Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionsodium:bicarbonate symporter activity

SLC4A10 SLC4A5

1.03e-046532GO:0008510
GeneOntologyBiologicalProcessregulation of microtubule cytoskeleton organization

MAP2 MAPT ATXN7 MARK2 STIL

8.03e-05176525GO:0070507
GeneOntologyBiologicalProcessnegative regulation of DNA-templated transcription

TRERF1 ZNF512B YEATS2 TRIM66 SP2 TAF3 SALL2 TRO PHF12 TET1 NACA RREB1

1.47e-0413995212GO:0045892
GeneOntologyBiologicalProcesscell morphogenesis

MAP2 MAPT FARP1 SH3D19 TET1 LRP2 MARK2 SLITRK6 PEAK3 RREB1 ULK2

1.57e-0411945211GO:0000902
GeneOntologyBiologicalProcessnegative regulation of RNA biosynthetic process

TRERF1 ZNF512B YEATS2 TRIM66 SP2 TAF3 SALL2 TRO PHF12 TET1 NACA RREB1

1.61e-0414135212GO:1902679
GeneOntologyBiologicalProcessplasma membrane bounded cell projection morphogenesis

MAP2 MAPT FARP1 TET1 LRP2 MARK2 SLITRK6 RREB1 ULK2

1.86e-04819529GO:0120039
GeneOntologyBiologicalProcesscell projection morphogenesis

MAP2 MAPT FARP1 TET1 LRP2 MARK2 SLITRK6 RREB1 ULK2

1.98e-04826529GO:0048858
GeneOntologyBiologicalProcessregulation of microtubule binding

MAP2 MARK2

2.22e-049522GO:1904526
GeneOntologyBiologicalProcessnegative regulation of transcription by RNA polymerase II

ZNF512B YEATS2 SP2 TAF3 SALL2 TRO PHF12 TET1 NACA RREB1

2.57e-0410535210GO:0000122
GeneOntologyCellularComponentCA3 pyramidal cell dendrite

MAP2 SLC4A10

1.89e-053532GO:0097442
GeneOntologyCellularComponentnuclear periphery

MAP2 MAPT ATXN7 POLA1 PAXIP1

7.22e-05171535GO:0034399
GeneOntologyCellularComponentbasal dendrite

MAP2 SLC4A10

2.80e-0410532GO:0097441
DomainTAU_MAP_1

MAP2 MAPT

2.28e-053522PS00229
DomainTAU_MAP_2

MAP2 MAPT

2.28e-053522PS51491
DomainTubulin-binding

MAP2 MAPT

2.28e-053522PF00418
DomainMAP_tubulin-bd_rpt

MAP2 MAPT

2.28e-053522IPR001084
DomainMAP2/MAP4/Tau

MAP2 MAPT

2.28e-053522IPR027324
DomainZnf_C2H2-like

TRERF1 ZNF512B SP2 SALL2 ZFHX4 ATXN7 ZNF621 TSHZ1 ZMAT4 RREB1

5.81e-057965210IPR015880
DomainZnf_C2H2

TRERF1 ZNF512B SP2 SALL2 ZFHX4 ATXN7 ZNF621 TSHZ1 ZMAT4 RREB1

6.39e-058055210IPR007087
DomainZnF_C2H2

TRERF1 ZNF512B SP2 SALL2 ZFHX4 ATXN7 ZNF621 TSHZ1 ZMAT4 RREB1

6.59e-058085210SM00355
DomainNa/HCO3_transpt

SLC4A10 SLC4A5

7.56e-055522IPR003024
DomainANION_EXCHANGER_2

SLC4A10 SLC4A5

1.58e-047522PS00220
DomainANION_EXCHANGER_1

SLC4A10 SLC4A5

1.58e-047522PS00219
DomainPX

SNX14 PIK3C2A SNX21

2.49e-0444523SM00312
DomainBand3_cytoplasmic_dom

SLC4A10 SLC4A5

2.70e-049522IPR013769
DomainBand_3_cyto

SLC4A10 SLC4A5

2.70e-049522PF07565
Domain-

SLC4A10 SLC4A5

2.70e-0495223.40.1100.10
DomainUBA

NACA HUWE1 MARK2

3.03e-0447523PS50030
DomainHCO3_cotransp

SLC4A10 SLC4A5

3.37e-0410522PF00955
DomainHCO3_transpt_C

SLC4A10 SLC4A5

3.37e-0410522IPR011531
DomainPTrfase/Anion_transptr

SLC4A10 SLC4A5

3.37e-0410522IPR016152
DomainHCO3_transpt_euk

SLC4A10 SLC4A5

3.37e-0410522IPR003020
DomainPX

SNX14 PIK3C2A SNX21

3.43e-0449523PF00787
DomainPX

SNX14 PIK3C2A SNX21

3.64e-0450523PS50195
Domain-

SNX14 PIK3C2A SNX21

3.86e-04515233.30.1520.10
DomainPhox

SNX14 PIK3C2A SNX21

4.09e-0452523IPR001683
DomainTIL_dom

ZAN LRP2

6.77e-0414522IPR002919
DomainZinc_finger_PHD-type_CS

TRIM66 TAF3 PHF12

7.87e-0465523IPR019786
DomainPHD

TRIM66 TAF3 PHF12

1.19e-0375523PF00628
DomainZINC_FINGER_C2H2_2

TRERF1 ZNF512B SP2 SALL2 ZFHX4 ZNF621 TSHZ1 RREB1

1.26e-03775528PS50157
DomainZINC_FINGER_C2H2_1

TRERF1 ZNF512B SP2 SALL2 ZFHX4 ZNF621 TSHZ1 RREB1

1.29e-03777528PS00028
DomainZnf_PHD-finger

TRIM66 TAF3 PHF12

1.39e-0379523IPR019787
DomainPHD

TRIM66 TAF3 PHF12

1.95e-0389523SM00249
DomainZnf_PHD

TRIM66 TAF3 PHF12

2.08e-0391523IPR001965
DomainZF_PHD_2

TRIM66 TAF3 PHF12

2.35e-0395523PS50016
DomainZF_PHD_1

TRIM66 TAF3 PHF12

2.42e-0396523PS01359
DomainZnF_U1

ZFHX4 ZMAT4

2.94e-0329522SM00451
DomainZnf_U1

ZFHX4 ZMAT4

2.94e-0329522IPR003604
DomainUBA

HUWE1 MARK2

3.15e-0330522SM00165
DomainUBA

HUWE1 MARK2

4.51e-0336522PF00627
DomainUBA

HUWE1 MARK2

6.67e-0344522IPR015940
DomainZnf_FYVE_PHD

TRIM66 TAF3 PHF12

7.97e-03147523IPR011011
PathwayPID_LKB1_PATHWAY

MAP2 MAPT MARK2

2.70e-0447383M87
PathwayREACTOME_BICARBONATE_TRANSPORTERS

SLC4A10 SLC4A5

3.14e-0410382M27335
PathwayREACTOME_BICARBONATE_TRANSPORTERS

SLC4A10 SLC4A5

3.14e-0410382MM15073
PathwayWP_NEUROGENESIS_REGULATION_IN_THE_OLFACTORY_EPITHELIUM

MAP2 MAPT MARK2

4.78e-0457383M48326
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

TRERF1 YEATS2 TAF3 WAPL MAPT ATXN7 ANLN PHF12 IQCN HUWE1 MARK2 RREB1 PRG4

1.10e-10774531315302935
Pubmed

Interaction network of human early embryonic transcription factors.

TRERF1 ZNF512B TAF3 ZFHX4 SOBP PHF12 TET1 PAXIP1 RREB1

2.94e-0935153938297188
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

TRERF1 YEATS2 SALL2 ZFHX4 PHF12 TET1 LRP2 HUWE1 RREB1

1.33e-0841853934709266
Pubmed

Human transcription factor protein interaction networks.

TRERF1 ZNF512B YEATS2 SP2 TAF3 SALL2 ZFHX4 ATXN7 SOBP PHF12 NACA PAXIP1 LRP2 RREB1

1.96e-081429531435140242
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

ZNF512B YEATS2 TRIM66 TAF3 WAPL SALL2 ZFHX4 MAPT ATXN7 PHF12 LRP2 RREB1

8.90e-081116531231753913
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

TRERF1 ZNF512B WAPL ANLN PHF12 PAXIP1 WAC

1.70e-0726853733640491
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

MAP2 PIK3C2A MAPT ANLN SH3D19 TET1 MARK2 STIL PEAK1 PPIP5K2

6.11e-07861531036931259
Pubmed

Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray.

SP2 WAPL ATXN7 SLC4A10 PPIP5K2 RREB1 WAC

1.50e-0637153715747579
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

YEATS2 TAF3 WAPL ANLN SH3D19 TET1 HUWE1 PEAK1

1.74e-0654953838280479
Pubmed

MAP2 and tau bind longitudinally along the outer ridges of microtubule protofilaments.

MAP2 MAPT

2.28e-06253212082079
Pubmed

Microtubule-associated proteins in mesial temporal lobe epilepsy with and without psychiatric comorbidities and their relation with granular cell layer dispersion.

MAP2 MAPT

2.28e-06253224069608
Pubmed

Microtubule alterations may destabilize photoreceptor integrity: Age-related microtubule changes and pattern of expression of MAP-2, Tau and hyperphosphorylated Tau in aging human photoreceptor cells.

MAP2 MAPT

2.28e-06253232710889
Pubmed

Identification of key amino acids responsible for the distinct aggregation properties of microtubule-associated protein 2 and tau.

MAP2 MAPT

2.28e-06253226134402
Pubmed

Elevated MARK2-dependent phosphorylation of Tau in Alzheimer's disease.

MAPT MARK2

2.28e-06253223001711
Pubmed

Regulation of tubulin, Tau and microtubule associated protein 2 expression during mouse brain development.

MAP2 MAPT

2.28e-0625321303735
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

YEATS2 SP2 ZFHX4 ANLN PAXIP1 TSHZ1 RREB1

2.39e-0639853735016035
Pubmed

Dendritic and axonal distribution of the microtubule-associated proteins MAP2 and tau in the cerebellum of the nervous mutant mouse.

MAP2 MAPT

6.83e-0635323147150
Pubmed

Effects of three microtubule-associated proteins (MAP2, MAP4, and Tau) on microtubules' physical properties and neurite morphology.

MAP2 MAPT

6.83e-06353237258650
Pubmed

Abnormal phosphorylation of tau and the mechanism of Alzheimer neurofibrillary degeneration: sequestration of microtubule-associated proteins 1 and 2 and the disassembly of microtubules by the abnormal tau.

MAP2 MAPT

6.83e-0635328990203
Pubmed

Loss of tau and Fyn reduces compensatory effects of MAP2 for tau and reveals a Fyn-independent effect of tau on calcium.

MAP2 MAPT

6.83e-06353231452242
Pubmed

Participation of structural microtubule-associated proteins (MAPs) in the development of neuronal polarity.

MAP2 MAPT

6.83e-06353211891784
Pubmed

Noncentrosomal microtubules and type II myosins potentiate epidermal cell adhesion and barrier formation.

MAP2 MAPT

6.83e-06353223091070
Pubmed

Mice with targeted Slc4a10 gene disruption have small brain ventricles and show reduced neuronal excitability.

MAP2 SLC4A10

6.83e-06353218165320
Pubmed

Abnormal polarization and axon outgrowth in retinal ganglion cells lacking the POU-domain transcription factor Brn-3b.

MAP2 MAPT

6.83e-06353210924257
Pubmed

Phosphorylation of human Tau protein by microtubule affinity-regulating kinase 2.

MAPT MARK2

1.36e-05453224251416
Pubmed

Phosphorylation of MAP2c and MAP4 by MARK kinases leads to the destabilization of microtubules in cells.

MAP2 MARK2

1.36e-05453210542369
Pubmed

The protein phosphatase PP2A/Bα binds to the microtubule-associated proteins Tau and MAP2 at a motif also recognized by the kinase Fyn: implications for tauopathies.

MAP2 MAPT

1.36e-05453222403409
Pubmed

Phosphorylation of microtubule-associated proteins MAP2 and MAP4 by the protein kinase p110mark. Phosphorylation sites and regulation of microtubule dynamics.

MAP2 MAPT

1.36e-0545328631898
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ZNF512B WAPL PHF12 TET1 NACA MTSS1 PPIP5K2

1.52e-0552953714621295
Pubmed

The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation.

SALL2 PIK3C2A MAPT POLA1 SH3D19 NACA MARK2 PEAK1 WAC

1.95e-05100753934597346
Pubmed

Midbody and primary cilium of neural progenitors release extracellular membrane particles enriched in the stem cell marker prominin-1.

ANLN LRP2

2.27e-05553217283184
Pubmed

The Phox homology (PX) domain, a new player in phosphoinositide signalling.

SNX14 SNX21

2.27e-05553211736640
Pubmed

Regulation of phosphorylation of neuronal microtubule-associated proteins MAP1b and MAP2 by protein phosphatase-2A and -2B in rat brain.

MAP2 MAPT

2.27e-05553210640627
Pubmed

FKBP51 modulates hippocampal size and function in post-translational regulation of Parkin.

MAP2 MAPT

2.27e-05553235244772
Pubmed

c-Src regulates δ-secretase activation and truncated Tau production by phosphorylating the E3 ligase Traf6.

MAP2 MAPT

2.27e-05553237977223
Pubmed

Akt and CHIP coregulate tau degradation through coordinated interactions.

MAPT MARK2

2.27e-05553218292230
Pubmed

Differential expression of CRMP1, CRMP2A, CRMP2B, and CRMP5 in axons or dendrites of distinct neurons in the mouse brain.

MAP2 MAPT

2.27e-05553215834957
Pubmed

Comprehensive identification of phosphorylation sites in postsynaptic density preparations.

MAP2 MAPT SLC4A10 MARK2 PEAK1

2.74e-0523153516452087
Pubmed

The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.

TRERF1 YEATS2 SALL2 NACA PAXIP1 HUWE1

3.07e-0539653626687479
Pubmed

Roles of tau protein in health and disease.

MAP2 MAPT MARK2

3.17e-054053328386764
Pubmed

Role of individual MARK isoforms in phosphorylation of tau at Ser²⁶² in Alzheimer's disease.

MAPT MARK2

3.40e-05653223666762
Pubmed

Phosphoproteomic analysis of the developing mouse brain.

WAPL MAP2 MAPT NACA HUWE1

3.70e-0524653515345747
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

ZNF512B TAF3 WAPL ANLN POLA1 PHF12 RREB1

3.70e-0560853736089195
Pubmed

Quantitative interaction proteomics and genome-wide profiling of epigenetic histone marks and their readers.

YEATS2 TAF3 ATXN7 PHF12

3.94e-0512453420850016
Pubmed

The distribution and characterization of endogenous protein arginine N-methyltransferase 8 in mouse CNS.

MAP2 MAPT

4.76e-05753219576965
Pubmed

Perinatal lethality of microtubule-associated protein 1B-deficient mice expressing alternative isoforms of the protein at low levels.

MAP2 MAPT

6.34e-05853211085878
Pubmed

Defects in Synaptic Plasticity, Reduced NMDA-Receptor Transport, and Instability of Postsynaptic Density Proteins in Mice Lacking Microtubule-Associated Protein 1A.

MAP2 MAPT

6.34e-05853226609151
Pubmed

Temporal and spatial expression profiles of the Fat3 protein, a giant cadherin molecule, during mouse development.

MAP2 MAPT

6.34e-05853217131403
Pubmed

The Human Tau Interactome: Binding to the Ribonucleoproteome, and Impaired Binding of the Proline-to-Leucine Mutant at Position 301 (P301L) to Chaperones and the Proteasome.

MAP2 MAPT MARK2

6.61e-055153326269332
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

YEATS2 SLC9A8 MAP2 MAPT ATXN7 SOBP FARP1 IQCN HUWE1 SLC4A5

7.28e-051489531028611215
Pubmed

The functional interactome landscape of the human histone deacetylase family.

TRERF1 ZNF512B PHF12 HUWE1 RREB1

7.92e-0528953523752268
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

YEATS2 WAPL ANLN NACA HUWE1 PPIP5K2 RREB1

1.19e-0473353734672954
Pubmed

Expression QTL and regulatory network analysis of microtubule-associated protein tau gene.

MAPT ATXN7

1.24e-041153219233709
Pubmed

Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.

WAPL MAP2 PAXIP1 MARK2 PEAK1

1.31e-0432253526514267
Pubmed

CAMSAP1 breaks the homeostatic microtubule network to instruct neuronal polarity.

MAP2 MAPT

1.49e-041253232839317
Pubmed

Severe neurologic impairment in mice with targeted disruption of the electrogenic sodium bicarbonate cotransporter NBCe2 (Slc4a5 gene).

SLC4A10 SLC4A5

1.49e-041253221705333
Pubmed

Abeta-degrading endopeptidase, neprilysin, in mouse brain: synaptic and axonal localization inversely correlating with Abeta pathology.

MAP2 MAPT

1.49e-041253212074840
Pubmed

Distinct PEAK3 interactors and outputs expand the signaling potential of the PEAK pseudokinase family.

PEAK1 PEAK3

1.49e-041253235192416
Pubmed

COUP-TFI is required for the formation of commissural projections in the forebrain by regulating axonal growth.

MAP2 MAPT

1.49e-041253217021036
Pubmed

Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.

WAPL ANLN POLA1 HUWE1 RREB1

1.52e-0433253532786267
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

MAP2 PIK3C2A MAPT SLC4A10 MARK2

1.86e-0434753517114649
Pubmed

The c-Jun N-terminal kinase activator dual leucine zipper kinase regulates axon growth and neuronal migration in the developing cerebral cortex.

MAP2 MAPT

2.05e-041453217108173
Pubmed

Stage-specific association of apolipoprotein A-I and E in developing mouse retina.

MAP2 LRP2

2.05e-041453217389516
Pubmed

Essential role of Rac1 and Rac3 GTPases in neuronal development.

MAP2 MAPT

2.05e-041453219126596
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

WAPL ANLN FARP1 TET1 LRP2 HUWE1 PEAK1 ULK2

2.22e-04108453811544199
Pubmed

C3G/Rapgef1 Is Required in Multipolar Neurons for the Transition to a Bipolar Morphology during Cortical Development.

MAP2 MAPT

2.36e-041553227111087
Pubmed

The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.

ZFHX4 FARP1 PHF12 PAXIP1 HUWE1 RREB1

2.54e-0458353629844126
Pubmed

MARK4 is a novel microtubule-associated proteins/microtubule affinity-regulating kinase that binds to the cellular microtubule network and to centrosomes.

MAP2 MAPT

2.70e-041653214594945
Pubmed

A large family of endosome-localized proteins related to sorting nexin 1.

SNX14 SNX21

3.05e-041753211485546
Pubmed

Sorting out the cellular functions of sorting nexins.

SNX14 SNX21

3.05e-041753212461558
Pubmed

Phosphoproteomic analysis of synaptosomes from human cerebral cortex.

MAP2 MAPT

3.05e-041753215822905
Pubmed

Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.

ZNF512B YEATS2 ATXN7 PAXIP1

3.70e-0422253437071664
Pubmed

LKB1 and SAD kinases define a pathway required for the polarization of cortical neurons.

MAP2 MAPT

3.83e-041953217482548
Pubmed

Teashirt 1 (Tshz1) is essential for the development, survival and function of hypoglossal and phrenic motor neurons in mouse.

MAPT TSHZ1

3.83e-041953231427287
Pubmed

Molecular characterization of mutant mouse strains generated from the EUCOMM/KOMP-CSD ES cell resource.

TRIM66 MAP2

3.83e-041953223912999
Pubmed

A census of human transcription factors: function, expression and evolution.

TRERF1 YEATS2 SP2 SALL2 ZFHX4 TSHZ1 RREB1

4.38e-0490853719274049
Pubmed

KIF2A deficiency causes early-onset neurodegeneration.

MAP2 MAPT

4.70e-042153236343267
Pubmed

The N-Myc-DLL3 cascade is suppressed by the ubiquitin ligase Huwe1 to inhibit proliferation and promote neurogenesis in the developing brain.

MAP2 HUWE1

4.70e-042153219686682
Pubmed

Dlx transcription factors promote migration through repression of axon and dendrite growth.

MAP2 MAPT

4.70e-042153217582329
Pubmed

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

TRIM66 SALL2 HUWE1

5.46e-041045339205841
Pubmed

Genetic Labeling of Nuclei-Specific Thalamocortical Neurons Reveals Putative Sensory-Modality Specific Genes.

ZFHX4 TSHZ1

5.65e-042353227655933
Pubmed

Characterization of MRFAP1 turnover and interactions downstream of the NEDD8 pathway.

PHF12 HUWE1

5.65e-042353222038470
Pubmed

Identification of proximal SUMO-dependent interactors using SUMO-ID.

YEATS2 SP2 SALL2 ATXN7 ANLN

5.75e-0444453534795231
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

ZNF512B YEATS2 TAF3 WAPL ANLN RREB1 WAC

5.87e-0495453736373674
Pubmed

Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System.

ZFHX4 PTPRN TSHZ1 SLITRK6

5.88e-0425153429031500
Pubmed

ATAC and Mediator coactivators form a stable complex and regulate a set of non-coding RNA genes.

YEATS2 ATXN7 MARK2

5.93e-0410753320508642
Pubmed

Genomic screen for genes involved in mammalian craniofacial development.

TRO PAXIP1

6.16e-042453212533789
Pubmed

Rheb1 is required for mTORC1 and myelination in postnatal brain development.

MAP2 MAPT

6.68e-042553221238928
Pubmed

MCM8IP activates the MCM8-9 helicase to promote DNA synthesis and homologous recombination upon DNA damage.

SALL2 RREB1

6.68e-042553232528060
Pubmed

Regulation of differentiation flux by Notch signalling influences the number of dopaminergic neurons in the adult brain.

MAP2 MAPT

7.23e-042653226912775
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

YEATS2 SP2 TAF3 WAPL NACA HUWE1 PPIP5K2 RREB1

8.10e-04131853830463901
Pubmed

The protein kinase complement of the human genome.

PEAK1 ULK2

8.40e-042853212471243
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

SNX14 TAF3 POLA1 PHF12 PAXIP1 SNAPC2 ULK2 WAC

8.46e-04132753832694731
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

TRIM66 SP2 SLC9A8 PEAK1 WAC

9.19e-0449353515368895
Pubmed

A High-Density Map for Navigating the Human Polycomb Complexome.

ZNF512B YEATS2 TET1 PAXIP1 RREB1

9.36e-0449553527705803
Pubmed

A chromatin modulator sustains self-renewal and enables differentiation of postnatal neural stem and progenitor cells.

MAP2 PTPRN

9.64e-043053231065682
Pubmed

HIV-1 Vpr degrades the HLTF DNA translocase in T cells and macrophages.

ANLN POLA1

1.10e-033253227114546
Pubmed

Single-cell transcriptomic analysis reveals diversity within mammalian spinal motor neurons.

ZFHX4 MAPT

1.10e-033253236596814
Pubmed

The role of primary cilia in corpus callosum formation is mediated by production of the Gli3 repressor.

MAP2 MAPT

1.17e-033353226071364
Pubmed

Transcriptome of the inner circular smooth muscle of the developing mouse intestine: Evidence for regulation of visceral smooth muscle genes by the hedgehog target gene, cJun.

SALL2 MAPT TSHZ1

1.29e-0314053326930384
InteractionBAG2 interactions

YEATS2 TRIM66 SALL2 PIK3C2A MAPT ANLN PHF12 HUWE1 STIL PPIP5K2 RREB1

4.24e-076225211int:BAG2
InteractionFEV interactions

ZNF512B SP2 TAF3 ZFHX4 PHF12 PAXIP1 RREB1

8.65e-07203527int:FEV
InteractionCDC16 interactions

YEATS2 TAF3 SALL2 PIK3C2A ANLN PAXIP1 STIL

3.11e-06246527int:CDC16
InteractionEGR2 interactions

TRERF1 ZFHX4 PHF12 TET1 PAXIP1 RREB1

5.04e-06171526int:EGR2
InteractionELK3 interactions

SP2 TAF3 ZFHX4 PHF12 RREB1

1.43e-05120525int:ELK3
InteractionKDM1A interactions

TRERF1 YEATS2 SALL2 ZFHX4 MAPT PHF12 SH3D19 TET1 LRP2 HUWE1 RREB1

2.25e-059415211int:KDM1A
InteractionRHOT1 interactions

TRIM66 MAPT ANLN HUWE1

2.68e-0567524int:RHOT1
InteractionPHF21A interactions

YEATS2 SALL2 ZFHX4 PHF12 TET1 HUWE1 RREB1

2.70e-05343527int:PHF21A
InteractionNMNAT2 interactions

YEATS2 SALL2 MAPT

3.58e-0525523int:NMNAT2
InteractionRCOR1 interactions

YEATS2 TRIM66 SALL2 ZFHX4 PHF12 TET1 HUWE1 RREB1

3.59e-05494528int:RCOR1
InteractionGUSBP5 interactions

ZFHX4 PIK3C2A PHF12 STIL

4.18e-0575524int:GUSBP5
InteractionRBBP7 interactions

ZNF512B SALL2 MAPT ANLN PHF12 TET1 PAXIP1 HUWE1

4.32e-05507528int:RBBP7
InteractionTBP interactions

YEATS2 TAF3 ATXN7 NACA SNAPC2 HUWE1

4.63e-05253526int:TBP
InteractionCRX interactions

TRERF1 ZNF512B ZFHX4 ATXN7 PAXIP1 RREB1

4.73e-05254526int:CRX
InteractionMARK4 interactions

TRIM66 MAP2 MAPT MARK2

6.23e-0583524int:MARK4
InteractionHNF4A interactions

YEATS2 TAF3 ATXN7 PHF12 PAXIP1 RREB1

7.35e-05275526int:HNF4A
InteractionYWHAH interactions

MAP2 PIK3C2A MAPT ANLN SH3D19 TET1 HUWE1 MARK2 STIL PEAK1 PPIP5K2

9.48e-0511025211int:YWHAH
InteractionABCG2 interactions

ANLN PHF12 HUWE1

1.09e-0436523int:ABCG2
InteractionSUMO2 interactions

WAPL ATXN7 ANLN SOBP POLA1 NACA HUWE1 RREB1

1.26e-04591528int:SUMO2
InteractionWDR6 interactions

TRIM66 ANLN POLA1 FARP1 MARK2 PPIP5K2

1.52e-04314526int:WDR6
InteractionRAB3D interactions

MAPT ATXN7 ANLN

1.61e-0441523int:RAB3D
InteractionSMG7 interactions

YEATS2 TRIM66 SALL2 TET1 PAXIP1 STIL

1.66e-04319526int:SMG7
InteractionMAGEA9 interactions

TAF3 SALL2 ZFHX4 PIK3C2A STIL

1.96e-04208525int:MAGEA9
InteractionCCNJL interactions

SALL2 PIK3C2A STIL

2.13e-0445523int:CCNJL
InteractionNANOG interactions

TRERF1 YEATS2 WAPL SALL2 TET1 PAXIP1 HUWE1

2.23e-04481527int:NANOG
InteractionCBX3 interactions

ZNF512B YEATS2 TRIM66 WAPL MAPT ANLN RREB1 WAC

2.31e-04646528int:CBX3
InteractionRPTOR interactions

ZNF512B TRIM66 NACA SNX21 HUWE1 ULK2

2.37e-04341526int:RPTOR
InteractionDCTN1 interactions

ZNF512B MAP2 MAPT SH3D19 NACA HUWE1 MARK2

2.72e-04497527int:DCTN1
InteractionPOLR1E interactions

ZNF512B SALL2 ANLN TET1 PAXIP1 RREB1

2.73e-04350526int:POLR1E
InteractionYWHAG interactions

MAP2 PIK3C2A MAPT ANLN SH3D19 TET1 HUWE1 MARK2 PEAK1 PPIP5K2 GAREM1

2.82e-0412485211int:YWHAG
InteractionCRKL interactions

HUWE1 PEAK1 PEAK3 WAC GAREM1

2.93e-04227525int:CRKL
InteractionGTPBP1 interactions

PIK3C2A MAPT ANLN STIL

2.94e-04124524int:GTPBP1
InteractionLZTS2 interactions

ZNF512B TRIM66 PIK3C2A ANLN IQCN HUWE1 STIL

3.26e-04512527int:LZTS2
InteractionPAX6 interactions

ZNF512B TAF3 ZFHX4 PHF12 PAXIP1 RREB1

3.47e-04366526int:PAX6
InteractionFKBP3 interactions

MAPT ANLN NACA GAREM1

3.63e-04131524int:FKBP3
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZFHX4 TSHZ1

3.55e-0415342529
GeneFamilyPHD finger proteins

TRIM66 TAF3 PHF12

6.38e-049034388
GeneFamilySorting nexins|PX-BAR domain containing

SNX14 SNX21

1.35e-0329342754
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

SP2 SALL2 ZNF621 TSHZ1 RREB1

1.04e-0271834528
CoexpressionMURARO_PANCREAS_BETA_CELL

MAP2 PIK3C2A PTPRN MAPT SOBP MTSS1 SLC4A10 TSHZ1 HUWE1 WAC

1.43e-059465210M39169
CoexpressionAtlasFacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_1000

TAF3 WAPL GARNL3 ZFHX4 SOBP TSHZ1 ZMAT4 STIL PEAK1 SLITRK6 PPIP5K2

1.09e-059784911Facebase_RNAseq_e10.5_Mandibular Arch_1000
CoexpressionAtlasfacebase_RNAseq_e14.5_palate_poster_proximal_ERK2_WT_2500_K2

TRERF1 GARNL3 MAP2 TET1 MTSS1 SNX21 SNAPC2 MARK2 PEAK1 SLITRK6 ULK2 WAC

1.41e-0512084912facebase_RNAseq_e14.5_palate_poster_proximal_ERK2_WT_2500_K2
CoexpressionAtlasFacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_1000_k-means-cluster#3

TAF3 ZFHX4 TRO TET1 PEAK1 SLITRK6 WAC

5.65e-05432497Facebase_RNAseq_e10.5_Maxillary Arch_1000_K3
CoexpressionAtlasdev gonad_e12.5_F_VasAssMesen_MafB_k-means-cluster#4_top-relative-expression-ranked_1000

YEATS2 ZFHX4 MAP2 TSHZ1 PEAK1 PPIP5K2

6.47e-05301496gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_k4_1000
CoexpressionAtlasdev gonad_e12.5_F_VasAssMesen_MafB_top-relative-expression-ranked_1000

YEATS2 ZFHX4 MAP2 SOBP POLA1 FARP1 TSHZ1 PEAK1 PPIP5K2

6.58e-05783499gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_500

TAF3 WAPL SOBP TSHZ1 ZMAT4 SLITRK6 PPIP5K2

1.27e-04492497Facebase_RNAseq_e10.5_Mandibular Arch_500
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ZAN MAPT SLC4A10 LRP2 ZMAT4

1.50e-061675253edb0570e583bb527165bcd8a4c25a042054043b
ToppCelldroplet-Heart-nan-3m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRERF1 ZFHX4 MAP2 ANLN SLITRK6

2.16e-06180525da723df348d7b8449bb1124f23fe6fa706412adb
ToppCelldroplet-Heart-nan-3m-Neuronal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRERF1 ZFHX4 MAP2 ANLN SLITRK6

2.16e-061805255b146a94708b3c3610542a4d0925f3f7a2b19185
ToppCelldroplet-Heart-nan-3m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRERF1 ZFHX4 MAP2 ANLN SLITRK6

2.16e-0618052550758b1e7be2e43f83c10ab106900c067e61f5f7
ToppCellControl-Neu_4|World / 5 Neutrophil clusters in COVID-19 patients

TRERF1 WAPL PIK3C2A ATXN7 ANLN

2.41e-06184525ce7f044956613118ee2e9fb6af2455c3166cb414
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM66 MAP2 SOBP ZMAT4

3.74e-0516152469f5e759c0925daa37e0177a9cc3154842906bf6
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SALL2 ANLN POLA1 STIL

4.84e-051725242b6cd84c946b1e800caba452ae70145ea285fec1
ToppCellwk_08-11-Mesenchymal-Fibroblast-Mesenchymal_2|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

MXRA5 ZFHX4 ZMAT4 SLITRK6

5.90e-051815249b2d207dc9fc2228a1555ed360286bb7c2d988ff
ToppCelldroplet-Lung-nan-3m-Epithelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZFHX4 LRP2 SLC4A5 GAREM1

6.03e-05182524cfba75c1ffc39ac76db9e8e27394731942882b30
ToppCelldroplet-Lung-nan-3m-Epithelial-type_II_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZFHX4 LRP2 SLC4A5 GAREM1

6.03e-051825247e7c7a26460d3003cdf0c0ffb96208a566aa09a7
ToppCelldroplet-Lung-nan-3m-Epithelial-Alveolar_Epithelial_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZFHX4 LRP2 SLC4A5 GAREM1

6.03e-05182524d836bfdc298ecd3558a973e393a329eb8bd59d79
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TRERF1 ZFHX4 TSHZ1 SLITRK6

6.16e-0518352412daaea821e49bc94a01e2496331e92a80d27339
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANLN POLA1 ZMAT4 STIL

6.29e-0518452416aa8e88bdd51b1d132d5cf33c29963b384a8bae
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MAPT SOBP LRP2 RREB1

6.56e-051865245784d255e9ca449d375d81938d0fbbd8a7eb44f6
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MAPT SOBP LRP2 RREB1

6.69e-051875243ae3b8de1a195d4d5057cf3c64fcdb5f48681ce5
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZFHX4 ANLN LRP2 RREB1

6.98e-0518952442ab4cc5fbf8580841f31889446fe4499df1a464
ToppCellASK428-Epithelial-Transformed_epithelium|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

MXRA5 ZFHX4 TRO PRG4

6.98e-0518952487189275234b5d59484c58acbb14a09903f2b578
ToppCellTracheal-NucSeq-Stromal-Peri/Epineurial_-NAF_endoneurial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ZFHX4 MTSS1 ZMAT4 PRG4

7.56e-05193524549a0b750c860b615aff767ad04c9a9d20f802f0
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FARP1 SH3D19 LRP2 GAREM1

7.72e-051945247002937e8903e037332a215d00fbc7c7843b33f2
ToppCellASK428-Epithelial-Transformed_epithelium|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

MXRA5 ZFHX4 TRO PRG4

7.87e-05195524c750602c765a51075ba6ede78e3ba80b62374481
ToppCellfacs-Thymus-nan-3m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANLN POLA1 PAXIP1 STIL

7.87e-0519552493c345e70d6c8ff5d12fd63d73228c1700b804a0
ToppCellfrontal_cortex-Neuronal|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PTPRN MAPT TRO SLC4A10

8.03e-05196524de7d10da862f98894ce47244fbc992f4a12d63bb
ToppCell3'-GW_trimst-1-SmallIntestine-Neuronal-neurons_A-Branch_A2_(IPAN/IN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GARNL3 MAP2 PTPRN MAPT

8.19e-05197524f7eaac1c321710a55e09ffb047a7db2baf7b7e28
ToppCellFibroblasts-DKK3+_Fibroblasts|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

MXRA5 ZFHX4 SOBP SH3D19

8.35e-051985244f4632f26a2043c5e4ab89031b4229b5dca1bd48
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal-6|World / Primary Cells by Cluster

MAP2 MAPT ANLN NACA

8.51e-051995241b1bccf4293f11048709d15a3c892c0edf3da3d2
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal|World / Primary Cells by Cluster

MAP2 MAPT ANLN NACA

8.51e-051995244bee94c116c0da5eba951cb4cea7cc9dcdd6e30f
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Neuronal-Cortical_neuron|10w / Sample Type, Dataset, Time_group, and Cell type.

ZFHX4 MAP2 MAPT SOBP

8.68e-0520052468c90376e2779434e4ad8dc6dd3b44baa700e2f4
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Neuronal|10w / Sample Type, Dataset, Time_group, and Cell type.

ZFHX4 MAP2 MAPT SOBP

8.68e-05200524979258173b82f37aeaaedd53b4a527da1dbe1b80
ToppCellControl_saline-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|Control_saline / Treatment groups by lineage, cell group, cell type

TRERF1 ZFHX4 TSHZ1 SLITRK6

8.68e-05200524a799fc7bb83ad0524362cb5010df949741fb7bf3
ToppCellBrain_organoid-organoid_Tanaka_cellReport-5w-Neuronal-Intermediate|5w / Sample Type, Dataset, Time_group, and Cell type.

ZFHX4 MAPT SOBP WAC

8.68e-05200524c92e4fc0442404481fcac623d691dae6215b852d
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Neuronal-Interneuron|10w / Sample Type, Dataset, Time_group, and Cell type.

ZFHX4 MAP2 MAPT MTSS1

8.68e-05200524f5c63ef52bd7a898cf009b8bf9b2f7f4890d1c9b
ToppCellBiopsy_Control_(H.)-Mesenchymal-PLIN2+_Fibroblasts|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

MXRA5 ZFHX4 TET1 PRG4

8.68e-05200524cdaf462b1db29dab61038eeab5ddd3eef3386763
ToppCelldroplet-Lung-30m-Hematologic-myeloid-interstitial_macrophage-interstitial_macrophage_l14|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MAPT STIL PRG4

2.58e-04106523ede8407ad253080d1fa2a6e2aacf549ce220309a
ToppCellTCGA-Thymus-Primary_Tumor-Thymoma-Type_B2-7|TCGA-Thymus / Sample_Type by Project: Shred V9

MAP2 ZMAT4 SLITRK6

3.37e-04116523de4c3700e6b2f79583f74262df2380714ce9cd6b
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Neuronal-Interneuron|GW19 / Sample Type, Dataset, Time_group, and Cell type.

TRERF1 STIL PRG4

3.81e-04121523b2d571f571133c281d72584fe925cebbd2317829
ToppCellCOVID-19_Mild-Neu_1|World / 5 Neutrophil clusters in COVID-19 patients

WAPL MAPT LRP2

4.19e-04125523e58c208b4355252ceabe04a468dd19a1f436182c
ToppCellLPS-IL1RA+antiTNF-Unknown-Endothelial-Pericyte_2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SALL2 MAPT ANLN

5.71e-041395232fb51abb3ce88c21726c026d6365b2582e2e79f6
ToppCellMild/Remission-B_naive-5|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

MAP2 SOBP IQCN

6.07e-04142523fc5fc2d2b4b976358b8ce762c1f440b20db84103
ToppCellNS-critical-d_0-4-Myeloid-pDC|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

GARNL3 POLA1 PRG4

6.33e-041445230fde5cd82df9b90aefde19275cff6c2ec3c9d5cb
ToppCell343B-Lymphocytic-CD8+_Cytotoxic_T-cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

GARNL3 FARP1 SLC4A10

6.58e-04146523bb7bf20245d93c8812920dd0debbf1ed00add378
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Ntn1_Npy2r|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ZAN TSHZ1 ZMAT4

6.85e-041485235e738522d4ad35e08bc4ff8c41b7bea38ec6ef95
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRERF1 SOBP PRG4

7.12e-041505231270f33f9d7e46e55adf1a96e8beee858b95589d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-high_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRERF1 SOBP PRG4

7.12e-04150523156118ce1d69522624196410cba18b8354cd0bb4
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-14|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SOBP MTSS1 SLC4A5

7.12e-041505234bdcdce40f54580c7a4e1416b468e657ba8874fc
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Ntn1_Npy2r|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ZAN TSHZ1 ZMAT4

7.40e-041525238ff5a178a8f3550d89a003c0858820aab3773386
ToppCellPBMC-Mild-Lymphocyte-B-B_cell-B_naive-B_naive-5|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MAP2 SOBP IQCN

7.69e-04154523020697ae8463b18f9b4270c404f52ce4c0e90135
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

POLA1 PAXIP1 PRG4

8.13e-04157523eea53cf8d8a607264e1ee00b7a97c94bcf2ac80d
ToppCell343B-Lymphocytic-NK_cells-NK_cell_D2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

FARP1 STIL SLITRK6

8.28e-0415852374aa4f75307575ac3b2b1aa9f727753692f88742
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

POLA1 PAXIP1 PRG4

8.43e-0415952395128a2367ff2a639b21913c0350924c174faef8
ToppCell3'-Adult-Distal_Rectal-Epithelial-goblet-BEST2+_Goblet_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IQCN SLITRK6 GAREM1

8.43e-041595236ec5489d55667e53bd9c021ada7de458bfef43a3
ToppCell356C-Fibroblasts-Fibroblast-G-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

MAPT MTSS1 PEAK1

8.58e-041605230293b244c063a62819690bf22bbc2681f8d15252
ToppCell356C-Fibroblasts-Fibroblast-G|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

MAPT MTSS1 PEAK1

8.58e-041605233eaae86fa08f7651021316f8e5811bf48055591e
ToppCell343B-Lymphocytic-NK_cells-NK_cell_D2|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

FARP1 STIL SLITRK6

8.74e-0416152358381131e651744b5141b202f9d6063f55432db5
ToppCellVE-CD8-CD4_Treg|VE / Condition, Cell_class and T cell subcluster

ZNF512B MTSS1 SLC4A10

8.74e-04161523a114f4f75859d9ef900e5146686438d051241429
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MAP2 IQCN GAREM1

8.90e-04162523373513f9d0e5007b2e10a8b78d4909dcce9e3b62
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP2 SOBP ZMAT4

9.38e-0416552302cd87dfa2ca40e13455a4b9308477e82f76289b
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP2 SOBP ZMAT4

9.38e-041655236d8b5669eee9b0903c9260fea707d186c9d7fefa
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

POLA1 LRP2 ZMAT4

9.55e-04166523575c325db88d6909cdf0d5e664bd9098b89d4401
ToppCell367C-Fibroblasts-Fibroblast-F-|367C / Donor, Lineage, Cell class and subclass (all cells)

MXRA5 ANLN PRG4

9.55e-041665231cc291a04f4144abba4aca7badeb7776db05d903
ToppCell367C-Fibroblasts-Fibroblast-F|367C / Donor, Lineage, Cell class and subclass (all cells)

MXRA5 ANLN PRG4

9.55e-041665232887f4f0c218cbcbcc82eef27aa4ee714b35cddb
ToppCellfacs-Spleen-nan-18m-Hematologic-proerythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOBP SNX21 STIL

9.55e-041665238d535fab019356894b4dad3fbdbc4d2ad3e16082
ToppCellfacs-Spleen-nan-18m-Hematologic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOBP SNX21 STIL

9.55e-04166523f56b1c0d6cb5353a16a2598bda905287f16d2c39
ToppCellfacs-Spleen-nan-18m-Hematologic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOBP SNX21 STIL

9.55e-04166523a5074c96c6561273029aceb93402a7e038140f50
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ANLN POLA1 STIL

9.71e-04167523108ae6221c6edc63c0ec42c42471b3a15a594043
ToppCelldroplet-Kidney-nan-18m-Epithelial-Epcam____brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC9A8 LRP2 SLITRK6

9.71e-04167523ed7e785dcd25777f64e0c2596ada4f5a5ea17121
ToppCell368C-Fibroblasts-Fibroblast-C_(Myofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

TRERF1 POLA1 ULK2

9.88e-04168523c66a61d3ec711796313a2c6d2dc39aedbfc20afd
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRERF1 SOBP PRG4

9.88e-04168523d19a115365c5415e51c039718d7669de788fcf33
ToppCell368C-Fibroblasts-Fibroblast-C_(Myofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

TRERF1 POLA1 ULK2

9.88e-0416852383b4f817d95daa15ae60668e789f97d8a3b2e6dd
ToppCellTCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-4|TCGA-Liver / Sample_Type by Project: Shred V9

SALL2 SOBP TET1

1.01e-031695230a3ba6b5d6cff9d3d7f56046063cfc3a37ae1156
ToppCellControl-T/NK_proliferative|World / Disease group and Cell class

ANLN STIL PEAK1

1.01e-03169523fca735cbb55fce4d32dc6632a39acea1d16b87ab
ToppCelldroplet-Kidney-nan-18m-Epithelial-brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC9A8 LRP2 SLITRK6

1.01e-03169523f00741203efa0b948db7223ee8c19bdd0918258a
ToppCellfacs-Marrow-KLS-24m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRERF1 GARNL3 SNX21

1.01e-03169523d6ad3b637de2935c656aad47ad82d6e8a8bd1227
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ANLN POLA1 STIL

1.01e-031695230bc8ef341ce307b19018d4ac8de0a4d04254209d
ToppCell5'-Adult-SmallIntestine-Hematopoietic-B_cells-Cycling_B_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ANLN SOBP STIL

1.01e-03169523a34aff9257ae9746226ee7af595c4678a4b0c896
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ANLN POLA1 STIL

1.01e-03169523e7514956b2e4298222ec443f98b2f5289451786e
ToppCellfacs-Marrow-KLS-24m-Myeloid-monocyte_+_promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRERF1 GARNL3 SNX21

1.01e-0316952360ef186518d0dc63dbded2a77c65cfe3129df754
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

PTPRN ANLN SLC4A10

1.01e-0316952396a2aec9acf8a6f966973c035e5ade456cf47772
ToppCellNS-critical-LOC-Epithelial-FOXN4+|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MXRA5 ANLN STIL

1.02e-03170523f6a0162bb690dbc19ff1cec64cb933744ad3b496
ToppCell390C-Lymphocytic-NK_cells-Proliferating_NK_cell|390C / Donor, Lineage, Cell class and subclass (all cells)

TRIM66 PAXIP1 STIL

1.02e-031705235319f73cff64f2bb67472c7156ee1d0f006c6fc0
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ANLN ZMAT4 STIL

1.04e-03171523c2dbc439af28d4fabb24d57685b75b2e588819b0
ToppCell367C-Myeloid-Dendritic-cDC_proliferating_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

ANLN ZNF621 GAREM1

1.04e-031715230eea035fde32cc2a75a0d4227911edb5d54ed47e
ToppCellfacs-Marrow-KLS-18m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRERF1 MAPT ANLN

1.09e-031745239d5dcd46cf346c381dea68ada6665f7fb68114a3
ToppCellfacs-Marrow-KLS-18m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRERF1 MAPT ANLN

1.09e-0317452353cec5c666c45278a71c21dd9c62a052a97e0fdf
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ANLN POLA1 STIL

1.09e-031745236c36d607c48267a75ab4da6fb2fe3f931d1b3b52
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_G2M|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MAP2 ANLN TRO

1.09e-0317452341eb0a214a8b4015a26311f77061c8147144f0e7
ToppCell10x_5'_v1-Neoplastic-Stem-like-OPC-like|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MAP2 ANLN ULK2

1.11e-03175523cc596907ea1a64ab7b5a8c7d4ad12e6ee59bfed9
ToppCellRSV-Healthy-2|Healthy / Virus stimulation, Condition and Cluster

ANLN SOBP TET1

1.11e-03175523c47440c0b0513e67fe13b85f10dd8a8d42d0e9a3
ToppCell10x_5'_v1-Neoplastic-Stem-like|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MAP2 ANLN ULK2

1.11e-03175523a8400e7e47379901dcab5f2e364c3ff17765b4b9
ToppCell10x_5'_v1-Neoplastic-Stem-like-OPC-like-OPC-like|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MAP2 ANLN ULK2

1.11e-031755238a3abf40146ae3459d97cdf865c1c8f6b92ac639
ToppCellRSV-Healthy-2|RSV / Virus stimulation, Condition and Cluster

ANLN SOBP TET1

1.11e-031755230e97189585b7afaf3bd622c3ef10c86412393829
ToppCellTCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Non-keratinizing_Cervical_Squamous_Cell_Carcinoma-3|TCGA-Cervix / Sample_Type by Project: Shred V9

TRERF1 MTSS1 MARK2

1.11e-031755230cc215109d9915af47e4d0a120ce2e46910715fa
ToppCell10x_5'_v1-Neoplastic-Stem-like-OPC-like-OPC-like-Z|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MAP2 ANLN ULK2

1.11e-03175523378d2b79edac91fc74eee0fb42bb29dd9b07c36f
ToppCell367C-Myeloid-Dendritic-cDC_proliferating_2|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

ANLN ZNF621 GAREM1

1.11e-03175523bde785ff0c854646d7ab8571359e9d69a7bf013f
ToppCelldroplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating-classical_monocyte_proliferating_l2|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PTPRN POLA1 PAXIP1

1.13e-031765231510cdfcfb46ce1196a1220c07fb5f3986c81b78
ToppCell390C-Lymphocytic-NK_cells-Proliferating_NK_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

TRIM66 PAXIP1 STIL

1.13e-031765238813c01ea080f373fe3970c5e1ba4c2dca0f7f02
ToppCell390C-Fibroblasts-Fibroblast-B_(Myofibroblast)|390C / Donor, Lineage, Cell class and subclass (all cells)

MXRA5 SLITRK6 SLC4A5

1.13e-03176523852d3da0907fe87c0ef23d75a63ce07619cf0c54
ToppCell3'_v3-Lung-Lymphocytic_T_CD4/8-lo-Cycling_T|Lung / Manually curated celltypes from each tissue

ANLN POLA1 STIL

1.13e-03176523a40dfd8c4ba16757ff929b2f03a0628acf334de4
ToppCell390C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|390C / Donor, Lineage, Cell class and subclass (all cells)

MXRA5 SLITRK6 SLC4A5

1.13e-03176523d2df1e435996c51213e88270af9f928e9e09a6f5
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_3|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

MXRA5 TET1 GAREM1

1.15e-031775233d955ea938a1d2fb1b6d68d4997fd454bd632dfc
ToppCellmetastatic_Brain-Fibroblasts-Undetermined|metastatic_Brain / Location, Cell class and cell subclass

GARNL3 ZFHX4 PRG4

1.15e-0317752354f39be5d90363cfd44dea1a96ae06d3143aa795
ComputationalNeighborhood of ARL3

MAP2 PIK3C2A MAPT PAXIP1 RREB1 ULK2

2.83e-04304336MORF_ARL3
ComputationalNeighborhood of ERCC4

MAP2 PIK3C2A MAPT PAXIP1 RREB1 ULK2

3.79e-04321336MORF_ERCC4
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

MAP2 MTSS1 PEAK1

4.68e-0450333GAVISH_3CA_MALIGNANT_METAPROGRAM_29_NPC_OPC
DiseaseSenile Paranoid Dementia

SLC9A8 MAPT

8.15e-058512C0338630
DiseaseFamilial Dementia

SLC9A8 MAPT

8.15e-058512C0751071
Diseaseanemia (implicated_via_orthology)

SLC4A10 SLC4A5

3.03e-0415512DOID:2355 (implicated_via_orthology)
DiseaseDementia

SLC9A8 MAPT

3.92e-0417512C0497327
Diseasenon-melanoma skin carcinoma

TAF3 ZAN ZFHX4 FARP1

1.14e-03265514EFO_0009260
Diseasecardiac arrhythmia

MAPT NACA

1.24e-0330512EFO_0004269
Diseasehyperuricemia

LRP2 RREB1

1.49e-0333512EFO_0009104
DiseaseSpinocerebellar Ataxia Type 2

SNX14 ATXN7

1.59e-0334512C0752121
DiseaseSpinocerebellar Ataxia Type 1

SNX14 ATXN7

1.59e-0334512C0752120
DiseaseSpinocerebellar Ataxia Type 5

SNX14 ATXN7

1.59e-0334512C0752123
DiseaseSpinocerebellar Ataxia Type 7

SNX14 ATXN7

1.59e-0334512C0752125
DiseaseSpinocerebellar Ataxia Type 6 (disorder)

SNX14 ATXN7

1.59e-0334512C0752124
DiseaseAtaxia, Spinocerebellar

SNX14 ATXN7

1.59e-0334512C0087012
DiseaseSpinocerebellar Ataxia Type 4

SNX14 ATXN7

1.68e-0335512C0752122

Protein segments in the cluster

PeptideGeneStartEntry
TTPPKTSPVPKVTII

IQCN

361

Q9H0B3
PPTKKLTPELTPFVL

PAXIP1

856

Q6ZW49
ARPPVTPVLLEKKSP

PTPRN

436

Q16849
LLPKTPISPLKTGVS

ANLN

316

Q9NQW6
AGPIPIKTPVIPVKT

MTSS1

606

O43312
IKTPVIPVKTPTVPD

MTSS1

611

O43312
TKKTPVLPVTPILSP

PIK3C2A

111

O00443
PSIKPVTPSPSKLVT

PEAK1

846

Q9H792
PPPLPKKILTRTQSL

PEAK3

56

Q6ZS72
KPLSTSPSIPPRTVK

GAREM1

541

Q9H706
PALPKLPSLSSLVKP

LRP2

4456

P98164
ITKPPRPKPATLALT

DEFB127

66

Q9H1M4
KPSPLPVIPDTIKEV

HUWE1

1931

Q7Z6Z7
KKIPPVPSTTSPIST

ATXN7

561

O15265
KIASPVSRKEPPLTP

POLA1

206

P09884
TTVEPPKPIPLTWKT

ERVK-18

16

Q9QC07
PPPTPSGKLVSIKIQ

FARP1

31

Q9Y4F1
SPLPGLERKKTTPTP

MARK2

456

Q7KZI7
KPLLPLFSPIKPVQT

SALL2

236

Q9Y467
PLKSPLVSKVITPPT

GARNL3

866

Q5VVW2
PKSPKVTTHIPQTPV

TAF3

321

Q5VWG9
TSILKLPTKAPGLIP

SLITRK6

301

Q9H5Y7
PTPAPRPLLLKKSVS

SH3D19

136

Q5HYK7
KTPPTPPSSIVAKVQ

PHF12

876

Q96QT6
TKLVLPTPGKPILPV

SLC9A8

31

Q9Y2E8
KPLISTPPVSSQPKV

WAC

466

Q9BTA9
KITTAKPINPRPSLP

PRG4

251

Q92954
KTEPKPPVPVRSLLT

TET1

61

Q8NFU7
PIPSPHPVSQKISKI

STIL

406

Q15468
EPKTLDTLPKPATTP

ZFHX4

2796

Q86UP3
KPKPSRPELTILSPT

SNX14

736

Q9Y5W7
IKTITKAAPAAPPVP

TRO

76

Q12816
PLKPKPLVTPRTVVA

RREB1

506

Q92766
SVTKIPTPVPKSIPI

SOBP

341

A7XYQ1
IITPSPSSHKPVPIK

SP2

166

Q02086
PVPIKPAPIQKSSTT

SP2

176

Q02086
IPSPKLQVPSVFKPT

SLC4A10

781

Q6U841
TPTPPPSLKELLIKE

SNX21

356

Q969T3
PPSKVIKTVTIPTQP

WAPL

601

Q7Z5K2
TPKLHVPSVIKPTRP

SLC4A5

801

Q9BY07
SLPTPPTREPKKVAV

MAPT

531

P10636
IIRTPPKSPATPKQL

MAP2

1646

P11137
KTPLPTIIGSPTKTT

ULK2

591

Q8IYT8
KPVPVTKPVTVSRPI

ZNF512B

286

Q96KM6
LTPTVKPSPVILTPS

ZNF621

421

Q6ZSS3
PAKILPTPPATLKST

PPIP5K2

1186

O43314
LSVKKPPLAPVVSTS

TRIM66

806

O15016
TPLKTTATPLSPLKP

ZMAT4

111

Q9H898
TEPVTLLHSKPPKPT

SNAPC2

131

Q13487
PLKEPVPAITKLVPS

TSHZ1

336

Q6ZSZ6
PLTIPAPVKASSPIK

YEATS2

356

Q9ULM3
PTIPTEKPTISTEKP

ZAN

591

Q9Y493
PTILTEKPTIPSEKP

ZAN

626

Q9Y493
VIPTEKPSIPTEKPS

ZAN

676

Q9Y493
TISPEKPTIPTEKPT

ZAN

711

Q9Y493
PTEKPTIPTEKPTIS

ZAN

741

Q9Y493
TIPTEKPTISPEKPT

ZAN

746

Q9Y493
PTISPEKLTIPTEKP

ZAN

766

Q9Y493
TIPTEKPTIPTEKPT

ZAN

781

Q9Y493
IPTEKPTISPEKPTI

ZAN

901

Q9Y493
STEKPTIPTEKPTIP

ZAN

916

Q9Y493
LTIPTEKPTIPTEKP

ZAN

976

Q9Y493
VSVPVKLLPPKPSSQ

TRERF1

586

Q96PN7
PKGTEVPPLIKTTSP

MXRA5

796

Q9NR99
VPPLIKTTSPPSLSL

MXRA5

801

Q9NR99
TPLSPKGVTLPPKET

NACA

871

E9PAV3
KGVTLPPKETPTPSV

NACA

876

E9PAV3
AVIPLSPKKAPATPV

NACA

1406

E9PAV3