Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ATP hydrolysis activity	ABCC3 ABCA1 ABCF3 KIF27 ABCA12 EIF4A3 SRPRA CCT2 MORC4 ABCA8 MMAA CHD5 NAV1 DYNC1H1	5.42e-08	441	102	14	GO:0016887
GeneOntologyMolecularFunction	ATP-dependent activity	ABCC3 ABCA1 ABCF3 KIF27 EP400 ABCA12 EIF4A3 SRPRA CCT2 MORC4 ABCA8 MMAA CHD5 NAV1 DYNC1H1	5.16e-07	614	102	15	GO:0140657
GeneOntologyMolecularFunction	ribonucleoside triphosphate phosphatase activity	ABCC3 ABCA1 ABCF3 KIF27 ABCA12 EIF4A3 SRPRA CCT2 MORC4 ABCA8 MMAA CHD5 NAV1 DYNC1H1	3.93e-05	775	102	14	GO:0017111
GeneOntologyMolecularFunction	methylated histone binding	PHF8 MORC4 PWWP2A CHD5 CDYL	7.91e-05	86	102	5	GO:0035064
GeneOntologyMolecularFunction	methylation-dependent protein binding	PHF8 MORC4 PWWP2A CHD5 CDYL	8.82e-05	88	102	5	GO:0140034
GeneOntologyMolecularFunction	pyrophosphatase activity	ABCC3 ABCA1 ABCF3 KIF27 ABCA12 EIF4A3 SRPRA CCT2 MORC4 ABCA8 MMAA CHD5 NAV1 DYNC1H1	9.19e-05	839	102	14	GO:0016462
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	ABCC3 ABCA1 ABCF3 KIF27 ABCA12 EIF4A3 SRPRA CCT2 MORC4 ABCA8 MMAA CHD5 NAV1 DYNC1H1	9.31e-05	840	102	14	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	ABCC3 ABCA1 ABCF3 KIF27 ABCA12 EIF4A3 SRPRA CCT2 MORC4 ABCA8 MMAA CHD5 NAV1 DYNC1H1	9.31e-05	840	102	14	GO:0016818
GeneOntologyMolecularFunction	ABC-type transporter activity	ABCC3 ABCA1 ABCA12 ABCA8	1.14e-04	49	102	4	GO:0140359
GeneOntologyMolecularFunction	modification-dependent protein binding	PHF8 MORC4 PWWP2A YEATS2 CHD5 CDYL	6.63e-04	206	102	6	GO:0140030
GeneOntologyMolecularFunction	ATPase-coupled lipid transmembrane transporter activity	ABCC3 ABCA12	9.09e-04	9	102	2	GO:0034040
Domain	AAA+_ATPase	ABCC3 ABCA1 ABCF3 ABCA12 SRPRA ABCA8 MMAA NAV1 DYNC1H1	7.85e-08	144	100	9	IPR003593
Domain	AAA	ABCC3 ABCA1 ABCF3 ABCA12 SRPRA ABCA8 MMAA NAV1 DYNC1H1	7.85e-08	144	100	9	SM00382
Domain	P-loop_NTPase	ABCC3 ABCA1 ABCF3 KIF27 EP400 ABCA12 EIF4A3 MAGI3 DAPK1 SRPRA ABCA8 NLRC4 MMAA CHD5 NAV1 MYO18B GIMAP6 DYNC1H1	5.14e-07	848	100	18	IPR027417
Domain	ABC_tran	ABCC3 ABCA1 ABCF3 ABCA12 ABCA8	5.67e-06	48	100	5	PF00005
Domain	ABC_TRANSPORTER_2	ABCC3 ABCA1 ABCF3 ABCA12 ABCA8	5.67e-06	48	100	5	PS50893
Domain	ABC_TRANSPORTER_1	ABCC3 ABCA1 ABCF3 ABCA12 ABCA8	6.29e-06	49	100	5	PS00211
Domain	ABC_transporter-like	ABCC3 ABCA1 ABCF3 ABCA12 ABCA8	6.96e-06	50	100	5	IPR003439
Domain	SMK-1	PPP4R3A PPP4R3B	2.84e-05	2	100	2	PF04802
Domain	DUF625	PPP4R3A PPP4R3B	2.84e-05	2	100	2	IPR006887
Domain	ABC_A	ABCA1 ABCA12 ABCA8	3.16e-05	12	100	3	IPR026082
Domain	-	ABCC3 ABCA1 ABCF3 EP400 ABCA12 EIF4A3 SRPRA ABCA8 NLRC4 MMAA CHD5 NAV1 GIMAP6 DYNC1H1	4.26e-05	746	100	14	3.40.50.300
Domain	ABC_transporter_CS	ABCC3 ABCA1 ABCF3 ABCA12	7.41e-05	42	100	4	IPR017871
Domain	PDZ	ARHGEF12 MAGI3 CYTIP GRID2IP MAST4	9.68e-04	141	100	5	PF00595
Domain	PDZ	ARHGEF12 MAGI3 CYTIP GRID2IP MAST4	1.20e-03	148	100	5	SM00228
Domain	-	ARHGEF12 MAGI3 CYTIP GRID2IP MAST4	1.28e-03	150	100	5	2.30.42.10
Domain	PDZ	ARHGEF12 MAGI3 CYTIP GRID2IP MAST4	1.31e-03	151	100	5	PS50106
Domain	PDZ	ARHGEF12 MAGI3 CYTIP GRID2IP MAST4	1.35e-03	152	100	5	IPR001478
Domain	WH1	PPP4R3A PPP4R3B	2.13e-03	13	100	2	PS50229
Domain	ARM-type_fold	INTS7 PDCD4 RYR3 PPP4R3A PPP4R3B NF1 ELMO2	2.31e-03	339	100	7	IPR016024
Domain	Crotonase_core_superfam	ECHDC1 CDYL	3.66e-03	17	100	2	IPR001753
Domain	ECH_1	ECHDC1 CDYL	3.66e-03	17	100	2	PF00378
Domain	-	ECHDC1 CDYL	5.58e-03	21	100	2	3.90.226.10
Domain	ClpP/crotonase-like_dom	ECHDC1 CDYL	5.58e-03	21	100	2	IPR029045
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	ZBTB16 HIVEP2 EMC1 MAGI3 DENND4C MYLK2 TRAK1 NHSL1 HAUS8 NF1 MAST4 ELMO2 NAV1 FOXO4 WNK3 MAP3K2	5.23e-09	861	103	16	36931259
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	CYC1 NPPB WARS1 HIRIP3 EP400 INTS7 EIF4A3 ANXA4 VTI1A PCNX4 DYNC1H1 HCLS1	2.49e-06	754	103	12	35906200
Pubmed	BioID identifies novel c-MYC interacting partners in cultured cells and xenograft tumors.	SIN3B ATXN7L2 EP400 PPP4R3A YEATS2 CFDP1	3.08e-06	134	103	6	25452129
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	ARHGEF12 DENND4C TRAK1 NHSL1 KIDINS220 MAST4 FBXO42	3.11e-06	209	103	7	36779422
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	EP400 ARHGEF12 GPATCH8 PHF8 TRAK1 YEATS2 KIDINS220 NAV1 DYNC1H1	3.59e-06	407	103	9	12693553
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	CYC1 WARS1 ARHGEF12 POR DAPK1 CCT2 ALG2 NHSL1 FBXL16 KIDINS220 NF1 SLC25A12 NRXN2 NAV1 USP4 DYNC1H1	4.76e-06	1431	103	16	37142655
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	SIN3B ATXN7L2 HIRIP3 EP400 INTS7 EIF4A3 SRPRA GPATCH8 PHF8 PWWP2A YEATS2 TINF2 USP42 CDYL CUX1	6.34e-06	1294	103	15	30804502
Pubmed	MicroRNA-499-5p promotes cellular invasion and tumor metastasis in colorectal cancer by targeting FOXO4 and PDCD4.	PDCD4 FOXO4	8.69e-06	2	103	2	21934092
Pubmed	Loss of SMEK, a novel, conserved protein, suppresses MEK1 null cell polarity, chemotaxis, and gene expression defects.	PPP4R3A PPP4R3B	8.69e-06	2	103	2	16107728
Pubmed	Neurofibromin interacts with the cytoplasmic Dynein Heavy Chain 1 in melanosomes of human melanocytes.	NF1 DYNC1H1	8.69e-06	2	103	2	23583712
Pubmed	FAT1 acts as an upstream regulator of oncogenic and inflammatory pathways, via PDCD4, in glioma cells.	PDCD4 FAT1	8.69e-06	2	103	2	22986533
Pubmed	The Promyelocytic Leukemia Zinc Finger (PLZF ) gene is a novel transcriptional target of the CCAAT-Displacement-protein (CUX1) repressor.	ZBTB16 CUX1	8.69e-06	2	103	2	20945532
Pubmed	Genes of cholesterol metabolism in human atheroma: overexpression of perilipin and genes promoting cholesterol storage and repression of ABCA1 expression.	ABCA1 PLIN1	8.69e-06	2	103	2	15961705
Pubmed	MEKK2 mediates aberrant ERK activation in neurofibromatosis type I.	NF1 MAP3K2	8.69e-06	2	103	2	33177525
Pubmed	Charcot-Marie-Tooth Hereditary Neuropathy Overview	WARS1 DRP2 JPH1 DYNC1H1	1.28e-05	48	103	4	20301532
Pubmed	A novel, evolutionarily conserved protein phosphatase complex involved in cisplatin sensitivity.	CCT2 PPP4R3A PPP4R3B	1.99e-05	18	103	3	16085932
Pubmed	USP7 Regulates Cytokinesis through FBXO38 and KIF20B.	EP400 GPATCH8 MORC4 YEATS2 CUX1	2.55e-05	116	103	5	30804394
Pubmed	STAT1 mediated downregulation of the tumor suppressor gene PDCD4, is driven by the atypical cadherin FAT1, in glioblastoma.	PDCD4 FAT1	2.60e-05	3	103	2	38640981
Pubmed	Crystal structures of Delta1-piperideine-2-carboxylate/Delta1-pyrroline-2-carboxylate reductase belonging to a new family of NAD(P)H-dependent oxidoreductases: conformational change, substrate recognition, and stereochemistry of the reaction.	ABCA1 ARHGEF12	2.60e-05	3	103	2	16192274
Pubmed	NF1 regulates apoptosis in ovarian cancer cells by targeting MCL1 via miR-142-5p.	MCL1 NF1	2.60e-05	3	103	2	30543142
Pubmed	Binding of PDZ-RhoGEF to ATP-binding cassette transporter A1 (ABCA1) induces cholesterol efflux through RhoA activation and prevention of transporter degradation.	ABCA1 ARHGEF12	2.60e-05	3	103	2	20348106
Pubmed	Autism-associated familial microdeletion of Xp11.22.	PHF8 WNK3	2.60e-05	3	103	2	18498374
Pubmed	PP4R4/KIAA1622 forms a novel stable cytosolic complex with phosphoprotein phosphatase 4.	CCT2 PPP4R3A PPP4R3B	2.77e-05	20	103	3	18715871
Pubmed	Quantitative interaction proteomics and genome-wide profiling of epigenetic histone marks and their readers.	SIN3B ATXN7L2 PHF8 YEATS2 CDYL	3.52e-05	124	103	5	20850016
Pubmed	Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database.	ABCC3 ABCF3 ABCA12	3.73e-05	22	103	3	8894702
Pubmed	Substrate trapping proteomics reveals targets of the βTrCP2/FBXW11 ubiquitin ligase.	HIVEP2 MAGI3 PDCD4 DENND4C ELMO2	4.09e-05	128	103	5	25332235
Pubmed	Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits.	ABCA1 GCKR PPP4R3B	4.28e-05	23	103	3	22399527
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	SIN3B ABCF3 HK3 KIF27 EP400 FAAP100 FBXO42 CFDP1 FOXO4 DYNC1H1 CUX1	4.85e-05	857	103	11	25609649
Pubmed	ABCA12 regulates ABCA1-dependent cholesterol efflux from macrophages and the development of atherosclerosis.	ABCA1 ABCA12	5.19e-05	4	103	2	23931754
Pubmed	Smek promotes histone deacetylation to suppress transcription of Wnt target gene brachyury in pluripotent embryonic stem cells.	PPP4R3A PPP4R3B	5.19e-05	4	103	2	21423269
Pubmed	The N-terminal coiled coil domain of the cytohesin/ARNO family of guanine nucleotide exchange factors interacts with the scaffolding protein CASP.	CYTIP CUX1	5.19e-05	4	103	2	12052827
Pubmed	CDYL Deficiency Disrupts Neuronal Migration and Increases Susceptibility to Epilepsy.	CDYL CUX1	5.19e-05	4	103	2	28076783
Pubmed	Neutrophil activation by fMLP regulates FOXO (forkhead) transcription factors by multiple pathways, one of which includes the binding of FOXO to the survival factor Mcl-1.	MCL1 FOXO4	5.19e-05	4	103	2	12960271
Pubmed	Suppressor of MEK null (SMEK)/protein phosphatase 4 catalytic subunit (PP4C) is a key regulator of hepatic gluconeogenesis.	PPP4R3A PPP4R3B	5.19e-05	4	103	2	20876121
Pubmed	LINC01554-Mediated Glucose Metabolism Reprogramming Suppresses Tumorigenicity in Hepatocellular Carcinoma via Downregulating PKM2 Expression and Inhibiting Akt/mTOR Signaling Pathway.	HIVEP2 WARS1 POR CCT2 DYNC1H1	6.71e-05	142	103	5	30809309
Pubmed	A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.	HIVEP2 WARS1 PDCD4 DENND4C NAV1 DYNC1H1	6.89e-05	232	103	6	25515538
Pubmed	Histone methylation mediated by NSD1 is required for the establishment and maintenance of neuronal identities.	NRAP MYO18B CUX1	7.01e-05	27	103	3	37995181
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	SIN3B HIRIP3 GPATCH8 PHF8 PWWP2A CHD5 CFDP1 CDYL CUX1	8.39e-05	608	103	9	36089195
Pubmed	Evolutionary analysis of a cluster of ATP-binding cassette (ABC) genes.	ABCA1 ABCA8	8.64e-05	5	103	2	12532264
Pubmed	ABC gene expression profiles have clinical importance and possibly form a new hallmark of cancer.	ABCA12 ABCA8	8.64e-05	5	103	2	28468577
Pubmed	Histone deacetylase associated with mSin3A mediates repression by the acute promyelocytic leukemia-associated PLZF protein.	SIN3B ZBTB16	8.64e-05	5	103	2	9627120
Pubmed	Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.	PPP4R3B NHSL1 CHD5 FBXO42 ARHGAP20	9.55e-05	153	103	5	10718198
Pubmed	A High-Density Map for Navigating the Human Polycomb Complexome.	SIN3B HIVEP2 CCT2 MORC4 TRAK1 PWWP2A YEATS2 FBXO42	1.16e-04	495	103	8	27705803
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	ZBTB16 HIVEP2 ANXA4 MAGI3 VTI1A YEATS2 KIDINS220 TMEM242 SLC41A3 PCNX4 FBXO42 NAV1 CUX1 INVS	1.28e-04	1489	103	14	28611215
Pubmed	Selective Inhibition of FOXO1 Activator/Repressor Balance Modulates Hepatic Glucose Handling.	SIN3B FOXO4	1.29e-04	6	103	2	29056338
Pubmed	Rewiring of RSK-PDZ Interactome by Linear Motif Phosphorylation.	ARHGEF12 MAGI3 GRID2IP	1.41e-04	34	103	3	30726710
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	WARS1 EP400 EIF4A3 ECHDC1 SRPRA CCT2 PDCD4 PPP4R3B YEATS2 SLC25A12 USP42 CDYL DYNC1H1	1.42e-04	1318	103	13	30463901
Pubmed	Fine-scale comparative mapping of the human 7q11.23 region and the orthologous region on mouse chromosome 5G: the low-copy repeats that flank the Williams-Beuren syndrome deletion arose at breakpoint sites of an evolutionary inversion(s).	POR ASL CUX1	1.54e-04	35	103	3	11013070
Pubmed	A genome-wide association study of carotid atherosclerosis in HIV-infected men.	RYR3 MAST4	1.81e-04	7	103	2	20009918
Pubmed	The primary cilium as the cell's antenna: signaling at a sensory organelle.	KIF27 INVS	1.81e-04	7	103	2	16888132
Pubmed	Aberrant regulation of imprinted gene expression in Gtl2lacZ mice.	WARS1 DYNC1H1	1.81e-04	7	103	2	16575184
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	EMC1 EP400 EIF4A3 PPP4R3B MAST4 NRXN2 CHD5 ARHGAP20	1.83e-04	529	103	8	14621295
Pubmed	Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy.	HIRIP3 DAPK1 CCT2 GPATCH8 RPS6KC1 FAT1 SLC25A12	1.97e-04	401	103	7	25852190
Pubmed	Endogenous β-glucocerebrosidase activity in Abca12⁻/⁻epidermis elevates ceramide levels after topical lipid application but does not restore barrier function.	ABCA1 ABCA12	2.40e-04	8	103	2	24293640
Pubmed	A PP4-phosphatase complex dephosphorylates gamma-H2AX generated during DNA replication.	PPP4R3A PPP4R3B	2.40e-04	8	103	2	18614045
Pubmed	microRNA-205-5p is a modulator of insulin sensitivity that inhibits FOXO function.	SIN3B FOXO4	2.40e-04	8	103	2	30174230
Pubmed	Identification of Zika Virus and Dengue Virus Dependency Factors using Functional Genomics.	CYC1 EMC1 EIF4A3 POR KIDINS220 SLC25A12 DYNC1H1	2.69e-04	422	103	7	27342126
Pubmed	A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.	ABCC3 EMC1 NHSL2 MAGI3 DAPK1 DENND4C ALG2 NAV1 NENF	2.93e-04	719	103	9	35337019
Pubmed	Mast4 knockout shows the regulation of spermatogonial stem cell self-renewal via the FGF2/ERM pathway.	ZBTB16 MAST4	3.08e-04	9	103	2	33219327
Pubmed	Purification of ATP-binding cassette transporter A1 and associated binding proteins reveals the importance of beta1-syntrophin in cholesterol efflux.	ABCA1 ARHGEF12	3.08e-04	9	103	2	16192269
Pubmed	Smek promotes corticogenesis through regulating Mbd3's stability and Mbd3/NuRD complex recruitment to genes associated with neurogenesis.	PPP4R3A PPP4R3B	3.08e-04	9	103	2	28467410
Pubmed	Polycystic kidneys caused by sustained expression of Cux1 isoform p75.	CUX1 INVS	3.08e-04	9	103	2	18356167
Pubmed	Human transcription factor protein interaction networks.	SIN3B ATXN7L2 EP400 CCT2 GPATCH8 PHF8 MORC4 YEATS2 FAT1 CHD5 CFDP1 DYNC1H1 CUX1	3.11e-04	1429	103	13	35140242
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	EP400 SRPRA GPATCH8 DENND4C AFAP1L1 JPH1 YEATS2 HAUS8 NAV1	3.37e-04	733	103	9	34672954
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	NHSL2 EIF4A3 MAGI3 CCT2 ALG2 MYLK2 RPS6KC1 SLC25A12 CHD5 DTHD1 PLIN1 CUX1 HCLS1	3.39e-04	1442	103	13	35575683
Pubmed	Common variants near ABCA1, AFAP1 and GMDS confer risk of primary open-angle glaucoma.	ABCA1 ARHGEF12	3.85e-04	10	103	2	25173105
Pubmed	ABCA12 regulates insulin secretion from β-cells.	ABCA1 ABCA12	3.85e-04	10	103	2	32072744
Pubmed	The human ATP-binding cassette (ABC) transporter superfamily.	ABCF3 ABCA12	3.85e-04	10	103	2	11435397
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	CIB1 HIVEP2 WARS1 EIF4A3 MAGI3 CCT2 RYR3 JPH1 PPP4R3B FBXL16 DYNC1H1 CUX1	4.25e-04	1285	103	12	35914814
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	ABCC3 HIVEP2 EP400 FAAP100 TRAK1 NHSL1 FAT1 PCNX4 CHD5 NAV1 DYNC1H1	4.40e-04	1105	103	11	35748872
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	CYC1 SIN3B EMC1 EP400 INTS7 ARHGEF12 SRPRA EXOSC5 GPATCH8 MYLK2 PWWP2A KIDINS220 CDYL	4.83e-04	1497	103	13	31527615
Pubmed	Interrogating the protein interactomes of RAS isoforms identifies PIP5K1A as a KRAS-specific vulnerability.	POR MCL1 SRPRA JPH1 KIDINS220 NF1 CUX1	4.92e-04	467	103	7	30194290
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	CYC1 EMC1 INTS7 POR SRPRA JPH1 KIDINS220 SLC25A12 DYNC1H1 WNK3	4.93e-04	942	103	10	31073040
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	HIRIP3 EP400 GPATCH8 PHF8 PPP4R3A YEATS2 NF1 SLC41A3 USP42	4.99e-04	774	103	9	15302935
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	HIRIP3 EP400 POR SRPRA CCT2 FAT1 KIDINS220 DYNC1H1 CUX1	5.13e-04	777	103	9	35844135
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	SIN3B INTS7 ARHGEF12 MAGI3 PDCD4 RPS6KC1 NF1	5.44e-04	475	103	7	31040226
Pubmed	Liar, a novel Lyn-binding nuclear/cytoplasmic shuttling protein that influences erythropoietin-induced differentiation.	AFAP1L1 HCLS1	5.62e-04	12	103	2	19064729
Pubmed	MRG15 is a novel PALB2-interacting factor involved in homologous recombination.	SIN3B EP400	5.62e-04	12	103	2	19553677
Pubmed	New molecular components supporting ryanodine receptor-mediated Ca(2+) release: roles of junctophilin and TRIC channel in embryonic cardiomyocytes.	RYR3 JPH1	5.62e-04	12	103	2	19095005
Pubmed	Smek1/2 is a nuclear chaperone and cofactor for cleaved Wnt receptor Ryk, regulating cortical neurogenesis.	PPP4R3A PPP4R3B	5.62e-04	12	103	2	29180410
Pubmed	Further mapping and characterization of Naq1, a quantitative trait locus responsible for maternal inferior nurturing ability in RR mice.	POR ASL	5.62e-04	12	103	2	15472464
Pubmed	BioID-based Identification of Skp Cullin F-box (SCF)β-TrCP1/2 E3 Ligase Substrates.	HIVEP2 CCT2 GPATCH8 PDCD4 ELMO2	5.79e-04	226	103	5	25900982
Pubmed	BioID-based proteomic analysis of the Bid interactome identifies novel proteins involved in cell-cycle-dependent apoptotic priming.	ABCF3 CHD5 DYNC1H1	5.92e-04	55	103	3	33067418
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	EP400 MAGI3 NRXN2 NAV1	6.19e-04	130	103	4	12421765
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	HIRIP3 EP400 PDCD4 DENND4C PWWP2A HAUS8 NAV1 CDYL	6.80e-04	645	103	8	25281560
Pubmed	Global phosphoproteome of HT-29 human colon adenocarcinoma cells.	WARS1 HIRIP3 NF1	7.27e-04	59	103	3	16083285
Pubmed	C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.	EMC1 POR SRPRA DENND4C RPS6KC1 JPH1 KIDINS220	7.71e-04	504	103	7	34432599
Pubmed	The histone deacetylase 9 gene encodes multiple protein isoforms.	SIN3B ZBTB16	7.72e-04	14	103	2	12590135
Pubmed	ΔNp63α Suppresses TGFB2 Expression and RHOA Activity to Drive Cell Proliferation in Squamous Cell Carcinomas.	ARHGEF12 YEATS2 TMEM242 HSF4	8.61e-04	142	103	4	30232004
Pubmed	IKAP localizes to membrane ruffles with filamin A and regulates actin cytoskeleton organization and cell migration.	MYLK2 DYNC1H1	8.89e-04	15	103	2	18303054
Pubmed	Investigation of variants identified in caucasian genome-wide association studies for plasma high-density lipoprotein cholesterol and triglycerides levels in Mexican dyslipidemic study samples.	ABCA1 GCKR	8.89e-04	15	103	2	20160193
Pubmed	The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.	SIN3B WARS1 DENND4C KIDINS220 DYNC1H1	1.01e-03	256	103	5	33397691
Pubmed	Joint effects of common genetic variants from multiple genes and pathways on the risk of premature coronary artery disease.	ABCA1 GCKR	1.01e-03	16	103	2	20691829
Pubmed	Neuroblast differentiation during development and in neuroblastoma requires KIF1Bβ-mediated transport of TRKA.	NF1 CHD5	1.01e-03	16	103	2	28637693
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	POR CCT2 AFAP1L1 NHSL1 FAT1 USP42 FRZB USP4	1.04e-03	689	103	8	36543142
Pubmed	Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme.	INTS7 EIF4A3 CCT2 EXOSC5 PHF8 MYLK2	1.10e-03	390	103	6	17643375
Pubmed	The BMP antagonist gremlin 1 contributes to the development of cortical excitatory neurons, motor balance and fear responses.	RYR3 CUX1	1.15e-03	17	103	2	34184027
Pubmed	A Functional Switch of NuRD Chromatin Remodeling Complex Subunits Regulates Mouse Cortical Development.	CHD5 CUX1	1.15e-03	17	103	2	27806305
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	ARHGEF12 MAGI3 SRPRA CCT2 DENND4C JPH1 KIDINS220 DYNC1H1	1.24e-03	708	103	8	39231216
Pubmed	ISG15 Connects Autophagy and IFN-γ-Dependent Control of Toxoplasma gondii Infection in Human Cells.	EMC1 WARS1 POR CCT2 DYNC1H1	1.24e-03	268	103	5	33024031
Interaction	YWHAG interactions	HIVEP2 NHSL2 MAGI3 CCT2 PDCD4 DENND4C MYLK2 TRAK1 AFAP1L1 NHSL1 HAUS8 NF1 GRID2IP MAST4 TINF2 ELMO2 NAV1 FOXO4 DYNC1H1 MAP3K2	3.75e-06	1248	102	20	int:YWHAG
Cytoband	1q32.3	INTS7 NAV1 NENF	3.45e-05	28	103	3	1q32.3
GeneFamily	ATP binding cassette subfamily A	ABCA1 ABCA12 ABCA8	1.88e-05	14	69	3	805
GeneFamily	PDZ domain containing	ARHGEF12 MAGI3 CYTIP GRID2IP MAST4	2.87e-04	152	69	5	1220
Coexpression	GSE1460_INTRATHYMIC_T_PROGENITOR_VS_DP_THYMOCYTE_DN	HIVEP2 POR FAT1 MAST4 ASL FRZB FOXO4	1.23e-05	197	102	7	M3438
Coexpression	GSE5589_UNSTIM_VS_180MIN_LPS_STIM_MACROPHAGE_UP	VTI1A DENND4C FBXL16 NF1 GRID2IP ASL USP4	1.36e-05	200	102	7	M6600
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|RV / Chamber and Cluster_Paper	NRAP ARHGEF12 POR JPH1 FAT1 MAST4 MYO18B	3.02e-07	190	103	7	93c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCell	3'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-LTi-like_NCR+_ILC3\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZBTB16 CYTIP AFAP1L1 MYO18B GIMAP6 HCLS1	4.30e-06	183	103	6	d4a558bc0b8e11be195a7da1468ab38eb477117d
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	NRAP ARHGEF12 POR JPH1 MAST4 MYO18B	5.17e-06	189	103	6	0a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCell	facs-Bladder-nan-3m\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA1 SRPRA PDCD4 TRIM44 NENF DYNC1H1	6.37e-06	196	103	6	44f5b1b474399c9316729155f2ea95a82ca66e30
ToppCell	facs-Bladder-nan-3m-Epithelial\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA1 SRPRA PDCD4 TRIM44 NENF DYNC1H1	6.37e-06	196	103	6	c0e90d964baa2eb4fbd18a52379ccec5d3bf59a8
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ABCC3 ZBTB16 DAPK1 ABCA8 MAST4 ARHGAP20	6.56e-06	197	103	6	0034bae02ee7fcfea520d453ca3c842ab6963b12
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	ZBTB16 MAGI3 VTI1A NHSL1 NF1 CUX1	6.75e-06	198	103	6	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HIRIP3 MAGI3 CYTIP PCNX4 WNK3	2.28e-05	146	103	5	ec1f793409d1a81c0f9323eb3c82ffe01dae0e44
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D122\|Adult / Lineage, Cell type, age group and donor	ZBTB16 ECHDC1 MAGI3 DAPK1 FAT1	3.23e-05	157	103	5	31d1bd9138c60e8485664ec4144f987226e3eef9
ToppCell	Control-MAIT\|World / Disease group and Cell class	ABCC3 ABCA1 ZBTB16 TSGA10 PDCD4	3.86e-05	163	103	5	0ca4b835936b4f82217cbe57210c1dd90986c1d0
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Adult / Lineage, Cell type, age group and donor	ECHDC1 MAGI3 DAPK1 FAT1 MAST4	3.86e-05	163	103	5	e819a1d6d28290854aa0672b3a18fa9e293d8f23
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D231\|Adult / Lineage, Cell type, age group and donor	ARHGEF12 MAGI3 DAPK1 FAT1 MAST4	4.71e-05	170	103	5	269dee5abca9f6aa079f116f0d8f1d198604d9d4
ToppCell	Control-MAIT\|Control / Disease group and Cell class	ABCC3 ABCA1 ZBTB16 WARS1 TSGA10	4.98e-05	172	103	5	552bc62e8e8bb0ac1cd0452f4410a3af087787eb
ToppCell	10x5'-lymph-node_spleen-Myeloid_Mac-Intestinal_macrophages\|lymph-node_spleen / Manually curated celltypes from each tissue	ABCC3 ABCA1 HK3 DAPK1 NHSL1	6.18e-05	180	103	5	7be7d7a6906fff6dbdecd9cb013d855aba4eda2a
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Dendritic-conventional_dendritic_cell-DC_c2-CD1C\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	WARS1 EXOSC5 TRAK1 RPS6KC1 ZNF846	6.34e-05	181	103	5	c8286a7ac8e3cc5aa7e92b043a08435294ea686f
ToppCell	COVID-19-Heart-CM_3\|Heart / Disease (COVID-19 only), tissue and cell type	NPPB NRAP JPH1 MAST4 MYO18B	6.51e-05	182	103	5	287fcc3897ae08841f6f85ae6c9cef16f75b1dd1
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ECHDC1 ARHGEF12 MAGI3 FAT1 MAST4	6.86e-05	184	103	5	102105ae1a5ef6d42a43f6d9b00f12ed0690ddb7
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MAGI3 DAPK1 JPH1 FAT1 MAST4	7.04e-05	185	103	5	98b8ee42b89d97e4c9db01740e0c193503c68f2c
ToppCell	facs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l32-30\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DRP2 HIRIP3 TSGA10 MORC4 CUX1	7.59e-05	188	103	5	c2febf9fd4632af1f922067c3a30e5c50f75f480
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MAGI3 DAPK1 JPH1 NHSL1 MAST4	7.98e-05	190	103	5	8aea807a2bcf0b653b4de6202b6ecb0f0683cc2e
ToppCell	facs-GAT-Fat-3m\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA1 NHSL2 MCL1 KIDINS220 ELMO2	7.98e-05	190	103	5	1d92be1b41cff59e834a9d28868f554bd1f3e471
ToppCell	PCW_13-14\|World / Celltypes from embryonic and fetal-stage human lung	ABCC3 ZBTB16 DAPK1 ABCA8 MAST4	7.98e-05	190	103	5	62a3ec1ae0829602b0569cc051210551644f1d46
ToppCell	ILEUM-non-inflamed\|ILEUM / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	ZBTB16 MCL1 ABCA8 PDCD4 DTHD1	8.18e-05	191	103	5	c4a78ef7b87ffadbb1b9b69cbfa7c164ca456f9a
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MAGI3 DAPK1 JPH1 NHSL1 MAST4	8.18e-05	191	103	5	ca5669bd6f4a17471acae3eb229f845cc2e08efa
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic-Non-classical_Monocyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	WARS1 HK3 NLRC4 CYTIP HCLS1	9.01e-05	195	103	5	10ce1b6961f10372d1f65388cbf3626a5fcd6840
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Club\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MAGI3 DAPK1 FAT1 FBXL16 MAST4	9.23e-05	196	103	5	ed76eeb37400ca154feae9b7ebaddb6c434f8b81
ToppCell	myeloid-CD16+_Monocyte\|World / Lineage and Cell class	ABCC3 WARS1 HK3 FIBCD1 CUX1	9.23e-05	196	103	5	225c102e0a2047425a7125eba1d2359159c50409
ToppCell	remission-Non-classical_Monocyte\|remission / disease stage, cell group and cell class	ABCC3 WARS1 HK3 FIBCD1 CUX1	9.23e-05	196	103	5	049d995986c20ce066bd64fcc2d2f1c2f8899883
ToppCell	control-Non-classical_Monocyte\|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ABCC3 WARS1 HK3 FIBCD1 CUX1	9.23e-05	196	103	5	1d71a5be652dd3281aba4f984f6ef84c993c5f63
ToppCell	COVID-19-Heart-Mito_CM\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CYC1 NPPB NRAP MYLK2 MYO18B	9.46e-05	197	103	5	44e49943d62bfe622b40ad0460093d31540544df
ToppCell	PBMC-Mild-Myeloid-Non-classical_Monocyte\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	ABCC3 WARS1 HK3 DAPK1 FIBCD1	9.46e-05	197	103	5	083fec147040ee0bebac2815fb89355cf3a7ffa5
ToppCell	PBMC-Mild-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ABCC3 WARS1 HK3 DAPK1 FIBCD1	9.46e-05	197	103	5	f0e6745b0fd734ea17e7a2a883e48017e8d3102d
ToppCell	PBMC-Mild-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	ABCC3 WARS1 HK3 DAPK1 FIBCD1	9.46e-05	197	103	5	b82142cf8057a55dfa884248b752173661edffd1
ToppCell	PBMC-Mild-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ABCC3 WARS1 HK3 DAPK1 FIBCD1	9.46e-05	197	103	5	96d56bce69de7192c7a6b43371b56f4acdcc7733
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes-Non-classical_monocytes_L.1.2.2.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	WARS1 HK3 CYTIP CUX1 HCLS1	9.46e-05	197	103	5	b4f6501c266328439cba4f174e594a6a04a252a1
ToppCell	PBMC-Mild-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ABCC3 WARS1 HK3 DAPK1 FIBCD1	9.46e-05	197	103	5	70faaea9c143337a52c8f660ebb063aa92327357
ToppCell	PBMC-Mild-Myeloid-Non-classical_Monocyte\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ABCC3 WARS1 HK3 DAPK1 FIBCD1	9.46e-05	197	103	5	422074930fce25a6ad15ba41e391c65787e7878e
ToppCell	COVID-19_Mild-Myeloid-Non-classical_Monocyte\|COVID-19_Mild / Disease group, lineage and cell class	ABCC3 WARS1 HK3 DAPK1 FIBCD1	9.46e-05	197	103	5	9c943d18f8e6cb0ce9f2158d50796fafae5c81d4
ToppCell	facs-Tongue-nan-3m-Epithelial\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGEF12 MCL1 PDCD4 PPP4R3A PPP4R3B	9.69e-05	198	103	5	2f03f8897dd7cce6d8296638e14e11ec16bcf624
ToppCell	remission-Non-classical_Monocyte\|World / disease stage, cell group and cell class	ABCC3 WARS1 HK3 FIBCD1 CUX1	9.69e-05	198	103	5	1c170655070acca00520b7cf9c510a04c0a90a8f
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Club\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MAGI3 DAPK1 PDCD4 FAT1 MAST4	9.69e-05	198	103	5	1408e02e053ad3406229bfe8189da03be6366e81
ToppCell	facs-Tongue-nan-3m\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGEF12 MCL1 PDCD4 PPP4R3A PPP4R3B	9.69e-05	198	103	5	f2a4057f038ef7225a5b98a7ab068c30dff4eadd
ToppCell	PBMC-Convalescent-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte-\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ABCC3 WARS1 HK3 FIBCD1 CUX1	9.92e-05	199	103	5	99eec995aa20ac22a8dd045382bd15a15db0b87a
ToppCell	PBMC-Convalescent-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte\|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)	ABCC3 WARS1 HK3 FIBCD1 CUX1	9.92e-05	199	103	5	aca9f75c690c6ed952bcbdc7e1e7eef7719f54ca
ToppCell	PBMC-Convalescent-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ABCC3 WARS1 HK3 FIBCD1 CUX1	9.92e-05	199	103	5	3e09b3c2e2c57e5248981293020d2434e898e3e1
ToppCell	PBMC-Convalescent-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte-\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ABCC3 WARS1 HK3 FIBCD1 CUX1	9.92e-05	199	103	5	ae6b4b4557c6a9223acdee2a79bc780c5916d38a
ToppCell	PBMC-Convalescent-Myeloid-Non-classical_Monocyte\|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)	ABCC3 WARS1 HK3 FIBCD1 CUX1	9.92e-05	199	103	5	4eed28ef8c74d7131eeeabdd732a682d91e034dd
ToppCell	PBMC-Convalescent-Myeloid-Non-classical_Monocyte\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ABCC3 WARS1 HK3 FIBCD1 CUX1	9.92e-05	199	103	5	f234533254fd82b1ef2041e8405fe201d874018b
ToppCell	COVID-19_Convalescent-Myeloid-Non-classical_Monocyte\|COVID-19_Convalescent / Disease group, lineage and cell class	ABCC3 WARS1 HK3 FIBCD1 CUX1	9.92e-05	199	103	5	5253948a1d7fc3da571860e14cdde4e18222e13b
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW26\|fetalBrain_Zhong_nature / Sample Type, Dataset, Time_group, and Cell type.	MAST4 NRXN2 CHD5 FRZB ARHGAP20	1.02e-04	200	103	5	61d7dd0a78942b069c3f5e75044368dc00e6e8e6
ToppCell	COVID-19-COVID-19_Mild-Myeloid-CD16+_Monocyte\|COVID-19_Mild / Disease, condition lineage and cell class	ABCC3 WARS1 HK3 DAPK1 FIBCD1	1.02e-04	200	103	5	5c0eb14bdf1bfeaf93f6c3d521529bd5a4de50ce
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Activated_Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	HIVEP2 ARHGEF12 NF1 MAST4 GIMAP6	1.02e-04	200	103	5	2d07237022b409c4fac6fcf99b68c8affb3007cd
ToppCell	mild-Non-classical_Monocyte\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ABCC3 WARS1 HK3 FIBCD1 CUX1	1.02e-04	200	103	5	692b48da9fd56bafcb3c8b33b0fe369160881c45
ToppCell	mild-Non-classical_Monocyte\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ABCC3 WARS1 HK3 DAPK1 CUX1	1.02e-04	200	103	5	334bab6bf93d455f3526e817ea5785d8b6ee531c
ToppCell	COVID-19-COVID-19_Convalescent-Myeloid-CD16+_Monocyte\|COVID-19_Convalescent / Disease, condition lineage and cell class	ABCC3 WARS1 HK3 FIBCD1 CUX1	1.02e-04	200	103	5	f24abb2d54d6423ee886285e3c66a874ec59e1a3
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW26\|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.	MAST4 NRXN2 CHD5 FRZB ARHGAP20	1.02e-04	200	103	5	5c7263c862093ad9dbc81d06b16b6f74e8a6b634
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Monocytic-Monocyte_CD16\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ABCC3 WARS1 HK3 NLRC4 HCLS1	1.02e-04	200	103	5	fc061de0db2e8b5ca47f5e2a1e861018e7f1b582
Drug	Protoveratrine A [143-57-7]; Down 200; 5uM; MCF7; HT_HG-U133A	EMC1 SRPRA KIDINS220 NF1 MAST4 ELMO2 FBXO42 TRIM44 MAP3K2	2.59e-07	197	102	9	4963_DN
Drug	docetaxel	ABCC3 NPPB ABCA1 ABCA12 POR MCL1 ABCA8	2.31e-06	133	102	7	ctd:C067311
Drug	Albendazole [54965-21-8]; Up 200; 15uM; MCF7; HT_HG-U133A	EMC1 INTS7 ABCA12 TRAK1 MAST4 FBXO42 FRZB HCLS1	2.66e-06	194	102	8	7164_UP
Disease	Charcot-Marie-Tooth disease	WARS1 DRP2 JPH1 DYNC1H1	1.26e-05	42	100	4	cv:C0007959
Disease	Colorectal Neoplasms	ABCC3 ABCA1 ABCA12 VTI1A ABCA8 FAT1 CHD5	4.53e-05	277	100	7	C0009404
Disease	trans fatty acid measurement, trans/trans-18:2 fatty acid measurement	RYR3 CYTIP MYO18B	7.26e-05	24	100	3	EFO_0006821, EFO_0006826
Disease	platelet crit	ZBTB16 NHSL2 EIF4A3 ARHGEF12 GCKR GPATCH8 MYLK2 PWWP2A FBXL16 NF1 MAST4 CUX1	9.21e-05	952	100	12	EFO_0007985
Disease	Colorectal Carcinoma	ABCC3 ABCA1 HK3 ABCA12 VTI1A ABCA8 FAT1 NF1 CHD5 CUX1	1.38e-04	702	100	10	C0009402
Disease	Large cell carcinoma of lung	MYO18B WNK3 MAP3K2	1.74e-04	32	100	3	C0345958
Disease	Squamous cell carcinoma of lung	MAST4 MYO18B WNK3	1.74e-04	32	100	3	C0149782
Disease	urinary albumin to creatinine ratio	ZBTB16 POR CCT2 GCKR FAT1	3.67e-04	179	100	5	EFO_0007778
Disease	sleep disorder (implicated_via_orthology)	TFAP2E NF1	6.13e-04	11	100	2	DOID:535 (implicated_via_orthology)
Disease	outer ear morphology trait	HIVEP2 CUX1	7.34e-04	12	100	2	EFO_0007664
Disease	ADHD symptom measurement	ARHGEF12 CUX1	7.34e-04	12	100	2	EFO_0007860
Disease	Sarcoma, Spindle Cell	MCL1 NF1	1.01e-03	14	100	2	C0205945
Disease	Sarcoma, Epithelioid	MCL1 NF1	1.01e-03	14	100	2	C0205944
Disease	free cholesterol in medium HDL measurement	ABCA1 GCKR ABCA8	1.02e-03	58	100	3	EFO_0022267
Disease	cholesterol in medium HDL measurement	ABCA1 GCKR ABCA8	1.07e-03	59	100	3	EFO_0021903
Disease	total lipids in HDL measurement	ABCA1 GCKR ABCA8	1.29e-03	63	100	3	EFO_0022307
Disease	coffee consumption, cups of coffee per day measurement	POR GCKR	1.32e-03	16	100	2	EFO_0004330, EFO_0006782
Disease	protein C measurement	GCKR MAP3K2	1.50e-03	17	100	2	EFO_0004633
Disease	Charcot-Marie-Tooth disease type 2	JPH1 DYNC1H1	1.50e-03	17	100	2	cv:C0270914
Disease	Sarcoma	MCL1 NF1	2.29e-03	21	100	2	C1261473
Disease	Leukemia, Myelocytic, Acute	ANXA4 DAPK1 NF1 CUX1	2.89e-03	173	100	4	C0023467
Disease	neuroimaging measurement, brain volume measurement	MYLK2 PPP4R3A JPH1 NF1 MAST4	2.94e-03	286	100	5	EFO_0004346, EFO_0006930

Protein segments in the cluster

Peptide	Gene	Start	Entry
SGMSGRKRKASISLT	EP400	931	Q96L91
LDAGASGSKDMKVLR	DAPK1	931	P53355
GSSLVKSSGKLMLLQ	CHD5	1016	Q8TDI0
VGTLSGGMKRKLSIS	ABCA12	1476	Q86UK0
SGGNKRKLSTAMALI	ABCA1	2046	O95477
RNGLGKTTLLKMLAT	ABCF3	211	Q9NUQ8
ALSSKSGLSRGRKVM	CYC1	46	P08574
KSMKGLGTDDNTLIR	ANXA4	256	P09525
MKASESSRLKLEGSL	CCDC154	261	A6NI56
LSAKTKTALSMGLNG	ATXN7L2	601	Q5T6C5
KRSMGLTLAESELTK	ARHGEF12	486	Q9NZN5
ESLKGLDKMFLSSVG	TFAP2E	411	Q6VUC0
SLKLGMLSVLSTLSG	INTS7	306	Q9NVH2
KGMSLLVRAESDGSL	PPP4R3A	36	Q6IN85
GKSSLVSALLGEMEK	ABCC3	666	O15438
SGVLSLKRSLMDGLG	FAT1	621	Q14517
LKRSLMDGLGAKVSF	FAT1	626	Q14517
LRRSLEAIKAMSSKG	FBXO42	556	Q6P3S6
LGEMTKLGSKTALNR	KIDINS220	886	Q9ULH0
AKGSRKMARLGSTSG	HIRIP3	346	Q9BW71
GVLVRASLKKSTMGF	MAGI3	406	Q5TCQ9
LLRKMASSSGEGKEL	POR	401	P16435
SGKGKSTLLQRIAML	NLRC4	171	Q9NPP4
SKSGNMASLTISGLK	IGLV2-33	86	A0A075B6J2
KGKAMGTADSRLLHS	NRAP	591	Q86VF7
RLTSLGEDVSKGMAK	GPR179	1851	Q6PRD1
SDGGSMLKALPLKSS	RPS6KC1	461	Q96S38
EMAKSLLKTASLSGR	ECHDC1	6	Q9NTX5
SRGLEKAGLLTKAEM	ASL	46	P04424
TMATSGSARKRLLKE	EIF4A3	6	P38919
SLLGSMKLRKSESKS	JPH1	216	Q9HDC5
DKATLSMGRLVLSNK	CUX1	601	Q13948
LLLKKGSRSDTSARM	NHSL1	1426	Q5SYE7
DGGSLASTLSKLKRM	GPATCH8	366	Q9UKJ3
LLKDSLGGSAKTVMI	KIF27	301	Q86VH2
SLNLSDMGHKIGTKS	PCNX4	326	Q63HM2
DKATVLLSMSKGGKR	PDCD4	296	Q53EL6
ASMDSSSKLLRGRSK	FOXO4	196	P98177
RFKKISSSGALMALG	MYLK2	581	Q9H1R3
KRLQTICLSGTGMKS	MAP3K2	506	Q9Y2U5
LLDMGSGGIKLRASS	NRXN2	566	Q9P2S2
LTGKDSTRGVAKMSL	NENF	91	Q9UMX5
SGGSLLGDKTRMTEL	MMAA	186	Q8IVH4
KMDRISSSSGLGCKV	NPPB	116	P16860
DSVERKLLMSSTKGL	EXOSC5	186	Q9NQT4
KGMSLLVRAESDGSL	PPP4R3B	36	Q5MIZ7
GGTKLLALSAKGRLM	FAAP100	416	Q0VG06
KAMAKGLRGEASSLR	HK3	506	P52790
KMSEGGRKSSLLQKS	HAUS8	61	Q9BT25
LKLACGSKTSSVIMG	OR10H3	186	O60404
TKGRAMSLSDALKGV	PLIN1	376	O60240
GSSRMKGGSATKILL	GCKR	256	Q14397
SGLKRSSGMSSLLGK	CFDP1	216	Q9UEE9
SRLNSSFKGKMGTVS	GRID2IP	561	A4D2P6
GASANEMLLSGRKLT	CDYL	496	Q9Y232
GLSALLGKDMSSELT	ELMO2	661	Q96JJ3
SFSSESRAGMLLKKS	DENND4C	1046	Q5VZ89
SRAGMLLKKSSLDSN	DENND4C	1051	Q5VZ89
KGLALKSSMDSRISL	DTHD1	311	Q6ZMT9
LSSMFGTLPRKSRKG	CYTIP	321	O60759
SNAGGKRKLSLMLDE	HSF4	201	Q9ULV5
GKVTKSLSASALSLM	MAST4	1081	O15021
GDSLLKHSGMRFTTK	FIBCD1	376	Q8N539
SLSGDSRLKMRAELG	DYNC1H1	2501	Q14204
KADGLLGMFLKRLSS	EMC1	476	Q8N766
GRSGKMRALSFKTGI	DRP2	486	Q13474
TKPMGRSGATSRKAL	MCL1	196	Q07820
GKGSDDVLRTMLSLK	INVS	331	Q9Y283
GSKGREAPLMSKTLS	NAV1	126	Q8NEY1
KAMSLKRSTITDAGL	FBXL16	196	Q8N461
SDLVKKLGQGSRSMD	ARHGAP20	601	Q9P2F6
TSGAMLTGELKKALI	WARS1	421	P23381
NDSSLKTGLEKMRSG	PWWP2A	486	Q96N64
ELRSKDSGGLKAAMI	TRIM44	221	Q96DX7
LRLILMGKTGSGKSA	GIMAP6	41	Q6P9H5
ASSGTRGLKAKFESM	HCLS1	231	P14317
LDLSGMSISIRSKTK	NHSL2	781	Q5HYW2
KSGSMRLGKDALVFT	MORC4	126	Q8TE76
MKLRGTKDLSIAAVG	SIN3B	286	O75182
KGMDKILLSSGRDAS	CCT2	46	P78371
GLKGNLEMTLASRLS	SLC41A3	111	Q96GZ6
SSLNKMRKTIGGVAL	ABCA8	826	O94911
KSSLAELKGSMSRAA	AFAP1L1	376	Q8TED9
ELKGSMSRAAGRKIT	AFAP1L1	381	Q8TED9
SLKATMGLAGRARVK	ALG2	381	Q9H553
MGGSGSRLSKELLAE	CIB1	1	Q99828
KSKSGMISGLDFSDI	SLC25A12	171	O75746
LTSGILMGAKLSKQT	TRAK1	936	Q9UPV9
RLSNKLKGSTDEMSA	USP42	721	Q9H9J4
DGKLLKLNSRSTLAM	USP4	726	Q13107
ILAGSELFKRSLMSG	ZNF846	46	Q147U1
SKLGELAVGMKSESR	ZBTB16	386	Q05516
KKRLALSTAIARSGM	SLC16A4	141	O15374
MKLRHLGLSKSDSSN	FRZB	291	Q92765
VMKSGSELVKAGLRA	RYR3	2941	Q15413
LAMGTRAASTGKSKS	TINF2	316	Q9BSI4
DANLGKSSRILTGML	VTI1A	171	Q96AJ9
ASLRKGKGNSSMDSA	NF1	656	P21359
FGMLKGLVGSKSLSR	SRPRA	321	P08240
LLLGTMEDGKTSVSK	MYO18B	1816	Q8IUG5
SLGESLAMKEKTISG	TSGA10	286	Q9BZW7
ALLMSNGSTKRVKSL	PHF8	606	Q9UPP1
HGRMLKGISSSSLKE	HIVEP2	611	P31629
GMLAGFITTLSLAKK	TMEM242	41	Q9NWH2
GGQASLMKISDSTLK	YEATS2	916	Q9ULM3
KIGDLGLATLMRTSF	WNK3	291	Q9BYP7
GSSMQSGSELLLKER	WNK3	1446	Q9BYP7