Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	N-acetylglucosamine-6-sulfatase activity	SULF2 SULF1	3.03e-05	3	64	2	GO:0008449
GeneOntologyMolecularFunction	extracellular matrix structural constituent	COL4A4 COL5A1 FRAS1 COL27A1 NID1	3.41e-04	188	64	5	GO:0005201
GeneOntologyMolecularFunction	extracellular matrix structural constituent conferring tensile strength	COL4A4 COL5A1 COL27A1	4.32e-04	46	64	3	GO:0030020
GeneOntologyMolecularFunction	actin binding	DST SPATA31A1 SPATA31A3 MYO7B SPATA31A7 SPATA31A5 MYO16	8.35e-04	479	64	7	GO:0003779
GeneOntologyMolecularFunction	arylsulfatase activity	SULF2 SULF1	8.98e-04	14	64	2	GO:0004065
GeneOntologyBiologicalProcess	glomerular basement membrane development	COL4A4 SULF2 SULF1 NID1	1.75e-08	10	64	4	GO:0032836
GeneOntologyBiologicalProcess	extracellular matrix organization	COL4A4 COL5A1 SULF2 SULF1 COL27A1 APBB1 ADAMTS18 NID1 ADAMTSL2	2.35e-06	377	64	9	GO:0030198
GeneOntologyBiologicalProcess	extracellular structure organization	COL4A4 COL5A1 SULF2 SULF1 COL27A1 APBB1 ADAMTS18 NID1 ADAMTSL2	2.40e-06	378	64	9	GO:0043062
GeneOntologyBiologicalProcess	external encapsulating structure organization	COL4A4 COL5A1 SULF2 SULF1 COL27A1 APBB1 ADAMTS18 NID1 ADAMTSL2	2.45e-06	379	64	9	GO:0045229
GeneOntologyBiologicalProcess	esophagus smooth muscle contraction	SULF2 SULF1	9.48e-06	2	64	2	GO:0014846
GeneOntologyBiologicalProcess	glomerulus development	COL4A4 SULF2 SULF1 NID1	9.62e-05	77	64	4	GO:0032835
GeneOntologyBiologicalProcess	kidney development	COL4A4 FRAS1 SULF2 SULF1 NID1 TIMELESS SMAD1	1.51e-04	372	64	7	GO:0001822
GeneOntologyBiologicalProcess	renal system development	COL4A4 FRAS1 SULF2 SULF1 NID1 TIMELESS SMAD1	1.89e-04	386	64	7	GO:0072001
GeneOntologyBiologicalProcess	nephron development	COL4A4 SULF2 SULF1 NID1 TIMELESS	2.06e-04	174	64	5	GO:0072006
GeneOntologyBiologicalProcess	chondrocyte development	SULF2 SULF1 COL27A1	2.79e-04	41	64	3	GO:0002063
GeneOntologyCellularComponent	extracellular matrix	COL4A4 COL5A1 FRAS1 DST SULF1 COL27A1 ADAMTS18 NID1 CFP ADAMTSL2	2.84e-05	656	64	10	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	COL4A4 COL5A1 FRAS1 DST SULF1 COL27A1 ADAMTS18 NID1 CFP ADAMTSL2	2.91e-05	658	64	10	GO:0030312
GeneOntologyCellularComponent	complex of collagen trimers	COL4A4 COL5A1 COL27A1	3.50e-05	21	64	3	GO:0098644
GeneOntologyCellularComponent	basement membrane	COL4A4 COL5A1 FRAS1 DST NID1	3.61e-05	122	64	5	GO:0005604
GeneOntologyCellularComponent	collagen-containing extracellular matrix	COL4A4 COL5A1 FRAS1 DST SULF1 COL27A1 NID1 CFP	2.06e-04	530	64	8	GO:0062023
GeneOntologyCellularComponent	fibrillar collagen trimer	COL5A1 COL27A1	5.97e-04	12	64	2	GO:0005583
GeneOntologyCellularComponent	banded collagen fibril	COL5A1 COL27A1	5.97e-04	12	64	2	GO:0098643
MousePheno	abnormal sternebra morphology	FRAS1 SULF2 SULF1 COL27A1	2.70e-05	52	47	4	MP:0004322
MousePheno	sternebra fusion	SULF2 SULF1 COL27A1	3.32e-05	19	47	3	MP:0010082
Domain	DUF4599	SPATA31A3 SPATA31A7 SPATA31A5	7.87e-06	12	63	3	PF15371
Domain	DUF4599	SPATA31A3 SPATA31A7 SPATA31A5	7.87e-06	12	63	3	IPR027970
Domain	Extracellular_sulfatase	SULF2 SULF1	1.12e-05	2	63	2	IPR014615
Domain	Extracellular_sulfatase_C	SULF2 SULF1	1.12e-05	2	63	2	IPR024609
Domain	DUF3740	SULF2 SULF1	1.12e-05	2	63	2	PF12548
Domain	Znf_C2H2-like	RLF ZNF12 ZNF677 ZNF142 ZNF148 ZNF473 REST ZNF227 ZNF768 RNF138	3.08e-04	796	63	10	IPR015880
Domain	Znf_C2H2	RLF ZNF12 ZNF677 ZNF142 ZNF148 ZNF473 REST ZNF227 ZNF768 RNF138	3.37e-04	805	63	10	IPR007087
Domain	ZnF_C2H2	RLF ZNF12 ZNF677 ZNF142 ZNF148 ZNF473 REST ZNF227 ZNF768 RNF138	3.47e-04	808	63	10	SM00355
Domain	-	RLF ZNF12 ZNF677 ZNF142 ZNF148 ZNF473 REST ZNF227 ZNF768	4.30e-04	679	63	9	3.30.160.60
Domain	zf-C2H2	RLF ZNF12 ZNF677 ZNF142 ZNF148 ZNF473 REST ZNF227 ZNF768	4.99e-04	693	63	9	PF00096
Domain	Znf_C2H2/integrase_DNA-bd	RLF ZNF12 ZNF677 ZNF142 ZNF148 ZNF473 REST ZNF227 ZNF768	5.04e-04	694	63	9	IPR013087
Domain	Fib_collagen_C	COL5A1 COL27A1	6.04e-04	11	63	2	IPR000885
Domain	COLFI	COL5A1 COL27A1	6.04e-04	11	63	2	PF01410
Domain	NC1_FIB	COL5A1 COL27A1	6.04e-04	11	63	2	PS51461
Domain	Fib_collagen_C	COL5A1 COL27A1	6.04e-04	11	63	2	PD002078
Domain	COLFI	COL5A1 COL27A1	6.04e-04	11	63	2	SM00038
Domain	PLAC	ADAMTS18 ADAMTSL2	9.93e-04	14	63	2	PF08686
Domain	ZINC_FINGER_C2H2_2	RLF ZNF12 ZNF677 ZNF142 ZNF148 ZNF473 REST ZNF227 ZNF768	1.10e-03	775	63	9	PS50157
Domain	ZINC_FINGER_C2H2_1	RLF ZNF12 ZNF677 ZNF142 ZNF148 ZNF473 REST ZNF227 ZNF768	1.13e-03	777	63	9	PS00028
Domain	TSP_1	ADAMTS18 CFP ADAMTSL2	1.26e-03	63	63	3	PF00090
Domain	Sulfatase_CS	SULF2 SULF1	1.30e-03	16	63	2	IPR024607
Domain	TSP1	ADAMTS18 CFP ADAMTSL2	1.38e-03	65	63	3	SM00209
Domain	TSP1_rpt	ADAMTS18 CFP ADAMTSL2	1.38e-03	65	63	3	IPR000884
Domain	TSP1	ADAMTS18 CFP ADAMTSL2	1.38e-03	65	63	3	PS50092
Domain	SULFATASE_1	SULF2 SULF1	1.47e-03	17	63	2	PS00523
Domain	SULFATASE_2	SULF2 SULF1	1.47e-03	17	63	2	PS00149
Domain	Sulfatase	SULF2 SULF1	1.65e-03	18	63	2	PF00884
Domain	Sulfatase_N	SULF2 SULF1	1.65e-03	18	63	2	IPR000917
Domain	PLAC	ADAMTS18 ADAMTSL2	1.85e-03	19	63	2	PS50900
Domain	PLAC	ADAMTS18 ADAMTSL2	1.85e-03	19	63	2	IPR010909
Domain	ADAM_spacer1	ADAMTS18 ADAMTSL2	2.71e-03	23	63	2	IPR010294
Domain	TSPN	COL5A1 COL27A1	2.71e-03	23	63	2	SM00210
Domain	ADAM_spacer1	ADAMTS18 ADAMTSL2	2.71e-03	23	63	2	PF05986
Domain	Peptidase_M12B_ADAM-TS	ADAMTS18 ADAMTSL2	2.95e-03	24	63	2	IPR013273
Domain	Collagen	COL4A4 COL5A1 COL27A1	2.97e-03	85	63	3	IPR008160
Domain	Collagen	COL4A4 COL5A1 COL27A1	2.97e-03	85	63	3	PF01391
Domain	PID	LDLRAP1 APBB1	4.00e-03	28	63	2	PF00640
Domain	Alkaline_phosphatase_core	SULF2 SULF1	4.89e-03	31	63	2	IPR017850
Domain	Alkaline_Pase-like_a/b/a	SULF2 SULF1	4.89e-03	31	63	2	IPR017849
Domain	-	SULF2 SULF1	4.89e-03	31	63	2	3.40.720.10
Domain	PID	LDLRAP1 APBB1	5.20e-03	32	63	2	PS01179
Domain	Myb_DNA-binding	TERB1 MYBL1	6.20e-03	35	63	2	PF00249
Domain	Myosin_head_motor_dom	MYO7B MYO16	7.28e-03	38	63	2	IPR001609
Domain	MYOSIN_MOTOR	MYO7B MYO16	7.28e-03	38	63	2	PS51456
Domain	LAM_G_DOMAIN	COL5A1 COL27A1	7.28e-03	38	63	2	PS50025
Domain	Myosin_head	MYO7B MYO16	7.28e-03	38	63	2	PF00063
Domain	MYSc	MYO7B MYO16	7.28e-03	38	63	2	SM00242
Pathway	REACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES	COL4A4 COL5A1 DST COL27A1	5.35e-05	61	48	4	M27103
Pubmed	The testis-specific VAD1.3/AEP1 interacts with β-actin and syntaxin 1 and directs peri-nuclear/Golgi expression with bipartite nucleus localization (BNL) sequence.	SPATA31A1 SPATA31A3 SPATA31A7 SPATA31A5	1.56e-10	6	64	4	20850414
Pubmed	Targeted disruption of the spermatid-specific gene Spata31 causes male infertility.	SPATA31A1 SPATA31A3 SPATA31A7 SPATA31A5	1.56e-10	6	64	4	25930072
Pubmed	Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species.	SPATA31A1 SPATA31A3 SPATA31A7 SPATA31A5	1.08e-07	24	64	4	32212159
Pubmed	Cloning and characterization of two extracellular heparin-degrading endosulfatases in mice and humans.	SULF2 SULF1	3.33e-06	2	64	2	12368295
Pubmed	Heparan sulfate 6-O-endosulfatases: discrete in vivo activities and functional co-operativity.	SULF2 SULF1	3.33e-06	2	64	2	16901266
Pubmed	Overexpression of Sulf2 in idiopathic pulmonary fibrosis.	SULF2 SULF1	3.33e-06	2	64	2	23418199
Pubmed	Regulation of fractone heparan sulfate composition in young and aged subventricular zone neurogenic niches.	SULF2 SULF1	3.33e-06	2	64	2	34324645
Pubmed	Sulf loss influences N-, 2-O-, and 6-O-sulfation of multiple heparan sulfate proteoglycans and modulates fibroblast growth factor signaling.	SULF2 SULF1	3.33e-06	2	64	2	18687675
Pubmed	Loss of endothelial sulfatase-1 after experimental sepsis attenuates subsequent pulmonary inflammatory responses.	SULF2 SULF1	3.33e-06	2	64	2	31461325
Pubmed	HSulf-1 and HSulf-2 are potent inhibitors of myeloma tumor growth in vivo.	SULF2 SULF1	3.33e-06	2	64	2	16192265
Pubmed	Functional consequences of the subdomain organization of the sulfs.	SULF2 SULF1	3.33e-06	2	64	2	19520866
Pubmed	Epithelial Deletion of Sulf2 Exacerbates Bleomycin-Induced Lung Injury, Inflammation, and Mortality.	SULF2 SULF1	3.33e-06	2	64	2	28657777
Pubmed	The SULFs, extracellular sulfatases for heparan sulfate, promote the migration of corneal epithelial cells during wound repair.	SULF2 SULF1	3.33e-06	2	64	2	23950901
Pubmed	SULF1/SULF2 splice variants differentially regulate pancreatic tumour growth progression.	SULF2 SULF1	3.33e-06	2	64	2	24726914
Pubmed	Endosulfatases SULF1 and SULF2 limit Chlamydia muridarum infection.	SULF2 SULF1	3.33e-06	2	64	2	23480519
Pubmed	Expression of novel extracellular sulfatases Sulf-1 and Sulf-2 in normal and osteoarthritic articular cartilage.	SULF2 SULF1	3.33e-06	2	64	2	18507859
Pubmed	Differential involvement of the extracellular 6-O-endosulfatases Sulf1 and Sulf2 in brain development and neuronal and behavioural plasticity.	SULF2 SULF1	3.33e-06	2	64	2	20394677
Pubmed	Heparan sulfate 6-O-endosulfatases, Sulf1 and Sulf2, regulate glomerular integrity by modulating growth factor signaling.	SULF2 SULF1	3.33e-06	2	64	2	26764203
Pubmed	SULFs in human neoplasia: implication as progression and prognosis factors.	SULF2 SULF1	3.33e-06	2	64	2	21599997
Pubmed	SULF1/SULF2 reactivation during liver damage and tumour growth.	SULF2 SULF1	3.33e-06	2	64	2	27013228
Pubmed	Short SULF1/SULF2 splice variants predominate in mammary tumours with a potential to facilitate receptor tyrosine kinase-mediated cell signalling.	SULF2 SULF1	3.33e-06	2	64	2	27294358
Pubmed	Heparan Sulfate-Editing Extracellular Sulfatases Enhance VEGF Bioavailability for Ischemic Heart Repair.	SULF2 SULF1	3.33e-06	2	64	2	31434553
Pubmed	Extracellular sulfatases support cartilage homeostasis by regulating BMP and FGF signaling pathways.	SULF2 SULF1	3.33e-06	2	64	2	20479257
Pubmed	Multi-tasking Sulf1/Sulf2 enzymes do not only facilitate extracellular cell signalling but also participate in cell cycle related nuclear events.	SULF2 SULF1	3.33e-06	2	64	2	29360432
Pubmed	Sulf1 and Sulf2 Differentially Modulate Heparan Sulfate Proteoglycan Sulfation during Postnatal Cerebellum Development: Evidence for Neuroprotective and Neurite Outgrowth Promoting Functions.	SULF2 SULF1	3.33e-06	2	64	2	26448642
Pubmed	Enhanced tumorigenic potential of colorectal cancer cells by extracellular sulfatases.	SULF2 SULF1	3.33e-06	2	64	2	25477293
Pubmed	Diffusion magnetic resonance tractography-based evaluation of commissural fiber abnormalities in a heparan sulfate endosulfatase-deficient mouse brain.	SULF2 SULF1	3.33e-06	2	64	2	35131262
Pubmed	Organ-specific sulfation patterns of heparan sulfate generated by extracellular sulfatases Sulf1 and Sulf2 in mice.	SULF2 SULF1	3.33e-06	2	64	2	22298771
Pubmed	Abnormal Pyramidal Decussation and Bilateral Projection of the Corticospinal Tract Axons in Mice Lacking the Heparan Sulfate Endosulfatases, Sulf1 and Sulf2.	SULF2 SULF1	3.33e-06	2	64	2	32038163
Pubmed	Expression of Heparan Sulfate Endosulfatases in the Adult Mouse Brain: Co-expression of Sulf1 and Dopamine D1/D2 Receptors.	SULF2 SULF1	3.33e-06	2	64	2	34489650
Pubmed	Sulfs are regulators of growth factor signaling for satellite cell differentiation and muscle regeneration.	SULF2 SULF1	3.33e-06	2	64	2	17920055
Pubmed	Dystonin deficiency reduces taste buds and fungiform papillae in the anterior part of the tongue.	SULF2 DST	3.33e-06	2	64	2	17156752
Pubmed	WT1-dependent sulfatase expression maintains the normal glomerular filtration barrier.	SULF2 SULF1	9.99e-06	3	64	2	21719793
Pubmed	Gene trap disruption of the mouse heparan sulfate 6-O-endosulfatase gene, Sulf2.	SULF2 SULF1	9.99e-06	3	64	2	17116694
Pubmed	Expression of the heparan sulfate 6-O-endosulfatases, Sulf1 and Sulf2, in the avian and mammalian inner ear suggests a role for sulfation during inner ear development.	SULF2 SULF1	9.99e-06	3	64	2	25370455
Pubmed	Heparan sulfate 6-O-endosulfatases (Sulfs) coordinate the Wnt signaling pathways to regulate myoblast fusion during skeletal muscle regeneration.	SULF2 SULF1	9.99e-06	3	64	2	22865881
Pubmed	Desulfation of Heparan Sulfate by Sulf1 and Sulf2 Is Required for Corticospinal Tract Formation.	SULF2 SULF1	9.99e-06	3	64	2	29062064
Pubmed	Sulf1 and Sulf2 expression in the nervous system and its role in limiting neurite outgrowth in vitro.	SULF2 SULF1	9.99e-06	3	64	2	25448158
Pubmed	The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.	COL4A4 COL5A1 FRAS1 COL27A1 NID1	1.46e-05	167	64	5	22159717
Pubmed	Secreted sulfatases Sulf1 and Sulf2 have overlapping yet essential roles in mouse neonatal survival.	SULF2 SULF1	2.00e-05	4	64	2	17593974
Pubmed	Assignment of the human helix-loop-helix transcription factor gene musculin/activated B-cell factor-1 (MSC) to chromosome 8q21 and its mouse homologue (Msc) to the proximal region of chromosome 1.	DST MYBL1	2.00e-05	4	64	2	10198176
Pubmed	Distinct expression patterns of Sulf1 and Hs6st1 spatially regulate heparan sulfate sulfation during prostate development.	SULF2 SULF1	2.00e-05	4	64	2	23074159
Pubmed	Characterization of the mouse JAB1 cDNA and protein.	DST MYBL1	2.00e-05	4	64	2	10721695
Pubmed	HSulf sulfatases catalyze processive and oriented 6-O-desulfation of heparan sulfate that differentially regulates fibroblast growth factor activity.	SULF2 SULF1	2.00e-05	4	64	2	23457216
Pubmed	Expression regulation and function of heparan sulfate 6-O-endosulfatases in the spermatogonial stem cell niche.	SULF2 SULF1	2.00e-05	4	64	2	20855470
Pubmed	Roles of heparan sulfate sulfation in dentinogenesis.	SULF2 SULF1	3.32e-05	5	64	2	22351753
Pubmed	Sulfatase modifying factor 1-mediated fibroblast growth factor signaling primes hematopoietic multilineage development.	SULF2 SULF1	3.32e-05	5	64	2	20643830
Pubmed	Basement membrane localization of Frem3 is independent of the Fras1/Frem1/Frem2 protein complex within the sublamina densa.	FRAS1 NID1	3.32e-05	5	64	2	17596926
Pubmed	Nidogen-1. Expression and ultrastructural localization during the onset of mesoderm formation in the early mouse embryo.	COL4A4 NID1	6.96e-05	7	64	2	10639489
Pubmed	Sulfatase 1 is an inhibitor of ductal morphogenesis with sexually dimorphic expression in the urogenital sinus.	SULF2 SULF1	6.96e-05	7	64	2	20410206
Pubmed	Hypoplastic basement membrane of the lens anlage in the inheritable lens aplastic mouse (lap mouse).	COL4A4 NID1	6.96e-05	7	64	2	10716744
Pubmed	The GSK-3β-FBXL21 Axis Contributes to Circadian TCAP Degradation and Skeletal Muscle Function.	CUL1 TCAP	6.96e-05	7	64	2	32937135
Pubmed	Mac-2 binding protein is a cell-adhesive protein of the extracellular matrix which self-assembles into ring-like structures and binds beta1 integrins, collagens and fibronectin.	COL5A1 NID1	6.96e-05	7	64	2	9501082
Pubmed	Redundant function of the heparan sulfate 6-O-endosulfatases Sulf1 and Sulf2 during skeletal development.	SULF2 SULF1	6.96e-05	7	64	2	18213582
Pubmed	HENA, heterogeneous network-based data set for Alzheimer's disease.	DST RANBP9 APBB1 DYNC1H1	7.30e-05	120	64	4	31413325
Pubmed	Fras1 deficiency results in cryptophthalmos, renal agenesis and blebbed phenotype in mice.	FRAS1 NID1	9.27e-05	8	64	2	12766770
Pubmed	Proteasome-dependent degradation of transcription factor activating enhancer-binding protein 4 (TFAP4) controls mitotic division.	CUL1 REST	9.27e-05	8	64	2	24500709
Pubmed	Developmental changes in seminiferous tubule extracellular matrix components of the mouse testis: alpha 3(IV) collagen chain expressed at the initiation of spermatogenesis.	COL4A4 NID1	1.19e-04	9	64	2	8562707
Pubmed	SULF1 and SULF2 regulate heparan sulfate-mediated GDNF signaling for esophageal innervation.	SULF2 SULF1	1.19e-04	9	64	2	17720696
Pubmed	Characterization of high affinity binding between laminin and the acute-phase protein, serum amyloid A.	COL4A4 NID1	1.19e-04	9	64	2	8995276
Pubmed	Ataxin-3 promotes genome integrity by stabilizing Chk1.	CUL1 DYNC1H1	1.19e-04	9	64	2	28180282
Pubmed	Interaction of Smads with collagen types I, III, and V.	COL5A1 SMAD1	1.49e-04	10	64	2	14559231
Pubmed	The extracellular matrix gene Frem1 is essential for the normal adhesion of the embryonic epidermis.	COL5A1 FRAS1	1.49e-04	10	64	2	15345741
Pubmed	Basement membrane distortions impair lung lobation and capillary organization in the mouse model for fraser syndrome.	FRAS1 NID1	1.49e-04	10	64	2	15623520
Pubmed	Collagen IV is essential for basement membrane stability but dispensable for initiation of its assembly during early development.	COL4A4 NID1	1.81e-04	11	64	2	14998921
Pubmed	Binding of mouse and human fibulin-2 to extracellular matrix ligands.	COL4A4 NID1	1.81e-04	11	64	2	7500359
Pubmed	Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.	CUL1 FRAS1 COL27A1 REST	1.82e-04	152	64	4	34299191
Pubmed	Dysregulated cell signalling and reduced satellite cell potential in ageing muscle.	SULF2 SULF1	2.17e-04	12	64	2	31647919
Pubmed	Matrilin-2 interacts with itself and with other extracellular matrix proteins.	COL4A4 NID1	2.17e-04	12	64	2	12180907
Pubmed	Sulfatase 2 Modulates Fate Change from Motor Neurons to Oligodendrocyte Precursor Cells through Coordinated Regulation of Shh Signaling with Sulfatase 1.	SULF2 SULF1	2.17e-04	12	64	2	28490013
Pubmed	Control of chromosome stability by the beta-TrCP-REST-Mad2 axis.	CUL1 REST	2.17e-04	12	64	2	18354482
Pubmed	Compound genetic ablation of nidogen 1 and 2 causes basement membrane defects and perinatal lethality in mice.	COL4A4 NID1	2.17e-04	12	64	2	16024816
Pubmed	Basal lamina molecules are concentrated in myogenic regions of the mouse limb bud.	COL4A4 NID1	2.57e-04	13	64	2	9833687
Pubmed	Furin, a transcriptional target of NKX2-5, has an essential role in heart development and function.	COL5A1 SMAD1	2.57e-04	13	64	2	30840660
Pubmed	Mesangial cells organize the glomerular capillaries by adhering to the G domain of laminin alpha5 in the glomerular basement membrane.	COL4A4 NID1	2.57e-04	13	64	2	12682087
Pubmed	Cytoplasmic plaque formation in hemidesmosome development is dependent on SoxF transcription factor function.	DST NID1	2.57e-04	13	64	2	22962592
Pubmed	IgD class switching is initiated by microbiota and limited to mucosa-associated lymphoid tissue in mice.	PLA2G4B TP53BP1	2.57e-04	13	64	2	28137874
Pubmed	Expression patterns of sulfatase genes in the developing mouse embryo.	SULF2 SULF1	2.57e-04	13	64	2	20503373
Pubmed	FOXD1 is required for 3D patterning of the kidney interstitial matrix.	COL4A4 COL5A1	2.57e-04	13	64	2	36335435
Pubmed	Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.	COL4A4 COL5A1 COL27A1 NID1	3.11e-04	175	64	4	28071719
Pubmed	Identification of Novel Nuclear Factor of Activated T Cell (NFAT)-associated Proteins in T Cells.	ZNF148 NFATC2 RANBP9 TP53BP1	3.32e-04	178	64	4	27637333
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	RLF ZNF12 ZNF142 ZNF473 TIMELESS ZNF227 ZNF768 JMJD1C TP53BP1	3.43e-04	1203	64	9	29180619
Pubmed	Defective glomerulogenesis in the absence of laminin alpha5 demonstrates a developmental role for the kidney glomerular basement membrane.	COL4A4 NID1	3.45e-04	15	64	2	10625553
Pubmed	New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.	WHRN FRAS1 DST NID1 TIMELESS USPL1	3.64e-04	513	64	6	25798074
Pubmed	O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.	ADAMTS18 CFP ADAMTSL2	3.65e-04	75	64	3	20637190
Pubmed	The type I BMP receptors, Bmpr1a and Acvr1, activate multiple signaling pathways to regulate lens formation.	NID1 SMAD1	3.93e-04	16	64	2	19733164
Pubmed	Spatially distinct functions of PAX6 and NKX2.2 during gliogenesis in the ventral spinal cord.	SULF2 SULF1	3.93e-04	16	64	2	19258013
Pubmed	Impairment of endothelial-mesenchymal transformation during atrioventricular cushion formation in Tmem100 null embryos.	NFATC2 SMAD1	3.93e-04	16	64	2	25318679
Pubmed	Identification of a novel cell-adhesive protein spatiotemporally expressed in the basement membrane of mouse developing hair follicle.	COL4A4 NID1	3.93e-04	16	64	2	15878328
Pubmed	Transcriptome-based systematic identification of extracellular matrix proteins.	COL4A4 FRAS1 NID1	4.25e-04	79	64	3	18757743
Pubmed	Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry.	NEU1 SPATA31A7 TP53BP1	4.41e-04	80	64	3	16094384
Pubmed	Identification of RanBP 9/10 as interacting partners for protein kinase C (PKC) gamma/delta and the D1 dopamine receptor: regulation of PKC-mediated receptor phosphorylation.	RANBP9 DYNC1H1	4.45e-04	17	64	2	20395553
Pubmed	Isolation and fine mapping of 16 novel human zinc finger-encoding cDNAs identify putative candidate genes for developmental and malignant disorders.	ZNF142 ZNF148	4.45e-04	17	64	2	7557990
Pubmed	Integrin beta1-mediated matrix assembly and signaling are critical for the normal development and function of the kidney glomerulus.	COL4A4 NID1	4.45e-04	17	64	2	18082680
Pubmed	An approach based on a genome-wide association study reveals candidate loci for narcolepsy.	CRADD NFATC2 SULF1 DYNC1H1	4.50e-04	193	64	4	20677014
Pubmed	TGF-β-activated kinase 1 (Tak1) mediates agonist-induced Smad activation and linker region phosphorylation in embryonic craniofacial neural crest-derived cells.	NFATC2 SMAD1	5.00e-04	18	64	2	23546880
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	RLF CFAP251 ZNF148 ADAMTS18 JMJD1C	5.41e-04	361	64	5	26167880
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	LDLRAP1 DST ZNF473 SULF1 RANBP9 APBB1 ZNF227 USPL1 DYNC1H1	5.52e-04	1285	64	9	35914814
Pubmed	Quantitative interactomics in primary T cells unveils TCR signal diversification extent and dynamics.	THEMIS NFATC2	6.20e-04	20	64	2	31591574
Pubmed	Genome-wide analysis of polymorphisms associated with cytokine responses in smallpox vaccine recipients.	COL4A4 THEMIS TIMELESS	6.43e-04	91	64	3	22610502
Cytoband	Ensembl 112 genes in cytogenetic band chr9q12	SPATA31A7 SPATA31A5	5.33e-05	8	64	2	chr9q12
Cytoband	9p13.1	SPATA31A1 SPATA31A3	5.18e-04	24	64	2	9p13.1
Cytoband	9q32	WHRN COL27A1	1.99e-03	47	64	2	9q32
Cytoband	Ensembl 112 genes in cytogenetic band chr9q32	WHRN COL27A1	2.24e-03	50	64	2	chr9q32
Cytoband	Ensembl 112 genes in cytogenetic band chr8q13	SULF1 MYBL1	5.10e-03	76	64	2	chr8q13
GeneFamily	Collagens	COL4A4 COL5A1 COL27A1	2.03e-04	46	45	3	490
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	RLF ZNF12 ZNF677 ZNF142 ZNF148 ZNF473 ZNF227 ZNF768	3.48e-04	718	45	8	28
GeneFamily	Sulfatases	SULF2 SULF1	9.04e-04	18	45	2	410
GeneFamily	GATA zinc finger domain containing\|Myb/SANT domain containing	TERB1 MYBL1	7.70e-03	53	45	2	532
ToppCell	COVID-19-kidney-Fibroblast-1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	COL4A4 COL5A1 CFAP251 GUCY1A2 SULF1 COL27A1 NID1 ADAMTSL2	2.78e-10	187	64	8	76bfe8c42430a230a8bdf299575c444fb7780f24
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A4 COL5A1 GUCY1A2 NFATC2 COL27A1 NID1 ADAMTSL2	1.39e-08	197	64	7	85a8f1d18e0dd1d31341f5131eecd217553bf042
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A4 COL5A1 GUCY1A2 NFATC2 COL27A1 NID1 ADAMTSL2	1.39e-08	197	64	7	e8e3ba791dfaa0fab35e0329a5e34376f9ee6143
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A4 COL5A1 GUCY1A2 NFATC2 COL27A1 NID1 ADAMTSL2	1.44e-08	198	64	7	a860246bcea847249a78fd2e86ed8e04371060db
ToppCell	COVID-19-COVID-19_Severe-Myeloid-cDC\|COVID-19_Severe / Disease, condition lineage and cell class	CUL1 RNASE6 SULF2 DST CFP UNC93B1 ACSF2	1.55e-08	200	64	7	e7b808d8ed65343a4345fafb03015fe4f7ce302f
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A4 COL5A1 CFAP251 GUCY1A2 NID1 ADAMTSL2	2.18e-07	178	64	6	d4ecb84e9b1f4ec49c519321156aa10f9bd34cce
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A4 COL5A1 GUCY1A2 SULF1 NID1 ADAMTSL2	3.31e-07	191	64	6	39092a0aff8097617820c59f5fea9ee2bb4f63a2
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A4 COL5A1 GUCY1A2 SULF1 NID1 ADAMTSL2	3.31e-07	191	64	6	ee5f1b1c59029c46cbb1a00935c03b9317bb9da9
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A4 COL5A1 GUCY1A2 COL27A1 NID1 ADAMTSL2	3.41e-07	192	64	6	9093a9e94a25682d109a7f6edc256a25a61103a0
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A4 COL5A1 GUCY1A2 COL27A1 NID1 ADAMTSL2	3.41e-07	192	64	6	9ed5d49621ec1aa01716dc369bba1450b5f015f5
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A4 COL5A1 GUCY1A2 SULF1 NID1 ADAMTSL2	3.62e-07	194	64	6	e03ba6caed59fa64d4d9b042593469d4a6a3dc10
ToppCell	COVID-19-kidney-Fibroblast-2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	COL4A4 COL5A1 GUCY1A2 SULF1 COL27A1 NID1	3.73e-07	195	64	6	3d62ce1c696f47d4d7eb0c5bb0eec2c24b122bb2
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A4 COL5A1 GUCY1A2 SULF1 NID1 ADAMTSL2	3.85e-07	196	64	6	3a6c942e2907aa07b5e12dbf9019d18f7bfca507
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A4 COL5A1 GUCY1A2 SULF1 NID1 ADAMTSL2	3.85e-07	196	64	6	bba88e91cd3e3a6f5a9b443e3a4da33c5b455e70
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A4 COL5A1 GUCY1A2 SULF1 NID1 ADAMTSL2	3.96e-07	197	64	6	09946ee8dfb15a2a32da06e5b331f3277ee934f4
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A4 COL5A1 GUCY1A2 SULF1 NID1 ADAMTSL2	3.96e-07	197	64	6	ae0435f4b4a9cdedb1c201fc56921048390097bf
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A4 COL5A1 GUCY1A2 SULF1 NID1 ADAMTSL2	3.96e-07	197	64	6	37f6b6f2809b952382eaebb642b0aad6371f4251
ToppCell	PBMC-Severe-Myeloid-cDC\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RNASE6 SULF2 DST CFP UNC93B1 ACSF2	3.96e-07	197	64	6	22e4ffb5de483eaf78f14badf3d08db898e3b3dd
ToppCell	PBMC-Severe-Myeloid-cDC\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	RNASE6 SULF2 DST CFP UNC93B1 ACSF2	3.96e-07	197	64	6	346974c6c5809a3fe88cbf067e2d64c340310a31
ToppCell	PBMC-Severe-Myeloid-cDC-cDC\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RNASE6 SULF2 DST CFP UNC93B1 ACSF2	3.96e-07	197	64	6	1ae45c1ec3b3f88e0c1f99de58c58b1ec1b968ee
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL5A1 GUCY1A2 NFATC2 COL27A1 NID1 ADAMTSL2	3.96e-07	197	64	6	9b480f9c799a244bfee64487abd8a1bf07c9a3a2
ToppCell	COVID-19_Severe-Myeloid-cDC\|COVID-19_Severe / Disease group, lineage and cell class	RNASE6 SULF2 DST CFP UNC93B1 ACSF2	3.96e-07	197	64	6	843b0f1cc26864ee635df7938c77552ee06fe00b
ToppCell	PBMC-Severe-Myeloid-cDC-cDC\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	RNASE6 SULF2 DST CFP UNC93B1 ACSF2	3.96e-07	197	64	6	f78f44dcd7855c96f148678c1f416075aef71b4e
ToppCell	COVID-19-kidney-Fibroblast-1\|kidney / Disease (COVID-19 only), tissue and cell type	COL5A1 DST GUCY1A2 SULF1 NID1 ADAMTSL2	4.20e-07	199	64	6	9503646ff1ad248181146ce767e9d12e882ec3bd
ToppCell	COVID-19-COVID-19_Mild-Myeloid-cDC\|COVID-19_Mild / Disease, condition lineage and cell class	RNASE6 SULF2 DST CFP UNC93B1 ACSF2	4.33e-07	200	64	6	b8f52e65813d331c49cdd5f354fdfec6fc8c339e
ToppCell	severe-cDC\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	RNASE6 SULF2 DST CFP UNC93B1 MAML3	4.33e-07	200	64	6	26e04ea276dbca5cde48335c401269c7123b54d2
ToppCell	mild-cDC\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	RNASE6 SULF2 DST CFP ACSF2 MAML3	4.33e-07	200	64	6	d6409ee5b9067be3dd2f852825e09151b5b22d7c
ToppCell	droplet-Lung-LUNG-1m-Myeloid-Myeloid_Dendritic_Type_1\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RNASE6 TMED6 NFATC2 CFP UNC93B1	4.49e-06	169	64	5	735655e75511c5c41aca667909e8bb52a0ad7fc6
ToppCell	Healthy_donor-MAIT\|World / disease group, cell group and cell class (v2)	WHRN THEMIS SESN1 ADAMTSL2 MYBL1	4.89e-06	172	64	5	6524eb2be1c78700ad367e62624a4d7eb48b54f0
ToppCell	PND07-28-samps-Myeloid-Macrophage-CD163+_Macrophage\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	NFATC2 AOAH CFP UNC93B1 SESN1	4.89e-06	172	64	5	9a659442dc41bd2a4361a7e38a7ee37a39781667
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A4 COL5A1 NFATC2 SULF1 ADAMTSL2	5.47e-06	176	64	5	9bc87cd5cda2372e1bce94c9dfd408eb1dfd8d0c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A4 COL5A1 NFATC2 SULF1 ADAMTSL2	5.47e-06	176	64	5	3f8274a7ab67f9f8a8923193763a5543cfe4defa
ToppCell	facs-Lung-24m-Hematologic-myeloid-myeloid_dendritic_cell-myeloid_dendritic_type_1\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RNASE6 SULF2 NFATC2 CFP UNC93B1	5.47e-06	176	64	5	a85ad8b4815fde72edd5c900e882a0bc04033ea8
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GALNT15 COL4A4 FRAS1 SULF2 SULF1	6.27e-06	181	64	5	330d4322f4c4373f706273c1f4e218b59051b7fd
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GALNT15 COL4A4 FRAS1 SULF2 SULF1	6.27e-06	181	64	5	3f4d5d79c1286614514b0e8134079d6128a2a23e
ToppCell	facs-Lung-EPCAM-24m-Myeloid-myeloid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RNASE6 NFATC2 CFP TIMELESS UNC93B1	6.44e-06	182	64	5	9465238ac806fce46dfe1a141e83893f23eb4afb
ToppCell	Healthy_donor-MAIT\|Healthy_donor / disease group, cell group and cell class (v2)	WHRN THEMIS SESN1 ADAMTSL2 MYBL1	6.44e-06	182	64	5	ac7c83464487ecde3df6804a99551307bd768f21
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A4 COL5A1 GUCY1A2 NID1 ADAMTSL2	6.79e-06	184	64	5	c5436a8e45f471b8d1301abbe9c7879204537f52
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell-D122\|Adult / Lineage, Cell type, age group and donor	GALNT15 COL5A1 SULF1 NID1 ADAMTSL2	6.79e-06	184	64	5	2b7e6f91e11c228f0521e099886867d9e998e78d
ToppCell	10x5'v1-week_12-13-Lymphocytic_NK-T_NK-CD56_bright_NK\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	COL4A4 NFATC2 APBB1 SESN1 MYBL1	6.97e-06	185	64	5	593eceb3dfcc662c892a840ba29ab687c6886c01
ToppCell	LA-01._Fibroblast_I\|World / Chamber and Cluster_Paper	GALNT15 COL4A4 COL5A1 SULF1 NID1	7.35e-06	187	64	5	4ea486991f66c29728d127171a07b81404ec0b78
ToppCell	Control-Fibroblasts-Alveolar_FB\|Control / group, cell type (main and fine annotations)	COL5A1 FRAS1 DST NID1 ADAMTSL2	7.35e-06	187	64	5	92d468dde81125d51daf7abd4703741abe1ab91c
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_8\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	NEU1 RNASE6 DST CFP UNC93B1	7.54e-06	188	64	5	8431991e68b8e9c5eb72212460f6da679ea3b85a
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_8\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	NEU1 RNASE6 DST CFP UNC93B1	7.54e-06	188	64	5	d8f10b3ad11bc99a63f44560e39791085256e5c8
ToppCell	Control-Fibroblasts-Adventitial_FB\|Control / group, cell type (main and fine annotations)	GALNT15 COL5A1 NFATC2 SULF1 NID1	7.54e-06	188	64	5	706a26c372add839d947749f0521a0e1f5c9b0ec
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A4 COL5A1 GUCY1A2 NID1 ADAMTSL2	7.74e-06	189	64	5	71397e993a77d70b2eeede240bdfc7660b558987
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A4 COL5A1 GUCY1A2 NID1 ADAMTSL2	7.74e-06	189	64	5	4eea4759520c312bd17a681034d8074e47093d2b
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL5A1 DST GUCY1A2 SULF1 NID1	7.94e-06	190	64	5	2e88e366d377d74deb53a4ea870973ce5c6532e8
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL5A1 DST GUCY1A2 SULF1 NID1	7.94e-06	190	64	5	0028f886c789ba238c031eae5d96acaed4af8c25
ToppCell	Control-Fibroblasts\|Control / group, cell type (main and fine annotations)	COL5A1 DST GUCY1A2 SULF1 NID1	7.94e-06	190	64	5	3a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A4 COL5A1 GUCY1A2 NID1 ADAMTSL2	8.14e-06	191	64	5	a6c57627077fa980b7ec1d3894b5f31bfb11b738
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL5A1 DST COL27A1 NID1 ADAMTSL2	8.14e-06	191	64	5	806b94f567ea09a9f443cd4091e70cdb1253ac08
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A4 COL5A1 GUCY1A2 NID1 ADAMTSL2	8.14e-06	191	64	5	8f6d592edc32fdb901af30501d4360512334e8c2
ToppCell	PBMC-Severe-Myeloid-cDC-cDC-cDC_5\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	RNASE6 SULF2 DST CFP UNC93B1	8.14e-06	191	64	5	92c5a26b90a55831039220341d863cf2940f3c9b
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A4 COL5A1 GUCY1A2 NID1 ADAMTSL2	8.35e-06	192	64	5	bc84b9ce01b4d826a682842ab8a395dac9b91183
ToppCell	facs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A4 COL5A1 SULF1 NID1 ADAMTSL2	8.35e-06	192	64	5	671d4e1eee5aba03c43dbc98f4b51ce42b3df5d5
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL5A1 GUCY1A2 SULF1 NID1 ADAMTSL2	8.35e-06	192	64	5	5105e4b577408b4e1a62d0a44c23c2b830ccad88
ToppCell	facs-Lung-nan-3m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GALNT15 COL5A1 SULF2 SULF1 NID1	8.35e-06	192	64	5	a2c31390da4962bda9a936470b0b68fa1f5d47d1
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL5A1 GUCY1A2 SULF1 NID1 ADAMTSL2	8.35e-06	192	64	5	d3c1ad4667a1e223a83ca0fcd5991a0b96f1199a
ToppCell	facs-Lung-nan-3m-Mesenchymal-adventitial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GALNT15 COL5A1 SULF2 SULF1 NID1	8.35e-06	192	64	5	eeab1cef7c36ae824381952c5b2c982368c379fd
ToppCell	PBMC-Severe-Myeloid-cDC-cDC-cDC_5\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RNASE6 SULF2 DST CFP UNC93B1	8.35e-06	192	64	5	6184163dbfca882824cb266bb9030d9f79e3acb0
ToppCell	facs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A4 COL5A1 SULF1 NID1 ADAMTSL2	8.35e-06	192	64	5	840a34c1b82d218be999ab5e1bcafd6370d7a4b1
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell\|Adult / Lineage, Cell type, age group and donor	GALNT15 COL5A1 GUCY1A2 SULF1 NID1	8.35e-06	192	64	5	d21f0f577156f17c899b08871046a26b88aea011
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A4 COL5A1 GUCY1A2 NID1 ADAMTSL2	8.35e-06	192	64	5	0ab1176cfbb0de8dd1f22c6e2c41265cf6c10ee1
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL5A1 GUCY1A2 SULF1 NID1 ADAMTSL2	8.56e-06	193	64	5	dc8e62df6121ee99b156aca6b1b3ae555739b6f2
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	COL5A1 DST COL27A1 NID1 ADAMTSL2	8.56e-06	193	64	5	b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCell	LV-01._Fibroblast_I\|LV / Chamber and Cluster_Paper	GALNT15 COL4A4 COL5A1 SULF1 NID1	8.56e-06	193	64	5	dc17f3b9758936d428cf17f77a1ce6d4c479b165
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL5A1 GUCY1A2 SULF1 NID1 ADAMTSL2	8.56e-06	193	64	5	e2ee077fd381bd906e6b4329f22e7d106e422a7f
ToppCell	PBMC-Control-Myeloid-cDC-cDC-cDC_3\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RNASE6 SULF2 DST CFP ACSF2	8.78e-06	194	64	5	b16ed97eb6b7b7a220e943474c0d85c141b6e3a5
ToppCell	PBMC-Control-Myeloid-cDC-cDC-cDC_3\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	RNASE6 SULF2 DST CFP ACSF2	8.78e-06	194	64	5	2210f0755882d8f04edb4c109fb17c3f9149f6f7
ToppCell	10x5'v1-week_12-13-Lymphocytic_NK\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	COL4A4 NFATC2 APBB1 SESN1 MYBL1	8.78e-06	194	64	5	5afe7f48d3383f3dac18765f97999c8b6936dc1b
ToppCell	10x5'v1-week_12-13-Lymphocytic_NK-T_NK\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	COL4A4 NFATC2 APBB1 SESN1 MYBL1	8.78e-06	194	64	5	ec7e0ca6c9a2f63938e06ee771da09eff14fc3b5
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL5A1 GUCY1A2 SULF1 NID1 ADAMTSL2	8.78e-06	194	64	5	29f83cdd63314fff41258937d70b881a5503bfcc
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	COL5A1 FRAS1 DST GUCY1A2 ADAMTSL2	8.78e-06	194	64	5	35f132cc38ac133be01834ed0946188aa0757eb4
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL5A1 GUCY1A2 SULF1 NID1 ADAMTSL2	8.78e-06	194	64	5	d3db241ea316bbcde6d16618193b474591ad5ce4
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL5A1 GUCY1A2 SULF1 NID1 ADAMTSL2	9.00e-06	195	64	5	49c99553629cdd83ee56a2e508d5bc8d34b8507b
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A4 GUCY1A2 SULF1 NID1 ADAMTSL2	9.00e-06	195	64	5	803f714d91f2d97ecbee8c15a5139fd9310f66c7
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A4 COL5A1 GUCY1A2 NID1 ADAMTSL2	9.00e-06	195	64	5	cad6563cc51d212554152c727fc2c249c6a07e4d
ToppCell	LA-02._Fibroblast_II\|World / Chamber and Cluster_Paper	GALNT15 COL4A4 COL5A1 SULF1 NID1	9.00e-06	195	64	5	a78b605b49acd8c9d68716266ca269dafcd910b9
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL5A1 GUCY1A2 SULF1 NID1 ADAMTSL2	9.00e-06	195	64	5	dd281a249854800f737dc22e0f375f66dfb5cf5f
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A4 COL5A1 GUCY1A2 SULF1 ADAMTSL2	9.00e-06	195	64	5	3c3703f092b6fc1b7333426fb5e2823bfb74bb57
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A4 COL5A1 GUCY1A2 NID1 ADAMTSL2	9.00e-06	195	64	5	783bfa8110161cbd6def50ce849cae676c39c458
ToppCell	PBMC-Severe-Myeloid-cDC-cDC-cDC_9\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CUL1 RNASE6 DST CFP UNC93B1	9.00e-06	195	64	5	dd28c63b53f2a97e3fac127294a465870dc371b3
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A4 GUCY1A2 SULF1 NID1 ADAMTSL2	9.00e-06	195	64	5	4f70157d42a16ff0259bc24a62803c4df4285c44
ToppCell	PBMC-Severe-Myeloid-cDC-cDC-cDC_9\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CUL1 RNASE6 DST CFP UNC93B1	9.00e-06	195	64	5	d6ff38535898f90be6719cd5152291f2f4f8a746
ToppCell	PBMC-Control-Myeloid-cDC\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	RNASE6 SULF2 DST CFP ACSF2	9.23e-06	196	64	5	e1f763fa9c11bf5f4d80e79f70f9485724ac23fe
ToppCell	Control-Myeloid-cDC\|Control / Disease group, lineage and cell class	RNASE6 SULF2 DST CFP ACSF2	9.23e-06	196	64	5	85d92bc226cc28384c30991cc4ebb02ec2e3ec99
ToppCell	PBMC-Control-Myeloid-cDC-cDC\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RNASE6 SULF2 DST CFP ACSF2	9.23e-06	196	64	5	553c22c7d48f3b4f6f2b2f10d6e668c5ebb09e8c
ToppCell	COVID-19_Moderate-cDC\|World / disease group, cell group and cell class	CUL1 RNASE6 DST CFP UNC93B1	9.23e-06	196	64	5	92a236adf386f05d020b1954bbdc5bd32346cbf0
ToppCell	PBMC-Control-Myeloid-cDC\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RNASE6 SULF2 DST CFP ACSF2	9.23e-06	196	64	5	d376168e15ec1cf618723259966c76be3698b9b0
ToppCell	PBMC-Control-Myeloid-cDC-cDC\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	RNASE6 SULF2 DST CFP ACSF2	9.23e-06	196	64	5	4a9095ba3f6709f88f32bf09184553f4bd211f43
ToppCell	PBMC-Mild-Myeloid-cDC-cDC\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	RNASE6 SULF2 DST CFP UNC93B1	9.46e-06	197	64	5	9162ede5572326c00ede0769fe7f4e0dd14d2340
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Dendritic\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RNASE6 SULF2 DST CFP UNC93B1	9.46e-06	197	64	5	89fe4885efc8db142c0dc0506840ae8aceba9ef9
ToppCell	PBMC-Mild-Myeloid-cDC\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RNASE6 SULF2 DST CFP UNC93B1	9.46e-06	197	64	5	021c9c48375259b808e1f36a029c4fe6971c00eb
ToppCell	PBMC-Mild-Myeloid-cDC\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	RNASE6 SULF2 DST CFP UNC93B1	9.46e-06	197	64	5	18df0e447bcea2a405a357563f87bacc57466227
ToppCell	PBMC-Mild-Myeloid-cDC-cDC\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RNASE6 SULF2 DST CFP UNC93B1	9.46e-06	197	64	5	0460b6907743a354792b5bc40bff01aac7c41684
ToppCell	COVID-19_Mild-Myeloid-cDC\|COVID-19_Mild / Disease group, lineage and cell class	RNASE6 SULF2 DST CFP UNC93B1	9.46e-06	197	64	5	2901904b8a791fac2668fd737eff7e7144378db4
ToppCell	Monocytes-cDCs\|World / Immune cells in Kidney/Urine in Lupus Nephritis	RNASE6 SULF2 DST CFP MAML3	9.46e-06	197	64	5	3388c104af4c6a05988e102627e0c5e34d9dcc45
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL5A1 GUCY1A2 SULF1 NID1 ADAMTSL2	9.46e-06	197	64	5	4cf4e9553397cd8dee883dbec24f41bec41aff99
ToppCell	Healthy_donor-cDC\|World / disease group, cell group and cell class (v2)	RNASE6 SULF2 DST CFP ACSF2	9.46e-06	197	64	5	a545fe3a80cd721bf01115bbb645753840ec9f40
Disease	coagulation factor XA measurement	WHRN COL27A1	2.21e-04	11	60	2	EFO_0020266
Disease	liver volume	JMJD1C TP53BP1	4.20e-04	15	60	2	EFO_0600048
Disease	nicotine dependence symptom count, depressive symptom measurement	GALNT15 SULF2 THEMIS	4.86e-04	75	60	3	EFO_0007006, EFO_0009262
Disease	maximal midexpiratory flow rate	GALNT15 MYO16	7.55e-04	20	60	2	EFO_0004313
Disease	forced expiratory volume	NEU1 DST CRADD SULF1 REST SLC2A12 JMJD1C	1.07e-03	789	60	7	EFO_0004314
Disease	Adenoid Cystic Carcinoma	JMJD1C MAML3 MYBL1	1.12e-03	100	60	3	C0010606
Disease	tyrosine measurement	COL5A1 CFAP251 JMJD1C	1.26e-03	104	60	3	EFO_0005058
Disease	hair shape measurement	FRAS1 PRSS53	1.38e-03	27	60	2	EFO_0007824
Disease	glucocorticoid receptor gene expression measurement	WHRN GUCY1A2	1.38e-03	27	60	2	EFO_0600079
Disease	urate measurement, bone density	COL5A1 FRAS1 SULF1 AOAH SLC2A12 MYO16	1.59e-03	619	60	6	EFO_0003923, EFO_0004531
Disease	migraine disorder, glucose measurement	SESN1 JMJD1C	1.82e-03	31	60	2	EFO_0004468, MONDO_0005277

Protein segments in the cluster

Peptide	Gene	Start	Entry
NIHQVCHYAQRNDRS	COL4A4	1526	P53420
HLDQLQYNQQFLSCH	ACSF2	241	Q96CM8
NCIRQLSYHKNNLHD	APBB1	396	O00213
LINHHADQSLNSFCQ	ADAMTS18	356	Q8TE60
NQYHLQGHANIISCL	CFAP251	291	Q8TBY9
YCHSNKHQSSNLNVP	RANBP9	526	Q96S59
HLLQTQNQGYTHFCR	NUDT8	146	Q8WV74
NFTHICRSHNSINQS	SLC2A12	371	Q8TD20
YIAQSQHNQSLECHA	LDLRAP1	131	Q5SW96
RNHCNHRDYQNISRN	AOAH	326	P28039
TNQQLRCGSHQEFQH	NFATC2	816	Q13469
QCSYVASNQHEVTRH	REST	336	Q13127
HNTGSICLRCQNAHY	FRAS1	821	Q86XX4
RHHVNCENRYQQAQV	MAML3	86	Q96JK9
SSEQNHQPCSHAAYN	IRF1-AS1	106	Q8N8D9
HQPCSHAAYNQVERQ	IRF1-AS1	111	Q8N8D9
LHLNNLCAHRYLNQT	MYO16	611	Q9Y6X6
NHVQHLQSACASSHQ	DST	4836	Q03001
ANQNVNAVHSHYTRA	JMJD1C	266	Q15652
TCSNLDLNNHHSLYV	GPR137C	411	Q8N3F9
CSDSRQQQYLQHTSR	GALNT15	536	Q8N3T1
SYNTDSRQTCANNRH	NID1	381	P14543
QCVSFNSHVYNGRTH	ADAMTSL2	116	Q86TH1
HLTHYNVCNNQEQLL	PLA2G4B	751	P0C869
AGQQQDIRHCYSIQH	CFP	361	P27918
LAAQRHYCSQNQIEH	OR56B2P	171	Q8NGI1
HCVNNTYRSAQHSQA	KLHL22	21	Q53GT1
NYCTSVHQSNQARGA	CUL1	51	Q13616
YRCKANHPHNVQSQV	CRADD	146	P78560
ASAHQNVTYHCYQSV	COL5A1	1736	P20908
VTQVAHNYCTHLRKQ	COL27A1	221	Q8IZC6
RFQFHNTSICVVNSH	INPP5B	466	P32019
SCVFVHQTLHQANAR	DYNC1H1	3146	Q14204
IASHLQNRSDFQCQH	MYBL1	61	P10243
HNISNRCSYADHSNK	GUCY1A2	131	P33402
ARHQCSYLVNLHVND	SESN1	126	Q9Y6P5
CAFNSSVQQDHLSRH	SPATA31A7	291	Q8IWB4
VINARNQNNYHCHCR	NEU1	276	Q99519
NQNNYHCHCRIVLRS	NEU1	281	Q99519
NFTRQRLLDHCNSNH	RNF138	166	Q8WVD3
QRHETYHQQGQCQVL	TCAP	46	O15273
SGINNYTQHCKHQNT	RNASE6	51	Q93091
EQFTHCLNAYHARRN	WHRN	56	Q9P202
SSIFVQSRNCNYHHG	SMAD1	351	Q15797
CAFNSSVQQDHLSRH	SPATA31A3	291	Q5VYP0
TCNCIYNQLHQRHLS	PRSS53	186	Q2L4Q9
SCAVARNHQTHSFNL	THEMIS	151	Q8N1K5
LRSYQQNSAHTNHCI	TIMELESS	711	Q9UNS1
QNTHLRQDHNYCSPT	USPL1	1016	Q5W0Q7
NHTLYNVQSCGTNSH	UNC93B1	251	Q9H1C4
TQHAVQVFNSYIQCH	XPO4	426	Q9C0E2
CGQIFTHRSNYSQHV	RLF	1451	Q13129
CAFNSSVQQDHLSRH	SPATA31A1	291	Q5TZJ5
CAFNSSVQQDHLSRH	SPATA31A5	291	Q5VU36
CYSQNSSLRSHQRVH	ZNF768	381	Q9H5H4
YQLCLSNQHNHFGSV	TMED6	116	Q8WW62
VHDSCHANQLQNYRN	TP53BP1	1831	Q12888
HNQAIQYLQQAHSVC	TTC23L	271	Q6PF05
NQCSNLTRHQRVHTG	ZNF677	301	Q86XU0
FSQSSNFQCHQRVHT	ZNF227	361	Q86WZ6
FCQNSALNRHQRTHT	ZNF12	586	P17014
CNAAFRTNYHLQRHV	ZNF148	176	Q9UQR1
YQSRHKQAVLSHENC	ZNF142	551	P52746
HNHNVYTNNENCSSP	SULF1	101	Q8IWU6
HSICQQNSNASVYFR	TERB1	41	Q8NA31
VHNHNTYTNNENCSS	SULF2	101	Q8IWU5
QHLRVHTQETLYQCQ	ZNF473	831	Q8WTR7
SLSRHQRVHNKQQYC	ZNF473	856	Q8WTR7
YCQILKQLTHNSNRH	MYO7B	1711	Q6PIF6