Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessWnt receptor catabolic process

ZNRF3 RNF43

1.30e-052752GO:0038018
GeneOntologyBiologicalProcessregulation of platelet formation

MPL CSF1R

3.90e-053752GO:1905219
DomainGrowth_fac_rcpt_

FRAS1 EGFR SUSD1 PCSK6 GAS6 LAMA1 ELAPOR1 LRP2 ADGRE5 LTBP2 VWCE STAB1

1.25e-121567512IPR009030
DomainEGF-like_dom

FRAS1 TENM4 SUSD1 PCSK6 GAS6 LAMA1 ADGRE4P LRP2 ADGRE5 LTBP2 VWCE OTOG STAB1

1.87e-112497513IPR000742
DomainEGF

FRAS1 TENM4 SUSD1 PCSK6 GAS6 LAMA1 ADGRE4P LRP2 ADGRE5 LTBP2 VWCE STAB1

1.54e-102357512SM00181
DomainEGF_3

TENM4 SUSD1 GAS6 ADGRE4P LRP2 ADGRE5 LTBP2 VWCE OTOG STAB1

3.33e-082357510PS50026
DomainEGF-like_Ca-bd_dom

SUSD1 GAS6 ADGRE4P LRP2 ADGRE5 LTBP2 VWCE STAB1

3.50e-08124758IPR001881
DomainEGF_CA

SUSD1 GAS6 ADGRE4P LRP2 ADGRE5 LTBP2 VWCE

5.28e-0886757PF07645
DomainEGF_CA

SUSD1 GAS6 ADGRE4P LRP2 ADGRE5 LTBP2 VWCE

1.40e-0799757PS01187
DomainASX_HYDROXYL

SUSD1 GAS6 ADGRE4P LRP2 ADGRE5 LTBP2 VWCE

1.50e-07100757PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

SUSD1 GAS6 ADGRE4P LRP2 ADGRE5 LTBP2 VWCE

2.24e-07106757IPR000152
DomainEGF_CA

SUSD1 GAS6 LRP2 ADGRE5 LTBP2 VWCE STAB1

5.86e-07122757SM00179
DomainEGF_1

TENM4 SUSD1 GAS6 LAMA1 LRP2 LTBP2 VWCE USH2A STAB1

8.20e-07255759PS00022
DomainEGF_Ca-bd_CS

SUSD1 GAS6 LRP2 ADGRE5 LTBP2 VWCE

2.53e-0697756IPR018097
DomainEGF-like_CS

TENM4 SUSD1 GAS6 LAMA1 LRP2 LTBP2 VWCE STAB1

9.82e-06261758IPR013032
DomainEGF_2

TENM4 SUSD1 GAS6 LAMA1 LRP2 LTBP2 VWCE STAB1

1.10e-05265758PS01186
DomainTF_homeodomain_male

PHTF2 PHTF1

1.59e-052752IPR021980
DomainPhtf-FEM1B_bdg

PHTF2 PHTF1

1.59e-052752PF12129
Domain-

COL16A1 GAS6 LAMA1 USH2A ADGRG6

3.99e-05957552.60.120.200
DomainFurin_repeat

FRAS1 EGFR PCSK6

4.86e-0518753IPR006212
DomainFU

FRAS1 EGFR PCSK6

4.86e-0518753SM00261
DomainVWC_out

FRAS1 VWCE OTOG

5.75e-0519753SM00215
DomainLaminin_G

COL16A1 GAS6 LAMA1 USH2A

8.63e-0558754IPR001791
DomainEGF_extracell

TENM4 LRP2 LTBP2 STAB1

9.86e-0560754IPR013111
DomainEGF_2

TENM4 LRP2 LTBP2 STAB1

9.86e-0560754PF07974
Domainzf-RING_9

DEF8 PLEKHM3

1.58e-045752PF13901
DomainDUF4206

DEF8 PLEKHM3

1.58e-045752SM01175
DomainZf-RING_9

DEF8 PLEKHM3

1.58e-045752IPR025258
DomainEGF_LAM_2

LAMA1 USH2A STAB1

2.34e-0430753PS50027
DomainEGF_LAM_1

LAMA1 USH2A STAB1

2.34e-0430753PS01248
DomainGF_recep_IV

EGFR PCSK6

2.36e-046752PF14843
DomainGF_recep_IV

EGFR PCSK6

2.36e-046752IPR032778
DomainGPS

ADGRE4P ADGRE5 ADGRG6

3.40e-0434753SM00303
DomainGPS

ADGRE4P ADGRE5 ADGRG6

3.71e-0435753PF01825
DomainLaminin_EGF

LAMA1 USH2A STAB1

3.71e-0435753PF00053
DomainEGF_Lam

LAMA1 USH2A STAB1

3.71e-0435753SM00180
DomainGPS

ADGRE4P ADGRE5 ADGRG6

4.04e-0436753PS50221
DomainGPS

ADGRE4P ADGRE5 ADGRG6

4.38e-0437753IPR000203
DomainLAM_G_DOMAIN

GAS6 LAMA1 USH2A

4.74e-0438753PS50025
DomainLaminin_EGF

LAMA1 USH2A STAB1

4.74e-0438753IPR002049
DomainWD40_repeat_CS

APAF1 WDR83 WDR90 WDR77 WDR59

5.16e-04164755IPR019775
DomainLaminin_G_2

GAS6 LAMA1 USH2A

5.52e-0440753PF02210
DomainVWF_dom

FRAS1 VWCE OTOG

6.38e-0442753IPR001007
DomainLamG

GAS6 LAMA1 USH2A

7.32e-0444753SM00282
Domain-

SUSD1 STAB1

8.55e-04117522.40.155.10
DomainGFP-like

SUSD1 STAB1

8.55e-0411752IPR023413
DomainLaminin_G_1

GAS6 LAMA1

8.55e-0411752PF00054
DomainG_PROTEIN_RECEP_F2_2

ADGRE4P ADGRE5 ADGRG6

1.06e-0350753PS00650
Domain7tm_2

ADGRE4P ADGRE5 ADGRG6

1.06e-0350753PF00002
DomainTIL_dom

LRP2 OTOG

1.40e-0314752IPR002919
DomainEGF

GAS6 LRP2 LTBP2 STAB1

1.66e-03126754PF00008
DomainGPCR_2_secretin-like

ADGRE4P ADGRE5 ADGRG6

1.81e-0360753IPR000832
DomainLaminin_N

LAMA1 USH2A

1.84e-0316752IPR008211
DomainLAMININ_NTER

LAMA1 USH2A

1.84e-0316752PS51117
DomainLaminin_N

LAMA1 USH2A

1.84e-0316752PF00055
DomainLamNT

LAMA1 USH2A

1.84e-0316752SM00136
DomainConA-like_dom

COL16A1 GAS6 LAMA1 USH2A ADGRG6

1.88e-03219755IPR013320
DomainG_PROTEIN_RECEP_F2_4

ADGRE4P ADGRE5 ADGRG6

1.89e-0361753PS50261
Domain-

SERGEF TECPR1

3.49e-03227522.130.10.30
DomainRCC1/BLIP-II

SERGEF TECPR1

3.81e-0323752IPR009091
DomainWD40

APAF1 WDR83 WDR90 WDR77 WDR59

3.87e-03259755PF00400
Pubmed

Receptor Elimination by E3 Ubiquitin Ligase Recruitment (REULR): A Targeted Protein Degradation Toolbox.

EGFR ZNRF3 RNF43

6.27e-07879337011906
Pubmed

RNF43 and ZNRF3 are commonly altered in serrated pathway colorectal tumorigenesis.

ZNRF3 RNF43

5.09e-06279227661107
Pubmed

Upregulation of APAF1 and CSF1R in Peripheral Blood Mononuclear Cells of Parkinson's Disease.

CSF1R APAF1

5.09e-06279237108258
Pubmed

ZNRF3 and RNF43 cooperate to safeguard metabolic liver zonation and hepatocyte proliferation.

ZNRF3 RNF43

5.09e-06279234129813
Pubmed

E3 ligases RNF43 and ZNRF3 display differential specificity for endocytosis of Frizzled receptors.

ZNRF3 RNF43

5.09e-06279238969364
Pubmed

EGFR is required for Wnt9a-Fzd9b signalling specificity in haematopoietic stem cells.

EGFR WNT9A

5.09e-06279231110287
Pubmed

RNF43/ZNRF3 loss predisposes to hepatocellular-carcinoma by impairing liver regeneration and altering the liver lipid metabolic ground-state.

ZNRF3 RNF43

5.09e-06279235039505
Pubmed

Reticulon 3-dependent ER-PM contact sites control EGFR nonclathrin endocytosis.

EGFR RTN3

5.09e-06279228495747
Pubmed

Molecular characterization of a novel gene family (PHTF) conserved from Drosophila to mammals.

PHTF2 PHTF1

5.09e-06279210729229
Pubmed

RNF43/ZNRF3 negatively regulates taste tissue homeostasis and positively regulates dorsal lingual epithelial tissue homeostasis.

ZNRF3 RNF43

1.53e-05379234995498
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

TMEM201 ATG2B DEF8 LRP2 RTN3 PLEKHM3 HEATR5B WDR59

1.95e-0550479834432599
Pubmed

Porcupine inhibitor suppresses paracrine Wnt-driven growth of Rnf43;Znrf3-mutant neoplasia.

ZNRF3 RNF43

3.05e-05479226023187
Pubmed

Microglial stimulation of glioblastoma invasion involves epidermal growth factor receptor (EGFR) and colony stimulating factor 1 receptor (CSF-1R) signaling.

CSF1R EGFR

3.05e-05479222294205
Pubmed

Dishevelled promotes Wnt receptor degradation through recruitment of ZNRF3/RNF43 E3 ubiquitin ligases.

ZNRF3 RNF43

3.05e-05479225891077
Pubmed

Customized treatment in non-small-cell lung cancer based on EGFR mutations and BRCA1 mRNA expression.

UIMC1 EGFR

3.05e-05479219415121
Pubmed

Non-enzymatic developmental functions of acetylcholinesterase--the question of redundancy.

GAS6 LAMA1

3.05e-05479218785927
Pubmed

SH2 domains of the p85 alpha subunit of phosphatidylinositol 3-kinase regulate binding to growth factor receptors.

CSF1R EGFR

3.05e-0547921372092
Pubmed

Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors.

ZNRF3 RNF43

3.05e-05479222895187
Pubmed

Expression and characterization of the p85 subunit of the phosphatidylinositol 3-kinase complex and a related p85 beta protein by using the baculovirus expression system.

CSF1R EGFR

5.07e-0557921334406
Pubmed

LGR4 and LGR5 form distinct homodimers that only LGR4 complexes with RNF43/ZNRF3 to provide high affinity binding of R-spondin ligands.

ZNRF3 RNF43

5.07e-05579237402772
Pubmed

Clearance of apoptotic cells is not impaired in mouse embryos deficient in class A scavenger receptor types I and II (CD204).

MSR1 CSF1R

5.07e-05579215580571
Pubmed

International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors.

ADGRE4P ADGRE5 ADGRG6

5.86e-053379325713288
Pubmed

The EGF-TM7 family: a postgenomic view.

ADGRE4P ADGRE5

7.60e-05679214647991
Pubmed

Structural and molecular basis of ZNRF3/RNF43 transmembrane ubiquitin ligase inhibition by the Wnt agonist R-spondin.

ZNRF3 RNF43

7.60e-05679224225776
Pubmed

Tyrosine phosphorylation and translocation of the c-cbl protein after activation of tyrosine kinase signaling pathways.

CSF1R EGFR

7.60e-0567927782294
Pubmed

Morphophenotypic characteristics of intralymphatic cancer and stromal cells susceptible to lymphogenic metastasis.

MSR1 EGFR

7.60e-05679222429811
Pubmed

Fat depot-specific mRNA expression of novel loci associated with waist-hip ratio.

ZNRF3 STAB1

7.60e-05679223670221
Pubmed

A ZNRF3-dependent Wnt/β-catenin signaling gradient is required for adrenal homeostasis.

ZNRF3 RNF43

1.06e-04779230692207
Pubmed

There exist at least 30 human G-protein-coupled receptors with long Ser/Thr-rich N-termini.

ADGRE4P ADGRG6

1.06e-04779212565841
Pubmed

USP42 protects ZNRF3/RNF43 from R-spondin-dependent clearance and inhibits Wnt signalling.

ZNRF3 RNF43

1.06e-04779233786993
Pubmed

A focused and efficient genetic screening strategy in the mouse: identification of mutations that disrupt cortical development.

LRP2 PCNT

1.06e-04779215314648
Pubmed

NOTUM from Apc-mutant cells biases clonal competition to initiate cancer.

ZNRF3 RNF43

1.41e-04879234079124
Pubmed

CSF-1 stimulation induces the formation of a multiprotein complex including CSF-1 receptor, c-Cbl, PI 3-kinase, Crk-II and Grb2.

CSF1R RAPGEF1

1.41e-0487929178909
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

TENM4 ZNRF3 APAF1 PCNT STAB1

1.66e-0422579512168954
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

FAM193B FRAS1 ZNRF3 OBSCN RAPGEF1 WDR90 RNF43 WDR59 ZNF426 PCNT

1.99e-041105791035748872
Pubmed

Differentiation of the mononuclear phagocyte system during mouse embryogenesis: the role of transcription factor PU.1.

MSR1 CSF1R

2.27e-041079210381505
Pubmed

Syntaxin 3 and Munc-18-2 in epithelial cells during kidney development.

LAMA1 LRP2

2.27e-041079210469351
Pubmed

Sequence-specific recognition of a PxLPxI/L motif by an ankyrin repeat tumbler lock.

MPL LRP2

2.76e-041179222649097
Pubmed

ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner.

ZNRF3 RNF43

2.76e-041179222575959
Pubmed

Apaf1-deficient cortical neurons exhibit defects in axonal outgrowth.

APAF1 PCNT

3.31e-041279225975226
Pubmed

RSPO2 inhibition of RNF43 and ZNRF3 governs limb development independently of LGR4/5/6.

ZNRF3 RNF43

3.31e-041279229769720
Pubmed

Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins.

FAM193B WDR90 WDR59

4.06e-046379311572484
Pubmed

Genetic mutations associated with cigarette smoking in pancreatic cancer.

MPL CSF1R EGFR

4.06e-046379319351817
Pubmed

Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.

TENM4 ELAPOR1 HEATR5B TECPR1

4.19e-0415379410718198
Pubmed

Fli-1 is required for murine vascular and megakaryocytic development and is hemizygously deleted in patients with thrombocytopenia.

MPL CSF1R

4.55e-041479210981960
Pubmed

ZNRF3 functions in mammalian sex determination by inhibiting canonical WNT signaling.

ZNRF3 RNF43

5.25e-041579229735715
Pubmed

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.

FRAS1 COL16A1 LAMA1 LTBP2

5.82e-0416779422159717
Pubmed

Breakdown of the reciprocal stabilization of QBRICK/Frem1, Fras1, and Frem2 at the basement membrane provokes Fraser syndrome-like defects.

FRAS1 LAMA1

5.99e-041679216880404
Pubmed

Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?

UIMC1 ZNF792 ECE2 OTOG

6.22e-0417079423314748
Pubmed

G-protein-coupled receptor-mediated activation of rap GTPases: characterization of a novel Galphai regulated pathway.

EGFR RAPGEF1

7.61e-041879214712229
Pubmed

Generalist genes analysis of DNA markers associated with mathematical ability and disability reveals shared influence across ages and abilities.

FRAS1 TENM4

7.61e-041879220602751
Pubmed

A comprehensive genetic map of murine chromosome 11 reveals extensive linkage conservation between mouse and human.

CSF1R EGFR

7.61e-04187922567264
Pubmed

A direct functional link between the multi-PDZ domain protein GRIP1 and the Fraser syndrome protein Fras1.

FRAS1 LAMA1

7.61e-041879214730302
Pubmed

Apoptotic cells in mouse blastocysts are eliminated by neighbouring blastomeres.

MSR1 STAB1

7.61e-041879233927296
Pubmed

Functional genomics analysis identifies loss of HNF1B function as a cause of Mayer-Rokitansky-Küster-Hauser syndrome.

WNT9A LAMA1

7.61e-041879236282544
Pubmed

Human chromosome 11 DNA sequence and analysis including novel gene identification.

ZP1 TENM4 ZNF705EP

8.17e-048079316554811
Pubmed

Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.

LRP2 RAPGEF1 ADGRE5 LTBP2 F2RL2

9.34e-0432979517474147
Pubmed

Furin is the primary in vivo convertase of angiopoietin-like 3 and endothelial lipase in hepatocytes.

EGFR PCSK6

9.43e-042079223918928
Pubmed

The RSPO-LGR4/5-ZNRF3/RNF43 module controls liver zonation and size.

ZNRF3 RNF43

1.04e-032179227088858
Pubmed

CUEDC2, a novel interacting partner of the SOCS1 protein, plays important roles in the leukaemogenesis of acute myeloid leukaemia.

MPL CSF1R EGFR

1.04e-038779329991678
Pubmed

Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags.

EGFR ZNF792 ELAPOR1 WDR83 ADGRE5 MCOLN3

1.09e-0351079616712791
Pubmed

Characterization of 458 single nucleotide polymorphisms of disease candidate genes in the Korean population.

EGFR LRP2

1.14e-032279212768436
Pubmed

A systematic survey of loss-of-function variants in human protein-coding genes.

COL16A1 GEN1

1.14e-032279222344438
Pubmed

EMX2-GPR156-Gαi reverses hair cell orientation in mechanosensory epithelia.

GPR156 PCNT

1.14e-032279234001891
Pubmed

Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.

LAMA1 LRP2 PHTF1 OTOG

1.32e-0320879433230847
Pubmed

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.

ZNRF3 STAB1

1.36e-032479220935629
Pubmed

DCAF8, a novel MuRF1 interaction partner, promotes muscle atrophy.

SHFL ELAPOR1 DEF8 PCGF3 DNASE1L1

1.46e-0336479531391242
Pubmed

Global genetic analysis in mice unveils central role for cilia in congenital heart disease.

FRAS1 PCSK6 LRP2

1.56e-0310079325807483
Pubmed

PTEN dephosphorylates Abi1 to promote epithelial morphogenesis.

LAMA1 PCNT

1.60e-032679232673396
Pubmed

Protein interactome reveals converging molecular pathways among autism disorders.

ZNRF3 RTN3 VWCE WDR59 RUSC2 STAB1

1.75e-0356079621653829
Pubmed

Genetic link between renal birth defects and congenital heart disease.

FRAS1 LRP2

1.85e-032879227002738
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

IL17REL EGFR GAS6 OBSCN RTN3 PCGF3 ZMAT1 DNAH14 ADGRG6 PCNT

1.97e-031489791028611215
Pubmed

The human and mouse repertoire of the adhesion family of G-protein-coupled receptors.

ADGRE4P ADGRG6

1.99e-032979215203201
Pubmed

Basement membrane assembly of the integrin α8β1 ligand nephronectin requires Fraser syndrome-associated proteins.

FRAS1 LAMA1

1.99e-032979222613833
Pubmed

R-spondin signalling is essential for the maintenance and differentiation of mouse nephron progenitors.

ZNRF3 RNF43

2.13e-033079232324134
Pubmed

TBX1 is required for normal stria vascularis and semicircular canal development.

OTOG STAB1

2.27e-033179231550482
GeneFamilyCD molecules|Adhesion G protein-coupled receptors, subfamily E

ADGRE4P ADGRE5

6.58e-055472915
GeneFamilyWD repeat domain containing

APAF1 WDR83 WDR90 WDR77 WDR59

5.74e-04262475362
GeneFamilyC2-set domain containing|Immunoglobulin like domain containing|Scavenger receptors

MSR1 STAB1

2.23e-03274721253
GeneFamilyRing finger proteins

ZNRF3 RNF19B PCGF3 RNF43

5.59e-0327547458
GeneFamilyFibronectin type III domain containing

MPL OBSCN USH2A

8.29e-03160473555
GeneFamilyADAM metallopeptidase domain containing|CD molecules

MPL MSR1 CSF1R ADGRE5

1.90e-02394474471
CoexpressionNABA_ECM_GLYCOPROTEINS

ZP1 FRAS1 GAS6 LAMA1 LTBP2 VWCE USH2A OTOG

1.03e-07196768M3008
CoexpressionNABA_CORE_MATRISOME

ZP1 FRAS1 COL16A1 GAS6 LAMA1 LTBP2 VWCE USH2A OTOG

1.04e-07275769M5884
CoexpressionNABA_CORE_MATRISOME

ZP1 FRAS1 COL16A1 GAS6 LAMA1 LTBP2 VWCE OTOG

1.18e-06270768MM17057
CoexpressionMARKEY_RB1_CHRONIC_LOF_DN

MSR1 CSF1R EGFR RNF19B CFP STAB1

1.37e-06120766M5686
CoexpressionNABA_ECM_GLYCOPROTEINS

ZP1 FRAS1 GAS6 LAMA1 LTBP2 VWCE OTOG

1.40e-06191767MM17059
CoexpressionMARKEY_RB1_CHRONIC_LOF_DN

MSR1 CSF1R EGFR RNF19B CFP STAB1

2.18e-06130766MM975
CoexpressionGSE27786_CD8_TCELL_VS_NKCELL_DN

RNF19B LRP2 PHTF2 RTN3 CFP PLEKHM3

2.57e-05200766M4838
CoexpressionNABA_MATRISOME

ZP1 FRAS1 COL16A1 CCL28 PCSK6 WNT9A GAS6 LAMA1 LTBP2 VWCE USH2A OTOG

3.73e-0510267612M5889
CoexpressionNABA_MATRISOME_METASTATIC_LUNG_LYMPH_NODE_METASTASIS

COL16A1 LAMA1 LTBP2

8.11e-0529763MM17055
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 TENM4 LAMA1 OBSCN LRP2 USH2A OTOG

3.86e-081847972cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 TENM4 LAMA1 OBSCN LRP2 USH2A OTOG

3.86e-08184797ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 TENM4 LAMA1 OBSCN LRP2 USH2A OTOG

3.86e-081847972b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Aorta-Heart-18m-Myeloid-professional_antigen_presenting_cell|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MSR1 CSF1R SUSD1 SERGEF RNF43 MCOLN3

4.44e-07162796a6c6b953156c2e393d6ef5c3228eae90c472dda6
ToppCellPND07-28-samps-Myeloid-Macrophage-CD163+_Macrophage|PND07-28-samps / Age Group, Lineage, Cell class and subclass

MSR1 CSF1R SUSD1 GAS6 CFP STAB1

6.31e-071727969a659442dc41bd2a4361a7e38a7ee37a39781667
ToppCellhuman_hepatoblastoma-Tumor_cells|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

FRAS1 ZNRF3 PCSK6 RNF43 WDR59 DNAH14

1.24e-06193796503a979328c68b096680b71359a26f02fafdff35
ToppCellMonocytes-M2-like_CD16+_macrophages|World / Immune cells in Kidney/Urine in Lupus Nephritis

MSR1 CSF1R GAS6 LTBP2 ADGRG6 STAB1

1.31e-0619579610fa47bdcf6c9784ea930b75a5861e139421feed
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_alveolar-Macro_alv_MT|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MSR1 TENM4 CSF1R ADGRE5 VWCE STAB1

1.43e-061987962b724d2a36843801984d46a969d33149b76c9771
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c4-CD14-CD16|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

CSF1R ZNRF3 CDH19 RUSC2 STAB1

6.67e-06148795fd0d8386b94adb1bdc993fbb44d2d87852bfd7f0
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL16A1 TENM4 SHFL WNT9A LTBP2

1.03e-051627953f264263878af630921911c2b344ac56eb1e7099
ToppCellfacs-MAT-Fat-3m-Myeloid-myeloid_cell|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MSR1 CSF1R ADGRE4P CFP STAB1

1.07e-051637955fc836444bc156c8248abee001b0ecbe43f980c9
ToppCell368C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

MSR1 CSF1R GAS6 ADGRG6 STAB1

1.07e-051637954b8abbad4df040c895e3afb240759ebbc66b4d0e
ToppCellfacs-Aorta-Heart-18m-Myeloid|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MSR1 CSF1R SUSD1 RNF43 MCOLN3

1.07e-05163795ae9dd2daf06ad0b78f666617f6b070ec3ecc13d8
ToppCellfacs-Aorta-Heart-18m-Myeloid-nan|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MSR1 CSF1R SUSD1 RNF43 MCOLN3

1.07e-05163795ee94242a048fc62b85be85eca2442e13553cbfb7
ToppCellHippocampus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)|Hippocampus / BrainAtlas - Mouse McCarroll V32

CCL28 SOX30 APAF1 OBSCN

1.08e-0577794a799ccdb84014e978d9fbccf3d2fee8fbeac7b0c
ToppCellfacs-Diaphragm-Limb_Muscle-3m-Myeloid|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MSR1 CSF1R CFP ADGRG6 STAB1

1.13e-05165795518ee34c18065100a2f2c6e407d3a7866b908593
ToppCellE15.5-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MSR1 CSF1R GAS6 CFP STAB1

1.13e-051657958d3d5860a4785c4908160ae5fcb421ee80bd78ce
ToppCellfacs-Diaphragm-Limb_Muscle-3m-Myeloid-nan|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MSR1 CSF1R CFP ADGRG6 STAB1

1.13e-05165795becb8f726b84509ec29c75b530a3fe757651301d
ToppCellE15.5-Endothelial-lymphatic_endothelial_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MSR1 CSF1R GAS6 CFP STAB1

1.13e-0516579517ee6f269ed8d378465cf00ca59d48d8b106808e
ToppCellfacs-Diaphragm-Limb_Muscle-3m-Myeloid-macrophage|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MSR1 CSF1R CFP ADGRG6 STAB1

1.13e-05165795ae8dd9c00f96590f27ed21cd6314f4577e00e312
ToppCelldroplet-Kidney-nan-18m-Epithelial-Epcam____brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL16A1 CSF1R CCL28 LRP2 USH2A

1.20e-05167795ed7e785dcd25777f64e0c2596ada4f5a5ea17121
ToppCellfacs-Heart-RV-3m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MSR1 CSF1R SUSD1 CFP STAB1

1.23e-051687958ee57814c7e9d45444f48b6b269c4d535bc4d5e1
ToppCellfacs-Heart-RV-3m-Myeloid|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MSR1 CSF1R SUSD1 CFP STAB1

1.23e-05168795c1a5f4f4d32a1f8583048db709a7037cc9357ad8
ToppCellfacs-Heart-RV-3m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MSR1 CSF1R SUSD1 CFP STAB1

1.23e-05168795a405f0de70293f68b4e000c1fc8a9ad33d56539a
ToppCelldroplet-Spleen-nan-21m-Hematologic-proerythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MSR1 COL16A1 CSF1R LAMA1 ADGRE4P

1.31e-0517079503cb4e508356f85372a588c8d1c6babf2a012683
ToppCelldroplet-Spleen-nan-21m-Hematologic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MSR1 COL16A1 CSF1R LAMA1 ADGRE4P

1.34e-051717959498c35b2a2c3a339dc8c5d49c8ec20d8ad52753
ToppCelldroplet-Spleen-nan-21m-Hematologic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MSR1 COL16A1 CSF1R LAMA1 ADGRE4P

1.34e-05171795db544252f98e073e5bb4bec4a110cd58e6434435
ToppCellfacs-Heart-LA-3m-Myeloid|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MSR1 CSF1R SUSD1 CFP STAB1

1.46e-0517479530c083fe4711735e83dccfd00fcd746ae673d353
ToppCellfacs-Heart-LA-3m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MSR1 CSF1R SUSD1 CFP STAB1

1.46e-0517479546d19c1144fff19be682b7ba59d4c3e014f79e15
ToppCellfacs-Heart-LA-3m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MSR1 CSF1R SUSD1 CFP STAB1

1.46e-051747951802a52552256d1e25d8b328ba62dcfe41671900
ToppCellwk_20-22-Hematologic-Myeloid-CXCL9+_Mac|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

CSF1R RNF19B CFP ADGRE5 MIR9-1HG

1.50e-0517579548f5bdbfc1ba40c3fb6411f12a69e61da2138296
ToppCellPND10-Immune-Immune_Myeloid-Monocytic-Macrophage|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MSR1 CSF1R ADGRE4P CFP STAB1

1.50e-05175795a8b05972e1bec4de73feaa6c4a9bcbe6b50c8044
ToppCellnormal_Lung-Fibroblasts-Pericytes|normal_Lung / Location, Cell class and cell subclass

GAS6 OBSCN LTBP2 CDH19 ADGRG6

1.77e-05181795f74941e49950027360d71ea3b205fc20c6929766
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FRAS1 EGFR ZNRF3 RNF43 ADGRG6

2.01e-051867954e94158db52df41d71e67b02b9895a358eebee0f
ToppCellMonocytes-M2-like_CD16+_macrophages|Monocytes / Immune cells in Kidney/Urine in Lupus Nephritis

MSR1 GAS6 LTBP2 ADGRG6 STAB1

2.07e-0518779559e31c51183ed4c9a3d0792c8005ea3a12b28dfa
ToppCell10x5'-blood-Myeloid_Dendritic-DC2|blood / Manually curated celltypes from each tissue

TENM4 CSF1R GAS6 CFP ADGRG6

2.07e-05187795ab9c9930341527122f26fe5544c5c4818d1fd1b5
ToppCellCOVID-19-Heart-Fib_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

TENM4 EGFR PCSK6 LTBP2 CDH19

2.12e-05188795fe361215f4ba841aa5e1e581fb56f2f4d3ccd201
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-7|TCGA-Colorectal / Sample_Type by Project: Shred V9

LTBP2 F2RL2 PMS2CL RNF43 RUSC2

2.12e-0518879514bc73cf79c79c9f208369fd8d498e5b26e0114d
ToppCell5'-Adult-SmallIntestine-Hematopoietic-Myeloid-cDC2|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MSR1 TENM4 CSF1R CFP STAB1

2.34e-0519279590274b85f3d612b6a6d435860cd6d049ddeb1d96
ToppCellCOVID-19-Heart-Fib_2|Heart / Disease (COVID-19 only), tissue and cell type

TENM4 EGFR PCSK6 LTBP2 CDH19

2.46e-05194795d91c9f2ec47319051fc398320693fddbe8bbd4d6
ToppCell367C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

MSR1 CSF1R GAS6 ADGRG6 STAB1

2.52e-051957954008fa86b5166087a4b20f89ae07e1dfc87c855d
ToppCellCOVID-19-Heart-Fib_1|Heart / Disease (COVID-19 only), tissue and cell type

TENM4 EGFR PCSK6 LTBP2 CDH19

2.52e-05195795f423baa36ac7cdc383c033e35a7d17e6bf913323
ToppCell(3)_MNP-(3)_Macrophage_MARCOneg|(3)_MNP / Lung cell shreds - cell class (v4) and cell subclass (v4)

MSR1 CSF1R GAS6 ADGRG6 STAB1

2.52e-05195795e4b5e4b8832669fb4d1661ecd828b81e621d35c4
ToppCell343B-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

CSF1R GAS6 LTBP2 ADGRG6 STAB1

2.52e-0519579567b05a0cd2ca9924eca81a92cc6330eecb9d963c
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Myeloid-Monocytic-Nonclassical_Monocyte|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TMEM201 CSF1R SUSD1 CFP DNASE1L1

2.59e-0519679584c7f2153b5a9c4da7ae48fdf816a163c33d9a5e
ToppCellMS-mono1|MS / Condition, Cell_class and T cell subcluster

MSR1 CSF1R GAS6 ADGRG6 STAB1

2.65e-0519779532be48ee2a1397ed8f1ee8e60067dd9a96bece39
ToppCellMS-mono1-|MS / Condition, Cell_class and T cell subcluster

MSR1 CSF1R GAS6 ADGRG6 STAB1

2.65e-051977954b038a193ecc1df65bcb608091c513ddafd6c818
ToppCell3'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MSR1 CSF1R GAS6 CFP STAB1

2.65e-0519779567bf15ee83938bd40f6ecd5abaaf90ad95096d21
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL16A1 TENM4 WNT9A LTBP2 ADGRG6

2.65e-051977959d7a1c7dc70ba5e35645f19f9e056e4fa2494aa0
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL16A1 TENM4 WNT9A LTBP2 ADGRG6

2.65e-05197795090a251194da3e2806989d9a522588f83f52da7f
ToppCellCOVID-19_Severe-Myeloid-cDC|COVID-19_Severe / Disease group, lineage and cell class

CSF1R GAS6 APAF1 CFP ADGRG6

2.65e-05197795843b0f1cc26864ee635df7938c77552ee06fe00b
ToppCellwk_08-11-Epithelial-Distal_epithelial_progenitor-epi-tip_intermediate|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

FRAS1 ZNRF3 LAMA1 IRX6 RNF43

2.72e-0519879584697f316d9195ebe838cf57f4dbdd9feea43bec
ToppCellnormal_Lung-Myeloid_cells-mo-Mac|Myeloid_cells / Location, Cell class and cell subclass

CSF1R GAS6 LTBP2 ADGRG6 STAB1

2.72e-05198795fbd72ebaba73cc30e79dc8a8c3d46b6f863c1494
ToppCellMild-Myeloid-Macrophages-FCN1_high|Mild / Condition, Lineage, Cell class and cell subclass

CSF1R RNF19B GAS6 CFP STAB1

2.72e-0519879517aab4dc3b2cd6eb7dda77dd51bdc20490fcfe19
ToppCellwk_08-11-Epithelial-Distal_epithelial_progenitor|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

FRAS1 ZNRF3 LAMA1 IRX6 RNF43

2.72e-05198795eda85a592527992b51a00f288cff0c3239c47e6f
ToppCellCaecum-(6)_Macrophage-(61)_LYVE1_Macrophage|Caecum / shred on region, Cell_type, and subtype

MSR1 CSF1R CFP RUSC2 STAB1

2.72e-05198795e684c3934c163aef4d284b69435832d2c9614f2a
ToppCellCaecum-Macrophage-LYVE1_Macrophage|Caecum / Region, Cell class and subclass

MSR1 CSF1R CFP RUSC2 STAB1

2.72e-05198795a92c0cacb775aca6bbb302bd9e22c081a112a44d
ToppCellTransverse-Macrophage-LYVE1_Macrophage|Transverse / Region, Cell class and subclass

MSR1 CSF1R CFP ECE2 STAB1

2.78e-05199795facf79c256db5ae57bdb613e86ec90616a6f67ca
ToppCell5'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Glia_3_(BCAN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FRAS1 LAMA1 CDH19 MIR9-1HG ADGRG6

2.78e-05199795a76aa30fb264bdcbc0cb09113f814fc5a89e7319
ToppCellTransverse-(6)_Macrophage-(61)_LYVE1_Macrophage|Transverse / shred on region, Cell_type, and subtype

MSR1 CSF1R CFP ECE2 STAB1

2.78e-05199795dcc2a7f4d1fa30aaaad655dd59c5a2b039d264bf
ToppCellTracheal-10x5prime-Immune_Myeloid-Macrophage_other-Macro_interstitial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MSR1 CSF1R CFP ADGRE5 STAB1

2.78e-051997954b6d49b96bfcd6604b082bab620ae03276520885
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Serous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CCL28 ELAPOR1 RNF43 TECPR1 ADGRG6

2.85e-052007957c2d499af60654b7b28f172ac2c914ad49fb74b4
ToppCellBronchial-NucSeq-Immune_Myeloid-Monocytic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MSR1 CSF1R RAPGEF1 CFP STAB1

2.85e-052007958872d5fa101d413fb43b4231d476878678543035
ToppCellParenchymal-10x5prime-Stromal-Peri/Epineurial_-NAF_endoneurial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

COL16A1 EGFR OBSCN LTBP2 CDH19

2.85e-052007958a4c210a3130f7baedf15ecbc0f4903b97da0352
ToppCellPND01-03-samps-Mesenchymal-Pericyte-pericyte_E|PND01-03-samps / Age Group, Lineage, Cell class and subclass

SOX30 OBSCN LTBP2 OTOG

9.78e-0513579435928195cf34f055b353562c96f451aef2344d64
ToppCell356C-Fibroblasts-Fibroblast-E|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

FAM193B TMEM201 WDR83 ZMAT1

1.01e-04136794edfd453c9a650d69d05a5a3ab15f7df56349fa86
ToppCell356C-Fibroblasts-Fibroblast-E-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

FAM193B TMEM201 WDR83 ZMAT1

1.01e-0413679403e4e2353c23ceffde35b2d0aadd15299e3db09f
ToppCelldroplet-Pancreas-Exocrine-18m-Hematologic-leukocyte|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MSR1 CSF1R CFP STAB1

1.19e-04142794bf4a9633d128805a0d7e426d6fe6c29db1ff8c81
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_VISp_Col18a1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MPL F2RL2 DNAH14 ADGRG6

1.39e-04148794fc80c02b51cf55a04ce550838ee2f41d8f656f41
ToppCellfacs-Pancreas-Exocrine-3m-Hematologic-leukocyte|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MSR1 CSF1R CFP STAB1

1.39e-04148794bbf4933582b50b3412c805de5ed137107c996236
ToppCellfacs-Pancreas-Exocrine-3m-Hematologic-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MSR1 CSF1R CFP STAB1

1.39e-041487946543860e3207a7de92a35bb6004be51287582f7a
ToppCellfacs-Pancreas-Exocrine-3m-Hematologic|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MSR1 CSF1R CFP STAB1

1.39e-0414879479e376503a3f9504a1ec5af4a60a09cc80e19059
ToppCellPND01-03-samps-Myeloid-Granulocyte|PND01-03-samps / Age Group, Lineage, Cell class and subclass

MSR1 CSF1R ADGRE4P CFP

1.43e-041497947bdb396de8a1ef27ab0c2aaf1452576f4b0b5561
ToppCellPND01-03-samps-Myeloid-Granulocyte-neutrophil__Lgals3-negative|PND01-03-samps / Age Group, Lineage, Cell class and subclass

MSR1 CSF1R ADGRE4P CFP

1.43e-0414979450f53018e525b3d252caa8bed9e075b1bb1086dd
ToppCellfacs-Marrow-Granulocytes-24m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNRF3 F2RL2 RNF43 TECPR1

1.47e-04150794a3a4710820a244116a26204f40e7113a1e7236c5
ToppCellfacs-Marrow-Granulocytes-24m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNRF3 F2RL2 RNF43 TECPR1

1.47e-0415079413dcd519dacf08d5852aa3e029e0a3308de07321
ToppCelldroplet-Fat-Scat-21m-Myeloid-monocyte|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF1R ADGRE4P CFP F2RL2

1.47e-04150794b6e5e04aaf1c5265ac07581868d3159f9292a84c
ToppCellMyeloid-C_(Monocyte)|World / shred on cell class and cell subclass (v4)

MSR1 CSF1R ADGRE4P CFP

1.54e-041527949145dc014ed7f154c158d454dc2b9754396afcca
ToppCellfacs-Lung-Endomucin-24m-Myeloid-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MSR1 CSF1R ADGRE4P CFP

1.58e-041537949c3220604b7fa4d91577b6c46960960f49644ca1
ToppCellfacs-Lung-Endomucin-24m-Myeloid-Classical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MSR1 CSF1R ADGRE4P CFP

1.58e-04153794ba624782693b0daa642e50881dbf5f0663fea82d
ToppCellE18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MSR1 CSF1R CFP STAB1

1.62e-0415479479ebda35dd1719e157738d7c13e5b8ccc3991f03
ToppCellfacs-Heart-RV-24m-Myeloid|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MSR1 CSF1R SUSD1 CFP

1.62e-04154794709e7eedec11e675c6bbd55940f91dea5f715f4c
ToppCelldroplet-Mammary_Gland-nan-3m-Myeloid|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MSR1 CSF1R ADGRE4P CFP

1.62e-0415479412d3ecb0c4d814a91ac833fcb74db6b9dbc0a321
ToppCelldroplet-Mammary_Gland-nan-3m-Myeloid-macrophage|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MSR1 CSF1R ADGRE4P CFP

1.62e-0415479464192a0f78021551886bbaf929916392bce451c0
ToppCellfacs-Heart-RV-24m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MSR1 CSF1R SUSD1 CFP

1.62e-041547948c65d4ea787a75f20448b11beea571d7ec684721
ToppCelldroplet-Mammary_Gland-nan-3m-Myeloid-macrophage|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MSR1 CSF1R ADGRE4P CFP

1.62e-0415479493ace0a42f3ea94605b13acd79659602b3a31b74
ToppCellfacs-Heart-RV-24m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MSR1 CSF1R SUSD1 CFP

1.62e-0415479460e7c03d91ea87eb6226a744633cbe6efa9a9928
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MSR1 CSF1R CFP STAB1

1.67e-0415579493bfcf5c12cbb61a1e0444312afd2aa411a8bf50
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TEX15 VWCE ZNF705D ADGRG6

1.71e-04156794dd41ed918b07fa248da458a629b3c53cb7ea8764
ToppCellPND07-28-samps-Mesenchymal-Mesothelial|PND07-28-samps / Age Group, Lineage, Cell class and subclass

FRAS1 WNT9A LAMA1 LRP2

1.71e-04156794574f761962a7dd3308bd41fc529dd3ea1b8625f8
ToppCellPND07-28-samps-Mesenchymal-Mesothelial-Mesothelial|PND07-28-samps / Age Group, Lineage, Cell class and subclass

FRAS1 WNT9A LAMA1 LRP2

1.71e-04156794605d95a900e1443d3f6aae163ef2e893d3293203
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TEX15 VWCE ZNF705D ADGRG6

1.71e-04156794abf9dd075b1ca8f613c660cc82f8a5af071fb6ab
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TENM4 CCL28 ADGRE4P DNASE1L1

1.75e-04157794ec433d2fe827abdb647be4176c231b7052482b6f
ToppCellE12.5-Hematopoietic|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MSR1 CSF1R GAS6 STAB1

1.75e-04157794344351c7534440532c6cd4a95782ac90b10d45f3
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Myeloid-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MSR1 CSF1R LRP2 CFP

1.75e-04157794c8f516d3f5622202d3f8514f68614cd86ea3f667
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Myeloid|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MSR1 CSF1R LRP2 CFP

1.75e-041577944862a11ab8df27d26b4f1c1785e544a2d5b6db6e
ToppCell368C-Fibroblasts-Fibroblast-F|368C / Donor, Lineage, Cell class and subclass (all cells)

COL16A1 PCSK6 WNT9A MTBP

1.75e-0415779474038192f016f95f80e0189035ee8ccc22ceb1b8
ToppCellChildren_(3_yrs)-Epithelial-basal_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

FRAS1 IL17REL EGFR ELAPOR1

1.75e-041577946ee2692f705bdd93ba523dffaf2f0cd921b47e28
ToppCell368C-Fibroblasts-Fibroblast-F-|368C / Donor, Lineage, Cell class and subclass (all cells)

COL16A1 PCSK6 WNT9A MTBP

1.75e-04157794982e6ea78c7dabdb7c07c4a5fb2425d5e45b5b94
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Myeloid-macrophage|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MSR1 CSF1R LRP2 CFP

1.75e-04157794a0ec1628ce29841889f1d9d4ee9422921af7b0b5
DrugLobeline alpha (-) hydrochoride [134-63-4]; Up 200; 10.6uM; MCF7; HT_HG-U133A

EGFR PCSK6 RNF19B LTBP2 TEX15 F2RL2 MCOLN3

3.60e-061977476258_UP
Drug15(S)-15-methyl Prostaglandin E2; Down 200; 10uM; PC3; HT_HG-U133A

EGFR APAF1 PHTF2 BRINP1 RNF43 WDR59 RUSC2

3.85e-061997477494_DN
DrugMethazolamide [554-57-4]; Up 200; 17uM; MCF7; HT_HG-U133A

CSF1R EGFR GAS6 WDR59 RUSC2 STAB1

3.94e-051937463474_UP
DrugGanciclovir [82410-32-0]; Up 200; 15.6uM; MCF7; HT_HG-U133A

MSR1 EGFR SHFL PCSK6 LTBP2 MIR9-1HG

4.29e-051967463368_UP
DrugPivampicillin [33817-20-8]; Up 200; 8.6uM; MCF7; HT_HG-U133A

COL16A1 CSF1R RNF19B RAPGEF1 TEX15 WDR59

4.29e-051967463506_UP
DrugCGX 0596987; Up 200; 20uM; MCF7; HT_HG-U133A

COL16A1 TENM4 CSF1R ELAPOR1 MIR9-1HG STAB1

4.29e-051967466364_UP
DrugKynurenine, 3-hydroxy (R,S) [2147-61-7]; Up 200; 17.8uM; MCF7; HT_HG-U133A

PCSK6 GAS6 ADGRE5 WDR59 MIR9-1HG RUSC2

4.42e-051977462654_UP
DrugLymecycline [992-21-2]; Up 200; 6.6uM; MCF7; HT_HG-U133A

COL16A1 CSF1R PCSK6 SERGEF GAS6 ELAPOR1

4.42e-051977463514_UP
DrugBenfotiamine [22457-89-2]; Up 200; 8.6uM; HL60; HT_HG-U133A

FRAS1 SOX30 GAS6 F2RL2 MIR9-1HG ADGRG6

4.42e-051977462177_UP
Drug(-)-Cinchonidine [485-71-2]; Up 200; 13.6uM; MCF7; HT_HG-U133A

ZNF250 CSF1R SOX30 PHTF2 BRINP1 MIR9-1HG

4.54e-051987462772_UP
DrugAtropine sulfate monohydrate [5908-99-6]; Up 200; 5.8uM; PC3; HT_HG-U133A

CSF1R SERGEF BRINP1 F2RL2 WDR59 MIR9-1HG

4.54e-051987465865_UP
Drugnifedipine; Down 200; 10uM; MCF7; HG-U133A

TENM4 SHFL GAS6 ATG2B BRINP1 TEX15

4.67e-05199746603_DN
DrugCefmetazole sodium salt [56796-39-5]; Down 200; 8.2uM; MCF7; HT_HG-U133A

CSF1R EGFR PCSK6 GAS6 LTBP2 MIR9-1HG

4.67e-051997466086_DN
DrugKawain [500-64-1]; Up 200; 17.4uM; HL60; HT_HG-U133A

PCSK6 LRP2 CFP BRINP1 PCGF3 RNF43

4.67e-051997462337_UP
Diseasecomplement C1q tumor necrosis factor-related protein 5 measurement

MSR1 APAF1

3.36e-0411742EFO_0801494
DiseaseHematologic Neoplasms

MPL CSF1R

4.03e-0412742C0376545
DiseaseMyeloproliferative disease

MPL ATG2B

4.03e-0412742C0027022
Diseaselung non-small cell carcinoma (is_marker_for)

CSF1R EGFR SOX30 APAF1

8.75e-04169744DOID:3908 (is_marker_for)
DiseaseAdrenocortical carcinoma

EGFR ZNRF3

9.25e-0418742C0206686
DiseaseChronic myeloproliferative disorder

MPL PCNT

1.03e-0319742C1292778
Diseaseresponse to ziprasidone

ZP1 TENM4

1.14e-0320742GO_0097337
Diseasebody weight

COL16A1 SUSD1 WNT9A SYT14 BRINP1 LTBP2 CDH19 WDR59 DNAH14 ADGRG6

1.17e-0312617410EFO_0004338
DiseaseIntrahepatic Cholangiocarcinoma

EGFR RNF43

1.65e-0324742C0345905
DiseaseExtrahepatic Cholangiocarcinoma

EGFR RNF43

1.65e-0324742C3805278
DiseaseAdenocarcinoma of large intestine

EGFR ZNRF3 RNF43

1.83e-0396743C1319315
DiseaseL lactate dehydrogenase measurement

TENM4 STAB1

1.94e-0326742EFO_0004808
DiseaseCholangiocarcinoma

EGFR RNF43

1.94e-0326742C0206698
DiseasePancreatic Neoplasm

EGFR ZNRF3 RNF43

2.06e-03100743C0030297
DiseaseAcute Kidney Insufficiency

EGFR GAS6 LRP2

2.12e-03101743C1565662
DiseaseAcute kidney injury

EGFR GAS6 LRP2

2.12e-03101743C2609414
DiseaseKidney Failure, Acute

EGFR GAS6 LRP2

2.12e-03101743C0022660
DiseaseMalignant neoplasm of pancreas

EGFR ZNRF3 RNF43

2.18e-03102743C0346647
Diseaseattention deficit hyperactivity disorder (implicated_via_orthology)

ADGRE5 BRINP1

2.25e-0328742DOID:1094 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
CHSESTVSACESTAS

C2orf42

286

Q9NWW7
HNGCVRCSAFSVDST

APAF1

1126

O14727
RPSAHTSECFSTTAC

nan

11

P0DMU3
IASSCCTEVSHHISR

CCL28

26

Q9NRJ3
FLESQRSCVCHGSTT

BRINP1

406

O60477
AGRVASVHVDCSSAS

COL16A1

176

Q07092
GCVAHRDSDASETVC

ADGRG6

821

Q86SQ4
NSTHCTCEDGFRARS

ADGRE4P

26

Q86SQ3
DECSSGQHQCDSSTV

ADGRE5

211

P48960
STSHCGISTRCTERC

MIR9-1HG

66

Q13536
SDVVHIRTCSDSCAA

ATG2B

1341

Q96BY7
DATTVTECLHTFCRS

PCGF3

26

Q3KNV8
CCESTQRSVSDVASG

IRX6

26

P78412
SSCDTNLVLSHTGTC

FRAS1

876

Q86XX4
TSRCTCVTGGSHSSL

IL17REL

296

Q6ZVW7
VVVSSCSSHEEENRC

MCOLN3

6

Q8TDD5
VARLECSGAISAHCS

GLOD4

36

Q9HC38
IDRDSGTCHSCPTNT

ELAPOR1

611

Q6UXG2
SHSTCLTEACIRVAG

ECE2

136

P0DPD6
GTSCITNHTCSNADE

PCSK6

926

P29122
IIHTAGTSCTVSTDC

PGLYRP3

206

Q96LB9
THTCSSSEFQCASGR

LRP2

2861

P98164
CAGDATRTHICNTAV

CFP

296

P27918
TSRCESCGAVFHSEC

PLEKHM3

701

Q6ZWE6
HEGHVSDRCCVETSA

PCNT

616

O95613
TRACSHSEDAGVTCT

MSR1

436

P21757
DITTCHDVHNTCESS

F2RL2

241

O00254
ESCSFECVLSHESAS

OBSCN

2751

Q5VST9
VTDHGSCVRACGADS

EGFR

301

P00533
SSSEHLTCCEQGDIA

CSF1R

946

P07333
SSCLVGCAITQDHSD

HEATR5B

1026

Q9P2D3
ADGEDTTVRASTHCT

DNASE1L1

211

P49184
TSSSTHQRDGKFCDC

FAM193B

401

Q96PV7
SCHSGFELSSDGRTC

GAS6

181

Q14393
TSTACDRHTDVCSFS

DNAH14

2976

Q0VDD8
RGHCANSCERGDTTT

LTBP2

366

Q14767
HTSVCADCSAVFHRD

DEF8

466

Q6ZN54
SCIANSGSDCTSHLS

GEN1

706

Q17RS7
TESSSSDEFFCRCHR

GPR156

746

Q8NFN8
TSTNTLTIHVCDCGD

CDH19

561

Q9H159
LTIHVCDCGDSGSTQ

CDH19

566

Q9H159
SCVLSSAVHSQCVTG

WDR77

246

Q9BQA1
SITETHECFTACSQR

MTBP

846

Q96DY7
SADGVCHTSRCTTVL

OTOG

2706

Q6ZRI0
GDQHCRCSSTSSQSE

RUSC2

246

Q8N2Y8
SDSSVSLAAGVHCDR

RTN3

141

O95197
TLTACTLAGCTESSH

USH2A

2031

O75445
LHCAECHSSCTSETD

PHTF2

411

Q8N3S3
CLTGATEVSCGSEHN

SERGEF

331

Q9UGK8
CSESTSSCQSLEHGS

SYT14

401

Q8NB59
TSDECGSPRSHTAAC

RNF19B

681

Q6ZMZ0
CSLVGSTHHRCDVVT

LAMA1

1046

P25391
CHGSSSDSVVNCTDI

RNF43

471

Q68DV7
SSECTHSENSRSCEN

SOX30

676

O94993
HGSRCLRDSTHCVTT

SLURP2

36

P0DP57
DRRSTHTHSCSAADC

SHFL

196

Q9NUL5
GESHCATCSEDGSVR

WDR90

1446

Q96KV7
VRSCSHCSGQREAIS

nan

26

Q6ZSR3
ECSECGKTFSHRSTL

ZNF250

396

P15622
TSACHTSGLETCSTA

ZP1

531

P60852
ECRSSVTSDSEGAHV

PHTF1

391

Q9UMS5
SGQCSRNTSCETLDH

RAPGEF1

371

Q13905
HPTTDATSCTEIDCG

SUSD1

166

Q6UWL2
IAARECDRSHSGSSS

TECPR1

376

Q7Z6L1
TDIDECVTSSCEGHC

VWCE

141

Q96DN2
IDVACSNHGTCITGT

TENM4

631

Q6N022
GDGQRTCTCDTAHTV

STAB1

1561

Q9NY15
TCTCDTAHTVGDGLT

STAB1

1566

Q9NY15
TCVVDTTTRGCSEEA

TMEM201

616

Q5SNT2
AESGSCCTTHIANHS

MPL

611

P40238
SGEDCTHSSTIIQCL

ZNF705EP

121

A8MWA4
CCLSERDTHVVSCSE

WDR83

241

Q9BRX9
AADRSCTVSVHCSNH

WDR59

411

Q6PJI9
SGEDCTHSSTITQCL

ZNF705B

121

P0CI00
SGEDCTHSSTITQCL

ZNF705D

121

P0CH99
VETTCKCHGVSGSCT

WNT9A

211

O14904
CRDHTSDQLSTCREG

ZNF792

201

Q3KQV3
SSGQCHCSSSDSVVD

ZNRF3

556

Q9ULT6
HCSSSDSVVDCTEVS

ZNRF3

561

Q9ULT6
SIPDTGSHCSSECVA

PMS2CL

121

Q68D20
SSTGNDCDATCIGHT

TEX15

1246

Q9BXT5
SFDRCTGHSAEHTQC

UIMC1

216

Q96RL1
RTSTQEKSFECSHCG

ZNF426

216

Q9BUY5
CCSHTTAEASSLEHG

TXNRD3NB

36

Q6F5E7
VTRLECSGAISAHCS

ZMAT1

6

Q5H9K5