Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	Golgi localization	GOLGA8O ARCN1 GOLGA8N	3.12e-05	27	47	3	GO:0051645
GeneOntologyBiologicalProcess	Golgi organization	GOLGA8R COG2 GOLGA8O GOLGA8Q GOLGA8N	3.93e-05	168	47	5	GO:0007030
GeneOntologyCellularComponent	Golgi cis cisterna	GOLGA8R GOLGA8O GOLGA8Q GOLGA8N	9.53e-07	33	48	4	GO:0000137
GeneOntologyCellularComponent	cis-Golgi network	GOLGA8R GOLGA8O GOLGA8Q GOLGA8N	4.32e-05	85	48	4	GO:0005801
GeneOntologyCellularComponent	Golgi stack	GOLGA8R COG2 GOLGA8O GOLGA8Q GOLGA8N	4.45e-05	171	48	5	GO:0005795
GeneOntologyCellularComponent	Golgi cisterna membrane	GOLGA8R GOLGA8O GOLGA8Q GOLGA8N	6.41e-05	94	48	4	GO:0032580
GeneOntologyCellularComponent	Golgi membrane	COG2 C1GALT1C1 MAN1A2 PGAP3 GOLGA8O ARCN1 DOP1A GOLGA8N	2.14e-04	721	48	8	GO:0000139
GeneOntologyCellularComponent	Golgi cisterna	GOLGA8R GOLGA8O GOLGA8Q GOLGA8N	2.60e-04	135	48	4	GO:0031985
GeneOntologyCellularComponent	Golgi apparatus subcompartment	GOLGA8R COG2 GOLGA8O GOLGA8Q DOP1A GOLGA8N	5.06e-04	443	48	6	GO:0098791
MousePheno	abnormal Golgi vesicle transport	GOLGA8O ARCN1 GOLGA8N	2.75e-05	22	38	3	MP:0030949
Domain	GOLGA2L5	GOLGA8R GOLGA8O GOLGA8N	1.19e-05	18	47	3	PF15070
Domain	Golgin_A	GOLGA8R GOLGA8O GOLGA8N	1.19e-05	18	47	3	IPR024858
Domain	ARM-type_fold	FMNL3 TSC2 UPF2 PIK3C2B HECTD1	1.57e-03	339	47	5	IPR016024
Pathway	WP_15Q133_COPY_NUMBER_VARIATION_SYNDROME	GOLGA8R GOLGA8O GOLGA8Q	2.84e-05	23	37	3	M39883
Pathway	REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION	COG2 MAN1A2 GOLGA8O ARCN1 GOLGA8N	1.73e-04	202	37	5	MM15650
Pathway	REACTOME_COPI_MEDIATED_ANTEROGRADE_TRANSPORT	COG2 GOLGA8O ARCN1 GOLGA8N	1.90e-04	110	37	4	MM15350
Pubmed	The antiinflammatory endothelial tyrosine kinase Tie2 interacts with a novel nuclear factor-kappaB inhibitor ABIN-2.	TEK TNIP2	1.87e-06	2	48	2	12609966
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	ZFYVE28 TRA2A TSC2 MCMBP PGAP3 LMNB1 LONRF2 ARCN1	6.92e-06	736	48	8	29676528
Pubmed	Ttyh1, a Ca(2+)-binding protein localized to the endoplasmic reticulum, is required for early embryonic development.	ILDR2 GOLGA8O GOLGA8N	8.79e-06	29	48	3	20568244
Pubmed	ARD1 stabilization of TSC2 suppresses tumorigenesis through the mTOR signaling pathway.	TSC2 NAA20	1.12e-05	4	48	2	20145209
Pubmed	Angulin proteins ILDR1 and ILDR2 regulate alternative pre-mRNA splicing through binding to splicing factors TRA2A, TRA2B, or SRSF1.	ILDR2 TRA2A	1.86e-05	5	48	2	28785060
Pubmed	Angiopoietin-1/Tie2 signaling pathway inhibits lipopolysaccharide-induced activation of RAW264.7 macrophage cells.	TEK TNIP2	2.79e-05	6	48	2	20060382
Pubmed	Control of HIF-1{alpha} and vascular signaling in fetal lung involves cross talk between mTORC1 and the FGF-10/FGFR2b/Spry2 airway branching periodicity clock.	TSC2 TEK	3.90e-05	7	48	2	20622121
Pubmed	High-throughput analyses of hnRNP H1 dissects its multi-functional aspect.	HKDC1 TRA2A KIF9 MAN1A2 LMNB1 PIK3C2B TNIP2 SYNGAP1	7.14e-05	1021	48	8	26760575
Pubmed	GM130 regulates pulmonary surfactant protein secretion in alveolar type II cells.	GOLGA8O GOLGA8N	1.44e-04	13	48	2	33740186
Pubmed	Loss of GM130 does not impair oocyte meiosis and embryo development in mice.	GOLGA8O GOLGA8N	1.44e-04	13	48	2	32873390
Pubmed	GM130, a cis-Golgi protein, regulates meiotic spindle assembly and asymmetric division in mouse oocyte.	GOLGA8O GOLGA8N	1.44e-04	13	48	2	21552007
Pubmed	IGF signaling directs ventricular cardiomyocyte proliferation during embryonic heart development.	TEK KRT18	1.44e-04	13	48	2	21429986
Pubmed	GOLGA2 loss causes fibrosis with autophagy in the mouse lung and liver.	GOLGA8O GOLGA8N	1.44e-04	13	48	2	29128360
Pubmed	Globozoospermia and lack of acrosome formation in GM130-deficient mice.	GOLGA8O GOLGA8N	1.44e-04	13	48	2	28055014
Pubmed	Loss of the golgin GM130 causes Golgi disruption, Purkinje neuron loss, and ataxia in mice.	GOLGA8O GOLGA8N	1.44e-04	13	48	2	28028212
Pubmed	GM130 and p115 play a key role in the organisation of the early secretory pathway during skeletal muscle differentiation.	GOLGA8O GOLGA8N	1.68e-04	14	48	2	30630895
Pubmed	Golgb1 regulates protein glycosylation and is crucial for mammalian palate development.	GOLGA8O GOLGA8N	1.68e-04	14	48	2	27226319
Pubmed	Cdk1 protects against oxygen-glucose deprivation and reperfusion-induced Golgi fragmentation and apoptosis through mediating GM130 phosphorylation.	GOLGA8O GOLGA8N	1.68e-04	14	48	2	37831422
Pubmed	Oligoasthenoteratospermia and sperm tail bending in PPP4C-deficient mice.	GOLGA8O GOLGA8N	1.68e-04	14	48	2	33543287
Pubmed	The a3 isoform of V-ATPase regulates insulin secretion from pancreatic beta-cells.	GOLGA8O GOLGA8N	1.94e-04	15	48	2	17046993
Pubmed	GM130 Regulates Golgi-Derived Spindle Assembly by Activating TPX2 and Capturing Microtubules.	GOLGA8O GOLGA8N	1.94e-04	15	48	2	26165940
Pubmed	Mouse oocytes within germ cell cysts and primordial follicles contain a Balbiani body.	GOLGA8O GOLGA8N	1.94e-04	15	48	2	17189423
Pubmed	Calumin, a novel Ca2+-binding transmembrane protein on the endoplasmic reticulum.	GOLGA8O GOLGA8N	1.94e-04	15	48	2	17204322
Pubmed	RhoA-mediated FMNL1 regulates GM130 for actin assembly and phosphorylates MAPK for spindle formation in mouse oocyte meiosis.	GOLGA8O GOLGA8N	1.94e-04	15	48	2	26083584
Pubmed	Demonstration of the expression and the enzymatic activity of N-acetylglucosaminyltransferase IX in the mouse brain.	GOLGA8O GOLGA8N	1.94e-04	15	48	2	16413118
Pubmed	WDR38, a novel equatorial segment protein, interacts with the GTPase protein RAB19 and Golgi protein GM130 to play roles in acrosome biogenesis.	GOLGA8O GOLGA8N	1.94e-04	15	48	2	37635409
Pubmed	Golgi disruption and early embryonic lethality in mice lacking USO1.	GOLGA8O GOLGA8N	1.94e-04	15	48	2	23185636
Pubmed	Golga5 is dispensable for mouse embryonic development and postnatal survival.	GOLGA8O GOLGA8N	1.94e-04	15	48	2	28509431
Pubmed	LIM kinase 2 is widely expressed in all tissues.	GOLGA8O GOLGA8N	2.21e-04	16	48	2	16399995
Pubmed	Screening for replication of genome-wide SNP associations in sporadic ALS.	MAN1A2 UPF2	2.21e-04	16	48	2	18987618
Pubmed	Molecular characterization of mitocalcin, a novel mitochondrial Ca2+-binding protein with EF-hand and coiled-coil domains.	GOLGA8O GOLGA8N	2.21e-04	16	48	2	16336229
Pubmed	SLC24A5 encodes a trans-Golgi network protein with potassium-dependent sodium-calcium exchange activity that regulates human epidermal melanogenesis.	GOLGA8O GOLGA8N	2.21e-04	16	48	2	18166528
Pubmed	Molecular motor KIF1C is not essential for mouse survival and motor-dependent retrograde Golgi apparatus-to-endoplasmic reticulum transport.	GOLGA8O GOLGA8N	2.21e-04	16	48	2	11784862
Pubmed	p125/Sec23-interacting protein (Sec23ip) is required for spermiogenesis.	GOLGA8O GOLGA8N	2.21e-04	16	48	2	21640725
Pubmed	Phospholipase D2 localizes to the plasma membrane and regulates angiotensin II receptor endocytosis.	GOLGA8O GOLGA8N	2.50e-04	17	48	2	14718562
Pubmed	The Protein Tyrosine Phosphatase MEG2 Regulates the Transport and Signal Transduction of Tropomyosin Receptor Kinase A.	GOLGA8O GOLGA8N	2.50e-04	17	48	2	27655914
Pubmed	Vesicle budding from endoplasmic reticulum is involved in calsequestrin routing to sarcoplasmic reticulum of skeletal muscles.	GOLGA8O GOLGA8N	2.50e-04	17	48	2	14728599
Pubmed	Dynamics and function of CXCR4 in formation of the granule cell layer during hippocampal development.	GOLGA8O GOLGA8N	2.50e-04	17	48	2	28717168
Pubmed	A truncating mutation of TRAPPC9 is associated with autosomal-recessive intellectual disability and postnatal microcephaly.	GOLGA8O GOLGA8N	2.50e-04	17	48	2	20004763
Pubmed	GREB1: An evolutionarily conserved protein with a glycosyltransferase domain links ERα glycosylation and stability to cancer.	TRA2A LMNB1 UPF2 ARCN1	2.57e-04	223	48	4	33731348
Pubmed	Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).	C1GALT1C1 MAN1A2 KRT18 ADAMTS3 RAB22A	2.71e-04	417	48	5	19199708
Pubmed	Notch inhibition by the ligand DELTA-LIKE 3 defines the mechanism of abnormal vertebral segmentation in spondylocostal dysostosis.	GOLGA8O GOLGA8N	2.81e-04	18	48	2	21147753
Pubmed	p115 Interacts with the GLUT4 vesicle protein, IRAP, and plays a critical role in insulin-stimulated GLUT4 translocation.	GOLGA8O GOLGA8N	2.81e-04	18	48	2	15800058
Pubmed	N-cadherin sustains motility and polarity of future cortical interneurons during tangential migration.	GOLGA8O GOLGA8N	2.81e-04	18	48	2	24227724
Pubmed	Altered GLUT4 trafficking in adipocytes in the absence of the GTPase Arfrp1.	GOLGA8O GOLGA8N	2.81e-04	18	48	2	20230794
Pubmed	Flightless, secreted through a late endosome/lysosome pathway, binds LPS and dampens cytokine secretion.	GOLGA8O GOLGA8N	2.81e-04	18	48	2	22718342
Pubmed	Protein kinase LKB1 regulates polarized dendrite formation of adult hippocampal newborn neurons.	GOLGA8O GOLGA8N	2.81e-04	18	48	2	24367100
Pubmed	Expression, localization, and biochemical characterization of nicotinamide mononucleotide adenylyltransferase 2.	GOLGA8O GOLGA8N	2.81e-04	18	48	2	20943658
Pubmed	Yip1B isoform is localized at ER-Golgi intermediate and cis-Golgi compartments and is not required for maintenance of the Golgi structure in skeletal muscle.	GOLGA8O GOLGA8N	2.81e-04	18	48	2	25208654
Pubmed	C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.	TMEM209 TRA2A TSC2 MCMBP LMNB1 HECTD1 POLD2 ARCN1	2.97e-04	1257	48	8	37317656
Pubmed	SDF2L1 interacts with the ER-associated degradation machinery and retards the degradation of mutant proinsulin in pancreatic β-cells.	GOLGA8O GOLGA8N	3.14e-04	19	48	2	23444373
Pubmed	Presenilin 1 and presenilin 2 have differential effects on the stability and maturation of nicastrin in Mammalian brain.	GOLGA8O GOLGA8N	3.14e-04	19	48	2	12646573
Pubmed	Stage-dependent function of Wnt5a during male external genitalia development.	GOLGA8O GOLGA8N	3.14e-04	19	48	2	34255394
Pubmed	Presenilin 1 mediates the turnover of telencephalin in hippocampal neurons via an autophagic degradative pathway.	GOLGA8O GOLGA8N	3.14e-04	19	48	2	15452145
Pubmed	Scrg1, a novel protein of the CNS is targeted to the large dense-core vesicles in neuronal cells.	GOLGA8O GOLGA8N	3.14e-04	19	48	2	14622145
Pubmed	CLASP2 safeguards hematopoietic stem cell properties during mouse and fish development.	GOLGA8O GOLGA8N	3.14e-04	19	48	2	35705037
Pubmed	Divergent functions and distinct localization of the Notch ligands DLL1 and DLL3 in vivo.	GOLGA8O GOLGA8N	3.14e-04	19	48	2	17664336
Pubmed	Deletion of IFT20 exclusively in the RPE ablates primary cilia and leads to retinal degeneration.	GOLGA8O GOLGA8N	3.14e-04	19	48	2	38048369
Pubmed	Spatial regulation of Raf kinase signaling by RKTG.	GOLGA8O GOLGA8N	3.14e-04	19	48	2	17724343
Pubmed	Pilt is a coiled-coil domain-containing protein that localizes at the trans-Golgi complex and regulates its structure.	GOLGA8O GOLGA8N	3.14e-04	19	48	2	22841714
Pubmed	Regulation of amino acid transporter ATA2 by ubiquitin ligase Nedd4-2.	GOLGA8O GOLGA8N	3.14e-04	19	48	2	17003038
Pubmed	Cell influx and contractile actomyosin force drive mammary bud growth and invagination.	GOLGA8O GOLGA8N	3.14e-04	19	48	2	34042944
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	HEXB COG2 TSC2 MAN1A2 ANK2 HECTD1 ARCN1 SYNGAP1	3.44e-04	1285	48	8	35914814
Pubmed	The COPI vesicle complex binds and moves with survival motor neuron within axons.	GOLGA8O GOLGA8N	3.49e-04	20	48	2	21300694
Pubmed	Intraflagellar transport molecules in ciliary and nonciliary cells of the retina.	GOLGA8O GOLGA8N	3.49e-04	20	48	2	20368623
Pubmed	Furin is the primary in vivo convertase of angiopoietin-like 3 and endothelial lipase in hepatocytes.	GOLGA8O GOLGA8N	3.49e-04	20	48	2	23918928
Pubmed	Maximizing the ovarian reserve in mice by evading LINE-1 genotoxicity.	GOLGA8O GOLGA8N	3.49e-04	20	48	2	31949138
Pubmed	Development of the post-natal growth plate requires intraflagellar transport proteins.	GOLGA8O GOLGA8N	3.49e-04	20	48	2	17359961
Pubmed	The molecular complex of ciliary and golgin protein is crucial for skull development.	GOLGA8O GOLGA8N	3.49e-04	20	48	2	34128978
Pubmed	TMED2/emp24 is required in both the chorion and the allantois for placental labyrinth layer development.	GOLGA8O GOLGA8N	3.49e-04	20	48	2	30236446
Pubmed	Overlapping Role of SCYL1 and SCYL3 in Maintaining Motor Neuron Viability.	GOLGA8O GOLGA8N	3.49e-04	20	48	2	29437892
Pubmed	Rap2 function requires palmitoylation and recycling endosome localization.	GOLGA8O GOLGA8N	3.85e-04	21	48	2	19061864
Pubmed	Over-expression of Rififylin, a new RING finger and FYVE-like domain-containing protein, inhibits recycling from the endocytic recycling compartment.	GOLGA8O GOLGA8N	3.85e-04	21	48	2	15229288
Pubmed	Canonical and noncanonical intraflagellar transport regulates craniofacial skeletal development.	GOLGA8O GOLGA8N	3.85e-04	21	48	2	27118846
Pubmed	Ror2 enhances polarity and directional migration of primordial germ cells.	GOLGA8O GOLGA8N	3.85e-04	21	48	2	22216013
Pubmed	Mechanism of primitive duct formation in the pancreas and submandibular glands: a role for SDF-1.	GOLGA8O GOLGA8N	3.85e-04	21	48	2	20003423
Pubmed	Dynamics of the rhomboid-like protein RHBDD2 expression in mouse retina and involvement of its human ortholog in retinitis pigmentosa.	GOLGA8O GOLGA8N	3.85e-04	21	48	2	23386608
Pubmed	DJ-1 associates with synaptic membranes.	GOLGA8O GOLGA8N	3.85e-04	21	48	2	21645620
Pubmed	Single Cell Sequencing Reveals Mechanisms of Persistent Truncus Arteriosus Formation after PDGFRα and PDGFRβ Double Knockout in Cardiac Neural Crest Cells.	GOLGA8O GOLGA8N	3.85e-04	21	48	2	36292593
Pubmed	ATG5 is required for B cell polarization and presentation of particulate antigens.	TRA2A SYF2 LMNB1 GOLGA8O POLD2 GOLGA8N	3.92e-04	701	48	6	30196744
Pubmed	Control of craniofacial development by the collagen receptor, discoidin domain receptor 2.	GOLGA8O GOLGA8N	4.23e-04	22	48	2	36656123
Pubmed	Comparative analysis of vertebrates reveals that mouse primordial oocytes do not contain a Balbiani body.	GOLGA8O GOLGA8N	4.23e-04	22	48	2	34897463
Pubmed	Common and distinctive localization patterns of Crumbs polarity complex proteins in the mammalian eye.	GOLGA8O GOLGA8N	4.63e-04	23	48	2	25636444
Pubmed	ADP Ribosylation Factor 4 (Arf4) Regulates Radial Migration through N-Cadherin Trafficking during Cerebral Cortical Development.	GOLGA8O GOLGA8N	4.63e-04	23	48	2	37848288
Pubmed	ADP-ribosylation factor-like GTPase ARFRP1 is required for trans-Golgi to plasma membrane trafficking of E-cadherin.	GOLGA8O GOLGA8N	4.63e-04	23	48	2	18662990
Pubmed	Reelin and stk25 have opposing roles in neuronal polarization and dendritic Golgi deployment.	GOLGA8O GOLGA8N	4.63e-04	23	48	2	21111240
Pubmed	Mapping of Cbln1-like immunoreactivity in adult and developing mouse brain and its localization to the endolysosomal compartment of neurons.	GOLGA8O GOLGA8N	4.63e-04	23	48	2	18001291
Pubmed	Pofut1 is required for the proper localization of the Notch receptor during mouse development.	GOLGA8O GOLGA8N	4.63e-04	23	48	2	18547789
Pubmed	Myocardial Angiopoietin-1 Controls Atrial Chamber Morphogenesis by Spatiotemporal Degradation of Cardiac Jelly.	TEK ADAMTS3	5.05e-04	24	48	2	29791855
Pubmed	Regulation of cell polarity in the cartilage growth plate and perichondrium of metacarpal elements by HOXD13 and WNT5A.	GOLGA8O GOLGA8N	5.05e-04	24	48	2	24161848
Pubmed	Mesenchymal Wnts are required for morphogenetic movements of calvarial osteoblasts during apical expansion.	GOLGA8O GOLGA8N	5.05e-04	24	48	2	38814743
Pubmed	The PCP genes Celsr1 and Vangl2 are required for normal lung branching morphogenesis.	GOLGA8O GOLGA8N	5.05e-04	24	48	2	20223754
Pubmed	Ectopic clustering of Cajal-Retzius and subplate cells is an initial pathological feature in Pomgnt2-knockout mice, a model of dystroglycanopathy.	GOLGA8O GOLGA8N	5.05e-04	24	48	2	26060116
Pubmed	Dual role for CXCL12 signaling in semilunar valve development.	GOLGA8O GOLGA8N	5.05e-04	24	48	2	34433040
Pubmed	Essential role of cyclin-G-associated kinase (Auxilin-2) in developing and mature mice.	GOLGA8O GOLGA8N	5.05e-04	24	48	2	18434600
Pubmed	Sorting receptor Rer1 controls surface expression of muscle acetylcholine receptors by ER retention of unassembled alpha-subunits.	GOLGA8O GOLGA8N	5.05e-04	24	48	2	21187406
Pubmed	Stalk cell phenotype depends on integration of Notch and Smad1/5 signaling cascades.	GOLGA8O GOLGA8N	5.05e-04	24	48	2	22364862
Pubmed	Lifeguard Inhibits Fas Ligand-mediated Endoplasmic Reticulum-Calcium Release Mandatory for Apoptosis in Type II Apoptotic Cells.	GOLGA8O GOLGA8N	5.48e-04	25	48	2	26582200
Pubmed	Nubp1 is required for lung branching morphogenesis and distal progenitor cell survival in mice.	GOLGA8O GOLGA8N	5.48e-04	25	48	2	23028652
Pubmed	A Golgi Lipid Signaling Pathway Controls Apical Golgi Distribution and Cell Polarity during Neurogenesis.	GOLGA8O GOLGA8N	5.48e-04	25	48	2	29587143
Cytoband	Ensembl 112 genes in cytogenetic band chr15q13	GOLGA8R GOLGA8O GOLGA8Q GOLGA8N	3.83e-06	100	48	4	chr15q13
Cytoband	15q13.2	GOLGA8Q GOLGA8N	2.22e-04	21	48	2	15q13.2
Coexpression	HALLMARK_PROTEIN_SECRETION	COG2 KRT18 ARCN1 DOP1A RAB22A	8.97e-07	96	48	5	M5910
ToppCell	COVID_non-vent-Lymphocytic-ILC\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	GOLGA8R GOLGA8O GOLGA8Q TBX21 GOLGA8N	2.36e-06	199	48	5	df4f7d5be099e3e6054f3b812ccf70251664e4c0
ToppCell	COVID_vent-Lymphocytic-ILC\|COVID_vent / Disease condition, Lineage, Cell class and subclass	GOLGA8R GOLGA8O GOLGA8Q TBX21 GOLGA8N	2.36e-06	199	48	5	e3ff7fa1b1de1aaf6b46cdf49afa95bad457728a
ToppCell	COVID_vent-Lymphocytic-ILC-NK_cell\|COVID_vent / Disease condition, Lineage, Cell class and subclass	GOLGA8R GOLGA8O GOLGA8Q TBX21 GOLGA8N	2.36e-06	199	48	5	5f914962e2572b0c6372465b81b7496fa663d93c
ToppCell	COVID_non-vent-Lymphocytic-ILC-NK_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	GOLGA8R GOLGA8O GOLGA8Q TBX21 GOLGA8N	2.36e-06	199	48	5	ed35d747f11f6ea6a5cb7061057f0a98d9e0db99
ToppCell	10x5'-GI_large-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_large-bowel / Manually curated celltypes from each tissue	GOLGA8O PLEKHG4 DOP1A SYNGAP1	2.17e-05	152	48	4	95944864ce7539ff8de028f5700694931338f3ff
ToppCell	ICU-SEP-Lymphocyte-T_NK-NK_CD56bright\|ICU-SEP / Disease, Lineage and Cell Type	GOLGA8R ZNF285 GOLGA8Q TBX21	2.53e-05	158	48	4	53a942cdab4a3c6813dbe11368135a24b8de1880
ToppCell	Cerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	ZFYVE28 PRMT8 ADAMTS3 TRPM2	3.14e-05	167	48	4	9efb9511a211d0824bb97f82c1a5860c43d2138f
ToppCell	Cerebellum-Neuronal-Inhibitory\|Cerebellum / BrainAtlas - Mouse McCarroll V32	ZFYVE28 PRMT8 ADAMTS3 TRPM2	3.14e-05	167	48	4	904c613aac3f9919a432b110bb1dcc832b5aec0a
ToppCell	PND03-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HEXB ZFYVE28 LMNB1 LONRF2	3.29e-05	169	48	4	a1efc20e34a81ae32f8d278a5486811ade03ef24
ToppCell	IPF-Epithelial-Mesothelial\|IPF / Disease state, Lineage and Cell class	PHYHIP LONRF2 KRT18 ADAMTS3	4.20e-05	180	48	4	1fa54bf4dba72866b2295639d991af639341bc08
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Neuronal-medium_spiny_neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PHYHIP ZFYVE28 PRMT8 ADAMTS3	4.39e-05	182	48	4	d41ff834b8fc1d0e23cac7ae261de5f72874e462
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Neuronal-SPN_Neuron_STR\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PHYHIP ZFYVE28 PRMT8 ADAMTS3	4.39e-05	182	48	4	6cde859edfe7607bd7ada89d20258413d06f4207
ToppCell	5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PHYHIP TCEAL7 ANK2 ADAMTS3	4.67e-05	185	48	4	9faa35ceb89ccd2979072286f063687c9f846ce3
ToppCell	COPD-Epithelial-Mesothelial\|World / Disease state, Lineage and Cell class	PHYHIP LONRF2 KRT18 ADAMTS3	4.67e-05	185	48	4	23579988036fc1925992c31919750f9b3fe9f790
ToppCell	Cerebellum-Neuronal\|Cerebellum / BrainAtlas - Mouse McCarroll V32	ZFYVE28 PRMT8 LONRF2 TRPM2	4.87e-05	187	48	4	61b9d6eb131a674598aa8409d7fa909c8765442d
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)\|Striatum / BrainAtlas - Mouse McCarroll V32	PHYHIP ZFYVE28 TCEAL7 UPF2	4.98e-05	188	48	4	e34ea7014c5a059a7db38f78bd903cf02616ddd3
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Neuronal-SPN_Neuron_STR\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PHYHIP ZFYVE28 PRMT8 ADAMTS3	5.08e-05	189	48	4	851f8144aed5c7f80302911cd6b03f14bde7b56d
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Neuronal-medium_spiny_neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PHYHIP ZFYVE28 PRMT8 ADAMTS3	5.08e-05	189	48	4	3e8e30160a8d6f531ff743cb5918c9e79481f1bd
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PHYHIP ZFYVE28 PRMT8 ADAMTS3	5.18e-05	190	48	4	1c5cf933ce71fed5638b9ef31eb81f6c2b6dadbc
ToppCell	proximal-3-Endothelial-Vein\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	TEK ADAMTS3 PLEKHG4 PIK3C2B	5.73e-05	195	48	4	c81eb541c15b866f9b6ca6a5f1751c5f1243f4fb
ToppCell	proximal-Endothelial-Vein\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	TEK ADAMTS3 PLEKHG4 PIK3C2B	5.73e-05	195	48	4	0aebdd635a956dd2367883c1cf73d73ce9790635
ToppCell	proximal-Endothelial-Vein-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	TEK ADAMTS3 PLEKHG4 PIK3C2B	5.73e-05	195	48	4	df00f94facc5d6107aac83cef3c64fefc7f8e562
ToppCell	Striatum-Neuronal-Excitatory\|Striatum / BrainAtlas - Mouse McCarroll V32	PHYHIP ZFYVE28 TCEAL7 UPF2	5.85e-05	196	48	4	67400193ba469cf4d939e94f5ed94995e384bc07
ToppCell	Sepsis-ICU-SEP-Lymphocyte-T/NK-NK_CD56bright\|ICU-SEP / Disease, condition lineage and cell class	GOLGA8R ZNF285 GOLGA8Q TBX21	5.97e-05	197	48	4	c187e3fc2160b0165eb039cf09a6e621016068b7
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated\|COVID-19_Mild / Disease, condition lineage and cell class	GOLGA8R GOLGA8O GOLGA8Q TBX21	6.33e-05	200	48	4	2281debd86e5d92e8fe0397aec9ef670800f7471
Disease	vitamin D measurement, COVID-19	GLS2 ADAMTS3	2.44e-03	49	44	2	EFO_0004631, MONDO_0100096
Disease	adverse effect, response to xenobiotic stimulus	FMNL3 GLS2	3.52e-03	59	44	2	EFO_0009658, GO_0009410

Protein segments in the cluster

Peptide	Gene	Start	Entry
DYETHKSKRRERMDD	AKAP2	811	Q9Y2D5
EYDEYRALHARMETV	ELL2	551	O00472
AHLLDMVFYSDEKER	DOP1A	2046	Q5JWR5
HEEMLKDEVRTLTYR	PRMT8	86	Q9NR22
SEDERMELSKSFRVY	C1GALT1C1	56	Q96EU7
NHLMETLYSRKSEED	C6orf201	11	Q7Z4U5
REVMERDAKDYADSI	RAB22A	126	Q9UL26
NTYTEKMREALRHFD	ZFYVE28	151	Q9HCC9
AIDMTKRSYADESFH	ANK2	3116	Q01484
ADDFRVKYETELAMR	KRT18	161	P05783
MYEEEINETRRKHET	LMNB1	211	P20700
DIFRYSSMEDHLEIL	POLD2	351	P49005
YEHMESLDLEADRIR	HARBI1	326	Q96MB7
DEDAYDMRKALSRDT	NAA20	146	P61599
HMERSLRYFEEESKD	GOLGA8Q	151	H3BV12
DMEQKDYDSRTALHV	GLS2	511	Q9UI32
ELSDRKRIYDEEMSE	LONRF2	516	Q1L5Z9
TDDFAHEMIRYGDDK	KIF9	16	Q9HAQ2
QMEYDALSRLRHDKE	PIK3C2B	31	O00750
IDMSKDFHYRESDLE	ADAMTS3	211	O15072
MARDLYDDHFKAVES	HECTD1	836	Q9ULT8
HRFEKLMEYFRNEDS	FMNL3	301	Q8IVF7
DHEARKMYDDAIEAI	MAN1A2	416	O60476
HEKYTISMDFVRRLE	COG2	341	Q14746
HMERSLRYFEEESKD	GOLGA8R	151	I6L899
HMERSLRYFEEESKD	GOLGA8O	151	A6NCC3
SKDVRDMDDAYDRLT	HEXB	516	P07686
MEAKYEEILHDSLDR	CCDC153	151	Q494R4
RTFTEMDSHEEKVFR	ARCN1	131	P48444
PSRHKRSYEDDDDMD	MCMBP	161	Q9BTE3
LSEDRHKQYEEFAMS	UPF2	391	Q9HAU5
FHTRDTDLTEKMDYF	PGAP3	156	Q96FM1
METYERLREKHGEEF	SYF2	146	O95926
KVDRFLYHMRLSDDT	HKDC1	21	Q2TB90
DYRTAMDKADELYDR	PLEKHG4	416	Q58EX7
YFSDTFDHLIEMDKR	SBNO2	986	Q9Y2G9
MEDSDLERVTHYFID	PHYHIP	26	Q92561
SEEFDYELAMSTRLH	ABRA	266	Q8N0Z2
DIDYRHFKDEEMTRE	TCEAL7	51	Q9BRU2
YKDDFMSERADRERA	TNIP2	306	Q8NFZ5
SMDESRLDRVKEYEE	SYNGAP1	1186	Q96PV0
MEYNKEDRESFRHSQ	ILDR2	391	Q71H61
SSEEMLALAEEYEHR	TRPM2	671	O94759
YFERIDDSKEAMERA	TRA2A	166	Q13595
RMKEYASKDDHRDFA	TEK	856	Q02763
DKEDYMTDLRTLDTF	TMEM209	231	Q96SK2
MEEKLYRRAQHDDSL	ZNF285	171	Q96NJ3
RDHSYEAEFRAVSMK	TBX21	391	Q9UL17
MAAERFKEHRDTALY	TSC2	1236	P49815
HMERSLRYFEEESKD	GOLGA8N	151	F8WBI6
EEPEMLEEADHRRKY	NLRP13	166	Q86W25