Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	diacylglycerol-dependent serine/threonine kinase activity	PRKD2 PRKD3 PRKCA	1.42e-04	16	130	3	GO:0004697
GeneOntologyMolecularFunction	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	KCNA2 KCNJ6 SCN10A	1.72e-04	17	130	3	GO:0099508
GeneOntologyCellularComponent	axon	PSEN1 ANXA5 MBP MAP7 SYAP1 YWHAE NCDN KCNA2 HMCN2 KCNJ6 SCN10A KCNMA1 LRP2 PRKCA TRAK2 WDFY3 EPHA5	4.24e-05	891	131	17	GO:0030424
GeneOntologyCellularComponent	cell body	PSEN1 YBX1 ANXA5 MBP CCT7 SYAP1 NCDN PTPN13 KCNA2 HMCN2 KCNJ6 KCNMA1 PRKCA TRAK2 WDFY3 NAXE EPHA5	7.10e-05	929	131	17	GO:0044297
GeneOntologyCellularComponent	presynaptic membrane	PSEN1 SYAP1 KCNA2 KCNJ6 CLTA SCN10A KCNMA1 CADPS2	3.65e-04	277	131	8	GO:0042734
Domain	ARHGEF5_35	ARHGEF5 ARHGEF35	4.81e-05	2	130	2	PF15441
Domain	ARHGEF5/35_N	ARHGEF5 ARHGEF35	4.81e-05	2	130	2	IPR029212
Domain	Protein_Kinase_C_mu-related	PRKD2 PRKD3	1.44e-04	3	130	2	IPR015727
Domain	PH	PRKD2 ARHGEF5 PLEKHF1 DGKD PRKD3 APPL1 CADPS2 PLEKHA7 RASAL2	1.44e-04	278	130	9	SM00233
Domain	PH_DOMAIN	PRKD2 ARHGEF5 PLEKHF1 DGKD PRKD3 APPL1 CADPS2 PLEKHA7 RASAL2	1.48e-04	279	130	9	PS50003
Domain	PH_domain	PRKD2 ARHGEF5 PLEKHF1 DGKD PRKD3 APPL1 CADPS2 PLEKHA7 RASAL2	1.52e-04	280	130	9	IPR001849
Domain	PH_dom-like	PRKD2 ARHGEF5 PLEKHF1 DGKD PRKD3 PTPN13 APPL1 WDFY3 CADPS2 PLEKHA7 RASAL2	1.95e-04	426	130	11	IPR011993
Domain	PH	PRKD2 ARHGEF5 PLEKHF1 DGKD PRKD3 APPL1 CADPS2 PLEKHA7	2.04e-04	229	130	8	PF00169
Domain	DAG/PE-bd	PRKD2 PRKD3 PRKCA	4.00e-04	21	130	3	IPR020454
Domain	-	PRKD2 ARHGEF5 PLEKHF1 DGKD PRKD3 PTPN13 APPL1 CADPS2 PLEKHA7 RASAL2	4.13e-04	391	130	10	2.30.29.30
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	PRKD2 CHAF1B CCT7 CBFB YWHAE ANKRD54 FAF1 PTPN13 MIA2 LDB1 MICAL2 KCNJ6 NEMF RETREG1 LRP2 CCDC15 APPL1 WDFY3 CADPS2 BECN1 PRRC2A RASAL2	6.80e-09	1285	137	22	35914814
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	TPM4 MYH9 RIOK1 YBX1 ANXA5 MATR3 CCT7 HSPBP1 MAP7 YWHAE NCDN CTPS2 MIA2 CEBPZ SUPT6H NEMF GOLIM4 GID8 PRRC2A NAXE GOLGB1	1.73e-07	1415	137	21	28515276
Pubmed	VCP phosphorylation-dependent interaction partners prevent apoptosis in Helicobacter pylori-infected gastric epithelial cells.	VIL1 ANXA5 KDM3B CCT7 YWHAE NCDN FAF1 MDN1 APPL1 ARIH1	2.36e-07	288	137	10	23383273
Pubmed	Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.	TPM4 RALGAPA1 MYH9 PSEN1 PDZD11 FYCO1 MAP7 PDIA4 PTPN13 MDN1 CEBPZ WDR89 CDK5RAP2 GID8 GOLGB1	3.22e-07	754	137	15	33060197
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	TPM4 MYH9 RIOK1 YBX1 ANXA5 MATR3 CCT7 MAP7 SYAP1 YWHAE FAF1 PDIA4 SEPHS1 MDN1 CLTA NEMF PRRC2A NAXE	6.64e-07	1149	137	18	35446349
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	PRKD2 MYH9 RIOK1 DNAH10 YBX1 ANXA5 MATR3 CCT7 HSPBP1 SYAP1 YWHAE PDIA4 CLPTM1L MDN1 CEBPZ SUPT6H CLTA NEMF PLEKHA7 RASAL2	8.39e-07	1425	137	20	30948266
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	MATR3 POM121C SYAP1 YWHAE PTPN13 SIPA1L2 PLEKHA7 GOLGB1 RASAL2	1.09e-06	263	137	9	34702444
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	TPM4 PRKD2 MYH9 RIOK1 YBX1 MATR3 CD109 CCT7 MAP7 YWHAE FAF1 PDIA4 LLGL2 CEBPZ CLTA HERC5	1.13e-06	949	137	16	36574265
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	MYH9 MATR3 FYCO1 YWHAE NCDN KCNA2 MDN1 LDB1 KCNMA1 PRKCA CDK5RAP2 APPL1 WDFY3 PRRC2A GOLGB1 RASAL2	1.37e-06	963	137	16	28671696
Pubmed	β-Actin mRNA interactome mapping by proximity biotinylation.	TPM4 MYH9 YBX1 MATR3	2.30e-06	24	137	4	31189591
Pubmed	Defining the membrane proteome of NK cells.	MYH9 CARMIL2 ANXA5 MATR3 MARCHF6 FYCO1 CBFB YWHAE NCDN CLPTM1L MDN1 MIA2 CLTA BUB1 GOLIM4 PRRC2A GOLGB1	3.73e-06	1168	137	17	19946888
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	TPM4 CHAF1B YBX1 ANXA5 CD109 NAPG CCT7 MAP7 YWHAE CLPTM1L MDN1 LDB1 CEBPZ CLTA RWDD1 PRKCA GID8 PRRC2A HERC5	3.98e-06	1440	137	19	30833792
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	RALGAPA1 PDZD11 HSPBP1 MAP7 NCDN PDIA4 CLPTM1L PTPN13 MDN1 CEBPZ SUPT6H CLTA RWDD1 RETREG1 CDK5RAP2 SIPA1L2 GOLGB1 RASAL2 HERC5	6.29e-06	1487	137	19	33957083
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	RALGAPA1 CARMIL2 ARHGEF5 MATR3 KDM3B MAP7 YWHAE PTPN13 MDN1 SIPA1L2 BECN1 PLEKHA7 GOLGB1 RASAL2	8.32e-06	861	137	14	36931259
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	PRKD2 MYH9 KDM3B CCT7 YWHAE FAF1 PRKD3 FBXO38 CTPS2 SUPT6H CLTA ARIH1 PLEKHA7 ZRANB1 PRRC2A	1.08e-05	1005	137	15	19615732
Pubmed	Large-scale proteomics and phosphoproteomics of urinary exosomes.	VIL1 GPR155 MYH9 ANXA5 NAPG YWHAE PTPN13 SCN10A LRP2 PRKCA CDK5RAP2 APPL1 CFAP70 PLEKHA7 PRRC2A	1.22e-05	1016	137	15	19056867
Pubmed	Mapping of three members of the mouse protein disulfide isomerase family.	PDIA4 LRP2 PRKCA	1.28e-05	12	137	3	9457688
Pubmed	Angiotensin II directly triggers endothelial exocytosis via protein kinase C-dependent protein kinase D2 activation.	PRKD2 PRKCA	1.54e-05	2	137	2	17951978
Pubmed	The CTRB1-CTRB2 risk allele for chronic pancreatitis discovered in European populations does not contribute to disease risk variation in the Chinese population due to near allele fixation.	CTRB2 CTRB1	1.54e-05	2	137	2	28951524
Pubmed	Protein kinase Ds promote tumor angiogenesis through mast cell recruitment and expression of angiogenic factors in prostate cancer microenvironment.	PRKD2 PRKD3	1.54e-05	2	137	2	30841931
Pubmed	Genome-wide association study identifies inversion in the CTRB1-CTRB2 locus to modify risk for alcoholic and non-alcoholic chronic pancreatitis.	CTRB2 CTRB1	1.54e-05	2	137	2	28754779
Pubmed	Antiviral activity of ISG15 against classical swine fever virus replication in porcine alveolar macrophages via inhibition of autophagy by ISGylating BECN1.	BECN1 HERC5	1.54e-05	2	137	2	32093773
Pubmed	Molecular cloning and nucleotide sequence of human pancreatic prechymotrypsinogen cDNA.	CTRB2 CTRB1	1.54e-05	2	137	2	2917002
Pubmed	The PLEKHA7-PDZD11 complex regulates the localization of the calcium pump PMCA and calcium handling in cultured cells.	PDZD11 PLEKHA7	1.54e-05	2	137	2	35714771
Pubmed	Genomic cloning and partial characterization of human chymotrypsinogen gene.	CTRB2 CTRB1	1.54e-05	2	137	2	8186414
Pubmed	Protein kinase D3 conditional knockout impairs osteoclast formation and increases trabecular bone volume in male mice.	PRKD2 PRKD3	1.54e-05	2	137	2	37044359
Pubmed	Dual role of protein kinase C on BK channel regulation.	KCNMA1 PRKCA	1.54e-05	2	137	2	20385812
Pubmed	FBXO38 mediates FGL1 ubiquitination and degradation to enhance cancer immunity and suppress inflammation.	FBXO38 FGL1	1.54e-05	2	137	2	37938970
Pubmed	Protein kinase d isoforms differentially modulate cofilin-driven directed cell migration.	PRKD2 PRKD3	1.54e-05	2	137	2	24840177
Pubmed	Chymotrypsin Reduces the Severity of Secretagogue-Induced Pancreatitis in Mice.	CTRB2 CTRB1	1.54e-05	2	137	2	30076839
Pubmed	Sequencing of the complex CTRB1-CTRB2 locus in chronic pancreatitis.	CTRB2 CTRB1	1.54e-05	2	137	2	33036922
Pubmed	Evolutionary relationships between laboratory mice and subspecies of Mus musculus based on the restriction fragment length variants of the chymotrypsin gene at the Prt-2 locus.	CTRB2 CTRB1	1.54e-05	2	137	2	2565717
Pubmed	Phosphorylation of adaptor protein containing pleckstrin homology domain, phosphotyrosine binding domain, and leucine zipper motif 1 (APPL1) at Ser430 mediates endoplasmic reticulum (ER) stress-induced insulin resistance in hepatocytes.	PRKCA APPL1	1.54e-05	2	137	2	22685300
Pubmed	Opposing growth regulatory roles of protein kinase D isoforms in human keratinocytes.	PRKD2 PRKD3	1.54e-05	2	137	2	25802335
Pubmed	Protein kinases D2 and D3 are novel growth regulators in HCC1806 triple-negative breast cancer cells.	PRKD2 PRKD3	1.54e-05	2	137	2	23393329
Pubmed	Autoantibodies to harmonin and villin are diagnostic markers in children with IPEX syndrome.	VIL1 USH1C	1.54e-05	2	137	2	24250806
Pubmed	The plasma membrane translocation of diacylglycerol kinase delta1 is negatively regulated by conventional protein kinase C-dependent phosphorylation at Ser-22 and Ser-26 within the pleckstrin homology domain.	DGKD PRKCA	1.54e-05	2	137	2	15228384
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	SECISBP2L RIOK1 PDZD11 ANXA5 HSPBP1 MAP7 USH1C POM121C YWHAE PTPN13 CLTA BUB1 TTC21B APPL1 GID8 PLEKHA7 RASAL2	1.84e-05	1321	137	17	27173435
Pubmed	LukS-PV inhibits hepatocellular carcinoma cells migration by downregulating HDAC6 expression.	TPM4 MYH9 YBX1 ANXA5 MATR3 CD109 MAP7 YWHAE PDIA4 CLTA GOLGB1	2.01e-05	580	137	11	35676659
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	TPM4 MYH9 RIOK1 MATR3 GPATCH1 KDM3B CCT7 POM121C SYAP1 PTPN13 SIPA1L2 PRRC2A GOLGB1 HERC5	2.05e-05	934	137	14	33916271
Pubmed	FBXO32 links ubiquitination to epigenetic reprograming of melanoma cells.	HSPBP1 NCDN SUPT6H APPL1 ARIH1 GMPPA HERC5	2.23e-05	212	137	7	33462405
Pubmed	Mechanistic insights into COVID-19 by global analysis of the SARS-CoV-2 3CLpro substrate degradome.	FYCO1 FAF1 SUPT6H PRRC2A	2.52e-05	43	137	4	34672947
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	RALGAPA1 MYH9 RIOK1 CCT7 SYAP1 YWHAE PDIA4 CLPTM1L PTPN13 PRRC2A GOLGB1 RASAL2	2.53e-05	708	137	12	39231216
Pubmed	Autophagic degradation of the inhibitory p53 isoform Δ133p53α as a regulatory mechanism for p53-mediated senescence.	TPM4 MYH9 YBX1 CCT7 CLTA	2.66e-05	88	137	5	25144556
Pubmed	Proteome analysis of the circadian clock protein PERIOD2.	MATR3 CCT7 YWHAE PRKD3 PRKCA	3.65e-05	94	137	5	35122331
Pubmed	Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction.	CDKN2C FAF1 SCN10A	3.90e-05	17	137	3	21076409
Pubmed	Ubiquitination of UVRAG by SMURF1 promotes autophagosome maturation and inhibits hepatocellular carcinoma growth.	YWHAE BECN1 ZRANB1	3.90e-05	17	137	3	30686098
Pubmed	ALS/FTD-causing mutation in cyclin F causes the dysregulation of SFPQ.	TPM4 CHAF1B MYH9 YBX1 MATR3 CCT7 YWHAE PDIA4 MDN1 GMPPA NAXE	3.91e-05	624	137	11	33729478
Pubmed	A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.	CHAF1B YBX1 MATR3 PTPN13 ARIH1 SIPA1L2 PRRC2A	3.96e-05	232	137	7	25515538
Pubmed	Functional and therapeutic significance of protein kinase D enzymes in invasive breast cancer.	PRKD2 PRKD3	4.61e-05	3	137	2	26253275
Pubmed	PLEKHA7 Recruits PDZD11 to Adherens Junctions to Stabilize Nectins.	PDZD11 PLEKHA7	4.61e-05	3	137	2	27044745
Pubmed	Cooperative binding of the tandem WW domains of PLEKHA7 to PDZD11 promotes conformation-dependent interaction with tetraspanin 33.	PDZD11 PLEKHA7	4.61e-05	3	137	2	32371390
Pubmed	A Novel Conserved Domain Mediates Dimerization of Protein Kinase D (PKD) Isoforms: DIMERIZATION IS ESSENTIAL FOR PKD-DEPENDENT REGULATION OF SECRETION AND INNATE IMMUNITY.	PRKD2 PRKD3	4.61e-05	3	137	2	27662904
Pubmed	APPL1 promotes glucose uptake in response to mechanical stretch via the PKCζ-non-muscle myosin IIa pathway in C2C12 myotubes.	MYH9 APPL1	4.61e-05	3	137	2	27478065
Pubmed	Genetic study of pancreatic proteinase in mice (Mus musculus): linkage of the Prt-2 locus on chromosome 8.	CTRB2 CTRB1	4.61e-05	3	137	2	1016231
Pubmed	Bidirectional control of BK channel open probability by CAMKII and PKC in medial vestibular nucleus neurons.	KCNMA1 PRKCA	4.61e-05	3	137	2	21307321
Pubmed	Protein kinase C mediates platelet secretion and thrombus formation through protein kinase D2.	PRKD2 PRKCA	4.61e-05	3	137	2	21527521
Pubmed	Evolutionary expansion of polyaspartate motif in the activation peptide of mouse cationic trypsinogen limits autoactivation and protects against pancreatitis.	CTRB2 CTRB1	4.61e-05	3	137	2	34643096
Pubmed	Loss of chymotrypsin-like protease (CTRL) alters intrapancreatic protease activation but not pancreatitis severity in mice.	CTRB2 CTRB1	4.61e-05	3	137	2	32678161
Pubmed	Effect of deletion of the protein kinase PRKD1 on development of the mouse embryonic heart.	PRKD2 PRKD3	4.61e-05	3	137	2	38419169
Pubmed	Expression of the protein kinase D (PKD) family during mouse embryogenesis.	PRKD2 PRKD3	4.61e-05	3	137	2	16377259
Pubmed	Identification of a protein that interacts with the golli-myelin basic protein and with nuclear LIM interactor in the nervous system.	MBP LDB1	4.61e-05	3	137	2	14743429
Pubmed	Inhibition of protein kinase D by CID755673 promotes maintenance of the pluripotency of embryonic stem cells.	PRKD2 PRKD3	4.61e-05	3	137	2	32747433
Pubmed	Lack of PRKD2 and PRKD3 kinase domain somatic mutations in PRKD1 wild-type classic polymorphous low-grade adenocarcinomas of the salivary gland.	PRKD2 PRKD3	4.61e-05	3	137	2	26426580
Pubmed	PKD2 interacts with Lck and regulates NFAT activity in T cells.	PRKD2 NFATC2	4.61e-05	3	137	2	19192391
Pubmed	Secretagogue-induced pancreatitis in mice devoid of chymotrypsin.	CTRB2 CTRB1	4.61e-05	3	137	2	38981616
Pubmed	Studies on the phosphorylation of myelin basic protein by protein kinase C and adenosine 3':5'-monophosphate-dependent protein kinase.	MBP PRKCA	4.61e-05	3	137	2	2413024
Pubmed	Genetic study of pancreatic proteinase in mice (Mus musculus): genetic variants of trypsin and chymotrypsin.	CTRB2 CTRB1	4.61e-05	3	137	2	1008801
Pubmed	The P-body component USP52/PAN2 is a novel regulator of HIF1A mRNA stability.	TPM4 MYH9 RIOK1 YBX1 MATR3 CCT7 YWHAE CLTA	5.01e-05	328	137	8	23398456
Pubmed	LIM-domain transcription complexes interact with ring-finger ubiquitin ligases and thereby impact islet β-cell function.	YBX1 MATR3 LDB1	5.53e-05	19	137	3	31186351
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	CHAF1B YBX1 ANXA5 MATR3 CCT7 YWHAE NCDN PDIA4 MDN1 CEBPZ SUPT6H CLTA PRKCA GOLGB1	5.56e-05	1024	137	14	24711643
Pubmed	Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.	TPM4 MYH9 RIOK1 MATR3 FYCO1 MAP7 FAF1 PDIA4 SUPT6H NEMF RWDD1	5.88e-05	653	137	11	33742100
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	TPM4 MYH9 YBX1 GON7 KDM3B CCT7 HSPBP1 MAP7 YWHAE NCDN FAF1 PDIA4 CTPS2 APPL1 GID8 ARIH1 GMPPA	6.16e-05	1455	137	17	22863883
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	SECISBP2L PRKD2 RIOK1 YBX1 KDM3B FYCO1 SYAP1 NCDN ANKRD54 CTPS2 RWDD1 WDR89 TRAK2 BECN1	6.43e-05	1038	137	14	26673895
Pubmed	TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions.	SFSWAP YBX1 MATR3 CCT7 FYCO1 HSPBP1 YWHAE PTPN13 LDB1 GOLIM4 CDK5RAP2 GID8 PRRC2A	7.63e-05	922	137	13	27609421
Pubmed	MARK3-mediated phosphorylation of ARHGEF2 couples microtubules to the actin cytoskeleton to establish cell polarity.	PDZD11 MAP7 YWHAE PTPN13	7.74e-05	57	137	4	29089450
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	RALGAPA1 MBP YWHAE NCDN FAF1 PTPN13 LDB1 PLXDC2 MICAL2 SUPT6H NEMF TTC21B SAMD13 KCNMA1 ARIH1 ZRANB1 GOLGB1	8.16e-05	1489	137	17	28611215
Pubmed	SETDB2 Links E2A-PBX1 to Cell-Cycle Dysregulation in Acute Leukemia through CDKN2C Repression.	CDKN2C SETDB2	9.19e-05	4	137	2	29694893
Pubmed	Genomic analysis of fibrolamellar hepatocellular carcinoma.	CLPTM1L PRKCA	9.19e-05	4	137	2	25122662
Pubmed	PPARγ regulates resistance vessel tone through a mechanism involving RGS5-mediated control of protein kinase C and BKCa channel activity.	KCNMA1 PRKCA	9.19e-05	4	137	2	22962432
Pubmed	Single nucleotide polymorphisms in C-type lectin genes, clustered in the IBD2 and IBD6 susceptibility loci, may play a role in the pathogenesis of inflammatory bowel diseases.	CLEC4A CLEC2D	9.19e-05	4	137	2	22664939
Pubmed	Activation and substrate specificity of the human protein kinase C alpha and zeta isoenzymes.	MBP PRKCA	9.19e-05	4	137	2	8375396
Pubmed	Protein kinase D regulates basolateral membrane protein exit from trans-Golgi network.	PRKD2 PRKD3	9.19e-05	4	137	2	14743217
Pubmed	CBFbeta is critical for AML1-ETO and TEL-AML1 activity.	RUNX1T1 CBFB	9.19e-05	4	137	2	19179469
Pubmed	Protein kinase D regulates positive selection of CD4+ thymocytes through phosphorylation of SHP-1.	PRKD2 PRKD3	9.19e-05	4	137	2	27670070
Pubmed	Proteomic dissection of cell type-specific H2AX-interacting protein complex associated with hepatocellular carcinoma.	ANXA5 MATR3 YWHAE PDIA4 NAXE	9.56e-05	115	137	5	20000738
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	MATR3 HSPBP1 MAP7 HMCN2 PLXDC2 CADPS2 PRRC2A FHIP2B	9.75e-05	361	137	8	26167880
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	SECISBP2L TPM4 VIL1 MYH9 RIOK1 SFSWAP YBX1 PDZD11 ANXA5 MATR3 YWHAE PRKD3 CEBPZ CLTA NEMF PRRC2A	1.04e-04	1371	137	16	36244648
Pubmed	Systematic protein-protein interaction mapping for clinically relevant human GPCRs.	MATR3 MARCHF6 MBP CBFB POM121C YWHAE CLPTM1L CEBPZ KCNJ6 RETREG1 GOLGB1	1.05e-04	697	137	11	28298427
Pubmed	PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation.	MYH9 YBX1 MATR3 CCT7 YWHAE NCDN PDIA4 CEBPZ TERB1	1.21e-04	477	137	9	31300519
Pubmed	Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.	TPM4 MYH9 YBX1 MATR3 CCT7 YWHAE PDIA4 SEPHS1 MDN1 SUPT6H CLTA GOLGB1	1.39e-04	847	137	12	35235311
Pubmed	Chromosomal assignments of genes for trypsin, chymotrypsin B, and elastase in mouse.	CTRB2 CTRB1	1.53e-04	5	137	2	6589791
Pubmed	The consensus coding sequences of human breast and colorectal cancers.	CD109 MIA2	1.53e-04	5	137	2	16959974
Pubmed	Genetic study of pancreatic proteinase and alpha-amylase in mice (Mus musculus).	CTRB2 CTRB1	1.53e-04	5	137	2	4461036
Pubmed	Protein kinase D regulates RhoA activity via rhotekin phosphorylation.	PRKD2 PRKD3	1.53e-04	5	137	2	22228765
Pubmed	Genetic and biochemical characterization of a new chymotrypsin isozyme of the house mouse, CTRA-1.	CTRB2 CTRB1	1.53e-04	5	137	2	1820020
Pubmed	Heterodimeric interaction and interfaces of S100A1 and S100P.	MYH9 S100A2	1.53e-04	5	137	2	15171681
Pubmed	The functional interactome landscape of the human histone deacetylase family.	TPM4 CCT7 YWHAE MDN1 CEBPZ APPL1 ZSCAN2	1.56e-04	289	137	7	23752268
Pubmed	Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.	CAPN12 RIOK1 DNAH10 KDM3B YWHAE SEPHS1 LLGL2 KCNA2 LRP2 PRKCA ARIH1	1.57e-04	730	137	11	34857952
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	TPM4 RALGAPA1 MYH9 CARMIL2 MATR3 MBP CCT7 MAP7 YWHAE NCDN MICAL2 PRKCA SIPA1L2 PLEKHA7 PRRC2A RASAL2	1.70e-04	1431	137	16	37142655
Interaction	YWHAZ interactions	RALGAPA1 PRKD2 CHAF1B MYH9 CARMIL2 PDZD11 ARHGEF5 MATR3 MBP MAP7 YWHAE FAF1 PTPN13 LDB1 NFATC2 KCNMA1 PRKCA CDK5RAP2 APPL1 WDFY3 SIPA1L2 PLEKHA7 ZRANB1 PRRC2A RASAL2	1.76e-06	1319	134	25	int:YWHAZ
Interaction	MUS81 interactions	RIOK1 MBP CCT7 S100A2 PRKCA CDK5RAP2 ZRANB1	8.32e-06	109	134	7	int:MUS81
Interaction	GSK3B interactions	MYH9 PSEN1 YBX1 CCT7 MAP7 RUNX1T1 SYAP1 PDIA4 PTPN13 NFATC2 CEBPZ PRKCA GID8 TRAK2 ARIH1 SIPA1L2 ZRANB1 RASAL2	1.81e-05	868	134	18	int:GSK3B
Interaction	ALAD interactions	TPM4 GON7 HSPBP1 ARHGEF35 KCNMA1	2.44e-05	52	134	5	int:ALAD
Interaction	SERF2 interactions	RIOK1 PDZD11 MAP7 PDIA4 ZRANB1 PRRC2A	2.51e-05	87	134	6	int:SERF2
Interaction	VCL interactions	TPM4 MYH9 HSPBP1 YWHAE PDIA4 CLTA TTC21B PRKCA SIPA1L2 ZRANB1	3.80e-05	305	134	10	int:VCL
Interaction	IQGAP1 interactions	TPM4 MYH9 RIOK1 YBX1 ANXA5 MATR3 YWHAE FAF1 S100A2 NFATC2 CLTA GOLIM4 ARIH1 ZRANB1	4.03e-05	591	134	14	int:IQGAP1
Interaction	YWHAB interactions	RALGAPA1 CHAF1B RIOK1 CARMIL2 ARHGEF5 MATR3 MAP7 YWHAE PDIA4 PTPN13 CTPS2 NFATC2 KCNMA1 APPL1 SIPA1L2 BECN1 PLEKHA7 ZRANB1 RASAL2	4.20e-05	1014	134	19	int:YWHAB
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	PRKD2 PLEKHF1 DGKD PRKD3 APPL1 CADPS2 PLEKHA7 RASAL2	4.70e-06	206	83	8	682
GeneFamily	Zinc fingers FYVE-type\|Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors	PLEKHF1 FYCO1 WDFY3	3.82e-04	31	83	3	81
Coexpression	GSE1432_CTRL_VS_IFNG_6H_MICROGLIA_UP	PRKD2 CHAF1B OLFML2B FYCO1 SEPHS1 MICAL2 KCNMA1 WDFY3 FHIP2B	1.06e-06	200	136	9	M3404
Coexpression	GSE40493_BCL6_KO_VS_WT_TREG_UP	GIMAP1 CCT7 FBXO38 CTPS2 SUPT6H RWDD1 GOLIM4 APPL1	4.16e-06	177	136	8	M9401
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC28A3 MAP7 PTPN13 MICAL2 PRKCA CADPS2 PLEKHA7	1.84e-06	188	136	7	4bdf8d49af0e9da349b16e3f012e1b0eec04cc4f
ToppCell	Globus_pallidus-Endothelial\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	TPM4 MYH9 ARHGEF5 LLGL2 CLEC2D GOLIM4 FILIP1L	1.91e-06	189	136	7	ad7dc9d25edd68fb624380a082c389fe7d640e7d
ToppCell	IPF-Epithelial-Basal\|Epithelial / Disease state, Lineage and Cell class	TPM4 MYH9 CD109 FAF1 S100A2 FAT2 PLXDC2	1.98e-06	190	136	7	4f15842b424eefadbfe451875e517cf70e29607f
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar-AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SECISBP2L DGKD MAP7 PTPN13 MICAL2 LRP2 CADPS2	2.60e-06	198	136	7	2e2a4e1756bba6f4fbe529559a97d2993c890b4b
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DGKD MAP7 PTPN13 LLGL2 MICAL2 CADPS2 PLEKHA7	2.69e-06	199	136	7	8587bd98de7767a575088afbea07a1feb4516b9b
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	CARMIL2 GIMAP1 NFATC2 BUB1 TTC21B CLEC2D	9.88e-06	160	136	6	8e2b51d7b42e0b6e62641efdbbc73d31561d6a3e
ToppCell	Healthy_donor-CD8+_T_naive\|World / disease group, cell group and cell class (v2)	GPR155 GIMAP1 NT5C1B RETREG1 CLEC2D PRKCA	1.02e-05	161	136	6	8a61395af33132783a0a37956c6f821aba5d3b1e
ToppCell	Mild/Remission-B_naive-4\|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)	SECISBP2L MATR3 DGKD ZBTB10 APPL1 BANK1	1.35e-05	169	136	6	c3a6179a64589a370108fea809b157839347759c
ToppCell	COPD-Epithelial-Basal\|Epithelial / Disease state, Lineage and Cell class	TPM4 S100A2 FAT2 LDB1 PLXDC2 KCNMA1	1.81e-05	178	136	6	441d1dba720141891b11f404744c59834d80e6c5
ToppCell	wk_08-11-Epithelial-PNS-Proliferating_Schwann\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	CDKN2C OLFML2B MBP KCNA2 RETREG1 EPHA5	1.87e-05	179	136	6	ab23fee9adab1e63d5b5cd9faba6b9a92beef425
ToppCell	LPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	OLFML2B SLC28A3 MAP7 PTPN13 CADPS2 PLEKHA7	1.87e-05	179	136	6	fd2cbee532e7b44113410dca82aec7db1a7fb69f
ToppCell	TCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-1\|TCGA-Thryoid / Sample_Type by Project: Shred V9	TPM4 OLFML2B SLC28A3 THBS2 CLEC4A KCNJ6	2.12e-05	183	136	6	06e4b05d86a7d643569e19575c2c9aa351d33f29
ToppCell	COVID-19-Epithelial_cells-AT2\|COVID-19 / group, cell type (main and fine annotations)	MAP7 PTPN13 MICAL2 LRP2 CADPS2 PLEKHA7	2.18e-05	184	136	6	369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MAP7 PTPN13 MICAL2 PRKCA CADPS2 PLEKHA7	2.32e-05	186	136	6	e83718fabb057100835d3357df407f283d23fe16
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-lymphocytic-T_lymphocytic-effector_CD4-positive,_alpha-beta_T_cell\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	GPR155 MATR3 GIMAP1 CLEC2D ZBTB10 PRKCA	2.39e-05	187	136	6	e61c1755531469dd3850c9740474b5ad4e0499c1
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CAPN12 USH1C MIA2 PLXDC2 LRP2 WDFY3	2.39e-05	187	136	6	9d77ca45f7563bd6f2a0c1be5d99d93ad30983f7
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D231\|Adult / Lineage, Cell type, age group and donor	DGKD MAP7 PTPN13 MICAL2 LRP2 CADPS2	2.54e-05	189	136	6	dab54a52358f66a8a9460cd6089a06c5fa7e7a5d
ToppCell	LA-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	TPM4 MYH9 HMCN2 MICAL2 KCNMA1 RASAL2	2.54e-05	189	136	6	6b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TPM4 THBS2 HMCN2 MICAL2 KCNMA1 FILIP1L	2.61e-05	190	136	6	2e88e366d377d74deb53a4ea870973ce5c6532e8
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TPM4 THBS2 HMCN2 MICAL2 KCNMA1 FILIP1L	2.61e-05	190	136	6	0028f886c789ba238c031eae5d96acaed4af8c25
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SECISBP2L YBX1 MATR3 GOLIM4 GOLGB1 FILIP1L	2.69e-05	191	136	6	60c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SECISBP2L YBX1 MATR3 GOLIM4 GOLGB1 FILIP1L	2.69e-05	191	136	6	973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCell	Adult-Epithelial\|Adult / Lineage, Cell type, age group and donor	MAP7 PTPN13 LLGL2 MICAL2 CADPS2 PLEKHA7	2.77e-05	192	136	6	efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SECISBP2L MAP7 PTPN13 MICAL2 LRP2 CADPS2	2.85e-05	193	136	6	fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCell	nucseq\|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MATR3 FAF1 PLXDC2 ARIH1 PLEKHA7 RASAL2	2.85e-05	193	136	6	779276e775cb2492e8dd36436295a536084a6415
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SECISBP2L MAP7 PTPN13 MICAL2 LRP2 CADPS2	2.85e-05	193	136	6	f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SECISBP2L DGKD MAP7 PTPN13 MICAL2 CADPS2	2.94e-05	194	136	6	97534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCell	P15-Mesenchymal-myocytic_cell-aortic_smooth_muscle_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	OLFML2B PLEKHF1 CD109 THBS2 KCNMA1 FILIP1L	2.94e-05	194	136	6	5f04d21c4e2d36e74b6c5889aa97fd98f75a0973
ToppCell	Fibroblasts-DKK3+_Fibroblasts\|Fibroblasts / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	CD109 THBS2 HMCN2 MICAL2 NRK KCNMA1	3.11e-05	196	136	6	24d64b67aa9b0e8215ad06f9101c1314b3483620
ToppCell	CV-Moderate-6\|CV / Virus stimulation, Condition and Cluster	TPM4 NFATC2 APPL1 ARIH1 NAXE GOLGB1	3.11e-05	196	136	6	7bced0cc2112697593c478fa291b8ed3941fb811
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating_2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	CDKN2C CHAF1B BUB1 RETREG1 CCDC15 HERC5	3.11e-05	196	136	6	34bd155e6d848eb53d613997c0e244535de30ba3
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SLC28A3 MAP7 PDIA4 PTPN13 CADPS2 GOLGB1	3.20e-05	197	136	6	1485933986921ff45669d9b7501c8d17050b3e97
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SECISBP2L PTPN13 LLGL2 CADPS2 PLEKHA7 GOLGB1	3.20e-05	197	136	6	3d13a4f2e86422900ee2194e8a1fd1cf9750d5d3
ToppCell	LPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_only / Treatment groups by lineage, cell group, cell type	OLFML2B SLC28A3 MAP7 PTPN13 CADPS2 GOLGB1	3.20e-05	197	136	6	1a1bee8da6e04b65935c40373eaee4d6c046d9a1
ToppCell	PND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CDKN2C OLFML2B ANXA5 THBS2 GOLIM4 FILIP1L	3.29e-05	198	136	6	b2d295e330772bd8e24da356c75564b4297ea9c5
ToppCell	PND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CDKN2C OLFML2B ANXA5 THBS2 GOLIM4 FILIP1L	3.29e-05	198	136	6	ce59ee3d970397eb62d6387699c6c6cd65457898
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	OLFML2B SLC28A3 MAP7 PDIA4 PTPN13 CADPS2	3.29e-05	198	136	6	285f729140b1df029c24f6ca1d2438470ac51794
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar-AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SECISBP2L MAP7 PTPN13 MICAL2 LRP2 CADPS2	3.29e-05	198	136	6	f948391296c261c473d339069a6d0f20ccd6f38f
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	FAF1 PTPN13 PRKCA WDFY3 CADPS2 PLEKHA7	3.29e-05	198	136	6	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	PND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CDKN2C OLFML2B ANXA5 THBS2 GOLIM4 FILIP1L	3.29e-05	198	136	6	3ffaea4b44067d69f954b2bd3119c88a55ab232a
ToppCell	Bronchial-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SECISBP2L MAP7 LLGL2 MICAL2 CADPS2 PLEKHA7	3.39e-05	199	136	6	5f7da3eab58ace6cddb3179a415cd839d5767958
ToppCell	Parenchymal-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MAP7 PTPN13 LLGL2 MICAL2 CADPS2 PLEKHA7	3.39e-05	199	136	6	5cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCell	Transverse-Macrophage-LYVE1_Macrophage\|Transverse / Region, Cell class and subclass	OLFML2B PLXDC2 SAMD13 KCNMA1 SIPA1L2 FILIP1L	3.39e-05	199	136	6	facf79c256db5ae57bdb613e86ec90616a6f67ca
ToppCell	Transverse-(6)_Macrophage-(61)_LYVE1_Macrophage\|Transverse / shred on region, Cell_type, and subtype	OLFML2B PLXDC2 SAMD13 KCNMA1 SIPA1L2 FILIP1L	3.39e-05	199	136	6	dcc2a7f4d1fa30aaaad655dd59c5a2b039d264bf
ToppCell	3'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TPM4 OLFML2B MBP THBS2 HMCN2 NRK	3.39e-05	199	136	6	eeb7d370d4dfacf705306c72ccc4919ddefacff1
ToppCell	LPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	MAP7 USH1C S100A2 PDIA4 PTPN13 CADPS2	3.39e-05	199	136	6	121de4e02585de3a3010398387c523bacf8ce546
ToppCell	tumor_Lung-Fibroblasts-Myofibroblasts\|Fibroblasts / Location, Cell class and cell subclass	TPM4 MYH9 S100A2 THBS2 MICAL2 FILIP1L	3.39e-05	199	136	6	f89d67e3d8cd48ef5c30a5ad71764f4ebbc8bcb3
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56\|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)	MYH9 ANXA5 GIMAP1 S100A12 PLXDC2 CLTA	3.48e-05	200	136	6	8f585920bf7ad8bb489c78e2db42435962de4416
ToppCell	metastatic_Lymph_Node-Fibroblasts-Myofibroblasts\|Fibroblasts / Location, Cell class and cell subclass	TPM4 MYH9 THBS2 MICAL2	7.40e-05	73	136	4	116259a036373bccaeb77fe3c675741a5ca81c52
ToppCell	Mild/Remission-B_naive-4\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	SECISBP2L MATR3 DGKD ZBTB10 BANK1	9.16e-05	148	136	5	dd5e1bc02824e743e1c030a303e32f27a359a8ca
ToppCell	droplet-Kidney-KIDNEY-30m-Lymphocytic-Epcam____proximal_tube_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CAPN12 FGL1 CTRB1 SIPA1L2 BANK1	1.25e-04	158	136	5	1d78578dc1f8ba43dacdccae1082c0b9d749f64d
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig-Z\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MYH9 GIMAP1 LLGL2 NFATC2 CLEC2D	1.28e-04	159	136	5	bf8ff9251bcb64b2b9d6dd93461aec97659686ec
ToppCell	facs-Limb_Muscle-Muscle_Diaphragm-18m-Lymphocytic-B_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GIMAP1 DGKD DDX25 PRKCA BANK1	1.28e-04	159	136	5	656aa20706bdba81bbcc3e68e6058215b92b8802
ToppCell	droplet-Lung-immune-endo-depleted-3m-Lymphocytic-B_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRKD2 GIMAP1 THBS2 DDX25 BANK1	1.28e-04	159	136	5	74655c22e9fdd88e3052b9dfb954c8fb678bd2d8
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CAPN12 CDKN2C PRKD2 CHAF1B CD109	1.44e-04	163	136	5	7864e966c228282b4b63c43164dba3faba21026d
ToppCell	343B-Myeloid-Macrophage-SPP1+_Macrophage\|343B / Donor, Lineage, Cell class and subclass (all cells)	RIOK1 ANXA5 PLXDC2 CLEC4A KCNMA1	1.48e-04	164	136	5	057ca87847373eff7fe97dd9f4358509e66ca4c3
ToppCell	ICU-SEP-Lymphocyte-T_NK-dnT\|ICU-SEP / Disease, Lineage and Cell Type	CAPN12 CTPS2 TRMT44 CCDC15 ARIH1	1.57e-04	166	136	5	96d92316cee20b722fe782db9dafcceb8f2c220b
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	MATR3 CLEC2D PRKCA TRAK2 GOLGB1	1.61e-04	167	136	5	ced6ed9b412739c6ced622523347c10295edbf53
ToppCell	facs-Limb_Muscle-forelimb_and_hindlimb-18m-Lymphocytic-T_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CARMIL2 FYCO1 KCNA2 WDR89 ZSCAN2	1.66e-04	168	136	5	182f08106ac65ea501e2fb9139d3b44b7c4662c9
ToppCell	TCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-8\|TCGA-Thryoid / Sample_Type by Project: Shred V9	CD109 NCDN CDK5RAP2 TRAK2 SIPA1L2	1.66e-04	168	136	5	00646601548b0fee42ae16bfa5e93603bc7c5129
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CAPN12 CD109 ANKLE1 BUB1 CDK5RAP2	1.85e-04	172	136	5	2b6cd84c946b1e800caba452ae70145ea285fec1
ToppCell	COVID-19-Heart-Neuronal\|Heart / Disease (COVID-19 only), tissue and cell type	GPR155 PTPN13 RETREG1 PRKCA SIPA1L2	1.90e-04	173	136	5	6fb5f9e6536a5d57fd8e6657b494047a2d0bc9c7
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	OLFML2B CD109 ANKLE1 MICAL2 BUB1	1.95e-04	174	136	5	1779e67382cb2644534ffb5b9b8f28d32935f4ea
ToppCell	343B-Myeloid-Macrophage-FABP4+_Macrophage\|343B / Donor, Lineage, Cell class and subclass (all cells)	CARMIL2 MATR3 PLXDC2 CLEC4A KCNMA1	2.01e-04	175	136	5	d3890bd0c570bb81434fdd1c5229891cefe2e462
ToppCell	facs-Marrow-B-cells-24m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP2 WDR89 CTRB1 BANK1 EPHA5	2.01e-04	175	136	5	887e75fc90e59a6394d62f3c048a9cfdf6707725
ToppCell	LPS-IL1RA+antiTNF-Lymphocytic_NKT-T_cells-T-cells\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CARMIL2 MBP NFATC2 RETREG1 CLEC2D	2.06e-04	176	136	5	9d4a4dfeebb5a8a0f3ab18c37c8ddc2cd2158575
ToppCell	LPS-IL1RA+antiTNF-Lymphocytic_NKT-T_cells\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CARMIL2 MBP NFATC2 RETREG1 CLEC2D	2.06e-04	176	136	5	bb41e9478373726eb460af764de0277b2d09928e
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CDKN2C OLFML2B ANKLE1 THBS2 BUB1	2.11e-04	177	136	5	4197cf2b1e743230c821f422836fa5991b155a52
ToppCell	LPS_only-Lymphocytic_B-B_cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GPR155 DGKD SETDB2 RETREG1 BANK1	2.11e-04	177	136	5	c82332c5f656aa26513e4f7525d5d4d733019725
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CDO1 OLFML2B THBS2 PLXDC2 NRK	2.11e-04	177	136	5	7af1a19692f7fe8f691178a4e57d62bc379e3d56
ToppCell	LPS_only-Lymphocytic_B\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GPR155 DGKD SETDB2 RETREG1 BANK1	2.11e-04	177	136	5	5ed65e08d773d157840317c72e0d43c261d438d4
ToppCell	LPS_only-Lymphocytic_B-B_cells-B-cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GPR155 DGKD SETDB2 RETREG1 BANK1	2.11e-04	177	136	5	8a955a7ab84c434f9ad4b467246b8be3cb479406
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CAPN12 VIL1 USH1C RETREG1 LRP2	2.23e-04	179	136	5	58ae5a97fe2a14e1c6fdeb886397eb06fdaf0428
ToppCell	COVID-19-kidney-PCT-S2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CAPN12 MAP7 USH1C RETREG1 LRP2	2.29e-04	180	136	5	358923e4228035a3e90e2957392089219e90dcd7
ToppCell	Control-Epithelial_cells-AT2\|Control / group, cell type (main and fine annotations)	SECISBP2L PTPN13 MICAL2 LRP2 CADPS2	2.29e-04	180	136	5	198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCell	3'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SECISBP2L MBP KCNA2 PRKCA EPHA5	2.29e-04	180	136	5	38490017dd590e3fcfa7e88d8d15235d55f90cf1
ToppCell	TCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-2\|TCGA-Skin / Sample_Type by Project: Shred V9	FYCO1 PRKD3 TRAK2 RASAL2 EPHA5	2.34e-04	181	136	5	9d5b331cabc5524f0a9fd8b571e87be4c447c7d4
ToppCell	wk_08-11-Mesenchymal-Chondrocyte-ASPN+_chondrocyte\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	OLFML2B UCMA THBS2 NRK EPHA5	2.40e-04	182	136	5	0e52ba34e179d9bfaac7b49920b44c710b2b8dad
ToppCell	P28-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CDKN2C CDO1 ANXA5 PLXDC2 PRKCA	2.40e-04	182	136	5	19c5e3a9d9b3728303b682102e276adfe93aa759
ToppCell	tumor_Lung-Myeloid_cells-Undetermined\|tumor_Lung / Location, Cell class and cell subclass	YBX1 ANXA5 CLEC4A CLTA KCNMA1	2.47e-04	183	136	5	7ef79365514e62dfc2e182e873e2b413d4f46b46
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Lymphocytic-B_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GIMAP1 DGKD DDX25 RETREG1 BANK1	2.47e-04	183	136	5	544939a0bfef082d361d88ef70d6f0923b8d9af9
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Mesenchymal-ependymal_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC28A3 USH1C UCMA LRP2 CFAP70	2.47e-04	183	136	5	6ca7c2d7c56e0f1b9038ba677b4c1c3dfd63bfce
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Mesenchymal-Ependyma\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC28A3 USH1C UCMA LRP2 CFAP70	2.47e-04	183	136	5	18040d0653286071df959513c63d94b555a5d00a
ToppCell	COVID-19-Heart-EC_3\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CD109 RUNX1T1 CC2D2B CADPS2 RASAL2	2.47e-04	183	136	5	ff95382cfed592190d0636d2b750328471f82e0d
ToppCell	B_cell_maturation-plasma\|World / Lineage and Cell class	TPM4 PDIA4 CLPTM1L KCNMA1 CADPS2	2.47e-04	183	136	5	0c3cb61912df05f1beba1004540770ef1a4de786
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC28A3 MAP7 PTPN13 MICAL2 CADPS2	2.53e-04	184	136	5	ab2f06906fc7a9931dfa0864ef506832b07fb93e
ToppCell	Control-Epithelial_alveolar-AT_2-Differentiating_AT2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SECISBP2L MAP7 PTPN13 CADPS2 PLEKHA7	2.59e-04	185	136	5	0d2add28ac1f4fa6de7699be009bf8391badaf4c
ToppCell	10x3'2.3-week_14-16-Myeloid_macrophage-stroma-osteoclast\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	PLEKHF1 CD109 S100A2 CLEC4A FILIP1L	2.59e-04	185	136	5	5ed49b6d8214c6119355a6d3ee4e25d40bcc0c53
ToppCell	normal-na-Myeloid-conventional_dendritic_cell-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	TPM4 ANXA5 YWHAE PLXDC2 CLEC4A	2.59e-04	185	136	5	67e881a89a491665b8c612fff084c202c0c79235
ToppCell	Fetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MYH9 DGKD THBS2 MICAL2 FILIP1L	2.59e-04	185	136	5	e58a009aaf342be019a909747b1895d5987d4daf
ToppCell	10x5'-lymph-node_spleen-Hematopoietic_progenitors-Progenitor_pre-Lymphocytic-T\|lymph-node_spleen / Manually curated celltypes from each tissue	PSEN1 OLFML2B MAP7 ZSCAN30 BUB1	2.66e-04	186	136	5	17eec1efad1f5e9ced1eb6bc9eb5dd7ded789c61
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MAP7 PTPN13 LLGL2 CADPS2 PLEKHA7	2.66e-04	186	136	5	4e94158db52df41d71e67b02b9895a358eebee0f
ToppCell	droplet-Liver-LIVER-30m-Lymphocytic\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDKN2C OLFML2B GIMAP1 PTPN13 PRKCA	2.66e-04	186	136	5	ad55da1dbb173721101126826b6db9d3434cb377
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MATR3 MAP7 PTPN13 MICAL2 CADPS2	2.66e-04	186	136	5	acfa68a2afb7d2b51c9b469a1965fe5cc5d5e64e
ToppCell	COVID-19-kidney-tDL\|kidney / Disease (COVID-19 only), tissue and cell type	CAPN12 MAP7 USH1C MIA2 LRP2	2.72e-04	187	136	5	d35d27ca3c0e65f92f4508e1cb98a743f44fdcdf
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SECISBP2L PTPN13 LLGL2 CADPS2 PLEKHA7	2.72e-04	187	136	5	58d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PTPN13 DDX25 LRP2 CDK5RAP2 FHIP2B	2.72e-04	187	136	5	f5a202d5f8eb57b57d80815ce98774e04c387383
ToppCell	(1)_T_CD4_naive\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	GPR155 GIMAP1 RETREG1 CLEC2D PRKCA	2.79e-04	188	136	5	b8f67ac2faadd5b848955e43ab5d6cf5e49b3681
ToppCell	LA-13._Vascular_Smooth_Muscle\|LA / Chamber and Cluster_Paper	TPM4 HMCN2 MICAL2 KCNMA1 RASAL2	2.79e-04	188	136	5	34e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCell	droplet-Marrow-nan-21m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDKN2C YBX1 OLFML2B GIMAP1 BANK1	2.79e-04	188	136	5	2c4432cada1273d08cbdc2824922cf578e448ec8
Drug	AC1L1JQC	PRKD2 MBP PRKD3 PRKCA	2.65e-06	17	135	4	CID000005157
Drug	(S)-1,2-Diolein	PRKD2 MBP DGKD PRKD3 PRKCA	1.16e-05	50	135	5	CID000001324
Drug	bisindolylmaleimide II	PRKD2 ANXA5 PRKD3 PRKCA	2.17e-05	28	135	4	CID000002397
Drug	bisindolylmaleimide V	PRKD2 ANXA5 PRKD3 PRKCA	2.17e-05	28	135	4	CID000002400
Drug	AC1L3G0K	PRKD2 ANXA5 PRKD3 PRKCA	2.87e-05	30	135	4	CID000114822
Drug	BOCPheONP	CTRB2 CTRB1	3.49e-05	2	135	2	CID000111308
Drug	MPM-06	CTRB2 CTRB1	3.49e-05	2	135	2	CID000161546
Drug	NSC-374899	CTRB2 CTRB1	3.49e-05	2	135	2	CID000435726
Drug	methylbenzenebutanoate	CTRB2 CTRB1	3.49e-05	2	135	2	CID000281254
Drug	Asp-Arg-Val-Tyr-Val-His-Pro-Phe-His-Leu	CTRB2 CTRB1	3.49e-05	2	135	2	CID004418081
Drug	c189	CTRB2 CTRB1	3.49e-05	2	135	2	CID000248048
Drug	dansyl-D-arginine methyl ester	CTRB2 CTRB1	3.49e-05	2	135	2	CID000191369
Drug	methyl 6-phenylhexanoate	CTRB2 CTRB1	3.49e-05	2	135	2	CID011820300
Drug	5-aminotetrazole	CTRB2 CTRB1	3.49e-05	2	135	2	CID000020467
Drug	2-bromoisobutyric acid	CTRB2 CTRB1	3.49e-05	2	135	2	CID000074924
Drug	p-toluamidine	CTRB2 CTRB1	3.49e-05	2	135	2	CID000122753
Drug	N-acetyl-alpha-azaphenylalanine phenyl ester	CTRB2 CTRB1	3.49e-05	2	135	2	CID000191275
Drug	isobutyl sulfide	CTRB2 CTRB1	3.49e-05	2	135	2	CID000011607
Drug	K00077	TPM4 PRKD2 MBP PRKD3 KCNJ6 SCN10A PRKCA CDK5RAP2	5.18e-05	220	135	8	CID006419759
Drug	Lga-afc	MBP CTRB2 CTRB1	5.58e-05	13	135	3	CID003081120
Drug	AC1L1ERT	PRKD2 ANXA5 PRKD3 NRK PRKCA	5.64e-05	69	135	5	CID000002920
Drug	norathyriol	PRKD2 MBP PRKD3 PRKCA	6.71e-05	37	135	4	CID005281656
Drug	C-1b	PRKD2 DGKD PRKD3 KCNMA1 PRKCA	6.92e-05	72	135	5	CID006102740
Drug	RK-1409B	PRKD2 PRKD3 PRKCA	8.80e-05	15	135	3	CID003036125
Drug	1-stearoyl-2-arachidonylglycerol	PRKD2 PRKD3 PRKCA	8.80e-05	15	135	3	CID006443869
Drug	dansyl-DAG	PRKD2 PRKD3 PRKCA	8.80e-05	15	135	3	CID000129493
Drug	dichloromethanediamine	PRKD2 YBX1 ANXA5 MAP7 RUNX1T1 PRKD3 SUPT6H KCNJ6 SCN10A KCNMA1 LRP2 PRKCA	9.06e-05	539	135	12	CID005311048
Drug	1-stearoyl-2-arachidonoyl-sn-glycerol	PRKD2 DGKD PRKD3 PRKCA	9.15e-05	40	135	4	CID000001398
Drug	N-acetylbenzotriazole	CTRB2 CTRB1	1.04e-04	3	135	2	CID000087784
Drug	photophor	CTRB2 CTRB1	1.04e-04	3	135	2	CID000014780
Drug	dibutyl iodomethaneboronate	CTRB2 CTRB1	1.04e-04	3	135	2	CID000098591
Drug	zinc;dipicolinate	CTRB2 CTRB1	1.04e-04	3	135	2	CID004309911
Drug	2-oxobut-3-ynoate	CTRB2 CTRB1	1.04e-04	3	135	2	CID000171547
Drug	AFMeq	CTRB2 CTRB1	1.04e-04	3	135	2	CID000194069
Drug	Bz-Cti-otbu	CTRB2 CTRB1	1.04e-04	3	135	2	CID006452691
Drug	n-(2-oxoethyl)benzamide	CTRB2 CTRB1	1.04e-04	3	135	2	CID000188995
Drug	AC1L49DM	CTRB2 CTRB1	1.04e-04	3	135	2	CID000152933
Drug	c140	CTRB2 CTRB1	1.04e-04	3	135	2	CID002783250
Drug	Benzamidomethaneboronic acid	CTRB2 CTRB1	1.04e-04	3	135	2	CID000127677
Drug	phenyl hippurate	CTRB2 CTRB1	1.04e-04	3	135	2	CID000076323
Drug	FK-386	CTRB2 CTRB1	1.04e-04	3	135	2	CID000135044
Drug	FK-375	CTRB2 CTRB1	1.04e-04	3	135	2	CID000135042
Drug	carbostyril-124	CTRB2 CTRB1	1.04e-04	3	135	2	CID000088277
Drug	N-trifluoroacetyl-4-fluorophenylalanine	CTRB2 CTRB1	1.04e-04	3	135	2	CID000328214
Drug	C18 4	CTRB2 CTRB1	1.04e-04	3	135	2	CID000077248
Drug	taraxastane	CTRB2 CTRB1	1.04e-04	3	135	2	CID006429404
Drug	Phe-phe-ome	CTRB2 CTRB1	1.04e-04	3	135	2	CID000151728
Drug	phenylethaneboronic acid	CTRB2 CTRB1	1.04e-04	3	135	2	CID000065389
Drug	3-amino-2-pyridone	CTRB2 CTRB1	1.04e-04	3	135	2	CID000322353
Drug	ASA-BMPA	CTRB2 CTRB1	1.04e-04	3	135	2	CID003035649
Drug	p-nitrophenyl benzoate	CTRB2 CTRB1	1.04e-04	3	135	2	CID000070396
Drug	Z-Phe-OMe	CTRB2 CTRB1	1.04e-04	3	135	2	CID003082435
Drug	3-methylcoumarin	CTRB2 CTRB1	1.04e-04	3	135	2	CID000017130
Drug	2-propyl methylphosphonochloridate	CTRB2 CTRB1	1.04e-04	3	135	2	CID000102124
Drug	FK-316	CTRB2 CTRB1	1.04e-04	3	135	2	CID000133688
Drug	AC1L19T8	CTRB2 CTRB1	1.04e-04	3	135	2	CID000000694
Drug	Marinostatin D	CTRB2 CTRB1	1.04e-04	3	135	2	CID000132206
Drug	1FD7	CTRB2 CTRB1	1.04e-04	3	135	2	CID000445579
Drug	Glt-leu-phe-nh-meq	CTRB2 CTRB1	1.04e-04	3	135	2	CID000194914
Drug	AC1L4Z4F	CTRB2 CTRB1	1.04e-04	3	135	2	CID000194913
Drug	Glt-Phe-NH-FMeq	CTRB2 CTRB1	1.04e-04	3	135	2	CID000194912
Drug	diacetyl trimer	CTRB2 CTRB1	1.04e-04	3	135	2	CID000193527
Drug	FK-448	CTRB2 CTRB1	1.04e-04	3	135	2	CID006917869
Drug	Ac-Phe-OMe	CTRB2 CTRB1	1.04e-04	3	135	2	CID000097805
Drug	thiobenzyl N-heptafluorobutyrylanthranilate	CTRB2 CTRB1	1.04e-04	3	135	2	CID000133906
Drug	AC1LDMDX	PRKD2 PRKD3 PRKCA BECN1	1.22e-04	43	135	4	CID000621355
Drug	kazinol B	CTRB2 PRKCA CTRB1	1.30e-04	17	135	3	CID000480869
Drug	daphnoretin	PRKD2 PRKD3 PRKCA	1.30e-04	17	135	3	CID005281406
Drug	Cytosar-U	PRKD2 ANXA5 SLC28A3 RUNX1T1 CBFB NT5C1B PDIA4 PRKD3 CTPS2 PRKCA	1.38e-04	399	135	10	CID000000596
Drug	dihydrosterculic acid	PRKD2 PRKD3 PRKCA	1.56e-04	18	135	3	CID000160788
Drug	dipalmitin	PRKD2 PRKD3 PRKCA	1.56e-04	18	135	3	CID000068149
Drug	Cgp-42700	PRKD2 PRKD3 PRKCA	1.56e-04	18	135	3	CID000188390
Drug	agelasine B	PRKD2 MBP PRKD3 PRKCA	1.59e-04	46	135	4	CID006439899
Drug	pinacidil	PRKD2 PRKD3 KCNA2 KCNJ6 PRKCA	1.70e-04	87	135	5	CID000004826
Drug	TAPP-Br	PRKD2 PRKD3 PRKCA	1.84e-04	19	135	3	CID000160326
Drug	sapintoxin A	PRKD2 PRKD3 PRKCA	1.84e-04	19	135	3	CID000108085
Drug	AC1NRBT8	SEPHS1 CLTA APPL1	1.84e-04	19	135	3	CID005288622
Drug	Pz-plgpa	PSEN1 CTRB2 CTRB1	1.84e-04	19	135	3	CID000152296
Drug	ICI182,780; Down 200; 1uM; PC3; HT_HG-U133A	MAP7 LDB1 BUB1 WDFY3 CADPS2 BECN1 RASAL2	1.95e-04	200	135	7	5931_DN
Drug	1,3-diolein	PRKD2 MBP DGKD PRKD3 PRKCA	2.00e-04	90	135	5	CID000033120
Drug	1,2-dicaprin	PRKD2 DGKD PRKD3 PRKCA	2.04e-04	49	135	4	CID000001321
Drug	Benzoyl-dl-leucine	CTRB2 CTRB1	2.08e-04	4	135	2	CID000294887
Drug	Acafcek	CTRB2 CTRB1	2.08e-04	4	135	2	CID000197677
Drug	B-1,3-od	CTRB2 CTRB1	2.08e-04	4	135	2	CID011971053
Drug	dehydromerodesmosine	CTRB2 CTRB1	2.08e-04	4	135	2	CID006443540
Drug	alpha-amyrin palmitate	CTRB2 CTRB1	2.08e-04	4	135	2	CID000185477
Drug	poly-THIQ	CTRB2 CTRB1	2.08e-04	4	135	2	CID006453487
Drug	N-(4-carboxycyclohexylmethyl)-maleimide	CTRB2 CTRB1	2.08e-04	4	135	2	CID011548799
Drug	G2505_sigma	CTRB2 CTRB1	2.08e-04	4	135	2	CID000111098
Drug	p-fluorobenzenesulfonyl chloride	CTRB2 CTRB1	2.08e-04	4	135	2	CID000009588
Drug	BSSDA	CTRB2 CTRB1	2.08e-04	4	135	2	CID003081106
Drug	AC1L2HV6	CTRB2 CTRB1	2.08e-04	4	135	2	CID000047328
Drug	AC1L4X1Z	CTRB2 CTRB1	2.08e-04	4	135	2	CID000193815
Drug	NSC-676827	CTRB2 CTRB1	2.08e-04	4	135	2	CID000385555
Drug	6-amino-1,2-benzopyrone	CTRB2 CTRB1	2.08e-04	4	135	2	CID000046152
Drug	nitrophenylethanol	CTRB2 CTRB1	2.08e-04	4	135	2	CID000097851
Drug	soman	PRKD2 CTRB2 PRKD3 PRKCA CTRB1	2.21e-04	92	135	5	CID000007305
Drug	triphosphoinositide	PRKD2 DGKD PRKD3 KCNA2 KCNJ6 NRK SCN10A PRKCA	2.30e-04	273	135	8	CID009543520
Drug	mepivacaine	PRKD2 PRKD3 SCN10A PRKCA	2.38e-04	51	135	4	CID000004062
Drug	diradylglycerol	PRKD2 DGKD PRKD3 PRKCA	2.38e-04	51	135	4	CID006437874
Disease	level of chymotrypsinogen B2 in blood serum	CTRB2 CTRB1	1.90e-05	2	129	2	OBA_2041192
Disease	chymotrypsinogen B measurement	CTRB2 CTRB1	5.67e-05	3	129	2	EFO_0801477
Disease	Malignant neoplasm of breast	TPM4 CDKN2C MYH9 YBX1 CD109 GIMAP1 CBFB CLPTM1L LLGL2 MIA2 GOLIM4 APPL1 PRRC2A GOLGB1 RASAL2	7.36e-05	1074	129	15	C0006142
Disease	Ischemic stroke, large artery stroke	CDKN2C FAF1	2.81e-04	6	129	2	EFO_0005524, HP_0002140
Disease	cytochrome c oxidase subunit 6C measurement	PLXDC2 PRKCA	2.81e-04	6	129	2	EFO_0801515
Disease	Hereditary Sensory Autonomic Neuropathy, Type 5	RETREG1 SCN10A	3.93e-04	7	129	2	C0020075
Disease	Diaphragmatic Hernia	KCNA2 KCNMA1 LRP2	7.71e-04	41	129	3	C0019284
Disease	JT interval	CDKN2C RIOK1 OLFML2B DGKD PRKCA CFAP70	7.98e-04	248	129	6	EFO_0007885
Disease	heart rate response to exercise	PLEKHF1 RP1L1 SCN10A	8.87e-04	43	129	3	EFO_0009184
Disease	trypsin-2 measurement	CTRB2 CTRB1	1.02e-03	11	129	2	EFO_0008305
Disease	Weight Gain	TPM4 ANXA5 PRKD3 KCNMA1	1.06e-03	102	129	4	C0043094
Disease	autoimmune thyroiditis (is_implicated_in)	LRP2 BANK1	1.22e-03	12	129	2	DOID:7188 (is_implicated_in)
Disease	level of C-X-C motif chemokine 2 in blood serum	OLFML2B NAXE	1.22e-03	12	129	2	OBA_2041207
Disease	Mouth Diseases	CHAF1B S100A12	1.22e-03	12	129	2	C0026636
Disease	Metabolic Bone Disorder	KCNMA1 LRP2	1.67e-03	14	129	2	C0005944
Disease	T wave morphology measurement	OLFML2B SCN10A	1.67e-03	14	129	2	EFO_0008398
Disease	gout	PRKD2 SLC28A3 RUNX1T1 LRP2 PRKCA	1.74e-03	196	129	5	EFO_0004274
Disease	schizophrenia (biomarker_via_orthology)	MBP BECN1	1.92e-03	15	129	2	DOID:5419 (biomarker_via_orthology)
Disease	level of C-X-C motif chemokine 3 in blood serum	OLFML2B NAXE	1.92e-03	15	129	2	OBA_2041208
Disease	Osteopenia	KCNMA1 LRP2	1.92e-03	15	129	2	C0029453
Disease	shigellosis	CHAF1B RIOK1	2.19e-03	16	129	2	EFO_0005585
Disease	cyclic adenosine monophosphate measurement	ANXA5 NT5C1B	2.47e-03	17	129	2	EFO_0010473
Disease	diabetic neuropathy (biomarker_via_orthology)	MBP BECN1	2.47e-03	17	129	2	DOID:9743 (biomarker_via_orthology)
Disease	ischemia (biomarker_via_orthology)	PRKCA BECN1	2.77e-03	18	129	2	DOID:326 (biomarker_via_orthology)
Disease	Brugada syndrome	SCN10A PRKCA	3.09e-03	19	129	2	MONDO_0015263
Disease	citrulline measurement	HMCN2 RP1L1	3.42e-03	20	129	2	EFO_0009777
Disease	BMI-adjusted waist-hip ratio, physical activity measurement	DNAH10 CTRB2 CTRB1	3.47e-03	69	129	3	EFO_0007788, EFO_0008002
Disease	lung cancer	MAP7 ZRANB1	3.77e-03	21	129	2	MONDO_0008903
Disease	type 1 diabetes mellitus	PRKD2 CTRB2 NEMF CLEC2D CTRB1	4.30e-03	242	129	5	MONDO_0005147

Protein segments in the cluster

Peptide	Gene	Start	Entry
DQIVEVNGVDFSNLD	USH1C	256	Q9Y6N9
EGQLQDADQQLEFLN	TTC21B	371	Q7Z4L5
EQQQQQREDEDDYEA	NT5C1B	266	Q96P26
FSIQEIDINNEQEND	BANK1	401	Q8NDB2
QGDGEEQNKEALQDV	YWHAE	236	P62258
AGEFDQGSDEENIQV	CTRB2	86	Q6GPI1
DVQADEDALAQQFEQ	ANKLE1	421	Q8NAG6
NDVETVQQLLEDGAD	ANKRD54	121	Q6NXT1
DNFILGNGFLEQDDE	BUB1	921	O43683
QGEAAVRQAEDAIQN	CARMIL2	751	Q6F5E8
EVQVLEEQGQQEAGF	ARHGEF5	226	Q12774
FESDDQNGRNIKENQ	EPHA5	156	P54756
EVQVLEEQGQQEAGF	ARHGEF35	226	A5YM69
PEQIAFQDEDEAQLN	CHAF1B	101	Q13112
GIDEAQVEQDAQALF	ANXA5	166	P08758
QVEQDAQALFQAGEL	ANXA5	171	P08758
GVNLQNVAESEEEEF	CC2D2B	126	Q6DHV5
RNIDGSINNINEDDE	DDX25	41	Q9UHL0
EGFQEQLNQCAELLE	CDK5RAP2	1296	Q96SN8
EEDFQQLQAQEGVAI	RAD9A	201	Q99638
EEFDQGLDVVLDDNQ	ARHGAP36	271	Q6ZRI8
AEDENNIDNRTNFDG	GON7	76	Q9BXV9
FENNQADLENATEVL	ARIH1	491	Q9Y4X5
EEEGNEAANFDLAVV	CT47A1	96	Q5JQC4
QEQNLDQTYLDDVNE	NFATC2	896	Q13469
IQEGVNNSNEDFREE	KCNA2	461	P16389
DQIGNEEQVEDTFQK	MDN1	4691	Q9NU22
SQEEAQAVDQELFNE	NAXE	61	Q8NCW5
EELDQENEAALENGI	MATR3	721	P43243
ENEAALENGIKNEEN	MATR3	726	P43243
VGAQALQAEEQEAAF	MAGEA11	136	P43364
NENGVSVQNENFEEI	MAP7	681	Q14244
VNDTNVQFLDQDDDD	KCNMA1	1006	Q12791
AVEQVEADLLQDQEG	LLGL2	541	Q6P1M3
LENTQFDAANGIDDE	LDB1	361	Q86U70
EAEEANDLSQQVANL	NCDN	431	Q9UBB6
EEQDLDQQGNEENLF	NEMF	966	O60524
QAAEDALAVINQQED	RUNX1T1	496	Q06455
AQEEEQYLQSGDQQL	GPR155	641	Q7Z3F1
EQTERNGDVANLENE	KCNJ6	406	P48051
QLEEQGRQLQAAEEA	FYCO1	1031	Q9BQS8
TNVAGEDDQDFNVLI	HMCN2	2721	Q8NDA2
ENLNEQLEEFLANIG	APPL1	216	Q9UKG1
QAEAERLDQEEAQYQ	BECN1	216	Q14457
NQTVNKDVDAQAEGE	GPATCH1	731	Q9BRR8
QVLAYDADEGQNADV	FAT2	2606	Q9NYQ8
DILVYEEQQQAAAGE	FHIP2B	61	Q86V87
GDQVLAVNDVDFQDI	PDZD11	91	Q5EBL8
EFDEERAQQEDALAQ	CBFB	126	Q13951
NGQYEEDVEETEQNL	RASAL2	966	Q9UJF2
QEFGDQDVDLVNCRN	KDM3B	1436	Q7LBC6
FNEDEDINDQIQNAA	PRKD2	751	Q9BZL6
FNEDEDINDQIQNAA	PRKD3	776	O94806
LGDQEENENSANQQV	MARCHF6	571	O60337
EAQLQELQVKFNEGE	MYH9	1251	P35579
GIQNGLDVEFDDAEQ	LRP2	1776	P98164
DNEICEQFIAQLENG	OVOS2	261	Q6IE36
TVEEEDQIFLDGQEN	POM121C	301	A8CG34
NQGEDEFEEAEQVRE	GOLIM4	556	O00461
NLQTLLDDEGDNFEE	HERC5	816	Q9UII4
EENDFRQDLQPGEQQ	FBXO38	521	Q6PIJ6
DVFQRNQQDGQLEDS	GMPPA	196	Q96IJ6
FQELAGEEEELNASQ	CAPN12	556	Q6ZSI9
QNQEAFDLDVAVKEN	CD109	1276	Q6YHK3
EFQADVNIEDNEGNL	CDKN2C	91	P42773
ENVYGLEENAQSRQE	GIMAP1	11	Q8WWP7
AVINGQLYEESENQD	FILIP1L	821	Q4L180
QLFAGDEVNVEEVQA	CDO1	21	Q16878
EQLQLFAFEAEVNEN	CFAP70	636	Q5T0N1
QENEVQFLDKGDENT	FGL1	56	Q08830
ALEFAQTQLAEQGEE	GID8	121	Q9NWU2
QNSAFLDIGDENEIQ	CADPS2	341	Q86UW7
EDNEVFGEADANQNN	MBP	41	P02686
VDEQNAQTQEQEGFV	DGKD	631	Q16760
NAENEGDALLQFTAE	FAF1	326	Q9UNN5
DEEVLQGEQGDFNDN	BMP2KL	16	Q5H9B9
PDFNDAVEQVLEENG	DNAH10	2071	Q8IVF4
AGEFDQGSDEENIQV	CTRB1	86	P17538
IDDLQQGELEAFIQN	CEBPZ	76	Q03701
DDAVENNQLAFDVAE	MICAL2	571	O94851
DEEAQNLLNENNAAG	PTPN13	2066	Q12923
GELDFEENNAYEIQV	PCDHA12	306	Q9UN75
IAVEDENDLEELNNG	MIA2	256	Q96PC5
LDQNNVIENEETGEF	MIA2	486	Q96PC5
QDLDQVPEEFQGQDQ	NRK	511	Q7Z2Y5
GNDDLDNQVDQANDV	NRK	951	Q7Z2Y5
AEQAADQQEREGALE	HSPBP1	111	Q9NZL4
LAAQQRQEEAEEQGA	PLEKHF1	211	Q96S99
DDILFEDLQDNVNEN	RIOK1	36	Q9BRS2
EDLQDNVNENGEGEI	RIOK1	41	Q9BRS2
NEAENLEENEEPFVA	SFSWAP	176	Q12872
EEAQGQCQQEEAQRE	TRMT44	101	Q8IYL2
QGNSRQVVEQDEEED	PSEN1	56	P49768
EIFQGLDANQDEQVD	S100A12	56	P80511
LDANQDEQVDFQEFI	S100A12	61	P80511
DQLVIANIDQSDFEG	PRKCA	641	P17252
NILLENQNDDEEEEG	NBPF7P	276	P0C2Y1
ERQQQEEEAQEAGAA	RETREG1	36	Q9H6L5
DIVNFERQEQEGEQY	PLEKHA7	331	Q6IQ23
NLKEFDQLDQENDDG	PRRC2A	311	P48634
LLDDGQDNNTQIEED	PLXDC2	96	Q6UX71
QENHFQEDEQFLGAV	SEPHS1	46	P49903
QSEGQQDEQLDLDFV	SIPA1L2	121	Q9P2F8
GVDINNEDIADNFEA	CCT7	476	Q99832
EEQASAFQEQEIDGK	SAMD13	66	Q5VXD3
DEDGFQELNENGNAK	SECISBP2L	391	Q93073
ENGVLVLNDANFDNF	PDIA4	61	P13667
ESAEEELQQAGDQEL	SYAP1	36	Q96A49
NVGFQNEENFLENEN	SLC28A3	16	Q9HAS3
EIGIAVQDAEDQGFQ	MROH2B	761	Q7Z745
EDETLQNEADNQENV	OLFML2B	41	Q68BL8
NDIEEQQDEFFSGDN	OLFML2B	311	Q68BL8
IEDEENQNELFQQQA	CCDC15	156	Q0P6D6
GAENNIDLVLNVEDF	CLPTM1L	66	Q96KA5
QDADLAQVESFQELN	CLEC2D	106	Q9UHP7
TQEEQDFIFQNLQEE	CLEC4A	146	Q9UMR7
LAQQESEIAGIENDE	CLTA	36	P09496
QDDEEQGLTAQVLDA	SFT2D1	11	Q8WV19
DDQDEQGNLKGFIND	SUPT6H	46	Q7KZ85
QVDNRLVENFGVQED	TMEM210	81	A6NLX4
QNESLEEQLGQAFDQ	TRAK2	146	O60296
EVQNDGAESAVFQQL	VIL1	331	P09327
QFEQNDLSFVGQDVD	CTPS2	491	Q9NRF8
EDDGKVDFIFEQVQN	SETDB2	16	Q96T68
DFEIQSENGENCNQD	ZSCAN2	136	Q7Z7L9
EENYVLDQDFGLQEN	ZSCAN30	26	Q86W11
GGDEENQEQLQDQIA	WDFY3	2496	Q8IZQ1
ALQQQADEAEDRAQG	TPM4	16	P67936
EEDKENQGDETQGQQ	YBX1	261	P67809
EETGNEVFGALNEEQ	RALGAPA1	776	Q6GYQ0
QEAEEAAQEAEGQTQ	RP1L1	1941	Q8IWN7
EQLLEGYDQQDQDQV	NAPG	236	Q99747
DDGGEDAQSFQQEVI	SCN10A	1011	Q9Y5Y9
GSLDENSDQQVDFQE	S100A2	61	P29034
EEQAQKAIDEVFEGQ	TEX33	161	O43247
IENDGCNVDEGQIEN	ZBTB10	516	Q96DT7
QTDVDNDLVGDQCDN	THBS2	846	P35442
SDGLVNVFDINIDNE	WDR89	191	Q96FK6
SDIQFLEDAGNNVEV	RWDD1	196	Q9H446
EGNEEEIQRENYQDN	TERB1	421	Q8NA31
EAFQRQIFDEDQNDP	TBRG1	346	Q3YBR2
FLSAQELGNEEQQEK	ZRANB1	631	Q9UGI0
VNGQNESNDTEQLDD	ZNF175	211	Q9Y473
EEQRNEFENFVEEQN	UCMA	91	Q8WVF2
LEQFEQAGQAQAELE	GOLGB1	346	Q14789
QEQFDEQSKENENIG	GOLGB1	1216	Q14789