Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	high voltage-gated calcium channel activity	CACNA1C CACNA1D CACNA1F CACNA1S	6.28e-08	14	58	4	GO:0008331
GeneOntologyMolecularFunction	voltage-gated calcium channel activity	CACNA1C CACNA1D CACNA1F CACNA1S	9.55e-06	46	58	4	GO:0005245
GeneOntologyMolecularFunction	voltage-gated calcium channel activity involved in cardiac muscle cell action potential	CACNA1C CACNA1D	8.25e-05	5	58	2	GO:0086007
GeneOntologyMolecularFunction	calcium channel activity	CACNA1C CACNA1D CACNA1F CACNA1S	5.38e-04	129	58	4	GO:0005262
GeneOntologyMolecularFunction	calcium ion transmembrane transporter activity	CACNA1C CACNA1D CACNA1F CACNA1S	9.71e-04	151	58	4	GO:0015085
GeneOntologyMolecularFunction	voltage-gated monoatomic cation channel activity	CACNA1C CACNA1D CACNA1F CACNA1S	9.95e-04	152	58	4	GO:0022843
GeneOntologyBiologicalProcess	calcium ion import across plasma membrane	CACNA1C CACNA1D CACNA1F CACNA1S	9.31e-06	48	57	4	GO:0098703
GeneOntologyBiologicalProcess	calcium ion import into cytosol	CACNA1C CACNA1D CACNA1F CACNA1S	9.31e-06	48	57	4	GO:1902656
GeneOntologyBiologicalProcess	positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel	CACNA1C CACNA1D	7.46e-05	5	57	2	GO:1904879
GeneOntologyBiologicalProcess	calcium ion import	CACNA1C CACNA1D CACNA1F CACNA1S	1.56e-04	98	57	4	GO:0070509
GeneOntologyBiologicalProcess	camera-type eye development	CACNA1C CACNA1F CACNA1S ZEB1 RP1 AQP5 MAP3K1	1.66e-04	426	57	7	GO:0043010
GeneOntologyCellularComponent	L-type voltage-gated calcium channel complex	CACNA1C CACNA1D CACNA1S	4.61e-06	12	59	3	GO:1990454
GeneOntologyCellularComponent	voltage-gated calcium channel complex	CACNA1C CACNA1D CACNA1F CACNA1S	8.55e-06	46	59	4	GO:0005891
GeneOntologyCellularComponent	calcium channel complex	CACNA1C CACNA1D CACNA1F CACNA1S	5.39e-05	73	59	4	GO:0034704
Domain	VDCC_L_a1su	CACNA1C CACNA1D CACNA1F CACNA1S	8.37e-11	4	58	4	IPR005446
Domain	VDCC_a1su_IQ	CACNA1C CACNA1D CACNA1F CACNA1S	2.91e-09	7	58	4	IPR014873
Domain	GPHH	CACNA1C CACNA1D CACNA1F CACNA1S	2.91e-09	7	58	4	PF16905
Domain	GPHH_dom	CACNA1C CACNA1D CACNA1F CACNA1S	2.91e-09	7	58	4	IPR031649
Domain	Ca_chan_IQ	CACNA1C CACNA1D CACNA1F CACNA1S	2.91e-09	7	58	4	SM01062
Domain	Ca_chan_IQ	CACNA1C CACNA1D CACNA1F CACNA1S	2.91e-09	7	58	4	PF08763
Domain	VDCCAlpha1	CACNA1C CACNA1D CACNA1F CACNA1S	1.73e-08	10	58	4	IPR002077
Domain	CAC1F_C	CACNA1C CACNA1D CACNA1F	2.84e-08	3	58	3	IPR031688
Domain	CAC1F_C	CACNA1C CACNA1D CACNA1F	2.84e-08	3	58	3	PF16885
Domain	Channel_four-helix_dom	CACNA1C CACNA1D CACNA1F CACNA1S TPTE2	8.96e-07	57	58	5	IPR027359
Domain	-	CACNA1C CACNA1D CACNA1F CACNA1S TPTE2	8.96e-07	57	58	5	1.20.120.350
Domain	Ion_trans_dom	CACNA1C CACNA1D CACNA1F CACNA1S TPTE2	2.75e-05	114	58	5	IPR005821
Domain	Ion_trans	CACNA1C CACNA1D CACNA1F CACNA1S TPTE2	2.75e-05	114	58	5	PF00520
Domain	DUF1518	NCOA3 NCOA1	2.84e-05	3	58	2	PF07469
Domain	DUF1518	NCOA3 NCOA1	2.84e-05	3	58	2	IPR010011
Domain	Nuc_rcpt_coact_Ncoa-typ	NCOA3 NCOA1	2.84e-05	3	58	2	IPR014920
Domain	SRC-1	NCOA3 NCOA1	2.84e-05	3	58	2	IPR014935
Domain	Src1_rcpt_coact	NCOA3 NCOA1	2.84e-05	3	58	2	IPR008955
Domain	Nuclear_rcpt_coactivator	NCOA3 NCOA1	2.84e-05	3	58	2	IPR017426
Domain	DUF1518	NCOA3 NCOA1	2.84e-05	3	58	2	SM01151
Domain	SRC-1	NCOA3 NCOA1	2.84e-05	3	58	2	PF08832
Domain	-	NCOA3 NCOA1	2.84e-05	3	58	2	4.10.630.10
Domain	Nuc_rec_co-act	NCOA3 NCOA1	2.84e-05	3	58	2	PF08815
Domain	Nuc_rcpt_coact	NCOA3 NCOA1	1.41e-04	6	58	2	IPR009110
Domain	PAS	NCOA3 NCOA1	2.72e-03	25	58	2	PF00989
Domain	PAS_fold	NCOA3 NCOA1	2.72e-03	25	58	2	IPR013767
Domain	Cys-rich_flank_reg_C	IGSF10 CHAD LRRC15	2.76e-03	90	58	3	IPR000483
Domain	LRRCT	IGSF10 CHAD LRRC15	2.76e-03	90	58	3	SM00082
Domain	LRRNT	IGSF10 CHAD LRRC15	3.51e-03	98	58	3	IPR000372
Domain	LRRNT	IGSF10 CHAD LRRC15	3.51e-03	98	58	3	SM00013
Domain	PAS	NCOA3 NCOA1	4.43e-03	32	58	2	SM00091
Domain	PAS	NCOA3 NCOA1	4.99e-03	34	58	2	IPR000014
Domain	PAS	NCOA3 NCOA1	4.99e-03	34	58	2	PS50112
Pathway	KEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_VGCC_CA2_APOPTOTIC_PATHWAY	CACNA1C CACNA1D CACNA1F CACNA1S	1.02e-09	6	42	4	M47762
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_VGCC_CA2_APOPTOTIC_PATHWAY_N01004	CACNA1C CACNA1D CACNA1F CACNA1S	6.67e-08	14	42	4	M47692
Pathway	KEGG_MEDICUS_REFERENCE_VGCC_CA2_APOPTOTIC_PATHWAY	CACNA1C CACNA1D CACNA1F CACNA1S	5.78e-07	23	42	4	M47666
Pathway	KEGG_MEDICUS_REFERENCE_CA2_ENTRY_VOLTAGE_GATED_CA2_CHANNEL	CACNA1C CACNA1D CACNA1F CACNA1S	8.23e-07	25	42	4	M47948
Pathway	KEGG_GNRH_SIGNALING_PATHWAY	CACNA1C CACNA1D CACNA1F CACNA1S MAP3K1	1.18e-05	101	42	5	M1979
Pathway	KEGG_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY_ARVC	CACNA1C CACNA1D CACNA1F CACNA1S	6.73e-05	74	42	4	M16376
Pathway	WP_ALZHEIMERS_DISEASE	CACNA1C CACNA1D CACNA1F CACNA1S	6.73e-05	74	42	4	MM15962
Pathway	WP_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY	CACNA1C CACNA1D CACNA1F CACNA1S	6.73e-05	74	42	4	M39462
Pathway	KEGG_MEDICUS_VARIANT_ESR1_POSITIVE_TO_NUCLEAR_INITIATED_ESTROGEN_SIGNALING_PATHWAY	NCOA3 NCOA1	8.62e-05	5	42	2	M48983
Pathway	KEGG_CARDIAC_MUSCLE_CONTRACTION	CACNA1C CACNA1D CACNA1F CACNA1S	8.70e-05	79	42	4	M17673
Pathway	KEGG_HYPERTROPHIC_CARDIOMYOPATHY_HCM	CACNA1C CACNA1D CACNA1F CACNA1S	1.05e-04	83	42	4	M8728
Pathway	KEGG_DILATED_CARDIOMYOPATHY	CACNA1C CACNA1D CACNA1F CACNA1S	1.44e-04	90	42	4	M835
Pathway	KEGG_CALCIUM_SIGNALING_PATHWAY	CACNA1C CACNA1D CACNA1F CACNA1S HTR2C	1.77e-04	178	42	5	M2890
Pathway	REACTOME_NCAM1_INTERACTIONS	CACNA1C CACNA1D CACNA1S	2.60e-04	42	42	3	M7169
Pathway	KEGG_VASCULAR_SMOOTH_MUSCLE_CONTRACTION	CACNA1C CACNA1D CACNA1F CACNA1S	3.70e-04	115	42	4	M9387
Pathway	KEGG_MEDICUS_REFERENCE_CA2_CAM_VGCC_RYR_SIGNALING_PATHWAY	CACNA1C CACNA1S	4.69e-04	11	42	2	M47958
Pathway	KEGG_MEDICUS_REFERENCE_NUCLEAR_INITIATED_ESTROGEN_SIGNALING_PATHWAY	NCOA3 NCOA1	4.69e-04	11	42	2	M47503
Pathway	WP_MAPK_SIGNALING	CACNA1C CACNA1D CACNA1F CACNA1S MAP3K1	7.80e-04	246	42	5	M39597
Pathway	REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH	CACNA1C CACNA1D CACNA1S	8.62e-04	63	42	3	M11187
Pathway	PID_ERB_GENOMIC_PATHWAY	NCOA3 NCOA1	8.88e-04	15	42	2	M119
Pathway	PID_ERA_GENOMIC_PATHWAY	NCOA3 NCOA1 STAT5A	9.03e-04	64	42	3	M200
Pathway	KEGG_MAPK_SIGNALING_PATHWAY	CACNA1C CACNA1D CACNA1F CACNA1S MAP3K1	1.13e-03	267	42	5	M10792
Pathway	REACTOME_REGULATION_OF_LIPID_METABOLISM_BY_PPARALPHA	NCOA1 CHD9	1.29e-03	18	42	2	MM15034
Pathway	REACTOME_RORA_ACTIVATES_GENE_EXPRESSION	NCOA1 CHD9	1.29e-03	18	42	2	M26942
Pathway	KEGG_ALZHEIMERS_DISEASE	CACNA1C CACNA1D CACNA1F CACNA1S	1.46e-03	166	42	4	M16024
Pubmed	Beta-adrenergic-regulated phosphorylation of the skeletal muscle Ca(V)1.1 channel in the fight-or-flight response.	CACNA1C CACNA1D CACNA1F CACNA1S	7.47e-12	4	59	4	20937870
Pubmed	Enhanced expression of L-type Cav1.3 calcium channels in murine embryonic hearts from Cav1.2-deficient mice.	CACNA1C CACNA1D CACNA1F CACNA1S	2.60e-10	7	59	4	12900400
Pubmed	Angiotensin II suppresses long-term depression in the lateral amygdala of mice via L-type calcium channels.	CACNA1C CACNA1D CACNA1S	4.64e-09	3	59	3	17289261
Pubmed	Impairment of hippocampal gamma-frequency oscillations in vitro in mice overexpressing human amyloid precursor protein (APP).	CACNA1C CACNA1D CACNA1S	4.64e-09	3	59	3	17767505
Pubmed	Molecular diversity of L-type calcium channels. Evidence for alternative splicing of the transcripts of three non-allelic genes.	CACNA1C CACNA1D CACNA1S	4.64e-09	3	59	3	2173707
Pubmed	Voltage-activated calcium channel expression profiles in mouse brain and cultured hippocampal neurons.	CACNA1C CACNA1D CACNA1F CACNA1S	1.01e-08	15	59	4	20188150
Pubmed	Differential neuronal targeting of a new and two known calcium channel β4 subunit splice variants correlates with their regulation of gene expression.	CACNA1C CACNA1D CACNA1F CACNA1S	1.01e-08	15	59	4	24453333
Pubmed	Evolutionary insights into T-type Ca2+ channel structure, function, and ion selectivity from the Trichoplax adhaerens homologue.	CACNA1D CACNA1F CACNA1S	2.58e-07	8	59	3	28330839
Pubmed	International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels.	CACNA1C CACNA1F CACNA1S	3.87e-07	9	59	3	16382099
Pubmed	NCAM induces CaMKIIalpha-mediated RPTPalpha phosphorylation to enhance its catalytic activity and neurite outgrowth.	CACNA1C CACNA1D CACNA1F	7.58e-07	11	59	3	18809727
Pubmed	Temporal expression of calcium channel subunits in satellite cells and bone marrow mesenchymal cells.	CACNA1C CACNA1S	2.83e-06	2	59	2	25277766
Pubmed	Deletion of the L-type calcium channel Ca(V) 1.3 but not Ca(V) 1.2 results in a diminished sAHP in mouse CA1 pyramidal neurons.	CACNA1C CACNA1D	2.83e-06	2	59	2	20014384
Pubmed	Role of putative voltage-sensor countercharge D4 in regulating gating properties of CaV1.2 and CaV1.3 calcium channels.	CACNA1C CACNA1D	2.83e-06	2	59	2	30001160
Pubmed	Rescue and worsening of congenital heart block-associated electrocardiographic abnormalities in two transgenic mice.	CACNA1C CACNA1D	2.83e-06	2	59	2	21352396
Pubmed	A single nucleotide deletion in the skeletal muscle-specific calcium channel transcript of muscular dysgenesis (mdg) mice.	CACNA1C CACNA1S	2.83e-06	2	59	2	1281468
Pubmed	Identification of a PEAK1/ZEB1 signaling axis during TGFβ/fibronectin-induced EMT in breast cancer.	ZEB1 PEAK1	2.83e-06	2	59	2	26297948
Pubmed	The coactivator SRC-1 is an essential coordinator of hepatic glucose production.	NCOA3 NCOA1	2.83e-06	2	59	2	21109193
Pubmed	Different roles attributed to Cav1 channel subtypes in spontaneous action potential firing and fine tuning of exocytosis in mouse chromaffin cells.	CACNA1C CACNA1D	2.83e-06	2	59	2	21054386
Pubmed	Molecular nature of anomalous L-type calcium channels in mouse cerebellar granule cells.	CACNA1C CACNA1D	2.83e-06	2	59	2	17409250
Pubmed	Steroid receptor coactivator (SRC)-1 and SRC-3 differentially modulate tissue-specific activation functions of the progesterone receptor.	NCOA3 NCOA1	2.83e-06	2	59	2	16141356
Pubmed	Neuronal L-type calcium channels open quickly and are inhibited slowly.	CACNA1C CACNA1D	2.83e-06	2	59	2	16267232
Pubmed	Immunohistochemical localization of steroid receptor coactivators in chondrosarcoma: an in vivo tissue microarray study.	NCOA3 NCOA1	2.83e-06	2	59	2	24875297
Pubmed	The role of L-type voltage-gated calcium channels Cav1.2 and Cav1.3 in normal and pathological brain function.	CACNA1C CACNA1D	2.83e-06	2	59	2	24996399
Pubmed	Voltage-Gated Cav1 Channels in Disorders of Vision and Hearing.	CACNA1D CACNA1F	2.83e-06	2	59	2	25966695
Pubmed	An improved targeted cAMP sensor to study the regulation of adenylyl cyclase 8 by Ca2+ entry through voltage-gated channels.	CACNA1C CACNA1D	2.83e-06	2	59	2	24086669
Pubmed	Genetic, cellular, and functional evidence for Ca2+ inflow through Cav1.2 and Cav1.3 channels in murine spiral ganglion neurons.	CACNA1C CACNA1D	2.83e-06	2	59	2	24849370
Pubmed	Differential zinc permeation and blockade of L-type Ca2+ channel isoforms Cav1.2 and Cav1.3.	CACNA1C CACNA1D	2.83e-06	2	59	2	26049024
Pubmed	Endogenous cardiac Ca2+ channels do not overcome the E-C coupling defect in immortalized dysgenic muscle cells: evidence for a missing link.	CACNA1C CACNA1S	2.83e-06	2	59	2	7635187
Pubmed	Divide and conquer: an L-type voltage-gated calcium channel subtype finds a role in conditioned fear.	CACNA1C CACNA1D	2.83e-06	2	59	2	17015854
Pubmed	Genetic polymorphisms of L-type calcium channel alpha1C and alpha1D subunit genes are associated with sensitivity to the antihypertensive effects of L-type dihydropyridine calcium-channel blockers.	CACNA1C CACNA1D	2.83e-06	2	59	2	19225208
Pubmed	Ca1.2 and CaV1.3 neuronal L-type calcium channels: differential targeting and signaling to pCREB.	CACNA1C CACNA1D	2.83e-06	2	59	2	16706838
Pubmed	[The expression of genes encoding the voltage-dependent L-type Ca2+ channels in proliferating and differentiating C2C12 myoblasts of mice].	CACNA1D CACNA1S	2.83e-06	2	59	2	21789999
Pubmed	Temperature-sensitive Cav1.2 calcium channels support intrinsic firing of pyramidal neurons and provide a target for the treatment of febrile seizures.	CACNA1C CACNA1D	2.83e-06	2	59	2	23761887
Pubmed	Non-voltage-gated L-type Ca2+ channels in human T cells: pharmacology and molecular characterization of the major alpha pore-forming and auxiliary beta-subunits.	CACNA1C CACNA1D	2.83e-06	2	59	2	14981074
Pubmed	Critical roles of the p160 transcriptional coactivators p/CIP and SRC-1 in energy balance.	NCOA3 NCOA1	2.83e-06	2	59	2	16459312
Pubmed	CaV1.2 and CaV1.3 channel hyperactivation in mouse islet β cells exposed to type 1 diabetic serum.	CACNA1C CACNA1D	2.83e-06	2	59	2	25292336
Pubmed	Ca(v)1.3 channels produce persistent calcium sparklets, but Ca(v)1.2 channels are responsible for sparklets in mouse arterial smooth muscle.	CACNA1C CACNA1D	2.83e-06	2	59	2	17526649
Pubmed	Mechanisms Responsible for ω-Pore Currents in Cav Calcium Channel Voltage-Sensing Domains.	CACNA1D CACNA1S	2.83e-06	2	59	2	28978442
Pubmed	Ligand-activated signal transduction in the 2-cell embryo.	CACNA1C CACNA1D	2.83e-06	2	59	2	12606379
Pubmed	Pyrimidine-2,4,6-triones are a new class of voltage-gated L-type Ca2+ channel activators.	CACNA1C CACNA1D	2.83e-06	2	59	2	24941892
Pubmed	Cav1.2 and Cav1.3 L-type calcium channels regulate dopaminergic firing activity in the mouse ventral tegmental area.	CACNA1C CACNA1D	2.83e-06	2	59	2	24848473
Pubmed	Equal sensitivity of Cav1.2 and Cav1.3 channels to the opposing modulations of PKA and PKG in mouse chromaffin cells.	CACNA1C CACNA1D	2.83e-06	2	59	2	22826131
Pubmed	C-terminal modulator controls Ca2+-dependent gating of Ca(v)1.4 L-type Ca2+ channels.	CACNA1D CACNA1F	2.83e-06	2	59	2	16921373
Pubmed	Transcriptional regulation of L-type calcium channel subtypes Cav1.2 and Cav1.3 by nicotine and their potential role in nicotine sensitization.	CACNA1C CACNA1D	2.83e-06	2	59	2	24470632
Pubmed	Cav1.2 and Cav1.3 L-type calcium channels operate in a similar voltage range but show different coupling to Ca(2+)-dependent conductances in hippocampal neurons.	CACNA1C CACNA1D	2.83e-06	2	59	2	24760982
Pubmed	Sorcin associates with the pore-forming subunit of voltage-dependent L-type Ca2+ channels.	CACNA1C CACNA1S	8.48e-06	3	59	2	9668070
Pubmed	The intracellular II-III loops of Cav1.2 and Cav1.3 uncouple L-type voltage-gated Ca2+ channels from glucagon-like peptide-1 potentiation of insulin secretion in INS-1 cells via displacement from lipid rafts.	CACNA1C CACNA1D	8.48e-06	3	59	2	19351867
Pubmed	NCoA-1/SRC-1 is an essential coactivator of STAT5 that binds to the FDL motif in the alpha-helical region of the STAT5 transactivation domain.	NCOA1 STAT5A	8.48e-06	3	59	2	12954634
Pubmed	Truncation of murine CaV1.2 at Asp-1904 results in heart failure after birth.	CACNA1C CACNA1D	8.48e-06	3	59	2	21832054
Pubmed	The transcriptional coregulators TIF2 and SRC-1 regulate energy homeostasis by modulating mitochondrial respiration in skeletal muscles.	NCOA3 NCOA1	8.48e-06	3	59	2	21035760
Pubmed	Distinctive functions of p160 steroid receptor coactivators in proliferation of an estrogen-independent, tamoxifen-resistant breast cancer cell line.	NCOA3 NCOA1	8.48e-06	3	59	2	21059860
Pubmed	Potent inhibition of L-type Ca2+ currents by a Rad variant associated with congestive heart failure.	CACNA1C CACNA1D	8.48e-06	3	59	2	23973784
Pubmed	Ligand-independent recruitment of steroid receptor coactivators to estrogen receptor by cyclin D1.	NCOA3 NCOA1	8.48e-06	3	59	2	9832502
Pubmed	Absence of the steroid receptor coactivator-3 induces B-cell lymphoma.	NCOA3 NCOA1	8.48e-06	3	59	2	16675958
Pubmed	Partial hormone resistance in mice with disruption of the steroid receptor coactivator-1 (SRC-1) gene.	NCOA3 NCOA1	8.48e-06	3	59	2	9506940
Pubmed	Steroid receptor coactivators present a unique opportunity for drug development in hormone-dependent cancers.	NCOA3 NCOA1	8.48e-06	3	59	2	28390937
Pubmed	MicroRNA-1976 regulates degeneration of the sinoatrial node by targeting Cav1.2 and Cav1.3 ion channels.	CACNA1C CACNA1D	8.48e-06	3	59	2	31302118
Pubmed	Distinct localization and modulation of Cav1.2 and Cav1.3 L-type Ca2+ channels in mouse sinoatrial node.	CACNA1C CACNA1D	8.48e-06	3	59	2	23045342
Pubmed	A mutant form of ERα associated with estrogen insensitivity affects the coupling between ligand binding and coactivator recruitment.	NCOA3 NCOA1	8.48e-06	3	59	2	32963012
Pubmed	Research resource: loss of the steroid receptor coactivators confers neurobehavioral consequences.	NCOA3 NCOA1	8.48e-06	3	59	2	23927929
Pubmed	Triad proteins and intracellular Ca2+ transients during development of human skeletal muscle cells in aneural and innervated cultures.	CACNA1C CACNA1S	8.48e-06	3	59	2	11206130
Pubmed	Cav1.3 channels control D2-autoreceptor responses via NCS-1 in substantia nigra dopamine neurons.	CACNA1C CACNA1D	8.48e-06	3	59	2	24934288
Pubmed	mRNA for cardiac calcium channel is expressed during development of skeletal muscle.	CACNA1C CACNA1S	8.48e-06	3	59	2	8381753
Pubmed	Expression and significance of androgen receptor coactivators in urothelial carcinoma of the bladder.	NCOA3 NCOA1	8.48e-06	3	59	2	18845648
Pubmed	The function of TIF2/GRIP1 in mouse reproduction is distinct from those of SRC-1 and p/CIP.	NCOA3 NCOA1	8.48e-06	3	59	2	12138202
Pubmed	G protein-gated IKACh channels as therapeutic targets for treatment of sick sinus syndrome and heart block.	CACNA1C CACNA1D	8.48e-06	3	59	2	26831068
Pubmed	Structure and chromosomal locations of mouse steroid receptor coactivator gene family.	NCOA3 NCOA1	8.48e-06	3	59	2	10501088
Pubmed	Estradiol increases cell growth in human astrocytoma cell lines through ERα activation and its interaction with SRC-1 and SRC-3 coactivators.	NCOA3 NCOA1	8.48e-06	3	59	2	22142990
Pubmed	The transcriptional coactivators p/CIP and SRC-1 control insulin resistance through IRS1 in obesity models.	NCOA3 NCOA1	8.48e-06	3	59	2	22859932
Pubmed	The steroid receptor coactivator-1 regulates twist expression and promotes breast cancer metastasis.	NCOA3 NCOA1	8.48e-06	3	59	2	19383905
Pubmed	Truncation of murine CaV1.2 at Asp 1904 increases CaV1.3 expression in embryonic atrial cardiomyocytes.	CACNA1C CACNA1D	8.48e-06	3	59	2	23338940
Pubmed	The genomic analysis of the impact of steroid receptor coactivators ablation on hepatic metabolism.	NCOA3 NCOA1	8.48e-06	3	59	2	16423883
Pubmed	Genetic dissection of horizontal cell inhibitory signaling in mice in complete darkness in vivo.	CACNA1D CACNA1F	8.48e-06	3	59	2	26024096
Pubmed	miR-137 Targets p160 Steroid Receptor Coactivators SRC1, SRC2, and SRC3 and Inhibits Cell Proliferation.	NCOA3 NCOA1	1.69e-05	4	59	2	26066330
Pubmed	Steroid receptor coactivator-1 and its family members differentially regulate transactivation by the tumor suppressor protein p53.	NCOA3 NCOA1	1.69e-05	4	59	2	10551785
Pubmed	STAT5 interaction with the T cell receptor complex and stimulation of T cell proliferation.	CD247 STAT5A	1.69e-05	4	59	2	9880255
Pubmed	P160/SRC/NCoA coactivators form complexes via specific interaction of their PAS-B domain with the CID/AD1 domain.	NCOA3 NCOA1	1.69e-05	4	59	2	18267973
Pubmed	Selective recruitment of p160 coactivators on glucocorticoid-regulated promoters in Schwann cells.	NCOA3 NCOA1	1.69e-05	4	59	2	15331759
Pubmed	Molecular coupling of a Ca2+-activated K+ channel to L-type Ca2+ channels via alpha-actinin2.	CACNA1C CACNA1D	1.69e-05	4	59	2	17110593
Pubmed	Unique roles of p160 coactivators for regulation of breast cancer cell proliferation and estrogen receptor-alpha transcriptional activity.	NCOA3 NCOA1	1.69e-05	4	59	2	19095746
Pubmed	Ablation of steroid receptor coactivator-3 resembles the human CACT metabolic myopathy.	NCOA3 NCOA1	1.69e-05	4	59	2	22560224
Pubmed	Characterization of a Steroid Receptor Coactivator Small Molecule Stimulator that Overstimulates Cancer Cells and Leads to Cell Stress and Death.	NCOA3 NCOA1	1.69e-05	4	59	2	26267537
Pubmed	Mutation of a lysine residue in a homeodomain generates dominant negative thyroid transcription factor 1.	NCOA3 NCOA1	1.69e-05	4	59	2	15449938
Pubmed	Nuclear receptor coregulator SNP discovery and impact on breast cancer risk.	NCOA3 NCOA1	1.69e-05	4	59	2	20003447
Pubmed	Nuclear hormone receptor coregulator GRIP1 suppresses, whereas SRC1A and p/CIP coactivate, by domain-specific binding of MyoD.	NCOA3 NCOA1	1.69e-05	4	59	2	15563453
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	CACNA1C SUPT20H CHD9 RP1 SPATA31A6 STAT5A SCAF4	2.09e-05	497	59	7	36774506
Pubmed	Transcription activation by the orphan nuclear receptor, chicken ovalbumin upstream promoter-transcription factor I (COUP-TFI). Definition of the domain involved in the glucocorticoid response of the phosphoenolpyruvate carboxykinase gene.	NCOA3 NCOA1	2.82e-05	5	59	2	10652338
Pubmed	Redundant enhancement of mouse constitutive androstane receptor transactivation by p160 coactivator family members.	NCOA3 NCOA1	2.82e-05	5	59	2	17950690
Pubmed	SIP, a novel ankyrin repeat containing protein, sequesters steroid receptor coactivators in the cytoplasm.	NCOA3 NCOA1	2.82e-05	5	59	2	17476305
Pubmed	Ontogeny of steroid receptor coactivators in the hippocampus and their role in regulating postnatal HPA axis function.	NCOA3 NCOA1	2.82e-05	5	59	2	17854779
Pubmed	Dual role of the arginine methyltransferase CARM1 in the regulation of c-Fos target genes.	NCOA3 NCOA1	2.82e-05	5	59	2	18511550
Pubmed	Ligand-independent interactions of p160/steroid receptor coactivators and CREB-binding protein (CBP) with estrogen receptor-alpha: regulation by phosphorylation sites in the A/B region depends on other receptor domains.	NCOA3 NCOA1	2.82e-05	5	59	2	12714702
Pubmed	Transcription factor-specific requirements for coactivators and their acetyltransferase functions.	NCOA3 NCOA1	2.82e-05	5	59	2	9445475
Pubmed	Regulation of transcription by a protein methyltransferase.	NCOA3 NCOA1	2.82e-05	5	59	2	10381882
Pubmed	Antinociceptive effect of different types of calcium channel inhibitors and the distribution of various calcium channel alpha 1 subunits in the dorsal horn of spinal cord in mice.	CACNA1C CACNA1D	2.82e-05	5	59	2	15451373
Pubmed	SRC-1 null mice exhibit moderate motor dysfunction and delayed development of cerebellar Purkinje cells.	NCOA3 NCOA1	2.82e-05	5	59	2	12514218
Pubmed	Ligands specify coactivator nuclear receptor (NR) box affinity for estrogen receptor subtypes.	NCOA3 NCOA1	2.82e-05	5	59	2	11376110
Pubmed	Identification of COUP-TFII orphan nuclear receptor as a retinoic acid-activated receptor.	NCOA3 NCOA1	2.82e-05	5	59	2	18798693
Pubmed	Isoform-selective interactions between estrogen receptors and steroid receptor coactivators promoted by estradiol and ErbB-2 signaling in living cells.	NCOA3 NCOA1	2.82e-05	5	59	2	12554772
Pubmed	Kv2.1 mediates spatial and functional coupling of L-type calcium channels and ryanodine receptors in mammalian neurons.	CACNA1C CACNA1D	2.82e-05	5	59	2	31663850
GeneFamily	Calcium voltage-gated channel subunits	CACNA1C CACNA1D CACNA1F CACNA1S	3.99e-07	26	43	4	253
GeneFamily	Zinc fingers ZZ-type\|Lysine acetyltransferases	NCOA3 NCOA1	7.35e-04	17	43	2	486
Coexpression	GSE9006_TYPE_1_VS_TYPE_2_DIABETES_PBMC_AT_DX_DN	SPATS2L NCOA1 CHD9 PCNX1 SCAF4	7.93e-05	199	58	5	M5799
Coexpression	GSE14308_TH2_VS_NAIVE_CD4_TCELL_DN	NCOA3 CD247 NCOA1 RNF145 STAT5A	8.12e-05	200	58	5	M3365
Coexpression	GSE17721_POLYIC_VS_GARDIQUIMOD_16H_BMDC_UP	NCOA3 NCOA1 BOD1L1 SCAF4 C19orf25	8.12e-05	200	58	5	M4031
Coexpression	GSE14769_UNSTIM_VS_20MIN_LPS_BMDM_DN	CIZ1 PCNX1 RP1 PEAK1 NEDD1	8.12e-05	200	58	5	M3491
Coexpression	GSE32986_UNSTIM_VS_CURDLAN_HIGHDOSE_STIM_DC_UP	ZEB1 ORC3 CEP295 ODF2 NEDD1	8.12e-05	200	58	5	M8614
Coexpression	GSE17721_LPS_VS_PAM3CSK4_16H_BMDC_UP	PITPNM1 CD247 SUPT20H RBM43 PHC1	8.12e-05	200	58	5	M3927
Coexpression	GSE40273_GATA1_KO_VS_WT_TREG_DN	NCOA3 ZEB1 NCOA1 TEP1 MAP3K1	8.12e-05	200	58	5	M9133
ToppCell	IPF-Epithelial-Club\|Epithelial / Disease state, Lineage and Cell class	PLEKHG1 MGP ROS1 RNF145 AQP5 GGT5	2.08e-07	192	59	6	356e7a820b744a0ac87352a8d0e6e8d9fa9ed7d2
ToppCell	368C-Myeloid-Dendritic-cDC_activated\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	PLEKHG1 ZEB1 SCEL TMEM178B LONRF2	2.58e-06	164	59	5	67c636a2cc32e56c6186dc7e779cc19af04639d2
ToppCell	368C-Myeloid-Dendritic-cDC_activated\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	PLEKHG1 ZEB1 SCEL TMEM178B LONRF2	2.66e-06	165	59	5	9d2bdc42c13c8c2a68889bec8612a1ce56f659fa
ToppCell	COVID-19-Fibroblasts-Other_FB\|COVID-19 / group, cell type (main and fine annotations)	CACNA1C CACNA1D ZEB1 MGP HPSE2	5.72e-06	193	59	5	e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PLEKHG1 NCOA3 CHD9 BOD1L1 MAP3K1	5.87e-06	194	59	5	d852aebf7a763b9a776c4570711f0c759f591910
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PLEKHG1 NCOA3 CHD9 BOD1L1 MAP3K1	6.01e-06	195	59	5	481989d2e5bd2582da3d86b0155c4d6615317067
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PLEKHG1 NCOA3 CHD9 BOD1L1 MAP3K1	6.01e-06	195	59	5	6108a27523d1b93a7fbe35cb95704a5ad9071e3c
ToppCell	facs-Brain_Myeloid-Hippocampus\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGP MED12L CHD9 PEAK1 GGT5	6.01e-06	195	59	5	a1478021a3ed0e779716393124ca2a7770c433b7
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CACNA1C CACNA1D ZEB1 MGP HPSE2	6.32e-06	197	59	5	44673c38384453207871d3fd8e8ba9093cc06bc5
ToppCell	Biopsy_Control_(H.)-Epithelial-SCGB3A2+\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	CACNA1S MGP ROS1 RNF145 AQP5	6.48e-06	198	59	5	1fe51f4beca0eef4ff117e6edaa646e35c0f9629
ToppCell	TCGA-Peripheral_Nervous_System-Primary_Tumor-Paraganglioma-Paraganglioma-3\|TCGA-Peripheral_Nervous_System / Sample_Type by Project: Shred V9	CACNA1D CHD9 RBM43 PHC1	3.10e-05	135	59	4	ac20133d4a36f48338b45bffb13e842cb66f83ad
ToppCell	remission-multiplets\|World / disease stage, cell group and cell class	IGSF10 CACNA1F MED12L KIAA2012	3.78e-05	142	59	4	286d01b4f95e9c0b38b91958f925f3797dffd596
ToppCell	343B-Epithelial_cells-Epithelial-E_(AT2)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	CACNA1F USP13 SCEL AQP5	4.10e-05	145	59	4	80684ec249fa445c1b35f94608a4a6824d53f2d9
ToppCell	343B-Epithelial_cells-Epithelial-E_(AT2)\|343B / Donor, Lineage, Cell class and subclass (all cells)	CACNA1F USP13 SCEL AQP5	4.10e-05	145	59	4	cb534333fba44b241b14fb0d7b74e843f4e7f9f8
ToppCell	Club_cells-SSc-ILD_02\|World / lung cells shred on cell class, cell subclass, sample id	IGSF10 MGP DNAJC22 AQP5	4.33e-05	147	59	4	9211242a8e40d50414d310940616eccce299a7f8
ToppCell	remission-multiplets\|remission / disease stage, cell group and cell class	IGSF10 CACNA1F MED12L KIAA2012	4.56e-05	149	59	4	e9974260a5f2999b363f306cae005698c912893a
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	KIF20A RP1 SCEL TMEM178B	5.06e-05	153	59	4	499670e716fc85ce76630fc813cec86f8419f2a1
ToppCell	Leuk-UTI-Myeloid-tDC\|Leuk-UTI / Disease, Lineage and Cell Type	IGSF10 ZEB1 ZNF789 MED12L	6.17e-05	161	59	4	51b9f60986ed2e8e2297d31c80462c3ab65a2e5e
ToppCell	wk_15-18-Epithelial-Airway_epithelial_progenitor-epi-prox-progenitor_intermediate_\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	CACNA1F MED12L RP1 AQP5	6.78e-05	165	59	4	f6887c64af0f26e33316bc5587487e24d76ece2a
ToppCell	PND01-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PITPNM1 KIF20A N4BP2L1 ODF2	7.27e-05	168	59	4	52fd65024af8683db11d931f7563cbe8eb815d1c
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CACNA1D USP13 SPATS2L MGP	7.61e-05	170	59	4	8465c3069bbc08705d070927e712b6bc85ac7c5b
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Chat_Htr1f\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	PLEKHG1 HTR2C AQP5 MAP3K1	7.79e-05	171	59	4	f9ae7964a3740f559431125c17c660549798cccc
ToppCell	facs-Lung-EPCAM-18m-Myeloid-Ccr7+_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	N4BP2L1 CACNA1S DNAJC22 STAT5A	7.97e-05	172	59	4	c5caae0b21e35a2d5dcd898fbfa1ef33f92c019f
ToppCell	facs-Lung-EPCAM-18m-Myeloid-dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	N4BP2L1 CACNA1S DNAJC22 STAT5A	7.97e-05	172	59	4	7c085c02b59e24e2a2cd393b5e692f9fb19257fe
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1C CACNA1D PCNX1 GABBR2	8.33e-05	174	59	4	f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Chat_Htr1f\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	PLEKHG1 HTR2C AQP5 MAP3K1	8.33e-05	174	59	4	a5f2a4e3b25e6084bd7003a53da86a44f6fcf294
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1C CACNA1D PCNX1 GABBR2	9.10e-05	178	59	4	fcbbcc44271515de1969b4732b6441c012693d5f
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IGSF10 CACNA1C CACNA1D MGP	9.50e-05	180	59	4	9b1de1b4711adbf9a423f4d2d08f3f4c78f1f8f4
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IGSF10 CACNA1C CACNA1D MGP	9.70e-05	181	59	4	9e7d0f1afb8d9bc5a209ddb5314df3a25a0274d9
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1F SYT9 SCEL AQP5	9.70e-05	181	59	4	b45b11428d13950369347e051d4d517efb2bd4fd
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PLEKHG1 PEAK1 LRRC15 GGT5	9.70e-05	181	59	4	e898ecb8d8f2eb2204225b7b0d665cadcd241139
ToppCell	facs-Lung-nan-3m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGSF10 CACNA1D MGP PEAK1	9.91e-05	182	59	4	c557de6ccd327c46e0a5423cd9936d78e0abae5f
ToppCell	droplet-Marrow-nan-3m-Hematologic-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD247 CHD9 BOD1L1 PEAK1	9.91e-05	182	59	4	e78ba2c5cae480c16a596ce7c3bf2d480becacf4
ToppCell	droplet-Marrow-nan-3m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD247 CHD9 BOD1L1 PEAK1	9.91e-05	182	59	4	1710eab3037a87609d21838be2d2d29c3bc36651
ToppCell	facs-Lung-nan-3m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGSF10 CACNA1D MGP PEAK1	9.91e-05	182	59	4	dbe4b2557cf19e0682ed446f8397d3a1153642f0
ToppCell	5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SUPT20H HPSE2 PHC1 LRRC15	1.01e-04	183	59	4	5377b4fbd8fdfe68933b4c0965aa9525f7f31591
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CD247 ZEB1 SUPT20H PCNX1	1.03e-04	184	59	4	bd786db4dc4edae6d5cfc0b69901983dea19f729
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PLEKHG1 RP1 RNF145 AQP5	1.06e-04	185	59	4	98b8ee42b89d97e4c9db01740e0c193503c68f2c
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell-D231\|Adult / Lineage, Cell type, age group and donor	CACNA1C CACNA1D ZEB1 MGP	1.06e-04	185	59	4	fb6bd7e849ecf4ed9cd9c4e2a946a2d12d62f804
ToppCell	droplet-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IGSF10 MGP LONRF2 KIAA2012	1.08e-04	186	59	4	4e983de6d2515082f9e555f4f949cec84281c140
ToppCell	343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	SUPT20H ZNF789 BOD1L1 PEAK1	1.08e-04	186	59	4	bbb8edea8d8bdc1a469faec1563e40b1f62d7f3d
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PLEKHG1 PEAK1 LRRC15 GGT5	1.08e-04	186	59	4	20340a5b5cc7f07386498a4ef937d6fbc9e347c4
ToppCell	Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|World / Lineage, Cell type, age group and donor	ROS1 RP1 RNF145 AQP5	1.10e-04	187	59	4	81cc8435b2704a9a8287b3f54acaae0f11dd4ac7
ToppCell	RV-07._Pericyte\|World / Chamber and Cluster_Paper	CACNA1C ZEB1 GABBR2 GGT5	1.10e-04	187	59	4	dc274d6bbda619a2c914d84e2b4069cfef1739d1
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CACNA1C PLEKHG1 ZEB1 HPSE2	1.10e-04	187	59	4	c104fbfef2d0bef64077ac721edf2379fd59d547
ToppCell	Control-Fibroblasts-Other_FB\|Control / group, cell type (main and fine annotations)	CACNA1C ZEB1 MGP HPSE2	1.10e-04	187	59	4	bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCell	Fibroblast-A\|World / shred on cell class and cell subclass (v4)	CACNA1D SPATS2L MGP PEAK1	1.12e-04	188	59	4	6740bed5fb8f45b6eea17041894b804214c2a4ae
ToppCell	343B-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	MGP CHAD AQP5 GGT5	1.15e-04	189	59	4	b06471b1bebb990d5146bddfb8002401c6b099a0
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IGSF10 CACNA1C CACNA1D MGP	1.15e-04	189	59	4	a153b83314cf52808f685296cff8c95af3f4983d
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IGSF10 CACNA1C CACNA1D MGP	1.15e-04	189	59	4	e9d5e858e320c6e9913c1ea6a54967d21eda605f
ToppCell	343B-Epithelial_cells-Epithelial-G_(Club-Clara_cells)\|343B / Donor, Lineage, Cell class and subclass (all cells)	MGP CHAD AQP5 GGT5	1.15e-04	189	59	4	a8246acf31f02c85421268245afb651aa8788f14
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1C CACNA1D HPSE2 LONRF2	1.15e-04	189	59	4	45e588b2a4ad9e3ff74e22d9d627ed3571f3b8b8
ToppCell	PND07-28-samps-Mesenchymal-Matrix_fibroblast-FB-3\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	CACNA1D SPATS2L MGP PEAK1	1.17e-04	190	59	4	1196b8ea2c44c7c80f5ee589dd517e6a413f2077
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	CACNA1C CACNA1D HPSE2 PEAK1	1.17e-04	190	59	4	7986586b7c82e91c71102cc8c4d7a689ae63ab4d
ToppCell	facs-Lung-nan-3m-Mesenchymal-pulmonary_interstitial_fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGSF10 MGP HPSE2 LRRC15	1.17e-04	190	59	4	c7bd087f36321cec61b98657433b4d19d135791f
ToppCell	facs-Lung-nan-3m-Mesenchymal-Myofibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGSF10 MGP HPSE2 LRRC15	1.17e-04	190	59	4	834218fcc59df5e7e52de154272f3d55d81d0dac
ToppCell	Control-Fibroblasts\|Control / group, cell type (main and fine annotations)	CACNA1C CACNA1D MGP HPSE2	1.17e-04	190	59	4	3a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IGSF10 CACNA1C CACNA1D MGP	1.17e-04	190	59	4	841cd55861b43578d704418b9bc0af2e8b88323a
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IGSF10 CACNA1C CACNA1D MGP	1.19e-04	191	59	4	b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCell	COPD-Epithelial-Club\|COPD / Disease state, Lineage and Cell class	MGP ROS1 RP1 AQP5	1.19e-04	191	59	4	c909cf5fa0e6519aa93a47d2c3fcd2ae2163cd8d
ToppCell	COVID-19-kidney-vSMC/Pericyte\|kidney / Disease (COVID-19 only), tissue and cell type	CACNA1C ZEB1 MGP HPSE2	1.19e-04	191	59	4	fad8eaa536001b911d05ae2b12150c2398cc6f88
ToppCell	Control-Stromal_mesenchymal\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IGSF10 CACNA1C CACNA1D HPSE2	1.19e-04	191	59	4	14057205ddb9b4bbc582d1358d13cf36d979a61b
ToppCell	Children_(3_yrs)-Epithelial-club_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PLEKHG1 RP1 RNF145 AQP5	1.19e-04	191	59	4	23776c7302cead3881b39127398f3b3e0d27885e
ToppCell	5'-Adult-LymphNode-Mesenchymal\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IGSF10 MGP LONRF2 GGT5	1.19e-04	191	59	4	054e9a79bd1486fd812bc7418fb091664fe3a646
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1C CACNA1D HPSE2 LONRF2	1.19e-04	191	59	4	b133ee1c0e58d00ddd2e4e05b01fd04947524c18
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IGSF10 CACNA1C CACNA1D MGP	1.22e-04	192	59	4	6f4ef24dab544681304b7f8a9dc073e7edaa4cf5
ToppCell	PND14-Mesenchymal-Mesenchymal_structural\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IGSF10 CACNA1D MGP PEAK1	1.22e-04	192	59	4	25492568f9cbe097b7bb1db50d8b817c80ea87d7
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CACNA1C PLEKHG1 ZEB1 HPSE2	1.22e-04	192	59	4	72881b280a415e65f87a80ca1369cbb0b722a0c4
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IGSF10 CACNA1C CACNA1D MGP	1.22e-04	192	59	4	f4fc2b0121f879bab2bee99dfb5ff2c3ca1c0e1b
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IGSF10 CACNA1C CACNA1D MGP	1.22e-04	192	59	4	dcd924d6eb67d33ee9f5d3e8ab6e1d4283d6b708
ToppCell	5'-Adult-LymphNode-Mesenchymal-fibroblastic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IGSF10 MGP LONRF2 GGT5	1.22e-04	192	59	4	d7faa993f68e530ad55185505384ae155d36c222
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IGSF10 CACNA1C CACNA1D MGP	1.22e-04	192	59	4	3d0cb19f037f604253d7d728689aeaa94251e92b
ToppCell	PND14-Mesenchymal-Mesenchymal_structural-Fibroblastic\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IGSF10 CACNA1D MGP PEAK1	1.22e-04	192	59	4	de9c1536d5aee86f9c62acbc54ca8fa581c00f17
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	CACNA1C CACNA1D MGP HPSE2	1.24e-04	193	59	4	9f69edc97b868d23998abc98928a2e89a885ef8a
ToppCell	LAM-Endothelial-LymEndo\|LAM / Condition, Lineage and Cell class	PLEKHG1 ZEB1 LRRC15 GGT5	1.24e-04	193	59	4	68eadc91c2d89edd2412e86dfe134dd7c0ef6ee9
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-VEC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	PLEKHG1 ZEB1 MGP TMEM178B	1.24e-04	193	59	4	9ba688b35a9ead5d04691b3f3f15484f02dbbd0d
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CACNA1D SPATS2L MGP PEAK1	1.24e-04	193	59	4	1b2cc627b2aa002b442358bd1188d470e67ce7d9
ToppCell	nucseq-Mesenchymal-Myocytic-Myocytic_2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CACNA1C ZEB1 MGP LRRC15	1.24e-04	193	59	4	5de87fc94a6e58899ef4124cf4887ed3ff96163a
ToppCell	COVID-19-kidney-FLT1+PLVAP+EC\|kidney / Disease (COVID-19 only), tissue and cell type	CACNA1C PLEKHG1 USP13 ZEB1	1.24e-04	193	59	4	479abb1cd2eb978b8a4fdb900069a6329fc8cade
ToppCell	metastatic_Brain-Fibroblasts-Pericytes\|metastatic_Brain / Location, Cell class and cell subclass	CACNA1C ZEB1 MGP GGT5	1.27e-04	194	59	4	d1889a3e22d5b88461c81ec3ea0e74bb9bf63e60
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CACNA1C CACNA1D HPSE2 TMEM178B	1.27e-04	194	59	4	011e14d9ed1393275f892060e7708ffadcd0767f
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-Secretory/RAS\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	HTR2C MGP RNF145 AQP5	1.27e-04	194	59	4	0cd4363627acd419e00d6d32f6dce10430aa6487
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CACNA1C CACNA1D MGP TMEM178B	1.27e-04	194	59	4	35f132cc38ac133be01834ed0946188aa0757eb4
ToppCell	LPS-antiTNF-Stromal_mesenchymal\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IGSF10 CACNA1C CACNA1D MGP	1.27e-04	194	59	4	6e13549f697f7478b34fe71f7dd9d63c5d3db22e
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-Secretory/RAS-RAS\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	HTR2C MGP RNF145 AQP5	1.27e-04	194	59	4	a58841b34efe673671a9a059238e044a7254b279
ToppCell	Control-Endothelial\|Control / Disease state, Lineage and Cell class	PLEKHG1 ZEB1 MGP GGT5	1.27e-04	194	59	4	485fe5538fabec457b9a51feb641f2a91cbf4e18
ToppCell	COVID-19-kidney-PLVAP+EC\|kidney / Disease (COVID-19 only), tissue and cell type	CACNA1C PLEKHG1 USP13 ZEB1	1.29e-04	195	59	4	a436483fec137584611f86b7a498a4dc2aa19cd3
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CACNA1D SPATS2L MGP PEAK1	1.29e-04	195	59	4	cbe518b465b4ef32797ae6b608219207c08493df
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CACNA1D SPATS2L MGP PEAK1	1.29e-04	195	59	4	b616ee6f1d878935d293c8e0a8bbc5b4385301f0
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CACNA1D SPATS2L MGP PEAK1	1.29e-04	195	59	4	1c1135be421af98cd0077bec1ff2c4158d42aa21
ToppCell	PND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IGSF10 CACNA1D MGP PEAK1	1.29e-04	195	59	4	3a0cad69cfc150a27a0666f612f5294c817197d7
ToppCell	PND03-Mesenchymal-Mesenchymal_structural\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CACNA1D SPATS2L MGP PEAK1	1.29e-04	195	59	4	136b06b0931a69b1241101f68c01c44c70365fd9
ToppCell	PND10-Mesenchymal-Mesenchymal_structural\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CACNA1D SPATS2L MGP PEAK1	1.29e-04	195	59	4	11d421bbbb71425d59cbdd673e052e00d5f0a768
ToppCell	PND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IGSF10 CACNA1D MGP PEAK1	1.29e-04	195	59	4	2b8ee7990267bb52b7e6ae03f509ffebf8908122
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	PLEKHG1 ZEB1 MGP TMEM178B	1.29e-04	195	59	4	023e3c97dd3696d74f002ff8da0c04d876c82aef
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PLEKHG1 RP1 RNF145 AQP5	1.29e-04	195	59	4	dccc32fcf772e2504de7f663ef0a5bd8e23e92fc
ToppCell	RV-02._Fibroblast_II\|World / Chamber and Cluster_Paper	ZEB1 MGP NCOA1 CHD9	1.29e-04	195	59	4	ce90b30dcdb56d4cd925cdb79fd9d7cefd998f48
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CACNA1D SPATS2L MGP PEAK1	1.29e-04	195	59	4	1f005ee1da66b539bd200aaa98f46edbbc7f12e4
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CACNA1D SPATS2L MGP PEAK1	1.29e-04	195	59	4	10f307aef8f4d9e71c501d5bcedb84d3be7a4d1b
ToppCell	PND07-Mesenchymal-Mesenchymal_structural\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CACNA1D SPATS2L MGP PEAK1	1.29e-04	195	59	4	2f9a274b26fc528a85f50933ec2f4db1dc9da0ca
Drug	Cinnarizine	CACNA1C CACNA1D CACNA1F CACNA1S	4.41e-09	9	57	4	DB00568
Drug	Nimodipine	CACNA1C CACNA1D CACNA1F CACNA1S	4.41e-09	9	57	4	DB00393
Drug	Mibefradil	CACNA1C CACNA1D CACNA1F CACNA1S	1.15e-08	11	57	4	DB01388
Drug	Verapamil	CACNA1C CACNA1D CACNA1F CACNA1S	6.28e-08	16	57	4	DB00661
Drug	Nilvadipine	CACNA1C CACNA1D CACNA1S	1.48e-07	5	57	3	DB06712
Drug	Nisoldipine	CACNA1C CACNA1D CACNA1S	1.48e-07	5	57	3	DB00401
Drug	CPU-23	CACNA1C CACNA1D CACNA1S	2.96e-07	6	57	3	CID003036051
Drug	Amlodipine	CACNA1C CACNA1D CACNA1S	5.17e-07	7	57	3	DB00381
Drug	Isradipine	CACNA1C CACNA1D CACNA1S	5.17e-07	7	57	3	DB00270
Drug	AC1L2AC7	CACNA1C CACNA1D CACNA1F CACNA1S TONSL	8.17e-07	69	57	5	CID000068733
Drug	Nifedipine	CACNA1C CACNA1D CACNA1S	8.26e-07	8	57	3	DB01115
Drug	Nitrendipine	CACNA1C CACNA1D CACNA1S	8.26e-07	8	57	3	DB01054
Drug	ethosuximide	CACNA1C CACNA1D CACNA1F CACNA1S GABBR2	1.16e-06	74	57	5	CID000003291
Drug	CNS 1145	CACNA1C CACNA1D CACNA1F CACNA1S	1.37e-06	33	57	4	CID000190902
Drug	IHC-64	CACNA1C CACNA1D CACNA1F CACNA1S	1.37e-06	33	57	4	CID000162753
Drug	Dantrolene-13C3	CACNA1C CACNA1D CACNA1F CACNA1S MGP AQP5	1.67e-06	145	57	6	CID000002951
Drug	lindane	CACNA1C CACNA1D CACNA1F CACNA1S TONSL GABBR2	2.37e-06	154	57	6	CID000000727
Drug	Felodipine	CACNA1C CACNA1D CACNA1S	2.42e-06	11	57	3	DB01023
Drug	AC1L1JG6	CACNA1C CACNA1D CACNA1S	5.31e-06	14	57	3	CID000005026
Drug	FPL 64176	CACNA1C CACNA1D CACNA1S	6.63e-06	15	57	3	CID000003423
Drug	KW-3049	CACNA1C CACNA1D CACNA1F CACNA1S	7.46e-06	50	57	4	CID000002324
Drug	Hypertensin II	CACNA1C CACNA1D ZEB1 TONSL NCOA1 LONRF2 MAP3K1 STAT5A	1.10e-05	429	57	8	CID000025476
Drug	AC1NBU2S	CACNA1C CACNA1D CACNA1F CACNA1S TONSL	1.11e-05	117	57	5	CID004473765
Drug	Cinildipine	CACNA1C CACNA1D CACNA1F CACNA1S	1.18e-05	56	57	4	CID000002752
Drug	1-alpha-25-dihydroxycholecalciferol	CACNA1C CACNA1D NCOA3 CACNA1S HTR2C MGP NCOA1 CHD9 SCEL RNF145 MAP3K1	1.33e-05	909	57	11	CID000002524
Drug	nilvadipine	CACNA1C CACNA1D CACNA1F CACNA1S	1.55e-05	60	57	4	CID000004494
Drug	pimozide	CACNA1C CACNA1D CACNA1F CACNA1S HTR2C	1.66e-05	127	57	5	CID000016362
Drug	IAA-94	CACNA1C CACNA1D CACNA1F CACNA1S	1.66e-05	61	57	4	CID000003667
Drug	phenytoin	CACNA1C CACNA1D CACNA1F CACNA1S MGP TONSL	1.78e-05	219	57	6	CID000001775
Drug	enzacamene	CACNA1C CACNA1D CACNA1F CYP11B1 NCOA1	1.79e-05	129	57	5	ctd:C038939
Drug	lercanidipine	CACNA1C CACNA1D CACNA1F CACNA1S	1.88e-05	63	57	4	CID000065866
Drug	NSC759256	CACNA1C CACNA1D CACNA1S GABBR2	1.88e-05	63	57	4	CID000125889
Drug	lanthanum	CACNA1C CACNA1D CACNA1F CACNA1S TPTE2	2.30e-05	136	57	5	CID000023926
Drug	gallopamil	CACNA1C CACNA1D CACNA1F CACNA1S	2.41e-05	67	57	4	CID000001234
Drug	nimodipine	CACNA1C CACNA1D CACNA1F CACNA1S GABBR2	3.14e-05	145	57	5	CID000004497
Drug	CAS 298-57-7	CACNA1C CACNA1D CACNA1F CACNA1S	3.38e-05	73	57	4	CID000002761
Drug	NSC-686960	CACNA1C CACNA1D	3.68e-05	4	57	2	CID000192816
Drug	NSC-609423	GABBR2 GGT5	3.68e-05	4	57	2	CID000355553
Drug	nisoldipine	CACNA1C CACNA1D CACNA1F CACNA1S	4.39e-05	78	57	4	CID000004499
Drug	N-cyclopentyl-N-cyclobutylformamide	CACNA1C CACNA1D CACNA1F CACNA1S	4.61e-05	79	57	4	CID005287890
Drug	clobazam	CACNA1C CACNA1D ZEB1	5.19e-05	29	57	3	CID000002789
Drug	aldosterone	CACNA1C CACNA1D CACNA1F CACNA1S CYP11B1 TONSL LONRF2	5.80e-05	397	57	7	CID000005839
Drug	mercury	CACNA1C CACNA1D CACNA1F CACNA1S CYP11B1 TONSL AQP5 SCAF4	5.80e-05	542	57	8	CID000023931
Drug	AC1L1B1W	CACNA1C CACNA1D ZEB1 GABBR2	5.87e-05	84	57	4	CID000001248
Drug	B 874-67	CACNA1C CACNA1D	6.13e-05	5	57	2	CID000195466
Drug	methyl beta-aminocrotonate	CACNA1C CACNA1D	6.13e-05	5	57	2	CID000084253
Drug	nemadipine-A	CACNA1C CACNA1D	6.13e-05	5	57	2	CID002856102
Drug	gabapentin	CACNA1C CACNA1D CACNA1F CACNA1S GABBR2	6.51e-05	169	57	5	CID000003446
Drug	felodipine	CACNA1C CACNA1D CACNA1F CACNA1S CYP11B1	6.51e-05	169	57	5	CID000003333
Drug	riluzole	CACNA1C CACNA1D CACNA1F CACNA1S GABBR2	7.47e-05	174	57	5	CID000005070
Drug	papaverine	CACNA1C CACNA1D CACNA1F CACNA1S ODF2	7.89e-05	176	57	5	CID000004680
Drug	AC1NUZ8M	CACNA1C CACNA1D CACNA1S TONSL	8.37e-05	92	57	4	CID000073211
Drug	picrotoxin	CACNA1C CACNA1D ZEB1 TONSL GABBR2	9.00e-05	181	57	5	CID000031304
Drug	butamben	NCOA3 NCOA1	9.18e-05	6	57	2	ctd:C004605
Drug	Magnesium Sulfate	CACNA1C CACNA1S	9.18e-05	6	57	2	DB00653
Drug	manidipine	CACNA1C CACNA1D CACNA1F CACNA1S	9.48e-05	95	57	4	CID000004008
Drug	FG 7142	ZEB1 HTR2C GABBR2	1.00e-04	36	57	3	CID000004375
Drug	isotetrandrine	CACNA1C CACNA1D CACNA1F CACNA1S	1.03e-04	97	57	4	CID000005422
Drug	nitrendipine	CACNA1C CACNA1D CACNA1F CACNA1S	1.07e-04	98	57	4	CID000004507
Drug	isradipine	CACNA1C CACNA1D CACNA1F CACNA1S	1.16e-04	100	57	4	CID000003784
Drug	baclofen	CACNA1C CACNA1D CACNA1F CACNA1S GABBR2	1.16e-04	191	57	5	CID000002284
Drug	NSC759576	CACNA1C CACNA1D CACNA1F CACNA1S TONSL	1.16e-04	191	57	5	CID000003075
Drug	Cinoxacin [28657-80-9]; Down 200; 15.2uM; HL60; HT_HG-U133A	PITPNM1 N4BP2L1 ZEB1 MAP3K1 STAT5A	1.19e-04	192	57	5	2722_DN
Drug	ivermectin	TONSL CHAD GABBR2 TEP1	1.20e-04	101	57	4	CID006435110
Drug	alprazolam	ZEB1 HTR2C CYP11B1 TONSL GABBR2	1.22e-04	193	57	5	CID000002118
Drug	bp G	ZEB1 ROS1 GABBR2	1.28e-04	39	57	3	CID000448110
Drug	(cis-) Nanophine [5072-45-7]; Down 200; 26.8uM; PC3; HT_HG-U133A	PITPNM1 SUPT20H CIZ1 TEP1 LRRC15	1.28e-04	195	57	5	3806_DN
Drug	Aminohippuric acid [61-78-9]; Up 200; 20.6uM; MCF7; HT_HG-U133A	CACNA1D CD247 ZEB1 PCNX1 GABBR2	1.34e-04	197	57	5	5394_UP
Drug	loperamide	CACNA1C CACNA1D CACNA1F CACNA1S	1.40e-04	105	57	4	CID000003954
Drug	Tropicamide [1508-75-4]; Up 200; 14uM; MCF7; HT_HG-U133A	CACNA1D CD247 AQP5 MAP3K1 LRRC15	1.40e-04	199	57	5	2309_UP
Drug	1,5-benzothiazepin-4(5H)-one	CACNA1C CACNA1D	1.71e-04	8	57	2	CID000358939
Drug	gamma-aminobutyric acid	CACNA1C CACNA1D CACNA1F CACNA1S ZEB1 HTR2C GABBR2	1.74e-04	474	57	7	CID000000119
Drug	potassium	CACNA1C CACNA1D CACNA1F CACNA1S HTR2C CYP11B1 TONSL GABBR2 LONRF2 GGT5	1.80e-04	1008	57	10	CID000000813
Drug	hydroxyisocaproate	CACNA1C CACNA1D ROS1	1.83e-04	44	57	3	CID000083697
Drug	Androstenedione	NCOA3 CYP11B1 NCOA1	1.96e-04	45	57	3	ctd:D000735
Drug	h PM	CACNA1C CACNA1D CACNA1S	1.96e-04	45	57	3	CID005494424
Drug	lamotrigine	CACNA1C CACNA1D CACNA1F CACNA1S	2.05e-04	116	57	4	CID000003878
Drug	torcetrapib	CACNA1C NCOA3 CYP11B1 CHD9 BOD1L1 LONRF2	2.09e-04	342	57	6	ctd:C483909
Drug	3-aminopropylphosphonate	GABBR2 GGT5	2.19e-04	9	57	2	CID000097587
Drug	raloxifene	KIF20A NCOA3 ZEB1 MGP TONSL NCOA1	2.41e-04	351	57	6	CID000005035
Drug	D-salicin	ORC3 HPSE2 GABBR2	2.53e-04	49	57	3	CID000005145
Drug	alpha-hydroxyalprazolam	ZEB1 HPSE2	2.74e-04	10	57	2	CID000162244
Drug	AC1L3TPS	CACNA1C CACNA1D	2.74e-04	10	57	2	CID000121952
Drug	bepridil	CACNA1C CACNA1D CACNA1F CACNA1S	2.82e-04	126	57	4	CID000002351
Drug	amlodipine	CACNA1C CACNA1D CACNA1F CACNA1S	2.82e-04	126	57	4	CID000002162
Drug	2-(3-hydroxypropoxy)-1,25-dihydroxyvitamin D3	NCOA3 NCOA1	3.34e-04	11	57	2	ctd:C061137
Drug	NSC 403654	NCOA3 GABBR2	3.34e-04	11	57	2	CID000009319
Drug	Barium permanganate	CACNA1C CACNA1D CACNA1S GABBR2	3.46e-04	133	57	4	CID000024587
Drug	valproate	CACNA1C CACNA1D CACNA1F CACNA1S TONSL GABBR2	3.73e-04	381	57	6	CID000003121
Drug	octylmethoxycinnamate	CACNA1C CACNA1D CACNA1F CYP11B1	4.09e-04	139	57	4	ctd:C118580
Drug	cobalt-60	CACNA1C CACNA1D CACNA1F CACNA1S RP1 GGT5	4.22e-04	390	57	6	CID000061492
Drug	4,4'-hexafluorisopropylidene diphenol	NCOA3 MGP CYP11B1 NCOA1	4.43e-04	142	57	4	ctd:C583074
Drug	isovalerate	CACNA1C CACNA1D CACNA1S GABBR2	4.55e-04	143	57	4	CID000010430
Drug	dihydroxy-vitamin D3	NCOA3 NCOA1	4.72e-04	13	57	2	ctd:C118756
Drug	nicardipine	CACNA1C CACNA1D CACNA1F CACNA1S	4.80e-04	145	57	4	CID000004473
Disease	Timothy syndrome (implicated_via_orthology)	CACNA1C CACNA1D CACNA1F CACNA1S	1.34e-11	4	58	4	DOID:0060173 (implicated_via_orthology)
Disease	Duchenne muscular dystrophy (implicated_via_orthology)	CACNA1C CACNA1D CACNA1F CACNA1S	7.55e-07	36	58	4	DOID:11723 (implicated_via_orthology)
Disease	Conn Syndrome	CACNA1D CYP11B1	5.67e-05	6	58	2	C1384514
Disease	Hyperaldosteronism	CACNA1D CYP11B1	5.67e-05	6	58	2	C0020428
Disease	acute lymphoblastic leukemia, response to antineoplastic agent	NCOA3 SPATS2L	6.36e-04	19	58	2	EFO_0000220, GO_0097327
Disease	hypertension, COVID-19	PLEKHG1 CACNA1D	1.29e-03	27	58	2	EFO_0000537, MONDO_0100096
Disease	pyridoxate measurement	CACNA1D EMILIN2	1.70e-03	31	58	2	EFO_0010527
Disease	brain infarction (biomarker_via_orthology)	MGP CYP11B1	1.93e-03	33	58	2	DOID:3454 (biomarker_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
NSANPNQDQNARRRK	HTR2C	276	P28335
LNLQRNNFPVLAANS	CHAD	56	O15335
LNARGNLAVNALNNN	AQP5	111	P55064
QQQARFIQPRPTLNQ	RCOR3	436	Q9P2K3
NPQRNLQRSNNSLAS	RBM43	191	Q6ZSC3
TLKDPQNNRIFQRQN	OVOS1	141	Q6IE37
QNNRIFQRQNVTSFR	OVOS1	146	Q6IE37
NRNNNFQTFPQAVLL	CACNA1F	1361	O60840
QQRLLRQAQTRPFQQ	MED12L	1891	Q86YW9
GNNRQNAPLTSIQIR	NEDD1	576	Q8NHV4
AGQQQELVFLRNRNP	PCNX1	1951	Q96RV3
RNRAALSQKPLNNNN	PEAK1	106	Q9H792
FRSQLESQAQRQIQP	KIAA2012	136	Q0VF49
AGQARSLQRQQQPEA	LONRF2	201	Q1L5Z9
LIFALNALRRNPNNS	HPSE2	221	Q8WWQ2
PHLNKNQLRNNIRQQ	BOD1L1	106	Q8NFC6
SLRSQQNRNNLNPGQ	CHD9	176	Q3L8U1
QQNFVNNHNPKGRLR	IGSF10	1206	Q6WRI0
INRNNNFQTFPQAVL	CACNA1C	1441	Q13936
NRNNNFQTFPQAVLL	CACNA1S	1301	Q13698
QGQNQLYNELNLGRR	CD247	66	P20963
QSRLRRQQQNAPLFG	CCDC102A	506	Q96A19
ARNPNVQQALRQESL	CYP11B1	331	P15538
DRGQNQTQRPFFLNV	GGT5	546	P36269
PDAATQNRRFQFTQN	GABBR2	751	O75899
NNLRARLQEPSAQAN	EMILIN2	381	Q9BXX0
RLSLSQPILSQQNNF	CEP295	936	Q9C0D2
VAQANRAQGQRQSPR	DNAJC22	56	Q8N4W6
QQFRNDNRQQFNSGR	SCAF4	981	O95104
LNPFINRRNANTFIS	MGP	31	P08493
NQINRNNNFQTFPQA	CACNA1D	1381	Q01668
AANQRLQQAGNVLRQ	C19orf25	71	Q9UFG5
RRQFQSQLADLQQLP	ODF2	586	Q5BJF6
NFLSNNQCENIRRLP	ORC3	356	Q9UBD5
LLNNRFQGSRTNLNQ	RP1	2071	P56715
QTVQQQPLAGSRRNQ	MAP3K1	521	Q13233
RRQLNLSNPDFNIQQ	SYT9	171	Q86SS6
IYNNNNNLPLRASRS	TMEM178B	56	H3BS89
KQNGSSNQRRRFNPQ	SPATS2L	426	Q9NUQ6
SLQNNRLRQLPGNIF	LRRC15	371	Q8TF66
SQGCPNRDRQIRNQQ	SPATA31A6	1271	Q5VVP1
QNRQAILNQFAATAP	NCOA1	1071	Q15788
QRLQGQQFLNQSRQA	NCOA3	1176	Q9Y6Q9
QENFSNQRIPAQGIR	PRDM7	451	Q9NQW5
RIQAQFAQLAQLSPQ	STAT5A	181	P42229
NLQQFFPQATRQSLL	CIZ1	146	Q9ULV3
QQPNVFNLSGAERRQ	PITPNM1	121	O00562
QFLNRNQRLQPSAQA	TEP1	1011	Q99973
QNQQNRSKQNLVPFR	KIF20A	446	O95235
AQQAQRPQLQRQVLQ	TONSL	421	Q96HA7
PEIFTNNQRNQDLAN	SCEL	496	O95171
PQQRFQLSSAFQQQQ	SUPT20H	716	Q8NEM7
AVQALQALQRQPNAA	PHC1	36	P78364
RILQPTATNQQNKRN	ROS1	1311	P08922
KQANPRRNNVTNYNT	ZEB1	11	P37275
NTSFIQNNRLCLPRN	TPTE2	481	Q6XPS3
VNRNLPLNAQIATQN	PLEKHG1	1251	Q9ULL1
QQIQRSSLSNNPLFQ	RNF145	36	Q96MT1
FQRNQAIQALRATNN	USP13	741	Q92995
SRGFLQNLNLIQDQN	ZNF789	151	Q5FWF6
LQSFGRLSLQPQQQQ	N4BP2L1	6	Q5TBK1
RNQDRNNALPSNNAR	N4BP2L1	196	Q5TBK1