Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionATP-dependent chromatin remodeler activity

BTAF1 ZRANB3 ERCC6L2 HLTF

9.59e-05371304GO:0140658
GeneOntologyMolecularFunctionstructural constituent of skin epidermis

KRT4 KRT5 KRT79 KRT87P

1.74e-04431304GO:0030280
GeneOntologyMolecularFunctionATP-dependent activity

MYH2 SETX DNAH10 MYO5B DYNC2H1 BTAF1 ZRANB3 MDN1 ERCC6L2 HLTF CCT6B MACF1 MYO15A

1.88e-0461413013GO:0140657
GeneOntologyBiologicalProcessintermediate filament cytoskeleton organization

KRT4 KRT5 EVPL KRT79 KRT87P PPL MACF1

2.79e-06991287GO:0045104
GeneOntologyBiologicalProcessintermediate filament-based process

KRT4 KRT5 EVPL KRT79 KRT87P PPL MACF1

2.98e-061001287GO:0045103
GeneOntologyBiologicalProcesscilium assembly

ATMIN DYNC2H1 SDCCAG8 DZIP1L CEP290 DNAAF2 IQCB1 POC1B PKHD1 CFAP70 WDR44 CEP19 IQCG

4.01e-0644412813GO:0060271
GeneOntologyBiologicalProcesscilium organization

ATMIN DYNC2H1 SDCCAG8 DZIP1L CEP290 DNAAF2 IQCB1 POC1B PKHD1 CFAP70 WDR44 CEP19 IQCG

8.49e-0647612813GO:0044782
GeneOntologyBiologicalProcesskeratinization

KRT4 KRT5 EVPL KRT79 KRT87P PPL

1.70e-05871286GO:0031424
GeneOntologyBiologicalProcessciliary transition zone assembly

DZIP1L CEP290

3.82e-0521282GO:1905349
GeneOntologyBiologicalProcessplasma membrane bounded cell projection assembly

ATMIN MYLK DYNC2H1 SDCCAG8 DZIP1L CEP290 DNAAF2 IQCB1 POC1B PKHD1 CFAP70 WDR44 CEP19 IQCG

7.29e-0567012814GO:0120031
GeneOntologyBiologicalProcessorganelle assembly

ATMIN CENPF DYNC2H1 SDCCAG8 DZIP1L CEP290 CSMD2 DNAAF2 LMOD3 MDN1 IQCB1 FAM209B CLTC POC1B PKHD1 CFAP70 WDR44 CEP19 IQCG

7.61e-05113812819GO:0070925
GeneOntologyBiologicalProcesscell projection assembly

ATMIN MYLK DYNC2H1 SDCCAG8 DZIP1L CEP290 DNAAF2 IQCB1 POC1B PKHD1 CFAP70 WDR44 CEP19 IQCG

9.22e-0568512814GO:0030031
GeneOntologyBiologicalProcessmicrotubule-based process

SPATA7 DNAH10 DYNC2H1 SGK1 SDCCAG8 CEP290 CLIP1 STAU1 DNAAF2 MET CLTC POC1B PKHD1 MACF1 CFAP70 TRIM36 CEP19 IQCG

9.46e-05105812818GO:0007017
GeneOntologyBiologicalProcesskeratinocyte differentiation

KRT4 KRT5 EVPL KRT79 KRT87P PPL PRKCH

1.80e-041891287GO:0030216
GeneOntologyBiologicalProcesscytosolic ciliogenesis

IQCB1 WDR44

2.27e-0441282GO:0061824
GeneOntologyCellularComponentciliary basal body

SPATA7 CENPF SDCCAG8 DZIP1L CEP290 DNAAF2 POC1B PKHD1 CFAP70 CEP19

4.00e-0719513010GO:0036064
GeneOntologyCellularComponentintermediate filament cytoskeleton

KRT4 KRT5 EVPL KRT79 KRT87P CLIP1 PPL MDN1 MACF1

4.03e-052631309GO:0045111
GeneOntologyCellularComponentmicrotubule organizing center

SPATA7 PDE4D CENPF SDCCAG8 DZIP1L CEP290 ANKRD62 CLIP1 ITGB6 DNAAF2 IQCB1 POC1B ERCC6L2 PKHD1 LRRCC1 CFAP70 CEP19

5.64e-0591913017GO:0005815
GeneOntologyCellularComponentintermediate filament

KRT4 KRT5 EVPL KRT79 KRT87P CLIP1 PPL MACF1

8.91e-052271308GO:0005882
GeneOntologyCellularComponentcentriole

SDCCAG8 DZIP1L CEP290 IQCB1 POC1B LRRCC1 CEP19

1.02e-041721307GO:0005814
GeneOntologyCellularComponentcilium

SPATA7 DNAH10 CENPF DYNC2H1 SDCCAG8 DZIP1L CEP290 DNAAF2 MET IQCB1 POC1B PKHD1 CFAP70 CEP19 IQCG

4.71e-0489813015GO:0005929
GeneOntologyCellularComponentphotoreceptor distal connecting cilium

SPATA7 CEP290

7.90e-0471302GO:0120206
GeneOntologyCellularComponentactin cytoskeleton

FKBP15 MYH2 MYLK MYO5B ANKRD62 LMOD3 XIRP2 MACF1 ADAM17 MYO15A IQCG

9.55e-0457613011GO:0015629
GeneOntologyCellularComponentcentrosome

PDE4D CENPF SDCCAG8 CEP290 ANKRD62 CLIP1 ITGB6 IQCB1 POC1B ERCC6L2 PKHD1 LRRCC1 CEP19

1.03e-0377013013GO:0005813
GeneOntologyCellularComponentrod photoreceptor outer segment

SPATA7 CEP290

1.34e-0391302GO:0120200
HumanPhenoCongenital hepatic fibrosis

DYNC2H1 SDCCAG8 DZIP1L CEP290 IQCB1 PKHD1

4.05e-0646496HP:0002612
HumanPhenoHepatic fibrosis

DYNC2H1 SDCCAG8 DZIP1L CEP290 CP MET IQCB1 PKHD1 CEP19

1.04e-05151499HP:0001395
HumanPhenoAbnormal renal medulla morphology

DYNC2H1 SDCCAG8 DZIP1L CEP290 IQCB1 PKHD1

2.36e-0562496HP:0100957
MousePhenoabnormal cilium morphology

ATMIN SPATA7 DNAH10 DYNC2H1 SDCCAG8 CEP290 CLIP1 DNAAF2 BRDT POC1B PKHD1 CCT6B CFAP70 IQCG

3.38e-0643310314MP:0013202
MousePhenoabnormal primary cilium morphology

ATMIN SPATA7 DYNC2H1 SDCCAG8 CEP290 DNAAF2 PKHD1

2.07e-051141037MP:0013203
MousePhenoabsent kidney epithelial cell primary cilium

SDCCAG8 CEP290

5.38e-0521032MP:0020384
DomainPlectin

EVPL PPL MACF1

1.08e-0571283PF00681
DomainPlectin_repeat

EVPL PPL MACF1

1.08e-0571283IPR001101
DomainPLEC

EVPL PPL MACF1

1.08e-0571283SM00250
DomainZINC_FINGER_C2H2_2

ATMIN ZNF138 DZIP1L ZNF224 ZFP69 ZNF501 ZNF354B ZFP37 ZNF585B SALL2 ZNF33B ZNF277 ZNF667 ZNF721 ZNF860 ZNF91 ZBTB11

2.21e-0577512817PS50157
DomainZINC_FINGER_C2H2_1

ATMIN ZNF138 DZIP1L ZNF224 ZFP69 ZNF501 ZNF354B ZFP37 ZNF585B SALL2 ZNF33B ZNF277 ZNF667 ZNF721 ZNF860 ZNF91 ZBTB11

2.29e-0577712817PS00028
Domainzf-C2H2_11

ZNF354B ZNF667 ZNF721

2.56e-0591283PF16622
DomainZnf_C2H2-like

ATMIN ZNF138 DZIP1L ZNF224 ZFP69 ZNF501 ZNF354B ZFP37 ZNF585B SALL2 ZNF33B ZNF277 ZNF667 ZNF721 ZNF860 ZNF91 ZBTB11

3.11e-0579612817IPR015880
DomainZnf_C2H2

ATMIN ZNF138 DZIP1L ZNF224 ZFP69 ZNF501 ZNF354B ZFP37 ZNF585B SALL2 ZNF33B ZNF277 ZNF667 ZNF721 ZNF860 ZNF91 ZBTB11

3.58e-0580512817IPR007087
DomainZnF_C2H2

ATMIN ZNF138 DZIP1L ZNF224 ZFP69 ZNF501 ZNF354B ZFP37 ZNF585B SALL2 ZNF33B ZNF277 ZNF667 ZNF721 ZNF860 ZNF91 ZBTB11

3.75e-0580812817SM00355
Domainzf-C2H2_6

ZNF224 ZNF501 ZNF354B ZFP37 SALL2 ZNF667 ZNF721 ZNF860 ZNF91 ZBTB11

6.16e-0531412810PF13912
DomainSNF2_N

BTAF1 ZRANB3 ERCC6L2 HLTF

6.52e-05321284IPR000330
DomainSNF2_N

BTAF1 ZRANB3 ERCC6L2 HLTF

6.52e-05321284PF00176
Domainzf-C2H2

ZNF138 ZNF224 ZFP69 ZNF501 ZNF354B ZFP37 ZNF585B SALL2 ZNF33B ZNF277 ZNF667 ZNF721 ZNF860 ZNF91 ZBTB11

8.11e-0569312815PF00096
DomainATPase_dyneun-rel_AAA

DNAH10 DYNC2H1 MDN1

1.08e-04141283IPR011704
DomainAAA_5

DNAH10 DYNC2H1 MDN1

1.08e-04141283PF07728
DomainIQ

MYH2 MYO5B IQCB1 MYO15A IQCG

1.27e-04711285PF00612
DomainKRAB

POGK ZNF224 ZFP69 ZNF354B ZFP37 ZNF585B ZNF33B ZNF667 ZNF860 ZNF91

1.81e-0435812810PS50805
DomainKRAB

POGK ZNF224 ZFP69 ZNF354B ZFP37 ZNF585B ZNF33B ZNF667 ZNF860 ZNF91

1.81e-0435812810PF01352
DomainKRAB

POGK ZNF224 ZFP69 ZNF354B ZFP37 ZNF585B ZNF33B ZNF667 ZNF860 ZNF91

2.31e-0436912810SM00349
DomainPSI

ITGB6 SEMA4C MET PTTG1IP

2.31e-04441284IPR016201
Domain-

ZNF138 ZNF224 ZFP69 ZNF501 ZNF354B ZFP37 ZNF585B SALL2 ZNF33B ZNF667 ZNF721 ZNF860 ZNF91 ZBTB11

2.34e-04679128143.30.160.60
DomainKRAB

POGK ZNF224 ZFP69 ZNF354B ZFP37 ZNF585B ZNF33B ZNF667 ZNF860 ZNF91

2.36e-0437012810IPR001909
DomainIQ

MYH2 MYO5B IQCB1 MYO15A IQCG

2.36e-04811285SM00015
DomainPSI

ITGB6 SEMA4C MET PTTG1IP

2.75e-04461284SM00423
DomainZnf_C2H2/integrase_DNA-bd

ZNF138 ZNF224 ZFP69 ZNF501 ZNF354B ZFP37 ZNF585B SALL2 ZNF33B ZNF667 ZNF721 ZNF860 ZNF91 ZBTB11

2.93e-0469412814IPR013087
DomainIQ_motif_EF-hand-BS

MYH2 MYO5B IQCB1 MYO15A IQCG

3.86e-04901285IPR000048
DomainIQ

MYH2 MYO5B IQCB1 MYO15A IQCG

4.49e-04931285PS50096
Domain-

EVPL MACF1

6.87e-04612823.90.1290.10
DomainKeratin_II

KRT4 KRT5 KRT79

7.28e-04261283IPR003054
DomainSpectrin_repeat

EVPL PPL MACF1

1.01e-03291283IPR002017
DomainDHC_N1

DNAH10 DYNC2H1

1.27e-0381282PF08385
DomainDynein_heavy_dom-1

DNAH10 DYNC2H1

1.27e-0381282IPR013594
DomainLRRCT

LRRN1 TLR6 ADGRA3

1.35e-03321283PF01463
DomainSPEC

EVPL PPL MACF1

1.35e-03321283SM00150
DomainSpectrin/alpha-actinin

EVPL PPL MACF1

1.35e-03321283IPR018159
DomainP-loop_NTPase

MYH2 SETX DNAH10 MYO5B DYNC2H1 BTAF1 ZRANB3 MDN1 GIMAP8 IQCB1 ERCC6L2 HLTF RAB2B MYO15A

2.03e-0384812814IPR027417
DomainMyosin_head_motor_dom

MYH2 MYO5B MYO15A

2.23e-03381283IPR001609
DomainMYOSIN_MOTOR

MYH2 MYO5B MYO15A

2.23e-03381283PS51456
DomainMyosin_head

MYH2 MYO5B MYO15A

2.23e-03381283PF00063
DomainMYSc

MYH2 MYO5B MYO15A

2.23e-03381283SM00242
DomainDynein_heavy_chain_D4_dom

DNAH10 DYNC2H1

4.02e-03141282IPR024317
DomainDynein_HC_stalk

DNAH10 DYNC2H1

4.02e-03141282IPR024743
DomainDynein_heavy_dom-2

DNAH10 DYNC2H1

4.02e-03141282IPR013602
DomainDHC_N2

DNAH10 DYNC2H1

4.02e-03141282PF08393
DomainMT

DNAH10 DYNC2H1

4.02e-03141282PF12777
DomainAAA_8

DNAH10 DYNC2H1

4.02e-03141282PF12780
DomainDHC_fam

DNAH10 DYNC2H1

4.62e-03151282IPR026983
DomainDynein_heavy

DNAH10 DYNC2H1

4.62e-03151282PF03028
DomainDynein_heavy_dom

DNAH10 DYNC2H1

4.62e-03151282IPR004273
DomainHelicase_C

BTAF1 ZRANB3 ERCC6L2 HLTF

6.31e-031071284PF00271
DomainHELICc

BTAF1 ZRANB3 ERCC6L2 HLTF

6.31e-031071284SM00490
DomainHelicase_C

BTAF1 ZRANB3 ERCC6L2 HLTF

6.52e-031081284IPR001650
DomainHELICASE_CTER

BTAF1 ZRANB3 ERCC6L2 HLTF

6.73e-031091284PS51194
DomainHELICASE_ATP_BIND_1

BTAF1 ZRANB3 ERCC6L2 HLTF

6.73e-031091284PS51192
DomainDEXDc

BTAF1 ZRANB3 ERCC6L2 HLTF

6.73e-031091284SM00487
PathwayWP_CILIOPATHIES

SPATA7 CENPF DYNC2H1 SDCCAG8 CEP290 DNAAF2 IQCB1 POC1B PKHD1 CEP19

8.48e-0718410210M39880
PathwayREACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE

KRT4 KRT5 EVPL KRT79 KRT87P PPL

3.89e-05871026MM15351
Pubmed

Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods.

SDCCAG8 CEP290 CLIP1 IQCB1 POC1B LRRCC1 CEP19

1.59e-06146133721399614
Pubmed

Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.

CALCOCO2 KRT4 KRT5 PDE4D CEP290 KRT79 KRT87P PPP2CA IGF2R IQCB1 MYO15A GOLGB1

1.91e-065641331221565611
Pubmed

Defining the membrane proteome of NK cells.

CALCOCO2 FKBP15 KRT5 ABR ACAA1 CNOT10 CEP290 STAU1 IGF2R MDN1 ARFGAP3 CLTC HLTF ADAM17 MUL1 PTTG1IP GOLGB1

2.47e-0611681331719946888
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

BDP1 KRT5 SETX DYNC2H1 EMSY SALL2 ANAPC1 IQCB1 CLTC MACF1 POLK GOLGB1

2.92e-065881331238580884
Pubmed

Meta-analysis of genome-wide association studies identifies ten loci influencing allergic sensitization.

TLR6 EMSY ANAPC1 TSLP

6.76e-0632133423817571
Pubmed

SPATA7 maintains a novel photoreceptor-specific zone in the distal connecting cilium.

SPATA7 SDCCAG8 CEP290

8.82e-0611133329899041
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

SPATA7 KRT5 SETX AFF2 PPL SEMA4C MET IGF2R ARFGAP3 CLTC PRKCH WDR41 GOLGB1

9.54e-067771331335844135
Pubmed

N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.

KRT4 ACAA1 EVPL BTAF1 EMSY PPL MET MACF1 GOLGB1

1.09e-05360133933111431
Pubmed

Subcellular distribution of envoplakin and periplakin: insights into their role as precursors of the epidermal cornified envelope.

EVPL PPL

1.45e-052133211062259
Pubmed

Treatment Potential for Macular Cone Vision in Leber Congenital Amaurosis Due to CEP290 or NPHP5 Mutations: Predictions From Artificial Intelligence.

CEP290 IQCB1

1.45e-052133231212307
Pubmed

Atmin modulates Pkhd1 expression and may mediate Autosomal Recessive Polycystic Kidney Disease (ARPKD) through altered non-canonical Wnt/Planar Cell Polarity (PCP) signalling.

ATMIN PKHD1

1.45e-052133230414501
Pubmed

Co-assembly of envoplakin and periplakin into oligomers and Ca(2+)-dependent vesicle binding: implications for cornified cell envelope formation in stratified squamous epithelia.

EVPL PPL

1.45e-052133215033990
Pubmed

MYO5B is epigenetically silenced and associated with MET signaling in human gastric cancer.

MYO5B MET

1.45e-052133223456500
Pubmed

Detection of anti-envoplakin and anti-periplakin autoantibodies by ELISA in patients with paraneoplastic pemphigus.

EVPL PPL

1.45e-052133218820940
Pubmed

Genetic and physical interaction between the NPHP5 and NPHP6 gene products.

CEP290 IQCB1

1.45e-052133218723859
Pubmed

Removal of cell surface heparan sulfate increases TACE activity and cleavage of ErbB4 receptor.

ERBB4 ADAM17

1.45e-052133219171023
Pubmed

Allelic variations of human keratins K4 and K5 provide polymorphic markers within the type II keratin gene cluster on chromosome 12.

KRT4 KRT5

1.45e-05213327684424
Pubmed

Interaction of periplakin and envoplakin with intermediate filaments.

EVPL PPL

1.45e-052133212432088
Pubmed

A role for the Golgi matrix protein giantin in ciliogenesis through control of the localization of dynein-2.

DYNC2H1 GOLGB1

1.45e-052133224046448
Pubmed

A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci.

RANBP6 TLR6 EMSY TSLP

2.46e-0544133423817569
Pubmed

Leber Congenital Amaurosis – RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY

SPATA7 CEP290 IQCB1

3.57e-0517133320301475
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

MYO5B DYNC2H1 CP EVPL PPL IGF2R CLTC PKHD1 PRKCH CFAP70 MYO15A CCDC180 PTTG1IP IQCG

3.68e-0510161331419056867
Pubmed

cAMP-stimulated protein phosphatase 2A activity associated with muscle A kinase-anchoring protein (mAKAP) signaling complexes inhibits the phosphorylation and activity of the cAMP-specific phosphodiesterase PDE4D3.

PDE4D PPP2CA

4.34e-053133220106966
Pubmed

Time for remodeling: SNF2-family DNA translocases in replication fork metabolism and human disease.

ZRANB3 HLTF

4.34e-053133232971328
Pubmed

Dissociated presenilin-1 and TACE processing of ErbB4 in lung alveolar type II cell differentiation.

ERBB4 ADAM17

4.34e-053133224462774
Pubmed

Epidermal barrier defects link atopic dermatitis with altered skin cancer susceptibility.

EVPL PPL

4.34e-053133224843010
Pubmed

Human papillomavirus type 16 E6 suppresses microRNA-23b expression in human cervical cancer cells through DNA methylation of the host gene C9orf3.

MET AOPEP

4.34e-053133228077801
Pubmed

Functions of SMARCAL1, ZRANB3, and HLTF in maintaining genome stability.

ZRANB3 HLTF

4.34e-053133228954549
Pubmed

ADAM10/17-dependent release of soluble c-Met correlates with hepatocellular damage.

MET ADAM17

4.34e-053133223746173
Pubmed

Cytokeratin 5/6, c-Met expressions, and PTEN loss prognostic indicators in triple-negative breast cancer.

KRT5 MET

4.34e-053133224326984
Pubmed

Periplakin, a novel component of cornified envelopes and desmosomes that belongs to the plakin family and forms complexes with envoplakin.

EVPL PPL

4.34e-05313329412476
Pubmed

High incidence of ErbB3, ErbB4, and MET expression in ovarian cancer.

ERBB4 MET

4.34e-053133224901400
Pubmed

EMSY is increased and activates TSLP & CCL5 expression in eosinophilic esophagitis.

EMSY TSLP

4.34e-053133229663593
Pubmed

Increased Bacterial Load and Expression of Antimicrobial Peptides in Skin of Barrier-Deficient Mice with Reduced Cancer Susceptibility.

EVPL PPL

4.34e-053133226763429
Pubmed

MET signaling in keratinocytes activates EGFR and initiates squamous carcinogenesis.

MET ADAM17

4.34e-053133227330189
Pubmed

Frequent gene amplification predicts poor prognosis in gastric cancer.

ERBB4 MET

4.34e-053133222606006
Pubmed

Cone photoreceptors are the main targets for gene therapy of NPHP5 (IQCB1) or NPHP6 (CEP290) blindness: generation of an all-cone Nphp6 hypomorph mouse that mimics the human retinal ciliopathy.

CEP290 IQCB1

4.34e-053133221245082
Pubmed

WDR76 is a RAS binding protein that functions as a tumor suppressor via RAS degradation.

PDE4D ABR TLR6 ANAPC1

4.80e-0552133430655611
Pubmed

Analysis of interaction partners for eukaryotic translation elongation factor 1A M-domain by functional proteomics.

ANKRD62 XIRP2 MACF1

5.94e-0520133321689717
Pubmed

Nephronophthisis-Related Ciliopathies

SDCCAG8 CEP290 IQCB1

6.91e-0521133327336129
Pubmed

Intersectin (ITSN) family of scaffolds function as molecular hubs in protein interaction networks.

PDE4D KRT79 PPL CLTC GOLGB1

7.02e-05111133522558309
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

SETX DZIP1L DHDDS ITGA9 ZRANB3 ZFP37 IGF2R AOPEP TET1 CLTC MACF1 ADAM17 POLK GOLGB1

7.37e-0510841331411544199
Pubmed

Exome sequencing in seven families and gene-based association studies indicate genetic heterogeneity and suggest possible candidates for fibromuscular dysplasia.

MYLK DYNC2H1

8.67e-054133226147384
Pubmed

Smooth muscle myosin light chain kinase expression in cardiac and skeletal muscle.

MYH2 MYLK

8.67e-054133211029314
Pubmed

Allergy and glioma risk: test of association by genotype.

PDE4D EMSY

8.67e-054133220503266
Pubmed

Cilia and polycystic kidney disease.

DZIP1L PKHD1

8.67e-054133232475690
Pubmed

Self-control of HGF regulation on human trophoblast cell invasion via enhancing c-Met receptor shedding by ADAM10 and ADAM17.

MET ADAM17

8.67e-054133222689693
Pubmed

ATP-mediated transactivation of the epidermal growth factor receptor in airway epithelial cells involves DUOX1-dependent oxidation of Src and ADAM17.

DUOX1 ADAM17

8.67e-054133223349873
Pubmed

Galectin-6 is a novel skin anti-microbial peptide that is modulated by the skin barrier and microbiome.

EVPL PPL

8.67e-054133227427436
Pubmed

New consensus nomenclature for mammalian keratins.

KRT4 KRT5 KRT79 KRT87P

1.02e-0463133416831889
Pubmed

A human MAP kinase interactome.

KRT5 SETX CEP290 EVPL CLTC MACF1 PRKCH GOLGB1 WDR44

1.11e-04486133920936779
Pubmed

Leber Congenital Amaurosis / Early-Onset Severe Retinal Dystrophy Overview

SPATA7 CEP290 IQCB1

1.18e-0425133330285347
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

LRRN1 MYO5B DYNC2H1 CEP290 ANKRD62 REXO1 SEMA4C LRRCC1 MACF1

1.24e-04493133915368895
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

MYH2 KRT5 MYLK MYO5B CENPF DZIP1L KRT79 PPL LMOD3 PPP2CA MDN1 CLTC PKHD1 MACF1 ZBTB11 GOLGB1

1.31e-0414421331635575683
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

KRT5 PDE4D BTAF1 ANAPC1 CLTC MROH7

1.32e-04202133633005030
Pubmed

Role of CLASP2 in microtubule stabilization and the regulation of persistent motility.

CLIP1 MACF1

1.44e-045133217113391
Pubmed

SHPRH and HLTF act in a damage-specific manner to coordinate different forms of postreplication repair and prevent mutagenesis.

HLTF POLK

1.44e-045133221396873
Pubmed

Soluble M6P/IGF2R released by TACE controls angiogenesis via blocking plasminogen activation.

IGF2R ADAM17

1.44e-045133221273553
Pubmed

Pathogenic NPHP5 mutations impair protein interaction with Cep290, a prerequisite for ciliogenesis.

CEP290 IQCB1

1.44e-045133223446637
Pubmed

Restoration of Replication Fork Stability in BRCA1- and BRCA2-Deficient Cells by Inactivation of SNF2-Family Fork Remodelers.

ZRANB3 HLTF

1.44e-045133229053959
Pubmed

USP9X counteracts differential ubiquitination of NPHP5 by MARCH7 and BBS11 to regulate ciliogenesis.

CEP290 IQCB1

1.44e-045133228498859
Pubmed

The ERBB4/HER4 receptor tyrosine kinase regulates gene expression by functioning as a STAT5A nuclear chaperone.

ERBB4 ADAM17

1.44e-045133215534001
Pubmed

Binding of GGA2 to the lysosomal enzyme sorting motif of the mannose 6-phosphate receptor.

IGF2R CLTC

1.44e-045133211387476
Pubmed

Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.

AFF2 CLIP1 PPL PHF3 PKHD1 GOLGB1

1.55e-04208133633230847
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

BTAF1 ZNF224 CLIP1 REXO1 EMSY PPL MDN1 ANAPC1 PHF3 CLTC WDR44

2.00e-047741331115302935
Pubmed

Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development.

PDE4D MDN1 MACF1 GOLGB1

2.12e-0476133427542412
Pubmed

Unique role for the periplakin tail in intermediate filament association: specific binding to keratin 8 and vimentin.

EVPL PPL

2.16e-046133212366696
Pubmed

Deubiquitylase USP9X maintains centriolar satellite integrity by stabilizing pericentriolar material 1 protein.

CEP290 IQCB1

2.16e-046133230584065
Pubmed

The gene mutated in cocoa mice, carrying a defect of organelle biogenesis, is a homologue of the human Hermansky-Pudlak syndrome-3 gene.

CP HLTF

2.16e-046133211707070
Pubmed

Ciliopathy-associated protein CEP290 modifies the severity of retinal degeneration due to loss of RPGR.

CEP290 IQCB1

2.16e-046133226936822
Pubmed

Three human RNA polymerase III-specific subunits form a subcomplex with a selective function in specific transcription initiation.

BDP1 POLR3F

2.16e-04613329171375
Pubmed

GWAS identifies four novel eosinophilic esophagitis loci.

EMSY TSLP

2.16e-046133225407941
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

DYNC2H1 RANBP6 BTAF1 CLIP1 SEMA4C MET IGF2R MDN1 MACF1 ADAM17 MUL1 GOLGB1 ADGRA3

2.25e-0410611331333845483
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

ACAA1 AFF2 DYNC2H1 CP KRT79 STAU1 DUOX1 MDN1 CLTC MACF1 MYO15A

2.85e-048071331130575818
Pubmed

Elucidation of the BMI1 interactome identifies novel regulatory roles in glioblastoma.

ACAA1 EVPL BTAF1 KRT79 POLR3F CLTC POC1B

2.86e-04329133734316702
Pubmed

Niche-Specific Factors Dynamically Regulate Sebaceous Gland Stem Cells in the Skin.

KRT79 TSLP

3.01e-047133231564613
Pubmed

Serum and glucocorticoid-inducible kinase (SGK) is a target of the PI 3-kinase-stimulated signaling pathway.

SGK1 PPP2CA

3.01e-047133210357815
Pubmed

Arf4 is required for Mammalian development but dispensable for ciliary assembly.

PKHD1 GOLGB1

3.01e-047133224586199
Pubmed

Differential effects of the integrins alpha9beta1, alphavbeta3, and alphavbeta6 on cell proliferative responses to tenascin. Roles of the beta subunit extracellular and cytoplasmic domains.

ITGA9 ITGB6

3.01e-04713328798654
Pubmed

Pathway-based association analysis of genome-wide screening data suggest that genes associated with the gamma-aminobutyric acid receptor signaling pathway are involved in neuroleptic-induced, treatment-resistant tardive dyskinesia.

SLC6A11 GABRA4

4.00e-048133218334916
Pubmed

Distinct structural requirements for binding of the integrins alphavbeta6, alphavbeta3, alphavbeta5, alpha5beta1 and alpha9beta1 to osteopontin.

ITGA9 ITGB6

4.00e-048133216005200
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

KRT5 SDCCAG8 CEP290 CP CLIP1 EMSY IGF2R ARFGAP3 CCT6B LRRCC1 FHL1

4.54e-048531331128718761
Pubmed

F-box only protein 9 is an E3 ubiquitin ligase of PPARγ.

ITGA9 ZRANB3 DUOX1

4.87e-0440133327197753
Pubmed

Novel activity of KRAB domain that functions to reinforce nuclear localization of KRAB-containing zinc finger proteins by interacting with KAP1.

ZNF224 ZNF91

5.13e-049133223665872
Pubmed

BRAF activates PAX3 to control muscle precursor cell migration during forelimb muscle development.

MYH2 MET

5.13e-049133227906130
Pubmed

RUNX1 marks a luminal castration-resistant lineage established at the onset of prostate development.

KRT4 KRT5

5.13e-049133233025905
Pubmed

Mulan E3 ubiquitin ligase interacts with multiple E2 conjugating enzymes and participates in mitophagy by recruiting GABARAP.

RNF14 MUL1

5.13e-049133225224329
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

FKBP15 CEP290 STAU1 IGF2R ANAPC1 PHF3 ARFGAP3 IQCB1 WDR41 IQCG

5.37e-047331331034672954
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

SETX CENPF CEP290 EVPL CSMD2 MDN1 GIMAP8 CLTC PKHD1 ZBTB11

5.54e-047361331029676528
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

SETX CNOT10 CREB3L4 EMSY SEMA4C PPP2CA MDN1 ANAPC1 ZNF277 PHF3 ARFGAP3 HLTF MACF1 ZBTB11 GOLGB1

6.25e-0414971331531527615
Pubmed

Single-cell transcriptomics reveals the cellular identity of a novel progenitor population crucial for murine neural tube closure.

KRT5 TSLP

6.40e-0410133239296075
Pubmed

Two Ancient Gene Families Are Critical for Maintenance of the Mammalian Skin Barrier in Postnatal Life.

KRT5 TSLP

6.40e-0410133226975724
Pubmed

The Foxn1-dependent transcripts PCOLCE2 and mPPP1R16B are not required for normal thymopoiesis.

KRT4 KRT5

6.40e-0410133217683113
Pubmed

Developmental origin and morphogenesis of the diaphragm, an essential mammalian muscle.

MYH2 MET

6.40e-0410133229679560
Pubmed

Functional analysis of the SRY-KRAB interaction in mouse sex determination.

ZNF721 ZNF91

6.40e-0410133218588511
Pubmed

ACF7 regulates cytoskeletal-focal adhesion dynamics and migration and has ATPase activity.

CLIP1 MACF1

6.40e-0410133218854161
Pubmed

Immunolocalization patterns of cytokeratins during salivary acinar cell development in mice.

KRT4 KRT5

6.40e-0410133229181608
Pubmed

TRAIL deficiency and PP2A activation with salmeterol ameliorates egg allergen-driven eosinophilic esophagitis.

PPP2CA TSLP

6.40e-0410133227742702
Pubmed

Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.

SETX MYO5B BTAF1 MDN1 ANAPC1 CLTC

6.48e-04272133631010829
Pubmed

Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

BDP1 SEMA4C TET1 LRRCC1

6.50e-04102133411214970
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ATMIN ZNF138 ZNF224 ZFP69 ZNF501 ZNF354B ZFP37 ZNF585B SALL2 ZNF33B ZNF667 ZNF721 ZNF860 ZNF91 ZBTB11

3.65e-06718931528
GeneFamilyEF-hand domain containing|Plakins

EVPL PPL MACF1

7.24e-068933939
GeneFamilyKeratins, type II

KRT4 KRT5 KRT79

3.52e-0427933609
CoexpressionTERAO_AOX4_TARGETS_SKIN_DN

FKBP15 ZNF354B ZNF721 CFAP70 ZNF91

2.59e-07281315MM925
CoexpressionGSE45739_NRAS_KO_VS_WT_ACD3_ACD28_STIM_CD4_TCELL_DN

ZNF138 CENPF SGK1 CREB3L4 DACT1 ZNF33B PKHD1 IQCG

7.20e-061981318M9882
CoexpressionAtlasFacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_1000_k-means-cluster#3

SPATA7 BDP1 AFF2 CENPF CEP290 CLIP1 EMSY ZFP37 POC1B MACF1 ZNF91

1.69e-0629112911Facebase_RNAseq_e10.5_Lateral Nasal Eminence_1000_K3
CoexpressionAtlasFacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_2500_k-means-cluster#1

SPATA7 BDP1 CENPF CEP290 CLIP1 EMSY ZFP37 RNF14 TET1 POC1B ERCC6L2 FNIP1 MACF1 ZNF91 FHL1 POLK

2.09e-0578012916Facebase_RNAseq_e10.5_Lateral Nasal Eminence_2500_K1
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500

BDP1 ERBB4 SETX AFF2 LRRN1 CENPF CEP290 BTAF1 ZFP69 CLIP1 EMSY ZRANB3 POLR3F MDN1 PHF3 IQCB1 TET1 POC1B LRRCC1 MACF1 CLEC10A FHL1

6.52e-05145912922facebase_RNAseq_e10.5_Emin_LatNas_2500
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500_K3

BDP1 SETX LRRN1 CENPF CEP290 BTAF1 ZFP69 CLIP1 EMSY ZRANB3 POLR3F MDN1 PHF3 IQCB1 TET1 POC1B LRRCC1 MACF1 CLEC10A FHL1

7.05e-05125712920facebase_RNAseq_e10.5_Emin_LatNas_2500_K3
CoexpressionAtlasFacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_1000_k-means-cluster#4

SPATA7 BDP1 PDE4D SETX CEP290 ZFP69 LRRCC1 MACF1 GOLGB1

8.81e-052981299Facebase_RNAseq_e10.5_Medial Nasal Eminence_1000_K4
ToppCellCOPD-Epithelial-Club|COPD / Disease state, Lineage and Cell class

ERBB4 MYO5B AGR3 CP ITGA9 ITGB6 PPL MET RNASE1 ADGRA3

3.22e-1019113310c909cf5fa0e6519aa93a47d2c3fcd2ae2163cd8d
ToppCellCOPD-Epithelial-Club|World / Disease state, Lineage and Cell class

ERBB4 MYO5B AGR3 ITGA9 ITGB6 PPL MET ADGRA3

9.25e-0818613383006f4ab1eaf1eb34c10ca9f7c869603d2d25744
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ERBB4 MYO5B AGR3 EVPL PPL MET PKHD1 CFAP70

1.13e-07191133860ff989fe99d243a3d52955223680cdd1f1917a4
ToppCellBronchial-10x5prime-Epithelial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

KRT5 MYO5B AGR3 CP ITGB6 PPL MET DUOX1

1.61e-072001338d3ee5f79513e2ac02ad3329b59e6290d457c44d2
ToppCellBiopsy_Other_PF-Epithelial-SCGB3A2+|Biopsy_Other_PF / Sample group, Lineage and Cell type

KRT4 AGR3 CP EVPL ITGB6 PPL MET RNASE1

1.61e-072001338631550dc34bcb605ab726645f4024d7828bb7975
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYO5B AGR3 CP ITGA9 ITGB6 PPL PKHD1

1.33e-061831337ff6dde877659cde9daa3263db0932c9c9ef1adac
ToppCellEpithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|World / Lineage, Cell type, age group and donor

ERBB4 PDE4D AGR3 CP ITGA9 ITGB6 MET

1.53e-06187133781cc8435b2704a9a8287b3f54acaae0f11dd4ac7
ToppCellEpithelial-Epithelial-D_(Ciliated)|Epithelial / shred on cell class and cell subclass (v4)

DNAH10 DYNC2H1 CEP290 AGR3 CFAP70 CCDC180 IQCG

1.59e-0618813378f30535a32968a81a304315a49c0d90a77d36948
ToppCellCOVID-19-Epithelial_cells|COVID-19 / group, cell type (main and fine annotations)

ERBB4 PDE4D MYO5B AGR3 ITGB6 MET DUOX1

1.59e-061881337c9cdee6f8d42ee69f5fb335f25084603c511bd29
ToppCellControl-Epithelial_cells|Control / group, cell type (main and fine annotations)

ERBB4 PDE4D MYO5B AGR3 ITGB6 MET DUOX1

1.59e-061881337707ebf76cc6fb600b2f07793cf4ea9482c0de79d
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ERBB4 PDE4D DYNC2H1 ITGB6 MET PKHD1 HMGCLL1

1.64e-061891337e32172ad09e93f6ac6ea2b92145b2b73003f7970
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ERBB4 ITGB6 PPL MET AOPEP PKHD1 ADGRA3

1.89e-061931337f42a0f02ed00fe1bb833ff0a0640d9131bca89bd
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_neural-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CALCOCO2 SPATA7 DNAH10 CSMD2 CREB3L4 FARS2 HMGCLL1

1.89e-061931337088c8b1e968f5356502347eaabdc6b1b1d4befd0
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ERBB4 ITGB6 PPL MET AOPEP PKHD1 ADGRA3

1.89e-06193133742df7ed37d11fb542b4d1d714b6f87ae8e1396a6
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ERBB4 ITGB6 PPL MET AOPEP PKHD1 ADGRA3

1.96e-061941337e577d9e88390b36b5a09b97fe1026089892275a3
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ERBB4 PDE4D MYO5B ITGB6 MET AOPEP PKHD1

1.96e-0619413377002937e8903e037332a215d00fbc7c7843b33f2
ToppCellnucseq-Epithelial|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ERBB4 PDE4D MYO5B AGR3 ITGB6 DUOX1 AOPEP

2.02e-0619513379406866f99555198a9be311fbd65751b70f35446
ToppCellNS-control-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH10 DYNC2H1 DZIP1L AGR3 CFAP70 CCDC180 IQCG

2.09e-061961337d46ab80554dd3c1cc81e1938ea2acfd5e85c6d2a
ToppCellLAM-Epithelial|LAM / Condition, Lineage and Cell class

PDE4D AGR3 ITGB6 MET DUOX1 RNASE1 C11orf96

2.17e-061971337e5cf07061f6d9db7f12ac17209b267373fa2270b
ToppCellcontrol-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAH10 DYNC2H1 DZIP1L AGR3 CFAP70 CCDC180 IQCG

2.17e-061971337e453d085182364ca347cbcc9dc995c62c3353016
ToppCellSevere_COVID-19-Epithelial-transitional_Epi|Severe_COVID-19 / Disease group,lineage and cell class (2021.01.30)

KRT4 MYO5B DYNC2H1 AGR3 CP PPL MET

2.17e-0619713375ad3cd4c77016e862041baac3076f8cc0f75c417
ToppCellcontrol-Epithelial-Ciliated|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAH10 DYNC2H1 DZIP1L AGR3 CFAP70 CCDC180 IQCG

2.17e-061971337d4e963c1f82996371bf3d63578ee9fce8e00c5a8
ToppCellAT2_cells|World / lung cells shred on cell class, cell subclass, sample id

PDE4D AGR3 ITGB6 MET DUOX1 RNASE1 C11orf96

2.24e-06198133792c569c3b8a9fca2d4682cbf77ee8149bcc0a80a
ToppCellAT2_cells-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

PDE4D MYLK AGR3 MET DUOX1 RNASE1 C11orf96

2.24e-0619813378a1f984e46f4fa5be33027b9dbaa2ca060a2245d
ToppCellASK428-Epithelial-Type_2|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

PDE4D AGR3 ITGB6 MET DUOX1 RNASE1 C11orf96

2.24e-061981337ec0d1801363adb70c6a26655b79d12b438c7417d
ToppCellParenchymal-10x5prime-Epithelial-Epi_alveolar-AT1|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MYO5B AGR3 EVPL ITGB6 PPL DUOX1 RNASE1

2.32e-061991337aca81a879ef9c196bd1885eff4c63ffe6c9682b7
ToppCellEpithelial_cells|World / lung cells shred on cell class, cell subclass, sample id

PDE4D AGR3 ITGB6 MET DUOX1 RNASE1 C11orf96

2.32e-061991337bbe69e44b7970f57628365ae771790f2b13d0cae
ToppCellBiopsy_Control_(H.)-Epithelial-Transitional_AT2|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

AGR3 EVPL ITGB6 PPL MET DUOX1 RNASE1

2.32e-061991337e04a57a55c724091db353e2b3baf84372d788728
ToppCelldistal-Epithelial-Club|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

KRT4 AGR3 CP EVPL ITGB6 MET RNASE1

2.32e-061991337c63ccce1285352927fd8c4f7374ec5fff8d70cec
ToppCellBronchus_Control_(B.)-Epithelial-TX-Ciliated|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

DNAH10 DYNC2H1 DZIP1L AGR3 CFAP70 CCDC180 IQCG

2.39e-0620013376a2ccc71a0cbe04a542c379b28b5006de53981c3
ToppCellASK440-Epithelial|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

AGR3 CP ITGB6 MET DUOX1 RNASE1 CFAP70

2.39e-062001337cb617e2a0ca82b470b473b8d5906bc8879c85718
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH2 ERBB4 SLC6A11 OTOGL PKHD1 MYO15A

4.95e-06145133696712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCellwk_15-18-Epithelial-Proximal_epithelial-basal_intermediate_|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

KRT4 KRT5 DUOX1 AOPEP MROH7 GABRA4

8.09e-06158133698712ed7e8e65e8c5ff9318cf0e0a04e271a055d
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ERBB4 MYO5B ITGB6 SLC6A11 DUOX1 PKHD1

8.39e-061591336e6ff9d2bce62bf9ea173af80b688eeb40fa4ea4c
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MYH2 ERBB4 DNAH10 SLC6A11 OTOGL PKHD1

9.34e-061621336bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellE16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CALCOCO2 DNAH10 AGR3 CFAP70 CCDC180 IQCG

1.15e-051681336fa7c0303918cea04e3f4c4f3cb079be19004d214
ToppCellE16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CALCOCO2 DNAH10 AGR3 CFAP70 CCDC180 IQCG

1.15e-0516813367edcab103c69e928d5c19a0d218ffb3ae32f9e70
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D231|Adult / Lineage, Cell type, age group and donor

ERBB4 AGR3 ITGA9 ITGB6 MET ADGRA3

1.23e-051701336269dee5abca9f6aa079f116f0d8f1d198604d9d4
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AGR3 CP ITGB6 MET RNASE1 C11orf96

1.27e-051711336fd59ac4a39748840b2ee1c930ea475433ff61485
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2-Transitional_Club-AT2_L.0.4.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AGR3 CP ITGB6 MET RNASE1 C11orf96

1.27e-051711336d5960b40ad5b87aaa00c93a6b31cdf41cc4f1375
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-epithelial_cell_of_lung|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AGR3 CP ITGB6 MET RNASE1 C11orf96

1.27e-051711336d382430e5cdd0f2aac4fc093d8fe8d66efb4629b
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AGR3 CP ITGB6 MET RNASE1 C11orf96

1.27e-0517113364347e6f62c04ea43299893ad4b79719049009a56
ToppCellwk_20-22-Epithelial-Proximal_epithelial-Deuterosomal|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

DNAH10 MYO5B DUOX1 CFAP70 CCDC180 IQCG

1.27e-05171133652aec5f6677fe2f7a36fb5b18117a4cffaeff58f
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D122|Adult / Lineage, Cell type, age group and donor

ERBB4 AGR3 CP ITGA9 MET DUOX1

1.50e-0517613363fee8a367bb9755aca1b7fcc968b08e51b6e9436
ToppCellAdult-Epithelial-club_cell-D175|Adult / Lineage, Cell type, age group and donor

LRRN1 AGR3 CP ITGA9 MET ADGRA3

1.54e-051771336d652b7d84fe6aa38319d8d5adc72c70441bd0088
ToppCell390C-Epithelial_cells-Epithelial-B_(AT2)|390C / Donor, Lineage, Cell class and subclass (all cells)

ERBB4 AGR3 ITGB6 DUOX1 RNASE1 C11orf96

1.65e-051791336466da2bc3bfc534ffe111c8c28ece7a3cfa08051
ToppCell390C-Epithelial_cells-Epithelial-B_(AT2)-|390C / Donor, Lineage, Cell class and subclass (all cells)

ERBB4 AGR3 ITGB6 DUOX1 RNASE1 C11orf96

1.65e-051791336f4bdebb77d39e63160fbf3a85a340ce4d52b7cfd
ToppCellCOPD-Epithelial-Basal|World / Disease state, Lineage and Cell class

KRT4 KRT5 ITGB6 PPL MET ADGRA3

1.75e-0518113366d8a886b4afe729f8a05b9c0f4ea9375de735da4
ToppCellControl-Epithelial_cells-Airway_club|Control / group, cell type (main and fine annotations)

ERBB4 PDE4D AGR3 CP ITGA9 MET

1.75e-051811336c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCellE18.5-samps-Mesenchymal-Matrix_fibroblast|E18.5-samps / Age Group, Lineage, Cell class and subclass

MYLK CP IGF2R MACF1 FHL1 TSLP

1.81e-051821336ceb37c214662a48efb56ab0d015977c6fab478b0
ToppCellwk_15-18-Epithelial-Proximal_epithelial-Deuterosomal|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

DNAH10 MYO5B AGR3 DUOX1 CCDC180 IQCG

1.81e-051821336000eca5baa6eb2335a1e6d76a13fff5382b0e150
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

KRT4 ERBB4 AGR3 CP ITGA9 MET

1.81e-051821336215c303df42f13597b2c7a95cb157c6bc7aca9a1
ToppCellCOPD-Epithelial-Basal|COPD / Disease state, Lineage and Cell class

KRT4 KRT5 ITGB6 PPL MET ADGRA3

1.86e-0518313360f760e393edc91009bf6c7e02eeac039a1dfb4ed
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-AT2_Progenitor|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYO5B AGR3 CP ITGA9 ITGB6 PPL

1.92e-0518413367cc5796557379c3d1db078c1aeda40659c6e401c
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-AT1-AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYO5B AGR3 CP ITGA9 ITGB6 PKHD1

1.98e-0518513363bef59cc0aa939d2a7e52f0f6c61bc00528fe50b
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Adult / Lineage, Cell type, age group and donor

ERBB4 AGR3 CP ITGA9 ITGB6 MET

1.98e-051851336673f0c688ae6984bc8027df2da335787924f4137
ToppCellCOVID-19-Epithelial_cells-Airway_club|COVID-19 / group, cell type (main and fine annotations)

ERBB4 PDE4D CP ITGA9 MET DUOX1

1.98e-051851336cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ERBB4 DNAH10 DYNC2H1 DZIP1L CFAP70 CCDC180

1.98e-0518513365e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCellControl-Epithelial-Club|World / Disease state, Lineage and Cell class

ERBB4 MYO5B AGR3 ITGA9 MET ADGRA3

2.04e-0518613369798428691408e17ff2af2fe2d1b345f074d67e4
ToppCellfacs-Lung-EPCAM-3m-Epithelial-Ciliated_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 DZIP1L AGR3 CFAP70 CCDC180 IQCG

2.11e-05187133604dba2ed09ee4180830bdf0191921696697ea234
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ERBB4 MYO5B ITGB6 PPL MET PKHD1

2.11e-05187133687b3d0478693d4c54ff06b74e5903036b9c1ee6a
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ERBB4 PDE4D ITGB6 MET DUOX1 PKHD1

2.11e-0518713365df9e1f5ca32217af255e76e6fb5afa346337811
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ERBB4 MYO5B ITGB6 PPL MET PKHD1

2.11e-05187133642a1267bfc27b4460b8409ada580a87c4385841c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ERBB4 MYO5B ITGB6 PPL MET PKHD1

2.11e-05187133664afdea159f5e67a1e5cea35ce898aae6e80aea5
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYO5B CP ITGA9 ITGB6 PPL PKHD1

2.11e-05187133658d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCellLPS_only-Epithelial_alveolar-AT_1|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYO5B AGR3 CP ITGA9 ITGB6 PKHD1

2.11e-051871336ff26a533d310126521efe1d05cf8b9d32e524550
ToppCellfacs-Lung-EPCAM-3m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 DZIP1L AGR3 CFAP70 CCDC180 IQCG

2.11e-051871336805dafe22f835ece4dd091d8030d0a63b52a48dd
ToppCellPCW_13-14-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ERBB4 EVPL ITGB6 PPL RNASE1 PKHD1

2.17e-0518813360d86044bc340e3efb90d0022dd299873639d831c
ToppCellmild-Myeloid-Immature_Neutrophils_1|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

PDE4D AFF2 DNAH10 DZIP1L ITGA9 CLEC12A

2.24e-05189133694dd5d4d815449feff7ce157fe7f8234f7c81422
ToppCellCOVID-19-lung-AT2|COVID-19 / Disease (COVID-19 only), tissue and cell type

ERBB4 PDE4D AGR3 ITGB6 MET DUOX1

2.30e-05190133627a1a86620fe9b5ee930d388b32352206485e6d0
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-alveolar_fibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MYLK CP AOPEP C11orf96 MACF1 FHL1

2.37e-051911336509230f50568e5a8ecf08edc4d58f9e2aa96efe9
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDE4D AFF2 MYLK MET AOPEP PKHD1

2.37e-0519113361cb02007adb344f17ef73d58890f91298c7cf5a1
ToppCellEpithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|World / Lineage, Cell type, age group and donor

ERBB4 PDE4D MYO5B ITGB6 MET PKHD1

2.37e-051911336d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCellChildren_(3_yrs)-Epithelial|Children_(3_yrs) / Lineage, Cell type, age group and donor

ERBB4 PDE4D MYO5B ITGB6 MET DUOX1

2.37e-051911336e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MYLK CP AOPEP C11orf96 MACF1 FHL1

2.37e-0519113360b3dbbc35d9970d3c749aef16dda59886b960e3d
ToppCellEpithelial|World / Lineage, Cell type, age group and donor

ERBB4 PDE4D MYO5B ITGB6 MET DUOX1

2.44e-051921336499e8893afea5e6d3371e0bd018f7e86a524d669
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ERBB4 PDE4D CLIP1 ITGB6 PPL MET

2.44e-051921336f7e7491426bbd6ed29a465b58bf67acb93dbb90a
ToppCellControl-Epithelial-Club|Control / Disease state, Lineage and Cell class

ERBB4 MYO5B AGR3 ITGA9 MET ADGRA3

2.44e-051921336d84ed1ea4a03edaa18c804f75afb03bd7b1f0e16
ToppCellCiliated-cil-3|World / Class top

DNAH10 DYNC2H1 CFAP70 FHL1 CCDC180 IQCG

2.44e-0519213364989ebb8812b8af1870599acd932849122c05a29
ToppCellAdult-Epithelial|Adult / Lineage, Cell type, age group and donor

ERBB4 PDE4D MYO5B ITGB6 MET DUOX1

2.44e-051921336efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ERBB4 PDE4D AGR3 ITGB6 MET DUOX1

2.52e-051931336fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCellnormal_Lung-Epithelial_cells-AT2|normal_Lung / Location, Cell class and cell subclass

AGR3 ITGB6 MET DUOX1 RNASE1 C11orf96

2.52e-05193133680ad1bdc50ecb8a50362f718248441cae20904a6
ToppCellASK440-Epithelial-Secretory|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

KRT4 KRT5 CP PPL MET ZNF667

2.52e-05193133650e98d91697c7af6a3de39e52edde6dd2b67b512
ToppCellAT2_cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

PDE4D MYLK ITGB6 MET DUOX1 RNASE1

2.52e-0519313368187f976fd2d11fad3286690f1a046e894772220
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ERBB4 PDE4D AGR3 ITGB6 MET DUOX1

2.52e-051931336f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCellnucseq-Epithelial-Epithelial_Alveolar|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ERBB4 PDE4D MYO5B AGR3 ITGB6 DUOX1

2.59e-05194133653f3e49e91b1096f3226010e2de767efb490dfe4
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ERBB4 PDE4D MYO5B ITGB6 MET PKHD1

2.59e-0519413365eaaa81f4b2535f983c424aaef00077089526a5c
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ERBB4 MYO5B AGR3 PPL MET PKHD1

2.59e-051941336f95c8dc242c9aebcadfe61b1ed033349cb7e5a88
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH10 DYNC2H1 DZIP1L CFAP70 CCDC180 IQCG

2.59e-0519413364a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCellIPF-Multiplet-Multiplet|IPF / Disease state, Lineage and Cell class

ERBB4 PDE4D DNAH10 DYNC2H1 AGR3 CFAP70

2.67e-051951336fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCellnormal_Lung-Epithelial_cells|normal_Lung / Location, Cell class and cell subclass

AGR3 ITGB6 MET DUOX1 RNASE1 C11orf96

2.67e-0519513367c90d887afde5c4d63352b5171be9987e2dfca58
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ERBB4 PDE4D MYO5B ITGB6 PKHD1 ADGRA3

2.67e-0519513366477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCellIPF-Multiplet|IPF / Disease state, Lineage and Cell class

ERBB4 PDE4D DNAH10 DYNC2H1 AGR3 CFAP70

2.67e-051951336eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCellmoderate-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAH10 DYNC2H1 DZIP1L CFAP70 CCDC180 IQCG

2.67e-0519513363486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCellmoderate-Epithelial-Ciliated|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAH10 DYNC2H1 DZIP1L AGR3 CFAP70 CCDC180

2.67e-051951336e80f5cdf0b18066b3e6c2f5452e58f101c67932c
ToppCellCOVID-19-Epithelial-Ciliated_cells|Epithelial / Condition, Lineage and Cell class

DNAH10 DYNC2H1 DZIP1L CFAP70 CCDC180 IQCG

2.74e-051961336de7aa31354b019d7321a8ef965d59ce2e8b89276
ToppCellE17.5-Mesenchymal|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MYLK CP C11orf96 MACF1 FHL1 TSLP

2.74e-051961336b4ee991445b612506372b9361ebfe72cb59b811e
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PDE4D MYLK ITGB6 DUOX1 RNASE1 C11orf96

2.74e-05196133682b117be41f2e7d677a42d2a5198726eeccb16d0
ToppCellASK440-Epithelial-Type_2|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

PDE4D ITGB6 MET DUOX1 RNASE1 C11orf96

2.74e-051961336754b4202b617165c6994a0b5a9b1e486dccdd44d
ToppCellcritical-Epithelial-Ciliated|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAH10 DYNC2H1 DZIP1L CFAP70 CCDC180 IQCG

2.74e-05196133627b855c6e1ae44f16db998cf0e81bd686b9cee7e
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

BDP1 SETX PHF3 MACF1 GOLGB1

1.78e-0549725GAVISH_3CA_METAPROGRAM_CD8_T_CELLS_CHROMATIN
DrugClorgyline

BDP1 ZNF138 DYNC2H1 CEP290 CLIP1 PHF3 ZNF721 POLK GOLGB1

5.37e-071681309ctd:D003010
DiseaseRenal dysplasia and retinal aplasia (disorder)

SDCCAG8 CEP290 IQCB1 POC1B

1.53e-07121264C0403553
DiseaseCiliopathies

SPATA7 DYNC2H1 SDCCAG8 CEP290 DNAAF2 IQCB1 PKHD1

4.84e-071101267C4277690
DiseaseSenior-Loken syndrome (is_implicated_in)

SDCCAG8 CEP290 IQCB1

2.63e-0671263DOID:0050576 (is_implicated_in)
DiseaseRenal dysplasia and retinal aplasia

SDCCAG8 CEP290 IQCB1

2.63e-0671263cv:C0403553
DiseaseAutosomal recessive polycystic kidney disease

DZIP1L PKHD1

1.81e-0521262cv:C0085548
DiseaseLeber Congenital Amaurosis

SPATA7 CEP290 IQCB1

1.10e-04221263C0339527
Diseaseloneliness measurement

ERBB4 STAU1 SLC6A11 EXD3 MACF1

1.97e-041241265EFO_0007865
DiseaseMalignant neoplasm of breast

KRT5 ERBB4 CENPF DYNC2H1 ITGA9 CLIP1 EMSY OTOGL ZNF277 ARFGAP3 MROH7 MACF1 GOLGB1 GABRA4

2.06e-04107412614C0006142
Diseaseasthma, allergic disease

RANBP6 TLR6 EMSY TSLP

3.72e-04791264MONDO_0004979, MONDO_0005271
DiseaseNonsyndromic Deafness

BDP1 MET OTOGL MYO15A

4.09e-04811264C3711374
DiseaseGlucocorticoid use measurement

RANBP6 EMSY TSLP

6.21e-04391263EFO_0009942
DiseaseHEPATOCELLULAR CARCINOMA

MET IGF2R

6.39e-0491262114550
DiseaseHepatocellular carcinoma

MET IGF2R

6.39e-0491262cv:C2239176
DiseaseAutosomal Recessive Polycystic Kidney Disease

DZIP1L PKHD1

6.39e-0491262C0085548
DiseaseProstatic Neoplasms

PDE4D ABR CENPF TLR6 CREB3L4 PPL MET IGF2R POLK

1.35e-036161269C0033578
DiseaseMalignant neoplasm of prostate

PDE4D ABR CENPF TLR6 CREB3L4 PPL MET IGF2R POLK

1.35e-036161269C0376358
DiseaseBardet-Biedl Syndrome

SDCCAG8 CEP290

1.37e-03131262C0752166
DiseaseTremor, Rubral

CP GABRA4

2.09e-03161262C0750940
DiseaseAtaxia, Appendicular

CP GABRA4

2.09e-03161262C0750937
DiseaseAtaxia, Motor

CP GABRA4

2.09e-03161262C0278161
DiseaseLeber congenital amaurosis

SPATA7 CEP290

2.09e-03161262cv:C0339527
DiseaseAtaxia, Sensory

CP GABRA4

2.09e-03161262C0240991
DiseaseAbnormal coordination

CP GABRA4

2.09e-03161262C0520966
Diseaseautosomal recessive polycystic kidney disease (implicated_via_orthology)

DZIP1L PKHD1

2.09e-03161262DOID:0110861 (implicated_via_orthology)
DiseaseAtaxia, Truncal

CP GABRA4

2.09e-03161262C0427190
DiseaseDisorder of eye

SPATA7 SDCCAG8 CEP290 DHDDS IQCB1

2.21e-032121265C0015397
DiseaseAntihistamine use measurement

RANBP6 EMSY

2.36e-03171262EFO_0009943
Diseaserhinitis

RANBP6 EMSY

2.36e-03171262EFO_0008521
DiseaseTourette syndrome, schizophrenia

DNAH10 PHF3

2.65e-03181262EFO_0004895, MONDO_0005090
DiseaseBardet-Biedl syndrome

SDCCAG8 CEP290

2.65e-03181262cv:C0752166
Diseasebody mass index, high density lipoprotein cholesterol measurement

DNAH10 CLIP1

2.95e-03191262EFO_0004340, EFO_0004612
Diseaseasthma, age at onset

RANBP6 EMSY TSLP

3.38e-03701263EFO_0004847, MONDO_0004979
Diseaseceramide measurement

PDE4D CREB3L4 MDN1 ARFGAP3 ADGRA3

3.44e-032351265EFO_0010222
Diseasebasophil count, eosinophil count

RANBP6 EMSY ANAPC1 FNIP1 TSLP

3.82e-032411265EFO_0004842, EFO_0005090
DiseaseHepatitis, Chronic

CP MET

3.95e-03221262C0019189
DiseaseChronic active hepatitis

CP MET

3.95e-03221262C0520463
DiseaseChronic Persistent Hepatitis

CP MET

3.95e-03221262C0149519
DiseaseCryptogenic Chronic Hepatitis

CP MET

3.95e-03221262C0524611
DiseaseAmphetamine-Related Disorders

FKBP15 PDE4D MYO5B

4.10e-03751263C0236733
DiseaseAmphetamine Abuse

FKBP15 PDE4D MYO5B

4.10e-03751263C0236807
DiseaseAmphetamine Addiction

FKBP15 PDE4D MYO5B

4.10e-03751263C0236804

Protein segments in the cluster

PeptideGeneStartEntry
ETAEKCSQSNNQFQK

ABR

196

Q12979
SNIDKFINCTKINGN

ERBB4

351

Q15303
LNECLSVQENNKANK

BDP1

786

A6H8Y1
KLANTCFNEIEKQAQ

ARFGAP3

236

Q9NP61
FELVGQKAITCQKNN

CSMD2

551

Q7Z408
KFSDCTRAAEQLKNN

CEP19

41

Q96LK0
LTVESFSNKIQNKCS

BRDT

871

Q58F21
FSNKIQNKCSGEEQK

BRDT

876

Q58F21
CQYSQALKKVFAQNE

AGR3

71

Q8TD06
GNLDKQLSFKCNVSN

ADGRA3

581

Q8IWK6
KVTSQNKSFICGQNE

AFF2

536

P51816
ANKRCKSLQNSNSEQ

ANKRD62

261

A6NC57
NRFKKQNSSIEEACQ

AOPEP

51

Q8N6M6
LQCGTVSSQKQQALK

ANKRD36B

386

Q8N2N9
QVKIKCQVAKSNSQT

CCDC180

1126

Q9P1Z9
SLQQLQNKIKTCQES

CCDC180

1146

Q9P1Z9
TNTELQIAQTQKKCN

IQCG

271

Q9H095
NQQQTVAKICKCLVN

MROH7

1176

Q68CQ1
KTACNVEEAFINTAK

RAB2B

151

Q8WUD1
QLRCVKFQESNDKTQ

ANAPC1

451

Q9H1A4
FFQVQECNKSSSKDN

CP

351

P00450
KFQRSCLHQTVQQFK

DUOX1

1021

Q9NRD9
LSQDQKKAAAQSQCQ

DZIP1L

366

Q8IYY4
QSQEVKENQTVKFRC

MYLK

421

Q15746
KTTICQVFAALANQK

MDN1

1396

Q9NU22
KAANQIRKCQQSTSA

IP6K2

236

Q9UHH9
DNKIQINAKLQECSN

DNAAF2

661

Q9NVR5
NNCQQVTDKAFKEQR

LMOD3

186

Q0VAK6
FQGIAKACEQNLQKT

MYO15A

3171

Q9UKN7
LEINFSTSIKNACQK

IHO1

396

Q8IYA8
STSIKNACQKYQAQS

IHO1

401

Q8IYA8
INNQTSKCIKTVVFA

ARRDC5

211

A6NEK1
DNVKKQCANLQNAIA

KRT5

401

P13647
ADAAKKQCQQLQTAI

KRT79

376

Q5XKE5
NIKKQCQTLQVSVAD

KRT4

371

P19013
TAICNNGTLFQHQKK

ITGB6

391

P18564
TNAACAALDKKQRNF

MYH2

1441

Q9UKX2
KICANSQQYQQAVKD

PPL

786

O60437
ENCDIFQNLTKKQRQ

PDE4D

546

Q08499
KNQNASLYKDCVFNT

FAM209B

101

Q5JX69
NSVKNKFSDVQVLCS

EVPL

611

Q92817
VEFNKQVCIAKCNST

FKBP15

161

Q5T1M5
KETLNSQFVENCKGV

MUL1

76

Q969V5
AKCQNSKLEAAVAQS

KRT87P

171

A6NCN2
QNQKEEKLCTENFTR

GABRA4

36

P48169
KDCLENQQKLFSAVQ

POC1B

461

Q8TC44
NNCQAAKQFGVLEKN

POGK

216

Q9P215
QLNECKQLSESQVKS

PPP2CA

16

P67775
IERNQTKLDQCQKFS

MACF1

1326

Q9UPN3
TKLDQCQKFSQQYST

MACF1

1331

Q9UPN3
SKQANEGKVNNLSLC

MACF1

3071

Q9UPN3
QKIAQKNQTVFERNC

ITGA9

606

Q13797
ANETFVAKDNKILCN

FHL1

76

Q13642
QQVANIAQKFCKQAI

DYNC2H1

601

Q8NCM8
ENCAQNQKLSNKTIE

ATMIN

231

O43313
QGNSVNLKNSKQACL

DACT1

386

Q9NYF0
KKEENTLVQNYAAQC

BTAF1

886

O14981
QEACKAKEQNLSSQV

CENPF

2461

P49454
QSQKESQCLKSELQA

CEP290

1696

O15078
SQCLKSELQAQKEAN

CEP290

1701

O15078
IKAQECFQKALSLNQ

CFAP70

686

Q5T0N1
KILCTKNNKQNNEFC

FNIP1

871

Q8TF40
CIFNNKTNSKDEQIT

GIMAP8

166

Q8ND71
NQELKDSCISLQKQN

CALCOCO2

156

Q13137
QLQTCFINAAKAEEK

IQCB1

121

Q15051
QSSAEAKFVKQLDQC

HDDC2

131

Q7Z4H3
QTQLQVKTLQCFQTK

EMSY

961

Q7Z589
CFQTKQKQTIHLQAD

EMSY

971

Q7Z589
AQKKRVESIQCFQNT

HLTF

886

Q14527
KIVKEFNSTQDVNIC

ERCC6L2

576

Q5T890
AQAVQATKNYNKCFL

DHDDS

136

Q86SQ9
QNVSEGLEKCQKSLN

DNAH10

1541

Q8IVF4
CQKKFTNAVTLQQHV

SALL2

696

Q9Y467
ACSAQNQELQKKVQE

CREB3L4

251

Q8TEY5
KCNEQTKVIDNFTSQ

CLIP1

751

P30622
QKSCVNVTTKNAAFA

LRRN1

606

Q6UXK5
SDISVIAQNKKCFDN

OTOGL

981

Q3ZCN5
IAQNKKCFDNDIVCS

OTOGL

986

Q3ZCN5
QTQCKENQNSEGKCK

HOXA2

201

O43364
ICKAVNKTTNSKVAQ

HMGCLL1

351

Q8TB92
NDFFNKIVNKNNVRC

MET

371

P08581
IQFCNKKQAAVCQVK

IGF2R

371

P11717
KFCTSNQEAIEKALN

REXO1

831

Q8N1G1
LKETDQSCFVQTAKQ

TRIM36

356

Q9NQ86
SQQKAARAQSKGCFQ

ACAA1

206

P09110
VCAQSNKGFVVINQK

CCT6B

281

Q92526
QQSFSKEAKAQALQA

SDCCAG8

546

Q86SQ7
NDFIQKIANNSYACK

SGK1

36

O00141
VKEDKRCFTANQNNV

SETX

991

Q7Z333
NQQCFKFLQSKAETA

POLR3F

181

Q9H1D9
VNKTSCKVIFSNQTN

PKHD1

966

P08F94
QQESKTNTICKKCAQ

FAM76A

46

Q8TAV0
TNTICKKCAQNVQLY

FAM76A

51

Q8TAV0
KTECIQKGKNNQTEC

SEMA4C

96

Q9C0C4
QKGKNNQTECFNFIR

SEMA4C

101

Q9C0C4
ANSKTKKNVIATENC

RANBP6

966

O60518
DVQNVCFQEKVTCKN

RNASE1

81

P07998
SLVTCNVQQKYNQEK

TET1

1106

Q8NFU7
SSKCVNLAKENQVFQ

ANKRD20A12P

161

Q8NF67
QFETAQKKCQEAINA

ADAM17

526

P78536
NKVIQCFAETGQVQK

CLTC

486

Q00610
KKLTCQVATLNNNAS

CLEC10A

161

Q8IUN9
CAAQNASLLKINNKN

CLEC12A

161

Q5QGZ9
FKKALQENDNVCAQL

CNOT10

316

Q9H9A5
LSNSVQNALACKSKQ

C11orf96

46

Q7Z7L8
ECSTQQTQQKKYLEQ

XIRP2

2506

A4UGR9
NKSGQSICQKLVSAQ

ZNF667

101

Q5HYK9
QCQINQVKFKFQSSN

PLA1A

391

Q53H76
QAQQIKCFNSKLFLC

RNF14

206

Q9UBS8
LCAKTKFNVATQNVS

SENP5

76

Q96HI0
HQSQKQFQCELCVKS

ZBTB11

701

O95625
KTFCQKSQLTQHQRI

ZNF33B

616

Q06732
NQCLKITTSKIFQCN

ZNF138

71

P52744
KNNKNEFVSLINCSS

STAU1

511

O95793
GINKCLSNTQSKIFQ

ZNF721

56

Q8TF20
CNARVKVFSKFANSN

ZNF721

71

Q8TF20
DTFKCEAVNKQSFQT

POLK

581

Q9UBT6
QTKLITAANFCQNGK

WDR44

691

Q5JSH3
NNCGKSFISKSQLQV

ZNF585B

301

Q52M93
KNSCVQQSDNLKVAQ

PHF3

1706

Q92576
NTENCVEFQKLNVSN

SLC6A11

176

P48066
NIKQASNCVTYDAKE

SPATA7

301

Q9P0W8
KVTTNKCLEQVSQLQ

TSLP

131

Q969D9
SQNTNKTCEECLKNV

PTTG1IP

41

P53801
TNIKLNDDNCQVFIK

TLR6

226

Q9Y2C9
KLNQCLTTAQSKVFQ

ZNF91

141

Q05481
NIVNCNEFLCTLQKK

ZNF277

206

Q9NRM2
KDSAQNCTRAINNKQ

ZCRB1

61

Q8TBF4
KCNECGKVFNQQATL

ZNF860

511

A6NHJ4
SKCEIQRNSFKQNSN

ZNF354B

186

Q96LW1
CEQHGKNIVQNSFSK

ZNF224

626

Q9NZL3
KQFCVSNINQKVKFQ

FARS2

341

O95363
NECEKAFNAKSQLVI

ZFP37

576

Q9Y6Q3
VTCVDQDFKSQKNFI

TM2D3

106

Q9BRN9
TQQEIKLCQKSNDIS

WDR41

271

Q9HAD4
NECEKAFQTKAILVQ

ZNF501

81

Q96CX3
KQCLSNTQNKIFQTH

ZNF722

146

A0A1W2PQL4
VCDKCQKAFSQNISL

ZFP69

356

Q49AA0
ALEEITKQQTKQNCT

ZRANB3

816

Q5FWF4
SKAQTEVQLQQKVCD

GOLGB1

2266

Q14789
ACTCQNNINKVDSKI

PRKCH

221

P24723
AQLANEKQKCIDSAN

LRRCC1

976

Q9C099
NQILCQSKDEFAQNS

MYO5B

1036

Q9ULV0
SVDCSLKAQQQAKAV

EXD3

696

Q8N9H8