Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	modification-dependent protein binding	PRPF8 BPTF	1.55e-03	206	6	2	GO:0140030
GeneOntologyBiologicalProcess	endoderm development	LEO1 BPTF	2.67e-04	88	6	2	GO:0007492
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	LEO1 PRPF8 MADD KCNQ2	2.62e-05	1285	6	4	35914814
Pubmed	Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.	LEO1 PRPF8 MADD	7.11e-05	538	6	3	28524877
Pubmed	A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse.	MADD KCNQ2	8.80e-05	85	6	2	23055939
Interaction	SLC7A6OS interactions	LEO1 PRPF8	2.78e-05	28	6	2	int:SLC7A6OS
Coexpression	ULE_SPLICING_VIA_NOVA2	KCNQ2 BPTF	3.93e-05	43	6	2	M1551
Coexpression	ULE_SPLICING_VIA_NOVA2	KCNQ2 BPTF	3.93e-05	43	6	2	MM666
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MADD KCNQ2	2.52e-04	186	6	2	7278a1a1bf9bb27aeb03852134defb31b62f30d6
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MADD KCNQ2	2.72e-04	193	6	2	0c652ebe22ce5d2927599dd97ef1920547858395
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MADD KCNQ2	2.72e-04	193	6	2	8689a70a33a7c3823dc647d41ac0160e7c3ae396
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MADD KCNQ2	2.72e-04	193	6	2	be28070c049e7cb68bcd54f582226eb2f5e4bc1c
Drug	2,3-dihydroxybenzoic acid	MADD KCNQ2	1.88e-05	26	6	2	CID000000019
Drug	pyrazinamide	LEO1 MADD	1.31e-04	68	6	2	CID000001046
Drug	etomidate	LEO1 KCNQ2	1.43e-04	71	6	2	CID000036339
Disease	phospholipids:total lipids ratio	MADD BPTF	8.66e-04	227	6	2	EFO_0020946
Disease	cholesteryl esters:total lipids ratio, high density lipoprotein cholesterol measurement	MADD BPTF	9.91e-04	243	6	2	EFO_0004612, EFO_0020944
Disease	cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement	MADD BPTF	1.28e-03	276	6	2	EFO_0004612, EFO_0020943
Disease	sexual dimorphism measurement	MADD BPTF	1.90e-02	1106	6	2	EFO_0021796

Protein segments in the cluster

Peptide	Gene	Start	Entry
PFLEPVDPNDAPDYY	BPTF	2951	Q12830
PRPFDPQYYEDEFED	LEO1	386	Q8WVC0
PYFEPQYGFPPEEDE	MADD	771	Q8WXG6
EAYFGAKEPEPAPPY	KCNQ2	656	O43526
EPFTEEPNEVFPYPD	FAM217A	236	Q8IXS0
FPPFDDEEPPLDYAD	PRPF8	166	Q6P2Q9