.04e-04	24	110	3	654
GeneFamily	WD repeat domain containing\|BEACH domain containing	NBEAL1 WDFY3	1.28e-03	9	110	2	1230
GeneFamily	CD molecules\|Toll like receptors	TLR9 TLR5	1.60e-03	10	110	2	948
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	ACAP1 PLEKHG2 AKT1 VAV3 DNM2 FERMT3	1.63e-03	206	110	6	682
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA11 NBEAL1 SPEG ADAMTS8 RBM20 RYR2 STARD9 UTRN	5.65e-07	191	164	8	04c4d454b57e29a8d1dcdeb4678ce71bdc29b77b
ToppCell	droplet-Thymus-nan-18m-Myeloid-Macrophage\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DCDC2 UPB1 TIFAB ANPEP BOK PRELP TNN	3.16e-06	169	164	7	4ac21e8199de4b6917eacadc56fffc6d886ee643
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NBEAL1 SPEG ARL13A ADAMTS8 RBM20 RYR2 UTRN	3.98e-06	175	164	7	316f2ea930437bf1243b1c0f45e6bd864112c6f2
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NBEAL1 SPEG ARL13A ADAMTS8 RBM20 RYR2 UTRN	3.98e-06	175	164	7	a9f08e1e4c2997dcdd3e5d92daac480da19100b8
ToppCell	T_cells-ISG-high_CD4+_T_cells\|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis	OTOA TRADD APOL1 TRIM22 STAT2 PARP10 DNAH9	4.61e-06	179	164	7	af35ef8a7768cee0c2af0590e5bec35cee6a4714
ToppCell	Pericytes-Donor_03\|World / lung cells shred on cell class, cell subclass, sample id	ITGA11 SPEG RYR2 IGFBP6 PRELP SLIT1 PLCB4	5.33e-06	183	164	7	d04deef7cd4e1738227a6593b84874ce0168c773
ToppCell	droplet-Liver-Hepatocytes-24m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLXND1 PCDH12 TEK ADARB1 TGFBR3 PRELP DCHS1	5.93e-06	186	164	7	2cae34336f184f971f7c8684cc27c23a4e7369ed
ToppCell	droplet-Liver-Hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLXND1 PCDH12 TEK ADARB1 TGFBR3 PRELP DCHS1	5.93e-06	186	164	7	90d53c2597a9f3a2b39afba75adfc54f1ca0a4db
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_VISp_Col6a1_Fezf2\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SATB2 PTPRT SLC5A5 BOK IGFBP6 ADGRF4	6.10e-06	122	164	6	e96aec5af0ed1d8f4cc99fde59dd6998bbc1acbd
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated\|COVID-19_Mild / Disease, condition lineage and cell class	SH2D2A APOL1 SRCAP TRIM22 EIF3CL TGFBR3 UTRN	9.53e-06	200	164	7	2281debd86e5d92e8fe0397aec9ef670800f7471
Disease	Deafness, Sensorineural, And Male Infertility	CATSPER2 STRC	2.89e-05	2	159	2	C1970187
Disease	autosomal recessive nonsyndromic deafness 16 (implicated_via_orthology)	STRC STRCP1	2.89e-05	2	159	2	DOID:0110471 (implicated_via_orthology)
Disease	Deafness-infertility syndrome	CATSPER2 STRC	2.89e-05	2	159	2	cv:C1970187
Disease	chronic granulomatous disease (is_marker_for)	TLR9 TLR5	2.89e-05	2	159	2	DOID:3265 (is_marker_for)
Disease	DEAFNESS-INFERTILITY SYNDROME	CATSPER2 STRC	2.89e-05	2	159	2	611102
Disease	complex cortical dysplasia with other brain malformations 4 (implicated_via_orthology)	TUBG2 TUBG1	2.89e-05	2	159	2	DOID:0090138 (implicated_via_orthology)
Disease	Malformations of Cortical Development	TUBG1 DYNC1H1 TBCD	5.35e-05	14	159	3	C1955869
Disease	Cortical Dysplasia	TUBG1 DYNC1H1 TBCD	5.35e-05	14	159	3	C0431380
Disease	Spermatogenic failure 7	CATSPER2 STRC	8.63e-05	3	159	2	cv:C2751811
Disease	SPERMATOGENIC FAILURE 7	CATSPER2 STRC	8.63e-05	3	159	2	612997
Disease	Spermatogenic Failure 7	CATSPER2 STRC	8.63e-05	3	159	2	C2751811
Disease	Colorectal Carcinoma	ACAP1 SATB2 RNPEPL1 TLR9 PTPRT WAC SLC12A5 RPAP1 DCHS1 LRP1 AKT1 KDM6A EPHA1	1.18e-04	702	159	13	C0009402
Disease	obesity (implicated_via_orthology)	ADAMTS8 PLXND1 F2 ADARB1 EIF6 DCHS1 ZFHX2	1.73e-04	215	159	7	DOID:9970 (implicated_via_orthology)
Disease	eosinophilic esophagitis (is_implicated_in)	CAPN14 ANKRD27	2.85e-04	5	159	2	DOID:13922 (is_implicated_in)
Disease	Microcephaly	PCDH12 TUBG1 DYNC1H1 TBCD	4.78e-04	67	159	4	C0025958
Disease	fish oil supplement exposure measurement, high density lipoprotein cholesterol measurement	SIK3 INTS10	5.95e-04	7	159	2	EFO_0004612, EFO_0600007
Disease	Severe Congenital Microcephaly	TUBG1 DYNC1H1 TBCD	6.18e-04	31	159	3	C3853041
Disease	renal cell carcinoma (is_marker_for)	CA9 FRS2 TLR9 AKT1 KDM6A	6.62e-04	128	159	5	DOID:4450 (is_marker_for)
Disease	Malignant neoplasm of breast	GPI ACAP1 DDX59 LRRC37A2 SIK3 APOL1 TEK EIF6 SLC5A5 LRRC37A MTMR3 AKT1 ADGRF4 MAP3K13 DNAH9	7.29e-04	1074	159	15	C0006142
Disease	Microlissencephaly	TUBG1 DYNC1H1 TBCD	7.44e-04	33	159	3	C1956147
Disease	hepatitis C (is_marker_for)	TLR9 F2 STAT2	8.85e-04	35	159	3	DOID:1883 (is_marker_for)
Disease	renal Wilms' tumor (is_implicated_in)	TEK SALL1	1.26e-03	10	159	2	DOID:5176 (is_implicated_in)
Disease	ankyrin-2 measurement	DDX59 PRELP	1.26e-03	10	159	2	EFO_0021874
Disease	IGF-1 measurement	ITGA11 KIZ ADAMTS8 SRCAP SALL1 STARD9 SLIT1 EIF2B4 DNM2	1.38e-03	488	159	9	EFO_0004627
Disease	Congenital small ears	SALL1 PLCB4 KDM6A	1.41e-03	41	159	3	C0152423
Disease	Congenital Abnormality	SALL1 DLL3	1.54e-03	11	159	2	C0000768
Disease	Cognitive impairment	PTPRT RYR2	1.54e-03	11	159	2	HP_0100543
Disease	collagen disease (implicated_via_orthology)	TLR5 DNM2	1.84e-03	12	159	2	DOID:854 (implicated_via_orthology)
Disease	Prostatic Neoplasms	RNF31 ADAMTS8 WAC SLC5A5 IGFBP6 TLR5 AKT1 VAV3 MAP3K7 KDM6A	1.94e-03	616	159	10	C0033578
Disease	Malignant neoplasm of prostate	RNF31 ADAMTS8 WAC SLC5A5 IGFBP6 TLR5 AKT1 VAV3 MAP3K7 KDM6A	1.94e-03	616	159	10	C0376358
Disease	Anemia, Hemolytic, Acquired	GPI EIF2AK1	2.16e-03	13	159	2	C0002879
Disease	Anemia, Hemolytic	GPI EIF2AK1	2.16e-03	13	159	2	C0002878
Disease	Anemia, Microangiopathic	GPI EIF2AK1	2.16e-03	13	159	2	C0002889
Disease	Microangiopathic hemolytic anemia	GPI EIF2AK1	2.16e-03	13	159	2	C0221021
Disease	Seizures, Focal	SLC12A5 MIB1 DYNC1H1 TBCD	2.46e-03	104	159	4	C0751495
Disease	bone mineral accretion measurement, response to corticosteroid	PTPRT TBCD	2.52e-03	14	159	2	EFO_0007591, GO_0031960
Disease	Nonsyndromic Hearing Loss and Deafness, Autosomal Recessive	OTOA DCDC2 STRC	2.65e-03	51	159	3	cv:CN043650
Disease	attention deficit hyperactivity disorder, bipolar disorder, autism spectrum disorder, schizophrenia, major depressive disorder	KIZ PCLO SLC12A5	2.65e-03	51	159	3	EFO_0003756, EFO_0003888, MONDO_0002009, MONDO_0004985, MONDO_0005090
Disease	Autosomal Recessive Centronuclear Myopathy	SPEG DNM2	2.89e-03	15	159	2	C3645536
Disease	Epilepsy	PCDH12 SLC12A5 RARS2 AKT1	2.91e-03	109	159	4	C0014544
Disease	Blood Platelet Disorders	ABCG8 FERMT3	3.29e-03	16	159	2	C0005818
Disease	Pontoneocerebellar hypoplasia	PCLO RARS2	3.29e-03	16	159	2	cv:C1261175
Disease	allergic rhinitis (is_marker_for)	TLR9 F2	3.72e-03	17	159	2	DOID:4481 (is_marker_for)
Disease	lateral occipital cortex volume measurement	RAB44 UTRN	3.72e-03	17	159	2	EFO_0010311
Disease	perinatal necrotizing enterocolitis (biomarker_via_orthology)	TLR9 TLR5	3.72e-03	17	159	2	DOID:8677 (biomarker_via_orthology)
Disease	phospholipids in VLDL measurement	SIK3 INTS10 ABCG8	4.00e-03	59	159	3	EFO_0022301
Disease	Tachycardia	RYR2 VAV3	4.17e-03	18	159	2	C0039231
Disease	Tachyarrhythmia	RYR2 VAV3	4.17e-03	18	159	2	C0080203
Disease	systemic lupus erythematosus (is_implicated_in)	TLR9 F2 TLR5	4.60e-03	62	159	3	DOID:9074 (is_implicated_in)
Disease	transient cerebral ischemia (implicated_via_orthology)	DAXX PLXND1 ADARB1	5.03e-03	64	159	3	DOID:224 (implicated_via_orthology)
Disease	corneal hysteresis	ADAMTS8 ANAPC1	5.14e-03	20	159	2	EFO_0010066
Disease	Hemorrhage	F2 FERMT3	5.14e-03	20	159	2	C0019080

Protein segments in the cluster

Peptide	Gene	Start	Entry
LTENRVLQNSRHPFL	AKT1	196	P31749
EIPRHLLLTQNNDII	CATR1	6	Q13166
QQRLLLIDSPLHNTF	EP400	1241	Q96L91
EQLLANPHSLRTIAN	EPHA1	881	P21709
HRNLEQESLLPNRVL	C9orf50	391	Q5SZB4
HNLLAAPRAALTRLN	COG7	561	P83436
APRAALTRLNQQAHQ	COG7	566	P83436
GNLESVRVLLRHNAN	ANKRD13D	51	Q6ZTN6
PQRIEQISHAQRLLS	CATSPER2	71	Q96P56
HTLLSQDQAQAARLP	CKAP4	511	Q07065
ERATTNIIQPLLHAQ	ADAMTS8	821	Q9UP79
VARLLVSRQADPNLH	ANKK1	476	Q8NFD2
DAQQRNLRTPLHLAV	ANKK1	521	Q8NFD2
QRNILASNPRVTRFH	ASF1A	136	Q9Y294
ALAQSPEHVVRALLN	ASB10	341	Q8WXI3
LAHLQATDPQQLLRL	ATP13A1	816	Q9HD20
ILREAHLQNVSLPRQ	ADGRF4	301	Q8IZF3
NQPRQLQHLARLAVR	ASB16	406	Q96NS5
QRNPSLHVASLTRQL	CCNI2	276	Q6ZMN8
LRPDQQLHIFNTLRS	CDS2	416	O95674
VRQHNQLLPNLTVRE	ABCG8	151	Q9H221
VVRALRNLADSPQHR	ARMC5	216	Q96C12
RNLADSPQHRLALAQ	ARMC5	221	Q96C12
SPQHRLALAQQGAVR	ARMC5	226	Q96C12
AALTHNAEVPRRRAQ	ACAP1	136	Q15027
SAIRNLERRNHQPIV	ARL13A	166	Q5H913
LQRDHSAIPVINRAQ	ANPEP	646	P15144
SVHALPDALNNLRTQ	DLL3	536	Q9NYJ7
QRDALGRVLVNLNHP	RAD54L2	241	Q9Y4B4
RNVARQLHISLQSEP	BOK	86	Q9UMX3
PSRQEAAHQIVQLIR	DCLRE1B	156	Q9H816
AAARHSLGLPRQQLQ	DAXX	296	Q9UER7
LHQALAACQLLRRQP	EFCC1	566	Q9HA90
IHFNQVRVPATNLIL	ACAD11	601	Q709F0
PELRLRNNGHSVQLT	CA9	191	Q16790
ALHQDILSRVVPLNQ	CAPN14	111	A8MX76
TRQFLQNVREVLQPH	ANO8	476	Q9HCE9
LLNSDHSALPNQRRS	NBEAL1	301	Q6ZS30
QALLSVRPLQAHELN	RBM20	386	Q5T481
HNILEPVVNLARSLR	RAB44	981	Q7Z6P3
LIINNHDVRLPANLL	INTS10	181	Q9NVR2
VNLLFNHPRQRNASR	PCDH12	846	Q9NPG4
SLRQAVQLVLAPHRE	KCNH3	901	Q9ULD8
DLLRQLQVHPEVASQ	RADIL	621	Q96JH8
DVRRLLQSAHPVRVN	ANAPC1	1036	Q9H1A4
LHEPGRQSVTLRQNN	ANKRD27	971	Q96NW4
PSLQAAVENHLEQRL	OTOA	86	Q7RTW8
AAVTHAQRRRLSPLQ	OTOA	1081	Q7RTW8
VRVSILNQNEHSPRL	DCHS1	1091	Q96JQ0
PAAQQLHRENIQRIV	OSGEPL1	81	Q9H4B0
PNNNVRRLIAHVIRT	LRRC37A3	1486	O60309
PNNNVRRLIAHVIRT	LRRC37A2	1486	A6NM11
PNNNVRRLIAHVIRT	LRRC37A	1486	A6NMS7
ELHLSQNAINRISPD	LRIG3	291	Q6UXM1
PQLQEVDLSRNRLAH	LRRC53	181	A6NM62
SIHLSDERNLNAPVQ	LRP1	2211	Q07954
LQASPQRTVQALLNH	ASB18	341	Q6ZVZ8
QRNALTLPHNRTNLT	KDM6A	611	O15550
RPQVRHPLLALSTNN	KIAA1614	866	Q5VZ46
RVLRDGLNSPNHAII	BMP15	326	O95972
IEQLASQLLHNPVRI	DDX59	391	Q5T1V6
QAQAAVLAVLPRLHQ	EBNA1BP2	111	Q99848
IHILQARNLVPRDNN	PCLO	4711	Q9Y6V0
ALEANPTARRTQLQH	PLXND1	1891	Q9Y4D7
VELRQLSRVNHPNIV	MAP3K7	76	O43318
VHPSLQRLQALLQDL	HEXD	451	Q8WVB3
HADVVPNATIRNVLR	PI4KA	1361	P42356
QLHQLPRGRLDLATQ	LRRC45	26	Q96CN5
RAVLHVALRNRSNTP	GPI	96	P06744
QREVAALRLCQSHPN	RPS6KA4	451	O75676
QLLLRHSAPVNAVDN	ANKRD44	856	Q8N8A2
DLRRAPQLNHSNSDV	ITGA11	1051	Q9UKX5
NSEIEAALRPRNHNT	KIZ	651	Q2M2Z5
ELLNTVQRRVQPRLH	MPPED1	266	O15442
QLHLPQVLADAVSRL	ADARB1	316	P78563
LNQQLTNHIRESLPA	DNM2	281	P50570
AQLALVARAHNVPVL	EIF2B4	421	Q9UI10
NLSFNNLTALHPRVL	LRRC70	331	Q7Z2Q7
ADLNARNKRRQTPLH	MIB1	521	Q86YT6
QPAIRVADLLQHITQ	PTPRT	866	O14522
NVAIILASRVDPQLH	OR2B11	46	Q5JQS5
VRRINDNSEAPAHLQ	OTUD3	186	Q5T2D3
HRALQLAQRPVSLLA	GBA	201	P04062
LQHIRNSLPDTVQIR	EIF6	81	P56537
AAALRSPLSNHAQRQ	MAP3K13	676	O43283
SQRHAVDALVLNILP	IL1RL2	396	Q9HB29
ARLPAVVQNAHSLVR	FCSK	951	Q8N0W3
HRTEPTAQQNLALQL	EIF3CL	846	B5ME19
QRNILASNPRVTRFH	ASF1B	136	Q9NVP2
QLLVAQPRRNAQTVH	CHFR	271	Q96EP1
QLPTLRHERSQLQEQ	CROCC	821	Q5TZA2
RRRVAAEHAQPSANL	DOCK8-AS1	161	Q5T8R8
SSIVEQQLPLRRNSH	EIF2AK1	336	Q9BQI3
NAPVAEQVSALHRRI	UPB1	86	Q9UBR1
NFDIRRPSLEHRQLN	FRS2	421	Q8WU20
RDIVRLLLSHGANPN	ANKMY1	676	Q9P2S6
LRRARANLQSVPHAS	APOL1	286	O14791
RINPAHRKLQARLDQ	DYNC1H1	451	Q14204
ESERQQQRPSNILHL	ENAM	1041	Q9NRM1
RAVAELQNPAIRERH	DNAH9	1371	Q9NYC9
QQVALHPARTRLASR	LINC01554	56	Q52M75
NHPAVLRRAEQIQAR	DERA	21	Q9Y315
RHQILLLASQNADLP	SALL1	251	Q9NSC2
RSNQHLICDNLLPGR	RYR2	626	Q92736
ILDHSEQQARPARVN	DCDC2	391	Q9UHG0
GPCRRHLDSVLQQLQ	IGFBP6	161	P24592
LQLARQIHFQASLPA	DELE1	96	Q14154
RHSLECIQANQIFPR	MTMR3	6	Q13615
TPQRLEQHVQALLRA	PARP10	101	Q53GL7
PQRVSHEQFRAALQL	PAK4	296	O96013
NHPQAQRAEESIRRL	SLC12A5	741	Q9H2X9
LNAAPRIALHTALNN	ORC3	591	Q9UBD5
QDAVNKILRNHLIRP	MAP3K15	1096	Q6ZN16
QDRPTLFLEVIQRHN	HPD	341	P32754
QEPQSVSILQHLLRF	RARS2	491	Q5T160
RHPADNRTQIRELGQ	UTRN	1281	P46939
LHPNLRRAIQQILSQ	RNPEPL1	661	Q9HAU8
PADLRTNHTLNNLVE	TRIM35	66	Q9UPQ4
NAQVTELLQRLLHRA	STAT2	301	P52630
QLVSFLNEHQRDPRL	PLCB4	241	Q15147
ALAQHSVPLQLELRA	TRADD	106	Q15628
LPHNLSRQVLQDRGQ	SH2D2A	366	Q9NP31
LDRQNPKRINAVSHL	TEX48	51	A0A1B0GUV7
ENLCTIRRFLNLPQH	SATB2	536	Q9UPW6
ALLTHQLQRLRIQPS	SIK3	716	Q9Y2K2
PQEQHRVISSNLALI	SLC41A3	136	Q96GZ6
QILANRPHTVLLNAT	OPRPN	206	Q99935
NRISSVPAINNRLEH	PRELP	301	P51888
LPQNILSQTSRHNDR	WAC	216	Q9BTA9
NLNLNNFPVHLSRIR	STARD9	1541	Q9P2P6
HRAVLFPQQRLDQLS	SRCAP	1956	Q6ZRS2
RQAQAQHLQEVRLVP	NINL	1241	Q9Y2I6
FQAQQDLLHRTAPLL	NUP160	756	Q12769
PLHQAALAERALQNL	STRC	1296	Q7RTU9
LQLVHALLAENPART	PNMA6A	206	P0CW24
APELNSIIRQQLQAH	TLE5	116	Q08117
SLLLQNTHPRQQALE	RNF31	161	Q96EP0
LVQRNRHAEQQASRP	TFDP1	236	Q14186
RRFQHTSAVILQLQP	PHC2	446	Q8IXK0
GRTFNQIAPLIQHQR	ZNF135	276	P52742
NLEPVLVQLIHSVNR	VPS35L	666	Q7Z3J2
NNHPVRLLTVVRRAN	WDFY3	1116	Q8IZQ1
TPAHRDAQAQRRLQL	ZFHX2	891	Q9C0A1
LRRLGLPHNQLAAQA	SPEG	2501	Q15772
EQNIIFRHNIRLQTP	TNN	81	Q9UQP3
NRIATDRLHIQNPSF	TUBG1	211	P23258
PRQVLTLAQNHSRIN	SLC5A5	216	Q92911
SQNRLHTLLPQTLRN	TLR9	636	Q9NR96
GQDAHLQLQLPRLSR	TIFAB	41	Q6ZNK6
SHAPAVLRQLNEQRL	ZBTB4	11	Q9P1Z0
TTIRNDLALLQLQHP	PRSS42P	161	Q7Z5A4
TPRILEAHQNVAQLS	FERMT3	521	Q86UX7
DAPVALAQRHRQQLQ	PYCARD-AS1	41	I3L0S3
NLTSVLLNNLHPREQ	TEK	596	Q02763
LASQALHRGELQRVP	RPAP1	1071	Q9BWH6
RESPVQHLVAALLAQ	RPAP1	1171	Q9BWH6
RFPENLLLHRVENTQ	ZSWIM3	216	Q96MP5
RLNQFRVDITLPHNE	TRIM49D1	281	C9J1S8
HVFLAPQQARSLLQR	F2	26	P00734
ELRALHSVLQAVPLN	PSMD5	21	Q16401
HSVLQAVPLNELRQQ	PSMD5	26	Q16401
TPLHQAALAERALQN	STRCP1	1296	A6NGW2
ELAARALHNLAQQAP	TBCD	581	Q9BTW9
NRIATDRLHIQNPSF	TUBG2	211	Q9NRH3
LQERQAQLRHSLPLQ	PLEKHG2	216	Q9H7P9
PENALQLSTHNRLRS	WNT8A	66	Q9H1J5
NRLTVLSHNDLPANL	TLR5	536	O60602
TSLRAIQTLHLAQNP	SLIT1	426	O75093
GNLRPNRHLANIVER	TRIM22	66	Q8IYM9
TVHQRDELIRQLQPR	VMAC	86	Q2NL98
PVANRFHLRLENNAE	TGFBR3	346	Q03167
RAHSINLKEINLRPQ	VAV3	51	Q9UKW4
PNAAIQQRLAALRHL	EXD3	256	Q8N9H8