Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ATP hydrolysis activity	VWA8 PEX1 ATP13A5 DDX27 DQX1 HELZ2 NAV3 NAV2 DDX3Y ABCC12 ATP2B1 ATP2B2 DDX11L8 DYNC1H1 MOV10 KIF22	2.25e-06	441	178	16	GO:0016887
GeneOntologyMolecularFunction	ATP-dependent activity	VWA8 PEX1 ATP13A5 DDX27 DQX1 HELZ2 NAV3 NAV2 DDX3Y ABCC12 ATP2B1 ATP2B2 ATP4B DDX11L8 DYNC1H1 MOV10 KIF22	3.70e-05	614	178	17	GO:0140657
GeneOntologyMolecularFunction	guanyl-nucleotide exchange factor activity	DENND2A NET1 PLEKHG7 ARHGEF17 ARHGEF15 ARHGEF10L RAPGEF3 DOCK7 HERC1 DNMBP	4.42e-05	231	178	10	GO:0005085
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	DENND2A ARHGAP40 NET1 ARHGAP10 PLEKHG7 ARHGEF17 ARHGEF15 ARHGEF10L TBC1D4 RAPGEF3 DOCK7 HERC1 DNMBP GPSM1	1.88e-04	507	178	14	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	DENND2A ARHGAP40 NET1 ARHGAP10 PLEKHG7 ARHGEF17 ARHGEF15 ARHGEF10L TBC1D4 RAPGEF3 DOCK7 HERC1 DNMBP GPSM1	1.88e-04	507	178	14	GO:0030695
GeneOntologyMolecularFunction	P-type transmembrane transporter activity	ATP13A5 ATP2B1 ATP2B2 ATP4B	2.88e-04	36	178	4	GO:0140358
GeneOntologyMolecularFunction	P-type ion transporter activity	ATP13A5 ATP2B1 ATP2B2 ATP4B	2.88e-04	36	178	4	GO:0015662
GeneOntologyMolecularFunction	transcription coactivator activity	DTX1 TRIM14 TRRAP KMT2C TRIM28 HELZ2 RBM14 MED12L DOT1L ZBED1	4.04e-04	303	178	10	GO:0003713
GeneOntologyMolecularFunction	transcription coregulator activity	SUPT20H DTX1 TRIM14 TRRAP DHRS7B KMT2C ZBTB32 TRIM28 HELZ2 RBM14 MED12L DOT1L ZBED1 NR0B2	5.31e-04	562	178	14	GO:0003712
GeneOntologyMolecularFunction	helicase activity	DDX27 DQX1 HELZ2 NAV2 DDX3Y DDX11L8 MOV10	5.48e-04	158	178	7	GO:0004386
GeneOntologyMolecularFunction	RNA helicase activity	DDX27 HELZ2 DDX3Y DDX11L8 MOV10	6.64e-04	78	178	5	GO:0003724
GeneOntologyMolecularFunction	ATP-dependent activity, acting on RNA	DDX27 HELZ2 DDX3Y DDX11L8 MOV10	7.45e-04	80	178	5	GO:0008186
GeneOntologyMolecularFunction	tRNA (cytidine-5-)-methyltransferase activity	NSUN2 TRDMT1	7.76e-04	5	178	2	GO:0016428
GeneOntologyBiologicalProcess	N-glycan processing	MAN2A1 GANAB ST8SIA2 PRKCSH	1.07e-05	17	174	4	GO:0006491
GeneOntologyBiologicalProcess	cerebellar Purkinje cell differentiation	CACNA1A HERC1 ATP2B2 AGTPBP1	1.37e-05	18	174	4	GO:0021702
GeneOntologyBiologicalProcess	cerebellar Purkinje cell layer formation	CACNA1A HERC1 ATP2B2 AGTPBP1	2.13e-05	20	174	4	GO:0021694
GeneOntologyBiologicalProcess	cerebellar Purkinje cell layer morphogenesis	CACNA1A HERC1 ATP2B2 AGTPBP1	5.39e-05	25	174	4	GO:0021692
GeneOntologyBiologicalProcess	lens epithelial cell proliferation	SOX11 FOXE3	7.08e-05	2	174	2	GO:0097166
GeneOntologyBiologicalProcess	positive regulation of lens epithelial cell proliferation	SOX11 FOXE3	7.08e-05	2	174	2	GO:2001111
GeneOntologyBiologicalProcess	regulation of lens epithelial cell proliferation	SOX11 FOXE3	7.08e-05	2	174	2	GO:2001109
GeneOntologyBiologicalProcess	basement membrane assembly	PLOD3 PHLDB1 PHLDB2	1.23e-04	12	174	3	GO:0070831
GeneOntologyBiologicalProcess	cell differentiation in hindbrain	CACNA1A HERC1 ATP2B2 AGTPBP1	1.46e-04	32	174	4	GO:0021533
GeneOntologyCellularComponent	glucosidase complex	GANAB PRKCSH	6.89e-05	2	174	2	GO:1902687
GeneOntologyCellularComponent	glucosidase II complex	GANAB PRKCSH	6.89e-05	2	174	2	GO:0017177
Domain	SPRY	TRIM14 BTN3A1 BTN2A1 RYR3 BTN3A3 BTN2A2 HERC1	1.69e-05	87	174	7	SM00449
Domain	DH_1	NET1 PLEKHG7 ARHGEF17 ARHGEF15 ARHGEF10L DNMBP	2.62e-05	63	174	6	PS00741
Domain	SPRY	TRIM14 BTN3A1 BTN2A1 RYR3 BTN3A3 BTN2A2 HERC1	2.80e-05	94	174	7	PF00622
Domain	SPRY_dom	TRIM14 BTN3A1 BTN2A1 RYR3 BTN3A3 BTN2A2 HERC1	2.80e-05	94	174	7	IPR003877
Domain	B30.2/SPRY	TRIM14 BTN3A1 BTN2A1 RYR3 BTN3A3 BTN2A2 HERC1	2.99e-05	95	174	7	IPR001870
Domain	B302_SPRY	TRIM14 BTN3A1 BTN2A1 RYR3 BTN3A3 BTN2A2 HERC1	2.99e-05	95	174	7	PS50188
Domain	RhoGEF	NET1 PLEKHG7 ARHGEF17 ARHGEF15 ARHGEF10L DNMBP	4.07e-05	68	174	6	SM00325
Domain	PRY	TRIM14 BTN3A1 BTN2A1 BTN3A3 BTN2A2	4.26e-05	42	174	5	PF13765
Domain	RhoGEF	NET1 PLEKHG7 ARHGEF17 ARHGEF15 ARHGEF10L DNMBP	4.80e-05	70	174	6	PF00621
Domain	DH_2	NET1 PLEKHG7 ARHGEF17 ARHGEF15 ARHGEF10L DNMBP	4.80e-05	70	174	6	PS50010
Domain	-	NET1 PLEKHG7 ARHGEF17 ARHGEF15 ARHGEF10L DNMBP	5.20e-05	71	174	6	1.20.900.10
Domain	DH-domain	NET1 PLEKHG7 ARHGEF17 ARHGEF15 ARHGEF10L DNMBP	5.20e-05	71	174	6	IPR000219
Domain	PRY	TRIM14 BTN3A1 BTN2A1 BTN3A3 BTN2A2	8.20e-05	48	174	5	SM00589
Domain	PRY	TRIM14 BTN3A1 BTN2A1 BTN3A3 BTN2A2	8.20e-05	48	174	5	IPR006574
Domain	-	TTC39B NRDE2 TTC28 NCF2 TRRAP XAB2 TOMM34 GPSM1 EDRF1	1.43e-04	207	174	9	1.25.40.10
Domain	TPR-like_helical_dom	TTC39B NRDE2 TTC28 NCF2 TRRAP XAB2 TOMM34 GPSM1 EDRF1	3.45e-04	233	174	9	IPR011990
Domain	AAA	VWA8 PEX1 HELZ2 NAV3 NAV2 ABCC12 DYNC1H1	4.07e-04	144	174	7	SM00382
Domain	AAA+_ATPase	VWA8 PEX1 HELZ2 NAV3 NAV2 ABCC12 DYNC1H1	4.07e-04	144	174	7	IPR003593
Domain	Butyrophylin	TRIM14 BTN3A1 BTN2A1 BTN3A3 BTN2A2	4.92e-04	70	174	5	IPR003879
Domain	ATP_Ca_trans_C	ATP2B1 ATP2B2	5.11e-04	4	174	2	IPR022141
Domain	ATP_Ca_trans_C	ATP2B1 ATP2B2	5.11e-04	4	174	2	PF12424
Domain	P-type_ATPase_IIB	ATP2B1 ATP2B2	5.11e-04	4	174	2	IPR006408
Domain	-	LRCH2 EHBP1L1 NAV3 NAV2 CAMSAP2	5.25e-04	71	174	5	1.10.418.10
Domain	C2-set_2	BTN3A1 BTN2A1 BTN2A2 SIGLEC1	5.63e-04	41	174	4	PF08205
Domain	CD80_C2-set	BTN3A1 BTN2A1 BTN2A2 SIGLEC1	5.63e-04	41	174	4	IPR013162
Domain	Cation_ATPase_N	ATP13A5 ATP2B1 ATP2B2	5.85e-04	18	174	3	PF00690
Domain	Cation_ATPase_N	ATP13A5 ATP2B1 ATP2B2	5.85e-04	18	174	3	SM00831
Domain	CH	LRCH2 EHBP1L1 NAV3 NAV2 CAMSAP2	5.97e-04	73	174	5	PS50021
Domain	CH-domain	LRCH2 EHBP1L1 NAV3 NAV2 CAMSAP2	6.75e-04	75	174	5	IPR001715
Domain	ATPase_P-typ_cation-transptr_N	ATP13A5 ATP2B1 ATP2B2	6.90e-04	19	174	3	IPR004014
Domain	ConA-like_dom	TRIM14 BTN3A1 BTN2A1 RYR3 BTN3A3 BTN2A2 HERC1 USH2A	1.05e-03	219	174	8	IPR013320
Domain	TPR	TTC39B TTC28 NCF2 XAB2 TOMM34 GPSM1	1.33e-03	129	174	6	SM00028
Pathway	REACTOME_BUTYROPHILIN_BTN_FAMILY_INTERACTIONS	BTN3A1 BTN2A1 BTN3A3 BTN2A2	2.76e-06	12	125	4	M27738
Pathway	WP_PKCGAMMA_CALCIUM_SIGNALING_IN_ATAXIA	CACNA1A RYR3 PLCB3 ATP2B2	3.81e-05	22	125	4	M39795
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	DPH2 NDST1 PNPLA2 PLOD3 NUP85 VWA8 MYOM3 APEH CARD10 TRRAP AHDC1 ARHGEF10L KMT2C JUNB PHLDB1 EHBP1L1 TRIM28 HELZ2 NAV2 PDZD8 DOT1L HERC1 DNMBP DYNC1H1 CREB3	7.61e-10	1105	181	25	35748872
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	DIP2B NRDE2 NUP85 RNF31 TTC28 PEX1 TFIP11 FHIP2A NSUN2 XAB2 RUSC2 FREM2 RBM14 DOCK7 PLCB3 EDEM1 ZBED1 DDX11L8	1.03e-08	650	181	18	38777146
Pubmed	BTN1A1, the mammary gland butyrophilin, and BTN2A2 are both inhibitors of T cell activation.	BTN3A1 BTN2A1 BTN3A3 BTN2A2	1.06e-08	6	181	4	20208008
Pubmed	The cluster of BTN genes in the extended major histocompatibility complex.	BTN3A1 BTN2A1 BTN3A3 BTN2A2	2.45e-08	7	181	4	11170752
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	LRCH2 TTC28 FHIP2A ARHGEF17 EPG5 RUSC2 CRACD PHLDB1 GANAB DOCK7 NAV3 CAMSAP2 DYNC1H1 AGTPBP1	3.42e-08	407	181	14	12693553
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	ATXN2L DIP2B HIPK4 TTC28 NET1 DSP CEP162 ARHGEF17 RUSC2 PHLDB1 TBC1D4 RBM14 DOCK7 NAV2 DNMBP CAMSAP2 ATP2B1 EDRF1 PHLDB2	1.41e-07	861	181	19	36931259
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	NRDE2 ATP6AP1 PLOD3 SUPT20H MAN2A1 NET1 ARHGAP10 NTHL1 TFIP11 TRRAP AHDC1 DDX27 XAB2 CRACD KMT2C JUNB HELZ2 UTP20 TAF4 HEATR5B DNMBP CAMSAP2 EDRF1 MOV10 KIF22	2.84e-07	1497	181	25	31527615
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	SOX11 TTC39B NUP85 VWA8 RBM12B DSP CYP27A1 PEX1 CARD10 TRRAP NSUN2 ARHGEF15 PHLDB1 BRCA2 DYNC1H1 MOV10 TANGO6	4.93e-07	754	181	17	35906200
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	DIP2B NRDE2 SUPT20H LRCH2 VWA8 RBM12B DSP TFIP11 TRRAP AHDC1 XAB2 EHBP1L1 GANAB TRIM28 CYB5R3 HELZ2 RBM14 DOCK7 DDX3Y DYNC1H1	1.05e-06	1082	181	20	38697112
Pubmed	SENP3 regulates the global protein turnover and the Sp1 level via antagonizing SUMO2/3-targeted ubiquitination and degradation.	TRRAP NSUN2 DDX27 XAB2 GANAB TRIM28	1.07e-06	64	181	6	26511642
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	NUP85 RBM12B DSP TRRAP NSUN2 DDX27 XAB2 PHLDB1 GANAB TRIM28 RBM14 DOCK7 UTP20 PRKCSH HEATR5B ATP2B1 DYNC1H1 PHLDB2 KIF22	1.88e-06	1024	181	19	24711643
Pubmed	A 1.1-Mb transcript map of the hereditary hemochromatosis locus.	BTN3A1 BTN2A1 BTN3A3 BTN2A2	2.05e-06	18	181	4	9149941
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	ATXN2L DIP2B DSP TFIP11 TRRAP NSUN2 JUNB TBC1D4 TRIM28 HELZ2 RBM14 UTP20 PLCB3 DNMBP AGTPBP1 PHLDB2	3.30e-06	774	181	16	15302935
Pubmed	Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation.	LRCH2 APEH DHRS7B PPP1R8 GANAB TBC1D4 CYB5R3 RBM14 DOCK7 TOMM34 PRKCSH ATP2B1 DYNC1H1	5.06e-06	534	181	13	35032548
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	SUPT20H RNF31 TTC28 NET1 VWA8 ARHGAP10 BTBD18 PEX1 TRRAP SLC4A1 DHRS7B ZNF469 HMCN2 TRIM28 GLI3 SIGLEC1 TAF4 AGTPBP1 PHLDB2	6.47e-06	1116	181	19	31753913
Pubmed	RAD21 cooperates with pluripotency transcription factors in the maintenance of embryonic stem cell identity.	ATXN2L NSUN2 AHDC1 DDX27 TRIM28 RBM14 MOV10	1.21e-05	146	181	7	21589869
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	PLOD3 SUPT20H TFIP11 BEND4 TRRAP RYR3 KMT2C PHLDB1 NAV2 RP1 TAF4 HERC1	1.28e-05	497	181	12	36774506
Pubmed	EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.	ATP6AP1 PLOD3 DSP CEP162 APEH NSUN2 GANAB TRIM28 CYB5R3 UGP2 HELZ2 DDX3Y PRKCSH DYNC1H1 MOV10	2.22e-05	803	181	15	36517590
Pubmed	Laminin-based cell adhesion anchors microtubule plus ends to the epithelial cell basal cortex through LL5alpha/beta.	PHLDB1 PHLDB2	2.69e-05	2	181	2	20513769
Pubmed	Phosphoantigens glue butyrophilin 3A1 and 2A1 to activate Vγ9Vδ2 T cells.	BTN3A1 BTN2A1	2.69e-05	2	181	2	37674084
Pubmed	RNA cytosine methylation by Dnmt2 and NSun2 promotes tRNA stability and protein synthesis.	NSUN2 TRDMT1	2.69e-05	2	181	2	22885326
Pubmed	Cerebellar mutations affecting the postnatal survival of Purkinje cells in the mouse disclose a longitudinal pattern of differentially sensitive cells.	HERC1 AGTPBP1	2.69e-05	2	181	2	3678603
Pubmed	The RAD52 S346X variant reduces risk of developing breast cancer in carriers of pathogenic germline BRCA2 mutations.	RAD52 BRCA2	2.69e-05	2	181	2	32175645
Pubmed	Structure and evolution of the extended B7 family.	BTN3A3 BTN2A2	2.69e-05	2	181	2	10354554
Pubmed	Tottering mouse motor dysfunction is abolished on the Purkinje cell degeneration (pcd) mutant background.	CACNA1A AGTPBP1	2.69e-05	2	181	2	10630211
Pubmed	The alpha- and beta-subunits are required for expression of catalytic activity in the hetero-dimeric glucosidase II complex from human liver.	GANAB PRKCSH	2.69e-05	2	181	2	10764838
Pubmed	Two distinct domains of the beta-subunit of glucosidase II interact with the catalytic alpha-subunit.	GANAB PRKCSH	2.69e-05	2	181	2	10764837
Pubmed	Chromosomal localization of the neurological mouse mutations tottering (tg), Purkinje cell degeneration (pcd), and nervous (nr).	CACNA1A AGTPBP1	2.69e-05	2	181	2	8738138
Pubmed	Structures of mammalian ER α-glucosidase II capture the binding modes of broad-spectrum iminosugar antivirals.	GANAB PRKCSH	2.69e-05	2	181	2	27462106
Pubmed	Coexpression of EphA10 and Gli3 promotes breast cancer cell proliferation, invasion and migration.	GLI3 EPHA10	2.69e-05	2	181	2	33990369
Pubmed	Alternative splicing of transcripts encoding the alpha- and beta-subunits of mouse glucosidase II in T lymphocytes.	GANAB PRKCSH	2.69e-05	2	181	2	10024665
Pubmed	Ligand-induced interactions between butyrophilin 2A1 and 3A1 internal domains in the HMBPP receptor complex.	BTN3A1 BTN2A1	2.69e-05	2	181	2	35081362
Pubmed	Rad52 inactivation is synthetically lethal with BRCA2 deficiency.	RAD52 BRCA2	2.69e-05	2	181	2	21148102
Pubmed	Human RAD52 protein regulates homologous recombination and checkpoint function in BRCA2 deficient cells.	RAD52 BRCA2	2.69e-05	2	181	2	30590106
Pubmed	Mutations to the BTN2A1 Linker Region Impact Its Homodimerization and Its Cytoplasmic Interaction with Phospho-Antigen-Bound BTN3A1.	BTN3A1 BTN2A1	2.69e-05	2	181	2	37171180
Pubmed	A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.	LRCH2 GDAP2 PEX1 TBC1D4 GLI3 DOCK7 DYNC1H1 MOV10	3.15e-05	232	181	8	25515538
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	ATXN2L TTC28 DSP TFIP11 TRRAP DHRS7B KMT2C TRIM28 DOCK7 TAF4 DOT1L DYNC1H1	3.38e-05	549	181	12	38280479
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	RELCH ATP6AP1 PLOD3 DSP ARHGAP10 CEP162 DDX27 PPP1R8 GANAB TBC1D4 PTPRN2 PDZD8 PRKCSH HERC1 ATP2B1 AGTPBP1 KIF22	3.77e-05	1049	181	17	27880917
Pubmed	Getting in and out from calnexin/calreticulin cycles.	GANAB PRKCSH EDEM1	3.82e-05	13	181	3	18303019
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	ATXN2L DSP NTHL1 NSUN2 DDX27 GANAB TRIM28 RBM14 DOCK7 UTP20 DDX3Y MRPL36 TAF4 DYNC1H1 MOV10 KIF22	4.03e-05	949	181	16	36574265
Pubmed	Mutation of ARHGAP9 in patients with coronary spastic angina.	ARHGAP10 ARHGEF17 ARHGEF15 ARHGEF10L	4.56e-05	38	181	4	19911011
Pubmed	Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.	CACNA1A RYR3 ATP2B1 ATP2B2	4.56e-05	38	181	4	30786075
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	NR2C2 NUP85 DSP ARHGAP10 BEND4 TRRAP CRACD JUNB TBC1D4 UTP20 ATP2B1 DYNC1H1 AGTPBP1 MOV10 KIF22	4.65e-05	857	181	15	25609649
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	CACNA1A ATXN2L DENND2A ATP6AP1 LRCH2 DSP ARHGEF17 SLC4A1 CRACD PHLDB1 TRIM28 UGP2 RBM14 DOCK7 DDX3Y CAMSAP2 ATP2B1 ATP2B2 DYNC1H1 AGTPBP1	6.13e-05	1431	181	20	37142655
Pubmed	The cell proliferation antigen Ki-67 organises heterochromatin.	NR2C2 NUP85 ARHGAP10 TFIP11 TRRAP DDX27 DOCK7 UTP20 DNMBP MOV10	6.28e-05	410	181	10	26949251
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	TTC28 VWA8 XAB2 TBC1D4 PTPRN2 TANGO6	6.39e-05	130	181	6	12421765
Pubmed	Proteome-wide analysis of phospho-regulated PDZ domain interactions.	NET1 HEATR5B ATP2B1 ATP2B2	6.80e-05	42	181	4	30126976
Pubmed	Identification of the CD45-associated 116-kDa and 80-kDa proteins as the alpha- and beta-subunits of alpha-glucosidase II.	GANAB PRKCSH	8.05e-05	3	181	2	9148925
Pubmed	Target neuron controls the integrity of afferent axon phenotype: a study on the Purkinje cell-climbing fiber system in cerebellar mutant mice.	HERC1 AGTPBP1	8.05e-05	3	181	2	7891151
Pubmed	Trafficking of presynaptic PMCA signaling complexes in mouse photoreceptors requires Cav1.4 α1 subunits.	ATP2B1 ATP2B2	8.05e-05	3	181	2	22183401
Pubmed	Protein kinase C phosphorylates the carboxyl terminus of the plasma membrane Ca(2+)-ATPase from human erythrocytes.	ATP2B1 ATP2B2	8.05e-05	3	181	2	1827443
Pubmed	Plasma membrane Ca2+ ATPase isoform 2b interacts preferentially with Na+/H+ exchanger regulatory factor 2 in apical plasma membranes.	ATP2B1 ATP2B2	8.05e-05	3	181	2	11786550
Pubmed	Butyrophilin 2a2 (Btn2a2) expression on thymic epithelial cells promotes central T cell tolerance and prevents autoimmune disease.	BTN2A1 BTN2A2	8.05e-05	3	181	2	37356345
Pubmed	Differential alterations in expressions of ryanodine receptor subtypes in cerebellar cortical neurons of an ataxic mutant, rolling mouse Nagoya.	CACNA1A RYR3	8.05e-05	3	181	2	18313230
Pubmed	Plasma Membrane Calcium ATPase-Neuroplastin Complexes Are Selectively Stabilized in GM1-Containing Lipid Rafts.	ATP2B1 ATP2B2	8.05e-05	3	181	2	34948386
Pubmed	RANKL-Induced Btn2a2 - A T Cell Immunomodulatory Molecule - During Osteoclast Differentiation Fine-Tunes Bone Resorption.	BTN2A1 BTN2A2	8.05e-05	3	181	2	34421818
Pubmed	FROUNT is a common regulator of CCR2 and CCR5 signaling to control directional migration.	NUP85 CCR5	8.05e-05	3	181	2	19841162
Pubmed	Targeting FROUNT with disulfiram suppresses macrophage accumulation and its tumor-promoting properties.	NUP85 CCR5	8.05e-05	3	181	2	32001710
Pubmed	DSS1 interacts with and stimulates RAD52 to promote the repair of DSBs.	RAD52 BRCA2	8.05e-05	3	181	2	31799622
Pubmed	Conserved region I of human coactivator TAF4 binds to a short hydrophobic motif present in transcriptional regulators.	TAF4 CREB3	8.05e-05	3	181	2	17483474
Pubmed	Neuron navigator: a human gene family with homology to unc-53, a cell guidance gene from Caenorhabditis elegans.	NAV3 NAV2	8.05e-05	3	181	2	12079279
Pubmed	Sensory deficits in mice hypomorphic for a mammalian homologue of unc-53.	NAV3 NAV2	8.05e-05	3	181	2	15158073
Pubmed	Identification of a binding element for the cytoplasmic regulator FROUNT in the membrane-proximal C-terminal region of chemokine receptors CCR2 and CCR5.	NUP85 CCR5	8.05e-05	3	181	2	24128342
Pubmed	Pore membrane and/or filament interacting like protein 1 (POMFIL1) is predominantly expressed in the nervous system and encodes different protein isoforms.	NAV3 NAV2	8.05e-05	3	181	2	12062803
Pubmed	Key implication of CD277/butyrophilin-3 (BTN3A) in cellular stress sensing by a major human γδ T-cell subset.	BTN3A1 BTN3A3	8.05e-05	3	181	2	22767497
Pubmed	The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.	CYLC2 ATXN2L TFIP11 GANAB RBM14 DDX3Y ATP2B1	8.23e-05	197	181	7	20811636
Pubmed	Characterization of long cDNA clones from human adult spleen. II. The complete sequences of 81 cDNA clones.	RNF31 SHE DOT1L	8.93e-05	17	181	3	12693554
Pubmed	Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals.	NDST1 ITPK1 PTPRN2 TAF4 SDK1 TRDMT1	1.04e-04	142	181	6	19851296
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	ATXN2L PLOD3 NUP85 RBM12B DSP TRIM14 NSUN2 DDX27 XAB2 DHRS7B TRIM28 HELZ2 RBM14 DOCK7 UTP20 DYNC1H1 MOV10 PHLDB2	1.08e-04	1257	181	18	36526897
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	DSP MYOM3 ARHGEF17 KMT2C FREM2 TBC1D4 PTPRN2 DQX1 SCN3A UTP20 PLCB3 TUBE1 DYNC1H1	1.38e-04	736	181	13	29676528
Pubmed	Defining the membrane proteome of NK cells.	ATXN2L DIP2B MAN2A1 NUP85 XAB2 DHRS7B BTN3A3 EHBP1L1 GANAB CYB5R3 HELZ2 TOMM34 PDZD8 DDX3Y HEATR5B ATP2B1 DYNC1H1	1.39e-04	1168	181	17	19946888
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	KNTC1 NRDE2 DSP CEP162 NTHL1 TRRAP DDX27 PPP1R8 KMT2C GANAB TBC1D4 TRIM28 UGP2 HAS1 HERC1 EDEM1 DYNC1H1 MOV10	1.40e-04	1284	181	18	17353931
Pubmed	Rad52 gene mutations in breast/ovarian cancer families and sporadic ovarian carcinoma patients.	RAD52 BRCA2	1.61e-04	4	181	2	12883740
Pubmed	Cell-specific expression of plasma membrane calcium ATPase isoforms in retinal neurons.	ATP2B1 ATP2B2	1.61e-04	4	181	2	12209837
Pubmed	Btn2a2 Regulates ILC2-T Cell Cross Talk in Type 2 Immune Responses.	BTN2A1 BTN2A2	1.61e-04	4	181	2	35145516
Pubmed	N-Acetylglucosaminyl transferase regulates the expression of the sulfoglucuronyl glycolipids in specific cell types in cerebellum during development.	CACNA1A AGTPBP1	1.61e-04	4	181	2	8910533
Pubmed	Expression and role of calcium-ATPase pump and sodium-calcium exchanger in differentiated trophoblasts from human term placenta.	ATP2B1 ATP2B2	1.61e-04	4	181	2	12784250
Pubmed	Endoplasmic reticulum glucosidase II is composed of a catalytic subunit, conserved from yeast to mammals, and a tightly bound noncatalytic HDEL-containing subunit.	GANAB PRKCSH	1.61e-04	4	181	2	8910335
Pubmed	The plasma membrane calcium pump in health and disease.	ATP2B1 ATP2B2	1.61e-04	4	181	2	23413890
Pubmed	PSD95beta regulates plasma membrane Ca2+ pump localization at the photoreceptor synapse.	ATP2B1 ATP2B2	1.61e-04	4	181	2	19233278
Pubmed	Quantitative analysis of alternative splicing options of human plasma membrane calcium pump genes.	ATP2B1 ATP2B2	1.61e-04	4	181	2	8245032
Pubmed	Cloning, localization, and structure of new members of the butyrophilin gene family in the juxta-telomeric region of the major histocompatibility complex.	BTN3A1 BTN2A1	1.61e-04	4	181	2	9382921
Pubmed	Panel-based NGS Reveals Novel Pathogenic Mutations in Autosomal Recessive Retinitis Pigmentosa.	RP1 USH2A	1.61e-04	4	181	2	26806561
Pubmed	Quantitative analysis of alternative splicing options of human plasma membrane calcium pump genes.	ATP2B1 ATP2B2	1.61e-04	4	181	2	7989379
Pubmed	Role of alternative splicing in generating isoform diversity among plasma membrane calcium pumps.	ATP2B1 ATP2B2	1.61e-04	4	181	2	11152753
Pubmed	RAD52 aptamer regulates DNA damage repair and STAT3 in BRCA1/BRCA2‑deficient human acute myeloid leukemia.	RAD52 BRCA2	1.61e-04	4	181	2	32945515
Pubmed	Primate-specific BTN3A2 protects against SARS-CoV-2 infection by interacting with and reducing ACE2.	BTN3A1 BTN3A3	1.61e-04	4	181	2	39142074
Pubmed	PMCA1 depletion in mouse eggs amplifies calcium signaling and impacts offspring growth†.	ATP2B1 ATP2B2	1.61e-04	4	181	2	36130203
Pubmed	Developmental expression of the four plasma membrane calcium ATPase (Pmca) genes in the mouse.	ATP2B1 ATP2B2	1.61e-04	4	181	2	10434059
Pubmed	Btn2a2, a T cell immunomodulatory molecule coregulated with MHC class II genes.	BTN2A1 BTN2A2	1.61e-04	4	181	2	26809444
Pubmed	E3 ubiquitin ligase RNF31 cooperates with DAX-1 in transcriptional repression of steroidogenesis.	RNF31 NR0B2	1.61e-04	4	181	2	19237537
Pubmed	Adeno-associated virus Rep proteins antagonize phosphatase PP1 to counteract KAP1 repression of the latent viral genome.	PPP1R8 TRIM28	1.61e-04	4	181	2	29581310
Pubmed	Calcium pumps of plasma membrane and cell interior.	ATP2B1 ATP2B2	1.61e-04	4	181	2	15101689
Pubmed	[Elevated immunoreactive-somatostatin levels in the brain of ataxic mutant mice].	CACNA1A AGTPBP1	1.61e-04	4	181	2	2901364
Pubmed	Butyrophilin Btn2a2 inhibits TCR activation and phosphatidylinositol 3-kinase/Akt pathway signaling and induces Foxp3 expression in T lymphocytes.	BTN2A1 BTN2A2	1.61e-04	4	181	2	23589618
Pubmed	Plasma membrane calcium ATPases as critical regulators of calcium homeostasis during neuronal cell function.	ATP2B1 ATP2B2	1.61e-04	4	181	2	10577388
Pubmed	Structural organization, ion transport, and energy transduction of P-type ATPases.	ATP2B1 ATP2B2	1.61e-04	4	181	2	8634322
Pubmed	Timeless Maintains Genomic Stability and Suppresses Sister Chromatid Exchange during Unperturbed DNA Replication.	RAD52 BRCA2	1.61e-04	4	181	2	19112184
Pubmed	Mapping of synapsin II (SYN2) genes to human chromosome 3p and mouse chromosome 6 band F.	RAD52 ATP2B2	1.61e-04	4	181	2	7587399
Pubmed	Liprin-α1, ERC1 and LL5 define polarized and dynamic structures that are implicated in cell migration.	PHLDB1 PHLDB2	1.61e-04	4	181	2	24982445
Interaction	DNAJC3 interactions	PLOD3 ANPEP NSUN2 CFD GANAB TRIM28 PLCB3 PRKCSH EDEM1 CAMSAP2 EPHA10	4.48e-06	226	174	11	int:DNAJC3
Interaction	CDC37 interactions	RNF32 NR2C2 RNF31 HIPK4 ARHGAP10 CARD10 RIPK4 TRIM14 NSUN2 CSF1R TRIM28 RBM14 TOMM34 PDZD8 PRKCSH ZBED1 MOV10 SBK2	1.26e-05	645	174	18	int:CDC37
Interaction	C6orf141 interactions	LRCH2 DSP PEX1 TBC1D4 BRCA2 EDRF1 TANGO6	1.50e-05	92	174	7	int:C6orf141
GeneFamily	Butyrophilins\|V-set domain containing\|C2-set domain containing	BTN3A1 BTN2A1 BTN3A3 BTN2A2	2.46e-06	15	121	4	458
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	NET1 ARHGEF17 ARHGEF15 ARHGEF10L DNMBP	7.97e-05	66	121	5	722
GeneFamily	C2-set domain containing\|Immunoglobulin like domain containing\|Scavenger receptors	BTN3A1 BTN2A1 BTN2A2 SIGLEC1	1.45e-04	40	121	4	592
GeneFamily	Olfactory receptors, family 2	OR2W1 OR2AG2 OR2T6 OR2Y1 OR2AG1	9.75e-04	113	121	5	149
GeneFamily	Tetratricopeptide repeat domain containing\|Bardet-Biedl syndrome associated\|BBSome	TTC39B TTC28 NCF2 TOMM34 GPSM1	1.06e-03	115	121	5	769
GeneFamily	ATPases Ca2+ transporting	ATP2B1 ATP2B2	1.55e-03	9	121	2	1209
GeneFamily	UPF1 like RNA helicases	HELZ2 MOV10	2.35e-03	11	121	2	1169
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DENND2A TTC28 CYP21A2 CFD PHLDB1 HMCN2 GLI3 NAV3 HAS1 PHLDB2	7.89e-09	195	181	10	ff0aa455e9844a6d7ae57ff59fb6cea825cf1fc2
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1A TTC28 KMT2C PTPRN2 NAV2 DDX3Y HERC1 ATP2B1 DYNC1H1 PHLDB2	7.89e-09	195	181	10	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1A TTC28 KMT2C PTPRN2 NAV2 DDX3Y HERC1 ATP2B1 DYNC1H1 PHLDB2	7.89e-09	195	181	10	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CLCA4 BARX2 ARHGEF10L PSMG2 RAPGEF3 TMEM178A SCN3A SDK1	3.42e-07	162	181	8	285e6d553f485fd9f1075c4e1b940da251b5ea35
ToppCell	Children_(3_yrs)-Mesenchymal-pericyte_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SOX11 DENND2A ARHGAP10 SAMD5 ARHGEF17 PKNOX2 PHLDB1 CSF1R	1.01e-06	187	181	8	86250acf088ec0c4800a0dfa031b0d4f7e52c342
ToppCell	B_cells-ISG-high_B_cells\|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis	CACNA1A TTC39B DSP PLEKHG7 USP25 TRIM14 HELZ2 MOV10	1.39e-06	195	181	8	b64d9e1a8834401b4dc501566546647754ae21fc
ToppCell	distal-Hematologic-Alveolar_Macrophage-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	TTC39B ANPEP ARHGAP10 CYP27A1 NCF2 CFD SIGLEC1 ATP2B1	1.56e-06	198	181	8	e1dc5a56fc23d3b1b4350d7162acec5762115b64
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	BARX2 ARHGEF10L PSMG2 RAPGEF3 TMEM178A SCN3A SDK1	4.96e-06	164	181	7	6fb2136168f430babfeb81ca7e151ca7a8092ec4
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.5.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TTC39B ANPEP CYP27A1 NCF2 ARHGEF10L CFD SIGLEC1	7.32e-06	174	181	7	d5c22b43531414951666ee7542a66ed9380e2d14
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DENND2A LRCH2 DTX1 SCN3A NAV3 SHE PHLDB2	8.49e-06	178	181	7	ad3de3e03a401dac64431a541899445262246347
ToppCell	Children_(3_yrs)-Mesenchymal-pericyte_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DENND2A LRCH2 ARHGAP10 SAMD5 ARHGEF17 PKNOX2 PHLDB1	9.46e-06	181	181	7	451b87ac95154bb80018b8dd245b4a6389d81411
ToppCell	healthy_donor-Myeloid-Monocytic-SC_&_Eosinophil\|healthy_donor / Disease condition, Lineage, Cell class and subclass	LRCH2 ARHGEF17 RYR3 CRACD SYTL4 MED12L GPSM1	9.81e-06	182	181	7	6bd6c32c48fecd6d03ac8a09e405b3b99bdc12ae
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX11 RYR3 FREM2 NAV3 USH2A SDK1 EPHA10	1.05e-05	184	181	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX11 RYR3 FREM2 NAV3 USH2A SDK1 EPHA10	1.05e-05	184	181	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX11 RYR3 FREM2 NAV3 USH2A SDK1 EPHA10	1.05e-05	184	181	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar-Macro_c5-WDR74\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	ANPEP CARD10 NCF2 ARHGEF10L RUSC2 CFD CSF1R	1.09e-05	185	181	7	68edb1bb03ed221d49e583123ca4de14252d7bc5
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	BARX2 ARHGEF10L TMEM178A SCN3A DOCK7 SLC14A2 SDK1	1.25e-05	189	181	7	8ff3c3232eff9de4b5c9b22ecb82bc509d773f58
ToppCell	Macrophages-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	ANPEP NCF2 TRIM14 ARHGEF10L CFD EHBP1L1 CSF1R	1.25e-05	189	181	7	c05b4b565c0ce56dbb45fc9503654a2ec1a7e1e9
ToppCell	facs-Pancreas-Endocrine-24m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTC28 JUNB PTPRN2 NAV2 DDX3Y SARAF GPSM1	1.25e-05	189	181	7	010fdd70e9d0e21b856306a29ff877776a480319
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	BARX2 ARHGEF10L TMEM178A SCN3A DOCK7 SLC14A2 SDK1	1.30e-05	190	181	7	4836ea19308d2a96694f12ab0653b7ce7b101d2f
ToppCell	facs-Pancreas-Endocrine-24m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTC28 JUNB PTPRN2 NAV2 DDX3Y SARAF GPSM1	1.34e-05	191	181	7	a251b134f67a0a1ef3a42f50042f128a17f20b22
ToppCell	Adult-Immune-alveolar_macrophage_(MARCO_positive)-D122\|Adult / Lineage, Cell type, age group and donor	ANPEP ARHGAP10 CYP27A1 NCF2 TRIM14 ARHGEF10L SIGLEC1	1.43e-05	193	181	7	cc1b6d3bf56e4a88f6fe23dd036a83cf5538c958
ToppCell	facs-Brain_Myeloid-Hippocampus-3m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DIP2B CSF1R NAV3 MED12L PDZD8 CCR5 HAS1	1.43e-05	193	181	7	9c16032bc03df8760ae199e8f19fdafa4c3f1827
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PHLDB1 GLI3 NAV3 NAV2 HAS1 SDK1 PHLDB2	1.43e-05	193	181	7	261cafc167c86ab277be4ea7f08b0173e2dde26e
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SAMD5 PKNOX2 NAV3 NAV2 GPSM1 SDK1 PHLDB2	1.48e-05	194	181	7	e93de9428c986b8943fc169258847c650cfab0e5
ToppCell	COVID-19-Fibroblasts-Alveolar_FB\|COVID-19 / group, cell type (main and fine annotations)	DENND2A TTC28 SAMD5 PKNOX2 NAV3 NAV2 SDK1	1.53e-05	195	181	7	603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCell	Adult-Immune-alveolar_macrophage_(MARCO_positive)\|Adult / Lineage, Cell type, age group and donor	ANPEP ARHGAP10 CYP27A1 NCF2 ARHGEF10L SIGLEC1 ATP2B1	1.53e-05	195	181	7	55e25f702af19146a161861cfd15f40bbda1dc35
ToppCell	COVID-19-Fibroblasts-Intermediate_pathological_FB\|COVID-19 / group, cell type (main and fine annotations)	TTC28 PKNOX2 CRACD GLI3 NAV3 SDK1 PHLDB2	1.64e-05	197	181	7	f1c8936986123a3151140c374fcd62d6705c530b
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar-Macro_c1-C1QC\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	ANPEP CYP27A1 NCF2 ARHGEF10L CFD CSF1R SIGLEC1	1.69e-05	198	181	7	579a22199643440b98e381147779ced630d4ed66
ToppCell	10x5'-Lung\|World / Manually curated celltypes from each tissue	ANPEP CYP27A1 NCF2 ARHGEF10L CFD CSF1R SIGLEC1	1.69e-05	198	181	7	a5cbe60caadd5b975906ecbc4eaa9795e4ebf885
ToppCell	BLOOD--(3)_MNP-(3)_Intermediate_monocytes\|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	CYP27A1 CFD JUNB PSMG2 DDX3Y SARAF SIGLEC1	1.69e-05	198	181	7	70c3efd4f6026a6a6065be632160a265d9ecd1e4
ToppCell	BAL-Control-Myeloid-TRAM-TRAM2-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PNPLA2 ATP6AP1 ARHGAP10 CYP27A1 NCF2 JUNB CYB5R3	1.75e-05	199	181	7	b8dc5dc9fe3f52be11940d45959134b2a7575a8b
ToppCell	BAL-Control-Myeloid-TRAM-TRAM2-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	PNPLA2 ATP6AP1 ARHGAP10 CYP27A1 NCF2 JUNB CYB5R3	1.75e-05	199	181	7	bbf81fb20da8a28aac024207696c6ea00473a0df
ToppCell	Mesenchymal\|World / Lineage, Cell type, age group and donor	DENND2A TTC28 SAMD5 PKNOX2 GLI3 NAV3 SDK1	1.75e-05	199	181	7	4bac110c2b3609f6ee5d0e3275da0824a6240270
ToppCell	BAL-Control-Myeloid-TRAM-TRAM2\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	PNPLA2 ATP6AP1 ARHGAP10 CYP27A1 NCF2 JUNB CYB5R3	1.75e-05	199	181	7	90b20fce27739f28609d664475a197eea586e030
ToppCell	LPS_only-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_only / Treatment groups by lineage, cell group, cell type	DENND2A PKNOX2 CFD SYTL4 UGP2 SDK1 CREB3	1.75e-05	199	181	7	fde2b65afde69f402f1b7b056eaa266e9fd5b227
ToppCell	10x3'2.3-week_14-16-Endothelial-stroma-tip_EC\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	SOX11 SAMD5 CARD10 PALMD ARHGEF15 OIT3 SHE	1.75e-05	199	181	7	1c69395c9305b6ecb0a826d46c8e8ec95795ad6d
ToppCell	BAL-Control-Myeloid-TRAM-TRAM2\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PNPLA2 ATP6AP1 ARHGAP10 CYP27A1 NCF2 JUNB CYB5R3	1.75e-05	199	181	7	617fd53c799722879acd8f2fd69b331d82e7bdb9
ToppCell	Control-Myeloid-TRAM2\|Control / Disease group,lineage and cell class （2021.01.30）	PNPLA2 ATP6AP1 ARHGAP10 CYP27A1 NCF2 JUNB CYB5R3	1.75e-05	199	181	7	5a08184573e524ce0e2974eed9817354890830a9
ToppCell	Tracheal-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_arterial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	TTC28 MYOM3 PALMD ARHGEF15 RAPGEF3 SHE ATP2B2	1.81e-05	200	181	7	5ec31c1be6bcc4124e1489d136570f3de33cc2e9
ToppCell	Neuronal\|World / cells hierarchy compared to all cells using T-Statistic	CACNA1A PTPRN2 TMEM178A SCN3A HERC1 ATP2B1 ATP2B2	1.81e-05	200	181	7	48d801219bc771d6c7e151dc88ca4c179988de85
ToppCell	Tracheal-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DENND2A ARHGAP10 CFD NAV3 NAV2 GPSM1 PHLDB2	1.81e-05	200	181	7	c318d14bd6fd6f42c597eb55ac9e2f48008aeb9b
ToppCell	390C-Myeloid-Macrophage-SPP1+_Macrophage_3\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	DENND2A VWA8 CYP27A1 NCF2 CCR5 SLC14A2	3.33e-05	149	181	6	13b445c13bb8f31ff0876addd1baf969ae220ea3
ToppCell	390C-Myeloid-Macrophage-SPP1+_Macrophage_3\|390C / Donor, Lineage, Cell class and subclass (all cells)	ANPEP CYP27A1 NCF2 CSF1R CCR5 SLC14A2	3.72e-05	152	181	6	f717aae4882e9b67e5e40f4ef5b0d35f74a89165
ToppCell	3'_v3-blood-Lymphocytic_T_CD4-Tfh\|blood / Manually curated celltypes from each tissue	MAN2A1 SAMD5 JUNB TBC1D4 SHE SARAF	4.00e-05	154	181	6	5ff380205fa7ab97ba21f6512bc9e14c0fb320b6
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Macrophage\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ANPEP NCF2 RUSC2 CFD SIGLEC1 CAMSAP2	4.62e-05	158	181	6	1635a85fc73c544028418087f36d28957dd4f458
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Macrophage-macrophage,_alveolar\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ANPEP NCF2 RUSC2 CFD SIGLEC1 CAMSAP2	4.62e-05	158	181	6	80841dadfa53bcde36a3e486408a095f78e772eb
ToppCell	E18.5-samps-Endothelial-Mature_fetal_endothelial-endothelial_cells_B\|E18.5-samps / Age Group, Lineage, Cell class and subclass	CLCA4 CARD10 PALMD CHRNB2 USH2A NR0B2	5.49e-05	163	181	6	d6f9b7280c44d120df5a72dfc2ebb26ffbb5752b
ToppCell	P28-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CACNA1A NTHL1 ARHGEF17 KMT2C CSF1R SDK1	6.49e-05	168	181	6	8c8dbdbc7053f34e4ca0c5067af502fbea109fc1
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LRCH2 PALMD ARHGEF15 HMCN2 FAM216B ATP2B2	6.71e-05	169	181	6	c7fc3a8c44f07c557b60d469717b66e2f5863d38
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SAMD5 BARX2 TMEM178A SCN3A SLC14A2 SDK1	6.71e-05	169	181	6	0332f539a2f7d6dcd081a5d2f567290721f5a329
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP13A5 RYR3 SCN3A RP1 USH2A ATP2B2	6.71e-05	169	181	6	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	facs-Lung-nan-3m-Endothelial-Vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NDST1 MAN2A1 NET1 SAMD5 SYTL4 RAPGEF3	6.93e-05	170	181	6	8e1f757ed62218c0fb6525f49d142dd2cd29acf9
ToppCell	facs-Lung-nan-3m-Endothelial-vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NDST1 MAN2A1 NET1 SAMD5 SYTL4 RAPGEF3	6.93e-05	170	181	6	67d7e1da3ebd2d14cb2e67799e94d655027ed5c4
ToppCell	droplet-Fat-Scat-18m\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLOD3 NCF2 ARHGEF10L CFD CSF1R CCR5	7.39e-05	172	181	6	8a4a5ad65eec92ce4fa45c5aa01c28666307455b
ToppCell	368C-Myeloid-Macrophage-SPP1+_Macrophage\|368C / Donor, Lineage, Cell class and subclass (all cells)	ANPEP NCF2 ARHGEF10L CSF1R CCR5 SIGLEC1	7.64e-05	173	181	6	bba8265a58f8f5659dc7b9da2fe27b15033fce34
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Bcl6-Excitatory_Neuron.Slc17a7.Bcl6-Npnt_(Layer_5a)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	SSTR4 SLC4A1 TAS1R1 USH2A	7.90e-05	56	181	4	112a412816287423089c0333a42432a6ab4500dc
ToppCell	NS-moderate-d_0-4-Epithelial-Ionocyte\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	MAN2A1 CEL SAMD5 TBC1D4 NAV3 PHLDB2	8.13e-05	175	181	6	a1e0a15c69211d6db2edeb101476f0f6e08b90c8
ToppCell	COVID-mDC1-\|COVID / Condition, Cell_class and T cell subcluster	ANPEP NET1 CARD10 MED12L SHE FSBP	8.13e-05	175	181	6	83a95d6fc2ddf3ec53f05825bbc982fb8d2ccd15
ToppCell	COVID-mDC1\|COVID / Condition, Cell_class and T cell subcluster	ANPEP NET1 CARD10 MED12L SHE FSBP	8.13e-05	175	181	6	b9280444016e21c28131a61df65cc5c56d402412
ToppCell	facs-Diaphragm-Limb_Muscle-18m-Endothelial-nan\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PALMD SSTR4 ARHGEF15 RAPGEF3 PLCB3 MOV10	8.39e-05	176	181	6	a3f27b5d7edf2d396c085efbe35305cfa0afa565
ToppCell	droplet-Marrow-nan-21m-Myeloid-monocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLOD3 CYP27A1 ARHGEF10L JUNB CSF1R ATP2B1	8.66e-05	177	181	6	b860013f1fd397400a62d66ab521cfc81349ffe2
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANPEP CYP27A1 NCF2 CFD CSF1R SIGLEC1	8.93e-05	178	181	6	0b398656f26c4061b11ccf98908d0e2e1367585a
ToppCell	droplet-Kidney-KIDNEY-30m-Lymphocytic-Epcam____thick_ascending_tube_S_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KNTC1 RBM12B SAMD5 CNTD1 FSBP KIF22	9.21e-05	179	181	6	4166c4e1a8748a79ac6a11fd0b97c5344be2321b
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW23-Neuronal\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	SOX11 PALMD CRACD SCN3A ST8SIA2	9.44e-05	112	181	5	9c3fb470708e76a8f8a3cb9aa17ab130c60fee11
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SAMD5 BARX2 TMEM178A SCN3A DOCK7 SDK1	9.50e-05	180	181	6	788d5fbf688365b5d92d3aa19b9f8e9448f8be5a
ToppCell	droplet-Liver-nan-3m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTC28 ZFAND4 ARHGEF15 OIT3 SHE PHLDB2	9.79e-05	181	181	6	fcc94f04dae98b817ec06b282d2e887804d37ae5
ToppCell	droplet-Heart-nan-3m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DIP2B PALMD ARHGEF15 RAPGEF3 NAV3 SHE	9.79e-05	181	181	6	92d44892bb15771f0ab5fe61879b204b0acbd9b3
ToppCell	Control-Epithelial_cells-Airway_club\|Control / group, cell type (main and fine annotations)	ARHGAP40 LGSN FREM2 NAV2 RP1 SDK1	9.79e-05	181	181	6	c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-6_VIP_RGS16\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DENND2A CARD10 BTN3A1 CRACD FREM2 OR5C1	1.01e-04	182	181	6	724c33ad2fb525cbcfa5efa3362675eb42a5636d
ToppCell	droplet-Heart-nan-3m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DIP2B PALMD ARHGEF15 RAPGEF3 NAV3 SHE	1.01e-04	182	181	6	81279877b920b5a1bc991a07d3031d6458700fe3
ToppCell	5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SUPT20H LRCH2 TTC28 ARHGAP10 GPSM1 AGTPBP1	1.04e-04	183	181	6	5377b4fbd8fdfe68933b4c0965aa9525f7f31591
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Endothelial-leukocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAD52 DTX1 RYR3 EPG5 OIT3 SCN3A	1.04e-04	183	181	6	919c9861073d12fd12aecd7469b1478b13838c43
ToppCell	3'-Child09-12-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TTC28 PALMD ARHGEF15 RAPGEF3 SHE RP1	1.07e-04	184	181	6	842473fa415575441b595073a994b6d621169776
ToppCell	COVID-19-Fibroblasts-Adventitial_FB\|COVID-19 / group, cell type (main and fine annotations)	TTC28 GLI3 NAV3 NAV2 SDK1 PHLDB2	1.10e-04	185	181	6	a5aebf2b9b05b550d021272731d68af9a6b1229d
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	RAD52 NET1 ARHGAP10 JUNB SYTL4 CAMSAP2	1.14e-04	186	181	6	ed9b1a784f67e8a297e2a10993a6d97df60581ac
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DENND2A LRCH2 DTX1 SCN3A NAV3 PHLDB2	1.14e-04	186	181	6	20340a5b5cc7f07386498a4ef937d6fbc9e347c4
ToppCell	10x3'2.3-week_17-19-Endothelial-stroma-proliferating_EC\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	TTC28 CARD10 PALMD ARHGEF15 HMCN2 SHE	1.14e-04	186	181	6	a844d4f79e0ad5d6c60a4488ffd8f4f21b7eed04
ToppCell	pdx-Tumor_cells-T5\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	TTC39B CRACD FREM2 NAV2 ATP2B1 SDK1	1.17e-04	187	181	6	7e376831a11ee72ed87abcdac631ca46ae29c250
ToppCell	Control-Fibroblasts-Adventitial_FB\|Control / group, cell type (main and fine annotations)	DENND2A ARHGAP10 CFD PHLDB1 NAV3 HAS1	1.21e-04	188	181	6	706a26c372add839d947749f0521a0e1f5c9b0ec
ToppCell	Children_(3_yrs)-Mesenchymal-pericyte_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DENND2A LRCH2 SAMD5 ARHGEF17 PKNOX2 PHLDB1	1.21e-04	188	181	6	ee151792c7ac9afe820f1a281c6dab383799f358
ToppCell	facs-Pancreas-Endocrine-24m-Epithelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JUNB PTPRN2 CYB5R3 NAV2 DDX3Y SARAF	1.21e-04	188	181	6	63773854bf8430fb8229edb385b953a89833d08c
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	BARX2 ARHGEF10L TMEM178A SCN3A DOCK7 SLC14A2	1.21e-04	188	181	6	4154f4787483c7e076e87a187733a9f666742c3d
ToppCell	facs-Heart-RA-24m-Mesenchymal-ventricular_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DSP PLA2G4E RYR3 CRACD RP1 SBK2	1.24e-04	189	181	6	e758b264c0a47127e33e66c395cf5a3224c7305b
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DENND2A PLEKHG7 RYR3 TBC1D4 RAPGEF3 RP1	1.24e-04	189	181	6	e059be2965cca70ff5576df055d0af1775b76e00
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	BARX2 ARHGEF10L TMEM178A SCN3A DOCK7 SLC14A2	1.24e-04	189	181	6	90aae7e806882bebfad78a78e9a16cf56af3ecd4
ToppCell	LA-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	ARHGAP10 RYR3 ARHGEF10L HMCN2 SCN3A SDK1	1.24e-04	189	181	6	6b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCell	facs-Heart-RA-24m-Mesenchymal-ventricular_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DSP PLA2G4E RYR3 CRACD RP1 SBK2	1.24e-04	189	181	6	b98f60875b1a12b2ec9dc91889298ae57f98602f
ToppCell	nucseq-Mesenchymal-Myocytic-Myocytic_1-Pericyte\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	DENND2A ARHGAP10 SAMD5 ARHGEF17 PKNOX2 PHLDB1	1.28e-04	190	181	6	4eb92aef1ee868f4537483d19014d947b7684612
ToppCell	wk_08-11-Epithelial-Proximal_epithelial-intermediate_neuroendocrine\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	CACNA1A DSP CHRNB2 TMEM178A SCN3A NR0B2	1.28e-04	190	181	6	5f1863bce9400b7c932f0e4d0e012ec4e8d7e555
ToppCell	nucseq-Mesenchymal-Myocytic-Myocytic_1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	DENND2A ARHGAP10 SAMD5 ARHGEF17 PKNOX2 PHLDB1	1.28e-04	190	181	6	7be4341e2909101d756f14031c21e705eb45e69a
ToppCell	10x5'v1-week_12-13-Endothelial-stroma-tip_EC\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	SOX11 CARD10 PALMD ARHGEF15 OIT3 SHE	1.31e-04	191	181	6	cf1a67b7c0d5c0dc5d4d59faf9d9b1a3a1fb00e0
ToppCell	PCW_07-8.5-Endothelial-Endothelial_mature-endo_venous_(13)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ANPEP CARD10 PALMD ARHGEF15 NAV3 SHE	1.31e-04	191	181	6	54029b68fb78163c969890886ab0f8fb0dcf3c20
ToppCell	Control-Myeloid-Macrophage_Alveolar\|Myeloid / Disease state, Lineage and Cell class	TTC39B VWA8 CYP27A1 USP25 CFD HEATR5B	1.31e-04	191	181	6	a7bb8aba9c59c037d995a77928cc7b4d5cbb82b9
ToppCell	COVID-19-lung-Macrophage_PPARGhi_CD5Lhi\|lung / Disease (COVID-19 only), tissue and cell type	ANPEP ARHGAP10 CYP27A1 NCF2 ARHGEF10L SIGLEC1	1.31e-04	191	181	6	dab953682b8c9ed680a799161f837f792a7e4f33
ToppCell	Adult-Immune-alveolar_macrophage_(MARCO_positive)-D175\|Adult / Lineage, Cell type, age group and donor	ANPEP ARHGAP10 CYP27A1 NCF2 ARHGEF10L EHBP1L1	1.35e-04	192	181	6	733491e932350e3c216a626cc49c3cd3fe970a82
ToppCell	BAL-Mild\|BAL / Compartment, Disease Groups and Clusters	CACNA1A BRCA2 HELZ2 SIGLEC1 ZBED1 MOV10	1.35e-04	192	181	6	1a6cbf014d3f7a3fb6f53adab078c4742e7137de
ToppCell	facs-Brain_Myeloid-Hippocampus-3m-Myeloid\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DIP2B CSF1R NAV3 PDZD8 CCR5 HAS1	1.39e-04	193	181	6	06b65110db974f4ef90d3511ff34428976a52c9c
ToppCell	facs-Brain_Myeloid-Hippocampus-3m\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DIP2B CSF1R NAV3 PDZD8 CCR5 HAS1	1.39e-04	193	181	6	a4f91bca5eaa985982d33a528f7566ffde154d47
ToppCell	3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.5.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CYP27A1 NCF2 ARHGEF10L CFD TBC1D4 SIGLEC1	1.39e-04	193	181	6	222829c30ebe47f0ed1e035897e3cd4be10b2a11
Disease	Hypopigmentation disorder	EPG5 GLI3	1.01e-04	3	172	2	C0162835
Disease	cholesterol:total lipids ratio, low density lipoprotein cholesterol measurement	TTC39B CYP21A2 EHBP1L1 DOCK7 SHE PLCB3	2.06e-04	144	172	6	EFO_0004611, EFO_0020943
Disease	polycystic liver disease (is_implicated_in)	GANAB PRKCSH	3.34e-04	5	172	2	DOID:0050770 (is_implicated_in)
Disease	facial pigmentation measurement	LINC01559 CEL BARX2 AGTPBP1	3.46e-04	57	172	4	EFO_0006942
Disease	Hailey-Hailey disease (implicated_via_orthology)	ATP2B1 ATP2B2	4.99e-04	6	172	2	DOID:0050429 (implicated_via_orthology)
Disease	glucosidase 2 subunit beta measurement	GANAB PRKCSH	4.99e-04	6	172	2	EFO_0801628
Disease	retinitis pigmentosa (implicated_via_orthology)	EPG5 USH2A AGTPBP1	5.14e-04	27	172	3	DOID:10584 (implicated_via_orthology)
Disease	cholesteryl ester 14:0 measurement	PTPRN2 SCN3A NAV3	5.14e-04	27	172	3	EFO_0010340
Disease	infertility (implicated_via_orthology)	CSF1R BRCA2	6.96e-04	7	172	2	DOID:5223 (implicated_via_orthology)
Disease	helping behavior measurement	BEND4 USH2A	9.24e-04	8	172	2	EFO_0008538
Disease	calpastatin measurement	SIGLEC1 DNMBP	9.24e-04	8	172	2	EFO_0008065
Disease	Polycystic Kidney, Type 1 Autosomal Dominant Disease	GANAB PRKCSH	9.24e-04	8	172	2	C0887850
Disease	tumor necrosis factor receptor superfamily member 19L measurement	ARHGEF17 CFD	9.24e-04	8	172	2	EFO_0008309
Disease	serine measurement	CYP21A2 SCN3A DYNC1H1	1.11e-03	35	172	3	EFO_0009774
Disease	Abnormality of the face	FHIP2A UGP2	1.18e-03	9	172	2	C4025871
Disease	cystic fibrosis (implicated_via_orthology)	ABCC12 EDEM1	1.18e-03	9	172	2	DOID:1485 (implicated_via_orthology)
Disease	X-21467 measurement	CYP21A2 DNMBP	1.18e-03	9	172	2	EFO_0020007
Disease	Intellectual Disability	NDST1 FHIP2A TRRAP NSUN2 KMT2C SCN3A UGP2 MED12L DYNC1H1	1.30e-03	447	172	9	C3714756
Disease	platelet component distribution width	DENND2A SUPT20H CYP21A2 VWA7 ARHGEF15 SYTL4 RAPGEF3 CYB5R3 DOCK7 SIGLEC1 HERC1 TRDMT1	1.65e-03	755	172	12	EFO_0007984
Disease	autosomal dominant nonsyndromic deafness (is_implicated_in)	ATP2B2 EPHA10	1.79e-03	11	172	2	DOID:0050564 (is_implicated_in)
Disease	cognitive function measurement	KNTC1 ATXN2L LINC01559 MAN2A1 CEL TTC28 DSP BARX2 SSTR4 RYR3 GANAB PTPRN2 GLI3 OR2Y1 MED12L USH2A SLC14A2 SDK1	1.85e-03	1434	172	18	EFO_0008354
Disease	oral microbiome measurement	ARHGAP40 ITPK1 KMT2C	1.89e-03	42	172	3	EFO_0801229
Disease	fibrinogen measurement, tissue plasminogen activator measurement	ATXN2L DIP2B CYP21A2	2.31e-03	45	172	3	EFO_0004623, EFO_0004791
Disease	fibrinogen measurement, plasminogen activator inhibitor 1 measurement	ATXN2L DIP2B CYP21A2	2.31e-03	45	172	3	EFO_0004623, EFO_0004792
Disease	interleukin 6 receptor subunit alpha measurement	CHRNB2 SHE	2.53e-03	13	172	2	EFO_0008187
Disease	frontal fibrosing alopecia	CACNA1A DHRS7B SDK1	2.78e-03	48	172	3	EFO_0009855
Disease	Malformations of Cortical Development	NDST1 DYNC1H1	2.94e-03	14	172	2	C1955869
Disease	revision of total hip arthroplasty	RIPK4 VWA7	2.94e-03	14	172	2	EFO_0020973
Disease	Cortical Dysplasia	NDST1 DYNC1H1	2.94e-03	14	172	2	C0431380
Disease	complement factor H-related protein 3 measurement	BEND4 FHIP2A USH2A SDK1 SBK2	3.19e-03	169	172	5	EFO_0600056
Disease	platelet crit	DIP2B DENND2A TTC28 CYP21A2 ITPK1 EPG5 DQX1 CYB5R3 NAV3 RP1 DOT1L MOV10 TRDMT1	3.97e-03	952	172	13	EFO_0007985
Disease	Ischemic stroke, fibrinogen measurement	ATXN2L DIP2B CYP21A2	4.09e-03	55	172	3	EFO_0004623, HP_0002140
Disease	factor XI measurement, fibrinogen measurement, tissue plasminogen activator measurement, factor VII measurement	ATXN2L DIP2B CYP21A2	4.30e-03	56	172	3	EFO_0004619, EFO_0004623, EFO_0004694, EFO_0004791
Disease	esophageal carcinoma, gastric carcinoma	SAMD5 EPG5	4.34e-03	17	172	2	EFO_0000178, EFO_0002916
Disease	Antibody Deficiency Syndrome	EPG5 CFD	4.34e-03	17	172	2	C0003257
Disease	autosomal dominant intellectual developmental disorder (is_implicated_in)	DIP2B ATP2B1	4.34e-03	17	172	2	DOID:0060307 (is_implicated_in)
Disease	coronary artery disease	TTC39B LINC01559 TTC41P CEL DEFB127 AHDC1 ITPK1 EPG5 CRACD EHBP1L1 OIT3 RP1 GPSM1 ATP2B1 SLC14A2	4.38e-03	1194	172	15	EFO_0001645
Disease	fibrinogen measurement, factor VII measurement	ATXN2L DIP2B CYP21A2	4.75e-03	58	172	3	EFO_0004619, EFO_0004623
Disease	protein-glutamine gamma-glutamyltransferase e measurement	RP1 SIGLEC1 NR0B2	5.22e-03	60	172	3	EFO_0020690
Disease	leukemia (implicated_via_orthology)	PKNOX2 DOT1L	5.41e-03	19	172	2	DOID:1240 (implicated_via_orthology)
Disease	age at first birth measurement	CACNA1A SOX11 DENND2A SDK1	5.42e-03	120	172	4	EFO_0009101
Disease	sexual dimorphism measurement	TTC39B ATXN2L DIP2B R3HCC1 PEX1 DDX27 BTN2A1 SLC4A1 BTN2A2 EHBP1L1 PLCB3 DOT1L HERC1 SBK2	5.49e-03	1106	172	14	EFO_0021796
Disease	waist-hip ratio	KNTC1 NDST1 PNPLA2 NUP85 TTC28 DTX1 RAPGEF3 GLI3 NAV3 PDZD8 PLCB3 PRKCSH DOT1L SLC14A2 PHLDB2	5.57e-03	1226	172	15	EFO_0004343
Disease	obsolete_red blood cell distribution width	DIP2B CEL TTC28 CYP21A2 APEH ZFAND4 SLC4A1 EPG5 EHBP1L1 CYB5R3 HELZ2 PRKCSH RP1 HERC1 GPSM1 TRDMT1	5.59e-03	1347	172	16	EFO_0005192

Protein segments in the cluster

Peptide	Gene	Start	Entry
KARRLDDYSLERVPP	CACNA1A	2131	O00555
LLRSERLYPELPSQL	EPG5	236	Q9HCE0
HRLARALNPAKLTPY	CARD10	36	Q9BWT7
QPKLSPDLTRLKERY	ARHGEF10L	201	Q9HCE6
AKGDLVRSILYPRPL	ATP13A5	376	Q4VNC0
KYRALTEPRTNLKLP	BTN3A3	441	O00478
ELLRRRYQSSPAKPD	SLC4A1	341	P02730
YRTLTEPRTNLKLPK	BTN3A1	441	O00481
RVPPSIYDTSLLKAL	FAM216B	21	Q8N7L0
ALAKRYERPTLVELP	BEND4	36	Q6ZU67
TLLRPRYLDLLVSSP	DPH2	166	Q9BQC3
ERPSVYLAARRQPLK	CYLC2	86	Q14093
LLPLEARTRDYASLP	DNMBP	446	Q6XZF7
LRASLLARYPPEKLF	DNMBP	1276	Q6XZF7
YRSTAERKLLPLLKP	ARHGEF15	266	O94989
LPNTLKPDSYRVTLR	ANPEP	76	P15144
LAAPDYTRLSPAKIV	DOT1L	766	Q8TEK3
VPRDSLLPLQDTAYR	AHDC1	1551	Q5TGY3
KQIAARLLPPLYSLV	CCR5	26	P51681
TDPRALTLAYKVPLA	CEL	281	P19835
YSNPLVAAKLLNIPR	ATP4B	241	P51164
RLKRLTSPLEYNLPS	AGTPBP1	1136	Q9UPW5
AFALPVLERLIYKPR	DDX27	271	Q96GQ7
LLLRKPYGRNKPLIS	ATP2B1	911	P20020
TETLLLRKPYGRNKP	ATP2B2	931	Q01814
LRKPYGRNKPLISRT	ATP2B2	936	Q01814
SLASREGKYIPLPQR	ATXN2L	341	Q8WWM7
SKVLLFPPLSSRLRY	R3HCC1	36	Q9Y3T6
KTRPLKAENPYLFLR	RBM12B	146	Q8IXT5
RSPTKSSLDYRRLPD	RBM14	626	Q96PK6
LESPDIKYPLRLIDR	CYB5R3	36	P00387
IYIRKDLRSPLIATP	NR2C2	211	P49116
YLRSLNKLPRQLPLE	RAD52	171	P43351
DQELADLPKTYLRRP	PTPRN2	106	Q92932
REPLPATLRITGYKS	NSUN2	71	Q08J23
SFLDIPRSRLVKYPL	NET1	306	Q7Z628
PRPQLYRSVSFKLLE	ARHGEF17	6	Q96PE2
SQPEPSKRLYDVLRA	CFD	86	P00746
ALAPYLPKEIRSSLV	RELCH	626	Q9P260
TRLYLDPGLREKLSL	PLOD3	196	O60568
TSALKQYLRSLPEPL	ARHGAP10	456	A1A4S6
LYFPRSLKEENRSLP	GDAP2	221	Q9NXN4
LPKSYIPSRLRKEIN	PALMD	146	Q9NP74
LRNLYRLSKALFPPE	PNPLA2	216	Q96AD5
VTPALNPLIYSLRNK	OR2AG2	281	A6NM03
PLPAIRTLLDRSKSY	ITPK1	96	Q13572
PSLLSLTPAQQYRLK	GLI3	916	P10071
RLVSSYRLKQPNVPF	KMT2C	4156	Q8NEZ4
LLSYEQRPLKRPRLG	MED12L	6	Q86YW9
PQKNIIRLSAEPRYL	MAN2A1	636	Q16706
KLSYRPRDSNELVPL	NCF2	391	P19878
LRSYRLSLQVEGKPP	HIPK4	366	Q8NE63
YPAVSLRLRDNNKPI	EDRF1	331	Q3B7T1
PSRDSLPLPVRSRKY	GPSM1	441	Q86YR5
IRDKYRSEALPTDLP	PRKCSH	276	P14314
AYRLLPSNALLLTAP	HMCN2	3806	Q8NDA2
RDLRLLKIAYQPPSE	FREM2	386	Q5SZK8
SVARPLLSYLLDLLP	HERC1	1076	Q15751
SSRVPYKDRARLPLL	CYP21A2	331	P08686
RLLYSNPTVKPIDLH	NUP85	311	Q9BW27
LTPLLNPLIYSLRNR	OR2T6	281	Q8NHC8
ITPSLNPLIYTLRNK	OR2W1	281	Q9Y3N9
TPILNPLIYTLRNKD	OR2Y1	281	Q8NGV0
EPYREALPTLKLRDS	OIT3	401	Q8WWZ8
PRVPYRDSKLTRLLQ	KIF22	316	Q14807
YLSKLRLEAPSPKAI	PDZD8	751	Q8NEN9
LDRNTLPKKGLRYTP	NAV3	1416	Q8IVL0
LPKEASPLRVIRSLY	DCAF10	511	Q5QP82
APLREALSQALKLYP	NRDE2	981	Q9H7Z3
IDTDDLPRKRLPQLY	DIP2B	1131	Q9P265
ALKYEALRAPVTQPR	EHBP1L1	896	Q8N3D4
LTGKRLSLPLDRYIL	NDST1	301	P52848
LISSLVPLAESKRYP	KNTC1	1216	P50748
PRDLQYSLSRSPLVL	EPHA10	341	Q5JZY3
VTPALNPLIYSLRNK	OR2AG1	281	Q9H205
IPSLNPLIYSLRNKE	OR5C1	286	Q8NGR4
RPKPATLALTLQDYV	DEFB127	71	Q9H1M4
LYALLSSSLKAVPRP	NR0B2	21	Q15466
RRLDLAYPLTVGSIP	DTX1	171	Q86Y01
TQPYPLAARSLALRV	DQX1	101	Q8TE96
VTPLLNPLVYSLRNK	OR10T2	281	Q8NGX3
NSSYPPLLRPERKAD	PLA2G4E	706	Q3MJ16
PLRPSQARLLIEKYE	PLCB3	266	Q01970
SPKILYRNPRFLRLA	BTBD18	6	B2RXH4
LSLPRLKPSEAGRYS	CSF1R	366	P07333
LESPILALPLYRSTR	C17orf99	226	Q6UX52
PPTRKLLAKNLAALY	HEATR5B	66	Q9P2D3
PELLQVKLYPDSRVR	DOCK7	526	Q96N67
TKPYLPSRALTRQQV	BRCA2	2881	P51587
SRLKQAPRYPSLARE	DENND2A	541	Q9ULE3
SLRAYPLLSVITRQP	BARX2	66	Q9UMQ3
PLSKLSRPYLVELLS	CRACD	976	Q6ZU35
RNPDYRSNKPIILRA	DSP	451	P15924
KETLRLYPVVPTNSR	CYP27A1	391	Q02318
LLDQRYARPPVLAKL	DDX11L8	861	A8MPP1
VPDLDRRKYLVPSDL	GABARAPL3	41	Q9BY60
KRRYPNSLPALILAA	CEP162	936	Q5TB80
YRAVSSPDRILPLKE	BTN2A1	431	Q7KYR7
RVPDERRYSLPLKSI	EDEM1	631	Q92611
SGRRKLAANYVPLLP	HAS1	491	Q92839
LRLIPSLRTYAEPLT	DYNC1H1	2756	Q14204
DLLPSLAVYLRTLAP	DHRS7B	291	Q6IAN0
YTKLLGRIRQPLLPH	FHIP2A	111	Q5W0V3
RKQYPISLVLAPTRE	DDX3Y	261	O15523
QARLYENLPPAALRK	HELZ2	1106	Q9BYK8
QYRALSSPERILPLK	BTN2A2	426	Q8WVV5
VLSRQLRALPSEDPY	CREB3	261	O43889
PLFKRSISLPYRDII	SAMD15	611	Q9P1V8
RAAILNLLPITSYPR	SDK1	206	Q7Z5N4
KQLPKPRTSLRGFLY	SBK2	91	P0C263
KYPELFANLPIRQRT	PEX1	861	O43933
KRAVYRHPLFPLLTL	PKNOX2	71	Q96KN3
PARYRKEQTLLKQLP	CAMSAP2	226	Q08AD1
KSLNFRINLPTPLAY	CNTD1	171	Q8N815
RNLLSTLPKYLFDLP	LRCH2	166	Q5VUJ6
TGEPLLTSPRYIAKR	LGSN	176	Q5TDP6
KYLLPARLPGISQRV	RP1	236	P56715
VTPLLNPLLYSLRNK	OR10Q1	286	Q8NGQ4
LRYSKEQRPTTLPIQ	RUSC2	681	Q8N2Y8
LRPSEYTKSVIDLRP	SYTL4	266	Q96C24
FLKRSLPALRQLTPD	TAF4	656	O00268
LLRRYNVAKVPASPT	SOX11	266	P35716
LPRSYTILRKDPEII	USH2A	1651	O75445
KLEAAYSPRNPLKRT	UTP20	2631	O75691
NPLLYLSRHTVKPRA	MRPL36	11	Q9P0J6
PRLNQLYERALKLLP	XAB2	51	Q9HCS7
TDVNQYLLPPKSLLR	TRDMT1	261	O14717
TRAYTLREKPQTLPS	PPP1R8	121	Q12972
APRSRELVSYPKLKL	SAMD5	116	Q5TGI4
RYTTSRRLDPIPQLK	SARAF	51	Q96BY9
RPRKLPDIFQSYDRL	LINC00869	201	P0C866
LPSSIYRLLAPSRDI	MOV10	571	Q9HCE1
LNRLPKLIYSLPADV	TMEM178A	236	Q8NBL3
SSAPPKVRRYQVLLS	NTHL1	121	P78549
PYKIILTARPFRLDL	GANAB	146	Q14697
LYSQVPDRLVLPATR	FOXE3	261	Q13461
LDRNTLPKKGLRYTP	NAV2	1506	Q8IVL1
LPKKGLRYTPTSQLR	NAV2	1511	Q8IVL1
PLRAATYRRPSVAKL	SSTR4	151	P31391
YRNLRKTVPPTDAKL	RNF32	206	Q9H0A6
SQNLYELLPRTSPLK	ST8SIA2	136	Q92186
SALYILTPLNPVRKI	SCN3A	106	Q9NY46
LPRLYRATENQLTPL	PHLDB2	256	Q86SQ0
KGYRQRLTVDTLPPL	ABCC12	66	Q96J65
AYLPPERIREKSRLF	RIPK4	186	P57078
LLDPSRYNKLIRPAT	CHRNB2	36	P17787
KTRNVPVRLLLYPKS	APEH	691	P13798
TARLKLRPPLNRAAY	CLCA4	686	Q14CN2
YLPLKRRADPDQLFS	LINC01559	36	Q495D7
PLLASSLPLAARYLQ	RNF31	36	Q96EP0
NHRVYRLALAKLSPP	RAPGEF3	796	O95398
VPFSIKPLLRRASAY	TOMM34	81	Q15785
SRYPRINKESLLPVA	UGP2	191	Q16851
RRYSASLPAPVKLIL	TTC39B	521	Q5VTQ0
LSVKRQYPSFLRTIP	TAS1R1	176	Q7RTX1
RFIRKLPTPLLTAEY	ARHGAP40	351	Q5TG30
LYTLTDVNIPPRRLD	TUBE1	306	Q9UJT0
NPRLVPYALLDERTK	RYR3	1016	Q15413
IESARQRPPKRKYLS	SUPT20H	16	Q8NEM7
PPRTAQGLRTLYKRL	FSBP	61	O95073
LEFRRLVLNYKPPSN	USP25	191	Q9UHP3
RINPTPTYKSILLLS	TTC41P	326	Q6P2S7
RERPHLAAKYLLQPV	TANGO6	406	Q9C0B7
ASLPALLLIRLPYTA	ATP6AP1	171	Q15904
SRPITLDVLYAPRNL	SIGLEC1	1161	Q9BZZ2
RKPRPKAAVYLNLSL	UNQ9370/PRO34162	121	Q6UXP9
FSQARPLTRYLPIRK	PHLDB1	1216	Q86UU1
LYPPRAKLVIQRHLS	TBC1D4	471	O60343
PPQRYILGIASSRTK	ZNF469	116	Q96JG9
SPERSLLLKYARTPT	TRIM14	256	Q14142
LLLKYARTPTLDPDT	TRIM14	261	Q14142
SSFAKPPLRALYDLL	TTC28	1386	Q96AY4
APLQRLTRYPLLLKN	PLEKHG7	436	Q6ZR37
DLQLRSTPFRYLLTP	PSMG2	131	Q969U7
IRLPSPYGSDRLVQL	ZBTB32	6	Q9Y2Y4
VLLKTADPRYELPSR	ZBED1	151	O96006
YRELSPHKNRLLSPL	ZFAND4	461	Q86XD8
RRSSKDLLGKPPQLY	SHE	276	Q5VZ18
TDLQSKKLRYIPIPR	VWA8	1456	A3KMH1
KKLRYIPIPRSESLS	VWA8	1461	A3KMH1
RLPLSKVTYPEANRI	SLC14A2	421	Q15849
RREILSPLRFEPYKA	VWA7	456	Q9Y334
YKSLPSLVPLRIAAL	TRRAP	1356	Q9Y4A5
ARLEPLYSPIRSKLS	TFIP11	561	Q9UBB9
TLIRARLQEKLSPPY	TRIM28	741	Q13263
KPSLAVNLADPYRSL	JUNB	36	P17275
PRDRAPLTYSLEKSV	MYOM3	526	Q5VTT5