Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

RGPD4 DNAJA3 ARHGAP32 RANGAP1 RGPD8 RGPD3 RALGPS2 RGPD1 RAPGEF1 RIC1 RGPD5

2.36e-075075911GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

RGPD4 DNAJA3 ARHGAP32 RANGAP1 RGPD8 RGPD3 RALGPS2 RGPD1 RAPGEF1 RIC1 RGPD5

2.36e-075075911GO:0030695
GeneOntologyMolecularFunctionSUMO ligase activity

RGPD4 RGPD8 RGPD3 RGPD1

3.21e-0720594GO:0061665
GeneOntologyMolecularFunctionSUMO transferase activity

RGPD4 RGPD8 RGPD3 RGPD1

3.77e-0636594GO:0019789
GeneOntologyMolecularFunctionpeptidyl-prolyl cis-trans isomerase activity

RGPD4 RGPD8 RGPD3 RGPD1

1.43e-0550594GO:0003755
GeneOntologyMolecularFunctionGTPase activator activity

RGPD4 ARHGAP32 RANGAP1 RGPD8 RGPD3 RGPD1 RGPD5

1.77e-05279597GO:0005096
GeneOntologyMolecularFunctioncis-trans isomerase activity

RGPD4 RGPD8 RGPD3 RGPD1

1.81e-0553594GO:0016859
GeneOntologyMolecularFunctionATPase-coupled intramembrane lipid transporter activity

ABCA2 ATP8B4 ATP8A2

7.62e-0528593GO:0140326
GeneOntologyMolecularFunctionenzyme regulator activity

RGPD4 DNAJA3 ARHGAP32 RANGAP1 ABCA2 RGPD8 RGPD3 RALGPS2 RGPD1 RAPGEF1 ADGRV1 RIC1 RGPD5

2.06e-0414185913GO:0030234
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLC25A21 SLC16A1 SLC4A10 SLC35B2 SLC25A25 SLC2A2

2.22e-04293596GO:0008514
GeneOntologyMolecularFunctiongap junction channel activity involved in cell communication by electrical coupling

GJB2 GJB6

3.05e-049592GO:1903763
GeneOntologyMolecularFunctiontransporter activity

GJB2 SLC25A21 ABCA2 ATP8B4 P2RX1 SLC16A1 ATP8A2 GJB6 SLC4A10 SLC35B2 SLC25A25 SLC2A2

3.28e-0412895912GO:0005215
GeneOntologyMolecularFunctionsmall GTPase binding

RGPD4 RANGAP1 RGPD8 RGPD3 RGPD1 RIC1

3.63e-04321596GO:0031267
GeneOntologyMolecularFunctionATP-dependent activity

ACSL6 MYH1 ABCA2 ATP8B4 DDX12P ATP8A2 HSPH1 DNA2

4.25e-04614598GO:0140657
GeneOntologyMolecularFunctionintramembrane lipid transporter activity

ABCA2 ATP8B4 ATP8A2

4.61e-0451593GO:0140303
GeneOntologyMolecularFunction5'-3' DNA helicase activity

DDX12P DNA2

4.64e-0411592GO:0043139
GeneOntologyMolecularFunctionGTPase binding

RGPD4 RANGAP1 RGPD8 RGPD3 RGPD1 RIC1

6.64e-04360596GO:0051020
GeneOntologyMolecularFunctionantiporter activity

SLC25A21 SLC4A10 SLC35B2 SLC25A25

7.40e-04138594GO:0015297
GeneOntologyMolecularFunctionfloppase activity

ABCA2 ATP8A2

1.00e-0316592GO:0140328
GeneOntologyMolecularFunctioncalcium ion binding

GJB2 FAT1 PCDHGB3 MATN1 PAM CLSTN2 ADGRV1 SLC25A25

1.54e-03749598GO:0005509
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC25A21 SLC16A1 SLC4A10 SLC35B2 SLC25A25

1.80e-03296595GO:0015291
GeneOntologyMolecularFunctionpurine ribonucleotide transmembrane transporter activity

SLC35B2 SLC25A25

2.09e-0323592GO:0005346
GeneOntologyMolecularFunctiontransmembrane transporter activity

GJB2 SLC25A21 ABCA2 P2RX1 SLC16A1 GJB6 SLC4A10 SLC35B2 SLC25A25 SLC2A2

2.22e-0311805910GO:0022857
GeneOntologyMolecularFunctiongap junction channel activity

GJB2 GJB6

2.46e-0325592GO:0005243
GeneOntologyMolecularFunctionisomerase activity

RGPD4 RGPD8 RGPD3 RGPD1

2.50e-03192594GO:0016853
GeneOntologyMolecularFunctionadenine nucleotide transmembrane transporter activity

SLC35B2 SLC25A25

2.67e-0326592GO:0000295
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC25A21 ABCA2 SLC16A1 SLC4A10 SLC35B2 SLC25A25

2.78e-03477596GO:0022804
GeneOntologyMolecularFunctionacyl-CoA hydrolase activity

ACOT1 ACOT12

3.09e-0328592GO:0016289
GeneOntologyMolecularFunctionenzyme activator activity

RGPD4 ARHGAP32 RANGAP1 RGPD8 RGPD3 RGPD1 RGPD5

3.10e-03656597GO:0008047
GeneOntologyMolecularFunctionpurine nucleotide transmembrane transporter activity

SLC35B2 SLC25A25

3.31e-0329592GO:0015216
GeneOntologyMolecularFunctiondicarboxylic acid transmembrane transporter activity

SLC25A21 SLC16A1

3.78e-0331592GO:0005310
GeneOntologyMolecularFunctionsolute:inorganic anion antiporter activity

SLC4A10 SLC25A25

4.02e-0332592GO:0005452
GeneOntologyMolecularFunctionnucleotide transmembrane transporter activity

SLC35B2 SLC25A25

4.27e-0333592GO:0015215
GeneOntologyMolecularFunctionwide pore channel activity

GJB2 GJB6

5.35e-0337592GO:0022829
GeneOntologyMolecularFunctionorganophosphate ester transmembrane transporter activity

SLC35B2 SLC25A25

5.93e-0339592GO:0015605
GeneOntologyMolecularFunction4 iron, 4 sulfur cluster binding

DDX12P DNA2

8.52e-0347592GO:0051539
GeneOntologyMolecularFunctionthiolester hydrolase activity

ACOT1 ACOT12

8.52e-0347592GO:0016790
GeneOntologyBiologicalProcessNLS-bearing protein import into nucleus

RGPD4 RGPD8 RGPD3 RGPD1 RGPD5

2.42e-0920595GO:0006607
GeneOntologyBiologicalProcesspositive regulation of glucokinase activity

RGPD4 RGPD8 RGPD3 RGPD1

7.53e-099594GO:0033133
GeneOntologyBiologicalProcesspositive regulation of hexokinase activity

RGPD4 RGPD8 RGPD3 RGPD1

1.25e-0810594GO:1903301
GeneOntologyBiologicalProcessregulation of glucokinase activity

RGPD4 RGPD8 RGPD3 RGPD1

4.23e-0813594GO:0033131
GeneOntologyBiologicalProcessregulation of hexokinase activity

RGPD4 RGPD8 RGPD3 RGPD1

5.92e-0814594GO:1903299
GeneOntologyBiologicalProcessprotein peptidyl-prolyl isomerization

RGPD4 RGPD8 RGPD3 RGPD1

4.14e-0638594GO:0000413
GeneOntologyBiologicalProcessnucleobase-containing compound transport

RGPD4 RGPD8 SUPT6H RGPD3 RGPD1 SLC35B2 SLC25A25

6.86e-06249597GO:0015931
GeneOntologyBiologicalProcessnuclear export

RGPD4 RANGAP1 RGPD8 SUPT6H RGPD3 RGPD1

1.46e-05185596GO:0051168
GeneOntologyBiologicalProcesspeptidyl-proline modification

RGPD4 RGPD8 RGPD3 RGPD1

1.72e-0554594GO:0018208
GeneOntologyBiologicalProcessregulation of gluconeogenesis

RGPD4 RGPD8 RGPD3 RGPD1

5.08e-0571594GO:0006111
GeneOntologyBiologicalProcessmRNA transport

RGPD4 RGPD8 SUPT6H RGPD3 RGPD1

5.91e-05145595GO:0051028
GeneOntologyBiologicalProcessprotein folding

RGPD4 DNAJA3 RGPD8 HSPH1 RGPD3 RGPD1

7.19e-05246596GO:0006457
GeneOntologyBiologicalProcessnuclear transport

RGPD4 RANGAP1 RGPD8 SUPT6H RGPD3 RGPD1 RGPD5

9.87e-05378597GO:0051169
GeneOntologyBiologicalProcessnucleocytoplasmic transport

RGPD4 RANGAP1 RGPD8 SUPT6H RGPD3 RGPD1 RGPD5

9.87e-05378597GO:0006913
GeneOntologyBiologicalProcessRNA transport

RGPD4 RGPD8 SUPT6H RGPD3 RGPD1

1.43e-04175595GO:0050658
GeneOntologyBiologicalProcessnucleic acid transport

RGPD4 RGPD8 SUPT6H RGPD3 RGPD1

1.43e-04175595GO:0050657
GeneOntologyBiologicalProcessestablishment of RNA localization

RGPD4 RGPD8 SUPT6H RGPD3 RGPD1

1.55e-04178595GO:0051236
GeneOntologyBiologicalProcessgap junction-mediated intercellular transport

GJB2 GJB6

1.67e-047592GO:1990349
GeneOntologyBiologicalProcessprotein import into nucleus

RGPD4 RGPD8 RGPD3 RGPD1 RGPD5

2.37e-04195595GO:0006606
GeneOntologyBiologicalProcessimport into nucleus

RGPD4 RGPD8 RGPD3 RGPD1 RGPD5

2.73e-04201595GO:0051170
GeneOntologyBiologicalProcessgluconeogenesis

RGPD4 RGPD8 RGPD3 RGPD1

2.88e-04111594GO:0006094
GeneOntologyBiologicalProcesshexose biosynthetic process

RGPD4 RGPD8 RGPD3 RGPD1

3.29e-04115594GO:0019319
GeneOntologyBiologicalProcessRNA localization

RGPD4 RGPD8 SUPT6H RGPD3 RGPD1

3.88e-04217595GO:0006403
GeneOntologyBiologicalProcessmonosaccharide biosynthetic process

RGPD4 RGPD8 RGPD3 RGPD1

4.00e-04121594GO:0046364
GeneOntologyBiologicalProcessintercellular transport

GJB2 GJB6

4.35e-0411592GO:0010496
GeneOntologyBiologicalProcessregulation of carbohydrate biosynthetic process

RGPD4 RGPD8 RGPD3 RGPD1

5.55e-04132594GO:0043255
GeneOntologyBiologicalProcessprotein localization to nucleus

RGPD4 RANGAP1 RGPD8 RGPD3 RGPD1 RGPD5

5.77e-04362596GO:0034504
GeneOntologyBiologicalProcessregulation of glucose metabolic process

RGPD4 RGPD8 RGPD3 RGPD1

5.88e-04134594GO:0010906
GeneOntologyBiologicalProcessorganic anion transport

ACSL6 SLC25A21 SLC16A1 SLC4A10 SLC35B2 SLC25A25 SLC2A2

6.45e-04515597GO:0015711
GeneOntologyBiologicalProcesslipid translocation

ABCA2 ATP8B4 ATP8A2

6.78e-0460593GO:0034204
GeneOntologyBiologicalProcessregulation of membrane lipid distribution

ABCA2 ATP8B4 ATP8A2

8.56e-0465593GO:0097035
GeneOntologyBiologicalProcesssister chromatid cohesion

PDS5B DDX12P HORMAD1

9.35e-0467593GO:0007062
GeneOntologyCellularComponentcytoplasmic periphery of the nuclear pore complex

RGPD4 RANGAP1 RGPD8 RGPD3 RGPD1

8.38e-128595GO:1990723
GeneOntologyCellularComponentnuclear pore cytoplasmic filaments

RGPD4 RANGAP1 RGPD8 RGPD3 RGPD1

3.75e-1110595GO:0044614
GeneOntologyCellularComponentSUMO ligase complex

RGPD4 RANGAP1 RGPD8 RGPD3 RGPD1

2.96e-0921595GO:0106068
GeneOntologyCellularComponentannulate lamellae

RGPD4 RGPD8 RGPD3 RGPD1

5.61e-0814594GO:0005642
GeneOntologyCellularComponentnuclear pore nuclear basket

RGPD4 RGPD8 RGPD3 RGPD1

1.70e-0718594GO:0044615
GeneOntologyCellularComponentnuclear inclusion body

RGPD4 RGPD8 RGPD3 RGPD1

2.68e-0720594GO:0042405
GeneOntologyCellularComponentnuclear pore

RGPD4 RANGAP1 RGPD8 RGPD3 RGPD1 RGPD5

4.01e-07101596GO:0005643
GeneOntologyCellularComponentinclusion body

RGPD4 RANGAP1 RGPD8 RGPD3 RGPD1

5.51e-0690595GO:0016234
GeneOntologyCellularComponentperinuclear region of cytoplasm

RGPD4 RANGAP1 GJB2 FAT1 RGPD8 RGPD3 RGPD1 RAPGEF1 PAM ADGRV1

2.59e-049345910GO:0048471
GeneOntologyCellularComponentnuclear membrane

RGPD4 RANGAP1 RGPD8 RGPD3 RGPD1 SCRN1

4.44e-04349596GO:0031965
GeneOntologyCellularComponentphospholipid-translocating ATPase complex

ATP8B4 ATP8A2

6.97e-0414592GO:1990531
GeneOntologyCellularComponentnuclear envelope

RGPD4 RANGAP1 RGPD8 RGPD3 RGPD1 SCRN1 RGPD5

9.74e-04560597GO:0005635
GeneOntologyCellularComponentconnexin complex

GJB2 GJB6

1.74e-0322592GO:0005922
HumanPhenoLip fissure

GJB2 GJB6

3.95e-053192HP:0031250
HumanPhenoCobblestone-like hyperkeratosis

GJB2 GJB6

7.87e-054192HP:0031288
HumanPhenoDilatated internal auditory canal

GJB2 GJB6

1.31e-045192HP:0004458
HumanPhenoHair follicle neoplasm

GJB2 GJB6

1.31e-045192HP:0012843
HumanPhenoTrichilemmoma

GJB2 GJB6

1.31e-045192HP:0012844
MousePhenoaneuploidy

RGPD4 PDS5B DDX12P RGPD8 RGPD3 RGPD1 DNA2 HORMAD1

4.49e-1161518MP:0004024
MousePhenoabnormal chromosome number

RGPD4 PDS5B DDX12P RGPD8 RGPD3 RGPD1 DNA2 HORMAD1

7.56e-1086518MP:0004023
MousePhenoabnormal chromosome morphology

RGPD4 PDS5B DDX12P RGPD8 RGPD3 RGPD1 DNA2 HORMAD1

1.60e-08126518MP:0003702
MousePhenoelevated level of mitotic sister chromatid exchange

RGPD4 RGPD8 RGPD3 RGPD1

2.77e-0716514MP:0003701
MousePhenoabnormal cell nucleus morphology

RGPD4 PDS5B DDX12P RGPD8 RGPD3 RGPD1 DNA2 HORMAD1

3.04e-07184518MP:0003111
MousePhenoabnormal morula morphology

RGPD4 RGPD8 RGPD3 RGPD1

2.21e-0626514MP:0012058
MousePhenoincreased liver tumor incidence

RGPD4 RGPD8 RGPD3 RGPD1 DNA2 ACOT12

2.95e-06111516MP:0008019
MousePhenoincreased hepatobiliary system tumor incidence

RGPD4 RGPD8 RGPD3 RGPD1 DNA2 ACOT12

2.95e-06111516MP:0010297
MousePhenodecreased tumor latency

RGPD4 RGPD8 RGPD3 RGPD1

4.02e-0630514MP:0010308
MousePhenofailure of blastocyst formation

RGPD4 RGPD8 RGPD3 RGPD1

4.60e-0631514MP:0012129
MousePhenoincreased hepatocellular carcinoma incidence

RGPD4 RGPD8 RGPD3 RGPD1 ACOT12

5.35e-0670515MP:0003331
MousePhenoabnormal tumor latency

RGPD4 RGPD8 RGPD3 RGPD1

6.72e-0634514MP:0010307
MousePhenoabnormal mitosis

RGPD4 PDS5B RGPD8 RGPD3 RGPD1 DNA2

6.73e-06128516MP:0004046
MousePhenoincreased lung carcinoma incidence

RGPD4 RGPD8 RGPD3 RGPD1 DNA2

9.13e-0678515MP:0008714
MousePhenoabnormal blastocyst formation

RGPD4 RGPD8 RGPD3 RGPD1

1.18e-0539514MP:0012128
MousePhenoabnormal eye electrophysiology

RGPD4 RGPD8 ATP8A2 RGPD3 NR2E1 RGPD1 ADGRV1

1.76e-05228517MP:0005551
MousePhenodecreased susceptibility to diet-induced obesity

RGPD4 RGPD8 SLC16A1 RGPD3 RGPD1 SLC25A25

2.41e-05160516MP:0005659
MousePhenoabnormal preimplantation embryo development

RGPD4 DCAF13 RGPD8 RGPD3 RGPD1 HORMAD1

3.50e-05171516MP:0009781
MousePhenoincreased lung tumor incidence

RGPD4 RGPD8 RGPD3 RGPD1 DNA2

4.25e-05107515MP:0008014
MousePhenoincreased respiratory system tumor incidence

RGPD4 RGPD8 RGPD3 RGPD1 DNA2

4.25e-05107515MP:0010298
MousePhenodecreased susceptibility to weight gain

RGPD4 RGPD8 SLC16A1 RGPD3 RGPD1 SLC25A25

5.61e-05186516MP:0010182
MousePhenoabnormal rod electrophysiology

RGPD4 RGPD8 ATP8A2 RGPD3 RGPD1

7.06e-05119515MP:0004021
MousePhenoincreased energy expenditure

RGPD4 RGPD8 SLC16A1 RGPD3 RGPD1 SLC25A25

7.50e-05196516MP:0004889
MousePhenoincreased carcinoma incidence

RGPD4 RGPD8 RGPD3 RGPD1 DNA2 ACOT12

7.71e-05197516MP:0002038
MousePhenoincreased lipogenesis

ACSL6 GPR61

7.79e-054512MP:0020867
MousePhenoembryonic lethality before implantation, complete penetrance

RGPD4 DCAF13 RGPD8 SUPT6H RGPD3 RGPD1

9.10e-05203516MP:0011094
MousePhenoabnormal cell cycle

RGPD4 PDS5B DDX12P RGPD8 RGPD3 RGPD1 DNA2 HORMAD1 LFNG

9.60e-05520519MP:0003077
MousePhenoincreased incidence of tumors by chemical induction

RGPD4 RGPD8 RGPD3 RGPD1 ACOT12

1.57e-04141515MP:0004499
MousePhenoincreased malignant tumor incidence

RGPD4 RGPD8 RGPD3 RGPD1 DNA2 ACOT12

2.12e-04237516MP:0002018
MousePhenoembryonic lethality before implantation

RGPD4 DCAF13 RGPD8 SUPT6H RGPD3 RGPD1

2.37e-04242516MP:0006204
MousePhenoincreased incidence of induced tumors

RGPD4 RGPD8 RGPD3 RGPD1 ACOT12

4.06e-04173515MP:0002021
MousePhenoenlarged epididymis

RGPD4 RGPD8 RGPD3 RGPD1

4.58e-0499514MP:0004931
MousePhenoincreased sarcoma incidence

RGPD4 RGPD8 RGPD3 RGPD1

5.13e-04102514MP:0002032
MousePhenoabnormal preimplantation embryo morphology

RGPD4 RANGAP1 DCAF13 RGPD8 RGPD3 RGPD1

5.47e-04283516MP:0014137
MousePhenoabnormal lipogenesis

ACSL6 GPR61

5.76e-0410512MP:0020866
MousePhenofailure of blastocyst to hatch from the zona pellucida

RGPD4 RGPD8 RGPD3 RGPD1

6.15e-04107514MP:0003694
MousePhenoabnormal intracellular organelle morphology

RGPD4 PDS5B DDX12P RGPD8 RGPD3 RGPD1 DNA2 HORMAD1

7.44e-04546518MP:0014239
MousePhenoabnormal blastocyst hatching

RGPD4 RGPD8 RGPD3 RGPD1

7.55e-04113514MP:0003693
MousePhenooptic nerve degeneration

ATP8A2 NR2E1

8.41e-0412512MP:0006219
MousePhenoabnormal susceptibility to weight gain

RGPD4 RGPD8 SLC16A1 RGPD3 RGPD1 SLC25A25

8.67e-04309516MP:0011117
MousePhenoabnormal energy expenditure

RGPD4 RGPD8 SLC16A1 RGPD3 RGPD1 SLC25A25

9.27e-04313516MP:0005450
MousePhenoabnormal embryo development

RGPD4 AMD1 RANGAP1 GJB2 DCAF13 DDX12P RGPD8 RGPD3 RGPD1 BCOR CARS2 HORMAD1 LFNG

9.93e-0413705113MP:0001672
MousePhenoabnormal energy homeostasis

RGPD4 RGPD8 SLC16A1 RGPD3 RGPD1 SLC25A25

1.07e-03322516MP:0005448
MousePhenoabnormal startle reflex

ACSL6 MYH1 ABCA2 GPR61 ATP8A2 SLC4A10 ADGRV1 ITK

1.24e-03591518MP:0001486
MousePhenoembryonic lethality prior to organogenesis, complete penetrance

RGPD4 DNAJA3 AMD1 DCAF13 RGPD8 SUPT6H RGPD3 RGPD1 RAPGEF1

1.71e-03772519MP:0014259
DomainGrip

RGPD4 RGPD8 RGPD3 RGPD1 RGPD5

1.10e-1011585SM00755
DomainGRIP

RGPD4 RGPD8 RGPD3 RGPD1 RGPD5

1.10e-1011585PF01465
DomainRan_BP1

RGPD4 RGPD8 RGPD3 RGPD1 RGPD5

1.89e-1012585PF00638
DomainGRIP_dom

RGPD4 RGPD8 RGPD3 RGPD1 RGPD5

1.89e-1012585IPR000237
DomainGRIP

RGPD4 RGPD8 RGPD3 RGPD1 RGPD5

1.89e-1012585PS50913
DomainRANBD1

RGPD4 RGPD8 RGPD3 RGPD1 RGPD5

1.89e-1012585PS50196
DomainRanBD

RGPD4 RGPD8 RGPD3 RGPD1 RGPD5

3.06e-1013585SM00160
DomainRan_bind_dom

RGPD4 RGPD8 RGPD3 RGPD1 RGPD5

3.06e-1013585IPR000156
DomainGCC2_Rab_bind

RGPD4 RGPD8 RGPD3 RGPD1

2.91e-097584IPR032023
DomainRab_bind

RGPD4 RGPD8 RGPD3 RGPD1

2.91e-097584PF16704
Domain-

RGPD4 RGPD8 RGPD3 RGPD1

1.73e-08105841.10.220.60
DomainTPR-contain_dom

RGPD4 RGPD8 RGPD3 RGPD1 TTC5 RGPD5

6.96e-06150586IPR013026
DomainTPR-like_helical_dom

RGPD4 RGPD8 RGPD3 RGPD1 TRAPPC8 TTC5 RGPD5

7.52e-06233587IPR011990
DomainTPR_REGION

RGPD4 RGPD8 RGPD3 RGPD1 TTC5 RGPD5

1.20e-05165586PS50293
DomainTPR

RGPD4 RGPD8 RGPD3 RGPD1 TTC5 RGPD5

1.20e-05165586PS50005
Domain-

RGPD4 RGPD8 RGPD3 RGPD1 TRAPPC8 TTC5

4.32e-052075861.25.40.10
DomainTPR

RGPD4 RGPD8 RGPD3 RGPD1 TTC5

4.97e-05129585SM00028
DomainTPR_repeat

RGPD4 RGPD8 RGPD3 RGPD1 TTC5

5.75e-05133585IPR019734
DomainTPR_1

RGPD8 RGPD1 TTC5 RGPD5

1.75e-0490584PF00515
DomainTPR_1

RGPD8 RGPD1 TTC5 RGPD5

1.75e-0490584IPR001440
DomainPH_dom-like

RGPD4 RGPD8 RGPD3 RALGPS2 RGPD1 ITK RGPD5

3.37e-04426587IPR011993
DomainP_typ_ATPase_c

ATP8B4 ATP8A2

8.42e-0414582IPR032630
DomainP-type_ATPase_N

ATP8B4 ATP8A2

8.42e-0414582IPR032631
DomainP-type_ATPase_IV

ATP8B4 ATP8A2

8.42e-0414582IPR006539
DomainPhoLip_ATPase_C

ATP8B4 ATP8A2

8.42e-0414582PF16212
DomainPhoLip_ATPase_N

ATP8B4 ATP8A2

8.42e-0414582PF16209
Domain-

RGPD4 RGPD8 RGPD3 RALGPS2 RGPD1 ITK

1.31e-033915862.30.29.30
DomainCONNEXINS_1

GJB2 GJB6

1.57e-0319582PS00407
DomainCONNEXINS_2

GJB2 GJB6

1.74e-0320582PS00408
DomainConnexin

GJB2 GJB6

1.74e-0320582IPR000500
DomainConnexin_CCC

GJB2 GJB6

1.74e-0320582IPR019570
DomainConnexin_N

GJB2 GJB6

1.74e-0320582IPR013092
DomainConnexin

GJB2 GJB6

1.74e-0320582PF00029
DomainConnexin_CCC

GJB2 GJB6

1.74e-0320582SM01089
DomainConnexin_CS

GJB2 GJB6

1.74e-0320582IPR017990
DomainCNX

GJB2 GJB6

1.74e-0320582SM00037
DomainRASGEF

RALGPS2 RAPGEF1

2.94e-0326582PS00720
Domain-

FAT1 CLSTN2 ADGRV1

3.21e-03955832.60.120.200
DomainRASGEF_CAT

RALGPS2 RAPGEF1

3.65e-0329582PS50009
DomainRasGEF

RALGPS2 RAPGEF1

3.90e-0330582PF00617
Domain-

RALGPS2 RAPGEF1

3.90e-03305821.10.840.10
DomainRas_GEF_dom

RALGPS2 RAPGEF1

3.90e-0330582IPR023578
DomainRASGEF_cat_dom

RALGPS2 RAPGEF1

3.90e-0330582IPR001895
DomainRasGEF

RALGPS2 RAPGEF1

3.90e-0330582SM00147
Domain-

ATP8B4 ATP8A2

4.43e-03325823.40.1110.10
DomainMit_carrier

SLC25A21 SLC25A25

4.43e-0332582IPR002067
Domain-

ATP8B4 ATP8A2

4.43e-03325822.70.150.10
DomainConA-like_dom

FAT1 COL15A1 CLSTN2 ADGRV1

4.76e-03219584IPR013320
PathwayBIOCARTA_RANBP2_PATHWAY

RGPD4 RANGAP1 RGPD8 RGPD3 RGPD1

2.74e-0918475MM1549
PathwayREACTOME_SUMOYLATION_OF_DNA_REPLICATION_PROTEINS

RGPD4 RANGAP1 RGPD8 RGPD3 RGPD1

6.93e-0751475MM15151
PathwayREACTOME_RESOLUTION_OF_SISTER_CHROMATID_COHESION

RGPD4 PDS5B RANGAP1 RGPD8 RGPD3 RGPD1

4.13e-06129476MM14894
PathwayREACTOME_REGULATION_OF_HSF1_MEDIATED_HEAT_SHOCK_RESPONSE

RGPD4 RGPD8 HSPH1 RGPD3 RGPD1

4.20e-0673475MM14948
PathwayREACTOME_NUCLEAR_PORE_COMPLEX_NPC_DISASSEMBLY

RGPD4 RGPD8 RGPD3 RGPD1

9.08e-0640474MM14945
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_SMALL_RNAS

RGPD4 RGPD8 RGPD3 RGPD1

1.00e-0541474MM15200
PathwayREACTOME_SUMOYLATION_OF_SUMOYLATION_PROTEINS

RGPD4 RGPD8 RGPD3 RGPD1

1.11e-0542474MM15039
PathwayREACTOME_TRANSPORT_OF_THE_SLBP_DEPENDANT_MATURE_MRNA

RGPD4 RGPD8 RGPD3 RGPD1

1.22e-0543474MM14609
PathwayREACTOME_CELLULAR_RESPONSE_TO_HEAT_STRESS

RGPD4 RGPD8 HSPH1 RGPD3 RGPD1

1.31e-0592475MM14951
PathwayREACTOME_SUMOYLATION_OF_UBIQUITINYLATION_PROTEINS

RGPD4 RGPD8 RGPD3 RGPD1

1.74e-0547474MM14939
PathwayREACTOME_AMPLIFICATION_OF_SIGNAL_FROM_THE_KINETOCHORES

RGPD4 RANGAP1 RGPD8 RGPD3 RGPD1

1.97e-05100475MM14561
PathwayREACTOME_GENE_SILENCING_BY_RNA

RGPD4 RGPD8 RGPD3 RGPD1

2.06e-0549474MM14837
PathwayREACTOME_TRANSPORT_OF_MATURE_MRNAS_DERIVED_FROM_INTRONLESS_TRANSCRIPTS

RGPD4 RGPD8 RGPD3 RGPD1

2.23e-0550474MM14610
PathwayREACTOME_NUCLEAR_ENVELOPE_BREAKDOWN

RGPD4 RGPD8 RGPD3 RGPD1

3.27e-0555474MM14917
PathwayREACTOME_SUMOYLATION_OF_RNA_BINDING_PROTEINS

RGPD4 RGPD8 RGPD3 RGPD1

4.03e-0558474MM15149
PathwayREACTOME_SNRNP_ASSEMBLY

RGPD4 RGPD8 RGPD3 RGPD1

4.03e-0558474MM14736
PathwayREACTOME_SEPARATION_OF_SISTER_CHROMATIDS

RGPD4 PDS5B RANGAP1 RGPD8 RGPD3 RGPD1

4.10e-05193476MM14890
PathwayREACTOME_MITOTIC_SPINDLE_CHECKPOINT

RGPD4 RANGAP1 RGPD8 RGPD3 RGPD1

4.20e-05117475MM15387
PathwayREACTOME_MITOTIC_PROMETAPHASE

RGPD4 PDS5B RANGAP1 RGPD8 RGPD3 RGPD1

5.29e-05202476MM15362
PathwayREACTOME_SUMOYLATION_OF_CHROMATIN_ORGANIZATION_PROTEINS

RGPD4 RGPD8 RGPD3 RGPD1

6.33e-0565474MM15147
PathwayREACTOME_RHO_GTPASES_ACTIVATE_FORMINS

RGPD4 RANGAP1 RGPD8 RGPD3 RGPD1

1.02e-04141475MM15266
PathwayREACTOME_MITOTIC_METAPHASE_AND_ANAPHASE

RGPD4 PDS5B RANGAP1 RGPD8 RGPD3 RGPD1

1.19e-04234476MM14898
PathwayREACTOME_GLUCOSE_METABOLISM

RGPD4 RGPD8 RGPD3 RGPD1

1.57e-0482474MM15394
PathwayREACTOME_SUMOYLATION_OF_DNA_DAMAGE_RESPONSE_AND_REPAIR_PROTEINS

RGPD4 RGPD8 RGPD3 RGPD1

1.72e-0484474MM14929
PathwayREACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM

RGPD4 RGPD8 RGPD3 RGPD1

1.89e-0486474MM15413
PathwayREACTOME_SUMOYLATION

RGPD4 RANGAP1 RGPD8 RGPD3 RGPD1

2.38e-04169475MM14919
PathwayREACTOME_CELL_CYCLE_CHECKPOINTS

RGPD4 RANGAP1 RGPD8 RGPD3 RGPD1 DNA2

2.65e-04271476MM15388
PathwayREACTOME_MITOTIC_PROPHASE

RGPD4 RGPD8 RGPD3 RGPD1

5.53e-04114474MM15361
PathwayREACTOME_RHO_GTPASE_EFFECTORS

RGPD4 RANGAP1 RGPD8 RGPD3 RGPD1

1.59e-03257475MM14755
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

ABCA2 ATP8B4 SLC16A1 ATP8A2 SLC4A10 SLC35B2 ALB SLC2A2

1.68e-03681478MM14985
PathwayREACTOME_M_PHASE

RGPD4 PDS5B RANGAP1 RGPD8 RGPD3 RGPD1

1.71e-03387476MM15364
PathwayREACTOME_METABOLISM_OF_CARBOHYDRATES

RGPD4 RGPD8 RGPD3 RGPD1 SLC35B2

2.01e-03271475MM15406
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

ABCA2 ATP8B4 SLC16A1 ATP8A2 SLC4A10 SLC35B2 ALB SLC2A2

2.73e-03736478M27287
Pubmed

Complex genomic rearrangements lead to novel primate gene function.

RGPD4 RGPD8 RGPD3 RGPD1 RGPD5

2.70e-13760515710750
Pubmed

The RanBP2/RanGAP1*SUMO1/Ubc9 SUMO E3 ligase is a disassembly machine for Crm1-dependent nuclear export complexes.

RGPD4 RANGAP1 RGPD8 RGPD3 RGPD1

3.23e-121060527160050
Pubmed

T-cell receptor (TCR) signaling promotes the assembly of RanBP2/RanGAP1-SUMO1/Ubc9 nuclear pore subcomplex via PKC-θ-mediated phosphorylation of RanGAP1.

RGPD4 RANGAP1 RGPD8 RGPD3 RGPD1

5.91e-121160534110283
Pubmed

Nup358, a nucleoporin, functions as a key determinant of the nuclear pore complex structure remodeling during skeletal myogenesis.

RGPD4 RGPD8 RGPD3 RGPD1

2.79e-10760421205196
Pubmed

Haploinsufficiency of RanBP2 is neuroprotective against light-elicited and age-dependent degeneration of photoreceptor neurons.

RGPD4 RGPD8 RGPD3 RGPD1

2.79e-10760418949001
Pubmed

Selective impairment of a subset of Ran-GTP-binding domains of ran-binding protein 2 (Ranbp2) suffices to recapitulate the degeneration of the retinal pigment epithelium (RPE) triggered by Ranbp2 ablation.

RGPD4 RGPD8 RGPD3 RGPD1

2.79e-10760425187515
Pubmed

Interconversion of red opsin isoforms by the cyclophilin-related chaperone protein Ran-binding protein 2.

RGPD4 RGPD8 RGPD3 RGPD1

2.79e-1076049037092
Pubmed

Localization of the Ran-GTP binding protein RanBP2 at the cytoplasmic side of the nuclear pore complex.

RGPD4 RGPD8 RGPD3 RGPD1

2.79e-1076048603673
Pubmed

Uncoupling phototoxicity-elicited neural dysmorphology and death by insidious function and selective impairment of Ran-binding protein 2 (Ranbp2).

RGPD4 RGPD8 RGPD3 RGPD1

2.79e-10760426632511
Pubmed

Differential loss of prolyl isomerase or chaperone activity of Ran-binding protein 2 (Ranbp2) unveils distinct physiological roles of its cyclophilin domain in proteostasis.

RGPD4 RGPD8 RGPD3 RGPD1

2.79e-10760424403063
Pubmed

Distinct and atypical intrinsic and extrinsic cell death pathways between photoreceptor cell types upon specific ablation of Ranbp2 in cone photoreceptors.

RGPD4 RGPD8 RGPD3 RGPD1

2.79e-10760423818861
Pubmed

Genomic organization, expression, and localization of murine Ran-binding protein 2 (RanBP2) gene.

RGPD4 RGPD8 RGPD3 RGPD1

2.79e-10760411353387
Pubmed

Microglial activation in an amyotrophic lateral sclerosis-like model caused by Ranbp2 loss and nucleocytoplasmic transport impairment in retinal ganglion neurons.

RGPD4 RGPD8 RGPD3 RGPD1

2.79e-10760430944974
Pubmed

Nucleoporin Nup358 drives the differentiation of myeloid-biased multipotent progenitors by modulating HDAC3 nuclear translocation.

RGPD4 RGPD8 RGPD3 RGPD1

2.79e-10760438838144
Pubmed

Kinesin-1 and mitochondrial motility control by discrimination of structurally equivalent but distinct subdomains in Ran-GTP-binding domains of Ran-binding protein 2.

RGPD4 RGPD8 RGPD3 RGPD1

2.79e-10760423536549
Pubmed

Retina-specifically expressed novel subtypes of bovine cyclophilin.

RGPD4 RGPD8 RGPD3 RGPD1

2.79e-1076047559465
Pubmed

Mst1, RanBP2 and eIF4G are new markers for in vivo PI3K activation in murine and human prostate.

RGPD4 RGPD8 RGPD3 RGPD1

2.79e-10760417372272
Pubmed

Proteostatic Remodeling of Small Heat Shock Chaperones─Crystallins by Ran-Binding Protein 2─and the Peptidyl-Prolyl cis-trans Isomerase and Chaperone Activities of Its Cyclophilin Domain.

RGPD4 RGPD8 RGPD3 RGPD1

2.79e-10760438657106
Pubmed

Identification of RanBP2- and kinesin-mediated transport pathways with restricted neuronal and subcellular localization.

RGPD4 RGPD8 RGPD3 RGPD1

2.79e-10760412191015
Pubmed

Ranbp2 haploinsufficiency mediates distinct cellular and biochemical phenotypes in brain and retinal dopaminergic and glia cells elicited by the Parkinsonian neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).

RGPD4 RGPD8 RGPD3 RGPD1

2.79e-10760422821000
Pubmed

Neuroprotection resulting from insufficiency of RANBP2 is associated with the modulation of protein and lipid homeostasis of functionally diverse but linked pathways in response to oxidative stress.

RGPD4 RGPD8 RGPD3 RGPD1

2.79e-10760420682751
Pubmed

Terminal differentiation of cortical neurons rapidly remodels RanGAP-mediated nuclear transport system.

RGPD4 RANGAP1 RGPD8 RGPD3 RGPD1

3.32e-102260527717094
Pubmed

The distribution of phosphorylated SR proteins and alternative splicing are regulated by RANBP2.

RGPD4 RGPD8 RGPD3 RGPD1

5.57e-10860422262462
Pubmed

The nucleoporin RanBP2 tethers the cAMP effector Epac1 and inhibits its catalytic activity.

RGPD4 RGPD8 RGPD3 RGPD1

5.57e-10860421670213
Pubmed

Zap70 and downstream RanBP2 are required for the exact timing of the meiotic cell cycle in oocytes.

RGPD4 RGPD8 RGPD3 RGPD1

5.57e-10860428745977
Pubmed

Critical role of RanBP2-mediated SUMOylation of Small Heterodimer Partner in maintaining bile acid homeostasis.

RGPD4 RGPD8 RGPD3 RGPD1

5.57e-10860427412403
Pubmed

Mice lacking Ran binding protein 1 are viable and show male infertility.

RGPD4 RGPD8 RGPD3 RGPD1

5.57e-10860421310149
Pubmed

Resolution of sister centromeres requires RanBP2-mediated SUMOylation of topoisomerase IIalpha.

RGPD4 RGPD8 RGPD3 RGPD1

1.00e-09960418394993
Pubmed

The docking of kinesins, KIF5B and KIF5C, to Ran-binding protein 2 (RanBP2) is mediated via a novel RanBP2 domain.

RGPD4 RGPD8 RGPD3 RGPD1

1.00e-09960411553612
Pubmed

The zinc finger cluster domain of RanBP2 is a specific docking site for the nuclear export factor, exportin-1.

RGPD4 RGPD8 RGPD3 RGPD1

1.00e-09960410601307
Pubmed

The cyclophilin-like domain mediates the association of Ran-binding protein 2 with subunits of the 19 S regulatory complex of the proteasome.

RGPD4 RGPD8 RGPD3 RGPD1

1.00e-0996049733766
Pubmed

Loss of Ranbp2 in motoneurons causes disruption of nucleocytoplasmic and chemokine signaling, proteostasis of hnRNPH3 and Mmp28, and development of amyotrophic lateral sclerosis-like syndromes.

RGPD4 RGPD8 RGPD3 RGPD1

1.00e-09960428100513
Pubmed

Impairments in age-dependent ubiquitin proteostasis and structural integrity of selective neurons by uncoupling Ran GTPase from the Ran-binding domain 3 of Ranbp2 and identification of novel mitochondrial isoforms of ubiquitin-conjugating enzyme E2I (ubc9) and Ranbp2.

RGPD4 RGPD8 RGPD3 RGPD1

1.00e-09960428877029
Pubmed

Association of the kinesin-binding domain of RanBP2 to KIF5B and KIF5C determines mitochondria localization and function.

RGPD4 RGPD8 RGPD3 RGPD1

1.00e-09960417887960
Pubmed

Cyclophilin-related protein RanBP2 acts as chaperone for red/green opsin.

RGPD4 RGPD8 RGPD3 RGPD1

1.67e-09106048857542
Pubmed

Parkin ubiquitinates and promotes the degradation of RanBP2.

RGPD4 RGPD8 RGPD3 RGPD1

1.67e-091060416332688
Pubmed

Ran-dependent docking of importin-beta to RanBP2/Nup358 filaments is essential for protein import and cell viability.

RGPD4 RGPD8 RGPD3 RGPD1

1.67e-091060421859863
Pubmed

An Rtn4/Nogo-A-interacting micropeptide modulates synaptic plasticity with age.

RGPD4 RGPD8 RGPD3 RGPD1

2.62e-091160435771867
Pubmed

RanBP2 modulates Cox11 and hexokinase I activities and haploinsufficiency of RanBP2 causes deficits in glucose metabolism.

RGPD4 RGPD8 RGPD3 RGPD1

2.62e-091160417069463
Pubmed

Ankyrin-G induces nucleoporin Nup358 to associate with the axon initial segment of neurons.

RGPD4 RGPD8 RGPD3 RGPD1

5.65e-091360431427429
Pubmed

A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.

RGPD4 RANGAP1 RGPD8 SUPT6H RGPD3 RGPD1 BCOR

6.37e-0914660723892456
Pubmed

Limited expression of nuclear pore membrane glycoprotein 210 in cell lines and tissues suggests cell-type specific nuclear pores in metazoans.

RGPD4 RGPD8 RGPD3 RGPD1

1.08e-081560414697343
Pubmed

Early Hearing Loss upon Disruption of Slc4a10 in C57BL/6 Mice.

GJB2 GJB6 SLC4A10

9.73e-08660331001720
Pubmed

Peering through the pore: nuclear pore complex structure, assembly, and function.

RGPD4 RGPD8 RGPD3 RGPD1

5.65e-073860412791264
Pubmed

Strain background effects and genetic modifiers of hearing in mice.

GJB2 GJB6 ADGRV1

7.97e-071160316579977
Pubmed

C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.

RGPD4 DNAJA3 RANGAP1 SLC25A21 DDX12P RGPD8 SLC16A1 HSPH1 RGPD3 RGPD1 DNA2 RGPD5

1.33e-061257601237317656
Pubmed

Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1.

RGPD4 RGPD8 RGPD3 RGPD1 BCOR RGPD5

1.97e-0621560635973513
Pubmed

Frequency of GJB2 mutations, GJB6-D13S1830 and GJB6-D13S1854 deletions among patients with non-syndromic hearing loss from the central region of Iran.

GJB2 GJB6

2.93e-06260231162818
Pubmed

First report of prevalence c.IVS1+1G>A and del (GJB6-13S1854) mutations in Syrian families with non-syndromic sensorineural hearing loss.

GJB2 GJB6

2.93e-06260228012540
Pubmed

The digenic hypothesis unraveled: the GJB6 del(GJB6-D13S1830) mutation causes allele-specific loss of GJB2 expression in cis.

GJB2 GJB6

2.93e-06260219723508
Pubmed

A study of GJB2 and delGJB6-D13S1830 mutations in Brazilian non-syndromic deaf children from the Amazon region.

GJB2 GJB6

2.93e-06260223503914
Pubmed

Prevalence of DFNB1 mutations among cochlear implant users in Slovakia and its clinical implications.

GJB2 GJB6

2.93e-06260223700267
Pubmed

[New recurrent extended deletion, including GJB2 and GJB6 genes, results in isolated sensorineural hearing impairment with autosomal recessive type of inheritance].

GJB2 GJB6

2.93e-06260225715449
Pubmed

A novel DFNB1 deletion allele supports the existence of a distant cis-regulatory region that controls GJB2 and GJB6 expression.

GJB2 GJB6

2.93e-06260220236118
Pubmed

Connexin 26 variants and auditory neuropathy/dys-synchrony among children in schools for the deaf.

GJB2 GJB6

2.93e-06260216222667
Pubmed

Connexin26 gap junction mediates miRNA intercellular genetic communication in the cochlea and is required for inner ear development.

GJB2 GJB6

2.93e-06260226490746
Pubmed

Prevalence of DFNB1 mutations in Argentinean children with non-syndromic deafness. Report of a novel mutation in GJB2.

GJB2 GJB6

2.93e-06260220022641
Pubmed

GJB2 and GJB6 genes: molecular study and identification of novel GJB2 mutations in the hearing-impaired Argentinean population.

GJB2 GJB6

2.93e-06260219887791
Pubmed

Hearing impairment in Dutch patients with connexin 26 (GJB2) and connexin 30 (GJB6) mutations.

GJB2 GJB6

2.93e-06260215656949
Pubmed

The association between GJB2 mutation and GJB6 gene in non syndromic hearing loss school children.

GJB2 GJB6

2.93e-06260222106692
Pubmed

GJB2 and GJB6 Genetic Variant Curation in an Argentinean Non-Syndromic Hearing-Impaired Cohort.

GJB2 GJB6

2.93e-06260233096615
Pubmed

Mutation R184Q of connexin 26 in hearing loss patients has a dominant-negative effect on connexin 26 and connexin 30.

GJB2 GJB6

2.93e-06260220442751
Pubmed

Melanoma progression exhibits a significant impact on connexin expression patterns in the epidermal tumor microenvironment.

GJB2 GJB6

2.93e-06260219844737
Pubmed

Common mutation analysis of GJB2 and GJB6 genes in affected families with autosomal recessive non-syndromic hearing loss from Iran: simultaneous detection of two common mutations (35delG/del(GJB6-D13S1830)) in the DFNB1-related deafness.

GJB2 GJB6

2.93e-06260217368814
Pubmed

Connexin Type and Fluorescent Protein Fusion Tag Determine Structural Stability of Gap Junction Plaques.

GJB2 GJB6

2.93e-06260226265468
Pubmed

GJB2 and GJB6 mutations are an infrequent cause of autosomal-recessive nonsyndromic hearing loss in residents of Mexico.

GJB2 GJB6

2.93e-06260225288386
Pubmed

GJB2 (connexin 26) variants and nonsyndromic sensorineural hearing loss: a HuGE review.

GJB2 GJB6

2.93e-06260212172392
Pubmed

Prevalence of DFNB1 mutations in Slovak patients with non-syndromic hearing loss.

GJB2 GJB6

2.93e-06260222281373
Pubmed

Particular distribution of the GJB2/GJB6 gene mutations in Mexican population with hearing impairment.

GJB2 GJB6

2.93e-06260224774219
Pubmed

GJB2 mutation spectrum in 209 hearing impaired individuals of predominantly Caribbean Hispanic and African descent.

GJB2 GJB6

2.93e-06260220381175
Pubmed

Infant hearing loss and connexin testing in a diverse population.

GJB2 GJB6

2.93e-06260218580690
Pubmed

The spectrum of GJB2 gene mutations in Algerian families with nonsyndromic hearing loss from Sahara and Kabylie regions.

GJB2 GJB6

2.93e-06260231200317
Pubmed

Phenotypic variability of non-syndromic hearing loss in patients heterozygous for both c.35delG of GJB2 and the 342-kb deletion involving GJB6.

GJB2 GJB6

2.93e-06260214759569
Pubmed

Mutation analysis of GJB2 and GJB6 genes in Southeastern Brazilians with hereditary nonsyndromic deafness.

GJB2 GJB6

2.93e-06260220563649
Pubmed

Double heterozygosity with mutations involving both the GJB2 and GJB6 genes is a possible, but very rare, cause of congenital deafness in the Czech population.

GJB2 GJB6

2.93e-06260215638823
Pubmed

Decreased expression of connexin-30 and aberrant expression of connexin-26 in human head and neck cancer.

GJB2 GJB6

2.93e-06260217695503
Pubmed

Phenotype/genotype correlations in a DFNB1 cohort with ethnical diversity.

GJB2 GJB6

2.93e-06260218758381
Pubmed

Performance of speech perception after cochlear implantation in DFNB1 patients.

GJB2 GJB6

2.93e-06260219051073
Pubmed

GJB2 and GJB6 gene mutations found in Indian probands with congenital hearing impairment.

GJB2 GJB6

2.93e-06260220086291
Pubmed

Non-syndromic hearing impairment in a multi-ethnic population of Northeastern Brazil.

GJB2 GJB6

2.93e-06260223684175
Pubmed

A deletion mutation in GJB6 cooperating with a GJB2 mutation in trans in non-syndromic deafness: A novel founder mutation in Ashkenazi Jews.

GJB2 GJB6

2.93e-06260211668644
Pubmed

Pediatric cholesteatoma and variants in the gene encoding connexin 26.

GJB2 GJB6

2.93e-06260219877196
Pubmed

Detection of the 35delG/GJB2 and del(GJB6-D13S1830) mutations in Venezuelan patients with autosomal recessive nonsyndromic hearing loss.

GJB2 GJB6

2.93e-06260218294049
Pubmed

Hearing loss features in GJB2 biallelic mutations and GJB2/GJB6 digenic inheritance in a large Italian cohort.

GJB2 GJB6

2.93e-06260219173109
Pubmed

Prevalence of GJB2 mutations and the del(GJB6-D13S1830) in Argentinean non-syndromic deaf patients.

GJB2 GJB6

2.93e-06260215964725
Pubmed

Screening for the GJB2 c.-3170 G>A (IVS 1+1 G>A) mutation in Brazilian deaf individuals using multiplex ligation-dependent probe amplification.

GJB2 GJB6

2.93e-06260219715470
Pubmed

Connexins 26 and 30 are co-assembled to form gap junctions in the cochlea of mice.

GJB2 GJB6

2.93e-06260212859965
Pubmed

Frequency and distribution of GJB2 (connexin 26) and GJB6 (connexin 30) mutations in a large North American repository of deaf probands.

GJB2 GJB6

2.93e-06260212865758
Pubmed

Genotyping for Cx26 and Cx30 mutations in cases with congenital hearing loss.

GJB2 GJB6

2.93e-06260218554165
Pubmed

Connexin gene mutations among Ugandan patients with nonsyndromic sensorineural hearing loss.

GJB2 GJB6

2.93e-06260224706568
Pubmed

GJB2 and GJB6 mutations in 165 Danish patients showing non-syndromic hearing impairment.

GJB2 GJB6

2.93e-06260215345117
Pubmed

Permeation pathway of homomeric connexin 26 and connexin 30 channels investigated by molecular dynamics.

GJB2 GJB6

2.93e-06260222292956
Pubmed

Connexin 26 and 30 genes mutations in patients with chronic rhinosinusitis.

GJB2 GJB6

2.93e-06260217989577
Pubmed

GJB2 and GJB6 screening in Tunisian patients with autosomal recessive deafness.

GJB2 GJB6

2.93e-06260223434199
Pubmed

Novel connexin 30 and connexin 26 mutational spectrum in patients with progressive sensorineural hearing loss.

GJB2 GJB6

2.93e-06260222704424
Pubmed

Low incidence of GJB2, GJB6 and mitochondrial DNA mutations in North Indian patients with non-syndromic hearing impairment.

GJB2 GJB6

2.93e-06260219465004
Pubmed

In vivo genetic manipulation of inner ear connexin expression by bovine adeno-associated viral vectors.

GJB2 GJB6

2.93e-06260228779115
Pubmed

Screening for monogenetic del(GJB6-D13S1830) and digenic del(GJB6-D13S1830)/GJB2 patterns of inheritance in deaf individuals from Eastern Austria.

GJB2 GJB6

2.93e-06260215464308
Pubmed

Prevalence of the GJB2 mutations and the del(GJB6-D13S1830) mutation in Brazilian patients with deafness.

GJB2 GJB6

2.93e-06260215464305
Pubmed

Connexin 26 and connexin 30 mutations in children with nonsyndromic hearing loss.

GJB2 GJB6

2.93e-06260215064611
InteractionRGPD2 interactions

RGPD4 RANGAP1 RGPD8 RGPD3 RGPD1 RGPD5

1.52e-1027606int:RGPD2
InteractionRGPD4 interactions

RGPD4 RGPD8 RGPD3 RGPD1 RGPD5

5.00e-0922605int:RGPD4
InteractionRGPD1 interactions

RGPD4 RANGAP1 RGPD8 RGPD3 RGPD1 RGPD5

6.82e-0949606int:RGPD1
InteractionRGPD5 interactions

RGPD4 RANGAP1 RGPD8 RGPD3 NR2E1 RGPD1 RGPD5

1.40e-0896607int:RGPD5
InteractionRGPD3 interactions

RGPD4 RGPD8 RGPD3 RGPD1 RGPD5

2.75e-0747605int:RGPD3
InteractionRGPD8 interactions

RGPD4 RGPD8 RGPD3 RGPD1 RGPD5

2.72e-0674605int:RGPD8
InteractionNPIPB6 interactions

RGPD8 RGPD1 RGPD5

1.98e-0518603int:NPIPB6
InteractionGJB6 interactions

GJB2 GPR61 GJB6

3.71e-0522603int:GJB6
InteractionRANBP2 interactions

RGPD4 RANGAP1 RGPD8 RGPD3 RGPD1 ALB RGPD5

9.54e-05361607int:RANBP2
Cytoband2q13

RGPD8 RGPD3 RGPD5

1.00e-04686032q13
CytobandEnsembl 112 genes in cytogenetic band chr13q12

GJB2 ATP8A2 GJB6 HSPH1

2.56e-04234604chr13q12
Cytoband13q12.3

PDS5B HSPH1

3.82e-042260213q12.3
Cytoband13q12

ATP8A2 GJB6

4.55e-042460213q12
CytobandEnsembl 112 genes in cytogenetic band chr2q12

RGPD4 RGPD3

5.22e-0382602chr2q12
Cytoband6q21

AMD1 NR2E1

7.08e-03966026q21
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

RGPD4 RGPD8 RGPD3 RGPD1 TTC5 RGPD5

3.86e-07115456769
GeneFamilyAcyl-CoA thioesterases

ACOT1 ACOT12

2.69e-041045241
GeneFamilySolute carriers

SLC25A21 SLC16A1 SLC4A10 SLC35B2 SLC25A25 SLC2A2

4.15e-04395456752
GeneFamilyATPase phospholipid transporting

ATP8B4 ATP8A2

6.23e-04154521210
GeneFamilyCadherin related

FAT1 CLSTN2

8.04e-041745224
GeneFamilyGap junction proteins

GJB2 GJB6

1.36e-0322452314
CoexpressionGAUSSMANN_MLL_AF4_FUSION_TARGETS_B_UP

RGPD4 RGPD8 RGPD3 RGPD1

9.66e-0733604MM477
CoexpressionTABULA_MURIS_SENIS_TRACHEA_GRANULOCYTE_AGEING

RGPD4 RGPD8 RGPD3 RGPD1

2.86e-0643604MM3857
CoexpressionAtlasFacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_1000_k-means-cluster#2

ACSL6 ABCA2 HSPH1 NR2E1 SCRN1 CLSTN2 ADGRV1 LFNG

4.10e-07248598Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_1000_K2
CoexpressionAtlasFacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_500_k-means-cluster#2

ACSL6 ABCA2 HSPH1 NR2E1 ADGRV1 LFNG

3.06e-06145596Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_500_K2
CoexpressionAtlasFacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#5

ACSL6 FAT1 ABCA2 HSPH1 NR2E1 SCRN1 CLSTN2 ADGRV1 LFNG IQCK

3.04e-057325910Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_2500_K5
CoexpressionAtlasFacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#2

ACSL6 FAT1 ABCA2 NR2E1 PAM SCRN1 CLSTN2 ADGRV1 SLC25A25 IQCK

3.61e-057475910Facebase_RNAseq_e9.5_Maxillary Arch_2500_K2
CoexpressionAtlasFacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_500_k-means-cluster#2

ACSL6 ABCA2 ADGRV1 LFNG

4.55e-0571594Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_500_K2
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_500

ACSL6 ABCA2 NR2E1 SCRN1 ADGRV1 BCOR LFNG IQCK

6.53e-05496598Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_500
CoexpressionAtlasFacebaseRNAseq_e9.5_Olfactory Placode_top-relative-expression-ranked_2500_k-means-cluster#4

ACSL6 FAT1 ABCA2 NR2E1 SCRN1 CLSTN2 ADGRV1 LFNG IQCK

1.04e-04683599Facebase_RNAseq_e9.5_Olfactory Placode_2500_K4
CoexpressionAtlasalpha beta T cells, preT.DN2.Th, Lin-/lo CD25hi CD44+ cKit+, Thymus, avg-3

ARHGAP32 PSAT1 ATP8B4 P2RX1 SLC16A1 DNA2 ITK

1.58e-04420597GSM791136_500
CoexpressionAtlasFacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_2500_k-means-cluster#5

ACSL6 FAT1 ABCA2 NR2E1 PAM SCRN1 CLSTN2 ADGRV1 IQCK

1.96e-04743599Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_2500_K5
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_500_k-means-cluster#3

ACSL6 SCRN1 ADGRV1 LFNG

2.32e-04108594Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_500_K3
CoexpressionAtlasFacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#5

ACSL6 ABCA2 ADGRV1 BCOR LFNG

2.62e-04205595Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_2500_K5
CoexpressionAtlasFacebaseRNAseq_e9.5_Olfactory Placode_top-relative-expression-ranked_1000_k-means-cluster#2

ABCA2 NR2E1 CLSTN2 ADGRV1 LFNG

2.93e-04210595Facebase_RNAseq_e9.5_Olfactory Placode_1000_K2
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_1000_k-means-cluster#3

ACSL6 SCRN1 CLSTN2 ADGRV1 BCOR LFNG

3.50e-04339596Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_1000_K3
CoexpressionAtlasFacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_1000_k-means-cluster#5

ACSL6 SCRN1 ADGRV1 IQCK

3.93e-04124594Facebase_RNAseq_e10.5_Medial Nasal Eminence_1000_K5
CoexpressionAtlasFacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_500

ACSL6 ABCA2 SLC16A1 HSPH1 NR2E1 ADGRV1 LFNG

3.99e-04489597Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_500
CoexpressionAtlasFacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_1000_k-means-cluster#1

ACSL6 ABCA2 ADGRV1 LFNG

4.31e-04127594Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_1000_K1
CoexpressionAtlasFacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_500

ACSL6 ABCA2 SLC16A1 HSPH1 ACOT1 ADGRV1 LFNG

4.34e-04496597Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_500
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500

ABCA2 HSPH1 NR2E1 SCRN1 ADGRV1 LFNG IQCK

4.45e-04498597Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500
CoexpressionAtlasFacebaseRNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_2500_k-means-cluster#5

ACSL6 FAT1 ABCA2 NR2E1 PAM SCRN1 CLSTN2 IQCK

4.48e-04658598Facebase_RNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_2500_K5
ToppCellBronchus_Control_(B.)-Epithelial-TX-AT2-2|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

SLC16A1 ATP8A2 MATN1 SLC25A25 RIC1

6.38e-061946055bfc26668fa8f109f2ebc0d5fd98ab5bd219e62c
ToppCellfacs-Brain_Non-Myeloid-Cortex|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACSL6 ARHGAP32 PSAT1 ABCA2 GJB6

6.70e-06196605256fe9bc0815f66a9afe11ba3507ef1372b52fd3
ToppCellICU-SEP-Lymphocyte-T_NK-Treg|ICU-SEP / Disease, Lineage and Cell Type

ATP8A2 GJB6 RGPD1 RGPD5

4.39e-05145604ee99b58462f955b96d036aa67e343db047d66f64
ToppCellCOVID-19_Severe-CD8+_T_naive|COVID-19_Severe / disease group, cell group and cell class

ACSL6 GJB6 ADGRV1 ITK

5.27e-05152604e6dbf20504c4fb73d1084b587e040855335b8959
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_3|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GJB6 RGPD3 RGPD1 ITK

5.41e-051536047480522a47e367f8facc4f5d599fbaf0b5ad4007
ToppCellCOVID-19_Severe-CD8+_T_naive|World / disease group, cell group and cell class

ACSL6 GJB6 ADGRV1 ITK

5.54e-05154604b568417d88a78d8c46688847f0f5f4989bd36387
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_3|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

GJB6 RGPD3 RGPD1 ITK

5.83e-0515660453ded973358e3e48054130131e959f0d1f4ef60f
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

TTC5 SLC25A25 RIC1 IQCK

6.28e-051596041472536eea61d4f13033efe42f128bae1614fa74
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Pericentral)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PSAT1 GJB2 SLC2A2 ACOT12

6.43e-05160604c42bcc6c7d113f0db43febb088b75ca4ac7cb7a3
ToppCelldroplet-Heart-nan-18m-Mesenchymal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP32 COL15A1 ALB ADGRV1

7.42e-051666049adceb746e67e955fd8b3e0984f4eed44b64a270
ToppCell5'-Adult-SmallIntestine-Hematopoietic-T_cells-SELL+_CD8_T|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SBK1 RANGAP1 HSPH1 MYCBPAP

7.95e-05169604cc1b60eb50a274ffd72c67082c19e43af775e949
ToppCellCOVID-19_Severe-Treg|COVID-19_Severe / disease group, cell group and cell class

SLC16A1 GJB6 RGPD3 ITK

8.13e-05170604d61269a51283125835884c4aa50623756c4fdda2
ToppCellControl-B_cells-Plasma_cells|Control / group, cell type (main and fine annotations)

PSAT1 P2RX1 RALGPS2 RIC1

9.10e-05175604fb23858cfce71509cafbe0d9728e678012ff2962
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PSAT1 GJB2 SLC2A2 ACOT12

9.10e-051756045c38d4b6c03473d841e6203a7efaa6dcb2d59386
ToppCell10x3'2.3-week_14-16-Lymphocytic_T-T_NK-NK_T_cell|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SBK1 RGPD4 SLC4A10 ITK

9.30e-05176604f0c01fc4f9c17c4d724642d9931731eef2b10258
ToppCelldroplet-Spleen-nan-3m-Lymphocytic-mature_NK_T_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP8B4 ATP8A2 LFNG ITK

9.51e-05177604dba8b30a311051c22ca5f77697f5dbf9423c3ba0
ToppCellCOPD-Lymphoid-T_Regulatory|World / Disease state, Lineage and Cell class

SLC16A1 RGPD1 PAM ITK

1.01e-0418060451a12fbad5fa7bb12e6d616a02ff9b5141e2b063
ToppCellMesenchymal_cells-Stromal_fibro.|Mesenchymal_cells / Lineage and Cell class

PSAT1 GJB2 COL15A1 ACOT1

1.04e-04181604f8d914fdc06aaa75a4dc9158daf574ca28fa5432
ToppCellCOPD-Lymphoid-B_Plasma|Lymphoid / Disease state, Lineage and Cell class

P2RX1 RALGPS2 RAPGEF1 RIC1

1.06e-0418260419db653fe04c5e2957eea1f4893b1c1fca4ddcbd
ToppCell10x3'2.3-week_12-13-Mesenchymal_osteo-stroma-chondrocyte|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

GJB2 COL15A1 MATN1 PAM

1.06e-04182604ed487f3a774812caa2903a646b60c86edcc1e65e
ToppCellfacs-Liver-Non-hepatocytes-3m-Lymphocytic-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PSAT1 ATP8A2 LFNG ITK

1.10e-041846048fc047977fad38fcd26eebcc279a688efd342ed8
ToppCellwk_20-22-Epithelial-PNS-intermediate_Schwann|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ABCA2 COL15A1 SCRN1 CLSTN2

1.10e-041846044e3ba64692868563a579902aa9c6f88cab5bce26
ToppCellfacs-Marrow-T-cells-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SBK1 RALGPS2 ALB ITK

1.13e-04185604e1fd0a807def8c2127194108b1a30c6de7024292
ToppCellCOPD-Lymphoid-T_Regulatory|COPD / Disease state, Lineage and Cell class

SLC16A1 RGPD1 PAM ITK

1.13e-04185604846403edd4c8f646201d519055198fc38b7ffff9
ToppCellfacs-Thymus-nan-3m-Lymphocytic-DN4_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SBK1 ALB LFNG ITK

1.13e-04185604a2cae8c657e4f4d121476798e424876f7e247973
ToppCellfacs-Thymus-nan-3m-Lymphocytic-DN4_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SBK1 ALB LFNG ITK

1.13e-04185604d50406a9a5b8d75110ba5985741aa2293950c543
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACSL6 GJB6 NR2E1 LFNG

1.15e-04186604ac7a84b11b4550c4ac01eab370dc8ab88e4fb72b
ToppCellCOVID-19-kidney-Stressed_PCT|kidney / Disease (COVID-19 only), tissue and cell type

PSAT1 ATP8B4 HSPH1 SLC2A2

1.17e-04187604acd305475f3609800af0d7bc68d83ef41228080b
ToppCellCOVID-19-lung-Plasma_cells_PRDM1/BLIMP_int|COVID-19 / Disease (COVID-19 only), tissue and cell type

PSAT1 P2RX1 HSPH1 RALGPS2

1.20e-04188604599195338070ac6b79bd114609d9e10cac4f1df4
ToppCellwk_15-18-Hematologic-Myeloid-Basophil|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ABCA2 P2RX1 PGBD4 LFNG

1.20e-041886043638d85452de15a060146628fbbad9d2a36feb13
ToppCell(02)_Cycling_Basal_(regeneration)-(1)_24hpi|(02)_Cycling_Basal_(regeneration) / shred by cell type and Timepoint

AMD1 PSAT1 RANGAP1 HSPH1

1.22e-04189604311f3aed469be3c8ff913dcc5a2442daa8446d55
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FAT1 MYOM3 CLSTN2 SLC2A2

1.22e-0418960428b502611829e4a24caff2562545c7db97686099
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACSL6 GJB6 NR2E1 LFNG

1.27e-04191604fd345837bfc40d85256b9a7e4fd3343bcbfe0ae5
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Immune|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ATP8B4 P2RX1 RAPGEF1 ITK

1.27e-04191604468b5149d1533f03521844d3cce8633d44eb6ed4
ToppCellParenchymal-10x3prime_v2-Immune_Lymphocytic-T-T_CD4-T_reg|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

GPR61 GJB6 PGBD4 ITK

1.30e-0419260494e11f68767a899cbcc6984f9398877c1e464abc
ToppCellChildren_(3_yrs)-Immune-natural_killer_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

SBK1 ABCA2 ATP8B4 ITK

1.33e-041936041cb666375bc4e1b11a146d20896c9b5ae6fd0887
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP32 PSAT1 ABCA2 SCRN1

1.35e-04194604ba529c051f248d29f4222f4bc9801ba233859093
ToppCellsevere-Myeloid-CD16_Monocytes|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

HSPH1 SCRN1 SLC25A25 LFNG

1.38e-041956045badcfdeed2fb7453a9c144506ca91c5475cd35f
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ARHGAP32 HSPH1 SLC4A10 CLSTN2

1.38e-041956042e1df01bf6e4e98e6cd9fb50926e34c5077b8666
ToppCell10x3'2.3-week_17-19-Lymphocytic_B-B_lineage-immature_B_cell|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

AMD1 HSPH1 RALGPS2 LFNG

1.41e-041966049a6e4eea19348a6e3379d3b872456ab6280cb74f
ToppCellNon-neuronal-Non-dividing-Radial_Glia-tRG|World / Primary Cells by Cluster

PSAT1 NR2E1 SCRN1 ADGRV1

1.44e-0419760461749ccafeb938c310cff1de5ff924a1c794325a
ToppCellBronchial-NucSeq-Immune_Lymphocytic-B-B_plasma-B_plasma_IgA|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

P2RX1 RALGPS2 RGPD1 RAPGEF1

1.44e-04197604749e0e332644543cbdf2ee38c2b301ce0a019a7f
ToppCellNon-neuronal-Non-dividing-Radial_Glia-tRG-25|World / Primary Cells by Cluster

PSAT1 NR2E1 SCRN1 ADGRV1

1.44e-041976049d4ffa3680f92c91d0a081f9a8ec5ebfec6bdcf6
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACSL6 PSAT1 ABCA2 GJB6

1.46e-04198604a7e5de81eb7d3d23812c179a001adbaab1506596
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ARHGAP32 ATP8A2 SLC4A10 PAM

1.46e-041986048ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCellParenchymal-10x3prime_v2-Immune_Lymphocytic-T-T_CD8-MAIT|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

MYOM3 SLC4A10 ZFP92 ITK

1.46e-04198604f26150ae3fee6b2df2a51efaefbcfeb27f725a65
ToppCellBronchial-NucSeq-Immune_Myeloid-Monocytic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ATP8B4 P2RX1 RAPGEF1 LFNG

1.52e-042006048872d5fa101d413fb43b4231d476878678543035
ToppCellParenchymal-NucSeq-Immune_Lymphocytic-T-T_CD8-gdT|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

GJB2 ABCA2 ATP8B4 ITK

1.52e-042006041779a8ff4443a85ac500f849764e86d9c7529b84
ToppCellSepsis-Int-URO-Lymphocyte-T/NK-MAIT|Int-URO / Disease, condition lineage and cell class

MATN1 SLC4A10 MYCBPAP RGPD5

1.52e-04200604043c18e79a969e37bbff86443e553ac09fe33f84
Diseaseautosomal recessive nonsyndromic deafness 1A (implicated_via_orthology)

GJB2 GJB6

3.41e-062552DOID:0110475 (implicated_via_orthology)
DiseaseKeratitis-Ichthyosis-Deafness Syndrome

GJB2 GJB6

3.41e-062552C3665333
DiseaseDFNA 3 Nonsyndromic Hearing Loss and Deafness

GJB2 GJB6

3.41e-062552cv:CN043589
DiseaseSenter syndrome

GJB2 GJB6

3.41e-062552C0265336
Diseaseautosomal recessive nonsyndromic deafness 1A (is_implicated_in)

GJB2 GJB6

3.41e-062552DOID:0110475 (is_implicated_in)
DiseaseDeafness, autosomal dominant nonsyndromic sensorineural 3

GJB2 GJB6

1.02e-053552cv:
DiseaseProgressive hearing loss stapes fixation

GJB2 GJB6

1.02e-053552C1844678
DiseaseDEAFNESS, AUTOSOMAL RECESSIVE 1A

GJB2 GJB6

1.02e-053552220290
DiseaseDEAFNESS, DIGENIC, GJB2/GJB6 (disorder)

GJB2 GJB6

1.02e-053552C2673760
DiseaseDEAFNESS, DIGENIC, GJB2/GJB3 (disorder)

GJB2 GJB6

1.02e-053552C2673761
DiseaseDEAFNESS, AUTOSOMAL RECESSIVE 1A (disorder)

GJB2 GJB6

1.02e-053552C2673759
DiseaseX-linked mixed hearing loss with perilymphatic gusher

GJB2 GJB6

1.02e-053552cv:C1844678
DiseaseDEAFNESS, X-LINKED 2

GJB2 GJB6

1.02e-053552304400
DiseaseAutosomal recessive nonsyndromic hearing loss 1A

GJB2 GJB6

1.02e-053552cv:C2673759
DiseaseHidrotic Ectodermal Dysplasia

GJB2 GJB6

3.40e-055552C0162361
Diseasefish oil supplement exposure measurement, triglyceride measurement

GJB2 GJB6

1.52e-0410552EFO_0004530, EFO_0600007
Diseasehearing impairment

GJB2 GJB6 ADGRV1

8.22e-0498553C1384666
Diseaseresponse to methotrexate, drug-induced liver injury

ATP8A2 BCOR

1.08e-0326552EFO_0004228, GO_0031427
DiseaseAutosomal dominant nonsyndromic hearing loss

GJB2 GJB6

1.34e-0329552cv:C5779548

Protein segments in the cluster

PeptideGeneStartEntry
KSFIPVERAESTFLF

ACOT1

306

Q86TX2
RFPKAEFAEVSKLVT

ALB

246

P02768
AFADVSVKFKAVPIT

ADGRV1

2146

Q8WXG9
EKLVSVAFSTFVAKP

ACOT12

101

Q8WYK0
FRSPLSVFKRFKETT

PAM

21

P19021
FGFIFKSRTPETITI

ATP8B4

506

Q8TF62
FVSRPTEKTVFTVFM

GJB2

181

P29033
VTLFPDIKIVSTFAK

CLSTN2

656

Q9H4D0
FKQPVFTVSKDSVLA

BCOR

871

Q6W2J9
EFVSASFDKSIRIFP

DCAF13

296

Q9NV06
KKLGFVFTARTPFSV

ATP8A2

536

Q9NTI2
PEKVVSAFLKVSSVF

RANGAP1

466

P46060
FAAPLKSLVATFIVK

PDS5B

781

Q9NTI5
IKPVFDFLVNKFSTV

PGBD4

226

Q96DM1
PKFVFVSESVKRIFS

RGPD5

1536

Q99666
PKFVFVSESVKRIFS

RGPD8

1536

O14715
TVAKFITEFPLFLQT

RIC1

886

Q4ADV7
FTEFFSIPFVEERLK

IQCK

186

Q8N0W5
FIEPKTGVVSSKRFS

FAT1

1301

Q14517
FPKSITVFFKEIEGI

SLC16A1

36

P53985
LAETPKRAVKFFTFE

SLC25A21

81

Q9BQT8
VIAKTPALRKFVFVF

GPR61

66

Q9BZJ8
APRDVFIAVKTTKKF

LFNG

111

Q8NES3
SVRPVEFEKVKVFLS

MATN1

51

P21941
VPSSFSPFVEFKEKT

NFRKB

441

Q6P4R8
AFKVREFSVTDAVPF

HSPH1

386

Q92598
FTLFTFFKVPETKGK

SLC2A2

476

P11168
TSVFVVDPKESFVKA

MYH1

36

P12882
LRVIAEKKFFTVSPE

PCDHGB3

66

Q9Y5G1
SSFTEKVVYAFSPKI

ARHGAP32

881

A7KAX9
VKRIFSSEKSKPFAF

RGPD3

1546

A6NKT7
FISRPTEKTVFTIFM

GJB6

181

O95452
VVEVFKPGKFVTTLF

AMD1

271

P17707
IAAVQKVSPTFFFLR

DDX12P

911

Q92771
PASFVVFLVAEKSTK

ABCA2

1806

Q9BZC7
STPFHIFKVKVTTER

HORMAD1

216

Q86X24
TFFRDFAISVVVKPS

COL15A1

86

P39059
EIFITFRVQKSPVFR

DNAJA3

326

Q96EY1
FQKKVVASFPRTVLS

DNA2

26

P51530
SSPFIIKVFDVVFET

SBK1

106

Q52WX2
RSISPSTIEEVFFKK

NR2E1

351

Q9Y466
PKFVFGSESVKRIFS

RGPD1

1521

P0DJD0
KSFDAVVFDVLKVTP

RALGPS2

36

Q86X27
TSPSNFKVRFFVLTK

ITK

21

Q08881
TLFIKNSISFPRFKV

P2RX1

186

P51575
VKRIFSSEKSKPFAF

RGPD4

1546

Q7Z3J3
ITIKDFLKTFSPDVF

CARS2

326

Q9HA77
FLSKPVDVSKFGVIF

PSAT1

181

Q9Y617
SRSIFKPFIFVDDVK

SCRN1

301

Q12765
DFSGFLKVTEKVIFP

ACSL6

296

Q9UKU0
KSIFKLSVFIPSQEF

SLC25A25

31

Q6KCM7
VTGFIPTKFLSDKVV

SUPT6H

1236

Q7KZ85
KVPVSFEDVSVYFTK

ZFP92

11

A6NM28
EKFSPFADTFKKRVS

RAPGEF1

741

Q13905
FVSFPTQVLAKASKV

SLC35B2

206

Q8TB61
FKTSRYFPTKVRSIV

SLC4A10

746

Q6U841
VVFSLTTEEKVPFTF

TTC5

341

Q8N0Z6
ILPGEIKTFTFFFKS

MYCBPAP

491

Q8TBZ2
TGLKVVSKRPEFFTF

TRAPPC8

946

Q9Y2L5
VEFTSVLKPVFAREK

MYOM3

271

Q5VTT5