Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionhistone binding

SFMBT1 VRK1 ATRX KDM5A NOC2L CHD1 MORC4 MSH6 UHRF1 CTSV

1.15e-0526513310GO:0042393
GeneOntologyMolecularFunctionmethylated histone binding

ATRX KDM5A CHD1 MORC4 MSH6 UHRF1

2.37e-05861336GO:0035064
GeneOntologyMolecularFunctionmethylation-dependent protein binding

ATRX KDM5A CHD1 MORC4 MSH6 UHRF1

2.70e-05881336GO:0140034
GeneOntologyMolecularFunctionpyrophosphatase activity

ABCA1 RNGTT ATRX ABCA13 CHD1 OLA1 RFC1 ARL15 MORC4 RGS12 NLRP3 DHX30 SEPTIN2 ARL4A ABCG1 MTIF2 GNL2

4.30e-0583913317GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

ABCA1 RNGTT ATRX ABCA13 CHD1 OLA1 RFC1 ARL15 MORC4 RGS12 NLRP3 DHX30 SEPTIN2 ARL4A ABCG1 MTIF2 GNL2

4.36e-0584013317GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

ABCA1 RNGTT ATRX ABCA13 CHD1 OLA1 RFC1 ARL15 MORC4 RGS12 NLRP3 DHX30 SEPTIN2 ARL4A ABCG1 MTIF2 GNL2

4.36e-0584013317GO:0016818
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

ABCA1 ATRX ABCA13 CHD1 OLA1 RFC1 ARL15 MORC4 RGS12 NLRP3 DHX30 SEPTIN2 ARL4A ABCG1 MTIF2 GNL2

5.89e-0577513316GO:0017111
GeneOntologyMolecularFunctionDNA ligase (ATP) activity

LIG1 LIG4

1.32e-0431332GO:0003910
GeneOntologyMolecularFunctionDNA ligase activity

LIG1 LIG4

1.32e-0431332GO:0003909
GeneOntologyMolecularFunctionactin filament binding

ESPN MYO5A NEB LCP1 EGFR SIPA1L1 TLN1 ANTXR1

1.43e-042271338GO:0051015
GeneOntologyMolecularFunctionATP-dependent activity

ABCA1 ATRX MYO5A ABCA13 ACSM1 CHD1 OLA1 RFC1 MORC4 NLRP3 DHX30 MSH6 ABCG1

2.36e-0461413313GO:0140657
GeneOntologyMolecularFunctionGTP binding

NPR1 RNGTT SCG5 ACSM1 OLA1 ARL15 SEPTIN2 ARL4A MTIF2 GNL2

3.32e-0439713310GO:0005525
GeneOntologyMolecularFunctionhistone H2AX kinase activity

VRK1 PRKDC

4.35e-0451332GO:0141003
GeneOntologyMolecularFunctionguanyl ribonucleotide binding

NPR1 RNGTT SCG5 ACSM1 OLA1 ARL15 SEPTIN2 ARL4A MTIF2 GNL2

7.26e-0443913310GO:0032561
GeneOntologyMolecularFunctionguanyl nucleotide binding

NPR1 RNGTT SCG5 ACSM1 OLA1 ARL15 SEPTIN2 ARL4A MTIF2 GNL2

7.26e-0443913310GO:0019001
GeneOntologyMolecularFunctionATP hydrolysis activity

ABCA1 ATRX ABCA13 CHD1 OLA1 RFC1 MORC4 NLRP3 DHX30 ABCG1

7.51e-0444113310GO:0016887
GeneOntologyMolecularFunctionligase activity, forming phosphoric ester bonds

LIG1 LIG4

9.05e-0471332GO:0016886
GeneOntologyMolecularFunctionphosphatidylcholine floppase activity

ABCA1 ABCG1

1.20e-0381332GO:0090554
GeneOntologyMolecularFunctionATP-dependent activity, acting on DNA

ATRX CHD1 RFC1 DHX30 MSH6

1.62e-031271335GO:0008094
GeneOntologyMolecularFunctioncatalytic activity, acting on DNA

ATRX CHD1 RFC1 DHX30 LIG1 MSH6 LIG4

1.89e-032621337GO:0140097
DomainDNA_ligase_ATP-dep_C

LIG1 LIG4

1.46e-0431312IPR012309
DomainDNA_ligase_ATP-dep_N

LIG1 LIG4

1.46e-0431312IPR012308
DomainDNA_ligase_ATP-dep_cent

LIG1 LIG4

1.46e-0431312IPR012310
DomainDNA_LIGASE_A2

LIG1 LIG4

1.46e-0431312PS00333
DomainDNA_LIGASE_A3

LIG1 LIG4

1.46e-0431312PS50160
DomainDNA_ligase_ATP-dep

LIG1 LIG4

1.46e-0431312IPR000977
DomainDNA_ligase_ATP-dep_CS

LIG1 LIG4

1.46e-0431312IPR016059
DomainDNA_ligase_A_M

LIG1 LIG4

1.46e-0431312PF01068
Domain-

LIG1 LIG4

1.46e-04313121.10.3260.10
DomainDNA_LIGASE_A1

LIG1 LIG4

1.46e-0431312PS00697
DomainDNA_ligase_A_C

LIG1 LIG4

1.46e-0431312PF04679
DomainDNA_ligase_A_N

LIG1 LIG4

1.46e-0431312PF04675
DomainPP2A_PR55_CS

PPP2R2B PPP2R2C

2.90e-0441312IPR018067
DomainPP2A_PR55

PPP2R2B PPP2R2C

2.90e-0441312IPR000009
DomainPR55_2

PPP2R2B PPP2R2C

2.90e-0441312PS01025
DomainPR55_1

PPP2R2B PPP2R2C

2.90e-0441312PS01024
DomainP-loop_NTPase

ABCA1 ATRX MYO5A ABCA13 CHD1 OLA1 RFC1 ARL15 NLRP3 DHX30 SEPTIN2 MSH6 ARL4A ABCG1 MTIF2 GNL2

2.96e-0484813116IPR027417
DomainZF_PHD_2

ATRX KDM5A DIDO1 TAF3 UHRF1

5.50e-04951315PS50016
DomainZF_PHD_1

ATRX KDM5A DIDO1 TAF3 UHRF1

5.77e-04961315PS01359
DomainGF_recep_IV

EGFR PCSK6

7.19e-0461312PF14843
DomainGF_recep_IV

EGFR PCSK6

7.19e-0461312IPR032778
Domain-

PDSS1 FDFT1

7.19e-04613121.10.600.10
Domain-

ABCA1 ATRX ABCA13 CHD1 OLA1 RFC1 ARL15 DHX30 SEPTIN2 MSH6 ARL4A ABCG1 MTIF2 GNL2

7.58e-04746131143.40.50.300
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

VRK1 KDM5A NOC2L AHCTF1 DIDO1 NCBP1 CHD1 RO60 RFC1 LCP1 DHX30 LIG1 MSH6 TAF3 FDFT1 POP1 GNL2 FADS2 CRYBG1 STIP1 PRKDC PTCD3

1.23e-0813181382230463901
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

EML4 GRB2 DIDO1 NCBP1 CHD1 SEC31A OLA1 RFC1 CPT1A DHX30 MSH6 TXNDC5 UBE2H EGFR TLN1 POP1 GNL2 STIP1 PRKDC CTNND1 CTSV PTCD3

4.32e-0814151382228515276
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

MYO5A NOC2L AHCTF1 DIDO1 NCBP1 CHD1 RFC1 LCP1 DHX30 MSH6 TLN1 POP1 GNL2 PRKDC PTCD3

5.62e-086531381522586326
Pubmed

K25 (K25irs1), K26 (K25irs2), K27 (K25irs3), and K28 (K25irs4) represent the type I inner root sheath keratins of the human hair follicle.

KRT26 KRT27 KRT25

6.11e-083138316874310
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

ATRX MYO5A NOC2L AHCTF1 GPAT3 PSD3 GRB2 CHD1 TNFRSF10B DHX30 TXNDC5 EGFR FDFT1 MTIF2 TLN1 POP1 GNL2 FADS2 MAP7D2 STIP1 CTNND1 PTCD3

1.02e-0714871382233957083
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

VRK1 ATRX KDM5A AHCTF1 DIDO1 NCBP1 CHD1 RFC1 MSH6 TAF3 GNL2 UHRF1 ZFP82 FOXC1

1.55e-076081381436089195
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

ATRX NOC2L AHCTF1 CHD1 BRMS1L RFC1 MORC4 LIG1 TAF3 UHRF1 CRYBG1 PTCD3

4.13e-074691381227634302
Pubmed

Dysfunction of GRAP, encoding the GRB2-related adaptor protein, is linked to sensorineural hearing loss.

GRB2 GRAPL GRAP

6.08e-075138330610177
Pubmed

The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.

KRT26 CLTCL1 PDSS1 KDM5A KRT27 NCBP1 CHD1 RO60 LCP1 DHX30 TXNDC5 FDFT1 POP1 OSBPL1A PRKDC KRT25 CDK3 PTCD3

7.78e-0711531381829845934
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

VRK1 ATRX NOC2L NCBP1 CHD1 RO60 SEC31A OLA1 RFC1 DHX30 SEPTIN2 MSH6 TXNDC5 TLN1 GNL2 UHRF1 STIP1 PRKDC CTNND1 PTCD3

9.44e-0714251382030948266
Pubmed

Defective cholesterol clearance limits remyelination in the aged central nervous system.

ABCA1 NLRP3 ABCG1

1.21e-066138329301957
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

MYO5A DHX30 MSH6 ARAP3 EGFR CRYBG1 EIF2AK4 PRKDC

1.57e-06202138833005030
Pubmed

Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions.

NPR1 MAN1A1 ITGA6 CHD1 SEC31A LIG1 EGFR PRKDC NOS2

1.72e-06276138928319085
Pubmed

Two distinct tyrosine-based motifs enable the inhibitory receptor FcgammaRIIB to cooperatively recruit the inositol phosphatases SHIP1/2 and the adapters Grb2/Grap.

GRB2 GRAPL GRAP

2.11e-067138315456754
Pubmed

Cholesterol Accumulation in Dendritic Cells Links the Inflammasome to Acquired Immunity.

ABCA1 NLRP3 ABCG1

2.11e-067138328479366
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

MYO5A NOC2L AHCTF1 ITGA6 DIDO1 NCBP1 RFC1 DHX30 SEPTIN2 MSH6 EGFR SIPA1L1 POP1 GNL2 CRYBG1 PRKDC CTNND1 PTCD3

2.63e-0612571381836526897
Pubmed

Glyburide inhibits the Cryopyrin/Nalp3 inflammasome.

ABCA1 NLRP3 ABCG1

3.37e-068138319805629
Pubmed

Cholesterol Efflux Pathways Suppress Inflammasome Activation, NETosis, and Atherogenesis.

ABCA1 NLRP3 ABCG1

3.37e-068138329588315
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

RNGTT MYO5A PSD3 GRB2 ITGA6 NCBP1 MSH6 C2CD3 TXNDC5 EGFR FDFT1 GNL2 STIP1 EIF2AK4 CTNND1 FOXC1

4.49e-0610491381627880917
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

ESPN CLTCL1 ATRX MYO5A KDM5A NHSL2 NOC2L FAM47B NCBP1 NEB LCP1 LIG4 C2CD3 ANTXR1 MAP7D2 EIF2AK4 PRKDC NGLY1 FBXO15

4.52e-0614421381935575683
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

VRK1 ATRX KDM5A ACSM1 GRB2 CHD1 SEC31A OLA1 MED13L SENP8 DHX30 MSH6 TAF3 UBE2H FDFT1 UQCC1 STIP1 EIF2AK4

5.56e-0613271381832694731
Pubmed

A proteomics approach to identify proliferating cell nuclear antigen (PCNA)-binding proteins in human cell lysates. Identification of the human CHL12/RFCs2-5 complex as a novel PCNA-binding protein.

RFC1 LIG1 MSH6 PRKDC

6.87e-0631138412171929
Pubmed

MUC20 suppresses the hepatocyte growth factor-induced Grb2-Ras pathway by binding to a multifunctional docking site of met.

GRB2 EGFR GAB4

7.19e-0610138315314156
Pubmed

Genetic variants in apoptosis and immunoregulation-related genes are associated with risk of chronic lymphocytic leukemia.

TNFRSF10B ESCO1 LIG4 EGFR IL1RL1 PRKDC NOS2

7.82e-06179138719074885
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

KDM5A EML4 AHCTF1 DIDO1 NCBP1 OLA1 RFC1 TAF3 TXNDC5 PCSK6 TLN1 POP1 GNL2 FADS2 UHRF1 EIF2AK4 CTNND1 PTCD3

8.67e-0613711381836244648
Pubmed

A protein interaction landscape of breast cancer.

MYO5A GPAT3 RO60 SEC31A OLA1 DHX30 MSH6 EGFR FDFT1 TLN1 CTNND1 PTCD3

9.18e-066341381234591612
Pubmed

MYC multimers shield stalled replication forks from RNA polymerase.

NOC2L DIDO1 CHD1 RFC1 DHX30 LIG1 MSH6 TXNDC5 POP1 GNL2 FADS2 UHRF1 PRKDC CTNND1 PTCD3

9.74e-069891381536424410
Pubmed

UV-radiation induces dose-dependent regulation of p53 response and modulates p53-HDM2 interaction in human fibroblasts.

VRK1 ANTXR1 PRKDC

9.85e-0611138311709713
Pubmed

A Large-scale genetic association study of esophageal adenocarcinoma risk.

DIDO1 TLR10 LIG1 MSH6 LIG4 EGFR POP1 NOS2 FOXC1

1.20e-05351138920453000
Pubmed

The human type I keratin gene family: characterization of new hair follicle specific members and evaluation of the chromosome 17q21.2 gene domain.

KRT26 KRT27 KRT25

1.31e-0512138315617563
Pubmed

Quantitative mass spectrometry of diabetic kidney tubules identifies GRAP as a novel regulator of TGF-beta signaling.

GRAPL GRAP

1.56e-052138219836472
Pubmed

Loss of both ABCA1 and ABCG1 results in increased disturbances in islet sterol homeostasis, inflammation, and impaired β-cell function.

ABCA1 ABCG1

1.56e-052138222315310
Pubmed

Grap negatively regulates T-cell receptor-elicited lymphocyte proliferation and interleukin-2 induction.

GRAPL GRAP

1.56e-052138211971956
Pubmed

ABCA1 and ABCG1 DNA methylation in epicardial adipose tissue of patients with coronary artery disease.

ABCA1 ABCG1

1.56e-052138234837967
Pubmed

Genetic variations in ABCA1/G1 associated with plasma lipid levels and risk of ischemic stroke.

ABCA1 ABCG1

1.56e-052138235219812
Pubmed

Protein photo-cross-linking in mammalian cells by site-specific incorporation of a photoreactive amino acid.

GRB2 EGFR

1.56e-052138215782189
Pubmed

Regulation of the cholesterol efflux transporters ABCA1 and ABCG1 in retina in hemochromatosis and by the endogenous siderophore 2,5-dihydroxybenzoic acid.

ABCA1 ABCG1

1.56e-052138224462739
Pubmed

Impact of Perturbed Pancreatic β-Cell Cholesterol Homeostasis on Adipose Tissue and Skeletal Muscle Metabolism.

ABCA1 ABCG1

1.56e-052138227702832
Pubmed

Uraemic plasma decreases the expression of ABCA1, ABCG1 and cell-cycle genes in human coronary arterial endothelial cells.

ABCA1 ABCG1

1.56e-052138217082211
Pubmed

EGFR-GRB2 Protein Colocalization Is a Prognostic Factor Unrelated to Overall EGFR Expression or EGFR Mutation in Lung Adenocarcinoma.

GRB2 EGFR

1.56e-052138227449805
Pubmed

p62/mTOR/LXRα pathway inhibits cholesterol efflux mediated by ABCA1 and ABCG1 during autophagy blockage.

ABCA1 ABCG1

1.56e-052138231101336
Pubmed

Impaired ABCA1/ABCG1-mediated lipid efflux in the mouse retinal pigment epithelium (RPE) leads to retinal degeneration.

ABCA1 ABCG1

1.56e-052138230864945
Pubmed

HUNK phosphorylates EGFR to regulate breast cancer metastasis.

HUNK EGFR

1.56e-052138231597954
Pubmed

Detection of EGFR mutations and EML4-ALK rearrangements in lung adenocarcinomas using archived cytological slides.

EML4 EGFR

1.56e-052138223408463
Pubmed

FOXC1 is a critical mediator of EGFR function in human basal-like breast cancer.

EGFR FOXC1

1.56e-052138225124473
Pubmed

Human EMR2, a novel EGF-TM7 molecule on chromosome 19p13.1, is closely related to CD97.

ADGRE2 ADGRE1

1.56e-052138210903844
Pubmed

Associations of ATP-binding cassette transporter A1 and G1 with insulin secretion in human insulinomas.

ABCA1 ABCG1

1.56e-052138222466164
Pubmed

Protective role of p120-catenin on mitochondria by inhibiting NLRP3 in ventilator-induced lung injury.

NLRP3 CTNND1

1.56e-052138231507096
Pubmed

Lipid efflux by the ATP-binding cassette transporters ABCA1 and ABCG1.

ABCA1 ABCG1

1.56e-052138216798073
Pubmed

Bacterial lipopolysaccharide induces expression of ABCA1 but not ABCG1 via an LXR-independent pathway.

ABCA1 ABCG1

1.56e-052138212032171
Pubmed

First case of combined small-cell lung cancer with adenocarcinoma harboring EML4-ALK fusion and an exon 19 EGFR mutation in each histological component.

EML4 EGFR

1.56e-052138223154565
Pubmed

EGFR signaling to p120-catenin through phosphorylation at Y228.

EGFR CTNND1

1.56e-052138214996911
Pubmed

ATP-binding cassette transporter G1 and high-density lipoprotein promote endothelial NO synthesis through a decrease in the interaction of caveolin-1 and endothelial NO synthase.

ABCA1 ABCG1

1.56e-052138220798376
Pubmed

Proteasomal inhibition promotes ATP-binding cassette transporter A1 (ABCA1) and ABCG1 expression and cholesterol efflux from macrophages in vitro and in vivo.

ABCA1 ABCG1

1.56e-052138221817095
Pubmed

Human endothelial cells of the placental barrier efficiently deliver cholesterol to the fetal circulation via ABCA1 and ABCG1.

ABCA1 ABCG1

1.56e-052138219168441
Pubmed

EGFR nuclear translocation modulates DNA repair following cisplatin and ionizing radiation treatment.

EGFR PRKDC

1.56e-052138221266349
Pubmed

ABC transporter genes and risk of type 2 diabetes: a study of 40,000 individuals from the general population.

ABCA1 ABCG1

1.56e-052138223139370
Pubmed

The implication of adipocyte ATP-binding cassette A1 and G1 transporters in metabolic complications of obesity.

ABCA1 ABCG1

1.56e-052138231172973
Pubmed

Disrupted cholesterol metabolism promotes age-related photoreceptor neurodegeneration.

ABCA1 ABCG1

1.56e-052138229946056
Pubmed

Unsaturated fatty acids repress expression of ATP binding cassette transporter A1 and G1 in RAW 264.7 macrophages.

ABCA1 ABCG1

1.56e-052138222209005
Pubmed

Up-regulation of microRNA-135 or silencing of PCSK6 attenuates inflammatory response in preeclampsia by restricting NLRP3 inflammasome.

NLRP3 PCSK6

1.56e-052138234301174
Pubmed

ABC1 promotes engulfment of apoptotic cells and transbilayer redistribution of phosphatidylserine.

ABCA1 ADGRE1

1.56e-052138210878804
Pubmed

Multiple-state reactions between the epidermal growth factor receptor and Grb2 as observed by using single-molecule analysis.

GRB2 EGFR

1.56e-052138217991782
Pubmed

Grb2/Ash binds directly to tyrosines 1068 and 1086 and indirectly to tyrosine 1148 of activated human epidermal growth factor receptors in intact cells.

GRB2 EGFR

1.56e-05213827527043
Pubmed

Expression of ABC transporters during syncytialization in preeclampsia.

ABCA1 ABCG1

1.56e-052138235124425
Pubmed

Angiotensin-(1-7) upregulates expression of adenosine triphosphate-binding cassette transporter A1 and adenosine triphosphate-binding cassette transporter G1 through the Mas receptor through the liver X receptor alpha signalling pathway in THP-1 macrophages treated with angiotensin-II.

ABCA1 ABCG1

1.56e-052138225225013
Pubmed

p120-catenin down-regulation and epidermal growth factor receptor overexpression results in a transformed epithelium that mimics esophageal squamous cell carcinoma.

EGFR CTNND1

1.56e-052138225529795
Pubmed

Recent advances in the regulation of ABCA1 and ABCG1 by lncRNAs.

ABCA1 ABCG1

1.56e-052138233545111
Pubmed

Phosphorylation of human DNA ligase I regulates its interaction with replication factor C and its participation in DNA replication and DNA repair.

RFC1 LIG1

1.56e-052138219223468
Pubmed

ABCA1- and ABCG1-mediated cholesterol efflux capacity of cerebrospinal fluid is impaired in Alzheimer's disease.

ABCA1 ABCG1

1.56e-052138231167810
Pubmed

Activation of the epidermal growth factor (EGF) receptor induces formation of EGF receptor- and Grb2-containing clathrin-coated pits.

GRB2 EGFR

1.56e-052138216382132
Pubmed

[Regulation of ABCA1 and ABCG1 gene expression in the intraabdominal adipose tissue].

ABCA1 ABCG1

1.56e-052138227420620
Pubmed

Reduced expression of ATP-binding cassette transporter G1 increases cholesterol accumulation in macrophages of patients with type 2 diabetes mellitus.

ABCA1 ABCG1

1.56e-052138218490524
Pubmed

Course of Brugia malayi infection in C57BL/6J NOS2 +/+ and -/- mice.

PRKDC NOS2

1.56e-052138211426950
Pubmed

Placental ABCA1 and ABCG1 expression in gestational disease: Pre-eclampsia affects ABCA1 levels in syncytiotrophoblasts.

ABCA1 ABCG1

1.56e-052138223880356
Pubmed

Progression of pulmonary tuberculosis and efficiency of bacillus Calmette-Guérin vaccination are genetically controlled via a common sst1-mediated mechanism of innate immunity.

PRKDC NOS2

1.56e-052138217982083
Pubmed

The human GRB2 and Drosophila Drk genes can functionally replace the Caenorhabditis elegans cell signaling gene sem-5.

GRB2 EGFR

1.56e-05213828305738
Pubmed

Unsaturated fatty acids suppress the expression of the ATP-binding cassette transporter G1 (ABCG1) and ABCA1 genes via an LXR/RXR responsive element.

ABCA1 ABCG1

1.56e-052138216730733
Pubmed

Small discoidal pre-beta1 HDL particles are efficient acceptors of cell cholesterol via ABCA1 and ABCG1.

ABCA1 ABCG1

1.56e-052138219839639
Pubmed

Radiation-induced epidermal growth factor receptor nuclear import is linked to activation of DNA-dependent protein kinase.

EGFR PRKDC

1.56e-052138216000298
Pubmed

Detection of Grb-2-related adaptor protein gene (GRAP) and peptide molecule in salivary glands of MRL/lpr mice and patients with Sjögren's syndrome.

GRAPL GRAP

1.56e-052138215174222
Pubmed

Activation of epidermal growth factor receptor signals induction of nitric oxide synthase-2 in human optic nerve head astrocytes in glaucomatous optic neuropathy.

EGFR NOS2

1.56e-052138212828935
Pubmed

Activated platelets rescue apoptotic cells via paracrine activation of EGFR and DNA-dependent protein kinase.

EGFR PRKDC

1.56e-052138225210793
Pubmed

Phosphorylation of serine 51 regulates the interaction of human DNA ligase I with replication factor C and its participation in DNA replication and repair.

RFC1 LIG1

1.56e-052138222952233
Pubmed

Recruitment of the adaptor protein Grb2 to EGFR tetramers.

GRB2 EGFR

1.56e-052138224697349
Pubmed

Role of ABCG1 and ABCA1 in regulation of neuronal cholesterol efflux to apolipoprotein E discs and suppression of amyloid-beta peptide generation.

ABCA1 ABCG1

1.56e-052138217121837
Pubmed

Phytosterols differentially influence ABC transporter expression, cholesterol efflux and inflammatory cytokine secretion in macrophage foam cells.

ABCA1 ABCG1

1.56e-052138221111593
Pubmed

Efflux of sphingomyelin, cholesterol, and phosphatidylcholine by ABCG1.

ABCA1 ABCG1

1.56e-052138216702602
Pubmed

Coexistence of foam cells and hypocholesterolemia in mice lacking the ABC transporters A1 and G1.

ABCA1 ABCG1

1.56e-052138217967783
Pubmed

High glucose, unsaturated and saturated fatty acids differentially regulate expression of ATP-binding cassette transporters ABCA1 and ABCG1 in human macrophages.

ABCA1 ABCG1

1.56e-052138219287193
Pubmed

Grb2-related adaptor protein GRAP is a novel regulator of liver fibrosis.

GRAPL GRAP

1.56e-052138237343720
Pubmed

Differential regulation of ABCA1 and ABCG1 gene expressions in the remodeling mouse hippocampus after entorhinal cortex lesion and liver-X receptor agonist treatment.

ABCA1 ABCG1

1.56e-052138224661912
Pubmed

DNA-ligase IV and DNA-protein kinase play a critical role in deficient caspases activation in apoptosis-resistant cancer cells by using doxorubicin.

LIG4 PRKDC

1.56e-052138218508926
Pubmed

Effect of insulin insufficiency on ultrastructure and function in skeletal muscle.

ABCA1 ABCG1

1.56e-052138238124345
Pubmed

[Role of the ABC transporters A1 and G1, key reverse cholesterol transport proteins, in atherosclerosis].

ABCA1 ABCG1

1.56e-052138227239842
Pubmed

HDL and Glut1 inhibition reverse a hypermetabolic state in mouse models of myeloproliferative disorders.

ABCA1 ABCG1

1.56e-052138223319699
Pubmed

The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling.

GRB2 EGFR

1.56e-05213821322798
Pubmed

Live-cell fluorescence imaging reveals high stoichiometry of Grb2 binding to the EGF receptor sustained during endocytosis.

GRB2 EGFR

1.56e-052138224259669
Pubmed

Cellular cholesterol regulates ubiquitination and degradation of the cholesterol export proteins ABCA1 and ABCG1.

ABCA1 ABCG1

1.56e-052138224500716
Pubmed

Identification of UHRF1/2 as new N-methylpurine DNA glycosylase-interacting proteins.

NOC2L NCBP1 GNL2 UHRF1

1.58e-0538138423537643
InteractionH3C1 interactions

SFMBT1 VRK1 ATRX KDM5A AHCTF1 GRB2 DIDO1 CHD1 BRMS1L OLA1 RFC1 NEB ESCO1 MSH6 TAF3 EGFR POP1 GNL2 UHRF1 PRKDC PTCD3

6.73e-0790113621int:H3C1
InteractionH3-3A interactions

VRK1 ATRX KDM5A EML4 AHCTF1 DIDO1 NCBP1 CHD1 RO60 RFC1 MSH6 TAF3 UBE2H EGFR GNL2 UHRF1 PRKDC ZFP82 FOXC1

6.93e-0774913619int:H3-3A
InteractionPOLD1 interactions

ATRX NCBP1 CHD1 RFC1 LIG1 TAF3 UBE2H EGFR SIPA1L1 STIP1 PRKDC CTNND1

3.12e-0633713612int:POLD1
InteractionSERTAD4 interactions

CBLL2 PPP2R2B PPP2R2C EGFR

7.11e-06191364int:SERTAD4
InteractionKRT81 interactions

KRT26 KRT27 GRB2 NOS2 KRT25

2.88e-05531365int:KRT81
InteractionH3C3 interactions

VRK1 ATRX KDM5A AHCTF1 DIDO1 NCBP1 CHD1 RFC1 MSH6 GNL2 UHRF1 ZFP82 FOXC1

3.14e-0549513613int:H3C3
InteractionPTEN interactions

SFMBT1 MAN1A1 ATRX NOC2L PSD3 GRB2 ITGA6 NCBP1 MSH6 QRFPR ARAP3 TXNDC5 ST8SIA6 EGFR POP1 CRYBG1 STIP1 PRKDC

5.40e-0592913618int:PTEN
InteractionNPM1 interactions

VRK1 MYO5A NOC2L AHCTF1 GRB2 DIDO1 CHD1 RO60 RFC1 NEB DHX30 TAF3 UBE2H EGFR POP1 OSBPL1A GNL2 STIP1 PRKDC NOS2 PTCD3

5.47e-05120113621int:NPM1
InteractionCLNK interactions

SFMBT1 GRB2 ARAP3 EGFR

6.16e-05321364int:CLNK
InteractionSMC2 interactions

ATRX EML4 RO60 RFC1 MSH6 LIG4 UBE2H EGFR MAP7D2 STIP1

6.96e-0532313610int:SMC2
InteractionH2BC21 interactions

VRK1 ATRX NOC2L AHCTF1 DIDO1 FAM47B RFC1 NEB ESCO1 MSH6 C2CD3 TLN1 UHRF1 CRYBG1 PRKDC

7.36e-0569613615int:H2BC21
InteractionRUVBL2 interactions

CLTCL1 EML4 TTI2 GRB2 NCBP1 RO60 LIG1 LIG4 UBE2H EGFR FDFT1 STIP1 PRKDC NOS2

7.40e-0561613614int:RUVBL2
InteractionLRRC31 interactions

MYO5A DHX30 MSH6 ARAP3 EGFR CRYBG1 EIF2AK4 PRKDC

7.74e-052051368int:LRRC31
GeneFamilyDNA ligases|Nucleotide excision repair

LIG1 LIG4

7.49e-0539121247
GeneFamilyCD molecules|Adhesion G protein-coupled receptors, subfamily E

ADGRE2 ADGRE1

2.48e-045912915
GeneFamilyKeratins, type I

KRT26 KRT27 KRT25

3.69e-0428913608
GeneFamilyPHD finger proteins

KDM5A DIDO1 TAF3 UHRF1

1.10e-039091488
GeneFamilyATP binding cassette subfamily A

ABCA1 ABCA13

2.19e-0314912805
GeneFamilyWD repeat domain containing|Protein phosphatase 2 regulatory subunits

PPP2R2B PPP2R2C

2.52e-0315912696
CoexpressionSRC_UP.V1_DN

UTS2R ARL15 LIG1 NYNRIN POP1 SERPINB2 PAK3 UHRF1 ADGRE1

2.72e-071701369M2713
CoexpressionGSE37301_CD4_TCELL_VS_RAG2_KO_NK_CELL_DN

VRK1 EML4 GPAT3 NEB CCDC112 LIG4 TLN1 OSBPL1A

4.72e-061801368M8906
CoexpressionVEGF_A_UP.V1_DN

VRK1 MYO5A NOC2L PSD3 POP1 SERPINB2 STIP1 IL1RL1

7.87e-061931368M2675
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

SFMBT1 VRK1 RNGTT ATRX KDM5A AHCTF1 PSD3 ITGA6 CHD1 MED13L MSH6 C2CD3 EGFR MTIF2 SIPA1L1 SERPINB2

9.85e-0685613616M4500
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_2500_k-means-cluster#4

RNGTT ATRX KDM5A DIDO1 LCP1 ZNF250 LIG1 TAF3 MTIF2 SIPA1L1 POP1 GNL2 PAK3 MAP7D2 EIF2AK4

5.47e-0659513415Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_2500_K4
CoexpressionAtlasDevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_top-relative-expression-ranked_1000

SFMBT1 ATRX KDM5A AHCTF1 DIDO1 CHD1 OLA1 RFC1 SENP8 DHX30 C2CD3 RSAD2 TXNDC5 INMT MAP7D2 CRYBG1 MAPK4

1.21e-0580113417gudmap_developingKidney_e15.5_ureter tip_1000_flank cortic collct
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_k-means-cluster#5_top-relative-expression-ranked_1000

MYO5A PSD3 NCBP1 CHD1 RO60 BRMS1L FOCAD EGFR OSBPL1A PAK3 ANTXR1 ZFP82

5.19e-0547813412gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_1000_k5
ToppCellNeuronal-Excitatory-eA(LAMP5_LINC00507)-LTK---L2|Neuronal / cells hierarchy compared to all cells using T-Statistic

MAN1A1 THSD7A NHSL2 RGS12 ARL4A SIPA1L1 PCSK6 MAPK4

2.27e-0720013986ebdae4438bc64c6620416f64a7e22fbca2664bf
ToppCellNeuronal-Excitatory-eA(LAMP5_LINC00507)-LTK-|Neuronal / cells hierarchy compared to all cells using T-Statistic

MAN1A1 THSD7A NHSL2 RGS12 ARL4A SIPA1L1 PCSK6 MAPK4

2.27e-072001398081ca331b56f85167acfc73af9d2e91f398f8c4d
ToppCellNeuronal-Excitatory-eA(LAMP5_LINC00507)-LTK--|Neuronal / cells hierarchy compared to all cells using T-Statistic

MAN1A1 THSD7A NHSL2 RGS12 ARL4A SIPA1L1 PCSK6 MAPK4

2.27e-07200139866e2f3e2e9063f17b47621120eb6009405f69e7e
ToppCellNeuronal-Excitatory-eA(LAMP5_LINC00507)-LTK|Neuronal / cells hierarchy compared to all cells using T-Statistic

MAN1A1 THSD7A NHSL2 RGS12 ARL4A SIPA1L1 PCSK6 MAPK4

2.27e-072001398940892bea41fde567f138a896d151acccef03a6a
ToppCell3'_v3-bone_marrow-Myeloid_Mac-Erythrophagocytic_macrophages|bone_marrow / Manually curated celltypes from each tissue

ABCA1 PSD3 HNMT ABCG1 NYNRIN OSBPL1A CTNND1

1.60e-061801397daf69a548ed7c6f285a6adcff00f99aa22f9d6a5
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_3|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ANKRD31 GPAT3 TLR10 PPP2R2B FDFT1 FADS2 CTNND1

1.85e-0618413971c56378b3888c46258d446b47de4d6282fe74b0d
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_3|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ANKRD31 GPAT3 TLR10 PPP2R2B FDFT1 FADS2 CTNND1

1.85e-061841397a45980306c4e697a2703bed72a7b48fb23d942f4
ToppCell5'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NPR1 LRTM1 ITGA6 ARL4A ABCG1 GRAPL FOXC1

1.99e-061861397055cc23c4db9aad2d6c62e62c8e58bfe5047c6b1
ToppCellFetal_29-31_weeks-Immune-interstitial_macrophage_(C1Q_positive)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ABCA1 MYO5A GPAT3 GRB2 ADGRE2 ABCG1 SIPA1L1

2.13e-0618813973be2d50148daa4eddddc2c7f269f45c97f7e4931
ToppCellRA-08._Macrophage|World / Chamber and Cluster_Paper

MYO5A GRB2 LCP1 ADGRE2 NLRP3 SIPA1L1 TET3

2.54e-0619313975fd22db1825d105709fcc0aa4955c99a117e3c82
ToppCellPCW_13-14-Endothelial-Endothelial_immature-endo_immature4_(5)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

NPR1 ITGA6 THSD7B ABCG1 ST8SIA6 CRYBG1 GRAP

2.54e-06193139701c71aa48875b5ad6c50cc810a72862e72f26ad0
ToppCellPCW_13-14-Endothelial-Endothelial_mature-endo_venous_(13)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

NPR1 NHSL2 ITGA6 ARL4A ABCG1 ST8SIA6 FOXC1

2.54e-06193139784d1c1b7d3a1cb80f175527e3c89a2c3da7657f7
ToppCellPCW_13-14-Endothelial-Endothelial_immature-endo_immature_arterial1_(12)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

NPR1 ITGA6 THSD7B ABCG1 CRYBG1 NOS2 GRAP

2.62e-06194139732ba2cf9b8726bc3c6e9dc24b54d22ff188bb12b
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CRHBP QRFPR ABCG1 ARAP3 ST8SIA6 GRAPL GRAP

2.62e-061941397ad6c04ad0621689e3bf4c94ccd6e60653bbd02c7
ToppCellPCW_10-12-Endothelial-Endothelial_immature-endo_immature4_(5)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

NPR1 ITGA6 THSD7B ABCG1 ST8SIA6 CRYBG1 GRAP

2.62e-06194139753a5e8863d79a052dff0758f389be5ac3883c721
ToppCell3'_v3-Lung-Hematopoietic_progenitors-Cycling_pre-Myeloid-2|Lung / Manually curated celltypes from each tissue

GPAT3 LIG1 SERPINB2 FADS2 UHRF1 CDK3

1.24e-05163139647300dec94dc66e965bf71fafff0a9fd24fae968
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

EML4 AHCTF1 IGSF22 TTC21B CRYBG1 PRKDC

1.43e-05167139683969c36ac44b96afc9aa09400a99fa2b487f7ff
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.0.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA1 MYO5A GRB2 LCP1 ADGRE2 TET3

1.63e-051711396b520d4d5620cac08315e4cbb7e796c5e9e233060
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THSD7A GPAT3 PSD3 ITGA6 ARL15 ST8SIA6

1.86e-05175139677c16e615c0fb9c83f29d7e0a547be72635fac81
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes-Non-classical_monocytes_L.1.2.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MYO5A LCP1 ADGRE2 NLRP3 TLR10 TLN1

2.05e-051781396aa9f68a66e292f331faef881bbd0d028f0f2b0c5
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THSD7A GPAT3 PSD3 ITGA6 THSD7B ARL15

2.11e-051791396e6ae070b4c52ba08167c7d64ea4cfbac0454c1bf
ToppCell10x5'v1-week_12-13-Mesenchymal_osteo-stroma-osteochondral_precursor|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

UTS2R THSD7B EGFR ANTXR1 MMP11 FOXC1

2.11e-05179139698c0c5c8034ae8a4b3ceea7fd1d0386ee5f89d09
ToppCellTCGA-Head_and_Esophagus-Primary_Tumor-Head_and_Neck_Carcinoma-Squamous_Cell_Carcinoma-4|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

KDM5A THSD7B MSH6 FADS2 ANTXR1 CDON

2.18e-051801396886ebaf9cf8992e8dd13fca799a1d1a2a9ce73d8
ToppCellE16.5-samps-Endothelial-Immature_fetal_endothelial-Intermediate_Endothelial|E16.5-samps / Age Group, Lineage, Cell class and subclass

NPR1 ADGRE2 ABCG1 ARAP3 NOS2 GRAP

2.32e-051821396fec1caf867b1dc87b24504d895ee1a27df78062e
ToppCellBasal|World / shred by cell class for mouse tongue

ABCA1 ITGA6 ARL4A PPP2R2C TLN1 ANTXR1

2.39e-051831396c6729a207526ff4aa48176207b9353176f631fea
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.5.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA1 ADGRE2 NLRP3 SIPA1L1 SERPINB2 TET3

2.47e-051841396d1ea2b60fb1ca1a0b809d131310c43903a9e84ce
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NHSL2 RGS12 ARL4A EGFR SIPA1L1 MAPK4

2.47e-05184139630fddbc9696476d4d7f08e53f84ea994a4ed873a
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NPR1 THSD7A ABCA13 HUNK EGFR FOXC1

2.47e-051841396da06ff24ee2b2cf4715fdfce43030b2da9e0aaf8
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NHSL2 RGS12 ARL4A EGFR SIPA1L1 MAPK4

2.47e-05184139696926efa220f03d0787322c9519bb9e8f64f74d0
ToppCellChildren_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

ABCA1 MAN1A1 MYO5A PSD3 HNMT CRHBP

2.54e-0518513968207f9eff113eed429e961748c6b17d672a13b33
ToppCellPCW_13-14-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

NPR1 ARL4A ABCG1 PCSK6 GRAPL GRAP

2.54e-0518513963be9e05b929ac4d956b1d53284072f668a6c1959
ToppCellPCW_13-14-Endothelial-Endothelial_mature-lymphatic|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

NPR1 ARL4A ABCG1 PCSK6 GRAPL GRAP

2.54e-051851396c3dd64a726cb8a1fe048683c266b7532a714a52e
ToppCell3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Cycling_pre-Myeloid-2|lymph-node_spleen / Manually curated celltypes from each tissue

ARAP3 OSBPL1A SERPINB2 FADS2 UHRF1 TET3

2.70e-0518713963c10b8501226c69d71bcd99dc1c064a3c2154f87
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

EML4 AHCTF1 CHD1 MED13L UBE2H DDHD1

2.78e-051881396ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MAN1A1 THSD7A MYO5A PSD3 ARL15 CRYBG1

2.78e-05188139658ccb31cdf43167872ef0fc737e6f9c51ee2e060
ToppCellfacs-Skin-Telogen-3m-Epithelial-Basal_IFE|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA6 RGS12 PPP2R2C ABCG1 SERPINB2 ANTXR1

2.78e-0518813968cc927b4c51d982fdafa04dc7393617ad9bb220e
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

NPR1 ITGA6 ARL4A PCSK6 GRAPL GRAP

2.87e-0518913960d18ea72bd58d32a8ab9a61cf97f5786642f804b
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NPR1 ABCA13 HUNK ABCG1 EGFR FOXC1

2.87e-051891396904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Artery|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

THSD7A ITGA6 ARL15 QRFPR ARAP3 ST8SIA6

2.87e-051891396c45734970036e6d28d5e3fe7c9458fae38a3f624
ToppCellFetal_29-31_weeks-Immune-monocyte-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

GPAT3 GRB2 ADGRE2 NLRP3 SIPA1L1 CRYBG1

2.95e-051901396ad297172a74a80ed5c10f921e15efd1da0fd2d6b
ToppCellChildren_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)|Children_(3_yrs) / Lineage, Cell type, age group and donor

ABCA1 MAN1A1 MYO5A PSD3 CRHBP NLRP3

2.95e-051901396f573fef3762a30c38cf8fa7f45df0ffbb49dc873
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THSD7A PSD3 ITGA6 HUNK ARL15 CRYBG1

2.95e-051901396b3bccf4dd95e986db3cee324a6737f5fcc22e8e5
ToppCellPBMC-Severe-cDC_12|Severe / Compartment, Disease Groups and Clusters

ITGA6 LIG1 MSH6 FADS2 UHRF1 PRKDC

2.95e-05190139684ee185939bdefb10705b621a70da27701eadcee
ToppCellCOPD-Myeloid-cDC2|COPD / Disease state, Lineage and Cell class

GPAT3 ADGRE2 NLRP3 SIPA1L1 CRYBG1 EIF2AK4

3.04e-0519113962af6e4a6bd1f2193ece2131c3b7d976dd23a6966
ToppCellCOPD-Myeloid-cDC2|World / Disease state, Lineage and Cell class

GPAT3 ADGRE2 NLRP3 SIPA1L1 CRYBG1 EIF2AK4

3.04e-0519113964e4887175200a57e1b041f2f131e3df774df3509
ToppCellLPS-antiTNF-Endothelial-Endothelial-Artery|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

THSD7A ITGA6 ARL15 QRFPR ARAP3 ST8SIA6

3.04e-0519113964b3d5157344dbfbf4fab518611cd9fa37fac7bd9
ToppCellCOVID-19-Heart-EC_(POSTN)|Heart / Disease (COVID-19 only), tissue and cell type

NPR1 THSD7A NHSL2 ST8SIA6 SIPA1L1 FOXC1

3.13e-051921396c0c34785a7bdf461722029b322e9184e3d9b3c26
ToppCellfacs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-25|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NPR1 MAN1A1 PPP2R2B EGFR PCSK6 ANTXR1

3.13e-05192139630cefa0990ba1f379f350bfbf994a78db145075e
ToppCellRV-08._Macrophage|World / Chamber and Cluster_Paper

MAN1A1 MYO5A GRB2 HNMT SIPA1L1 TET3

3.13e-051921396a1b5dc5beb97a23729b97b54fb4574d10d8fbfb3
ToppCellCOVID-19-kidney-AQP1+PLVAP+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

NPR1 THSD7A ARL15 CRHBP ABCG1 GRAPL

3.13e-05192139627ff3621e177e7932dd44dd6baa81551ea75a874
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

THSD7A PSD3 ITGA6 HUNK ARL15 CRYBG1

3.13e-051921396f7e7491426bbd6ed29a465b58bf67acb93dbb90a
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA6 ADGRE2 RGS12 ARL4A FOXC1 GRAP

3.13e-0519213969ae05db5bfb8b9d3935c0328e6f2d489d2b1ebfd
ToppCellAdult-Immune-alveolar_macrophage_(MARCO_positive)-D175|Adult / Lineage, Cell type, age group and donor

ABCA1 MYO5A PDSS1 EML4 GRB2 ARL15

3.13e-051921396733491e932350e3c216a626cc49c3cd3fe970a82
ToppCellEndothelial|World / shred on cell class and cell subclass (v4)

NPR1 ITGA6 ADGRE2 RGS12 ARAP3 GRAP

3.13e-0519213962b13cca5c4b58628dbbbb356859632dba66d43f9
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA6 ADGRE2 RGS12 ARL4A FOXC1 GRAP

3.13e-051921396a116db7dec495e5a0ba9c7537057cd1e567d7885
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA6 ADGRE2 RGS12 ARL4A FOXC1 GRAP

3.13e-05192139666defad13bd8e79319741e43ddb056841710b1d7
ToppCellfacs-Aorta-Heart-3m-Mesenchymal|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAN1A1 CPT1A EGFR PCSK6 ANTXR1 CDON

3.13e-0519213960dc1f46e40346ed0b286e53b106a812441575100
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

THSD7A SCG5 THSD7B CRHBP RGS12 EGFR

3.22e-0519313969f9eb241b0b82a6f12de6921c3acf6fed7cf65bb
ToppCellPCW_07-8.5-Endothelial-Endothelial_immature-endo_immature_arterial1_(12)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

NPR1 THSD7B PCSK6 CRYBG1 NOS2 GRAP

3.22e-051931396d338a7c0585b69947c37f44aa0381619493e31ea
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA6 ADGRE2 RGS12 ARL4A FOXC1 GRAP

3.22e-051931396e4b440d50ae7391b26924778be6d9d53e0692449
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA6 ADGRE2 RGS12 ARL4A FOXC1 GRAP

3.22e-051931396e523dc5751f6fdcd4fc1a62b1eecd43f6ae79da9
ToppCellRV-08._Macrophage|RV / Chamber and Cluster_Paper

MAN1A1 MYO5A GRB2 LCP1 SIPA1L1 TET3

3.22e-05193139612bf98a280f87e4d8f0c6887dfc855da72e47ac1
ToppCellControl-Myeloid-ncMonocyte|Myeloid / Disease state, Lineage and Cell class

ABCA1 CHD1 MED13L ADGRE2 SIPA1L1 ADGRE1

3.22e-0519313963479c01aaae7afd7e02d00e0cb21951c0106a0fd
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA6 ADGRE2 RGS12 ARL4A FOXC1 GRAP

3.22e-0519313961772f2ac217727de63c4a9303881b3a19a6bb0f0
ToppCellPCW_07-8.5-Endothelial-Endothelial_immature-endo_immature4_(5)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

NPR1 THSD7B ABCG1 ST8SIA6 PCSK6 GRAP

3.22e-05193139672d20ee257149b238016b44d183ce3fc24b8f621
ToppCellFetal_29-31_weeks-Immune-alveolar_macrophage_(MARCO_positive)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

GPAT3 GRB2 ADGRE2 NLRP3 ABCG1 SIPA1L1

3.32e-0519413963043f6230fa723037c8cf7123f611ae847b39fd4
ToppCellPCW_13-14-Endothelial-Endothelial_mature-endo_capillary_(2)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

NPR1 ITGA6 THSD7B ABCG1 ST8SIA6 CRYBG1

3.32e-0519413963c31ac44e8cf4eca3ba7b8bfc05ad3e96a970956
ToppCellPCW_10-12-Endothelial-Endothelial_mature-endo_venous_(13)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

NPR1 ITGA6 THSD7B ARL4A ST8SIA6 FOXC1

3.32e-051941396efd5efed060edb7f24d59600981bb60ec28ac2ef
ToppCellTransplant_Alveoli_and_parenchyma-Immune-Neutrophils|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X

NHSL2 CHD1 ADGRE2 NLRP3 SIPA1L1 SERPINB2

3.32e-05194139628571cf24b8a1d0ffb716167b977d420868cc874
ToppCellLA-08._Macrophage|World / Chamber and Cluster_Paper

MAN1A1 MYO5A GRB2 LCP1 SIPA1L1 TET3

3.32e-051941396c1805572bcc11b1cd29083329d7b5911489fb758
ToppCellRA-08._Macrophage|RA / Chamber and Cluster_Paper

MYO5A GRB2 LCP1 ADGRE2 SIPA1L1 TET3

3.32e-051941396ac26e5c71d5069622de72fa25a9c920887ac2c19
ToppCellPCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_dendritic-im_dendritic_(11)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

GPAT3 LCP1 ADGRE2 NLRP3 TLR10 CRYBG1

3.42e-0519513964387e27d2288fb46a9ed110464542a4aea402358
ToppCellChildren_(3_yrs)-Immune-alveolar_macrophage_(MARCO_positive)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ABCA1 EML4 GRB2 DDHD1 OSBPL1A TET3

3.42e-0519513969d649ac7d2af313481069c95349efc0c68449e2b
ToppCellCOVID-19-lung-Macrophage_CD163hi_MERTKhi|lung / Disease (COVID-19 only), tissue and cell type

ABCA1 MYO5A GRB2 ADGRE2 SIPA1L1 TET3

3.42e-051951396148fff8c3c9ba45ec36e98dff1be57e3f8294506
ToppCellControl-Myeloid-ncMonocyte|Control / Disease state, Lineage and Cell class

ABCA1 CHD1 MED13L ADGRE2 SIPA1L1 ADGRE1

3.42e-051951396fcb05948e7480dc53f06f3fc9b9c3fc129874edd
ToppCellLA-08._Macrophage|LA / Chamber and Cluster_Paper

MAN1A1 MYO5A GRB2 LCP1 SIPA1L1 TET3

3.42e-0519513965e1d5bdb8874091f5a2b1d0a8cc9008165718a97
ToppCellPCW_10-12-Endothelial-Endothelial_immature-endo_immature_arterial1_(12)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

NPR1 ITGA6 THSD7B ABCG1 NOS2 GRAP

3.42e-0519513963826bfafe85f8aa9a508202ceb2b02e81b090498
ToppCellPCW_07-8.5-Endothelial|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

NPR1 THSD7B ABCG1 ST8SIA6 PCSK6 GRAP

3.42e-051951396f2cc94d5e1652203ca38bea57f37d3deec73ef04
ToppCellPCW_13-14-Endothelial-Endothelial_mature|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

NPR1 ITGA6 THSD7B ABCG1 ST8SIA6 CRYBG1

3.42e-05195139631353269591c9eee84872838e91995d4a035da46
ToppCellPCW_10-12-Endothelial-Endothelial_mature-endo_capillary_(2)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

NPR1 ITGA6 THSD7B ABCG1 ST8SIA6 GRAP

3.52e-0519613962a2a93b89dcb98043cb1f8b422ac8c55e2edc37b
ToppCellPCW_13-14-Endothelial|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

NPR1 ITGA6 THSD7B ABCG1 ST8SIA6 GRAP

3.52e-0519613967286de29a34e13834cd6347c67a1443897fa4ade
ToppCellPCW_13-14-Endothelial-Endothelial_cycling-endo_proliferating1_(10)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

NPR1 ITGA6 ABCG1 ST8SIA6 CRYBG1 GRAP

3.52e-051961396b826dce5b3daa8eb3d4a530b9564de58d9ce3767
ToppCellPCW_10-12-Endothelial-Endothelial_immature-endo_immature1_(0)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

NPR1 ITGA6 THSD7B ABCG1 ST8SIA6 GRAP

3.52e-05196139629ed8b1c4cd730db8632fde6eece404f1883a86d
ToppCellTransplant_Alveoli_and_parenchyma-Immune-Neutrophils|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

CHD1 LCP1 ADGRE2 NLRP3 SIPA1L1 SERPINB2

3.52e-051961396376c5a459a484205fbb0db34936e4a6146d1f622
ToppCellPCW_10-12-Endothelial-Endothelial_immature|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

NPR1 ITGA6 THSD7B ABCG1 ST8SIA6 GRAP

3.52e-051961396c65b8c7ea34a21897c390e6fb42ee8ca41e9c976
ToppCellCOVID-19-lung-Macrophage_CD163hi_MERTKhi|COVID-19 / Disease (COVID-19 only), tissue and cell type

ABCA1 MYO5A GRB2 LCP1 ADGRE2 TET3

3.52e-0519613967026c1fc33425e5476063d17c79e4b79356a9e01
ToppCellPCW_10-12-Endothelial-Endothelial_immature-endo_immature_venous_(4)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

NPR1 ITGA6 THSD7B ABCG1 ST8SIA6 GRAP

3.52e-05196139681278e696d823744267d6315c4d42799c4ea0b2c
ToppCellmild_COVID-19_(asymptomatic)|World / disease group, cell group and cell class (v2)

ABCA1 MED13L ADGRE2 RSAD2 CTNND1 TET3

3.52e-0519613968cb3dcb3e5732f4bb060c87ca339b8997a1a8cd4
ToppCellPCW_13-14-Endothelial-Endothelial_immature|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

NPR1 ITGA6 THSD7B ABCG1 ST8SIA6 GRAP

3.52e-0519613969ed96085f0acce07bf2f8d4cc212cc50e613be0c
ToppCellPCW_10-12-Endothelial|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

NPR1 ITGA6 THSD7B ABCG1 ST8SIA6 GRAP

3.52e-0519613962c60dcf9132ee156f25b349e2ac5313709def4f6
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA1 MYO5A GRB2 LCP1 ADGRE2 SIPA1L1

3.62e-0519713968af4a1e35ce9fb4ea3d26ab619599efb7eac43a5
ToppCellPCW_13-14-Endothelial-Endothelial_immature-endo_immature1_(0)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

NPR1 ITGA6 THSD7B ABCG1 ST8SIA6 GRAP

3.62e-0519713964e9221cb02122aed2981c3c9157e847a3710e323
ToppCellSepsis-ICU-SEP-Lymphocyte-T/NK-NK_CD56bright|ICU-SEP / Disease, condition lineage and cell class

SCG5 ACSM1 LIG1 C1orf198 PAK3 MMP11

3.62e-051971396c187e3fc2160b0165eb039cf09a6e621016068b7
ToppCell3'-Broncho-tracheal-Immune_Myeloid|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA1 GRB2 LCP1 ADGRE2 NLRP3 TLN1

3.62e-051971396d568354aff89ac84dd06360f19100ef578a041ed
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GPAT3 CHD1 LCP1 ADGRE2 NLRP3 SERPINB2

3.62e-0519713960c059476a8cdc6ac71a01d9c414295177f45f8de
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

GPAT3 GRB2 LCP1 ADGRE2 NLRP3 SIPA1L1

3.62e-0519713961eb9ff8467118b943b5d443cb996168e1e1206b5
ToppCellPCW_13-14-Endothelial-Endothelial_cycling-endo_proliferating3_(3)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

NPR1 ITGA6 ABCG1 ST8SIA6 CRYBG1 GRAP

3.62e-051971396aedc1e3ed6b558bf2f7649919f43049f8348ab85
ToppCellPCW_10-12-Endothelial-Endothelial_cycling|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

NPR1 ITGA6 THSD7B ABCG1 ST8SIA6 GRAP

3.72e-051981396eac26ed95b4a4343a5dfe1fbecef9374e5947884
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GPAT3 CHD1 LCP1 ADGRE2 NLRP3 SERPINB2

3.72e-0519813964b6767bd6fd4bd43eed18fd4a34c20923fa795da
ToppCellCOVID-19_Mild|World / Disease condition and Cell class

GRB2 CHD1 MED13L LCP1 RSAD2 TLN1

3.72e-05198139661ceb2245b6cb58e308b999a61d218c89dbc615e
DrugMeropenem [96036-03-2]; Up 200; 10.4uM; MCF7; HT_HG-U133A

MAN1A1 EML4 ITGA6 MANEA TNFRSF10B LCP1 RGS12 AP4E1 MSH6 LIG4 EGFR CDK3

2.11e-09197134127180_UP
DrugBromocryptine mesylate [22260-51-1]; Down 200; 5.4uM; MCF7; HT_HG-U133A

MAN1A1 ATRX DIDO1 TNFRSF10B ARL15 ZNF250 AP4E1 EGFR GNL2

2.60e-0619713491507_DN
Diseasevery low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio

ANKRD31 ABCA1 PSD3 CPT1A LCP1 RGS12 FDFT1 PCSK6 FADS2

1.56e-062391349EFO_0008317, EFO_0020945
Diseasefree cholesterol:total lipids ratio, intermediate density lipoprotein measurement

ANKRD31 PSD3 CPT1A LCP1 PCSK6 FADS2

2.74e-06861346EFO_0008595, EFO_0020945
Diseasevery low density lipoprotein cholesterol measurement

ANKRD31 ABCA1 PSD3 TNFRSF10B LCP1 RGS12 FDFT1 NYNRIN FADS2

3.12e-062601349EFO_0008317
Diseasevery low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio

ANKRD31 ABCA1 PSD3 TNFRSF10B CPT1A LCP1 FDFT1 PCSK6 FADS2

3.53e-062641349EFO_0008317, EFO_0020944
Diseasechylomicron measurement, triglyceride measurement, very low density lipoprotein cholesterol measurement

PSD3 CPT1A LCP1 FDFT1 PCSK6 FADS2

5.20e-06961346EFO_0004530, EFO_0008317, EFO_0008596
Diseasecholesteryl esters:total lipids ratio, high density lipoprotein cholesterol measurement

ABCA1 PSD3 CPT1A LCP1 RGS12 FDFT1 PCSK6 FADS2

1.61e-052431348EFO_0004612, EFO_0020944
Diseaseautosomal recessive nonsyndromic deafness 114 (implicated_via_orthology)

GRB2 GRAP

2.05e-0521342DOID:0111642 (implicated_via_orthology)
Diseasetriacylglycerol 56:8 measurement

AHCTF1 CPT1A LCP1 FADS2

2.14e-05361344EFO_0010435
Diseasetriglyceride measurement, high density lipoprotein cholesterol measurement

ABCA1 PSD3 GRB2 LCP1 FDFT1 SIPA1L1 PCSK6 FADS2

3.79e-052741348EFO_0004530, EFO_0004612
Diseasecholesterol:total lipids ratio, high density lipoprotein cholesterol measurement

ABCA1 PSD3 CPT1A LCP1 RGS12 FDFT1 PCSK6 FADS2

3.99e-052761348EFO_0004612, EFO_0020943
Diseasetriglycerides:total lipids ratio, low density lipoprotein cholesterol measurement

ANKRD31 PSD3 CPT1A LCP1 PCSK6 FADS2

6.56e-051501346EFO_0004611, EFO_0020947
Diseaselow density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio

ANKRD31 ABCA1 PSD3 LCP1 FDFT1 FADS2

7.32e-051531346EFO_0004611, EFO_0020944
Diseasechylomicron measurement, very low density lipoprotein cholesterol measurement, lipid measurement

PSD3 CPT1A LCP1 FDFT1 FADS2

7.48e-05951345EFO_0004529, EFO_0008317, EFO_0008596
Diseasetriglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement

ANKRD31 ABCA1 PSD3 CPT1A LCP1 RGS12 PCSK6

7.89e-052251347EFO_0008317, EFO_0020947
Diseasepolyunsaturated fatty acids to total fatty acids percentage

PSD3 CPT1A LCP1 FADS2

7.96e-05501344EFO_0022303
Diseasecholesterol to total lipids in small HDL percentage

PSD3 LCP1 PCSK6 FADS2

8.61e-05511344EFO_0022240
Diseasecholesterol to total lipids in small VLDL percentage

ANKRD31 LCP1 PCSK6 FADS2

8.61e-05511344EFO_0022242
Diseasephospholipid measurement, high density lipoprotein cholesterol measurement

ABCA1 PSD3 LCP1 FDFT1 NYNRIN PCSK6 FADS2 MAPK4

1.14e-043211348EFO_0004612, EFO_0004639
Diseasetriglyceride measurement, low density lipoprotein cholesterol measurement

ABCA1 PSD3 LCP1 FDFT1 NYNRIN FADS2

1.15e-041661346EFO_0004530, EFO_0004611
Diseasechylomicron measurement, very low density lipoprotein cholesterol measurement

PSD3 CPT1A LCP1 FDFT1 FADS2

1.26e-041061345EFO_0008317, EFO_0008596
Diseasetriglycerides to total lipids in small VLDL percentage

ANKRD31 LCP1 PCSK6 FADS2

1.43e-04581344EFO_0022338
Diseasechylomicron measurement, very low density lipoprotein cholesterol measurement, phospholipid measurement

PSD3 CPT1A LCP1 FDFT1 FADS2

1.43e-041091345EFO_0004639, EFO_0008317, EFO_0008596
Diseasefree cholesterol measurement, chylomicron measurement, very low density lipoprotein cholesterol measurement

PSD3 CPT1A LCP1 FDFT1 FADS2

1.50e-041101345EFO_0008317, EFO_0008591, EFO_0008596
Diseasechylomicron measurement, total cholesterol measurement, very low density lipoprotein cholesterol measurement

PSD3 CPT1A LCP1 FDFT1 FADS2

1.50e-041101345EFO_0004574, EFO_0008317, EFO_0008596
Diseasetriglyceride measurement, intermediate density lipoprotein measurement

ABCA1 PSD3 LCP1 FDFT1 NYNRIN

1.56e-041111345EFO_0004530, EFO_0008595
Diseasefatty acid measurement

ANKRD31 ABCA1 PSD3 CPT1A LCP1 ESCO1 RGS12 FDFT1 FADS2

1.77e-044361349EFO_0005110
Diseasetriglycerides in medium LDL measurement

ABCA1 PSD3 LCP1 FADS2

1.85e-04621344EFO_0022322
Diseasetriglycerides to total lipids in medium VLDL percentage

ANKRD31 LCP1 RGS12 STIP1

1.97e-04631344EFO_0022335
Diseasecholesterol to total lipids in medium VLDL percentage

ANKRD31 LCP1 RGS12 STIP1

1.97e-04631344EFO_0022239
Diseasephosphatidylcholine (16:0/22:5n3, 18:1/20:4) measurement

CPT1A FADS2

2.03e-0451342EFO_0800467
Diseaseomega-3 polyunsaturated fatty acid measurement

ABCA1 CPT1A LCP1 FDFT1 FADS2

2.08e-041181345EFO_0010119
Diseasetriglycerides in small LDL measurement

ABCA1 PSD3 LCP1 FADS2

2.22e-04651344EFO_0022323
DiseaseColorectal Neoplasms

ABCA1 ABCA13 SCG5 CHD1 ABCG1 EGFR FADS2

2.84e-042771347C0009404
Diseaseesterified cholesterol measurement

ANKRD31 ABCA1 LCP1 NYNRIN FADS2

3.03e-041281345EFO_0008589
Diseasethioredoxin domain-containing protein 5 measurement

UTS2R TXNDC5

3.03e-0461342EFO_0802128
Diseasetriacylglycerol 56:7 measurement

AHCTF1 LCP1 FADS2

3.07e-04291343EFO_0010434
Diseaselow density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio

PSD3 CPT1A LCP1 FDFT1 PCSK6 FADS2

3.15e-042001346EFO_0004611, EFO_0020945
DiseaseColorectal Carcinoma

ABCA1 ABCA13 SCG5 CHD1 LIG1 MSH6 ABCG1 ARAP3 EGFR FADS2 MMP11

3.73e-0470213411C0009402
Diseasefree cholesterol to total lipids in small VLDL percentage

ANKRD31 PSD3 LCP1 FADS2

3.85e-04751344EFO_0022287
Diseasefree cholesterol measurement, low density lipoprotein cholesterol measurement

ABCA1 CPT1A LCP1 NYNRIN FADS2

4.14e-041371345EFO_0004611, EFO_0008591
Diseasesuberic acid measurement

VRK1 PSD3

4.24e-0471342EFO_0010534
DiseaseProfound Mental Retardation

VRK1 KDM5A TTI2 MED13L AP4E1

4.43e-041391345C0020796
DiseaseMental Retardation, Psychosocial

VRK1 KDM5A TTI2 MED13L AP4E1

4.43e-041391345C0025363
DiseaseMental deficiency

VRK1 KDM5A TTI2 MED13L AP4E1

4.43e-041391345C0917816
Diseasemonounsaturated fatty acids; 16:1, 18:1 measurement

PSD3 CPT1A LCP1 FADS2

4.47e-04781344EFO_0022187
Diseasetriglyceride measurement, physical activity

PSD3 ARL15 LCP1

4.94e-04341343EFO_0003940, EFO_0004530
Diseasecholesterol:total lipids ratio, low density lipoprotein cholesterol measurement

ANKRD31 ABCA1 CPT1A LCP1 FADS2

5.20e-041441345EFO_0004611, EFO_0020943
Diseasevery low density lipoprotein cholesterol measurement, lipid measurement

PSD3 TNFRSF10B LCP1 FDFT1 NYNRIN FADS2

5.21e-042201346EFO_0004529, EFO_0008317
Diseasefree cholesterol in small HDL measurement

ABCA1 LCP1 NYNRIN

5.39e-04351343EFO_0022270
Diseasevery low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio

ANKRD31 PSD3 CPT1A LCP1 RGS12 PCSK6

5.47e-042221346EFO_0008317, EFO_0020943
Diseasetriglyceride measurement, phospholipid measurement

PSD3 TNFRSF10B LCP1 FDFT1 FADS2

5.54e-041461345EFO_0004530, EFO_0004639
Diseasetriglyceride measurement, very low density lipoprotein cholesterol measurement

ABCA1 PSD3 TNFRSF10B LCP1 FDFT1 FADS2

5.73e-042241346EFO_0004530, EFO_0008317
Diseasediabetic nephropathy

VRK1 ITGA6 IGSF22 PCSK6 TTC21B

6.26e-041501345EFO_0000401
Diseasevery low density lipoprotein cholesterol measurement, phospholipid measurement

PSD3 TNFRSF10B LCP1 FDFT1 NYNRIN FADS2

6.43e-042291346EFO_0004639, EFO_0008317
Diseasenasopharyngeal neoplasm

MANEA LIG4 OSBPL1A ADGRE1 FOXC1

6.45e-041511345EFO_0004252
Diseaselow density lipoprotein cholesterol measurement, phospholipids:total lipids ratio

ABCA1 PSD3 LCP1 FDFT1 FADS2

6.85e-041531345EFO_0004611, EFO_0020946
DiseaseAbnormality of the face

FDFT1 TET3

7.22e-0491342C4025871
DiseaseArthritis, Collagen-Induced

TXNDC5 EGFR IL1RL1

8.00e-04401343C0971858
DiseaseArthritis, Experimental

TXNDC5 EGFR IL1RL1

8.00e-04401343C0993582
DiseaseArthritis, Adjuvant-Induced

TXNDC5 EGFR IL1RL1

8.00e-04401343C0003865
Diseaseaspartate aminotransferase to alanine aminotransferase ratio

ANKRD31 RGS12 ZNF250 ST8SIA6 NYNRIN UHRF1

8.03e-042391346EFO_0010934
DiseaseHuman papillomavirus infectious disease (is_marker_for)

EGFR IL1RL1

8.99e-04101342DOID:11166 (is_marker_for)
Diseasesystolic blood pressure, self reported educational attainment

THSD7A CDON

8.99e-04101342EFO_0004784, EFO_0006335
Diseaseoleoyl-linoleoyl-glycerol (18:1/18:2) [2] measurement

LCP1 FADS2

8.99e-04101342EFO_0800333
DiseaseAdenocarcinoma of large intestine

MSH6 EGFR PAK3 PRKDC

9.78e-04961344C1319315
Diseasetriacylglycerol 56:6 measurement

AHCTF1 LCP1 FADS2

9.90e-04431343EFO_0010433
Diseasefree cholesterol to total lipids in IDL percentage

LCP1 PCSK6 FADS2

9.90e-04431343EFO_0022278
Diseasecoronary artery calcification

ABCA1 PSD3 OLA1 MED13L CPT1A LCP1 SIPA1L1 FBXO15

1.08e-034501348EFO_0004723
Diseasephosphatidylcholine 32:0 measurement

MAN1A1 FADS2

1.10e-03111342EFO_0010372
Diseaselevel of Sterol ester (27:1/20:5) in blood serum

CPT1A FADS2

1.10e-03111342OBA_2045197
Diseaseoleoyl-linoleoyl-glycerol (18:1/18:2) [1] measurement

LCP1 FADS2

1.10e-03111342EFO_0800332
Diseaselow density lipoprotein cholesterol measurement, alcohol consumption measurement

ABCA1 PSD3 NYNRIN FADS2

1.10e-03991344EFO_0004611, EFO_0007878
Diseasetriglyceride measurement, alcohol drinking

ABCA1 PSD3 LCP1 FADS2

1.10e-03991344EFO_0004329, EFO_0004530
Diseasesaturated fatty acids measurement

ABCA1 PSD3 LCP1

1.13e-03451343EFO_0022304
Diseasecholesteryl ester measurement

ANKRD31 ABCA1 PSD3 LCP1 NYNRIN FADS2

1.17e-032571346EFO_0010351
Diseasetriglyceride measurement, alcohol consumption measurement

ABCA1 PSD3 LCP1 FADS2

1.18e-031011344EFO_0004530, EFO_0007878
Diseasetriacylglycerol 54:4 measurement

ITGA6 LCP1 FADS2

1.21e-03461343EFO_0010422
Diseaselow density lipoprotein cholesterol measurement, alcohol drinking

ABCA1 PSD3 NYNRIN FADS2

1.23e-031021344EFO_0004329, EFO_0004611
DiseaseMalignant neoplasm of breast

UTS2R MANEA OLA1 CPT1A MSH6 ARAP3 EGFR SIPA1L1 POP1 SERPINB2 MAP7D2 UQCC1 NOS2

1.24e-03107413413C0006142
DiseasePathological accumulation of air in tissues

PPP2R2C NOS2

1.31e-03121342C0013990
Diseaseautosomal dominant cerebellar ataxia (implicated_via_orthology)

PPP2R2B PPP2R2C

1.31e-03121342DOID:1441 (implicated_via_orthology)
Diseasearachidonoylcarnitine (C20:4) measurement

CPT1A FADS2

1.31e-03121342EFO_0800544
DiseaseKidney Failure, Chronic

ABCA1 CPT1A ABCG1

1.36e-03481343C0022661
Diseasecholesteryl esters to total lipids in small VLDL percentage

ANKRD31 LCP1 PCSK6

1.45e-03491343EFO_0022256
Diseasedihomo-linolenoylcarnitine (C20:3n3 or 6) measurement

CPT1A FADS2

1.55e-03131342EFO_0800547
Diseasecholesteryl ester measurement, chylomicron measurement, very low density lipoprotein cholesterol measurement

PSD3 LCP1 FDFT1 FADS2

1.62e-031101344EFO_0008317, EFO_0008596, EFO_0010351
Diseasefree cholesterol in large LDL measurement

ANKRD31 ABCA1 LCP1

1.63e-03511343EFO_0022176
Diseasetotal cholesterol measurement, diastolic blood pressure, triglyceride measurement, systolic blood pressure, hematocrit, ventricular rate measurement, glucose measurement, body mass index, high density lipoprotein cholesterol measurement

ANKRD31 LCP1 FADS2

1.63e-03511343EFO_0004340, EFO_0004348, EFO_0004468, EFO_0004530, EFO_0004574, EFO_0004612, EFO_0006335, EFO_0006336, EFO_0007928
Diseasepolyunsaturated fatty acids to monounsaturated fatty acids ratio

PSD3 CPT1A LCP1

1.63e-03511343EFO_0022302
Diseasefree cholesterol to total lipids in small HDL percentage

ABCA1 CPT1A FADS2

1.63e-03511343EFO_0022285
Diseaselinoleic acid measurement

ABCA1 THSD7B LCP1 FDFT1 FADS2

1.63e-031861345EFO_0006807
DiseaseSaldino-Noonan Syndrome

C2CD3 TTC21B

1.80e-03141342C0036069
DiseaseAsbestosis

NLRP3 NOS2

1.80e-03141342C0003949
DiseasePulmonary Fibrosis - from Asbestos Exposure

NLRP3 NOS2

1.80e-03141342C2930617
Diseasetriglycerides to total lipids in very large VLDL percentage

ANKRD31 CPT1A LCP1

1.82e-03531343EFO_0022340
Diseasetriglycerides in HDL measurement

ABCA1 LCP1 FADS2

1.82e-03531343EFO_0022317
Diseasefree cholesterol to total lipids in small LDL percentage

PSD3 LCP1 FADS2

1.82e-03531343EFO_0022286
Diseaseantihyperlipidemic drug use measurement

ABCA1 PSD3 LCP1 FADS2

1.90e-031151344EFO_0803367
DiseasePeripheral Nervous System Diseases

ABCA1 MYO5A SERPINB2

1.92e-03541343C4721453
Diseasealcohol use disorder (implicated_via_orthology)

KDM5A PSD3 EGFR FADS2 CTSV

2.01e-031951345DOID:1574 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
VLKAWLDITRGKEPY

TTC21B

146

Q7Z4L5
KLWKVSERDKRPEGY

PPP2R2B

116

Q00005
KLWKITERDKRPEGY

PPP2R2C

116

Q9Y2T4
YKPTKGWEERTKKIG

CCDC112

406

Q8NEF3
WPLEGAKVYLGIRKK

ARAP3

1271

Q8WWN8
KKYFELEPLARGKRW

ARL15

156

Q9NXU5
SSPRKWYSPIKGKLD

ANTXR1

441

Q9H6X2
KGKLDALWVLLRKGY

ANTXR1

451

Q9H6X2
LPYKTGKKGDVWRLG

EIF2AK4

471

Q9P2K8
VPEGPWWRKKGYKTL

ABCG1

86

P45844
REQYGKWSKGIRKLK

ADGRE2

786

Q9UHX3
FLDLPKSVDWRKKGY

CTSV

111

O60911
KSVDWREKGYVTPVK

CTSL3P

61

Q5NE16
RYGVWYLKPKLGKKL

FAM47DP

311

A6NHR8
WYKAELRGVEGFIPK

GRAPL

36

Q8TC17
WYKAELRGVEGFIPK

GRAP

36

Q13588
EWAIRKLGLVKYGEK

ABCA1

2026

O95477
VGGQEKLRPLWKSYT

ARL4A

76

P40617
VGLGPRLQWYLKLKS

CPT1A

211

P50416
ELWAYGISKGKRAKL

ABCA13

836

Q86UQ4
DYPGLGKWNKKLLYE

SCG5

156

P05408
KGKGKVRTYWLLGER

NPR1

1041

P16066
IKWPKSVEVEGYGSK

DHX30

91

Q7L2E3
LVRKKKKIPGYRWGD

CBLL2

26

Q8N7E2
KKIPGYRWGDIKINI

CBLL2

31

Q8N7E2
KEPGEIQYLIKWKGW

CHD1

311

O14646
LKLEGIKKLWGKEGY

AP4E1

701

Q9UPM8
KIGYELWIKKRVGDG

QRFPR

236

Q96P65
KIKEWVDKYDPGALV

OLA1

246

Q9NTK5
LEQKIKGWYEKCEPG

KRT26

111

Q7Z3Y9
IYKNPVTWLKDLLGG

ANKRD31

1741

Q8N7Z5
IDLGWKPKYGRFDVV

NOS2

291

P35228
LGEWQPIEYGKKKLK

FADS2

241

O95864
KYLIARGKLDWAEGP

FHIP1B

826

Q8N612
RKAYGPKVDIWSLGI

PAK3

451

O75914
LEVIPKIWKDSKEYG

PTCD3

506

Q96EY7
LKLWLEKFVYKGGLT

LRTM1

191

Q9HBL6
EIYKKGQSKRIWGEL

GNL2

196

Q13823
RIGKWFVRPYEKDEK

MED13L

141

Q71F56
SLPWVGKELYEKKDA

NCBP1

176

Q09161
KPLLYEIGWGKKLSY

NGLY1

361

Q96IV0
GKYKPGRCDDILKWK

RNGTT

446

O60942
LELKKKYSWGAPLAI

MAP7D2

141

Q96T17
YRLLVTKKEEGPWKS

MTIF2

66

P46199
REELEKWLKKEPGAY

INMT

91

O95050
KVGSPSYLDKLLWRD

MAPK4

431

P31152
KLRTLGYDESKLAPW

ESPN

826

B1AK53
WSRYVKKLGDFAKPE

FDFT1

236

P37268
DKEKIREKYGPEWAR

C1orf198

46

Q9H425
KLWKKYGSRFPQDDL

HNMT

181

P50135
PEKQGKLKEWSLILY

PCSK6

616

P29122
LKEGKPYLVLGLLWQ

LCP1

216

P13796
GPKGVINDWRKFKLE

PDC

21

P20941
LKLVEYKGQKWVDGG

PNPLA4

151

P41247
WYFEPKLGKKLRSDE

FAM47B

551

Q8NA70
DLEQKIKGWYEKFGP

KRT27

111

Q7Z3Y8
DLEQKIKGWYEKFGP

KRT25

106

Q7Z3Z0
GKWLLYLVKVESKGL

ITGA6

901

P23229
GWVSKRLLKPYTGSK

MSH6

141

P52701
GSIYPKLKFWGKSVE

OSBPL1A

671

Q9BXW6
WYKAELNGKDGFIPK

GRB2

36

P62993
PLWGKLRVDIKAYLG

NOC2L

241

Q9Y3T9
EKKWSKVGSRLGYLP

KDM5A

136

P29375
KPGLYLELTRKWSEK

MANEA

431

Q5SRI9
KKWGYCLGERPTVKS

POP1

216

Q99575
YKGSFPKWTRKGLEE

CDK3

236

Q00526
VYKGLWIPEGEKVKI

EGFR

726

P00533
DKPLIYKGEGKWLRN

ATRX

2066

P46100
WRDIAKPYKTRNDGK

IL1RL1

361

Q01638
FRGKPLPKVTWYKDG

IGSF22

631

Q8N9C0
KELLIKRSGITGWYP

C2CD3

1326

Q4AC94
AGEGVQRKKPLYWDL

DOK1

326

Q99704
SIYKPDKRGEGWLKI

LIG4

436

P49917
DKRGEGWLKIKPEYV

LIG4

441

P49917
KVFDGWILKGEKFPS

CRHBP

111

P24387
PWDGGLKRAKVKDIF

GPAT3

401

Q53EU6
KYTDPFKLGWRDLKG

PDSS1

91

Q5T2R2
LGWAIILKEKGGKEY

FBXO15

196

Q8NCQ5
RDDKKPGKGSYWTLD

FOXC1

141

Q12948
LLDKKEYRKPIDWGA

CRYGS

151

P22914
LYSGWLRKSPPEKKL

GAB4

41

Q2WGN9
SNPKAEVRYKIRGKW

CDON

146

Q4KMG0
SRWYGKRKVEGLPYK

CFAP107

66

Q8N1D5
ARKKYGPKIDVWSIG

HUNK

236

P57058
RIAPKTVWDYVGKLK

DIDO1

1096

Q9BTC0
KGYAWGLNELKPISK

MAN1A1

211

P33908
VWFKRPDGSKSKLYI

BRMS1L

296

Q5PSV4
VGWKKERILAEYPDG

ESCO1

651

Q5FWF5
IEKLWKRDEGGTGKY

AHCTF1

736

Q8WYP5
PEKLKLEWAYGYRGK

EML4

256

Q9HC35
KKTWKPFIGYDSLRI

DDHD1

176

Q8NEL9
MKVLRGIWVAYEKPG

CRYBG1

1266

Q9Y4K1
WSLKSDGRIYSKLKP

CRYBG1

1671

Q9Y4K1
NWLKLKKDYLDGVGD

LIG1

741

P18858
GYKELRKPLEKEGWK

CTNND1

831

O60716
LPEFKKKAVWTRAYG

FOCAD

1786

Q5VW36
KEYLKGLCSPELWKE

NYNRIN

66

Q9P2P1
GKWKTPFEKKLNGLY

SERPINB2

206

P05120
RDLYEKAKRDEPKWG

NLRP3

81

Q96P20
RGRLYWKFDPVKVKA

MMP11

451

P24347
KETGRETKYPWKEFL

TAF3

566

Q5VWG9
DLKPDWGKGYSRKAA

STIP1

66

P31948
KKAYLEWPKDRRKCG

TLR10

751

Q9BXR5
KVRSKWLREKPYNGG

THSD7A

1056

Q9UPZ6
RGGKYIWSKADLKLD

RSAD2

346

Q8WXG1
VKIWRQEGPLALYKG

SLC25A34

256

Q6PIV7
KRKLLGWKEPGEAFV

NHSL2

1121

Q5HYW2
WVDKYKPTSLKTIIG

RFC1

586

P35251
SSKYKWILGEEPVEK

MORC4

561

Q8TE76
RQGATSKYLIGWKKP

SIPA1L1

1476

O43166
SKYLIGWKKPEGTIN

SIPA1L1

1481

O43166
PKYLKDLALFWRTKG

ST8SIA6

301

P61647
RWSKDGKELRDGPKY

SPEGNB

86

A0A087WV53
YKTGHGLRGKLKWRP

RO60

331

P10155
VREEYKRWITGKTKP

ADGRE1

851

Q14246
LDYWAQKEKEGKRGP

ACSM1

56

Q08AH1
KKVGYTPDWIFLLRG

CLTCL1

506

P53675
RGEDPWVLDRKGAKK

ZNF250

76

P15622
YEGGVWKVRVDLPDK

UBE2H

46

P62256
GGLYEGKGWLKPKLD

RGS12

111

O14924
ILGLLKPDLYKESWK

TTI2

206

Q6NXR4
PKKGIWLEAGKALDY

TLN1

56

Q9Y490
KKPGVYTRITRLKGW

TMPRSS9

716

Q7Z410
TPVKELVSLKWKRYG

TRPV6

351

Q9H1D0
LWPEKAALKVLGKDY

nan

196

A8MX80
TPAYITKKRGEWKDL

SENP8

191

Q96LD8
LWKKVLPYLKGICSG

TNFRSF10B

236

O14763
GFTGPLKYSKWKIKI

UQCC1

101

Q9NVA1
EAKLYGKKRKWGGTV

TET3

1736

O43151
EEWALLGPSQKKLYR

ZNF709

16

Q8N972
RTRKLKYLGVPKYWG

VRK1

101

Q99986
SGEVRTGKWKVPTYK

PRKDC

511

P78527
VVKYWPEKGKSGFLV

UHRF1

561

Q96T88
PEKGKSGFLVWRYLL

UHRF1

566

Q96T88
RPKGYRKLLALGTWL

UTS2R

161

Q9UKP6
GKEPWKVVRKGRRQY

ZFP82

61

Q8N141
GYPTLLWFRDGKKVD

TXNDC5

261

Q8NBS9
IEAKGKKVRGRLYPW

SEPTIN2

246

Q15019
GSYLWLQLEGSKKPI

SFMBT1

411

Q9UHJ3
RIRSKWLKEKPYNGG

THSD7B

1021

Q9C0I4
KLIWGPYKMDSKGDV

SEC31A

71

O94979
PRGKRGWKTFYAVLK

PSD3

806

Q9NYI0
KVLWRYKGKKPATLG

UGT2A2

341

P0DTE5
VWKSAELLKDYKPGD

MYO5A

21

Q9Y4I1
KWRSYKGELFDKTPV

MYORG

681

Q6NSJ0
AGWEEEKKKGYDLRP

NEB

1786

P20929