Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncalcium ion binding

MATN3 PCDHAC1 CUBN CRB1 LRP8 SNED1 SLIT2 NELL1 THBD FBLN1 NELL2 EYS SCUBE1 HEG1 FBN2 PROZ HMCN1 MEGF8 LRP1 SCUBE3 LRP2 LTBP4 NOTCH1 NOTCH2 NOTCH3 NOTCH4

8.28e-1474911426GO:0005509
GeneOntologyMolecularFunctionextracellular matrix structural constituent

FRAS1 VWF MATN3 LAMA1 LAMA5 LAMB1 SSPOP SLIT2 FBLN1 FBN2 PXDN HMCN1 LTBP4 MUC5AC MUC6

2.13e-1318811415GO:0005201
GeneOntologyMolecularFunctionubiquitin protein ligase activity

BIRC8 RNF168 TRIM61 TRIM31 XIAP SIAH1 TRIM21 RNF114 TRIM10 HECTD2 CHFR NFX1 RNF208 NSMCE1 TRIM60

3.34e-0937211415GO:0061630
GeneOntologyMolecularFunctionubiquitin-like protein ligase activity

BIRC8 RNF168 TRIM61 TRIM31 XIAP SIAH1 TRIM21 RNF114 TRIM10 HECTD2 CHFR NFX1 RNF208 NSMCE1 TRIM60

8.30e-0939811415GO:0061659
GeneOntologyMolecularFunctionubiquitin-protein transferase activity

BIRC8 RNF168 TRIM61 TRIM31 XIAP SIAH1 TRIM21 RNF114 TRIM10 HECTD2 CHFR NFX1 HERC1 RNF208 NSMCE1 TRIM60

1.17e-0847311416GO:0004842
GeneOntologyMolecularFunctionubiquitin-like protein transferase activity

BIRC8 RNF168 TRIM61 TRIM31 XIAP SIAH1 TRIM21 RNF114 TRIM10 HECTD2 CHFR NFX1 HERC1 RNF208 NSMCE1 TRIM60

3.53e-0851211416GO:0019787
GeneOntologyMolecularFunctionaminoacyltransferase activity

BIRC8 RNF168 TRIM61 TRIM31 XIAP SIAH1 TRIM21 RNF114 TRIM10 HECTD2 CHFR NFX1 HERC1 RNF208 NSMCE1 TRIM60

5.98e-0853211416GO:0016755
GeneOntologyMolecularFunctionNotch binding

SNED1 NOTCH1 MEGF10 NOTCH4 CCN3

4.05e-07271145GO:0005112
GeneOntologyMolecularFunctionacyltransferase activity

BIRC8 RNF168 TRIM61 TRIM31 ZDHHC14 XIAP SIAH1 TRIM21 RNF114 TRIM10 HECTD2 CHFR NFX1 HERC1 RNF208 NSMCE1 TRIM60

1.89e-0677511417GO:0016746
GeneOntologyMolecularFunctionintegrin binding

VWF LAMA5 LAMB1 ITGA9 FBLN1 TIMP2 LTBP4 CCN3

7.41e-061751148GO:0005178
GeneOntologyMolecularFunctiontransmembrane receptor protein kinase activity

ERBB3 CRIM1 INSRR ACVR1C MET LTBP4

9.19e-06851146GO:0019199
GeneOntologyMolecularFunctionstructural molecule activity

FRAS1 VWF MATN3 LAMA1 LAMA5 LAMB1 LAMC3 SSPOP SLIT2 FBLN1 FBN2 PXDN HMCN1 LTBP4 MUC5AC MUC6 OTOG

1.20e-0589111417GO:0005198
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor activity

LRP8 LRP1 LRP2

9.61e-05161143GO:0005041
GeneOntologyMolecularFunctioncargo receptor activity

CUBN LRP8 LRP1 LRP2 MEGF10

1.27e-04851145GO:0038024
GeneOntologyMolecularFunctionlinoleic acid epoxygenase activity

CYP2C9 CYP2C18

1.92e-0441142GO:0071614
GeneOntologyMolecularFunctionapolipoprotein binding

LRP8 LRP1 PCSK9

1.92e-04201143GO:0034185
GeneOntologyMolecularFunctionlipoprotein particle receptor activity

LRP8 LRP1 LRP2

2.24e-04211143GO:0030228
GeneOntologyMolecularFunctionhistone H3K9 trimethyltransferase activity

SETDB1 PRDM9

3.19e-0451142GO:0140949
GeneOntologyMolecularFunctiontransmembrane receptor protein tyrosine kinase activity

ERBB3 CRIM1 INSRR MET

5.22e-04651144GO:0004714
GeneOntologyMolecularFunctionprotease binding

BIRC8 VWF XIAP TIMP2 LRP1 TNFRSF1A

6.06e-041811146GO:0002020
GeneOntologyMolecularFunctionlaminin-1 binding

SLIT2 PXDN

8.85e-0481142GO:0043237
GeneOntologyMolecularFunctionlaminin binding

ITGA9 SLIT2 PXDN

9.53e-04341143GO:0043236
GeneOntologyMolecularFunctionhistone H4K20 methyltransferase activity

SMYD5 PRDM9

1.41e-03101142GO:0042799
GeneOntologyMolecularFunctionlipoprotein particle receptor binding

LRP1 LRP2 PCSK9

1.43e-03391143GO:0070325
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

TSPAN12 ERBB3 CRIM1 OR4C16 INSRR RXFP3 ACVR1C LRP8 MET THBD PKD1 PTCH2 RXFP4 TNFRSF1A LTBP4 NOTCH1 NOTCH2

1.71e-03135311417GO:0004888
GeneOntologyMolecularFunctionhemoglobin binding

CUBN LRP2

1.72e-03111142GO:0030492
GeneOntologyMolecularFunctiongrowth factor binding

ERBB3 ACVR1C PXDN LRP2 LTBP4

2.02e-031561145GO:0019838
GeneOntologyMolecularFunctionactivin binding

FSTL3 ACVR1C

2.05e-03121142GO:0048185
GeneOntologyMolecularFunctioncell adhesion molecule binding

VWF LAMA5 LAMB1 ITGA9 FBLN1 TENM4 TIMP2 LTBP4 NOTCH3 CCN3

2.28e-0359911410GO:0050839
GeneOntologyMolecularFunctionhistone H3K9 methyltransferase activity

SETDB1 PRDM9

2.42e-03131142GO:0046974
GeneOntologyMolecularFunctionglycosphingolipid binding

LAMA1 LAMB1

2.42e-03131142GO:0043208
GeneOntologyMolecularFunctionBMP receptor binding

ACVR1C SCUBE3

2.42e-03131142GO:0070700
GeneOntologyMolecularFunctionretinoic acid 4-hydroxylase activity

CYP2C9 CYP2C18

2.81e-03141142GO:0008401
GeneOntologyMolecularFunctionpeptidase regulator activity

BIRC8 CRIM1 XIAP SSPOP FBLN1 TIMP2

3.59e-032571146GO:0061134
GeneOntologyMolecularFunctionWnt receptor activity

TSPAN12 PKD1

4.15e-03171142GO:0042813
GeneOntologyMolecularFunctionhistone H4 methyltransferase activity

SMYD5 PRDM9

4.15e-03171142GO:0140939
GeneOntologyMolecularFunctionglycosaminoglycan binding

CRISPLD2 SLIT2 NELL1 NELL2 LTBP4 CCN3

4.41e-032681146GO:0005539
GeneOntologyMolecularFunctionzinc ion binding

TRIM61 DBF4B TRPS1 TRIM31 SIAH1 TRIM21 TRIM10 SETDB1 PRDM9 TIMP2 NFX1 TRIM60

4.92e-0389111412GO:0008270
GeneOntologyMolecularFunctionheparin binding

CRISPLD2 SLIT2 NELL1 NELL2 CCN3

4.92e-031921145GO:0008201
GeneOntologyMolecularFunctiontransmembrane receptor protein serine/threonine kinase activity

ACVR1C LTBP4

5.74e-03201142GO:0004675
GeneOntologyBiologicalProcessaxon guidance

LAMA1 LAMA5 LAMB1 SIAH1 LAMC3 SLIT2 NELL2 MEGF8 LRP1 LRP2 ULK2 NOTCH1 NOTCH2 NOTCH3

6.87e-1028511514GO:0007411
GeneOntologyBiologicalProcessneuron projection guidance

LAMA1 LAMA5 LAMB1 SIAH1 LAMC3 SLIT2 NELL2 MEGF8 LRP1 LRP2 ULK2 NOTCH1 NOTCH2 NOTCH3

7.19e-1028611514GO:0097485
GeneOntologyBiologicalProcessneuron projection morphogenesis

SPRY3 LAMA1 LAMA5 LAMB1 SIAH1 LAMC3 SLITRK3 LRP8 SLIT2 MET NELL2 MEGF8 LRP1 LRP2 ULK2 NOTCH1 NOTCH2 NOTCH3

4.69e-0780211518GO:0048812
GeneOntologyBiologicalProcesscell surface receptor protein serine/threonine kinase signaling pathway

FSTL3 CRIM1 TRPS1 XIAP ACVR1C FBN2 MEGF8 LRP1 SCUBE3 LRP2 LTBP4 NOTCH1 NOTCH2 CCN3

4.95e-0748211514GO:0007178
GeneOntologyBiologicalProcessaxon development

LAMA1 LAMA5 LAMB1 SIAH1 LAMC3 GRN SLITRK3 SLIT2 NELL2 MEGF8 LRP1 LRP2 ULK2 NOTCH1 NOTCH2 NOTCH3

5.54e-0764211516GO:0061564
GeneOntologyBiologicalProcessaxonogenesis

LAMA1 LAMA5 LAMB1 SIAH1 LAMC3 SLITRK3 SLIT2 NELL2 MEGF8 LRP1 LRP2 ULK2 NOTCH1 NOTCH2 NOTCH3

6.00e-0756611515GO:0007409
GeneOntologyBiologicalProcessplasma membrane bounded cell projection morphogenesis

SPRY3 LAMA1 LAMA5 LAMB1 SIAH1 LAMC3 SLITRK3 LRP8 SLIT2 MET NELL2 MEGF8 LRP1 LRP2 ULK2 NOTCH1 NOTCH2 NOTCH3

6.35e-0781911518GO:0120039
GeneOntologyBiologicalProcesscell projection morphogenesis

SPRY3 LAMA1 LAMA5 LAMB1 SIAH1 LAMC3 SLITRK3 LRP8 SLIT2 MET NELL2 MEGF8 LRP1 LRP2 ULK2 NOTCH1 NOTCH2 NOTCH3

7.18e-0782611518GO:0048858
GeneOntologyBiologicalProcesscell morphogenesis involved in neuron differentiation

LAMA1 LAMA5 LAMB1 SIAH1 LAMC3 SLITRK3 LRP8 SLIT2 MET NELL2 MEGF8 LRP1 LRP2 ULK2 NOTCH1 NOTCH2 NOTCH3

8.52e-0774811517GO:0048667
GeneOntologyBiologicalProcessneuron development

SPRY3 LAMA1 LAMA5 LAMB1 SIAH1 LAMC3 GRN SLITRK3 CRB1 LRP8 SLIT2 MET DZANK1 NELL2 TENM4 MEGF8 LRP1 LRP2 HERC1 ULK2 NOTCH1 NOTCH2 NOTCH3 OTOG

1.43e-06146311524GO:0048666
GeneOntologyBiologicalProcesscell morphogenesis

SPRY3 LAMA1 LAMA5 LAMB1 SIAH1 LAMC3 SLITRK3 CRB1 LRP8 SLIT2 MET NELL2 HEG1 MEGF8 LRP1 LRP2 ULK2 NOTCH1 NOTCH2 NOTCH3 NOTCH4

2.47e-06119411521GO:0000902
GeneOntologyBiologicalProcessregulation of cellular response to growth factor stimulus

SPRY3 FSTL3 CRIM1 XIAP SLIT2 FBN2 LRP1 SCUBE3 LRP2 LTBP4 NOTCH1 NOTCH2

3.32e-0641211512GO:0090287
GeneOntologyBiologicalProcessregulation of transmembrane receptor protein serine/threonine kinase signaling pathway

FSTL3 CRIM1 XIAP FBN2 LRP1 SCUBE3 LRP2 LTBP4 NOTCH1 NOTCH2 CCN3

3.90e-0634711511GO:0090092
GeneOntologyBiologicalProcessgliogenesis

ERBB3 LAMB1 GSX2 LAMC3 GRN CRB1 LRP8 TENM4 LRP1 LRP2 NOTCH1 NOTCH2

5.78e-0643511512GO:0042063
GeneOntologyBiologicalProcessanimal organ morphogenesis

TSPAN12 FRAS1 LAMA1 LAMA5 LAMB1 GSX2 LAMC3 CRB1 SLIT2 MET DZANK1 HEG1 FBN2 MEGF8 PKD1 LRP2 OTOP1 FHL2 USH2A NOTCH1 NOTCH2

6.38e-06126911521GO:0009887
GeneOntologyBiologicalProcesstransforming growth factor beta receptor superfamily signaling pathway

FSTL3 CRIM1 XIAP ACVR1C FBN2 MEGF8 LRP1 SCUBE3 LRP2 LTBP4 NOTCH1 NOTCH2

7.27e-0644511512GO:0141091
GeneOntologyBiologicalProcessneuron projection development

SPRY3 LAMA1 LAMA5 LAMB1 SIAH1 LAMC3 GRN SLITRK3 LRP8 SLIT2 MET NELL2 MEGF8 LRP1 LRP2 HERC1 ULK2 NOTCH1 NOTCH2 NOTCH3 OTOG

7.73e-06128511521GO:0031175
GeneOntologyBiologicalProcessextracellular matrix organization

CRISPLD2 MATN3 LAMA1 LAMB1 FBLN1 PXDN HMCN1 LRP1 TNFRSF1A LTBP4 NOTCH1

8.56e-0637711511GO:0030198
GeneOntologyBiologicalProcessextracellular structure organization

CRISPLD2 MATN3 LAMA1 LAMB1 FBLN1 PXDN HMCN1 LRP1 TNFRSF1A LTBP4 NOTCH1

8.78e-0637811511GO:0043062
GeneOntologyBiologicalProcessregulation of BMP signaling pathway

FSTL3 CRIM1 XIAP SCUBE3 LRP2 NOTCH1 NOTCH2

8.80e-061311157GO:0030510
GeneOntologyBiologicalProcesspulmonary valve development

SLIT2 TNFRSF1A NOTCH1 NOTCH2

8.94e-06241154GO:0003177
GeneOntologyBiologicalProcessexternal encapsulating structure organization

CRISPLD2 MATN3 LAMA1 LAMB1 FBLN1 PXDN HMCN1 LRP1 TNFRSF1A LTBP4 NOTCH1

9.00e-0637911511GO:0045229
GeneOntologyBiologicalProcessprotein modification by small protein conjugation

BIRC8 RNF168 TRIM61 TRIM31 XIAP SIAH1 TRIM21 RNF114 TRIM10 MEGF8 HECTD2 CHFR NFX1 HERC1 RNF208 NSMCE1 TRIM60

9.15e-0689311517GO:0032446
GeneOntologyBiologicalProcessprotein ubiquitination

BIRC8 RNF168 TRIM61 TRIM31 XIAP SIAH1 TRIM21 RNF114 TRIM10 MEGF8 HECTD2 CHFR NFX1 HERC1 RNF208 TRIM60

1.11e-0581111516GO:0016567
GeneOntologyBiologicalProcessartery morphogenesis

MEGF8 LRP1 LRP2 NOTCH1 NOTCH3 NOTCH4

1.27e-05921156GO:0048844
GeneOntologyBiologicalProcessBMP signaling pathway

FSTL3 CRIM1 XIAP MEGF8 SCUBE3 LRP2 NOTCH1 NOTCH2

1.48e-051971158GO:0030509
GeneOntologyBiologicalProcesspositive regulation of cell differentiation

LAMA1 LAMB1 GSX2 LRP8 SLIT2 MET NELL1 FBN2 TENM4 MEGF8 TIMP2 LRP1 PTCH2 SCUBE3 LRP2 NOTCH1 NOTCH2 NOTCH4 CCN3

1.72e-05114111519GO:0045597
GeneOntologyBiologicalProcesspositive regulation of nervous system development

GSX2 SLITRK3 LRP8 SLIT2 MET TENM4 MEGF8 LRP1 LRP2 NOTCH1 NOTCH2

2.24e-0541811511GO:0051962
GeneOntologyBiologicalProcessresponse to BMP

FSTL3 CRIM1 XIAP MEGF8 SCUBE3 LRP2 NOTCH1 NOTCH2

2.78e-052151158GO:0071772
GeneOntologyBiologicalProcesscellular response to BMP stimulus

FSTL3 CRIM1 XIAP MEGF8 SCUBE3 LRP2 NOTCH1 NOTCH2

2.78e-052151158GO:0071773
GeneOntologyBiologicalProcessenzyme-linked receptor protein signaling pathway

SPRY3 ERBB3 FSTL3 CRIM1 TRPS1 INSRR XIAP ACVR1C MET FBN2 MEGF8 FAM72A LRP1 SCUBE3 LRP2 LTBP4 NOTCH1 NOTCH2 CCN3

2.93e-05118611519GO:0007167
GeneOntologyBiologicalProcesspositive regulation of neurogenesis

GSX2 LRP8 SLIT2 MET TENM4 MEGF8 LRP1 LRP2 NOTCH1 NOTCH2

2.95e-0535411510GO:0050769
GeneOntologyBiologicalProcessendocytic hemoglobin import into cell

CUBN LRP2

3.08e-0521152GO:0020028
GeneOntologyBiologicalProcessnegative regulation of small GTPase mediated signal transduction

SPRY3 SLIT2 MET HEG1 TIMP2

3.62e-05671155GO:0051058
GeneOntologyBiologicalProcesscirculatory system development

TSPAN12 ERBB3 LAMA1 GRN SLIT2 MET SCUBE1 HEG1 TENM4 PXDN MEGF8 PKD1 LRP1 LRP2 TNFRSF1A FHL2 NOTCH1 NOTCH2 NOTCH3 NOTCH4 CCN3

4.32e-05144211521GO:0072359
GeneOntologyBiologicalProcessprotein modification by small protein conjugation or removal

BIRC8 RNF168 TRIM61 TRIM31 XIAP SIAH1 TRIM21 RNF114 TRIM10 MEGF8 HECTD2 CHFR NFX1 HERC1 RNF208 NSMCE1 TRIM60

4.35e-05100911517GO:0070647
GeneOntologyBiologicalProcessvenous blood vessel morphogenesis

HEG1 NOTCH1 NOTCH4

4.64e-05131153GO:0048845
GeneOntologyBiologicalProcessblood vessel morphogenesis

TSPAN12 LAMA1 GRN SLIT2 HEG1 PXDN MEGF8 LRP1 LRP2 TNFRSF1A NOTCH1 NOTCH2 NOTCH3 NOTCH4 CCN3

4.89e-0581711515GO:0048514
GeneOntologyBiologicalProcesstube morphogenesis

TSPAN12 LAMA1 LAMA5 GRN SLIT2 MET HEG1 PXDN MEGF8 PKD1 LRP1 LRP2 TNFRSF1A NOTCH1 NOTCH2 NOTCH3 NOTCH4 CCN3

4.96e-05112511518GO:0035239
GeneOntologyBiologicalProcessblood vessel development

TSPAN12 LAMA1 GRN SLIT2 HEG1 PXDN MEGF8 PKD1 LRP1 LRP2 TNFRSF1A NOTCH1 NOTCH2 NOTCH3 NOTCH4 CCN3

5.76e-0592911516GO:0001568
GeneOntologyBiologicalProcessendothelial cell morphogenesis

MET HEG1 NOTCH4

7.32e-05151153GO:0001886
GeneOntologyBiologicalProcesscellular response to growth factor stimulus

SPRY3 FSTL3 CRIM1 XIAP ACVR1C LRP8 SLIT2 FBN2 MEGF8 LRP1 SCUBE3 LRP2 LTBP4 NOTCH1 NOTCH2

7.63e-0585011515GO:0071363
GeneOntologyBiologicalProcessglial cell differentiation

ERBB3 GSX2 LAMC3 GRN CRB1 TENM4 LRP1 NOTCH1 NOTCH2

7.94e-053211159GO:0010001
GeneOntologyBiologicalProcessheart development

ERBB3 SLIT2 MET SCUBE1 HEG1 TENM4 MEGF8 PKD1 LRP1 LRP2 TNFRSF1A FHL2 NOTCH1 NOTCH2

8.23e-0575711514GO:0007507
GeneOntologyBiologicalProcessaorta development

MEGF8 LRP1 LRP2 NOTCH1 NOTCH4

8.50e-05801155GO:0035904
GeneOntologyBiologicalProcesscellular response to tumor cell

NOTCH1 NOTCH2

9.21e-0531152GO:0071228
GeneOntologyBiologicalProcessregulation of apoptosis involved in tissue homeostasis

BIRC8 XIAP

9.21e-0531152GO:0060785
GeneOntologyBiologicalProcesspost-translational protein modification

BIRC8 RNF168 TRIM61 TRIM31 XIAP SIAH1 TRIM21 RNF114 TRIM10 MEGF8 HECTD2 CHFR NFX1 HERC1 RNF208 NSMCE1 TRIM60

9.38e-05107411517GO:0043687
GeneOntologyBiologicalProcessvasculature development

TSPAN12 LAMA1 GRN SLIT2 HEG1 PXDN MEGF8 PKD1 LRP1 LRP2 TNFRSF1A NOTCH1 NOTCH2 NOTCH3 NOTCH4 CCN3

9.44e-0596911516GO:0001944
GeneOntologyBiologicalProcessbasement membrane organization

LAMA1 LAMB1 PXDN HMCN1

9.57e-05431154GO:0071711
GeneOntologyBiologicalProcessartery development

MEGF8 LRP1 LRP2 NOTCH1 NOTCH3 NOTCH4

1.02e-041331156GO:0060840
GeneOntologyBiologicalProcessregulation of small GTPase mediated signal transduction

SPRY3 CDC42BPA GARNL3 SLIT2 MET HEG1 TIMP2 NOTCH1 NOTCH2

1.05e-043331159GO:0051056
GeneOntologyBiologicalProcesscardiac septum development

SLIT2 HEG1 LRP1 LRP2 NOTCH1 NOTCH2

1.06e-041341156GO:0003279
GeneOntologyBiologicalProcessregulation of extracellular matrix organization

LAMA1 LAMB1 LRP1 TNFRSF1A NOTCH1

1.07e-04841155GO:1903053
GeneOntologyBiologicalProcessanatomical structure homeostasis

TSPAN12 BIRC8 XIAP CUBN CRB1 USH2A MUC5AC MUC6 NOTCH1

1.07e-043341159GO:0060249
GeneOntologyBiologicalProcesstissue homeostasis

TSPAN12 BIRC8 XIAP CUBN CRB1 USH2A MUC5AC MUC6 NOTCH1

1.07e-043341159GO:0001894
GeneOntologyBiologicalProcessresponse to growth factor

SPRY3 FSTL3 CRIM1 XIAP ACVR1C LRP8 SLIT2 FBN2 MEGF8 LRP1 SCUBE3 LRP2 LTBP4 NOTCH1 NOTCH2

1.16e-0488311515GO:0070848
GeneOntologyBiologicalProcessbranching morphogenesis of an epithelial tube

LAMA1 LAMA5 SLIT2 MET PKD1 NOTCH1 NOTCH4

1.23e-041981157GO:0048754
GeneOntologyBiologicalProcessepithelial tube morphogenesis

LAMA1 LAMA5 SLIT2 MET MEGF8 PKD1 LRP2 NOTCH1 NOTCH2 NOTCH4

1.25e-0442111510GO:0060562
GeneOntologyBiologicalProcessregulation of muscle cell differentiation

LAMA1 LAMB1 NOTCH1 MEGF10 NOTCH2 NOTCH4 CCN3

1.27e-041991157GO:0051147
GeneOntologyBiologicalProcessregulation of neurogenesis

GSX2 LRP8 SLIT2 MET TENM4 MEGF8 LRP1 LRP2 ULK2 NOTCH1 NOTCH2

1.45e-0451511511GO:0050767
GeneOntologyBiologicalProcessgrowth

SIAH1 GRN ACVR1C SLIT2 SETDB1 NELL2 EYS HEG1 TENM4 MEGF8 LRP1 PTCH2 LTBP4 ULK2 NOTCH1 NOTCH2 CCN3 IL9

1.62e-04123511518GO:0040007
GeneOntologyBiologicalProcesssemi-lunar valve development

SLIT2 TNFRSF1A NOTCH1 NOTCH2

1.73e-04501154GO:1905314
GeneOntologyBiologicalProcessprotein maturation

BIRC8 XIAP GRN TMEM260 THBD FBLN1 NFYC CORIN LTBP4 DISP1 NOTCH4 PCSK9

1.77e-0461911512GO:0051604
GeneOntologyBiologicalProcesspulmonary valve morphogenesis

SLIT2 NOTCH1 NOTCH2

1.80e-04201153GO:0003184
GeneOntologyBiologicalProcessvenous blood vessel development

HEG1 NOTCH1 NOTCH4

1.80e-04201153GO:0060841
GeneOntologyBiologicalProcesspositive regulation of aorta morphogenesis

NOTCH1 NOTCH4

1.84e-0441152GO:1903849
GeneOntologyBiologicalProcessastrocyte activation involved in immune response

GRN LRP1

1.84e-0441152GO:0002265
GeneOntologyBiologicalProcessnegative regulation of extracellular matrix constituent secretion

TNFRSF1A NOTCH1

1.84e-0441152GO:0003332
GeneOntologyBiologicalProcesscardiac chamber development

SLIT2 HEG1 LRP1 LRP2 FHL2 NOTCH1 NOTCH2

1.88e-042121157GO:0003205
GeneOntologyBiologicalProcessregulation of nervous system development

GSX2 SLITRK3 LRP8 SLIT2 MET TENM4 MEGF8 LRP1 LRP2 ULK2 NOTCH1 NOTCH2

1.94e-0462511512GO:0051960
GeneOntologyBiologicalProcessnegative regulation of cellular response to growth factor stimulus

SPRY3 FSTL3 CRIM1 SLIT2 LRP2 NOTCH1

1.96e-041501156GO:0090288
GeneOntologyBiologicalProcessembryo implantation

LAMB1 GRN ACVR1C FBLN1 FBN2

2.11e-04971155GO:0007566
GeneOntologyBiologicalProcessnegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway

FSTL3 CRIM1 FBN2 LRP1 LRP2 NOTCH1 CCN3

2.23e-042181157GO:0090101
GeneOntologyBiologicalProcesskidney development

FRAS1 LAMA5 SLIT2 PKD1 LRP2 NOTCH1 NOTCH2 NOTCH3 PCSK9

2.40e-043721159GO:0001822
GeneOntologyBiologicalProcessendothelial cell differentiation

MET SCUBE1 HEG1 TNFRSF1A NOTCH1 NOTCH4

2.60e-041581156GO:0045446
GeneOntologyBiologicalProcesstube development

TSPAN12 CRISPLD2 LAMA1 LAMA5 GRN SLIT2 MET HEG1 PXDN MEGF8 PKD1 LRP1 LRP2 TNFRSF1A NOTCH1 NOTCH2 NOTCH3 NOTCH4 CCN3

2.66e-04140211519GO:0035295
GeneOntologyBiologicalProcessnegative regulation of viral process

TRIM31 TRIM21 TRIM10 SETDB1 FBLN1

2.80e-041031155GO:0048525
GeneOntologyBiologicalProcesscardiac chamber morphogenesis

SLIT2 HEG1 LRP2 FHL2 NOTCH1 NOTCH2

2.88e-041611156GO:0003206
GeneOntologyBiologicalProcesstrabecula morphogenesis

HEG1 FBN2 FHL2 NOTCH1

2.88e-04571154GO:0061383
GeneOntologyBiologicalProcessmuscle structure development

ERBB3 LAMA1 LAMA5 LAMB1 MET HEG1 LRP2 FHL2 DISP1 NOTCH1 MEGF10 NOTCH2 NOTCH4 CCN3

3.01e-0485811514GO:0061061
GeneOntologyBiologicalProcesspositive regulation of lysosomal protein catabolic process

LRP1 LRP2

3.05e-0451152GO:1905167
GeneOntologyBiologicalProcesschemoattraction of axon

LRP1 LRP2

3.05e-0451152GO:0061642
GeneOntologyBiologicalProcessterpenoid metabolic process

CYP2C9 CYP2C18 LRP8 LRP1 LRP2

3.06e-041051155GO:0006721
GeneOntologyBiologicalProcesslysosomal protein catabolic process

GRN LRP1 LRP2

3.14e-04241153GO:1905146
GeneOntologyBiologicalProcessresponse to wounding

ERBB3 VWF DGKE GRN LYST THBD FBLN1 SCUBE1 PROZ LRP1 NOTCH2 NOTCH4

3.14e-0465911512GO:0009611
GeneOntologyBiologicalProcessrenal system development

FRAS1 LAMA5 SLIT2 PKD1 LRP2 NOTCH1 NOTCH2 NOTCH3 PCSK9

3.15e-043861159GO:0072001
GeneOntologyBiologicalProcesspositive regulation of muscle cell differentiation

LAMA1 LAMB1 NOTCH1 NOTCH2 NOTCH4

3.20e-041061155GO:0051149
GeneOntologyBiologicalProcessextracellular matrix assembly

LAMB1 PXDN LTBP4 NOTCH1

3.29e-04591154GO:0085029
GeneOntologyBiologicalProcessregulation of viral transcription

TRIM31 TRIM21 NOTCH1

3.55e-04251153GO:0046782
GeneOntologyBiologicalProcessmorphogenesis of a branching epithelium

LAMA1 LAMA5 SLIT2 MET PKD1 NOTCH1 NOTCH4

3.61e-042361157GO:0061138
GeneOntologyBiologicalProcessembryo development

FRAS1 LAMA1 LAMA5 GRN CUBN ACVR1C SLIT2 SETDB1 THBD HEG1 FBN2 TENM4 MEGF8 PKD1 LRP2 OTOP1 DISP1 NOTCH1 NOTCH2

3.62e-04143711519GO:0009790
GeneOntologyBiologicalProcessregulation of Ras protein signal transduction

SPRY3 TIMP2 NOTCH1 NOTCH2

3.75e-04611154GO:0046578
GeneOntologyBiologicalProcesssensory system development

TSPAN12 LAMA1 LAMC3 GRN CRB1 DZANK1 PXDN ULK2 NOTCH1 NOTCH2

4.27e-0449111510GO:0048880
GeneOntologyBiologicalProcesswound healing

ERBB3 VWF DGKE LYST THBD FBLN1 SCUBE1 PROZ NOTCH2 NOTCH4

4.41e-0449311510GO:0042060
GeneOntologyBiologicalProcessglomerulus vasculature morphogenesis

NOTCH2 NOTCH3

4.56e-0461152GO:0072103
GeneOntologyBiologicalProcessglomerular capillary formation

NOTCH2 NOTCH3

4.56e-0461152GO:0072104
GeneOntologyBiologicalProcessregulation of aorta morphogenesis

NOTCH1 NOTCH4

4.56e-0461152GO:1903847
GeneOntologyBiologicalProcessepidermal cell fate specification

PTCH2 NOTCH1

4.56e-0461152GO:0009957
GeneOntologyBiologicalProcesscell-substrate adhesion

VWF LAMA5 LAMB1 ITGA9 SNED1 FBLN1 PKD1 LRP1 NOTCH1

4.88e-044101159GO:0031589
GeneOntologyCellularComponentextracellular matrix

CRISPLD2 LAMB4 FRAS1 VWF MATN3 LAMA1 LAMA5 LAMB1 LAMC3 SSPOP SNED1 SLIT2 FBLN1 EYS FBN2 PXDN HMCN1 TIMP2 GPC4 USH2A LTBP4 MUC5AC MUC6 CCN3 OTOG

1.49e-1465611525GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

CRISPLD2 LAMB4 FRAS1 VWF MATN3 LAMA1 LAMA5 LAMB1 LAMC3 SSPOP SNED1 SLIT2 FBLN1 EYS FBN2 PXDN HMCN1 TIMP2 GPC4 USH2A LTBP4 MUC5AC MUC6 CCN3 OTOG

1.60e-1465811525GO:0030312
GeneOntologyCellularComponentcollagen-containing extracellular matrix

LAMB4 FRAS1 VWF MATN3 LAMA1 LAMA5 LAMB1 LAMC3 SSPOP SLIT2 FBLN1 EYS FBN2 PXDN HMCN1 TIMP2 GPC4 USH2A LTBP4 CCN3

1.05e-1153011520GO:0062023
GeneOntologyCellularComponentcell surface

VWF SLITRK3 CUBN ACVR1C ITGA9 LRP8 SLIT2 MET THBD SCUBE1 HEG1 PXDN TIMP2 TEX101 PKD1 GPC4 LRP1 SCUBE3 LRP2 TNFRSF13B CORIN TNFRSF1A NOTCH1 NOTCH2 NOTCH3 NOTCH4 PCSK9

4.54e-11111111527GO:0009986
GeneOntologyCellularComponentbasement membrane

LAMB4 FRAS1 LAMA1 LAMA5 LAMB1 LAMC3 FBLN1 PXDN HMCN1 TIMP2 USH2A

7.22e-1112211511GO:0005604
GeneOntologyCellularComponentreceptor complex

ERBB3 INSRR CUBN ACVR1C ITGA9 LRP8 MET LRP1 LRP2 TNFRSF1A NOTCH1 NOTCH2 NOTCH3

1.89e-0558111513GO:0043235
GeneOntologyCellularComponentlaminin complex

LAMA1 LAMA5 LAMB1

1.89e-05101153GO:0043256
GeneOntologyCellularComponentlaminin-10 complex

LAMA5 LAMB1

8.97e-0531152GO:0043259
GeneOntologyCellularComponentlaminin-1 complex

LAMA1 LAMB1

8.97e-0531152GO:0005606
GeneOntologyCellularComponentexternal side of plasma membrane

VWF CUBN ITGA9 THBD SCUBE1 HEG1 GPC4 LRP1 LRP2 TNFRSF13B PCSK9

1.38e-0451911511GO:0009897
GeneOntologyCellularComponentextrinsic component of external side of plasma membrane

CUBN PCSK9

1.79e-0441152GO:0031232
GeneOntologyCellularComponentpostsynaptic density membrane

SLITRK3 CNKSR2 LRP8 LRP1 NOTCH1

1.77e-031571155GO:0098839
GeneOntologyCellularComponentmicrofibril

FBN2 LTBP4

2.25e-03131152GO:0001527
MousePhenomicrognathia

FRAS1 TRPS1 FBLN1 FBN2 MEGF8 PKD1 LRP2

4.91e-0768997MP:0002639
MousePhenoabnormal heart septum morphology

FRAS1 CRIM1 LAMA5 SLIT2 FBLN1 HEG1 MEGF8 PKD1 LRP1 SCUBE3 LRP2 LTBP4 CCN3

3.38e-063889913MP:0006113
MousePhenoabnormal interventricular septum morphology

FRAS1 CRIM1 LAMA5 SLIT2 FBLN1 HEG1 MEGF8 PKD1 SCUBE3 LRP2 LTBP4 CCN3

5.19e-063429912MP:0000281
MousePhenoabnormal kidney morphology

FRAS1 CRIM1 TRIM61 TRPS1 LAMA5 GRN LYST SLC26A1 SLIT2 MET NELL1 THBD FBLN1 FBN2 MEGF8 TIMP2 FAM72A PKD1 CHFR LRP2 TNFRSF13B NOTCH2 NOTCH3 CCN3 IL9

6.36e-0613639925MP:0002135
MousePhenoabnormal kidney vasculature morphology

FRAS1 CRIM1 LAMA5 FBLN1 NOTCH2 CCN3

1.26e-0573996MP:0000530
MousePhenoabnormal glomerular capillary endothelium morphology

CRIM1 LAMA5 FBLN1 NOTCH2

1.29e-0521994MP:0011453
MousePhenointernal hemorrhage

TSPAN12 BIRC8 FRAS1 VWF CRIM1 XIAP DZANK1 FBLN1 HEG1 PKD1 LRP1 NOTCH1

1.80e-053879912MP:0001634
MousePhenoabnormal respiration

FRAS1 ERBB3 TRPS1 GSX2 ITGA9 MET NELL1 FBLN1 PKD1 CHFR SCUBE3 LRP2 TNFRSF1A LTBP4 DISP1

1.90e-055989915MP:0001943
MousePhenoabnormal glomerular capillary morphology

FRAS1 CRIM1 LAMA5 FBLN1 NOTCH2

1.95e-0547995MP:0011320
MousePhenoabnormal kidney capillary morphology

FRAS1 CRIM1 LAMA5 FBLN1 NOTCH2

2.16e-0548995MP:0011310
MousePhenoabnormal nephron morphology

FRAS1 CRIM1 TRPS1 LAMA5 GRN LYST MET FBLN1 PKD1 LRP2 TNFRSF13B NOTCH2

4.62e-054269912MP:0003881
MousePhenoabnormal ureteric bud morphology

FRAS1 TRPS1 LAMA5 SLIT2 NOTCH2

5.03e-0557995MP:0006032
MousePhenoabnormal respiratory system physiology

FRAS1 ERBB3 TRPS1 GSX2 ITGA9 LYST MET NELL1 FBLN1 HEG1 PKD1 CHFR SCUBE3 LRP2 TNFRSF1A LTBP4 DISP1 RNF208

5.15e-058979918MP:0002133
MousePhenoabnormal pectoral girdle bone morphology

FRAS1 TRPS1 DGKE SSPOP FBN2 TENM4 MEGF8 HECTD2 SCUBE3 LTBP4

5.29e-053019910MP:0004508
MousePhenoabnormal ocular fundus morphology

TSPAN12 LAMA1 TRIM31 ZDHHC14 LAMC3 GRN RXFP3 LYST CRB1 NELL1 FBN2 PXDN HMCN1 TIMP2 GJC3 HERC1 USH2A NOTCH1 MEGF10 NOTCH3 NOTCH4 NSMCE1

5.69e-0512629922MP:0002864
MousePhenoabnormal heart size

RNF168 FSTL3 LAMA5 ACVR1C TRIM10 SLIT2 FBLN1 FBN2 TENM4 MEGF8 PKD1 LRP1 LRP2 CORIN TNFRSF1A FHL2 LTBP4 NOTCH1 RNF208 NOTCH2 NOTCH3

6.46e-0511809921MP:0005406
MousePhenoabnormal somatic nervous system morphology

ERBB3 CRIM1 GSX2 LAMC3 GRN CRB1 MET FBLN1 SCUBE1 FBN2 PXDN HMCN1 MEGF8 OTOP1 USH2A DISP1 NOTCH1 MEGF10 OTOG

9.00e-0510259919MP:0002752
MousePhenoventricular septal defect

FRAS1 CRIM1 LAMA5 SLIT2 FBLN1 HEG1 MEGF8 PKD1 LRP2

9.61e-05261999MP:0010402
MousePhenoabnormal renal/urinary system physiology

CRIM1 LAMA5 GRN TRIM21 LYST SLC26A1 SLC5A2 MET PKD1 SCUBE3 LRP2 TNFRSF13B CORIN RXFP4 NOTCH2

1.06e-046959915MP:0005502
MousePhenoabnormal urine homeostasis

CRIM1 LAMA5 GRN TRIM21 LYST SLC26A1 SLC5A2 SCUBE3 LRP2 TNFRSF13B CORIN RXFP4

1.09e-044669912MP:0009643
MousePhenoabnormal vertebral column morphology

FRAS1 RNF168 CRIM1 TRIM61 TRPS1 SSPOP NELL1 FBLN1 FBN2 TENM4 PKD1 SCUBE3 NOTCH1 NOTCH2 NOTCH3 CCN3

1.22e-047879916MP:0004703
MousePhenooverexpanded pulmonary alveolus

LYST FBLN1 LRP2 LTBP4

1.31e-0437994MP:0001183
MousePhenoabnormal heart ventricle morphology

FRAS1 CRIM1 LAMA5 RXFP3 SLIT2 FBLN1 HEG1 MEGF8 PKD1 CHFR LRP1 SCUBE3 LRP2 LTBP4 NOTCH1 CCN3

1.34e-047939916MP:0005294
MousePhenoabnormal kidney size

FRAS1 CRIM1 TRIM61 LAMA5 GRN LYST SLIT2 NELL1 MEGF8 PKD1 CHFR NOTCH2 NOTCH3 CCN3 IL9

1.42e-047149915MP:0002706
MousePhenoabnormal axial skeleton morphology

FRAS1 RNF168 CRIM1 TRIM61 TRPS1 LAMA5 DGKE SSPOP NELL1 FBLN1 SCUBE1 FBN2 TENM4 MEGF8 PKD1 SCUBE3 LRP2 LTBP4 DISP1 NOTCH1 NOTCH2 NOTCH3 CCN3

1.71e-0414589923MP:0002114
MousePhenoabnormal aorta morphology

CRIM1 LAMA5 SLIT2 FBLN1 MEGF8 PKD1 LRP2 LTBP4

1.94e-04225998MP:0000272
MousePhenoabnormal aortic arch morphology

CRIM1 LAMA5 SLIT2 FBLN1 MEGF8 LRP2

1.97e-04119996MP:0004113
MousePhenoabnormal blood vessel morphology

TSPAN12 FRAS1 CRIM1 LAMA1 TRIM31 LAMA5 CUBN CRB1 SLIT2 MET FBLN1 MEGF8 PKD1 LRP2 GJC3 LTBP4 DISP1 NOTCH1 NOTCH2 NOTCH3 NOTCH4 CCN3 NSMCE1

1.97e-0414729923MP:0001614
MousePhenoabnormal urine protein level

CRIM1 LAMA5 TRIM21 SCUBE3 LRP2 TNFRSF13B CORIN

2.02e-04170997MP:0006315
MousePhenomuscular ventricular septal defect

CRIM1 SLIT2 FBLN1 MEGF8 LRP2

2.12e-0477995MP:0010420
MousePhenohypolactation

BIRC8 ERBB3 XIAP

2.18e-0417993MP:0013716
MousePhenoabnormal interventricular septum muscular part morphology

CRIM1 SLIT2 FBLN1 MEGF8 LRP2

2.40e-0479995MP:0010498
MousePhenomicrophthalmia

FRAS1 RNF168 CRIM1 LAMA5 SLIT2 PXDN MEGF8 LRP1 LRP2 NOTCH2

2.41e-043629910MP:0001297
MousePhenokidney cyst

FRAS1 CRIM1 LAMA5 SLIT2 FAM72A PKD1 LRP2

2.59e-04177997MP:0003675
MousePhenoabnormal anterior eye segment morphology

RNF168 CRIM1 LAMA1 ZDHHC14 CUBN LYST SLIT2 NELL1 FBN2 TENM4 PXDN HMCN1 GPC4 LRP1 HERC1 MUC5AC NOTCH1 CCN3 IL9

2.75e-0411179919MP:0005193
MousePhenoabnormal blood circulation

TSPAN12 BIRC8 FRAS1 ERBB3 VWF CRIM1 XIAP ITGA9 DZANK1 FBLN1 HEG1 PKD1 LRP1 NOTCH1 NOTCH2 NOTCH3

2.75e-048459916MP:0002128
MousePhenoabnormal branching involved in ureteric bud morphogenesis

FRAS1 TRPS1 LAMA5 NOTCH2

2.82e-0445994MP:0010981
MousePhenoabnormal pericardial cavity morphology

BIRC8 XIAP HEG1 PKD1 DISP1 NOTCH2

2.93e-04128996MP:0012501
MousePhenofetal bleb

FRAS1 CRIM1

2.95e-044992MP:0008856
MousePhenoabnormal ophthalmic nerve morphology

ERBB3 MEGF8

2.95e-044992MP:0009798
MousePhenoabnormal kidney physiology

CRIM1 LAMA5 GRN SLC26A1 SLC5A2 MET PKD1 SCUBE3 TNFRSF13B NOTCH2

3.00e-043729910MP:0002136
MousePhenoabnormal glomerular mesangium morphology

FRAS1 CRIM1 LAMA5 TNFRSF13B NOTCH2

3.02e-0483995MP:0011339
MousePhenoabnormal eye size

FRAS1 RNF168 CRIM1 LAMA5 SLIT2 PXDN MEGF8 LRP1 LRP2 NOTCH2

3.19e-043759910MP:0002697
MousePhenoabnormal retina morphology

TSPAN12 LAMA1 TRIM31 ZDHHC14 LAMC3 GRN RXFP3 LYST CRB1 NELL1 PXDN TIMP2 GJC3 HERC1 USH2A NOTCH1 MEGF10 NOTCH3 NOTCH4 NSMCE1

3.25e-0412279920MP:0001325
MousePhenohemopericardium

BIRC8 XIAP HEG1 PKD1

3.34e-0447994MP:0005244
MousePhenoanophthalmia

RNF168 GARNL3 LAMA5 TENM4 PXDN MEGF8 LRP2 CCN3

3.54e-04246998MP:0001293
MousePhenoabnormal thoracic aorta morphology

CRIM1 LAMA5 SLIT2 FBLN1 MEGF8 LRP2

3.75e-04134996MP:0010468
MousePhenoabnormal vertebrae morphology

FRAS1 RNF168 CRIM1 TRIM61 NELL1 FBN2 TENM4 PKD1 SCUBE3 NOTCH1 NOTCH2 CCN3

4.67e-045469912MP:0000137
MousePhenoabnormal kidney cortex morphology

FRAS1 CRIM1 TRPS1 LAMA5 MET FBLN1 PKD1 TNFRSF13B NOTCH2

4.80e-04324999MP:0000521
MousePhenoabnormal ear morphology

TSPAN12 LAMA5 LYST FBLN1 FBN2 SCUBE3 LRP2 OTOP1 USH2A NOTCH1 OTOG

4.83e-044709911MP:0002102
MousePhenoperimembraneous ventricular septal defect

FRAS1 CRIM1 SLIT2 FBLN1 LRP2

4.86e-0492995MP:0010418
MousePhenoventricular cardiomyopathy

LTBP4 CCN3

4.90e-045992MP:0002952
MousePhenoabnormal interdigital cell death

FRAS1 FBN2

4.90e-045992MP:0009874
MousePhenoabnormal interventricular septum membranous part morphology

FRAS1 CRIM1 SLIT2 FBLN1 LRP2

5.11e-0493995MP:0008823
MousePhenosyndactyly

FRAS1 CRIM1 LAMA5 FBN2 SCUBE3

5.11e-0493995MP:0000564
MousePhenoabnormal capillary morphology

FRAS1 CRIM1 LAMA5 FBLN1 NOTCH2

5.11e-0493995MP:0003658
MousePhenoabnormal respiratory function

FRAS1 TRPS1 GSX2 ITGA9 FBLN1 PKD1 SCUBE3 TNFRSF1A LTBP4 DISP1

5.20e-043999910MP:0002327
MousePhenoabnormal craniofacial morphology

FRAS1 RNF168 CRIM1 TRPS1 LAMA5 GSX2 LYST MET NELL1 FBLN1 SCUBE1 FBN2 MEGF8 PKD1 GPC4 LRP1 SCUBE3 LRP2 DISP1 NOTCH1 CCN3

5.24e-0413729921MP:0000428
MousePhenocraniofacial phenotype

FRAS1 RNF168 CRIM1 TRPS1 LAMA5 GSX2 LYST MET NELL1 FBLN1 SCUBE1 FBN2 MEGF8 PKD1 GPC4 LRP1 SCUBE3 LRP2 DISP1 NOTCH1 CCN3

5.24e-0413729921MP:0005382
MousePhenoabnormal susceptibility to induced thrombosis

VWF THBD SCUBE1 PROZ

5.31e-0453994MP:0020408
MousePhenoabnormal tail morphology

FRAS1 TRIM61 LAMA5 LAMB1 LYST FBN2 PXDN SCUBE3 LRP2 CCN3

5.62e-044039910MP:0002111
MousePhenoabnormal renal glomerulus morphology

FRAS1 CRIM1 TRPS1 LAMA5 MET FBLN1 TNFRSF13B NOTCH2

5.66e-04264998MP:0005325
MousePhenoabnormal cranium morphology

FRAS1 RNF168 CRIM1 TRPS1 LAMA5 NELL1 FBLN1 SCUBE1 FBN2 MEGF8 PKD1 SCUBE3 LRP2 DISP1 CCN3

5.72e-048139915MP:0000438
MousePhenoheart hemorrhage

BIRC8 XIAP HEG1 PKD1

6.12e-0455994MP:0009698
MousePhenofused cornea and lens

RNF168 CUBN PXDN

6.26e-0424993MP:0001307
MousePhenoabnormal neurocranium morphology

TRPS1 LAMA5 NELL1 FBLN1 SCUBE1 PKD1 SCUBE3 DISP1

6.40e-04269998MP:0000074
MousePhenoincreased urine protein level

CRIM1 LAMA5 TRIM21 LRP2 TNFRSF13B CORIN

6.58e-04149996MP:0002962
MousePhenoabnormal craniofacial bone morphology

FRAS1 RNF168 CRIM1 TRPS1 LAMA5 NELL1 FBLN1 SCUBE1 FBN2 MEGF8 PKD1 SCUBE3 LRP2 DISP1 CCN3

6.83e-048279915MP:0002116
MousePhenoabnormal eye vasculature morphology

TSPAN12 LAMA1 TRIM31 CRB1 GJC3 NOTCH1 NOTCH2 NOTCH3 NOTCH4 NSMCE1

7.06e-044159910MP:0031346
MousePhenoeffusion

BIRC8 XIAP ITGA9 HEG1 PKD1 NOTCH2

7.31e-04152996MP:0021205
MousePhenohemorrhage

TSPAN12 BIRC8 FRAS1 VWF CRIM1 XIAP DZANK1 FBLN1 HEG1 PKD1 LRP1 NOTCH1 NOTCH2

7.98e-046649913MP:0001914
MousePhenoabnormal vitreous body morphology

TSPAN12 LAMA1 ZDHHC14 RXFP3 SLIT2 NELL1 PXDN NOTCH2 CCN3 IL9

9.09e-044299910MP:0002699
MousePhenocornea opacity

RNF168 FBN2 TENM4 PXDN GPC4 MUC5AC

9.24e-04159996MP:0001314
MousePhenoabnormal thrombosis

VWF THBD SCUBE1 PROZ NOTCH3

9.27e-04106995MP:0005048
MousePhenoabnormal renal glomerular capsule morphology

FRAS1 CRIM1 LAMA5 FBLN1 NOTCH2

9.67e-04107995MP:0002828
MousePhenoabnormal mandibular nerve morphology

ERBB3 CRIM1

1.02e-037992MP:0009800
MousePhenoincreased hindbrain apoptosis

FBLN1 MEGF10

1.02e-037992MP:0012261
MousePhenoabnormal pericardium morphology

BIRC8 XIAP HEG1 PKD1 DISP1 NOTCH1 NOTCH2

1.08e-03225997MP:0000288
MousePhenoabnormal parietal bone morphology

NELL1 FBLN1 SCUBE1 DISP1

1.09e-0364994MP:0000109
MousePhenoabnormal artery morphology

CRIM1 LAMA5 SLIT2 FBLN1 MEGF8 PKD1 LRP2 LTBP4 NOTCH1 NOTCH3

1.10e-034409910MP:0002191
MousePhenoabnormal renal corpuscle morphology

FRAS1 CRIM1 TRPS1 LAMA5 MET FBLN1 TNFRSF13B NOTCH2

1.11e-03293998MP:0002827
MousePhenoabnormal urinary system development

FRAS1 TRPS1 LAMA5 SLIT2 NOTCH2

1.14e-03111995MP:0003942
MousePhenopericardial effusion

BIRC8 XIAP HEG1 PKD1 NOTCH2

1.14e-03111995MP:0005312
MousePhenolimbs/digits/tail phenotype

FRAS1 CRIM1 TRIM61 MATN3 LAMA5 LAMB1 LYST MET FBN2 PXDN MEGF8 TIMP2 PKD1 LRP1 SCUBE3 LRP2 DISP1 NOTCH2 CCN3

1.19e-0312589919MP:0005371
MousePhenoabnormal intestinal goblet cell morphology

LAMA5 LTBP4 MUC5AC IL9

1.22e-0366994MP:0003449
MousePhenoabnormal lens morphology

RNF168 CRIM1 LAMA1 ZDHHC14 CUBN SLIT2 NELL1 PXDN HMCN1 LRP1 HERC1 CCN3 IL9

1.28e-036999913MP:0001303
MousePhenoabnormal kidney interstitium morphology

CRIM1 TRPS1 LAMA5 PKD1

1.29e-0367994MP:0011425
MousePhenoabnormal somatic sensory system morphology

ERBB3 CRIM1 GSX2 LAMC3 GRN CRB1 SCUBE1 PXDN USH2A DISP1 NOTCH1 MEGF10 OTOG

1.33e-037029913MP:0000959
MousePhenokidney inflammation

CRIM1 GRN SLC26A1 MET PKD1 TNFRSF13B

1.35e-03171996MP:0001859
MousePhenoabnormal left-right axis symmetry of the somites

DISP1 NOTCH1

1.35e-038992MP:0005224
MousePhenoabnormal retina inner limiting membrane morphology

LAMA1 PXDN

1.35e-038992MP:0010235
MousePhenoabnormal retina blood vessel morphology

LAMA1 TRIM31 GJC3 NOTCH1 NOTCH3 NOTCH4 NSMCE1

1.36e-03234997MP:0010097
MousePhenoabnormal breathing pattern

TRPS1 GSX2 ITGA9 FBLN1 PKD1 SCUBE3 LTBP4 DISP1

1.38e-03303998MP:0001951
MousePhenoabnormal systemic artery morphology

CRIM1 LAMA5 SLIT2 FBLN1 MEGF8 PKD1 LRP2 LTBP4

1.41e-03304998MP:0011655
MousePhenoabnormal bone structure

CRISPLD2 CYP2C9 MATN3 TRPS1 CNKSR2 SLC5A2 NELL1 FBN2 TENM4 TIMP2 HECTD2 PKD1 SCUBE3 LRP2 TNFRSF1A HERC1 FHL2 NOTCH2 NOTCH3 CCN3

1.42e-0313799920MP:0003795
MousePhenoabnormal lung size

TRPS1 LAMA5 THBD FBLN1 PKD1 LTBP4

1.47e-03174996MP:0004881
MousePhenoabnormal urine magnesium level

GRN SLC5A2 RXFP4

1.47e-0332993MP:0011434
MousePhenoabnormal urine creatinine level

GRN SLC5A2 SCUBE3

1.47e-0332993MP:0011469
MousePhenoperinatal lethality, complete penetrance

ERBB3 CRIM1 TRPS1 GSX2 MET NELL1 FBLN1 SCUBE1 PKD1 LRP1 LRP2 DISP1 NOTCH2

1.51e-037129913MP:0011089
MousePhenoabnormal cardiovascular development

ERBB3 CRIM1 LAMA5 CUBN THBD FBLN1 HEG1 MEGF8 PKD1 LRP2 DISP1 NOTCH1 NOTCH3 CCN3

1.51e-038029914MP:0002925
DomainGrowth_fac_rcpt_

FRAS1 ERBB3 CRIM1 MATN3 LAMA1 INSRR LAMA5 LAMB1 LAMC3 CUBN CRB1 LRP8 NELL1 THBD FBLN1 NELL2 EYS SCUBE1 FBN2 HMCN1 MEGF8 LRP1 SCUBE3 LRP2 LTBP4 NOTCH1 NOTCH2 NOTCH3 NOTCH4 CCN3

5.24e-3715611530IPR009030
DomainEGF-like_dom

FRAS1 MATN3 LAMA1 LAMA5 LAMB1 LAMC3 CUBN CRB1 LRP8 SNED1 SLIT2 NELL1 THBD FBLN1 NELL2 EYS SCUBE1 HEG1 FBN2 PROZ TENM4 HMCN1 MEGF8 LRP1 SCUBE3 LRP2 C8B LTBP4 NOTCH1 MEGF10 NOTCH2 NOTCH3 NOTCH4 OTOG

1.17e-3624911534IPR000742
DomainEGF_1

LAMB4 LAMA1 LAMA5 LAMB1 LAMC3 CUBN SSPOP CRB1 LRP8 SNED1 SLIT2 NELL1 THBD FBLN1 NELL2 EYS SCUBE1 HEG1 FBN2 PROZ TENM4 HMCN1 MEGF8 LRP1 SCUBE3 LRP2 C8B USH2A LTBP4 NOTCH1 MEGF10 NOTCH2 NOTCH3 NOTCH4

2.72e-3625511534PS00022
DomainEGF_2

LAMB4 MATN3 LAMA1 LAMA5 LAMB1 LAMC3 CUBN SSPOP CRB1 LRP8 SNED1 SLIT2 NELL1 THBD FBLN1 NELL2 EYS SCUBE1 HEG1 FBN2 PROZ TENM4 HMCN1 MEGF8 LRP1 SCUBE3 LRP2 C8B LTBP4 NOTCH1 MEGF10 NOTCH2 NOTCH3 NOTCH4

1.06e-3526511534PS01186
DomainEGF

FRAS1 MATN3 LAMA1 LAMA5 LAMB1 LAMC3 CUBN CRB1 LRP8 SNED1 SLIT2 NELL1 THBD FBLN1 NELL2 EYS SCUBE1 HEG1 FBN2 PROZ TENM4 HMCN1 MEGF8 LRP1 SCUBE3 LRP2 LTBP4 NOTCH1 MEGF10 NOTCH2 NOTCH3 NOTCH4

2.04e-3423511532SM00181
DomainEGF-like_CS

LAMB4 MATN3 LAMA1 LAMA5 LAMB1 LAMC3 CUBN CRB1 LRP8 SNED1 SLIT2 NELL1 THBD FBLN1 NELL2 EYS SCUBE1 HEG1 FBN2 PROZ TENM4 HMCN1 MEGF8 LRP1 SCUBE3 LRP2 C8B LTBP4 NOTCH1 MEGF10 NOTCH2 NOTCH3 NOTCH4

2.07e-3426111533IPR013032
DomainASX_HYDROXYL

CUBN CRB1 LRP8 SNED1 SLIT2 NELL1 THBD FBLN1 NELL2 EYS SCUBE1 HEG1 FBN2 PROZ HMCN1 MEGF8 LRP1 SCUBE3 LRP2 LTBP4 NOTCH1 NOTCH2 NOTCH3 NOTCH4

3.77e-3210011524PS00010
DomainEGF_CA

MATN3 CUBN CRB1 LRP8 SNED1 SLIT2 NELL1 THBD FBLN1 NELL2 EYS SCUBE1 HEG1 FBN2 PROZ HMCN1 MEGF8 LRP1 SCUBE3 LRP2 LTBP4 NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.39e-3112211525SM00179
DomainEGF-type_Asp/Asn_hydroxyl_site

CUBN CRB1 LRP8 SNED1 SLIT2 NELL1 THBD FBLN1 NELL2 EYS SCUBE1 HEG1 FBN2 PROZ HMCN1 MEGF8 LRP1 SCUBE3 LRP2 LTBP4 NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.79e-3110611524IPR000152
DomainEGF-like_Ca-bd_dom

MATN3 CUBN CRB1 LRP8 SNED1 SLIT2 NELL1 THBD FBLN1 NELL2 EYS SCUBE1 HEG1 FBN2 PROZ HMCN1 MEGF8 LRP1 SCUBE3 LRP2 LTBP4 NOTCH1 NOTCH2 NOTCH3 NOTCH4

2.16e-3112411525IPR001881
DomainEGF_3

MATN3 CUBN SSPOP CRB1 LRP8 SNED1 SLIT2 NELL1 THBD FBLN1 NELL2 EYS SCUBE1 HEG1 FBN2 PROZ TENM4 HMCN1 MEGF8 LRP1 SCUBE3 LRP2 C8B LTBP4 NOTCH1 MEGF10 NOTCH2 NOTCH3 NOTCH4 OTOG

2.29e-3123511530PS50026
DomainEGF_Ca-bd_CS

CUBN CRB1 LRP8 SNED1 SLIT2 NELL1 THBD FBLN1 NELL2 EYS SCUBE1 HEG1 FBN2 HMCN1 MEGF8 LRP1 SCUBE3 LRP2 LTBP4 NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.09e-309711523IPR018097
DomainEGF_CA

CUBN CRB1 LRP8 SNED1 SLIT2 NELL1 THBD FBLN1 NELL2 EYS SCUBE1 HEG1 FBN2 HMCN1 MEGF8 LRP1 SCUBE3 LRP2 LTBP4 NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.83e-309911523PS01187
DomainEGF_CA

MATN3 CUBN LRP8 NELL1 THBD FBLN1 NELL2 SCUBE1 HEG1 FBN2 HMCN1 MEGF8 LRP1 SCUBE3 LRP2 LTBP4 NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.42e-268611520PF07645
DomainEGF

MATN3 CUBN CRB1 LRP8 SNED1 SLIT2 THBD EYS HEG1 PROZ HMCN1 LRP1 SCUBE3 LRP2 NOTCH1 NOTCH2 NOTCH3 NOTCH4

6.57e-2012611518PF00008
DomainhEGF

CRB1 SNED1 SLIT2 EYS FBN2 NOTCH1 MEGF10 NOTCH2 NOTCH3 NOTCH4

6.28e-162811510PF12661
DomainVWC_out

FRAS1 VWF CRIM1 SSPOP NELL1 NELL2 MUC5AC MUC6 OTOG

8.11e-16191159SM00215
DomainVWF_dom

FRAS1 VWF CRIM1 SSPOP NELL1 NELL2 PXDN MUC5AC MUC6 CCN3 OTOG

1.08e-154211511IPR001007
DomainVWFC_1

FRAS1 VWF CRIM1 SSPOP NELL1 NELL2 PXDN MUC5AC CCN3

7.58e-13361159PS01208
DomainVWFC_2

FRAS1 VWF CRIM1 SSPOP NELL1 NELL2 PXDN MUC5AC CCN3

1.30e-12381159PS50184
DomainVWC

FRAS1 VWF CRIM1 SSPOP NELL1 NELL2 PXDN MUC5AC CCN3

1.30e-12381159SM00214
DomaincEGF

THBD FBLN1 SCUBE1 FBN2 HMCN1 LRP1 SCUBE3 LRP2

2.30e-12261158PF12662
DomaincEGF

THBD FBLN1 SCUBE1 FBN2 HMCN1 LRP1 SCUBE3 LRP2

2.30e-12261158IPR026823
DomainVWC

FRAS1 VWF CRIM1 NELL1 NELL2 PXDN MUC5AC CCN3

4.53e-12281158PF00093
DomainEGF_Lam

LAMB4 LAMA1 LAMA5 LAMB1 LAMC3 MEGF8 USH2A MEGF10

3.31e-11351158SM00180
DomainLaminin_EGF

LAMB4 LAMA1 LAMA5 LAMB1 LAMC3 MEGF8 USH2A MEGF10

3.31e-11351158PF00053
DomainLaminin_EGF

LAMB4 LAMA1 LAMA5 LAMB1 LAMC3 MEGF8 USH2A MEGF10

6.77e-11381158IPR002049
DomainLaminin_G_2

LAMA1 LAMA5 CRB1 SLIT2 NELL1 NELL2 EYS USH2A

1.05e-10401158PF02210
DomainCys_knot_C

VWF SSPOP SLIT2 MUC5AC MUC6 CCN3 OTOG

1.22e-10251157IPR006207
DomainCTCK_2

VWF SSPOP SLIT2 MUC5AC MUC6 CCN3 OTOG

1.22e-10251157PS01225
DomainTIL_dom

VWF SSPOP LRP2 MUC5AC MUC6 OTOG

1.38e-10141156IPR002919
DomainLamG

LAMA1 LAMA5 CRB1 SLIT2 NELL1 NELL2 EYS USH2A

2.38e-10441158SM00282
DomainLaminin_N

LAMB4 LAMA1 LAMA5 LAMB1 LAMC3 USH2A

3.64e-10161156IPR008211
DomainLamNT

LAMB4 LAMA1 LAMA5 LAMB1 LAMC3 USH2A

3.64e-10161156SM00136
DomainLAMININ_NTER

LAMB4 LAMA1 LAMA5 LAMB1 LAMC3 USH2A

3.64e-10161156PS51117
DomainLaminin_N

LAMB4 LAMA1 LAMA5 LAMB1 LAMC3 USH2A

3.64e-10161156PF00055
DomainLDLRA_1

SSPOP MAMDC4 LRP8 PKD1 LRP1 LRP2 CORIN C8B

4.96e-10481158PS01209
DomainEGF_LAM_2

LAMB4 LAMA1 LAMA5 LAMB1 LAMC3 MEGF8 USH2A

5.05e-10301157PS50027
DomainEGF_LAM_1

LAMB4 LAMA1 LAMA5 LAMB1 LAMC3 MEGF8 USH2A

5.05e-10301157PS01248
DomainLDLRA_2

SSPOP MAMDC4 LRP8 PKD1 LRP1 LRP2 CORIN C8B

5.90e-10491158PS50068
DomainConA-like_dom

LAMA1 LAMA5 TRIM21 MAMDC4 CRB1 TRIM10 SLIT2 NELL1 NELL2 EYS HERC1 USH2A TRIM60

9.45e-1021911513IPR013320
DomainNotch

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.36e-0941154IPR008297
DomainNODP

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.36e-0941154PF07684
DomainNotch_NODP_dom

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.36e-0941154IPR011656
DomainNotch_NOD_dom

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.36e-0941154IPR010660
DomainNOD

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.36e-0941154PF06816
DomainNOD

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.36e-0941154SM01338
DomainNODP

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.36e-0941154SM01339
DomainLaminin_G

LAMA1 LAMA5 CRB1 SLIT2 NELL1 NELL2 EYS USH2A

2.40e-09581158IPR001791
DomainCT

VWF SLIT2 MUC5AC MUC6 CCN3 OTOG

3.29e-09221156SM00041
DomainLDLR_class-A_CS

SSPOP MAMDC4 LRP8 LRP1 LRP2 CORIN C8B

4.40e-09401157IPR023415
DomainEGF_dom

CUBN NELL1 SCUBE1 MEGF8 SCUBE3

6.20e-09121155IPR024731
DomainC8

VWF SSPOP MUC5AC MUC6 OTOG

6.20e-09121155PF08742
DomainEGF_3

CUBN NELL1 SCUBE1 MEGF8 SCUBE3

6.20e-09121155PF12947
DomainTIL

VWF SSPOP MUC5AC MUC6 OTOG

6.20e-09121155PF01826
DomainLNR

NOTCH1 NOTCH2 NOTCH3 NOTCH4

6.79e-0951154PS50258
DomainUnchr_dom_Cys-rich

VWF SSPOP MUC5AC MUC6 OTOG

1.00e-08131155IPR014853
DomainC8

VWF SSPOP MUC5AC MUC6 OTOG

1.00e-08131155SM00832
DomainLdl_recept_a

SSPOP MAMDC4 LRP8 LRP1 LRP2 CORIN C8B

1.04e-08451157PF00057
DomainZnf_RING

BIRC8 RNF168 TRIM61 TRIM31 XIAP SIAH1 TRIM21 RNF114 TRIM10 CHFR NFX1 RNF208 NSMCE1 TRIM60

1.34e-0832611514IPR001841
DomainLDrepeatLR_classA_rpt

SSPOP MAMDC4 LRP8 LRP1 LRP2 CORIN C8B

1.94e-08491157IPR002172
DomainLDLa

SSPOP MAMDC4 LRP8 LRP1 LRP2 CORIN C8B

1.94e-08491157SM00192
DomainZF_RING_1

BIRC8 RNF168 TRIM61 TRIM31 XIAP SIAH1 TRIM21 RNF114 TRIM10 CHFR NFX1 RNF208 TRIM60

2.88e-0829111513PS00518
DomainVWF_type-D

VWF SSPOP MUC5AC MUC6 OTOG

3.36e-08161155IPR001846
DomainVWFD

VWF SSPOP MUC5AC MUC6 OTOG

3.36e-08161155PS51233
DomainVWD

VWF SSPOP MUC5AC MUC6 OTOG

3.36e-08161155SM00216
DomainVWD

VWF SSPOP MUC5AC MUC6 OTOG

3.36e-08161155PF00094
DomainZF_RING_2

BIRC8 RNF168 TRIM61 TRIM31 XIAP SIAH1 TRIM21 RNF114 TRIM10 CHFR NFX1 RNF208 TRIM60

3.82e-0829811513PS50089
DomainNotch_dom

NOTCH1 NOTCH2 NOTCH3 NOTCH4

4.71e-0871154IPR000800
DomainNotch

NOTCH1 NOTCH2 NOTCH3 NOTCH4

4.71e-0871154PF00066
DomainNL

NOTCH1 NOTCH2 NOTCH3 NOTCH4

4.71e-0871154SM00004
DomainRING

BIRC8 RNF168 TRIM61 TRIM31 XIAP SIAH1 TRIM21 RNF114 TRIM10 CHFR NFX1 RNF208 TRIM60

5.01e-0830511513SM00184
DomainCTCK_1

VWF SSPOP SLIT2 MUC5AC CCN3

6.52e-08181155PS01185
DomainEGF_extracell

NELL1 NELL2 TENM4 LRP2 NOTCH1 MEGF10 NOTCH3

8.23e-08601157IPR013111
DomainEGF_2

NELL1 NELL2 TENM4 LRP2 NOTCH1 MEGF10 NOTCH3

8.23e-08601157PF07974
DomainLAM_G_DOMAIN

LAMA1 LAMA5 CRB1 SLIT2 EYS USH2A

1.12e-07381156PS50025
Domain-

LAMA1 LAMA5 CRB1 SLIT2 NELL1 NELL2 EYS USH2A

1.26e-079511582.60.120.200
DomainDUF3454

NOTCH1 NOTCH2 NOTCH3

2.27e-0731153PF11936
DomainDUF3454_notch

NOTCH1 NOTCH2 NOTCH3

2.27e-0731153IPR024600
DomainDUF3454

NOTCH1 NOTCH2 NOTCH3

2.27e-0731153SM01334
Domain-

SSPOP MAMDC4 LRP8 LRP1 LRP2 CORIN

3.66e-074611564.10.400.10
Domainzf-C3HC4

BIRC8 RNF168 TRIM61 TRIM31 TRIM21 RNF114 TRIM10 CHFR NFX1 TRIM60

1.20e-0622311510PF00097
DomainZnf_RING_CS

TRIM61 TRIM31 TRIM21 RNF114 TRIM10 CHFR RNF208 TRIM60

7.60e-061631158IPR017907
Domain-

FSTL3 FBN2 LTBP4

1.25e-05811533.90.290.10
DomainLAMININ_IVA

LAMA1 LAMA5 LAMC3

1.25e-0581153PS51115
DomainLaminin_B

LAMA1 LAMA5 LAMC3

1.25e-0581153PF00052
DomainLamB

LAMA1 LAMA5 LAMC3

1.25e-0581153SM00281
DomainLaminin_IV

LAMA1 LAMA5 LAMC3

1.25e-0581153IPR000034
DomainTB_dom

FSTL3 FBN2 LTBP4

1.86e-0591153IPR017878
DomainTB

FSTL3 FBN2 LTBP4

1.86e-0591153PS51364
DomainZnf_RING/FYVE/PHD

BIRC8 RNF168 TRIM61 TRIM31 XIAP SIAH1 TRIM21 RNF114 TRIM10 CHFR RNF208 TRIM60

2.63e-0545911512IPR013083
DomainFol_N

FSTL3 SNED1 SLIT2

3.62e-05111153IPR003645
DomainLaminin_G_1

LAMA1 SLIT2 EYS

3.62e-05111153PF00054
DomainFOLN

FSTL3 SNED1 SLIT2

3.62e-05111153SM00274
DomainKELK

CDC42BPA CDC42BPB

3.76e-0521152IPR031597
DomainKELK

CDC42BPA CDC42BPB

3.76e-0521152PF15796
Domain-

TRIM61 TRIM31 TRIM21 TRIM10 TRIM60

7.64e-057111554.10.45.10
DomainLdl_recept_b

LRP8 LRP1 LRP2

7.88e-05141153PF00058
DomainLDLRB

LRP8 LRP1 LRP2

7.88e-05141153PS51120
DomainCNH

CDC42BPA GARNL3 CDC42BPB

7.88e-05141153SM00036
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

VWF MATN3 LAMA1 LAMA5 LAMB1 LAMC3 ITGA9 FBLN1 SCUBE1 FBN2 PXDN TIMP2 SCUBE3 LTBP4

4.52e-093008814M610
PathwayREACTOME_DEFECTIVE_LFNG_CAUSES_SCDO3

NOTCH1 NOTCH2 NOTCH3 NOTCH4

7.05e-095884M27411
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00382

NFX1 NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.05e-0813885M47534
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_THE_ENDOPLASMIC_RETICULUM

NOTCH1 NOTCH2 NOTCH3 NOTCH4

2.11e-086884M27068
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

SSPOP MUC5AC MUC6 NOTCH1 NOTCH2 NOTCH3 NOTCH4

2.06e-0768887M27303
PathwayPID_A6B1_A6B4_INTEGRIN_PATHWAY

ERBB3 LAMA1 LAMA5 LAMB1 LAMC3 MET

3.82e-0746886M239
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_PROTEOLYTIC_ACTIVATION

NOTCH1 NOTCH2 NOTCH3 NOTCH4

4.52e-0711884M47865
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00380

NOTCH1 NOTCH2 NOTCH3 NOTCH4

6.75e-0712884M47532
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00381

NOTCH1 NOTCH2 NOTCH3 NOTCH4

6.75e-0712884M47533
PathwayKEGG_ECM_RECEPTOR_INTERACTION

LAMB4 VWF LAMA1 LAMA5 LAMB1 LAMC3 ITGA9

8.90e-0784887M7098
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_SIGNALING_PATHWAY

NOTCH1 NOTCH2 NOTCH3 NOTCH4

9.71e-0713884M47423
PathwayREACTOME_MET_ACTIVATES_PTK2_SIGNALING

LAMA1 LAMA5 LAMB1 LAMC3 MET

1.06e-0630885M27772
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI

NOTCH1 NOTCH3 NOTCH4

2.33e-065883MM14733
PathwayREACTOME_DISEASES_OF_GLYCOSYLATION

SSPOP GPC4 MUC5AC MUC6 NOTCH1 NOTCH2 NOTCH3 NOTCH4

2.99e-06143888M27275
PathwayKEGG_FOCAL_ADHESION

LAMB4 VWF LAMA1 LAMA5 LAMB1 XIAP LAMC3 ITGA9 MET

4.05e-06199889M7253
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI

NOTCH1 NOTCH2 NOTCH3 NOTCH4

4.06e-0618884M614
PathwayREACTOME_MET_PROMOTES_CELL_MOTILITY

LAMA1 LAMA5 LAMB1 LAMC3 MET

5.31e-0641885M27778
PathwayREACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING

NOTCH1 NOTCH3 NOTCH4

8.08e-067883MM14734
PathwayKEGG_DORSO_VENTRAL_AXIS_FORMATION

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.37e-0524884M11190
PathwayKEGG_SMALL_CELL_LUNG_CANCER

LAMB4 LAMA1 LAMA5 LAMB1 XIAP LAMC3

1.37e-0584886M3228
PathwayWP_CANONICAL_AND_NONCANONICAL_NOTCH_SIGNALING

NOTCH1 NOTCH2 NOTCH3 NOTCH4

2.23e-0527884M39545
PathwayREACTOME_DISEASES_OF_METABOLISM

CUBN SSPOP GPC4 MUC5AC MUC6 NOTCH1 NOTCH2 NOTCH3 NOTCH4

2.53e-05250889M27554
PathwayREACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY

NOTCH1 NOTCH2 NOTCH3 NOTCH4

2.59e-0528884M6177
PathwayWP_SMALL_CELL_LUNG_CANCER

LAMB4 BIRC8 LAMA1 LAMA5 LAMB1 LAMC3

2.94e-0596886M39834
PathwayPID_NOTCH_PATHWAY

SSPOP NOTCH1 NOTCH2 NOTCH3 NOTCH4

3.25e-0559885M17
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

VWF MATN3 ITGA9 SCUBE1 FBN2 PXDN TIMP2 SCUBE3 LTBP4

3.25e-05258889MM14572
PathwayWP_FOCAL_ADHESION

VWF LAMA1 LAMA5 LAMB1 XIAP LAMC3 ITGA9 MET

3.35e-05199888M39402
PathwayREACTOME_LAMININ_INTERACTIONS

LAMA1 LAMA5 LAMB1 LAMC3

3.43e-0530884M27216
PathwayPID_INTEGRIN4_PATHWAY

LAMA1 LAMA5 LAMB1

3.74e-0511883M158
PathwayWP_OSX_AND_MIRNAS_IN_TOOTH_DEVELOPMENT

NOTCH1 NOTCH2 NOTCH3 NOTCH4

5.70e-0534884M39390
PathwayWP_CANCER_PATHWAYS

LAMB4 LAMA1 LAMA5 LAMB1 XIAP LAMC3 MET PTCH2 NOTCH1 NOTCH2 NOTCH3 NOTCH4

7.02e-055078812M48302
PathwayREACTOME_ECM_PROTEOGLYCANS

MATN3 LAMA1 LAMA5 LAMB1 ITGA9

1.10e-0476885M27219
PathwayREACTOME_SIGNALING_BY_MET

LAMA1 LAMA5 LAMB1 LAMC3 MET

1.32e-0479885M27643
PathwayWP_DELTANOTCH_SIGNALING_PATHWAY

NOTCH1 NOTCH2 NOTCH3 NOTCH4 CCN3

1.58e-0482885MM15922
PathwayWP_FOCAL_ADHESION

VWF LAMA1 LAMA5 LAMB1 LAMC3 ITGA9 MET

1.66e-04187887MM15913
PathwayWP_NOTCH_SIGNALING_WP268

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.74e-0445884M39571
PathwayREACTOME_METABOLISM_OF_FAT_SOLUBLE_VITAMINS

LRP8 GPC4 LRP1 LRP2

1.74e-0445884MM15344
PathwayWP_NOTCH_SIGNALING_PATHWAY

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.89e-0446884MM15971
PathwayKEGG_NOTCH_SIGNALING_PATHWAY

NOTCH1 NOTCH2 NOTCH3 NOTCH4

2.06e-0447884M7946
PathwayREACTOME_METABOLISM_OF_FAT_SOLUBLE_VITAMINS

LRP8 GPC4 LRP1 LRP2

2.24e-0448884M27642
PathwayREACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX

LAMA5 LAMB1 SCUBE1 FBN2 TIMP2 SCUBE3

2.39e-04140886M587
PathwayREACTOME_NOTCH4_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

NOTCH1 NOTCH2 NOTCH4

2.48e-0420883M27881
PathwayREACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY

NOTCH1 NOTCH3 NOTCH4

3.80e-0423883MM14954
PathwayREACTOME_TNFR1_INDUCED_PROAPOPTOTIC_SIGNALING

BIRC8 XIAP TNFRSF1A

3.80e-0423883MM15177
PathwayREACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS

LAMA1 LAMA5 LAMB1 LAMC3

4.97e-0459884M27218
PathwayWP_NOTCH_SIGNALING_WP61

NOTCH1 NOTCH2 NOTCH3 NOTCH4

5.64e-0461884M39540
PathwayREACTOME_SMAC_XIAP_REGULATED_APOPTOTIC_RESPONSE

BIRC8 XIAP

5.69e-046882MM14489
PathwayWP_ALPHA_6_BETA_4_INTEGRIN_SIGNALING_PATHWAY

LAMA1 LAMA5 LAMB1 MET

7.61e-0466884MM15925
PathwayPID_INTEGRIN1_PATHWAY

LAMA1 LAMA5 LAMB1 ITGA9

7.61e-0466884M18
PathwayREACTOME_ACTIVATION_OF_CASPASES_THROUGH_APOPTOSOME_MEDIATED_CLEAVAGE

BIRC8 XIAP

7.93e-047882MM14486
PathwayWP_INFLAMMATORY_RESPONSE_PATHWAY

LAMA5 LAMB1 TNFRSF1A

8.45e-0430883M39641
PathwayWP_INFLAMMATORY_RESPONSE_PATHWAY

LAMA5 LAMB1 TNFRSF1A

8.45e-0430883MM15812
PathwayKEGG_PATHWAYS_IN_CANCER

LAMB4 LAMA1 LAMA5 LAMB1 XIAP LAMC3 MET PTCH2

9.49e-04325888M12868
PathwayREACTOME_RELAXIN_RECEPTORS

RXFP3 RXFP4

1.05e-038882M27371
PathwayWP_ALPHA_6_BETA_4_SIGNALING

LAMA1 LAMA5 LAMB1

1.12e-0333883M39503
PathwayREACTOME_TNFR1_INDUCED_NF_KAPPA_B_SIGNALING_PATHWAY

BIRC8 XIAP TNFRSF1A

1.12e-0333883MM15180
PathwayWP_PI3KAKT_SIGNALING

LAMB4 VWF LAMA1 LAMA5 LAMB1 LAMC3 ITGA9 MET

1.24e-03339888M39736
PathwayKEGG_MEDICUS_REFERENCE_HEDGEHOG_SIGNALING_PATHWAY_PTCH_CORECEPTOR

PTCH2 LRP2

1.35e-039882M47893
PathwayWP_NEOVASCULARIZATION_PROCESSES

NOTCH1 NOTCH3 NOTCH4

1.57e-0337883M39506
PathwayREACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES

FBLN1 FBN2 LTBP4

1.57e-0337883M27134
PathwayREACTOME_REGULATION_OF_COMMISSURAL_AXON_PATHFINDING_BY_SLIT_AND_ROBO

SLIT2 NELL2

1.68e-0310882M27348
PathwayREACTOME_REGULATION_OF_PTEN_LOCALIZATION

BIRC8 XIAP

1.68e-0310882MM15539
PathwayREACTOME_FORMATION_OF_APOPTOSOME

BIRC8 XIAP

1.68e-0310882MM14485
PathwayREACTOME_RELAXIN_RECEPTORS

RXFP3 RXFP4

1.68e-0310882MM15111
PathwayREACTOME_SIGNALING_BY_NOTCH

NOTCH1 NOTCH3 NOTCH4

1.83e-0339883MM14604
PathwayKEGG_MEDICUS_REFERENCE_LOADING_OF_THE_SMC5_SMC6_COMPLEX

RNF168 NSMCE1

2.04e-0311882M47947
PathwayBIOCARTA_PRION_PATHWAY

LAMA1 LAMB1

2.44e-0312882M22020
PathwayBIOCARTA_HES_PATHWAY

NOTCH1 NOTCH2

2.44e-0312882MM1562
PathwayBIOCARTA_HES_PATHWAY

NOTCH1 NOTCH2

2.44e-0312882M22042
PathwayREACTOME_CYTOCHROME_C_MEDIATED_APOPTOTIC_RESPONSE

BIRC8 XIAP

2.44e-0312882MM14487
PathwayREACTOME_VITAMIN_D_CALCIFEROL_METABOLISM

CUBN LRP2

2.44e-0312882M27088
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

FBLN1 FBN2 LTBP4

2.59e-0344883M26969
PathwayREACTOME_VISUAL_PHOTOTRANSDUCTION

LRP8 GPC4 LRP1 LRP2

2.61e-0392884MM14881
PathwayWP_FOCAL_ADHESION_PI3KAKTMTORSIGNALING

VWF LAMA1 LAMA5 LAMB1 LAMC3 ITGA9 MET

2.79e-03302887M39719
PathwayREACTOME_REGULATION_OF_TNFR1_SIGNALING

BIRC8 XIAP TNFRSF1A

3.13e-0347883MM15179
PathwayWP_NEURAL_CREST_DIFFERENTIATION

NOTCH1 NOTCH2 NOTCH3 NOTCH4

3.16e-0397884MM15926
PathwayWP_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_IN_COLORECTAL_CANCER

PKD1 NOTCH1 NOTCH2 NOTCH3 NOTCH4

3.34e-03161885M39770
PathwayWP_EICOSANOID_METABOLISM_VIA_CYTOCHROME_P450_MONOOXYGENASES

CYP2C9 CYP2C18

3.34e-0314882MM15842
PathwayREACTOME_VISUAL_PHOTOTRANSDUCTION

LRP8 GPC4 LRP1 LRP2

3.52e-03100884M27158
PathwayWP_NEURAL_CREST_DIFFERENTIATION

NOTCH1 NOTCH2 NOTCH3 NOTCH4

3.65e-03101884M39448
PathwayREACTOME_SIGNALING_BY_ACTIVIN

FSTL3 ACVR1C

3.84e-0315882MM14593
Pubmed

Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia.

VWF CRIM1 LAMB1 SIAH1 GRN NELL1 FBLN1 NELL2 MEGF8 LRP1 LTBP4 NOTCH1

6.03e-151181151221078624
Pubmed

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.

VWF FSTL3 LAMA1 LAMB1 GRN SLIT2 FBLN1 PXDN TIMP2 GPC4 LTBP4 CCN3 PCSK9

2.31e-122481151324006456
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

FRAS1 FSTL3 CRIM1 LAMA1 LAMA5 LAMB1 LAMC3 GRN LRP8 MET FBLN1 NELL2 HEG1 FBN2 PXDN MEGF8 LRP1 TNFRSF1A NOTCH1 NOTCH2 NOTCH3 CCN3 PCSK9

8.55e-1212011152335696571
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

VWF LAMA1 LAMA5 LAMB1 SSPOP SLIT2 FBN2 PXDN HMCN1 GPC4 LTBP4

1.73e-111751151128071719
Pubmed

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.

ERBB3 INSRR LRP8 LRP1 LRP2 TNFRSF1A NOTCH1 NOTCH2 NOTCH3

5.57e-11101115923382219
Pubmed

Protein interactome reveals converging molecular pathways among autism disorders.

VWF DBF4B LAMA5 GRN SLIT2 NELL1 FBLN1 NELL2 MEGF8 FHL2 LTBP4 NOTCH1 MEGF10 NOTCH2 NOTCH3 CCN3

5.70e-115601151621653829
Pubmed

Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.

SSPOP CRB1 FBN2 TENM4 LRP1 LRP2 MUC5AC MUC6

9.98e-1171115833541421
Pubmed

The 4 Notch receptors play distinct and antagonistic roles in the proliferation and hepatocytic differentiation of liver progenitors.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.13e-104115424145721
Pubmed

A switch in Notch gene expression parallels stem cell to endothelial transition in infantile hemangioma.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.13e-104115420069356
Pubmed

Expression and clinical significance of Notch receptors in human renal cell carcinoma.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.13e-104115419404845
Pubmed

Notch signaling pathway regulates the growth and the expression of inflammatory cytokines in mouse basophils.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.13e-104115428669409
Pubmed

Characterization and developmental expression of the amphioxus homolog of Notch (AmphiNotch): evolutionary conservation of multiple expression domains in amphioxus and vertebrates.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.13e-104115411401408
Pubmed

Functional conservation of mouse Notch receptor family members.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.13e-10411548898100
Pubmed

Notch pathway activity identifies cells with cancer stem cell-like properties and correlates with worse survival in lung adenocarcinoma.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.13e-104115423444212
Pubmed

Deregulated expression of Notch receptors in human hepatocellular carcinoma.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.13e-104115417920003
Pubmed

Prognostic roles of mRNA expression of notch receptors in non-small cell lung cancer.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.13e-104115428061457
Pubmed

Evolutionary analysis of vertebrate Notch genes.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.13e-104115411466531
Pubmed

Abnormal expression pattern of Notch receptors, ligands, and downstream effectors in the dorsolateral prefrontal cortex and amygdala of suicidal victims.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.13e-104115424151014
Pubmed

Notch as a mediator of cell fate determination in hematopoiesis: evidence and speculation.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.13e-104115410194420
Pubmed

Conservation of the biochemical mechanisms of signal transduction among mammalian Notch family members.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.13e-104115411459941
Pubmed

Mutational analysis of NOTCH1, 2, 3 and 4 genes in common solid cancers and acute leukemias.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.13e-104115418184405
Pubmed

Notch signaling in the mammalian central nervous system: insights from mouse mutants.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.13e-104115415917835
Pubmed

Inhibition of notch1-dependent cardiomyogenesis leads to a dilated myopathy in the neonatal heart.

VWF NOTCH1 NOTCH2 NOTCH3 NOTCH4

4.56e-1013115520558824
Pubmed

MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

5.66e-105115411101851
Pubmed

Notch and MAML-1 complexation do not detectably alter the DNA binding specificity of the transcription factor CSL.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

5.66e-105115421124806
Pubmed

Intraovarian regulation of gonadotropin-dependent folliculogenesis depends on notch receptor signaling pathways not involving Delta-like ligand 4 (Dll4).

NOTCH1 NOTCH2 NOTCH3 NOTCH4

5.66e-105115423675950
Pubmed

Functional redundancy of the Notch gene family during mouse embryogenesis: analysis of Notch gene expression in Notch3-deficient mice.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

5.66e-105115415882997
Pubmed

RBP-L, a transcription factor related to RBP-Jkappa.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.69e-09611549111338
Pubmed

Characterization of Notch receptor expression in the developing mammalian heart and liver.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.69e-096115412244553
Pubmed

Interaction with factor inhibiting HIF-1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathways.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.69e-096115418299578
Pubmed

Cloning and functional characterization of the murine mastermind-like 1 (Maml1) gene.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.69e-096115415019995
Pubmed

Notch controls the magnitude of T helper cell responses by promoting cellular longevity.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.69e-096115422615412
Pubmed

Notch signaling is a critical regulator of allogeneic CD4+ T-cell responses mediating graft-versus-host disease.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.69e-096115420870902
Pubmed

Profiling immunohistochemical expression of NOTCH1-3, JAGGED1, cMET, and phospho-MAPK in 100 carcinomas of unknown primary.

MET NOTCH1 NOTCH2 NOTCH3

1.69e-096115422526456
Pubmed

Epidermal growth factor-like domain 7 (EGFL7) modulates Notch signalling and affects neural stem cell renewal.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.69e-096115419503073
Pubmed

Notch lineages and activity in intestinal stem cells determined by a new set of knock-in mice.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.69e-096115421991352
Pubmed

Amplification of extracellular matrix and oncogenes in tat-transfected human salivary gland cell lines with expression of laminin, fibronectin, collagens I, III, IV, c-myc and p53.

LAMB4 LAMA1 LAMA5 LAMB1 LAMC3

3.00e-0918115511311202
Pubmed

Human ligands of the Notch receptor.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

3.94e-097115410079256
Pubmed

The distribution of Notch receptors and their ligands during articular cartilage development.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

3.94e-097115412846471
Pubmed

Murine notch homologs (N1-4) undergo presenilin-dependent proteolysis.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

3.94e-097115411518718
Pubmed

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.

FRAS1 VWF LAMA1 LAMA5 LAMB1 FBLN1 PXDN HMCN1 LTBP4

4.97e-09167115922159717
Pubmed

Distinct expression patterns of notch family receptors and ligands during development of the mammalian inner ear.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

7.86e-09811549858718
Pubmed

Cranial neural crest ablation of Jagged1 recapitulates the craniofacial phenotype of Alagille syndrome patients.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

7.86e-098115422156581
Pubmed

Notch1 and Jagged1 expression by the developing pulmonary vasculature.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

7.86e-098115412242716
Pubmed

Transcriptome-based systematic identification of extracellular matrix proteins.

CRISPLD2 FRAS1 LAMA1 LAMA5 LAMB1 LAMC3 FBLN1

8.56e-0979115718757743
Pubmed

E3 ubiquitin ligase FBXW7 balances airway cell fates.

MUC5AC NOTCH1 NOTCH2 NOTCH3 NOTCH4

9.12e-0922115534998785
Pubmed

Dynamic expression patterns of the pudgy/spondylocostal dysostosis gene Dll3 in the developing nervous system.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.41e-089115411118901
Pubmed

Notch1 signals through Jagged2 to regulate apoptosis in the apical ectodermal ridge of the developing limb bud.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.41e-089115416245338
Pubmed

Identification of a family of mastermind-like transcriptional coactivators for mammalian notch receptors.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.41e-089115412370315
Pubmed

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.

LAMB1 SIAH1 GRN SSPOP NELL1 SETDB1 DZANK1 FBLN1 NELL2 MEGF8 LRP2 FHL2 LTBP4 NOTCH1

1.51e-086081151416713569
Pubmed

Adamts18 modulates the development of the aortic arch and common carotid artery.

LAMA1 LAMA5 LAMB1 FBN2 NOTCH3

2.25e-0826115534189436
Pubmed

Spatiotemporal expression of Notch receptors and ligands in developing mouse placenta.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

2.35e-0810115423665443
Pubmed

Trophoblast-specific expression and function of the integrin alpha 7 subunit in the peri-implantation mouse embryo.

LAMA1 LAMA5 LAMB1 LAMC3

2.35e-0810115411784026
Pubmed

Notch4 signaling limits regulatory T-cell-mediated tissue repair and promotes severe lung inflammation in viral infections.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

2.35e-0810115433915108
Pubmed

Notch signaling prevents mucous metaplasia in mouse conducting airways during postnatal development.

MUC5AC NOTCH1 NOTCH2 NOTCH3 NOTCH4

2.76e-0827115521791528
Pubmed

Genetic link between renal birth defects and congenital heart disease.

FRAS1 LAMA5 SLIT2 PKD1 LRP2

3.35e-0828115527002738
Pubmed

Notch receptor expression in human brain arteriovenous malformations.

NOTCH1 NOTCH3 NOTCH4

3.52e-083115325846406
Pubmed

Complementary and combinatorial patterns of Notch gene family expression during early mouse development.

NOTCH1 NOTCH2 NOTCH3

3.52e-08311538645602
Pubmed

Effect of notch1,2,3 genes silicing on NF-κB signaling pathway of macrophages in patients with atherosclerosis.

NOTCH1 NOTCH2 NOTCH3

3.52e-083115327697639
Pubmed

Differential expression of Notch genes in human osteoblastic cells.

NOTCH1 NOTCH2 NOTCH4

3.52e-083115311836628
Pubmed

Notch signaling: cell fate control and signal integration in development.

NOTCH1 NOTCH2 NOTCH4

3.52e-083115310221902
Pubmed

Expression of Notch 1, 2 and 3 is regulated by epithelial-mesenchymal interactions and retinoic acid in the developing mouse tooth and associated with determination of ameloblast cell fate.

NOTCH1 NOTCH2 NOTCH3

3.52e-08311537615640
Pubmed

The novel Notch homologue mouse Notch 3 lacks specific epidermal growth factor-repeats and is expressed in proliferating neuroepithelium.

NOTCH1 NOTCH2 NOTCH3

3.52e-08311537918097
Pubmed

Expression of Notch1 to -4 and their ligands in renal cell carcinoma: a tissue microarray study.

NOTCH1 NOTCH2 NOTCH3

3.52e-083115321471519
Pubmed

Overlapping but distinct roles for NOTCH receptors in human cardiovascular disease.

NOTCH1 NOTCH2 NOTCH3

3.52e-083115329767458
Pubmed

The human NOTCH1, 2, and 3 genes are located at chromosome positions 9q34, 1p13-p11, and 19p13.2-p13.1 in regions of neoplasia-associated translocation.

NOTCH1 NOTCH2 NOTCH3

3.52e-08311537698746
Pubmed

Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects.

MATN3 LAMA1 DGKE NELL1 THBD PKD1 NOTCH1 NOTCH3 PCSK9

3.63e-08210115916537572
Pubmed

Mutations in LAMB1 cause cobblestone brain malformation without muscular or ocular abnormalities.

LAMA1 LAMA5 LAMB1 LAMC3

3.68e-0811115423472759
Pubmed

A family of mammalian Fringe genes implicated in boundary determination and the Notch pathway.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

3.68e-081111549187150
Pubmed

Jag2-Notch1 signaling regulates oral epithelial differentiation and palate development.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

3.68e-0811115416607638
Pubmed

Coexpression of Cux-1 and Notch signaling pathway components during kidney development.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

3.68e-0811115415499562
Pubmed

Localisation of members of the notch system and the differentiation of vibrissa hair follicles: receptors, ligands, and fringe modulators.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

3.68e-0811115410878608
Pubmed

Regional differences in the expression of laminin isoforms during mouse neural tube development.

LAMA1 LAMA5 LAMB1 LAMC3

3.68e-0811115421524702
Pubmed

Notch-associated gene expression in embryonic and adult taste papillae and taste buds suggests a role in taste cell lineage decisions.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

3.68e-0811115412866128
Pubmed

Notch signaling in stomach epithelial stem cell homeostasis.

MUC5AC NOTCH1 NOTCH2 NOTCH3 NOTCH4

4.04e-0829115521402740
Pubmed

Global genetic analysis in mice unveils central role for cilia in congenital heart disease.

FRAS1 LAMA5 SLIT2 MEGF8 PKD1 LRP1 LRP2

4.46e-08100115725807483
Pubmed

Developmental expression of the Notch signaling pathway genes during mouse preimplantation development.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

5.50e-0812115415465494
Pubmed

Basic helix-loop-helix transcription factors regulate the neuroendocrine differentiation of fetal mouse pulmonary epithelium.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

5.50e-0812115410952889
Pubmed

Systematic analysis of dimeric E3-RING interactions reveals increased combinatorial complexity in human ubiquitination networks.

TRIM31 XIAP SIAH1 TRIM21 RNF114 CHFR RNF208

6.26e-08105115722493164
Pubmed

A regulatory T cell Notch4-GDF15 axis licenses tissue inflammation in asthma.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

7.93e-0813115432929274
Pubmed

Mesangial cells organize the glomerular capillaries by adhering to the G domain of laminin alpha5 in the glomerular basement membrane.

LAMA1 LAMA5 LAMB1 FBLN1

7.93e-0813115412682087
Pubmed

Vascular expression of Notch pathway receptors and ligands is restricted to arterial vessels.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

7.93e-0813115411578869
Pubmed

TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination.

FRAS1 LAMA5 LAMB1 GRN MET TENM4 PXDN LRP1

7.94e-08164115832409323
Pubmed

Functional proteomics mapping of a human signaling pathway.

VWF RNF168 LAMA5 SIAH1 GRN SETDB1 FBLN1 FBN2 PKD1 LRP1 HERC1 FHL2 NOTCH2

8.68e-085911151315231748
Pubmed

Defining brain wiring patterns and mechanisms through gene trapping in mice.

CRIM1 LAMA1 LAMB1 NOTCH3

1.11e-0714115411242070
Pubmed

Cell-fate transition and determination analysis of mouse male germ cells throughout development.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.11e-0714115434824237
Pubmed

Math1 controls cerebellar granule cell differentiation by regulating multiple components of the Notch signaling pathway.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.11e-0714115414757642
Pubmed

Expression of laminin chains by central neurons: analysis with gene and protein trapping techniques.

LAMA1 LAMA5 LAMB1

1.41e-074115312820173
Pubmed

Mouse jagged1 physically interacts with notch2 and other notch receptors. Assessment by quantitative methods.

NOTCH1 NOTCH2 NOTCH3

1.41e-074115310551863
Pubmed

Notch signalling is linked to epidermal cell differentiation level in basal cell carcinoma, psoriasis and wound healing.

NOTCH1 NOTCH2 NOTCH3

1.41e-074115311978185
Pubmed

Laminin-1 reexpression in Alport mouse glomerular basement membranes.

LAMA1 LAMA5 LAMB1

1.41e-074115312631063
Pubmed

Developmental regulation of the laminin alpha5 chain suggests a role in epithelial and endothelial cell maturation.

LAMA1 LAMA5 LAMB1

1.41e-07411539299121
Pubmed

Novel MIR143-NOTCH fusions in benign and malignant glomus tumors.

NOTCH1 NOTCH2 NOTCH3

1.41e-074115323999936
Pubmed

NOTCH1 regulates osteoclastogenesis directly in osteoclast precursors and indirectly via osteoblast lineage cells.

NOTCH1 NOTCH2 NOTCH3

1.41e-074115318156632
Pubmed

Expression of Notch pathway genes in the embryonic mouse metanephros suggests a role in proximal tubule development.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.51e-0715115412971992
Pubmed

Basement membrane composition in the early mouse embryo day 7.

LAMA1 LAMA5 LAMB1 LAMC3

1.51e-0715115415895400
Pubmed

Mouse Fbw7/Sel-10/Cdc4 is required for notch degradation during vascular development.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.51e-0715115414672936
Pubmed

Expression of Notch pathway components in fetal and adult mouse small intestine.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

2.00e-0716115412617809
Pubmed

An essential role for Notch in neural crest during cardiovascular development and smooth muscle differentiation.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

2.00e-0716115417273555
Pubmed

Requirement of Math1 for secretory cell lineage commitment in the mouse intestine.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

2.00e-0716115411739954
InteractionIGFL3 interactions

FRAS1 LAMA1 LAMA5 LAMB1 GRN FBLN1 FBN2 PXDN LRP2 NOTCH1 NOTCH2 NOTCH3

1.15e-147511412int:IGFL3
InteractionZFP41 interactions

FRAS1 GRN FBLN1 NELL2 FBN2 LRP1 LRP2 LTBP4 NOTCH2 NOTCH3

7.75e-135711410int:ZFP41
InteractionFBXO2 interactions

FRAS1 LAMA1 LAMA5 LAMB1 LAMC3 GRN SNED1 SLIT2 MET NELL2 FBN2 PXDN MEGF8 LRP2 LTBP4 NOTCH1 NOTCH2 NOTCH3

1.72e-1141111418int:FBXO2
InteractionNTN5 interactions

FRAS1 FBN2 LRP2 LTBP4 NOTCH1 NOTCH2 NOTCH3

4.92e-11241147int:NTN5
InteractionCACNA1A interactions

VWF CRIM1 LAMB1 GRN NELL1 FBLN1 NELL2 MEGF8 LRP1 LTBP4 NOTCH1

1.05e-1012311411int:CACNA1A
InteractionHOXA1 interactions

SPRY3 VWF DBF4B LAMA5 GRN SLIT2 NELL1 FBLN1 NELL2 MEGF8 KRTAP1-5 LTBP4 NOTCH1 RNF208 NOTCH3 CCN3

1.73e-1035611416int:HOXA1
InteractionSLURP1 interactions

LAMA5 LAMB1 GRN MET FBLN1 NELL2 PXDN MEGF8 TIMP2 NOTCH2

9.15e-0914411410int:SLURP1
InteractionZNF408 interactions

FRAS1 LAMA1 GRN NELL2 FBN2 LRP2 FHL2 LTBP4 NOTCH2 NOTCH3

9.78e-0914511410int:ZNF408
InteractionATXN7 interactions

VWF CRIM1 LAMB1 SIAH1 GRN NELL1 NELL2 MEGF8 LTBP4

1.14e-081091149int:ATXN7
InteractionEGFL7 interactions

GRN NELL1 NELL2 PROZ NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.24e-08771148int:EGFL7
InteractionMFAP5 interactions

VWF LAMA5 GRN FBLN1 FBN2 LTBP4 NOTCH3

1.67e-08521147int:MFAP5
InteractionMAML3 interactions

NFX1 NOTCH1 NOTCH2 NOTCH3 NOTCH4

7.68e-08201145int:MAML3
InteractionGFI1B interactions

LAMB1 GRN NELL1 DZANK1 FBLN1 NELL2 MEGF8 LTBP4 NOTCH1

7.92e-081361149int:GFI1B
InteractionATN1 interactions

SIAH1 GRN SSPOP LYST NELL1 FBLN1 NELL2 MEGF8 LRP2 LTBP4

1.10e-0718711410int:ATN1
InteractionMBD1 interactions

GRN NELL1 SETDB1 NELL2 LTBP4 NOTCH1 NOTCH3

2.67e-07771147int:MBD1
InteractionLGALS1 interactions

FRAS1 LAMA5 LAMB1 GRN ITGA9 MET HEG1 TIMP2 LRP2 NOTCH1 NOTCH2 NOTCH3

4.03e-0733211412int:LGALS1
InteractionZDHHC15 interactions

SSPOP CRB1 FBN2 TENM4 LRP1 LRP2 MUC5AC MUC6

5.55e-071251148int:ZDHHC15
InteractionPRG2 interactions

FRAS1 LAMA5 LAMC3 FBN2 PXDN TIMP2 LTBP4 NOTCH1 NOTCH2 NOTCH3 PCSK9

6.61e-0728511411int:PRG2
InteractionADAMTSL1 interactions

GRN FBN2 TIMP2 FHL2

6.68e-07131144int:ADAMTSL1
InteractionELSPBP1 interactions

LAMA5 FBLN1 MEGF8 TIMP2 NOTCH1 NOTCH2 PCSK9

9.07e-07921147int:ELSPBP1
InteractionDEFA1 interactions

LAMA5 LAMB1 GRN SLIT2 FBLN1 PXDN NOTCH3

1.60e-061001147int:DEFA1
InteractionNICOL1 interactions

NELL1 NELL2 TIMP2

1.75e-0651143int:NICOL1
InteractionUBE2D2 interactions

BIRC8 RNF168 TRIM31 XIAP SIAH1 TRIM21 RNF114 TRIM10 CHFR HERC1 NSMCE1

1.93e-0631811411int:UBE2D2
InteractionMAML2 interactions

NOTCH1 NOTCH2 NOTCH3 NOTCH4

2.18e-06171144int:MAML2
InteractionST14 interactions

CRIM1 LAMB1 SLIT2 MET FBLN1 FBN2 GPC4 NOTCH2 NOTCH3

2.73e-062071149int:ST14
InteractionCCN2 interactions

FBLN1 TIMP2 LRP1 LRP2 CCN3

2.98e-06401145int:CCN2
InteractionNELL1 interactions

NELL1 FBLN1 NELL2 PXDN LTBP4

3.82e-06421145int:NELL1
InteractionUBE2D3 interactions

BIRC8 RNF168 TRIM31 XIAP SIAH1 TRIM21 RNF114 TRIM10 CHFR HERC1

4.79e-0628311410int:UBE2D3
InteractionC1orf54 interactions

LAMA1 LAMA5 LAMB1 MET PXDN PKD1 GPC4 PCSK9

4.91e-061671148int:C1orf54
InteractionUBE2D4 interactions

BIRC8 TRIM31 XIAP SIAH1 RNF114 TRIM10 CHFR

5.12e-061191147int:UBE2D4
InteractionZNF707 interactions

FRAS1 FBLN1 LTBP4 NOTCH1 NOTCH2 NOTCH3

5.70e-06791146int:ZNF707
InteractionCFC1 interactions

FRAS1 LAMA5 LAMB1 MEGF8 LTBP4 NOTCH1 NOTCH2

7.47e-061261147int:CFC1
InteractionPRG3 interactions

FRAS1 SLIT2 FBN2 NOTCH2 PCSK9

8.29e-06491145int:PRG3
InteractionFBLN1 interactions

NELL1 FBLN1 TIMP2 LTBP4 NOTCH2 NOTCH3 CCN3

8.72e-061291147int:FBLN1
InteractionUBE2W interactions

BIRC8 TRIM31 XIAP TRIM21 RNF114 CHFR

1.76e-05961146int:UBE2W
InteractionUBE2E2 interactions

RNF168 TRIM31 XIAP SIAH1 RNF114 CHFR

1.76e-05961146int:UBE2E2
InteractionZNF517 interactions

GRN FBLN1 LRP2 LTBP4

2.07e-05291144int:ZNF517
InteractionHRG interactions

GRN TRIM21 FBN2 TNFRSF1A LTBP4

2.87e-05631145int:HRG
InteractionDAB1 interactions

ERBB3 SIAH1 LRP8 LRP1 LRP2 NOTCH1

3.26e-051071146int:DAB1
InteractionLTBP4 interactions

NELL1 FBLN1 NELL2 LTBP4 NOTCH2

3.87e-05671145int:LTBP4
InteractionC1QTNF7 interactions

LAMA1 LAMA5 SLIT2 FBLN1 PXDN

4.47e-05691145int:C1QTNF7
InteractionUBE2D1 interactions

BIRC8 RNF168 TRIM31 XIAP SIAH1 TRIM21 RNF114 TRIM10 CHFR

4.50e-052941149int:UBE2D1
InteractionIGSF5 interactions

NOTCH1 NOTCH2 NOTCH3

6.13e-05141143int:IGSF5
InteractionAGRP interactions

GRN FBLN1 NOTCH2

6.13e-05141143int:AGRP
InteractionDLL1 interactions

NOTCH1 NOTCH2 NOTCH3 CCN3

6.18e-05381144int:DLL1
InteractionCUBN interactions

CUBN LRP1 LRP2

7.63e-05151143int:CUBN
InteractionSDF2L1 interactions

FRAS1 LAMA5 LAMB1 LAMC3 MET PROZ PXDN MEGF8 PCSK9

9.05e-053221149int:SDF2L1
InteractionSCN3A interactions

LRP8 LRP1 LRP2

9.36e-05161143int:SCN3A
InteractionFGF4 interactions

LAMA1 LAMA5 GRN GPC4

1.11e-04441144int:FGF4
InteractionCD96 interactions

LAMB1 TMEM260 PXDN

1.13e-04171143int:CD96
InteractionLCE1A interactions

SPRY3 GRN FBLN1 KRTAP1-5 CCN3

1.15e-04841145int:LCE1A
InteractionPXDN interactions

NELL1 NELL2 PXDN RNF208 NOTCH2

1.15e-04841145int:PXDN
InteractionPSEN2 interactions

FHL2 NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.28e-04861145int:PSEN2
InteractionNUFIP2 interactions

VWF TRIM31 GRN NELL1 FBLN1 NELL2 KRTAP1-5 FHL2 LTBP4 NOTCH3

1.30e-0441711410int:NUFIP2
InteractionLGALS7 interactions

LAMA1 LAMB1 TRIM21 HEG1 TIMP2 PKD1

1.40e-041391146int:LGALS7
InteractionNOTCH2 interactions

GRN SLIT2 FBLN1 FBN2 PXDN LTBP4 NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.46e-0442311410int:NOTCH2
InteractionTIMP3 interactions

FRAS1 NELL1 TIMP2 LRP2 NOTCH2

1.59e-04901145int:TIMP3
InteractionCCN6 interactions

FRAS1 NOTCH1 NOTCH2

1.60e-04191143int:CCN6
InteractionFRAT1 interactions

LAMC3 GRN LTBP4

1.60e-04191143int:FRAT1
InteractionWNT3A interactions

TIMP2 LRP1 NOTCH1 NOTCH2

1.69e-04491144int:WNT3A
InteractionFOXD4L6 interactions

FBN2 LTBP4 NOTCH1 NOTCH2

1.69e-04491144int:FOXD4L6
InteractionLTBP1 interactions

NELL2 FBN2 TIMP2 NOTCH2 NOTCH3

1.76e-04921145int:LTBP1
InteractionDEFB125 interactions

FBLN1 FBN2 LRP2

1.87e-04201143int:DEFB125
InteractionZNF224 interactions

FBN2 LRP2 NOTCH3

1.87e-04201143int:ZNF224
InteractionRLN3 interactions

RXFP3 RXFP4

1.89e-0441142int:RLN3
InteractionUBE2L3 interactions

RNF168 TRIM31 XIAP TRIM21 RNF114 HECTD2 HERC1

1.99e-042111147int:UBE2L3
InteractionFBXO6 interactions

FRAS1 LAMA5 LAMB1 GRN TRIM21 MET FBLN1 FBN2 TENM4 PXDN MEGF8 LRP1 LTBP4

2.09e-0471711413int:FBXO6
InteractionC19orf33 interactions

XIAP TIMP2 FHL2

2.18e-04211143int:C19orf33
InteractionNOTCH4 interactions

NOTCH2 NOTCH3 NOTCH4

2.18e-04211143int:NOTCH4
InteractionNELL2 interactions

NELL1 NELL2 PXDN LTBP4

2.30e-04531144int:NELL2
InteractionTYW3 interactions

NELL1 FBLN1 NELL2 PROZ

2.30e-04531144int:TYW3
InteractionLY86 interactions

LAMA5 LAMB1 LAMC3 MET FBLN1 TIMP2 PCSK9

2.37e-042171147int:LY86
InteractionPSG3 interactions

LAMB1 FBLN1 MEGF8

2.51e-04221143int:PSG3
InteractionCASR interactions

NOTCH1 NOTCH2 NOTCH3

2.51e-04221143int:CASR
InteractionSCUBE1 interactions

SCUBE1 SCUBE3

3.14e-0451142int:SCUBE1
InteractionCYP2C19 interactions

CYP2C9 CYP2C18

3.14e-0451142int:CYP2C19
InteractionLYPD1 interactions

FRAS1 LAMB1 MEGF8 NOTCH2

3.26e-04581144int:LYPD1
InteractionPDIA4 interactions

ERBB3 VWF RNF168 LAMB1 GRN TRIM21 MET FBN2 LRP2 PCSK9

3.27e-0446811410int:PDIA4
InteractionUBE2E1 interactions

BIRC8 RNF168 XIAP TRIM21 RNF114 CHFR

3.42e-041641146int:UBE2E1
InteractionEDN3 interactions

LAMA5 MEGF8 NOTCH1 NOTCH2 PCSK9

3.72e-041081145int:EDN3
InteractionDTX3 interactions

XIAP TRIM21 RNF114 CHFR NOTCH2

3.72e-041081145int:DTX3
InteractionPLAT interactions

LAMA1 TIMP2 LRP1 NOTCH2

4.47e-04631144int:PLAT
InteractionMATN2 interactions

NELL1 NELL2 FBN2 PXDN SCUBE3

4.58e-041131145int:MATN2
InteractionNOTCH3 interactions

FBLN1 NOTCH1 NOTCH2 NOTCH3 NOTCH4

4.58e-041131145int:NOTCH3
InteractionEMILIN2 interactions

NELL1 NELL2 NOTCH2

4.67e-04271143int:EMILIN2
InteractionCYP2C18 interactions

CYP2C9 CYP2C18 TMEM260

4.67e-04271143int:CYP2C18
InteractionGGH interactions

FRAS1 LAMA5 LAMB1 PXDN MEGF8 TIMP2 PCSK9

4.68e-042431147int:GGH
InteractionADAMTS9 interactions

TRIM21 NOTCH2

4.69e-0461142int:ADAMTS9
InteractionDLL4 interactions

NOTCH1 NOTCH4

4.69e-0461142int:DLL4
InteractionPTPRK interactions

FRAS1 LAMA5 LAMB1 FBLN1 PXDN MEGF8

5.14e-041771146int:PTPRK
InteractionCRIPTO interactions

ACVR1C FBLN1 MEGF8 PCSK9

6.33e-04691144int:CRIPTO
InteractionVXN interactions

TRIM61 FHL2

6.54e-0471142int:VXN
InteractionNLK interactions

TRPS1 GRN TRIM21 NOTCH1

6.68e-04701144int:NLK
InteractionMARCHF1 interactions

MET NOTCH1 NOTCH2 NOTCH3

6.68e-04701144int:MARCHF1
InteractionIL5RA interactions

FRAS1 LAMA5 PXDN MEGF8 PCSK9

6.99e-041241145int:IL5RA
InteractionLCE3D interactions

SPRY3 TENM4 KRTAP1-5 CCN3

7.83e-04731144int:LCE3D
InteractionMAML1 interactions

NOTCH1 NOTCH2 NOTCH3 NOTCH4

7.83e-04731144int:MAML1
InteractionF2 interactions

TRIM31 THBD PROZ TIMP2

8.24e-04741144int:F2
InteractionMSTN interactions

FSTL3 MEGF8 PCSK9

8.50e-04331143int:MSTN
InteractionITGB1BP1 interactions

LRP8 LRP1 LRP2

8.50e-04331143int:ITGB1BP1
CytobandEnsembl 112 genes in cytogenetic band chr7q31

TSPAN12 LAMB4 LAMB1 MET

4.41e-041401154chr7q31
Cytoband7q31

LAMB4 MET

2.10e-032711527q31
Cytoband1p32

NFYC C8B

2.10e-032711521p32
Cytoband9q34.3

MAMDC4 NOTCH1 RNF208

2.45e-0310611539q34.3
Cytoband4q32.3

TRIM61 TRIM60

3.31e-033411524q32.3
Cytoband11p15.5

TRIM21 MUC5AC MUC6

3.31e-03118115311p15.5
Cytoband10q24

CYP2C9 CYP2C18

3.51e-0335115210q24
Cytoband6p21.3

TRIM31 TRIM10 SCUBE3 NOTCH4

3.70e-0325011546p21.3
GeneFamilyLaminin subunits

LAMB4 LAMA1 LAMA5 LAMB1 LAMC3

1.31e-0912825626
GeneFamilyRing finger proteins

RNF168 TRIM61 TRIM31 TRIM21 RNF114 TRIM10 CHFR RNF208 TRIM60

4.25e-0627582958
GeneFamilyLow density lipoprotein receptors

LRP8 LRP1 LRP2

2.49e-0513823634
GeneFamilyRing finger proteins|Tripartite motif containing|ARF GTPase family

TRIM61 TRIM31 TRIM21 TRIM10 TRIM60

7.14e-059582559
GeneFamilyRelaxin family peptide receptors

RXFP3 RXFP4

1.21e-044822217
GeneFamilyRing finger proteins|Baculoviral IAP repeat containing|Caspase recruitment domain containing

BIRC8 XIAP

5.59e-048822419
GeneFamilyFibulins

FBLN1 HMCN1

5.59e-048822556
GeneFamilyCD molecules|Mucins

MUC5AC MUC6

4.03e-0321822648
GeneFamilyAnkyrin repeat domain containing

DZANK1 NOTCH1 NOTCH2 NOTCH3 NOTCH4

4.87e-03242825403
GeneFamilyCD molecules|Tumor necrosis factor receptor superfamily|Death inducing signaling complex

TNFRSF13B TNFRSF1A

7.62e-0329822782
CoexpressionNABA_ECM_GLYCOPROTEINS

CRISPLD2 LAMB4 FRAS1 VWF CRIM1 MATN3 LAMA1 LAMA5 LAMB1 LAMC3 SSPOP SNED1 SLIT2 NELL1 FBLN1 NELL2 EYS FBN2 PXDN HMCN1 USH2A LTBP4 CCN3 OTOG

4.26e-2819611524M3008
CoexpressionNABA_CORE_MATRISOME

CRISPLD2 LAMB4 FRAS1 VWF CRIM1 MATN3 LAMA1 LAMA5 LAMB1 LAMC3 SSPOP SNED1 SLIT2 NELL1 FBLN1 NELL2 EYS FBN2 PXDN HMCN1 USH2A LTBP4 CCN3 OTOG

1.71e-2427511524M5884
CoexpressionNABA_ECM_GLYCOPROTEINS

CRISPLD2 FRAS1 VWF CRIM1 MATN3 LAMA1 LAMA5 LAMB1 LAMC3 SSPOP SNED1 SLIT2 NELL1 FBLN1 NELL2 FBN2 PXDN HMCN1 LTBP4 CCN3 OTOG

1.23e-2319111521MM17059
CoexpressionNABA_MATRISOME

CRISPLD2 LAMB4 FRAS1 VWF FSTL3 CRIM1 MATN3 LAMA1 LAMA5 LAMB1 LAMC3 SSPOP SNED1 SLIT2 NELL1 FBLN1 NELL2 EYS SCUBE1 FBN2 PXDN HMCN1 MEGF8 TIMP2 GPC4 SCUBE3 USH2A LTBP4 MUC5AC MUC6 MEGF10 CCN3 IL9 OTOG

6.81e-21102611534M5889
CoexpressionNABA_CORE_MATRISOME

CRISPLD2 FRAS1 VWF CRIM1 MATN3 LAMA1 LAMA5 LAMB1 LAMC3 SSPOP SNED1 SLIT2 NELL1 FBLN1 NELL2 FBN2 PXDN HMCN1 LTBP4 CCN3 OTOG

1.89e-2027011521MM17057
CoexpressionNABA_MATRISOME

CRISPLD2 FRAS1 VWF FSTL3 CRIM1 MATN3 LAMA1 LAMA5 LAMB1 LAMC3 SSPOP SNED1 SLIT2 NELL1 FBLN1 NELL2 SCUBE1 FBN2 PXDN HMCN1 MEGF8 TIMP2 GPC4 SCUBE3 LTBP4 MUC5AC MUC6 MEGF10 CCN3 IL9 OTOG

4.24e-18100811531MM17056
CoexpressionNABA_BASEMENT_MEMBRANES

LAMB4 LAMA1 LAMA5 LAMB1 LAMC3 HMCN1 USH2A

4.30e-10401157M5887
CoexpressionHU_FETAL_RETINA_FIBROBLAST

LAMA1 LAMB1 LAMC3 SNED1 FBLN1 SCUBE1 FBN2 PXDN HMCN1 GPC4 LTBP4 NOTCH2 NOTCH3

1.53e-0838511513M39264
CoexpressionGAO_LARGE_INTESTINE_ADULT_CJ_IMMUNE_CELLS

CRISPLD2 VWF LAMA5 LAMC3 SNED1 THBD FBLN1 HEG1 PXDN TIMP2 LRP1 PTCH2 NOTCH3 NOTCH4

4.89e-0850511514M39167
CoexpressionMEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3

TSPAN12 CRISPLD2 ERBB3 LAMA1 LAMB1 LAMC3 ITGA9 SNED1 NELL1 THBD SCUBE1 TENM4 HMCN1 PTCH2 SCUBE3 LRP2 CORIN NOTCH1 CCN3

2.16e-07107411519M1941
CoexpressionFUKUSHIMA_TNFSF11_TARGETS

NOTCH1 NOTCH2 NOTCH3 NOTCH4

6.14e-07161154MM1296
CoexpressionFUKUSHIMA_TNFSF11_TARGETS

NOTCH1 NOTCH2 NOTCH3 NOTCH4

6.14e-07161154M2207
CoexpressionAIZARANI_LIVER_C21_STELLATE_CELLS_1

CRISPLD2 LAMB1 LAMC3 ITGA9 FBLN1 TIMP2 LRP1 LTBP4

2.34e-061941158M39122
CoexpressionHALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION

FSTL3 MATN3 LAMA1 SLIT2 FBLN1 FBN2 LRP1 NOTCH2

2.94e-062001158M5930
CoexpressionMIKKELSEN_MCV6_HCP_WITH_H3K27ME3

INSRR GSX2 LAMC3 SLITRK3 SLIT2 NELL1 NELL2 SCUBE1 TIMP2 CCN3

2.40e-0543811510M1954
CoexpressionFRASOR_RESPONSE_TO_ESTRADIOL_DN

ERBB3 LAMB1 SLIT2 NELL2 PXDN

2.44e-05781155M3002
CoexpressionMIKKELSEN_MCV6_HCP_WITH_H3K27ME3

INSRR GSX2 LAMC3 SLITRK3 SLIT2 NELL1 NELL2 SCUBE1 TIMP2 CCN3

2.49e-0544011510MM832
CoexpressionGSE15930_NAIVE_VS_72H_IN_VITRO_STIM_IL12_CD8_TCELL_UP

SIAH1 SLC25A51 TIMP2 PKD1 NFYC ULK2 NOTCH3

2.96e-052001157M3608
CoexpressionNAKAYA_PLASMACYTOID_DENDRITIC_CELL_FLUMIST_AGE_18_50YO_7DY_DN

CYP2C9 CYP2C18 TRIM31 LAMB1 XIAP LYST CRB1 FBLN1 HEG1 MEGF8 CHFR LRP1 LTBP4 NOTCH3

4.55e-0590911514M41018
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HRGL3

CRIM1 SSPOP CRB1 SLIT2 TIMP2 GPC4 LRP1 LRP2 CORIN TNFRSF1A NOTCH2

4.60e-0557411511M39056
CoexpressionMURARO_PANCREAS_MESENCHYMAL_STROMAL_CELL

CRISPLD2 RNF168 LAMB1 LAMC3 HEG1 PXDN HMCN1 TIMP2 FHL2 NOTCH1 NOTCH2 NOTCH3

4.62e-0568111512M39175
CoexpressionNAKAYA_B_CELL_FLUARIX_FLUVIRIN_AGE_18_50YO_7DY_DN

ZDHHC14 LAMA5 CUBN LYST SNED1 NFYC SCUBE3 HERC1

4.77e-052941158M41112
CoexpressionAIZARANI_LIVER_C20_LSECS_3

CRIM1 SLCO4A1 ITGA9 CDC42BPB THBD PXDN HERC1 NOTCH4

4.89e-052951158M39121
CoexpressionDUTERTRE_ESTRADIOL_RESPONSE_24HR_DN

TSPAN12 CRISPLD2 FRAS1 CDC42BPA CRIM1 LAMB1 LYST SLIT2 FBN2 FHL2

7.77e-0550411510M2157
CoexpressionMOHANKUMAR_HOXA1_TARGETS_DN

MATN3 SLITRK3 NELL2 PTCH2 USH2A MUC5AC

1.29e-041761156M9032
CoexpressionNABA_MATRISOME_PRIMARY_METASTATIC_COLORECTAL_TUMOR

PXDN HMCN1 MEGF8 GPC4

1.33e-04591154M47989
CoexpressionDAVICIONI_MOLECULAR_ARMS_VS_ERMS_DN

TRPS1 FBLN1 FBN2 GPC4 TNFRSF1A LTBP4

1.42e-041791156M8519
CoexpressionFAN_EMBRYONIC_CTX_BRAIN_ENDOTHELIAL_1

VWF LAMA5 LAMB1 LRP8 HEG1 PXDN HMCN1 NOTCH1 NOTCH4

1.43e-044401159M39039
CoexpressionTRAVAGLINI_LUNG_PERICYTE_CELL

MATN3 LAMB1 LAMC3 GPC4 NOTCH3

1.49e-041141155M41678
CoexpressionCUI_DEVELOPING_HEART_C3_FIBROBLAST_LIKE_CELL

LAMB1 FBLN1 TIMP2 LRP1 LTBP4

1.69e-041171155M39300
CoexpressionHE_LIM_SUN_FETAL_LUNG_C3_OMD_POS_ENDOTHELIAL_CELL

GARNL3 CRIM1 CUBN MET FBLN1 FBN2 HMCN1 LTBP4

1.76e-043551158M45758
CoexpressionIL2_UP.V1_UP

SLCO4A1 CNKSR2 ITGA9 LRP8 HEG1 USH2A

1.96e-041901156M2822
CoexpressionCHICAS_RB1_TARGETS_CONFLUENT

FBLN1 HEG1 FBN2 TENM4 TIMP2 KRTAP1-5 SCUBE3 CORIN FHL2 NOTCH2

2.03e-0456711510M2129
CoexpressionCUI_DEVELOPING_HEART_VASCULAR_ENDOTHELIAL_CELL

CRIM1 GRN MET THBD HEG1 LTBP4

2.13e-041931156M39321
CoexpressionAIZARANI_LIVER_C32_MVECS_3

VWF FSTL3 CRIM1 THBD HEG1

2.30e-041251155M39131
CoexpressionKRAS.600_UP.V1_DN

FRAS1 CYP2C18 DBF4B SLC5A2 THBD TNFRSF13B MUC5AC

2.36e-042791157M2880
CoexpressionGSE22886_NAIVE_CD8_TCELL_VS_NKCELL_DN

CRIM1 LYST HEG1 TNFRSF1A NOTCH1 NOTCH2

2.38e-041971156M4421
CoexpressionAIZARANI_LIVER_C33_STELLATE_CELLS_2

CRISPLD2 CDC42BPA LAMB1 PXDN NOTCH3

2.38e-041261155M39132
CoexpressionGSE3982_EOSINOPHIL_VS_BCELL_UP

FRAS1 TNFRSF1A MUC5AC NOTCH1 NOTCH2 CCN3

2.52e-041991156M5406
CoexpressionNABA_MATRISOME_METASTATIC_COLORECTAL_LIVER_METASTASIS

PXDN HMCN1 GPC4

3.06e-04301153M47990
CoexpressionKARLSSON_TGFB1_TARGETS_DN

BIRC8 LAMA5 XIAP GRN MET TIMP2

3.27e-042091156MM1058
CoexpressionDESCARTES_FETAL_THYMUS_STROMAL_CELLS

FBLN1 FBN2 LRP1 LTBP4 CCN3

3.51e-041371155M40313
CoexpressionHALLMARK_COAGULATION

VWF THBD PROZ LRP1 C8B

3.63e-041381155M5946
CoexpressionHALLMARK_NOTCH_SIGNALING

NOTCH1 NOTCH2 NOTCH3

3.72e-04321153M5903
CoexpressionFAN_EMBRYONIC_CTX_BRAIN_ENDOTHELIAL_2

TSPAN12 CDC42BPA LAMB1 LAMC3 FBLN1 PXDN NOTCH3

3.89e-043031157M39040
CoexpressionAIZARANI_LIVER_C9_LSECS_1

CRIM1 ITGA9 CDC42BPB PXDN TIMP2 HERC1 NOTCH4

3.97e-043041157M39113
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#4_top-relative-expression-ranked_500

TSPAN12 TRPS1 LAMA1 ACVR1C ITGA9 SLIT2 SCUBE1 FBN2 TENM4 HMCN1 LRP1

1.41e-0820711311gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k4_500
CoexpressionAtlasStromal Cells, St.31-38-44-.SLN, CD45- gp38- CD31- CD44-, Lymph Node, avg-2

TSPAN12 CRISPLD2 CRIM1 LAMA5 LAMB1 ITGA9 THBD PXDN TIMP2 GPC4 LRP1 FHL2 LTBP4 NOTCH3 CCN3

1.84e-0845311315GSM777067_500
CoexpressionAtlaskidney_P4_CapMesRenVes_Crym_k-means-cluster#3_top-relative-expression-ranked_500

FRAS1 TRPS1 LAMA1 LAMB1 CNKSR2 SLIT2 FBN2 TENM4 SCUBE3 NOTCH1

1.91e-0816511310gudmap_kidney_P4_CapMesRenVes_Crym_k3_500
CoexpressionAtlaskidney_P4_CapMesRenVes_Crym_top-relative-expression-ranked_500

FRAS1 CRIM1 TRPS1 LAMA1 LAMB1 CNKSR2 SLIT2 MET FBN2 TENM4 SCUBE3 LRP2 NOTCH1 NOTCH2

2.68e-0839811314gudmap_kidney_P4_CapMesRenVes_Crym_500
CoexpressionAtlasdev gonad_e12.5_F_VasAssMesen_MafB_k-means-cluster#4_top-relative-expression-ranked_500

TSPAN12 TRPS1 LAMA1 SLIT2 SCUBE1 FBN2 TENM4 HMCN1 LRP1

8.72e-081461139gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_k4_500
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#1_top-relative-expression-ranked_1000

LAMA1 ACVR1C ITGA9 TMEM260 SLIT2 THBD FBLN1 FBN2 TENM4 HMCN1 LRP1 LTBP4

1.01e-0731011312gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k1_1000
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_1000

TRPS1 LAMA1 LAMB1 ACVR1C ITGA9 TMEM260 SLIT2 THBD FBLN1 SCUBE1 FBN2 TENM4 PXDN HMCN1 GPC4 LRP1 LTBP4 NOTCH2

1.24e-0776811318gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_1000
CoexpressionAtlaskidney_P4_CapMesRenVes_Crym_top-relative-expression-ranked_1000

FRAS1 CRIM1 TRPS1 LAMA1 LAMA5 LAMB1 CNKSR2 SLIT2 MET FBLN1 NELL2 FBN2 TENM4 SCUBE3 LRP2 CORIN NOTCH1 NOTCH2

1.65e-0778311318gudmap_kidney_P4_CapMesRenVes_Crym_1000
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#2_top-relative-expression-ranked_1000

TRPS1 LAMA1 ITGA9 SLIT2 SCUBE1 HEG1 FBN2 TENM4 HMCN1 LRP1 LTBP4

1.76e-0726511311gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k2_1000
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#1_top-relative-expression-ranked_1000

TSPAN12 TRPS1 LAMA1 ACVR1C ITGA9 SLIT2 FBLN1 SCUBE1 FBN2 TENM4 HMCN1 LRP1

2.47e-0733711312gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k1_1000
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#2_top-relative-expression-ranked_500

LAMA1 ACVR1C ITGA9 SLIT2 THBD TENM4 HMCN1 LRP1 LTBP4

2.48e-071651139gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k2_500
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_500

TRPS1 LAMA1 ACVR1C ITGA9 SLIT2 THBD SCUBE1 TENM4 HMCN1 LRP1 LTBP4 NOTCH2

5.62e-0736411312gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_500
CoexpressionAtlasStromal Cells, LEC.MLN, gp38+ CD31+, Lymph Node, avg-4

TSPAN12 CDC42BPA CRIM1 LAMB1 ITGA9 CDC42BPB SLIT2 MET THBD PXDN HMCN1 TIMP2 LTBP4

6.22e-0743911313GSM777059_500
CoexpressionAtlaskidney_P3_CapMes_Crym_top-relative-expression-ranked_500

CRIM1 LAMB1 CNKSR2 SLIT2 MET FBN2 TENM4 HMCN1 SCUBE3 DISP1 NOTCH1 NOTCH2

6.68e-0737011312gudmap_kidney_P3_CapMes_Crym_500
CoexpressionAtlasdev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_1000

FRAS1 TRPS1 LAMA1 LAMB1 ACVR1C ITGA9 SLIT2 THBD FBLN1 SCUBE1 FBN2 TENM4 HMCN1 TIMP2 LRP1 LTBP4 NOTCH2

7.51e-0777711317gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_1000
CoexpressionAtlasStromal Cells, BEC.MLN, gp38- CD31+, Lymph Node, avg-5

TSPAN12 VWF CRIM1 LAMA5 LAMB1 CDC42BPB MET THBD HEG1 PXDN LTBP4 NOTCH4 CCN3

9.52e-0745611313GSM777032_500
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_top-relative-expression-ranked_1000

TRPS1 LAMA1 LAMB1 CNKSR2 SLIT2 NELL1 FBLN1 NELL2 SCUBE1 HEG1 FBN2 TENM4 HMCN1 TIMP2 GPC4 LRP1 LTBP4

1.06e-0679711317gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_1000
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_500

TRPS1 LAMA1 ITGA9 SLIT2 THBD SCUBE1 FBN2 HMCN1 LRP1 LTBP4 NOTCH2

3.19e-0635611311gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_500
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_1000

TRPS1 LAMA1 LAMB1 ITGA9 SLIT2 THBD FBLN1 SCUBE1 FBN2 TENM4 PXDN HMCN1 GPC4 LRP1 LTBP4 NOTCH2

3.35e-0677311316gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_1000
CoexpressionAtlaskidney_adult_RenalCapsule_top-relative-expression-ranked_1000

CRISPLD2 FRAS1 CRIM1 GRN TRIM21 CNKSR2 MET THBD FBLN1 HEG1 HMCN1 TIMP2 GPC4 LRP1 LRP2 LTBP4

3.64e-0677811316gudmap_kidney_adult_RenalCapsule_1000
CoexpressionAtlaskidney_P4_CapMesRenVes_Crym_top-relative-expression-ranked_200

FRAS1 CRIM1 LAMA1 CNKSR2 MET FBN2 SCUBE3 NOTCH1

4.45e-061751138gudmap_kidney_P4_CapMesRenVes_Crym_200
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#3_top-relative-expression-ranked_200

ITGA9 SLIT2 THBD HMCN1 LRP1 LTBP4

5.01e-06821136gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k3_200
CoexpressionAtlasStromal Cells, LEC.SLN, gp38+ CD31+, Lymph Node, avg-4

TSPAN12 CDC42BPA CRIM1 LAMB1 ITGA9 CDC42BPB MET THBD PXDN HMCN1 TIMP2 LTBP4

5.07e-0645011312GSM777063_500
CoexpressionAtlasStromal Cells, BEC.SLN, gp38- CD31+, Lymph Node, avg-4

TSPAN12 VWF CRIM1 LAMA5 LAMB1 CDC42BPB MET THBD PXDN LTBP4 NOTCH4 CCN3

6.20e-0645911312GSM777037_500
CoexpressionAtlasDevelopingKidney_e14.5 whole kidney - wildtype_emap-6674_top-relative-expression-ranked_500

CRIM1 LAMA1 ZDHHC14 LAMB1 CUBN GPC4 LRP2 CORIN FHL2 NOTCH1 PCSK9

6.72e-0638511311gudmap_developingKidney_e14.5 whole kidney - wildtype_emap-6674_500
CoexpressionAtlasStromal Cells, FRC.MLN, gp38+ CD31- CD140a+, Lymph Node, avg-5

CRISPLD2 LAMA5 LAMB1 THBD FBLN1 PXDN HMCN1 TIMP2 GPC4 LRP1 LTBP4 NOTCH3

7.22e-0646611312GSM777050_500
CoexpressionAtlasdev gonad_e12.5_F_VasAssMesen_MafB_top-relative-expression-ranked_500

TSPAN12 TRPS1 LAMA1 SLIT2 NELL1 SCUBE1 FBN2 TENM4 HMCN1 GPC4 LRP1

7.23e-0638811311gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_500
CoexpressionAtlaskidney_P3_CapMes_Crym_top-relative-expression-ranked_1000

CRIM1 TRPS1 LAMB1 CNKSR2 LYST SLIT2 MET NELL1 FBN2 TENM4 HMCN1 SCUBE3 DISP1 NOTCH1 NOTCH2

1.03e-0574911315gudmap_kidney_P3_CapMes_Crym_1000
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#3_top-relative-expression-ranked_1000

LAMA1 LAMB1 ITGA9 SLIT2 THBD FBLN1 TENM4 HMCN1 LRP1 LTBP4

1.26e-0533611310gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k3_1000
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_200

ITGA9 SLIT2 THBD SCUBE1 HMCN1 LRP1 LTBP4

1.32e-051461137gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_200
CoexpressionAtlaskidney_P3_CapMes_Crym_k-means-cluster#2_top-relative-expression-ranked_500

LAMB1 CNKSR2 SLIT2 FBN2 TENM4 SCUBE3 NOTCH1

1.44e-051481137gudmap_kidney_P3_CapMes_Crym_k2_500
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_500

TSPAN12 TRPS1 LAMA1 ACVR1C ITGA9 SLIT2 SCUBE1 FBN2 TENM4 HMCN1 LRP1

1.45e-0541811311gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_500
CoexpressionAtlasdev gonad_e11.5_F_GonadVasMes_Flk_k-means-cluster#3_top-relative-expression-ranked_1000

TSPAN12 FRAS1 TRPS1 LAMA1 ACVR1C SLIT2 FBN2 TENM4 HMCN1 LRP1

1.98e-0535411310gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_k3_1000
CoexpressionAtlaskidney_P4_CapMesRenVes_Crym_k-means-cluster#3_top-relative-expression-ranked_200

FRAS1 LAMA1 CNKSR2 SCUBE3 NOTCH1

1.98e-05621135gudmap_kidney_P4_CapMesRenVes_Crym_k3_200
CoexpressionAtlasdev gonad_e13.5_M_InterstitTestis_Sma_k-means-cluster#1_top-relative-expression-ranked_500

LAMA1 ITGA9 SLIT2 THBD HMCN1 LRP1 LTBP4

2.03e-051561137gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_k1_500
CoexpressionAtlasStromal Cells, Fi.Sk, gp38+ CD140a+, Skin, avg-4

LAMB1 SNED1 SLIT2 FBLN1 PXDN HMCN1 TIMP2 GPC4 LRP1 LTBP4 CCN3

2.19e-0543711311GSM777046_500
CoexpressionAtlaskidney_P3_CapMes_Crym_k-means-cluster#4_top-relative-expression-ranked_200

CNKSR2 FBN2 TENM4 SCUBE3 NOTCH2

2.50e-05651135gudmap_kidney_P3_CapMes_Crym_k4_200
CoexpressionAtlasStromal Cells, Fi.MTS15+.Th, CD45- PDGFRa+ MTS15+, Thymus, avg-3

CRISPLD2 CDC42BPA LAMB1 SLIT2 THBD FBLN1 PXDN TIMP2 GPC4 LRP1 LTBP4

2.58e-0544511311GSM777043_500
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k-means-cluster#4_top-relative-expression-ranked_1000

LAMB1 SLIT2 FBLN1 HEG1 HMCN1 LRP1 LTBP4

3.27e-051681137gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k4_1000
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_1000

TSPAN12 TRPS1 LAMA1 ACVR1C ITGA9 SLIT2 FBLN1 SCUBE1 FBN2 TENM4 PXDN HMCN1 GPC4 LRP1 NOTCH2

3.28e-0582711315gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_1000
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_top-relative-expression-ranked_1000

TSPAN12 TRPS1 LAMA1 ITGA9 SLIT2 NELL1 SCUBE1 HEG1 FBN2 TENM4 HMCN1 GPC4 LRP1 LTBP4

3.89e-0574011314gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_1000
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#3_top-relative-expression-ranked_500

LAMA1 SLIT2 SCUBE1 FBN2 HMCN1 LRP1

4.87e-051221136gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k3_500
CoexpressionAtlasFacebaseRNAseq_e9.5_Olfactory Placode_top-relative-expression-ranked_1000

TSPAN12 FRAS1 ERBB3 VWF TRPS1 LAMA5 SLCO4A1 LRP8 SNED1 MET NELL2 GPC4 SCUBE3 LRP2 LTBP4 RNF208

5.69e-0597311316Facebase_RNAseq_e9.5_Olfactory Placode_1000
CoexpressionAtlasdev gonad_e11.5_F_GonMes_Sma_k-means-cluster#4_top-relative-expression-ranked_1000

TSPAN12 TRPS1 LAMA1 ACVR1C SLIT2 FBLN1 TENM4 HMCN1 LRP1

6.40e-053271139gudmap_dev gonad_e11.5_F_GonMes_Sma_k4_1000
CoexpressionAtlasdev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_1000

LAMA1 LAMB1 ACVR1C ITGA9 SLIT2 THBD SCUBE1 TENM4 HMCN1 TIMP2 GPC4 LRP1 LTBP4 NOTCH2

8.18e-0579311314gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_1000
CoexpressionAtlaskidney_P0_JuxtaGlom_Ren1_top-relative-expression-ranked_1000

CRIM1 LAMA1 ZDHHC14 LAMA5 CUBN ITGA9 MET TIMP2 HECTD2 GPC4 SCUBE3 LRP2 CORIN NOTCH2 NOTCH3

9.08e-0590511315gudmap_kidney_P0_JuxtaGlom_Ren1_1000
CoexpressionAtlasDevelopingKidney_e15.5_S-shaped body_emap-27855_top-relative-expression-ranked_1000

LAMA1 ZDHHC14 LAMA5 CUBN SLC26A1 SLC25A51 MET TENM4 GPC4 SCUBE3 LRP2 CORIN NOTCH1 PCSK9

1.04e-0481111314gudmap_developingKidney_e15.5_S-shaped body_1000
CoexpressionAtlasdev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_500

LAMA1 ITGA9 SLIT2 THBD SCUBE1 TENM4 HMCN1 LRP1 LTBP4

1.36e-043611139gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_500
CoexpressionAtlasdev gonad_e13.5_M_DevVasTestis_Flk_k-means-cluster#4_top-relative-expression-ranked_1000

LAMA1 LAMB1 ITGA9 THBD HMCN1 LTBP4

1.42e-041481136gudmap_dev gonad_e13.5_M_gudmap_devVasTestis_Flk_k4_1000
CoexpressionAtlasStromal Cells, FRC.SLN, gp38+ CD31- CD140a+, Lymph Node, avg-4

LAMB1 SNED1 THBD FBLN1 PXDN TIMP2 GPC4 LRP1 LTBP4 NOTCH3

1.61e-0445511310GSM777055_500
CoexpressionAtlaskidney_P0_JuxtaGlom_Ren1_top-relative-expression-ranked_500

CRIM1 ZDHHC14 LAMA5 CUBN MET GPC4 LRP2 CORIN NOTCH2 NOTCH3

1.63e-0445611310gudmap_kidney_P0_JuxtaGlom_Ren1_500
CoexpressionAtlaskidney_adult_RenMedVasc_Tie2_top-relative-expression-ranked_1000

TSPAN12 CRIM1 ZDHHC14 SLCO4A1 XIAP DGKE GRN TRIM21 MET THBD HEG1 TNFRSF1A NOTCH1 NOTCH4

1.69e-0485011314gudmap_kidney_adult_RenMedVasc_Tie2_1000
CoexpressionAtlasFacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_1000

CRISPLD2 FRAS1 VWF GARNL3 TRPS1 SLCO4A1 SLC5A2 LRP8 SNED1 SLIT2 MET NELL1 NELL2 TIMP2 LTBP4

1.99e-0497211315Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_1000
CoexpressionAtlasDevelopingKidney_e14.5 whole kidney - wildtype_emap-6674_top-relative-expression-ranked_1000

CRIM1 LAMA1 ZDHHC14 LAMB1 CUBN SLC25A51 GPC4 LRP2 CORIN HERC1 FHL2 NOTCH1 PCSK9

2.06e-0476111313gudmap_developingKidney_e14.5 whole kidney - wildtype_emap-6674_1000
CoexpressionAtlasfacebase_RNAseq_e14.5_palate_poster_proximal_ERK2_WT_2500_K2

VWF CDC42BPA GARNL3 FSTL3 TRPS1 CNKSR2 LRP8 NELL1 FBN2 TENM4 HMCN1 PKD1 NFYC LRP1 TNFRSF13B TNFRSF1A ULK2

2.18e-04120811317facebase_RNAseq_e14.5_palate_poster_proximal_ERK2_WT_2500_K2
CoexpressionAtlasdev gonad_e11.5_M_GonMes_Sma_k-means-cluster#3_top-relative-expression-ranked_1000

TRPS1 LAMA1 ACVR1C SLIT2 SCUBE1 TENM4 HMCN1 LRP1

2.62e-043111138gudmap_dev gonad_e11.5_M_GonMes_Sma_k3_1000
CoexpressionAtlaskidney_P3_CapMes_Crym_top-relative-expression-ranked_200

CNKSR2 FBN2 TENM4 HMCN1 SCUBE3 NOTCH2

2.64e-041661136gudmap_kidney_P3_CapMes_Crym_200
CoexpressionAtlasFacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_2500_k-means-cluster#5

TSPAN12 FRAS1 ERBB3 LAMA5 GRN MAMDC4 MET SCUBE3 RNF208

3.24e-044061139Facebase_RNAseq_e10.5_Olfactory Pit_2500_K5
CoexpressionAtlaskidney_e15.5_Podocyte_MafB_top-relative-expression-ranked_500

FRAS1 TRPS1 LAMA1 CUBN MET NELL2 SCUBE3 LRP2 CORIN

3.60e-044121139gudmap_kidney_e15.5_Podocyte_MafB_500
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#4_top-relative-expression-ranked_500

LAMA1 ITGA9 SLIT2 THBD LRP1 LTBP4

4.32e-041821136gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k4_500
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_MedNas_2500_K1

TRPS1 LAMA1 SLCO4A1 ACVR1C LRP8 SLIT2 DZANK1 PRDM9 HEG1 HECTD2 PTCH2 HERC1 ULK2 NOTCH1 RNF208

4.98e-04106011315facebase_RNAseq_e10.5_Emin_MedNas_2500_K1
CoexpressionAtlasAravindRamakr_EmbryoidBody-LF_top-relative-expression-ranked_1000_k-means-cluster#4

CRISPLD2 LAMA1 CRB1 NELL1 SCUBE1 TENM4 HMCN1 SCUBE3 LRP2

5.16e-044331139Arv_EB-LF_1000_K4
CoexpressionAtlasdev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k-means-cluster#4_top-relative-expression-ranked_1000

LAMA1 SLIT2 HEG1 HMCN1 LRP1

5.51e-041251135gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k4_1000
CoexpressionAtlasFacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_1000

CRISPLD2 FRAS1 VWF GARNL3 TRPS1 SLCO4A1 LRP8 SNED1 SLIT2 MET NELL1 NELL2 TIMP2 LTBP4

6.20e-0496711314Facebase_RNAseq_e8.5_Paraxial Mesoderm_1000
CoexpressionAtlasFacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_1000

CRISPLD2 VWF GARNL3 TRPS1 SLCO4A1 LRP8 SNED1 SLIT2 MET NELL1 NELL2 TIMP2 LTBP4 RNF208

6.20e-0496711314Facebase_RNAseq_e9.5_Maxillary Arch_1000
CoexpressionAtlasFacebaseRNAseq_e9.5_Facial Mesenchyne_top-relative-expression-ranked_1000

CRISPLD2 VWF GARNL3 TRPS1 SLCO4A1 MAMDC4 LRP8 SNED1 SLIT2 MET NELL1 NELL2 TIMP2 LTBP4

6.27e-0496811314Facebase_RNAseq_e9.5_Facial Mesenchyne_1000
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_top-relative-expression-ranked_500

LAMA1 SLIT2 NELL1 SCUBE1 FBN2 HMCN1 GPC4 LRP1

6.53e-043571138gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_500
CoexpressionAtlasdev gonad_e12.5_M_InterstitTestis_Sma_k-means-cluster#2_top-relative-expression-ranked_500

LAMA1 ITGA9 HMCN1 LRP1 LTBP4

6.59e-041301135gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_k2_500
CoexpressionAtlasdev gonad_e13.5_M_InterstitTestis_Sma_k-means-cluster#1_top-relative-expression-ranked_1000

FRAS1 TRPS1 ACVR1C SCUBE1 FBN2 TENM4

6.91e-041991136gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_k1_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_1000

TSPAN12 ERBB3 VWF LAMA5 SLCO4A1 LRP8 SNED1 SLIT2 MET NELL2 SCUBE3 LRP2 LTBP4 RNF208

7.36e-0498411314Facebase_RNAseq_e10.5_Olfactory Pit_1000
CoexpressionAtlaskidney_adult_Mesangium_Meis_top-relative-expression-ranked_1000

TSPAN12 CDC42BPA CRIM1 ZDHHC14 TRIM21 ITGA9 LYST HEG1 TIMP2 HECTD2 LRP1 FHL2 NOTCH3

7.49e-0487211313gudmap_kidney_adult_Mesangium_Meis_1000
CoexpressionAtlasMesoderm Day 5-reprogram_OSKM-L_vs_Mesoderm Day 5-reprogram_NA-Confounder_removed-fold2.0_adjp0.05

CRIM1 LAMA5 LRP8 FBN2 NOTCH1 MEGF10 NOTCH3

7.72e-042811137PCBC_ratio_MESO-5_from-OSKM-L_vs_MESO-5_from-ESC_cfr-2X-p05
CoexpressionAtlasMesoderm Day 5-method_mRNA_vs_Mesoderm Day 5-method_NA-Confounder_removed-fold2.0_adjp0.05

CRIM1 LAMA5 LRP8 FBN2 NOTCH1 MEGF10 NOTCH3

7.72e-042811137PCBC_ratio_MESO-5_from-mRNA_vs_MESO-5_from-ESC_cfr-2X-p05
CoexpressionAtlasFacebaseRNAseq_e9.5_Olfactory Placode_top-relative-expression-ranked_1000_k-means-cluster#3

TSPAN12 FRAS1 ERBB3 LAMA5 MET SCUBE3 RNF208

8.05e-042831137Facebase_RNAseq_e9.5_Olfactory Placode_1000_K3
CoexpressionAtlasDevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_top-relative-expression-ranked_1000

CRISPLD2 TRPS1 XIAP ITGA9 SLIT2 SETDB1 FBLN1 FBN2 HECTD2 FHL2 MEGF10 CCN3

8.41e-0477211312gudmap_developingKidney_e15.5_Ureteral Smooth Musc_1000
CoexpressionAtlasdev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_500

LAMA1 ACVR1C ITGA9 SCUBE1 TENM4 HMCN1 LRP1 LTBP4

8.67e-043731138gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_500
CoexpressionAtlaskidney_P2_CapMes_Crym_top-relative-expression-ranked_500

LYST MET NELL1 FBN2 HMCN1 DISP1 NOTCH2

9.47e-042911137gudmap_kidney_P2_CapMes_Crym_500
CoexpressionAtlasdev gonad_e12.5_F_VasAssMesen_MafB_top-relative-expression-ranked_1000

TSPAN12 TRPS1 LAMA1 SLIT2 NELL1 SCUBE1 FBN2 TENM4 HMCN1 GPC4 LRP1 NOTCH2

9.51e-0478311312gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_1000
CoexpressionAtlasDevelopingKidney_e13.5_podocyte cells_emap-27773_k-means-cluster#1_top-relative-expression-ranked_500

SNED1 FBLN1 CORIN MEGF10 CCN3

9.81e-041421135gudmap_developingKidney_e13.5_podocyte cells_500_k1
CoexpressionAtlasFacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_500_k-means-cluster#3

TSPAN12 ERBB3 LAMA5 SCUBE3 RNF208

1.04e-031441135Facebase_RNAseq_e10.5_Olfactory Pit_500_K3
CoexpressionAtlasdev gonad_e12.5_F_VasAssocMesStromOvary_Sma_top-relative-expression-ranked_500

TRPS1 LAMA1 CNKSR2 SCUBE1 FBN2 HMCN1 GPC4 LRP1

1.06e-033851138gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_500
CoexpressionAtlasDevelopingKidney_e15.5_Proximal Tubules_emap-28005_top-relative-expression-ranked_500

TRPS1 LAMA1 LAMB1 XIAP CUBN SLC5A2 LRP2 PCSK9

1.14e-033891138gudmap_developingKidney_e15.5_Proximal Tubules_500
CoexpressionAtlasFacebaseRNAseq_e9.5_Olfactory Placode_top-relative-expression-ranked_2500_k-means-cluster#5

TSPAN12 FRAS1 ERBB3 LAMA5 GRN MET SCUBE3 RNF208

1.17e-033911138Facebase_RNAseq_e9.5_Olfactory Placode_2500_K5
CoexpressionAtlasdev gonad_e11.5_F_GonadVasMes_Flk_k-means-cluster#4_top-relative-expression-ranked_500

TSPAN12 TRPS1 ACVR1C FBN2 TENM4

1.18e-031481135gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_k4_500
CoexpressionAtlaskidney_P1_CapMes_Crym_k-means-cluster#2_top-relative-expression-ranked_100

MET HMCN1

1.23e-03101132gudmap_kidney_P1_CapMes_Crym_k2_100
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_MedNas_2500

TRPS1 LAMA1 SLCO4A1 ACVR1C LRP8 SLIT2 DZANK1 PRDM9 SCUBE1 HEG1 HECTD2 PTCH2 LRP2 HERC1 ULK2 NOTCH1 RNF208

1.29e-03141411317facebase_RNAseq_e10.5_Emin_MedNas_2500
CoexpressionAtlasMesoderm Day 30-reprogram_OSK-L-l-p53KD_vs_Mesoderm Day 30-reprogram_NA-Confounder_removed-fold2.0_adjp0.05

CRISPLD2 SLIT2 SCUBE3 LRP2

1.31e-03891134PCBC_ratio_MESO-30_from-OSK-L-l-p53KD_vs_MESO-30_from-ESC_cfr-2X-p05
CoexpressionAtlasMesoderm Day 30-method_episomal_vs_Mesoderm Day 30-method_NA-Confounder_removed-fold2.0_adjp0.05

CRISPLD2 SLIT2 SCUBE3 LRP2

1.31e-03891134PCBC_ratio_MESO-30_from-episomal_vs_MESO-30_from-ESC_cfr-2X-p05
CoexpressionAtlasfacebase_RNAseq_e14.5_palate_poster_distal_ERK2_WT_2500_K1

VWF TRPS1 XIAP LRP8 TMEM260 SNED1 MET NELL1 FBN2 TENM4 HMCN1 HECTD2 TNFRSF13B LTBP4 ULK2

1.31e-03116611315facebase_RNAseq_e14.5_palate_poster_distal_ERK2_WT_2500_K1
CoexpressionAtlasJC_fibro_top-relative-expression-ranked_2500_k-means-cluster#5

CRISPLD2 CRIM1 SLC5A2 SNED1 SLIT2 FBLN1 HEG1 TIMP2 KRTAP1-5 LRP1 SCUBE3 CCN3

1.32e-0381411312JC_fibro_2500_K5
CoexpressionAtlaskidney_e15.5_Podocyte_MafB_top-relative-expression-ranked_1000

FRAS1 TRPS1 LAMA1 CNKSR2 CUBN SLIT2 MET NELL2 GPC4 SCUBE3 LRP2 CORIN

1.32e-0381411312gudmap_kidney_e15.5_Podocyte_MafB_1000
CoexpressionAtlaskidney_P0_JuxtaGlom_Ren1_k-means-cluster#4_top-relative-expression-ranked_500

LAMA5 GPC4 CORIN NOTCH2 NOTCH3

1.45e-031551135gudmap_kidney_P0_JuxtaGlom_Ren1_k4_500
CoexpressionAtlaskidney_P3_CapMes_Crym_k-means-cluster#4_top-relative-expression-ranked_1000

TRPS1 LAMB1 CNKSR2 SLIT2 FBN2 TENM4 SCUBE3

1.52e-033161137gudmap_kidney_P3_CapMes_Crym_k4_1000
CoexpressionAtlasFacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_1000_k-means-cluster#4

GARNL3 LRP8 SLIT2 NELL2 TIMP2 LTBP4

1.52e-032321136Facebase_RNAseq_e9.5_Maxillary Arch_1000_K4
CoexpressionAtlasDevelopingGonad_P2_testes_emap-30171_top-relative-expression-ranked_500

CRIM1 LAMB1 LAMC3 RNF114 THBD TIMP2 TEX101 LTBP4

1.54e-034081138gudmap_developingGonad_P2_testes_500
CoexpressionAtlaskidney_adult_RenalCapsule_top-relative-expression-ranked_500

CRIM1 MET HEG1 HMCN1 TIMP2 LRP1 LRP2 LTBP4

1.54e-034081138gudmap_kidney_adult_RenalCapsule_500
CoexpressionAtlasDevelopingGonad_e18.5_testes_emap-11164_top-relative-expression-ranked_500

CRIM1 LAMB1 LAMC3 RNF114 THBD TIMP2 TEX101 LTBP4

1.63e-034121138gudmap_developingGonad_e18.5_testes_500
CoexpressionAtlasDevelopingKidney_e15.5_early proxim tubul_emap-28005_k-means-cluster#1_top-relative-expression-ranked_200

CUBN SLC5A2 LRP2

1.66e-03441133gudmap_developingKidney_e15.5_early proxim tubul_200_k1
CoexpressionAtlasDevelopingKidney_e15.5_Cap mesenchyme_emap-27738_top-relative-expression-ranked_200

XIAP LRP8 NELL1 DISP1 MEGF10

1.67e-031601135gudmap_developingKidney_e15.5_Cap mesenchyme_200
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_500_k-means-cluster#5

GARNL3 SLC5A2 SLIT2 PRDM9 SCUBE1

1.76e-031621135Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_500_K5
ToppCellCOVID-19-Heart-Fib_2|Heart / Disease (COVID-19 only), tissue and cell type

TRPS1 LAMB1 SNED1 SLIT2 FBLN1 TENM4 PXDN TIMP2 LRP1 LTBP4 NOTCH2

3.47e-1219411511d91c9f2ec47319051fc398320693fddbe8bbd4d6
ToppCellCOVID-19-Heart-Fib_1|Heart / Disease (COVID-19 only), tissue and cell type

TRPS1 LAMB1 SNED1 SLIT2 FBLN1 TENM4 PXDN TIMP2 LRP1 LTBP4 NOTCH2

3.67e-1219511511f423baa36ac7cdc383c033e35a7d17e6bf913323
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 LAMA1 CNKSR2 SSPOP FBN2 TENM4 HMCN1 LRP2 USH2A OTOG

5.26e-11184115102cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 LAMA1 CNKSR2 SSPOP FBN2 TENM4 HMCN1 LRP2 USH2A OTOG

5.26e-1118411510ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 LAMA1 CNKSR2 SSPOP FBN2 TENM4 HMCN1 LRP2 USH2A OTOG

5.26e-11184115102b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellTracheal-10x5prime-Stromal-Peri/Epineurial_|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FSTL3 LAMB1 SNED1 SCUBE1 FBN2 TIMP2 LRP1 PTCH2 SCUBE3 LTBP4

1.03e-10197115102cb1f557ce1400398975de94638126b4522567f3
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CRISPLD2 MATN3 LAMA5 LAMB1 NELL1 FBN2 PXDN SCUBE3 FHL2 LTBP4

1.03e-10197115101da8ba5bbab232add6e43ad78b15c2339d0c2bc3
ToppCellTracheal-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FSTL3 CNKSR2 SNED1 SCUBE1 TIMP2 LRP1 SCUBE3 LTBP4 DISP1 PCSK9

1.14e-1019911510fbec5c034576cb1adaf05f6f97cc5525d19e0c1b
ToppCellmedial-2-mesenchymal|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CRISPLD2 MATN3 LAMB1 LAMC3 SLIT2 FBLN1 GPC4 FHL2 LTBP4 NOTCH3

1.19e-1020011510a9d8aa5bcf383d98a9e2eaf4b1f8466982d6b088
ToppCellmedial-mesenchymal|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CRISPLD2 MATN3 LAMB1 LAMC3 SLIT2 FBLN1 GPC4 FHL2 LTBP4 NOTCH3

1.19e-10200115104f19e1e40966e27779bf77e8c170ed3ecc24353e
ToppCellControl_saline-Mesenchymal_myocytic-Pericyte-Pericyte_2|Control_saline / Treatment groups by lineage, cell group, cell type

CRISPLD2 CRIM1 LAMB1 LAMC3 SLIT2 FBN2 GPC4 LRP1 NOTCH2 NOTCH3

1.19e-1020011510bc8949eb34482aca166c4602ff6ab876cb4c2c3c
ToppCellCOVID-19-Heart-Fib_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

TRPS1 LAMB1 SNED1 SLIT2 FBLN1 TENM4 PXDN LRP1 LTBP4

1.54e-091881159fe361215f4ba841aa5e1e581fb56f2f4d3ccd201
ToppCellMesenchymal-matrix_fibroblast_1_cell|World / Lineage, Cell type, age group and donor

CRISPLD2 FRAS1 ZDHHC14 LAMB1 CNKSR2 SNED1 SLIT2 FBLN1 HMCN1

1.94e-091931159acad568621ed677031797b8c2e34dafea798d681
ToppCellfacs-Thymus-Thymus_Epithelium|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 LAMB1 THBD FBLN1 HMCN1 GPC4 LRP1 LRP2 LTBP4

2.22e-0919611596bc1187dfc4860a4e09032d7ea87ba3d9fe9f363
ToppCellfacs-Thymus-Thymus_Epithelium-18m|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 LAMB1 THBD FBLN1 HMCN1 GPC4 LRP1 LRP2 LTBP4

2.22e-091961159c8c89e469402e11aa2a9561e859b6fd1fb66c39b
ToppCellASK452-Mesenchymal-Fibroblast|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

CRISPLD2 LAMB1 LAMC3 SLIT2 FBLN1 HMCN1 TIMP2 LTBP4 NOTCH3

2.54e-0919911594d0bf2a4bd97e5a3bfe4570a201cc21bb9c4c1f6
ToppCellASK452-Mesenchymal|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

CRISPLD2 LAMB1 LAMC3 SLIT2 FBLN1 HMCN1 TIMP2 LTBP4 NOTCH3

2.54e-09199115993e85e3731a9ece9aee3eb82c5dfdad331ee62d6
ToppCellTracheal-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CRISPLD2 LAMB1 LAMC3 FBLN1 HMCN1 TIMP2 LRP1 CORIN LTBP4

2.65e-0920011598ab0051544ea32eb8b3f7f8ba7582deaf8bf26c0
ToppCellParenchymal-10x5prime-Stromal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CRISPLD2 FSTL3 LAMB1 LAMC3 SLIT2 FBLN1 HMCN1 LTBP4 NOTCH3

2.65e-0920011592e525c0d9684e7a2275edb04e1addb6fc6a872e5
ToppCellBiopsy_Other_PF-Mesenchymal|Biopsy_Other_PF / Sample group, Lineage and Cell type

CRISPLD2 FSTL3 LAMB1 SLIT2 FBLN1 HMCN1 FHL2 LTBP4 NOTCH3

2.65e-092001159d6fcdd48858b53b5a8d18ae14b2dc4d9af41b070
ToppCellwk_08-11-Mesenchymal-Fibroblast-Alveolar_fibro|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

CNKSR2 SLC26A1 SLIT2 FBLN1 TENM4 HECTD2 LRP1 LTBP4

1.23e-08166115865dafed953b01a9830b54309af75c7a561e88336
ToppCellnormal_Lung-Fibroblasts-Pericytes|Fibroblasts / Location, Cell class and cell subclass

TSPAN12 CRIM1 MATN3 LAMB1 LAMC3 GPC4 DISP1 NOTCH3

1.48e-081701158d69c0ea4cb6b204f19d0a5d2164afb42184779ac
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LAMB4 ZDHHC14 SLCO4A1 LYST SNED1 MET HMCN1 ULK2

2.51e-081821158a8cc56f32efe180e8fb5d69dbe606a794b3db700
ToppCellPND07-28-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_C|PND07-28-samps / Age Group, Lineage, Cell class and subclass

ITGA9 FBLN1 FBN2 TENM4 PXDN HMCN1 GPC4 MEGF10

2.85e-081851158427176ad9ab8d9511200fb0a132cfd1e835fe35c
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma-6|TCGA-Breast / Sample_Type by Project: Shred V9

CRISPLD2 MATN3 LAMB1 HEG1 TENM4 HMCN1 TIMP2 CORIN

3.10e-081871158a96495803ba13fcfadd1d83b3cf5774f3fed0a20
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CRISPLD2 LAMB1 SNED1 SLIT2 NELL1 FBLN1 LRP1 LTBP4

3.37e-0818911582a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

VWF MATN3 LAMB1 CUBN HEG1 PXDN NOTCH4 CCN3

3.51e-08190115806bfb62b94b0faf467ef93d5bc5d08924c770098
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CRISPLD2 LAMB1 SNED1 SLIT2 NELL1 FBLN1 LRP1 LTBP4

3.51e-081901158d60395739458d7f47a3350ade751fe3819500320
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CRISPLD2 LAMB1 SNED1 SLIT2 NELL1 FBLN1 LRP1 LTBP4

3.65e-081911158b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CRISPLD2 LAMC3 ITGA9 FBLN1 PXDN LRP1 FHL2 LTBP4

3.65e-08191115839092a0aff8097617820c59f5fea9ee2bb4f63a2
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CRISPLD2 LAMC3 ITGA9 FBLN1 PXDN LRP1 FHL2 LTBP4

3.65e-081911158ee5f1b1c59029c46cbb1a00935c03b9317bb9da9
ToppCellLPS_only-Stromal_mesenchymal|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CRISPLD2 LAMB1 SNED1 SLIT2 NELL1 FBLN1 LRP1 LTBP4

3.81e-081921158162d8b5858d150ecbbd1c9bf2b19c6c9cd50a158
ToppCellCOVID-19-Heart-Fib_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

VWF TRPS1 LAMB1 SNED1 SLIT2 TENM4 PXDN LRP1

3.81e-08192115860b1312e84f6d6448365a952469c506c00b5fe93
ToppCell3'-Distal_airway-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

VWF FSTL3 CRIM1 SLCO4A1 THBD HEG1 TNFRSF1A NOTCH4

3.96e-081931158c0f0052c24b7fe9e21d2bc6c38047a8e755f87b6
ToppCellILEUM-inflamed-(8)_Smooth_muscle_cells|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

CRISPLD2 LAMB4 CDC42BPA LAMB1 FBLN1 PXDN TIMP2 FHL2

3.96e-081931158084c88f08ce0ecd6c9f4334caed370eb2154f896
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CRISPLD2 LAMB1 SNED1 SLIT2 NELL1 FBLN1 LRP1 LTBP4

3.96e-081931158fb28717fadd06c3840636d25409ce80c9254bd34
ToppCell3'-Distal_airway-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

VWF FSTL3 CRIM1 SLCO4A1 THBD HEG1 TNFRSF1A NOTCH4

3.96e-081931158682ce63b73a7d02eef240673db67058d7507f744
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CRISPLD2 LAMC3 FBLN1 PXDN LRP1 PTCH2 FHL2 LTBP4

4.12e-08194115881713e0409e8be695ba5dfdc67a997b33435dd9e
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ZDHHC14 LAMB1 CNKSR2 SNED1 SLIT2 FBLN1 HMCN1 HECTD2

4.12e-081941158011e14d9ed1393275f892060e7708ffadcd0767f
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CRISPLD2 LAMB1 SNED1 SLIT2 NELL1 FBLN1 LRP1 LTBP4

4.12e-08194115860622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FRAS1 ZDHHC14 LAMB1 CNKSR2 SLIT2 TENM4 HMCN1 HECTD2

4.12e-08194115835f132cc38ac133be01834ed0946188aa0757eb4
ToppCellLPS-antiTNF-Stromal_mesenchymal|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CRISPLD2 LAMB1 SNED1 SLIT2 NELL1 FBLN1 LRP1 LTBP4

4.12e-0819411586e13549f697f7478b34fe71f7dd9d63c5d3db22e
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CRISPLD2 LAMB1 SNED1 SLIT2 NELL1 FBLN1 LRP1 LTBP4

4.12e-08194115889b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CRISPLD2 LAMC3 FBLN1 PXDN LRP1 PTCH2 FHL2 LTBP4

4.12e-081941158627cffe2d448e74fc5df92e74e5b922a73304137
ToppCell3'-Distal_airway-Endothelial-Blood_vessel_EC-vein_endothelial_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

VWF FSTL3 CRIM1 SLCO4A1 THBD HEG1 TNFRSF1A NOTCH4

4.29e-08195115853b83e16b350100b1d5791a9c42bd98e37cbc0af
ToppCellEpithelial_cells-AT1_cells|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

FSTL3 MATN3 LAMA5 CNKSR2 SCUBE1 HEG1 PXDN TIMP2

4.46e-0819611586c99d29162848161c1f166a032320f87a5d5a631
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CRISPLD2 LAMA5 LAMB1 NELL1 PXDN GPC4 FHL2 LTBP4

4.64e-081971158ea746772adb9df4ddb0508d4ef35f2027bf09c35
ToppCellNon-neuronal-Non-dividing-Radial_Glia-tRG|World / Primary Cells by Cluster

TSPAN12 LAMA1 HEG1 GPC4 NOTCH1 MEGF10 NOTCH2 NOTCH3

4.64e-08197115861749ccafeb938c310cff1de5ff924a1c794325a
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LAMB1 ITGA9 FBLN1 FBN2 TENM4 HMCN1 TIMP2 GPC4

4.64e-08197115826475b9e4d6bfc0ae818dea13d139888ed7e92f1
ToppCellNon-neuronal-Non-dividing-Radial_Glia-tRG-25|World / Primary Cells by Cluster

TSPAN12 LAMA1 HEG1 GPC4 NOTCH1 MEGF10 NOTCH2 NOTCH3

4.64e-0819711589d4ffa3680f92c91d0a081f9a8ec5ebfec6bdcf6
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CRISPLD2 ITGA9 TENM4 PXDN HMCN1 GPC4 FHL2 MEGF10

4.64e-081971158090a251194da3e2806989d9a522588f83f52da7f
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LAMB1 ITGA9 FBLN1 FBN2 TENM4 HMCN1 TIMP2 GPC4

4.64e-081971158155e63b33302a87393ace699b2f6d73abe9c5763
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMB1 ITGA9 SNED1 PXDN LRP1 SCUBE3 FHL2 LTBP4

4.83e-08198115809be07ebfc3e49c3858e9b74605b69cf4fc28b56
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LAMB1 ITGA9 FBLN1 FBN2 TENM4 HMCN1 TIMP2 GPC4

4.83e-081981158a4005a49cf6709b543994ceb51ecd5dc46197fa9
ToppCellILEUM-inflamed-(7)_CD36+_endothelial_cells|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

TSPAN12 VWF CRIM1 NELL1 THBD HEG1 NOTCH4 CCN3

4.83e-08198115805d6558c7990ad2277db999025a073d29b273dfc
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LAMB1 ITGA9 FBLN1 FBN2 TENM4 HMCN1 TIMP2 GPC4

4.83e-081981158a699b365d3b6149f13f02b2e2ae9b6fdce761848
ToppCellbackground-Hepatic_Stellate_cells|background / Sample and Cell Type and Tumor Cluster (all cells)

CRISPLD2 LAMB1 LAMC3 ITGA9 SLIT2 FBLN1 HMCN1 LTBP4

4.83e-081981158bd11b0e9e80449aab979a02c1023e0638c431c7c
ToppCellkidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

VWF SLCO4A1 ITGA9 THBD HEG1 TIMP2 LTBP4 NOTCH4

5.02e-081991158a3ec743b978ba8fdf1677b4971b5731f50ddd30f
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMA5 LAMB1 SLIT2 FBN2 PXDN LRP1 PTCH2 LTBP4

5.02e-081991158edba1833ef5c4ca122d7c32f97670314e005f93b
ToppCellBronchial-10x5prime-Stromal-Fibroblastic-Fibro_myofibroblast|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CRISPLD2 FSTL3 INSRR LAMB1 SNED1 SLIT2 FBLN1 PXDN

5.02e-08199115821335475bbfbad8a6943b8076a6c1c67f3eec5d3
ToppCellBronchial-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_arterial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

VWF CDC42BPA CRIM1 LAMB1 MET HEG1 LTBP4 NOTCH4

5.02e-0819911586a2943a23fdd2ec814662db7c21a0d6804a6cbbc
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MATN3 LAMB1 NELL1 FBN2 PXDN LRP1 FHL2 LTBP4

5.02e-081991158e78f661b40da34768469549b6e755d330be6bbd8
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMB1 SLIT2 NELL1 FBN2 PXDN SCUBE3 FHL2 LTBP4

5.02e-081991158137ff58897e6ada8a5a70205f66fe9110795506b
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

CRISPLD2 LAMA1 LAMB1 SLIT2 NELL1 FBLN1 LRP1 LTBP4

5.22e-0820011589b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCellParenchyma_COVID-19-Endothelial-TX-Capillary|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

TSPAN12 VWF CRIM1 SLCO4A1 THBD HEG1 PXDN NOTCH4

5.22e-0820011586c0498a5868891e8e22c03469d00669b20249b1a
ToppCellBronchial-10x5prime-Endothelial-Endothelia_vascular-VE_capillary|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TSPAN12 VWF SLCO4A1 THBD HEG1 PXDN DISP1 NOTCH4

5.22e-0820011585ab588808c1fc384019413401ab4bf9bc06bf529
ToppCellControl_saline-Mesenchymal_fibroblastic|Control_saline / Treatment groups by lineage, cell group, cell type

CRISPLD2 MATN3 LAMB1 SLIT2 NELL1 FBLN1 LRP1 LTBP4

5.22e-08200115864ae5cf6cb4fc94cf1052abd82648f6b8e6445fe
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Pericyte|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

CRISPLD2 CRIM1 LAMB1 LAMC3 SLIT2 FBN2 GPC4 NOTCH3

5.22e-0820011584e1e19214aeebbdca004de7faaf4cc9d18498591
ToppCellParenchyma_Control_(B.)-Stromal-TX-Fibroblasts-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

CRISPLD2 FRAS1 LAMB1 CNKSR2 SLIT2 FBLN1 HMCN1 LTBP4

5.22e-082001158aa1a35dcca3b799241eef4237f6eb94660e019f0
ToppCelldistal-2-mesenchymal|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CRISPLD2 MATN3 LAMB1 LAMC3 SLIT2 FBLN1 GPC4 NOTCH3

5.22e-08200115865a50f03b0027ccefb51b8f77afa283d4a3b3567
ToppCellLung_Parenchyma-Severe-Endothelial-Endothelial-Capillary-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TSPAN12 VWF CRIM1 SLCO4A1 THBD HEG1 PXDN NOTCH4

5.22e-0820011587020045b933cb104fb99b79524cb0d4734b8636d
ToppCellControl_saline-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|Control_saline / Treatment groups by lineage, cell group, cell type

CRISPLD2 LAMB1 ITGA9 MET FBLN1 GPC4 LRP1 LTBP4

5.22e-082001158a799fc7bb83ad0524362cb5010df949741fb7bf3
ToppCellILEUM-non-inflamed-(7)_CD36+_endothelial_cells|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

TSPAN12 VWF CRIM1 NELL1 THBD HEG1 NOTCH4 CCN3

5.22e-08200115845755a597725015dc3ee36f9166f9e82f6f9c603
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

CRISPLD2 FRAS1 LAMB1 CNKSR2 SLIT2 FBLN1 HMCN1 LTBP4

5.22e-082001158a510deaada669e690329183e18df02870bd204b3
ToppCellcellseq2-Mesenchymal-Fibroblastic-Fibroblastic_1-AF2|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CRISPLD2 LAMB1 SNED1 SLIT2 FBLN1 HMCN1 LRP1 LTBP4

5.22e-08200115844317fbf4d1480a37b50ab2777bf1a3e4fc0c05f
ToppCellTracheal-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CRISPLD2 LAMB1 SNED1 SLIT2 FBLN1 HMCN1 TIMP2 LRP1

5.22e-082001158b4ccffdd79526c85e5273d27b668dbddcddba1ee
ToppCellLung_Parenchyma-Severe-Endothelial-Endothelial-Capillary|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

TSPAN12 VWF CRIM1 SLCO4A1 THBD HEG1 PXDN NOTCH4

5.22e-082001158e9913511a129bb3cee85e7ebf565b951dab91542
ToppCellILEUM-non-inflamed-(7)_Endothelial_cell|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

TSPAN12 VWF CRIM1 NELL1 THBD HEG1 NOTCH4 CCN3

5.22e-082001158ec92fe4eafe527d351ee73c9735e96855ac506a3
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_only / Treatment groups by lineage, cell group, cell type

CRISPLD2 LAMA1 LAMB1 SLIT2 NELL1 FBLN1 LRP1 LTBP4

5.22e-082001158a7ef7022b8efcaedb7319b0b43d8c4e99d788fe2
ToppCellControl_saline-Mesenchymal_fibroblastic-Fibroblasts|Control_saline / Treatment groups by lineage, cell group, cell type

CRISPLD2 MATN3 LAMB1 SLIT2 NELL1 FBLN1 LRP1 LTBP4

5.22e-082001158a1fc74c1b27e104895910bc7cdce7ba33d30df7e
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-3|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

CRISPLD2 FSTL3 LAMB1 SLIT2 FBLN1 TENM4 HMCN1 LTBP4

5.22e-08200115807641f476cb1a131c2a50258b88cc13bb38c8379
ToppCellParenchyma_Control_(B.)-Stromal-TX-Fibroblasts-3|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

CRISPLD2 FSTL3 LAMB1 SLIT2 FBLN1 TENM4 HMCN1 LTBP4

5.22e-082001158343fa6ba1f52d816d2e41466f674ff8360aecd81
ToppCellcellseq2-Mesenchymal-Fibroblastic|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CRISPLD2 LAMB1 SNED1 SLIT2 FBLN1 HMCN1 LRP1 LTBP4

5.22e-0820011581c10597edd532bf172ca09870a937d35e2585081
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-3-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CRISPLD2 FSTL3 LAMB1 SLIT2 FBLN1 TENM4 HMCN1 LTBP4

5.22e-082001158d0c00cdd52c2e001aec9b935f4e981ba77d0386a
ToppCellcellseq2-Mesenchymal-Fibroblastic-Fibroblastic_1|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CRISPLD2 LAMB1 SNED1 SLIT2 FBLN1 HMCN1 LRP1 LTBP4

5.22e-082001158440dda48b09c6a8581b7ca634b0d67f1ecacf65e
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CRISPLD2 FRAS1 LAMB1 CNKSR2 SLIT2 FBLN1 HMCN1 LTBP4

5.22e-082001158dd4228cbed8a4395166a6332e08d44d88bebe3b9
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 LAMA1 CRB1 FBN2 HMCN1 LRP2 USH2A

2.00e-071601157c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 LAMA1 CRB1 FBN2 HMCN1 LRP2 USH2A

2.00e-07160115725c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l32-30|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ERBB3 SLITRK3 CNKSR2 NELL1 LRP2 GJC3 RNF208

2.37e-0716411573caf4cdaa0164907893fea61e251fd8b5fa926e4
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMB1 LAMC3 FBLN1 FBN2 TENM4 TIMP2 TNFRSF1A

2.37e-071641157d167c7a987b9b35d1e7725c803df4f9cd5380e47
ToppCellRA-01._Fibroblast_I|RA / Chamber and Cluster_Paper

CRISPLD2 MATN3 INSRR LAMB1 SLIT2 FBLN1 LTBP4

2.90e-0716911576373562ab3b1765060212a6a53d6543e7e942e80
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-6|TCGA-Ovary / Sample_Type by Project: Shred V9

CRISPLD2 LAMB1 HEG1 HMCN1 TIMP2 LRP1 MEGF10

4.12e-071781157142879e9393e721f9b05a6bb46995c9d6d713c95
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MATN3 CNKSR2 ITPRID1 SNED1 NELL1 FBLN1 LRP1

4.44e-07180115708ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCelldroplet-Limb_Muscle-Pre-Sort|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWF CRIM1 LAMA5 TIMP2 LRP2 LTBP4 NOTCH3

4.44e-071801157af2bafcd1b2082629de3ea336711add01565c4c4
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MATN3 CNKSR2 ITPRID1 SNED1 NELL1 FBLN1 LRP1

4.44e-0718011579b1de1b4711adbf9a423f4d2d08f3f4c78f1f8f4
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWF CRIM1 LAMA5 TIMP2 LRP2 LTBP4 NOTCH3

4.44e-071801157f29a995cf6e1a1836ed68b73258d9370bf3d4434
ToppCellCOVID-19-Endothelial_cells-Capillary_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

TSPAN12 ZDHHC14 LAMA5 SLCO4A1 ITPRID1 PXDN NOTCH4

4.61e-071811157c5f9c92af1384d9089c65afdf41c6feb8345a3ae
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CRISPLD2 ZDHHC14 LAMB1 SCUBE1 HMCN1 HECTD2 LTBP4

4.61e-071811157b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCellmetastatic_Brain-Fibroblasts-Myofibroblasts|metastatic_Brain / Location, Cell class and cell subclass

FSTL3 MATN3 LAMB1 FBLN1 FBN2 HMCN1 CORIN

4.61e-071811157bd0b5f74f9c81ec0f1592710774a4fdf33d9d5a9
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CRISPLD2 LAMB1 SLIT2 FBLN1 HMCN1 LRP1 LTBP4

4.79e-0718211573dfa9187e9d2bab1d199079d29209c4648220ada
ComputationalPlacenta genes.

ERBB3 VWF FSTL3 CRIM1 LAMA5 GRN SMYD5 SLC5A2 FBLN1 HEG1 FBN2 TIMP2 NFYC LRP1 NOTCH3

1.14e-074636715MODULE_38
ComputationalOvary genes.

VWF FSTL3 CRIM1 LAMB1 FBLN1 HEG1 TIMP2 PKD1 LRP1 TNFRSF13B FHL2 NOTCH3

2.37e-063686712MODULE_1
ComputationalMetal / Ca ion binding.

CRB1 SLIT2 NELL1 THBD FBLN1 FBN2 LRP1

1.78e-05133677MODULE_324
ComputationalDRG (dorsal root ganglia) genes.

ERBB3 VWF FSTL3 CRIM1 LAMA5 LAMB1 SLIT2 FBLN1 LRP1 NOTCH3

1.21e-043846710MODULE_2
ComputationalLung genes.

VWF FSTL3 CRIM1 LAMA5 GRN SLIT2 FBLN1 HEG1 TIMP2 NOTCH3

3.27e-044346710MODULE_5
ComputationalECM and collagens.

CRISPLD2 VWF LAMB1 SLIT2 FBLN1 LRP1 NOTCH3

4.80e-04225677MODULE_47
ComputationalTrachea genes.

ERBB3 VWF CRIM1 LAMA5 GRN SLIT2 FBLN1 LRP1 NOTCH3

1.02e-03415679MODULE_6
DrugAC1L1G72

LAMB4 LAMA1 LAMA5 LAMB1 LAMC3

1.36e-09111155CID000003553
DrugLG 5

LAMB4 ERBB3 LAMA1 LAMA5 LAMB1 LAMC3 GPC4

2.16e-08601157CID011840957
DrugRgd Peptide

LAMB4 VWF LAMA5 LAMB1 LAMC3 GRN ITGA9 THBD FBLN1 FBN2 CCN3

3.69e-0823911511CID000104802
DrugYIGSR

LAMB4 LAMA1 LAMA5 LAMB1 LAMC3 ITGA9 TIMP2

1.50e-07791157CID000123977
Drug1,2-dimethylhydrazine

LAMB4 LAMA1 LAMA5 LAMB1 LAMC3 PROZ MUC5AC

2.70e-07861157CID000001322
DrugAC1L1B58

LAMB4 LAMA1 LAMA5 LAMB1 LAMC3

3.25e-07291155CID000001288
DrugCC270

LAMB4 LAMA1 LAMA5 LAMB1 LAMC3 TRIM21

5.27e-07591156CID006918852
DrugLMWH

LAMB4 ERBB3 VWF LAMA1 LAMA5 LAMB1 LAMC3 SLIT2 MET THBD FBLN1 PROZ GPC4 LRP1 LRP2

1.27e-0666311515CID000000772
DrugCalcort

LAMB4 LAMA1 LAMA5 LAMB1 LAMC3

1.32e-06381155CID000026709
Drug2-amino-5-methylpyridine

LAMB4 ERBB3 LAMA1 LAMA5 LAMB1 LAMC3

2.58e-06771156CID000015348
Drugzoledronic acid

BIRC8 CYP2C9 VWF FSTL3 MATN3 LAMA1 LAMA5 SLCO4A1 LAMB1 XIAP CUBN RNF114 FBLN1 HEG1 TENM4 HMCN1 GPC4 TNFRSF1A FHL2 ULK2 NOTCH3 PCSK9

3.91e-06147211522ctd:C088658
DrugNSC 714187

LAMB4 ERBB3 LAMA1 LAMA5 LAMB1 LAMC3

4.60e-06851156CID005288693
DrugSikvav

LAMA1 LAMA5 LAMB1 TIMP2

6.07e-06241154CID005487517
DrugFenspiride hydrochloride [5053-08-7]; Up 200; 13.4uM; MCF7; HT_HG-U133A

ZDHHC14 TRIM21 SNED1 THBD DZANK1 FBLN1 HEG1 MUC6

7.59e-0619811586001_UP
DrugMeropenem [96036-03-2]; Up 200; 10.4uM; HL60; HT_HG-U133A

LAMB4 CDC42BPA FSTL3 CNKSR2 SLC5A2 FBLN1 LRP1 TNFRSF13B

8.16e-0620011586141_UP
Drugkalinin

LAMB4 LAMA1 LAMA5 LAMB1 LAMC3

8.57e-06551155CID000032518
Drugembelin

BIRC8 XIAP LYST TNFRSF1A

1.15e-05281154CID000003218
Drugpyrachlostrobin

CRISPLD2 MATN3 LAMA5 GRN TRIM21 SCUBE1 HEG1 GPC4 LRP2 TNFRSF1A NOTCH1 MEGF10 NOTCH2 NOTCH3 CCN3

1.45e-0581111515ctd:C513428
DrugAC1L1CUL

CYP2C9 VWF LRP1

1.47e-05101153CID000002070
DrugVerteporfin [129497-78-5]; Down 200; 2.8uM; MCF7; HT_HG-U133A

CRIM1 LAMB1 GRN THBD PXDN GPC4 NOTCH2

1.79e-0516111573556_DN
Drugtaxol

LAMB4 BIRC8 ERBB3 CYP2C9 CYP2C18 LAMA1 LAMA5 LAMB1 XIAP LAMC3 PKD1 CHFR

2.69e-0556011512CID000004666
Drugdysprosium

LAMB4 LAMA1 LAMA5 LAMB1 LAMC3

3.68e-05741155CID000023912
DrugIkvav

LAMA1 LAMA5 LAMB1 TIMP2

3.99e-05381154CID000131343
DrugNVP-AAD777

NELL1 NELL2 GPC4

5.46e-05151153CID006918569
Drugphthalazine

LYST MET PROZ

5.46e-05151153CID000009207
DrugAC1O0B8G

LAMB4 LAMA1 LAMA5 LAMB1 LAMC3 GRN FBN2 PCSK9

5.66e-052621158CID000091605
DrugICI182,780; Down 200; 1uM; MCF7; HT_HG-U133A

FRAS1 FSTL3 ZDHHC14 HEG1 MEGF8 TNFRSF13B FHL2

5.90e-0519411577534_DN
DrugFurazolidone [67-45-8]; Down 200; 17.8uM; MCF7; HT_HG-U133A

CYP2C9 DBF4B DGKE LYST SLC5A2 SLIT2 FBLN1

5.90e-0519411574178_DN
DrugMebeverine hydrochloride [2753-45-9]; Down 200; 8.6uM; MCF7; HT_HG-U133A

MET DZANK1 NFX1 LTBP4 MUC5AC ULK2 NOTCH2

5.90e-0519411573193_DN
DrugCefepime hydrochloride [123171-59-5]; Up 200; 7.4uM; HL60; HT_HG-U133A

CDC42BPA FSTL3 CRB1 LRP2 TNFRSF13B C8B MUC6

6.09e-0519511576159_UP
DrugCisapride [81098-60-4]; Up 200; 8.6uM; MCF7; HT_HG-U133A

FRAS1 CDC42BPA DBF4B MET THBD DZANK1 LRP2

6.29e-0519611573305_UP
DrugLiothyronine [6893-02-3]; Down 200; 6.2uM; PC3; HT_HG-U133A

CRISPLD2 DBF4B SETDB1 FBLN1 LRP1 NOTCH1 NOTCH2

6.29e-0519611576602_DN
DrugGrgds

VWF LAMA5 LAMB1 FBLN1 FHL2

6.39e-05831155CID000123811
Drug2-[(1R,2R,3S,4R,5R,6S)-2-[(2R,5S)-3-[(3S,4S,5R,6S)-4,5-dihydroxy-3-(methylamino)-6-methylol-tetrahydropyran-2-yl]-4-formyl-4-hydroxy-5-methylol-tetrahydrofuran-2-yl]oxy-5-guanidino-3,4,6-trihydroxy-cyclohexyl]guanidine

LAMB4 LAMA1 LAMA5 LAMB1 LAMC3

6.39e-05831155CID011968896
Drug0179445-0000 [211246-22-9]; Up 200; 1uM; MCF7; HT_HG-U133A

LAMB4 CNKSR2 SNED1 FBLN1 NFX1 PTCH2 LTBP4

6.50e-0519711574758_UP
DrugAtropine sulfate monohydrate [5908-99-6]; Up 200; 5.8uM; MCF7; HT_HG-U133A

CYP2C9 CRIM1 SIAH1 LYST FBLN1 LRP2 LTBP4

6.50e-0519711572761_UP
Drugimatinib

ERBB3 CYP2C9 LAMA1 INSRR XIAP ACVR1C CDC42BPB MET NELL1 LRP1

6.64e-0543011510CID000005291
DrugImidurea [39236-46-9]; Up 200; 10.4uM; PC3; HT_HG-U133A

FRAS1 CYP2C9 FSTL3 MATN3 TNFRSF13B MUC5AC NOTCH2

6.71e-0519811575062_UP
Drugprostaglandin E2; Up 200; 10uM; MCF7; HT_HG-U133A

FSTL3 LYST FBLN1 MEGF8 GPC4 NFX1 LRP2

6.71e-0519811576552_UP
DrugBethanechol chloride [590-63-6]; Up 200; 20.4uM; PC3; HT_HG-U133A

TSPAN12 CDC42BPB FBLN1 PRDM9 HEG1 NFX1 LTBP4

6.71e-0519811575114_UP
DrugChrysin [480-40-0]; Up 200; 15.8uM; MCF7; HT_HG-U133A

CNKSR2 SLC5A2 SNED1 FBLN1 TENM4 FHL2 CCN3

6.71e-0519811576485_UP
DrugSuramin sodium salt; Up 200; 10uM; PC3; HT_HG-U133A

CDC42BPA LYST DZANK1 FBLN1 HEG1 MEGF8 ULK2

7.15e-0520011577501_UP
DrugGBR 12909 dihydrochloride [67469-78-7]; Down 200; 7.6uM; MCF7; HT_HG-U133A

CRIM1 TRIM21 LYST FBLN1 LRP2 ULK2 NOTCH2

7.15e-0520011573240_DN
DrugH-9 dihydrochloride

LAMB4 LAMA1 LAMA5 LAMB1 LAMC3

9.40e-05901155CID000003544
DrugMifepristone

CRISPLD2 ERBB3 VWF FSTL3 LAMA5 SLIT2 MET FBLN1 PXDN TNFRSF1A NOTCH4

1.15e-0455311511ctd:D015735
DrugMRK 003

ERBB3 CDC42BPA SLCO4A1 GRN CDC42BPB CRB1 PXDN SCUBE3 NOTCH1 MEGF10 NOTCH2 NOTCH3 NOTCH4

1.23e-0476011513ctd:C523799
Drugbenzyloxycarbonylleucyl-leucyl-leucine aldehyde

ERBB3 VWF XIAP TENM4 PKD1 LRP2 CORIN FHL2 MUC5AC NOTCH1 RNF208

1.24e-0455811511ctd:C072553
Druggamma-secretase inhibitor I

NOTCH2 NOTCH3

1.51e-0441152CID011754711
Diseaseadenocarcinoma (implicated_via_orthology)

NOTCH1 NOTCH2 NOTCH3

1.79e-0671113DOID:299 (implicated_via_orthology)
Diseasecentral nervous system cancer (implicated_via_orthology)

NOTCH1 NOTCH2 NOTCH3

1.79e-0671113DOID:3620 (implicated_via_orthology)
DiseaseMalignant neoplasm of skin

ERBB3 NOTCH1 NOTCH2 NOTCH3 NOTCH4

2.93e-06591115C0007114
DiseaseSkin Neoplasms

ERBB3 NOTCH1 NOTCH2 NOTCH3 NOTCH4

2.93e-06591115C0037286
DiseaseGlioblastoma Multiforme

INSRR MET LTBP4 NOTCH1 NOTCH2 NOTCH3

4.06e-061111116C1621958
Diseasepulse pressure measurement

CYP2C9 FSTL3 CRIM1 TRPS1 PCDHAC1 LAMA5 ITGA9 SSPOP MET PRDM9 FBN2 TENM4 MEGF8 PKD1 LRP1 FHL2 NOTCH3 CCN3

4.41e-06139211118EFO_0005763
Diseaseintestinal cancer (implicated_via_orthology)

ERBB3 NOTCH1 NOTCH2 NOTCH3

6.29e-06321114DOID:10155 (implicated_via_orthology)
Diseasedementia (is_implicated_in)

GRN LRP8 NOTCH4

1.11e-05121113DOID:1307 (is_implicated_in)
DiseaseGlioblastoma

MET LTBP4 NOTCH1 NOTCH2 NOTCH3

1.24e-05791115C0017636
DiseaseFEV/FEC ratio

FRAS1 ERBB3 CRIM1 TRPS1 GSX2 CNKSR2 ACVR1C MET FBLN1 NELL2 HMCN1 TIMP2 LRP1 SCUBE3 HERC1 LTBP4

1.45e-05122811116EFO_0004713
DiseaseGiant Cell Glioblastoma

MET LTBP4 NOTCH1 NOTCH2 NOTCH3

1.68e-05841115C0334588
DiseaseNeoplasm of uncertain or unknown behavior of bladder

ERBB3 NOTCH1 NOTCH2

2.28e-05151113C0496930
DiseaseProteinuria

VWF CUBN LRP2

2.28e-05151113HP_0000093
DiseaseBenign neoplasm of bladder

ERBB3 NOTCH1 NOTCH2

2.28e-05151113C0154017
DiseaseCarcinoma in situ of bladder

ERBB3 NOTCH1 NOTCH2

2.28e-05151113C0154091
DiseaseCarcinoma of bladder

ERBB3 NOTCH1 NOTCH2

4.06e-05181113C0699885
DiseaseX-21258 measurement

CYP2C9 CYP2C18

4.20e-0531112EFO_0800802
Diseasecortical thickness

ERBB3 CRIM1 TRPS1 LAMA1 LAMC3 LRP8 SLIT2 NELL1 NELL2 SCUBE1 FBN2 PKD1 LRP1 ULK2

7.59e-05111311114EFO_0004840
DiseaseMacrostomia

FRAS1 PTCH2

8.37e-0541112C0024433
DiseaseCarcinoma, Pancreatic Ductal

NOTCH1 NOTCH3 NOTCH4

9.90e-05241113C0887833
Diseasecholangiocarcinoma (is_marker_for)

MET MUC5AC MUC6 NOTCH1

1.01e-04641114DOID:4947 (is_marker_for)
DiseaseSquamous cell carcinoma

MET NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.09e-041241115C0007137
DiseaseCerebral Astrocytoma

MET NOTCH1 NOTCH2

1.12e-04251113C0750935
DiseaseIntracranial Astrocytoma

MET NOTCH1 NOTCH2

1.12e-04251113C0750936
DiseaseAstrocytoma

MET NOTCH1 NOTCH2

1.12e-04251113C0004114
DiseaseGrade I Astrocytoma

MET NOTCH1 NOTCH2

1.12e-04251113C1704230
DiseaseSubependymal Giant Cell Astrocytoma

MET NOTCH1 NOTCH2

1.12e-04251113C0205768
DiseaseMixed oligoastrocytoma

MET NOTCH1 NOTCH2

1.12e-04251113C0547065
DiseasePilocytic Astrocytoma

MET NOTCH1 NOTCH2

1.12e-04251113C0334583
DiseaseJuvenile Pilocytic Astrocytoma

MET NOTCH1 NOTCH2

1.12e-04251113C0280783
DiseaseDiffuse Astrocytoma

MET NOTCH1 NOTCH2

1.12e-04251113C0280785
DiseaseChildhood Cerebral Astrocytoma

MET NOTCH1 NOTCH2

1.12e-04251113C0338070
DiseaseSchizophrenia

ERBB3 LAMA1 GRN LRP8 MET SETDB1 TENM4 LRP1 LRP2 TNFRSF1A MEGF10 NOTCH4

1.25e-0488311112C0036341
Diseasebrain cancer (implicated_via_orthology)

NOTCH1 NOTCH2 NOTCH3

1.26e-04261113DOID:1319 (implicated_via_orthology)
DiseaseGemistocytic astrocytoma

MET NOTCH1 NOTCH2

1.26e-04261113C0334581
DiseaseProtoplasmic astrocytoma

MET NOTCH1 NOTCH2

1.26e-04261113C0334580
DiseaseFibrillary Astrocytoma

MET NOTCH1 NOTCH2

1.26e-04261113C0334582
Diseasemucinous adenocarcinoma (is_marker_for)

MUC5AC MUC6

1.39e-0451112DOID:3030 (is_marker_for)
Diseaseresponse to platinum based chemotherapy, cytotoxicity measurement

FRAS1 EYS

1.39e-0451112EFO_0004647, EFO_0006952
Diseaseresponse to silica exposure, pneumoconiosis

LAMB4 LAMB1

1.39e-0451112EFO_0005853, MONDO_0015926
Diseaseretinitis pigmentosa (implicated_via_orthology)

CRB1 EYS USH2A

1.42e-04271113DOID:10584 (implicated_via_orthology)
DiseaseAnaplastic astrocytoma

MET NOTCH1 NOTCH2

1.42e-04271113C0334579
DiseaseDisorder of eye

TSPAN12 FRAS1 GRN CRB1 EYS USH2A

1.55e-042121116C0015397
Diseasecolorectal cancer (implicated_via_orthology)

NOTCH1 NOTCH2 NOTCH3

1.95e-04301113DOID:9256 (implicated_via_orthology)
DiseaseMalignant neoplasm of breast

ERBB3 VWF DGKE CUBN ITGA9 MAMDC4 SLC25A51 NFYC FHL2 NOTCH1 NOTCH2 NOTCH3 NOTCH4

2.03e-04107411113C0006142
Diseasefamilial combined hyperlipidemia (is_marker_for)

VWF THBD

2.08e-0461112DOID:13809 (is_marker_for)
Diseaseserum metabolite measurement

LAMB4 CYP2C9 CYP2C18 CDC42BPA CRIM1 LAMB1 SIAH1 LAMC3 SLIT2 CHFR FHL2 PCSK9

2.34e-0494511112EFO_0005653
Diseaselupus nephritis

GSX2 CRB1 NOTCH4

2.60e-04331113EFO_0005761
Diseaseglycine conjugate of C10H14O2 (1) measurement

CYP2C9 CYP2C18

2.91e-0471112EFO_0800655
Diseaseglycosyl ceramide (d18:1/20:0, d16:1/22:0) measurement

CORIN PCSK9

2.91e-0471112EFO_0800551
Diseaseendometrial cancer (is_marker_for)

TNFRSF1A NOTCH1 NOTCH4

3.11e-04351113DOID:1380 (is_marker_for)
Diseasetriglyceride change measurement, response to long-chain n-3 PUFA dietary supplementation

SLIT2 NELL1

3.87e-0481112EFO_0007681, EFO_0009308
Diseasecoloboma (implicated_via_orthology)

LAMB1 PTCH2

3.87e-0481112DOID:12270 (implicated_via_orthology)
Diseaselung non-small cell carcinoma (is_marker_for)

ERBB3 ITGA9 MET THBD TNFRSF1A

4.56e-041691115DOID:3908 (is_marker_for)
Diseasehemangiopericytoma (is_marker_for)

NOTCH1 NOTCH4

4.96e-0491112DOID:264 (is_marker_for)
DiseaseDermatitis, Irritant

TRIM31 TRIM10

4.96e-0491112C0162823
Diseasebringing up phlegm, sputum or mucus on most days, self-reported

NELL1 MUC5AC

4.96e-0491112EFO_0009824
Diseaseglycosyl-N-palmitoyl-sphingosine (d18:1/16:0) measurement

CORIN PCSK9

4.96e-0491112EFO_0800476
Diseaseautistic disorder (is_implicated_in)

LAMB1 MET SETDB1

5.34e-04421113DOID:12849 (is_implicated_in)
Diseaseurate measurement, bone density

FRAS1 ZDHHC14 LAMA5 SIAH1 NELL1 FBLN1 EYS USH2A NOTCH4

5.62e-046191119EFO_0003923, EFO_0004531
Diseasecystic kidney disease (implicated_via_orthology)

LAMA5 SLIT2

6.19e-04101112DOID:2975 (implicated_via_orthology)
DiseaseAtypical Hemolytic Uremic Syndrome

DGKE THBD

6.19e-04101112C2931788
Diseaseend stage renal disease (is_marker_for)

VWF THBD TNFRSF1A

6.99e-04461113DOID:783 (is_marker_for)
Diseasepolymyositis (is_marker_for)

SLIT2 TNFRSF1A

7.54e-04111112DOID:0080745 (is_marker_for)
Diseasecerebral cavernous malformation (implicated_via_orthology)

CDC42BPA CDC42BPB

7.54e-04111112DOID:0060669 (implicated_via_orthology)
DiseaseAmyotrophic Lateral Sclerosis, Familial

GSX2 XIAP OTOG

7.92e-04481113C4551993
DiseaseAmyotrophic Lateral Sclerosis, Sporadic

GSX2 XIAP OTOG

7.92e-04481113C1862941
Diseasepulmonary fibrosis (biomarker_via_orthology)

VWF MUC5AC NOTCH1

8.93e-04501113DOID:3770 (biomarker_via_orthology)
DiseaseAMYOTROPHIC LATERAL SCLEROSIS 1

GSX2 XIAP OTOG

8.93e-04501113C1862939
DiseaseStomach Neoplasms

ERBB3 MET THBD CHFR MUC6 NOTCH2

9.25e-042971116C0038356
DiseaseMalignant neoplasm of stomach

ERBB3 MET THBD CHFR MUC6 NOTCH2

9.74e-043001116C0024623
Diseasediastolic blood pressure, systolic blood pressure

CRISPLD2 CRIM1 TRPS1 GSX2 CRB1 MET TENM4 LRP1 FHL2

9.83e-046701119EFO_0006335, EFO_0006336
Diseasesleep quality

TRPS1 FBN2 TENM4 OTOG

1.05e-031181114EFO_0005272
DiseaseFamilial thoracic aortic aneurysm and aortic dissection

FBN2 PKD1 NOTCH1

1.06e-03531113C4707243
Diseasexanthine measurement

CNKSR2 EYS

1.06e-03131112EFO_0010548
DiseaseMigraine Disorders

LRP1 NOTCH3

1.06e-03131112C0149931
DiseaseConnective Tissue Diseases

PKD1 NOTCH1

1.06e-03131112C0009782
Diseasegastric ulcer (implicated_via_orthology)

MUC5AC MUC6

1.24e-03141112DOID:10808 (implicated_via_orthology)
Diseaserenal cell carcinoma (is_marker_for)

VWF XIAP TIMP2 TNFRSF1A

1.41e-031281114DOID:4450 (is_marker_for)
Disease16a-hydroxy DHEA 3-sulfate measurement

CYP2C9 GJC3

1.43e-03151112EFO_0800301
Diseaseresponse to antipsychotic drug

EYS TENM4 MEGF10

1.52e-03601113GO_0097332
Diseaseandro steroid monosulfate C19H28O6S (1) measurement

CYP2C9 GJC3

1.63e-03161112EFO_0800305
DiseaseBenign neoplasm of stomach

ERBB3 MET

1.84e-03171112C0153943
DiseaseDementia

GRN NOTCH3

1.84e-03171112C0497327
Diseasethrombomodulin measurement

LAMA1 THBD

1.84e-03171112EFO_0007774
DiseaseNeoplasm of uncertain or unknown behavior of stomach

ERBB3 MET

1.84e-03171112C0496905
DiseaseCarcinoma in situ of stomach

ERBB3 MET

1.84e-03171112C0154060
Diseasedermatomyositis (is_marker_for)

SLIT2 THBD

1.84e-03171112DOID:10223 (is_marker_for)
DiseaseBladder Neoplasm

ERBB3 TIMP2 NOTCH1 NOTCH2

1.96e-031401114C0005695
DiseaseMalignant neoplasm of urinary bladder

ERBB3 TIMP2 NOTCH1 NOTCH2

2.01e-031411114C0005684
Diseaseasthma

CRISPLD2 ERBB3 CRB1 DZANK1 LRP1 SCUBE3 MUC5AC NOTCH4 NSMCE1

2.15e-037511119MONDO_0004979
DiseaseAbdominal Aortic Aneurysm

CRISPLD2 LRP1 PCSK9

2.17e-03681113EFO_0004214
DiseaseMajor Depressive Disorder

ERBB3 CYP2C9 LRP8 NELL1 LRP1

2.29e-032431115C1269683
Diseaseosteochondrodysplasia (is_implicated_in)

MATN3 TRPS1

2.30e-03191112DOID:2256 (is_implicated_in)
Diseasemetabolonic lactone sulfate measurement

CYP2C9 CYP2C18

2.30e-03191112EFO_0800659
Diseasebipolar disorder (is_marker_for)

VWF GRN

2.30e-03191112DOID:3312 (is_marker_for)
Diseasemigraine disorder

TSPAN12 CNKSR2 NELL1 FBN2 LRP1 NOTCH4

2.35e-033571116MONDO_0005277
Diseaseanorexia nervosa

ERBB3 CRB1 LRP2

2.36e-03701113MONDO_0005351
Diseasetaurocholate measurement

CDC42BPA NELL1

2.55e-03201112EFO_0010538
Diseaseunipolar depression, memory performance, cognitive function measurement

TRIM31 TNFRSF13B

2.55e-03201112EFO_0003761, EFO_0004874, EFO_0008354

Protein segments in the cluster

PeptideGeneStartEntry
NHCRSPGQAVCNFVC

MAMDC4

26

Q6UXC1
TKTICAPQCNGHCFG

ERBB3

206

P21860
QHTSCPVGQTCCPSL

GRN

446

P28799
CCFTDFCNNITLHLP

ACVR1C

86

Q8NER5
QTTCCLQPSPSFCLH

DISP1

136

Q96F81
NGALCNPITGACHCA

MEGF10

156

Q96KG7
SNNHTCVPVTQCPCV

MUC6

346

Q6W4X9
GITCHCINGRLSCPQ

MUC6

741

Q6W4X9
VNECLSNPCIHGNCT

NOTCH2

721

Q04721
FVCHTQQPGCKAACF

GJC3

51

Q8NFK1
NECVLSPCRHGASCQ

NOTCH1

871

P46531
QSCFRCAGKSPHNCT

FRAS1

716

Q86XX4
TFCALDPCVLGTHQC

MATN3

261

O15232
SCLNNLCLHQSLCIP

EYS

2936

Q5T1H1
NGHICCSVDPQCLQE

NELL2

801

Q99435
PSVCRHCLCSLTGHQ

ITPRID1

826

Q6ZRS4
HLKICPQGSTCCSQE

GPC4

56

O75487
ANCDIHVCLPSQFKC

LRP1

3406

Q07954
CCLHSLCHPSIVNGI

HERC1

3661

Q15751
NCLPVAHTCFNQLCL

HECTD2

736

Q5U5R9
GAFCVCPLCVTSHLH

GSX2

56

Q9BZM3
CCLLPQANCSVHTAP

PCSK9

526

Q8NBP7
STCNRYQCPAGCLNH

CRISPLD2

301

Q9H0B8
CASQPCQHGGSCIDL

NOTCH3

1126

Q9UM47
CCLDPTSQTNCFHEP

MEGF8

2451

Q7Z7M0
VRCGQAVSVHCSNPC

NFX1

486

Q12986
CECHLQGSVNAFCNP

LAMB1

821

P07942
VSCTPPSCCQLHHAQ

KRTAP1-5

136

Q9BYS1
LCSALNCQYQCHETP

LRP2

311

P98164
CETQICNTHCPVGFE

MUC5AC

5421

P98088
VNSCAVNPCLHNGEC

HEG1

986

Q9ULI3
IVPCSSCLLSCNNGH

FAM72A

86

Q5TYM5
DPFRLQCTCQHNTCG

LAMA5

316

O15230
LCKPNFQGTHCELCA

LAMA5

516

O15230
QCFCKPHVCGQACAS

LAMA5

796

O15230
FACHVSCKDGAPQVC

CDC42BPB

1061

Q9Y5S2
HCSANVTSCLCLGIP

IL9

46

P15248
YITQCPNLNHTCPTC

NELL1

216

Q92832
SHRAGASCVCCSQPQ

NFYC

356

Q13952
CAHQCSNTPGSFKCI

HMCN1

5326

Q96RW7
FFVCTKLHQSPGCCA

PCDHAC1

701

Q9H158
EIHPCPSCCLAFSSQ

PRDM9

386

Q9NQV7
CESGIHNCLPDFICQ

FBLN1

266

P23142
CEKPGISCLTAHCNF

ITGA9

891

Q13797
QCNCTPPTLCTAISH

OTOP1

251

Q7RTM1
GCVQLSNICLSHPCL

CUBN

391

O60494
SNICLSHPCLNGQCI

CUBN

396

O60494
CPLQGSHALCTCCFQ

CHFR

476

Q96EP1
APQQCAVCLQPFCHL

CHFR

506

Q96EP1
FIPCGHLVTCKQCAE

BIRC8

201

Q96P09
CTCHTNCPKNNEAFL

CCN3

331

P48745
QGCLCPCPASFTQSH

DBF4B

441

Q8NFT6
QTGSAHCVVCRAAPC

FSTL3

186

O95633
RHCVATVCGQTCTNP

CRIM1

431

Q9NZV1
QCSLQSEPSGHICGC

CORIN

816

Q9Y5Q5
CFICHRCQQPIGTKS

FHL2

126

Q14192
VQILSGVHNIGICCC

LYST

571

Q99698
AHAVCQNLPGSFQCL

LTBP4

1061

Q8N2S1
NSSSIFCHKCEGLCP

INSRR

311

P14616
CARGHSQEFPTCLQC

LAMB4

1161

A4D0S4
GCAPCNVICSVIFHD

CYP2C18

171

P33260
GCAPCNVICSIIFHK

CYP2C9

171

P11712
PTYCCVCAQHILQGA

DGKE

71

P52429
HASCLNIPGSFKCSC

FBN2

1381

P35556
GCLQLNVCNSNPCLH

CRB1

1136

P82279
CFSNPCIHGNCSDRV

CRB1

1181

P82279
CSVCPKCGASNHLSA

DZANK1

366

Q9NVP4
ICINSPGSFQCLCHR

SCUBE1

336

Q8IWY4
ICVNTPGSFQCLCHR

SCUBE3

331

Q8IX30
FQKEVSSCHCAPCQG

C8B

496

P07358
CNICHSLLIQGQSCE

NSMCE1

191

Q8WV22
PQCFCSNFPHEAVCA

GARNL3

481

Q5VVW2
LCAPHEFQCGNRSCL

LRP8

166

Q14114
LDASCHPQACANGCT

PKD1

656

P98161
FCGPNVINHCFCDLQ

OR4C16

166

Q8NGL9
DLCVPRNQCSCHFQG

OTOG

836

Q6ZRI0
NGLGCRHFQSCSQCL

MET

516

P08581
CLAHSNSCLNPVLYC

RXFP3

376

Q9NSD7
CLAHSNSCLNPVLYC

RXFP4

296

Q8TDU9
TGRCQPCNCHLSGAL

USH2A

996

O75445
PVTIDCGHNFCLKCI

TRIM31

26

Q9BZY9
QSCNDLCEHFCVPNP

THBD

286

P07204
SCCHCALPGENQTVQ

SSPOP

2021

A2VEC9
VFTLDCANQCPHSCA

SSPOP

4676

A2VEC9
PVCTQHCSPLTCAQG

SSPOP

5016

A2VEC9
LPVIHSCQCSSCQGG

SSPOP

5131

A2VEC9
CGCCAAFNNVAITFP

SLC25A51

36

Q9H1U9
LVAPCVPCSCNNHSD

LAMA1

1396

P25391
CCFSSPCSAQVIQIL

PTCH2

566

Q9Y6C5
IICPTGCTCNLHIND

SLITRK3

371

O94933
PILQCQSGHLVCSNC

SIAH1

51

Q8IUQ4
CISQPCLHNGSCQDS

PROZ

91

P22891
CGFSCHITCVNKAPT

CDC42BPA

1046

Q5VT25
CHNTLGSFQCLCPVG

NOTCH4

211

Q99466
CLSQPCHGDAQCSTN

NOTCH4

396

Q99466
CCYLPTRGCLHLCQQ

SPRY3

236

O43610
CACHQLTIQATACTP

SETDB1

741

Q15047
CTHGINSFRCQCPAG

SNED1

326

Q8TER0
GHLNLTAPCNAACSC

SLCO4A1

496

Q96BD0
SGFNHCCLNAPVSAC

CNKSR2

851

Q8WXI2
PVTISCGHNFCLSCI

TRIM61

26

Q5EBN2
GPFQCSICQHLCTDK

TRPS1

1241

Q9UHF7
VFVPCGHLVTCKQCA

XIAP

461

P98170
YNSCAPACQVTCQHP

VWF

1146

P04275
QYCGAACTCHVRNPL

RNF208

241

Q9H0X6
QVPCGHVFCSACLQE

RNF114

41

Q9Y508
CVQPSACPAFLCGVH

SLC5A2

511

P31639
GCCNVLPAFLHCFAT

SLC26A1

381

Q9H2B4
HCSNVCSNDPPCFSV

PXDN

846

Q92626
ACSCSPVHPQQAFCN

TIMP2

26

P16035
TTLHCPTCVALGTCF

TEX101

136

Q9BY14
SNHGTCITGTCICNP

TENM4

636

Q6N022
LHCPAACTCSNNIVD

SLIT2

271

O94813
CCVREFPGCSKQAHQ

TSPAN12

181

O95859
PVSIECGHSFCQECI

TRIM21

26

P19474
PVTINCGHNFCRSCL

TRIM60

26

Q495X7
CNHTLCKPCFQSTVE

RNF168

31

Q8IYW5
NIFTNCCVALCGPIS

ZDHHC14

306

Q8IZN3
CISCASICGQHPKQC

TNFRSF13B

86

O14836
VGTIPEQFSQCCCGH

ULK2

481

Q8IYT8
PVTIDCGHNFCRACL

TRIM10

26

Q9UDY6
GLFVLQSCCNHSCVP

SMYD5

306

Q6GMV2
CSLCLNGTVHLSCQE

TNFRSF1A

146

P19438
FCCGLSLCNQHTIIL

TMEM260

181

Q9NX78
QPCDCQSAGSLHLQC

LAMC3

381

Q9Y6N6