Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionstructural molecule activity

COL4A3 KRT4 KRT12 DMBT1 PLEC CCDC6 HMCN1

1.77e-03891407GO:0005198
GeneOntologyBiologicalProcesscerebellar Purkinje cell layer maturation

RERE ARCN1

3.67e-062402GO:0021691
GeneOntologyBiologicalProcesscerebellar cortex maturation

RERE ARCN1

1.10e-053402GO:0021699
GeneOntologyBiologicalProcessintermediate filament organization

DNAJB6 KRT4 KRT12 PLEC

1.33e-0575404GO:0045109
GeneOntologyBiologicalProcesscerebellum maturation

RERE ARCN1

2.19e-054402GO:0021590
GeneOntologyBiologicalProcessintermediate filament cytoskeleton organization

DNAJB6 KRT4 KRT12 PLEC

4.00e-0599404GO:0045104
GeneOntologyBiologicalProcessintermediate filament-based process

DNAJB6 KRT4 KRT12 PLEC

4.16e-05100404GO:0045103
GeneOntologyBiologicalProcesshindbrain maturation

RERE ARCN1

7.65e-057402GO:0021578
GeneOntologyBiologicalProcesscentral nervous system maturation

RERE ARCN1

1.31e-049402GO:0021626
GeneOntologyBiologicalProcessnegative regulation of inclusion body assembly

DNAJB6 DNAJB8

2.39e-0412402GO:0090084
DomainAA/rel_permease1

SLC7A11 SLC7A14

3.27e-0413392IPR002293
DomainAA_permease_2

SLC7A11 SLC7A14

3.27e-0413392PF13520
DomainSRCR

SSC4D DMBT1

8.70e-0421392PF00530
DomainAA-permease/SLC12A_dom

SLC7A11 SLC7A14

9.56e-0422392IPR004841
DomainAA_permease

SLC7A11 SLC7A14

9.56e-0422392PF00324
DomainSR

SSC4D DMBT1

1.24e-0325392SM00202
Domain-

SSC4D DMBT1

1.24e-03253923.10.250.10
DomainSRCR_1

SSC4D DMBT1

1.34e-0326392PS00420
DomainSRCR-like_dom

SSC4D DMBT1

1.34e-0326392IPR017448
DomainSRCR_2

SSC4D DMBT1

1.34e-0326392PS50287
DomainBromodomain_CS

PHIP BRWD1

1.34e-0326392IPR018359
DomainSRCR

SSC4D DMBT1

1.44e-0327392IPR001190
DomainDnaJ_domain_CS

DNAJB6 DNAJB8

1.44e-0327392IPR018253
DomainBROMODOMAIN_1

PHIP BRWD1

2.70e-0337392PS00633
DomainBromodomain

PHIP BRWD1

2.85e-0338392PF00439
DomainBROMODOMAIN_2

PHIP BRWD1

3.31e-0341392PS50014
DomainBROMO

PHIP BRWD1

3.47e-0342392SM00297
DomainBromodomain

PHIP BRWD1

3.47e-0342392IPR001487
Domain-

PHIP BRWD1

3.47e-03423921.20.920.10
DomainKeratin_I

KRT4 KRT12

3.80e-0344392IPR002957
DomainDnaJ

DNAJB6 DNAJB8

4.51e-0348392PF00226
DomainDnaJ

DNAJB6 DNAJB8

4.70e-0349392SM00271
DomainDNAJ_1

DNAJB6 DNAJB8

4.70e-0349392PS00636
DomainDNAJ_2

DNAJB6 DNAJB8

4.70e-0349392PS50076
Domain-

DNAJB6 DNAJB8

4.70e-03493921.10.287.110
DomainDnaJ_domain

DNAJB6 DNAJB8

5.08e-0351392IPR001623
DomainIntermediate_filament_CS

KRT4 KRT12

7.66e-0363392IPR018039
DomainIF

KRT4 KRT12

9.90e-0372392PS00226
DomainFilament

KRT4 KRT12

1.02e-0273392PF00038
DomainIGv

HMCN1 BTN2A3P

1.07e-0275392SM00406
DomainIF

KRT4 KRT12

1.10e-0276392IPR001664
Pubmed

Localization of basement membrane-associated protein isoforms during development of the ocular surface of mouse eye.

COL4A3 KRT4 KRT12

6.85e-07154139264260
Pubmed

The DNAJB6 and DNAJB8 protein chaperones prevent intracellular aggregation of polyglutamine peptides.

DNAJB6 DNAJB8

1.36e-06241223612975
Pubmed

Versatile members of the DNAJ family show Hsp70 dependent anti-aggregation activity on RING1 mutant parkin C289G.

DNAJB6 DNAJB8

4.06e-06341227713507
Pubmed

Expression of keratins K12, K4 and K14 during development of ocular surface epithelium.

KRT4 KRT12

4.06e-0634127531631
Pubmed

Using transgenic models to study the pathogenesis of keratin-based inherited skin diseases.

KRT4 KRT12

8.12e-06441210511477
Pubmed

Eyelid fusion and epithelial differentiation at the ocular surface during mouse embryonic development.

KRT4 KRT12

2.03e-05641215944823
Pubmed

A DNAJB chaperone subfamily with HDAC-dependent activities suppresses toxic protein aggregation.

DNAJB6 DNAJB8

2.03e-05641220159555
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

DNAJB6 RERE KAT6B PHIP IL21R PANK4 BRWD1 SCAPER

4.08e-05111641831753913
Pubmed

SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling.

DNAJB6 KRT4 TARDBP TAB2 KRT12 PLEC

4.63e-0555841627591049
Pubmed

Multiple roles of Pax6 in postnatal cornea development.

KRT4 KRT12

4.86e-05941236049534
Pubmed

A Spatiotemporal Requirement for Prickle 1-Mediated PCP Signaling in Eyelid Morphogenesis and Homeostasis.

KRT4 KRT12

4.86e-05941229450535
Pubmed

The homeodomain transcription factor PITX2 is required for specifying correct cell fates and establishing angiogenic privilege in the developing cornea.

KRT4 KRT12

7.41e-051141225044936
Pubmed

Card9 protects fungal peritonitis through regulating Malt1-mediated activation of autophagy in macrophage.

TARDBP PLEC

8.88e-051241235850054
Pubmed

The canonical Wnt signaling antagonist DKK2 is an essential effector of PITX2 function during normal eye development.

KRT4 KRT12

8.88e-051241218367164
Pubmed

P62/SQSTM1 is a novel leucine-rich repeat kinase 2 (LRRK2) substrate that enhances neuronal toxicity.

DNAJB6 DNAJB8

8.88e-051241229519959
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ATMIN ARFGEF3 RERE TRO MADD

1.13e-0440741512693553
Pubmed

Aberrant expression of a beta-catenin gain-of-function mutant induces hyperplastic transformation in the mouse cornea.

KRT4 KRT12

1.61e-041641220332116
Pubmed

Limb-Girdle Muscular Dystrophy Overview – RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY

DNAJB6 PLEC

2.81e-042141220301582
Pubmed

Mammalian HSP40/DNAJ homologs: cloning of novel cDNAs and a proposal for their classification and nomenclature.

DNAJB6 DNAJB8

3.09e-042241211147971
Pubmed

The diverse members of the mammalian HSP70 machine show distinct chaperone-like activities.

DNAJB6 DNAJB8

3.38e-042341221231916
Pubmed

New genetic associations detected in a host response study to hepatitis B vaccine.

COL4A3 SSC4D TMEM121B TRO IL21R MADD

3.85e-0482441620237496
Pubmed

Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.

DNAJB6 TRO ARCN1

4.27e-0412441323000965
Pubmed

A protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway.

TAB2 PLEC SLC7A11 TRO

4.38e-0430241430561431
Pubmed

Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.

TARDBP PLEC TRO ARCN1 BRWD1 SCAPER

4.45e-0484741635235311
Pubmed

Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives.

TARDBP PHIP ARCN1 BRWD1

4.60e-0430641418973680
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

DNAJB6 ARFGEF3 TAB2 PLEC CCDC6 MADD

4.86e-0486141636931259
Pubmed

Identification and characterization of a set of conserved and new regulators of cytoskeletal organization, cell morphology and migration.

PHIP BRWD1

5.39e-042941221834987
Pubmed

Peptidylprolyl isomerase A governs TARDBP function and assembly in heterogeneous nuclear ribonucleoprotein complexes.

TARDBP ZNF875

5.78e-043041225678563
Pubmed

Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery.

PHIP BRWD1

6.58e-043241216964240
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

DNAJB6 TARDBP PLEC CCDC6 ARHGAP40 ARCN1

6.72e-0491641632203420
Pubmed

Fine mapping and association studies of a high-density lipoprotein cholesterol linkage region on chromosome 16 in French-Canadian subjects.

ATMIN LDHD

7.87e-043541219844255
Pubmed

Systematic and quantitative assessment of the ubiquitin-modified proteome.

DNAJB6 TRO ARCN1

8.64e-0415841321906983
Pubmed

A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.

DNAJB6 TRO ARCN1

9.29e-0416241321890473
Pubmed

∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.

DNAJB6 TARDBP PLEC GPRC5A ARCN1

9.45e-0464741526618866
Pubmed

Novel Cul3 binding proteins function to remodel E3 ligase complexes.

PHIP BRWD1

1.03e-034041225011449
Pubmed

ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.

DNAJB6 NFYC KRT12 PLEC GPRC5A

1.03e-0366041532780723
Pubmed

A neurogenomics approach to gene expression analysis in the developing brain.

TAB2 MADD SCAPER

1.07e-0317041315582152
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

COL4A3 DMBT1 HMCN1

1.16e-0317541328071719
Cytoband17q12

KRT12 GGNBP2

3.57e-039941217q12
GeneFamilyWD repeat domain containing|DDB1 and CUL4 associated factors

PHIP BRWD1

4.01e-0418302498
GeneFamilyDNAJ (HSP40) heat shock proteins|C2 tensin-type domain containing

DNAJB6 DNAJB8

2.98e-0349302584
ToppCellClub-club-16|World / Class top

KRT4 GPRC5A ARHGAP40 HMCN1

1.59e-05165414684f3c4872bd630d3f744f15d57dccfd34e96160
ToppCellControl|World / group, cell type (main and fine annotations)

COL4A3 ARFGEF3 DMBT1 GPRC5A

1.71e-05168414a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ARFGEF3 KRT4 GPRC5A ARHGAP40

2.33e-05182414215c303df42f13597b2c7a95cb157c6bc7aca9a1
ToppCellEnterocyte_Progenitors-C_06|Enterocyte_Progenitors / shred on cell type and cluster

DMBT1 PLEC GPRC5A ARHGAP40

2.88e-05192414b9938e1a929c00628cc6ebfdf10cf285167f445c
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT12 TMEM121B TRO MADD

2.94e-05193414be28070c049e7cb68bcd54f582226eb2f5e4bc1c
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT12 TMEM121B TRO MADD

2.94e-051934140c652ebe22ce5d2927599dd97ef1920547858395
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT12 TMEM121B TRO MADD

2.94e-051934148689a70a33a7c3823dc647d41ac0160e7c3ae396
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_airway_secretory-Secretory_Club|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ARFGEF3 KRT4 GPRC5A ARHGAP40

3.06e-05195414b9e8f405f6d837bb39b615836d3e2df349737c0e
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RERE SLC7A14 MADD SCAPER

3.06e-051954143e519cffa6144a62b06124642a14c9ff39b76554
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RERE SLC7A14 MADD SCAPER

3.06e-051954147796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell356C-Epithelial_cells-Epithelial-I_(AT1)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

COL4A3 GPR161 KRT4 GPRC5A

3.18e-0519741469d5b8588046d119b5dff9a7fd6f49e97e00a5b7
ToppCell356C-Epithelial_cells-Epithelial-I_(AT1)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

COL4A3 GPR161 KRT4 GPRC5A

3.18e-05197414e6cbfa267eb2e05b441fd034786faae07bb0e081
ToppCelldistal-2-Epithelial-Club|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ARFGEF3 KRT4 GPRC5A ARHGAP40

3.24e-051984143055c03896fbfac82a3072e51c0c54d68131cf1a
ToppCelldistal-Epithelial-Club-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ARFGEF3 KRT4 GPRC5A ARHGAP40

3.24e-05198414e56a5ffadfa4d1e34d34aec43eaf560cd80286e1
ToppCellBiopsy_Control_(H.)-Epithelial-SCGB3A2+_SCGB1A1+|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

ARFGEF3 KRT4 GPRC5A ARHGAP40

3.24e-05198414a3d4b6e4259ded2193d94d2ff6d48cf67214fc35
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_secretory-Secretory_Club|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ARFGEF3 KRT4 GPRC5A ARHGAP40

3.24e-051984145d57acbe0d245f8bd217eeea07af060092898fbd
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_airway_secretory|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ARFGEF3 KRT4 GPRC5A ARHGAP40

3.31e-05199414a8bfc0b93ad9968cf52a25be86995ffe436bd636
ToppCellBronchial-10x5prime-Epithelial-Epi_alveolar|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A3 ARFGEF3 DMBT1 GPRC5A

3.31e-05199414a38a981cffa61c8444a980916de7414e689a1b63
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_secretory|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ARFGEF3 KRT4 GPRC5A ARHGAP40

3.31e-0519941470c0b9cff195d3d24e98443a729e211cac20c90f
ToppCell(7)_Epithelial_cells-(7)_Epithelial-I_(AT1)|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

COL4A3 GPR161 KRT4 GPRC5A

3.31e-051994145a002d49a8b84c158f7b4d7a3e78e6a937757bb7
ToppCelldistal-3-Epithelial-Club|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ARFGEF3 KRT4 GPRC5A ARHGAP40

3.31e-051994141a0c3506df2438f5be40a8ea72effe5f8ebd35c4
ToppCellStriatum-Endothelial-ENDOTHELIAL_TIP-Dcn_1|Striatum / BrainAtlas - Mouse McCarroll V32

GPRC5A ARHGAP40 SLC7A11

1.38e-04109413f4b9fe5335cabe48a5fae7ec51bab0d7bdb17321
ToppCellStriatum-Endothelial-ENDOTHELIAL_TIP|Striatum / BrainAtlas - Mouse McCarroll V32

GPRC5A ARHGAP40 SLC7A11

1.38e-04109413a84a4a3ac19692e5595b9820d49e12ae336f4bbf
ToppCellStriatum-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn_(Dcn)-|Striatum / BrainAtlas - Mouse McCarroll V32

GPRC5A ARHGAP40 SLC7A11

1.38e-04109413f7d7b67f7585f2ae0ac905bcf3980264cf9234b8
ToppCellStriatum-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1|Striatum / BrainAtlas - Mouse McCarroll V32

GPRC5A ARHGAP40 SLC7A11

1.38e-04109413f007fa3dc92d6c8543585e47ccec218263b3266e
ToppCellStriatum-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn_(Dcn)|Striatum / BrainAtlas - Mouse McCarroll V32

GPRC5A ARHGAP40 SLC7A11

1.38e-041094138460683529759585bd363d10a16ee13af2bd4e28
ToppCellControl-Endothelial-Epi-like-Alv_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DACT2 SLC7A14 ARCN1

4.03e-041574132c369660c752c0fb3bd798a561d3359e2f9aa983
ToppCellControl-Endothelial-Epi-like|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DACT2 SLC7A14 ARCN1

4.03e-041574134d02c50d5d1b892ea241e98724386d8a5a156a46
ToppCellfacs-Heart-LV-24m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT12 DNAJB8 LLCFC1

4.11e-0415841312a82230c01de552f12977634c304626e1cd6903
ToppCellfacs-Thymus-Thymus_Flowthrough-18m-Epithelial|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DACT2 DMBT1 TMEM121B

4.11e-0415841312661763d1c309106801cb710c04cd2b62d16cba
ToppCellfacs-Thymus-Thymus_Flowthrough-18m-Epithelial-TECs|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DACT2 DMBT1 TMEM121B

4.11e-041584130792c39e6fc0745095af7812de2d50949540d60f
ToppCellfacs-Heart-LV-24m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT12 DNAJB8 LLCFC1

4.11e-04158413bd432ecd2524656804e7c2775250e27db7906b70
ToppCellfacs-Thymus-Thymus_Flowthrough-18m-Epithelial-epithelial_cell_of_thymus|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DACT2 DMBT1 TMEM121B

4.11e-04158413e7db50d6dfaf7280a73a0d5b5aa4f43ea2762d72
ToppCellClub_cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

ARFGEF3 KRT4 GPRC5A

4.18e-04159413a7bcff268b1962a561fd2848e01ae16565bce895
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligodendroglioma|TCGA-Brain / Sample_Type by Project: Shred V9

ARFGEF3 SLC7A14 MADD

4.34e-041614135f6b2d7f80a8ee16651e304481d2da3fae313824
ToppCellFetal_29-31_weeks-Epithelial-club_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ARFGEF3 GPRC5A ARHGAP40

4.42e-041624135c9bc3c3857a99d8a3caf359a7eb279ce9cc1c81
ToppCell343B-Epithelial_cells-Epithelial-A_(AT2)-|343B / Donor, Lineage, Cell class and subclass (all cells)

ARFGEF3 DMBT1 GPRC5A

4.58e-04164413beaa13a75c3bb72446c85084d75e9fe3f15fd3d4
ToppCell343B-Epithelial_cells-Epithelial-A_(AT2)|343B / Donor, Lineage, Cell class and subclass (all cells)

ARFGEF3 DMBT1 GPRC5A

4.58e-04164413d005cfd821b87548b075120bffe65a0be9860463
ToppCelldroplet-Bladder-BLADDER-1m-Epithelial-basal_bladder_epithelial_cell_(Krt5+)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT12 CCDC6 SLC7A11

4.66e-04165413936581de8fcd097401707438b9bbe89dd4e3e247
ToppCellwk_15-18-Epithelial-Airway_epithelial_progenitor-epi-prox-progenitor_intermediate_|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ARFGEF3 GPRC5A SLC7A11

4.66e-04165413f6887c64af0f26e33316bc5587487e24d76ece2a
ToppCellfacs-Lung-nan-3m-Epithelial-type_I_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A3 ARFGEF3 GPRC5A

4.74e-0416641311b0ae82b3068ef91715dbdd49fe8e9791b4a480
ToppCellfacs-Lung-nan-3m-Epithelial-Alveolar_Epithelial_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A3 ARFGEF3 GPRC5A

4.74e-04166413fcc1aec31ebd39432d4cb284dc8fadf34e3c566a
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_IT|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

DACT2 KRT12 TMEM121B

4.83e-04167413f1ce6e64ebede1f3ef36fe982f46919fd1f814dd
ToppCellfacs-Lung-24m-Epithelial-airway_epithelial-club_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KRT12 ARHGAP40 SLC7A11

5.17e-04171413bd339e482f09a3fa04b086029b94f45205b8a6c5
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2-Transitional_Club-AT2_L.0.4.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ARFGEF3 GPRC5A ARHGAP40

5.17e-04171413d5960b40ad5b87aaa00c93a6b31cdf41cc4f1375
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ARFGEF3 GPRC5A ARHGAP40

5.17e-04171413fd59ac4a39748840b2ee1c930ea475433ff61485
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-epithelial_cell_of_lung|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ARFGEF3 GPRC5A ARHGAP40

5.17e-04171413d382430e5cdd0f2aac4fc093d8fe8d66efb4629b
ToppCellfacs-Trachea-nan-24m-Epithelial-basal_epithelial_cell_of_tracheobronchial_tree|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT4 DMBT1 ARHGAP40

5.17e-04171413d2a10e94b0490120d1420b944302eb841f902c64
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ARFGEF3 GPRC5A ARHGAP40

5.17e-041714134347e6f62c04ea43299893ad4b79719049009a56
ToppCellfacs-Lung-24m-Epithelial-airway_epithelial-club_cell-club_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KRT12 ARHGAP40 SLC7A11

5.17e-041714138ed98f223143bd81d9819e9a420eb9cc81ee6c53
ToppCellfacs-Heart-LV-3m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LDHD PTX4 HMCN1

5.26e-04172413f2c17c49b375b28ad47dc6cabda62f1c238023dd
ToppCellfacs-Heart-LV-3m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LDHD PTX4 HMCN1

5.26e-041724136ab4f01098dddb789df298ddf97b3c384405ee6c
ToppCellwk_15-18-Epithelial-Distal_epithelial-type_I_pneumocyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

COL4A3 KRT4 GPRC5A

5.44e-041744132cd6638b361ca05ab83d09ce657194aed97873b7
ToppCellAT1_cells-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

COL4A3 CSRNP1 GPRC5A

5.62e-041764134a30bb771297b30926fb98e2b5ec0dbdc46feac7
ToppCellwk_15-18-Epithelial-Proximal_epithelial-Proximal_secretory_3|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ARFGEF3 KRT4 GPRC5A

5.62e-041764138d9d0fb46c418b2067be58aec822e8c2b1561461
ToppCellClub_cells-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

KRT4 GPRC5A HMCN1

5.62e-0417641388c4ed0ab4a4ede8cad21385d799b723b5786cd9
ToppCellFetal_29-31_weeks-Epithelial-club_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ARFGEF3 GPRC5A ARHGAP40

5.62e-041764133bbac5c2397535631fce8fa98f6ddb4fe0260351
ToppCellAT1_cells-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

COL4A3 KRT4 GPRC5A

5.72e-041774133128b8d04687acee1ac4190b2569d6328b98eaf3
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 SSC4D HMCN1

5.72e-04177413c9e8149639551a4c8daa90fcb2b895fdcff2e2ba
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ARFGEF3 GPRC5A ARHGAP40

5.81e-04178413f5ed4a6e3eb8056b1be1fb311021710c95bdf888
ToppCellPND28-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DACT2 COL4A3 GPRC5A

5.81e-04178413a3af5d9c55858e36be0498081029ecb0acaeb3d3
ToppCellPND28-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DACT2 COL4A3 GPRC5A

5.81e-04178413b3b88989bd602cfb55bb5c47731deb99288a8952
ToppCell15-Trachea-Epithelial-Goblet-like_secretory|Trachea / Age, Tissue, Lineage and Cell class

ARFGEF3 GPRC5A ARHGAP40

5.81e-04178413f0557920b9b3e7c4f39938d1b524aa58711af4d2
ToppCellAT1_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

COL4A3 KRT4 GPRC5A

5.91e-041794131603117b52623663458a977c94bf7f9f6c1114b8
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 SSC4D ARHGAP40

5.91e-0417941355bc69f107fc710db7617c428575792adfdbbcc1
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 SSC4D HMCN1

5.91e-04179413666072c0e8448dbaec1683d18368ec2502453f90
ToppCellControl-Epithelial-Goblet|Control / Disease state, Lineage and Cell class

ARFGEF3 KRT4 GPRC5A

6.00e-041804135293d23b8b8ea587239ffde561b70bad01632521
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

ARFGEF3 GPRC5A ARHGAP40

6.00e-04180413b509c7d6bdfba672065fb722874bdc68de72ba1c
ToppCellAT1_cells-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

COL4A3 KRT4 GPRC5A

6.00e-04180413ff4728782c3ec814ba071cc22b7894abdd9da837
ToppCellLPS_only-Epithelial_alveolar-AT_2-AT2_Progenitor|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DACT2 ARFGEF3 GPRC5A

6.10e-041814130513b9e6673ff7bf8e72ba123ca3794b65d10170
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-Tuft-related|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LDHD DMBT1 SLC7A11

6.10e-041814131d3d1b5a6efe9cedd03b7e0b5684df97f0246729
ToppCellfacs-Heart-RA-24m-Myeloid-macrophage|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT4 GPRC5A ARHGAP40

6.10e-04181413c68d272eb41f81bd8ea4d0360733a2396bc87037
ToppCellAT1-AT2_cells-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

COL4A3 KRT4 GPRC5A

6.10e-04181413ca23ce4f2c7b684d8ddd0e8619b3b696023d75e3
ToppCellfacs-Heart-RA-24m-Myeloid-macrophage|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT4 GPRC5A ARHGAP40

6.10e-041814135e5eb89f224ee48065a328ade030cbc4dcdcac12
ToppCell390C-Lymphocytic-CD4_T-cell-Treg_cell_2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

GPRC5A CCDC6 MADD

6.10e-041814139275531e896e118cee043ed94fd31a0070d9581c
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-Tuft-related-BEST4+_epithelial|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LDHD DMBT1 SLC7A11

6.10e-041814130069e8308de932df43660bbe926637c57b8bf7f6
ToppCellControl-Epithelial_cells-Airway_club|Control / group, cell type (main and fine annotations)

ARFGEF3 GPRC5A ARHGAP40

6.10e-04181413c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCellControl-Epithelial_alveolar-AT_1-AT1-AT2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DACT2 COL4A3 GPRC5A

6.20e-04182413a95956ce4adccb34cc0c47ebfa1878ce4617904e
ToppCell390C-Lymphocytic-CD4_T-cell-Treg_cell_2|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

GPRC5A CCDC6 MADD

6.20e-0418241321744c9c792e57d5d41b25986f419b2358c7057b
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

ARFGEF3 KRT4 ARHGAP40

6.20e-041824133f1a666fe27dd7529c114539ed5f6b8ca585c875
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-AT1-AT2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DACT2 COL4A3 GPRC5A

6.30e-0418341306ac66726ec53db810ebb90ec69cfdb903da53f6
ToppCellCOPD-Epithelial-ATII|World / Disease state, Lineage and Cell class

ARFGEF3 DMBT1 GPRC5A

6.30e-041834138e9aab4eeec2e282c2cab9bfca6dbf40d660c7b9
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-AT2_Progenitor|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DACT2 COL4A3 GPRC5A

6.40e-041844137cc5796557379c3d1db078c1aeda40659c6e401c
ToppCellControl-Epithelial-Goblet|World / Disease state, Lineage and Cell class

ARFGEF3 KRT4 GPRC5A

6.50e-041854139a793e6016295a63820e9d7563f195494ac692e7
ToppCell367C-Endothelial_cells-Endothelial-B_(Artery)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CSRNP1 GPRC5A SLC7A11

6.50e-04185413b57dae20c21f984edd2acee4344d86f033108ebf
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Children_(3_yrs) / Lineage, Cell type, age group and donor

ARFGEF3 GPRC5A ARHGAP40

6.50e-0418541398b8ee42b89d97e4c9db01740e0c193503c68f2c
ToppCell367C-Endothelial_cells-Endothelial-B_(Artery)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CSRNP1 GPRC5A SLC7A11

6.50e-04185413d3b054d203e575c1bb5455aa7a2e551a0957a760
ToppCelldroplet-Thymus-nan-3m-Lymphocytic-nan|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMCN1 SLC7A11 IL21R

6.50e-04185413aa2c36e2cce0f0a536cd1dfc3788b6fee6f21b6b
ToppCellIPF-Epithelial-ATII|IPF / Disease state, Lineage and Cell class

ARFGEF3 DMBT1 GPRC5A

6.50e-04185413563b4e6d92bb5d77a3829556116a8e99aebac615
ToppCell3'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DACT2 ARFGEF3 SLC7A14

6.50e-04185413eb78614c4acf8d2ce7874d7e51e16997b76127ef
ToppCellIPF-Epithelial-ATII|World / Disease state, Lineage and Cell class

ARFGEF3 DMBT1 GPRC5A

6.60e-041864136a4ff2da0af0f5e590d9f9daa5b5e9ac8c868947
ToppCellCOPD-Epithelial-Goblet|World / Disease state, Lineage and Cell class

ARFGEF3 KRT4 GPRC5A

6.60e-04186413d75fe7640a4b2c450c9759a1b3c3ef2a087f0092
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ARFGEF3 DMBT1 SLC7A11

6.60e-04186413acfa68a2afb7d2b51c9b469a1965fe5cc5d5e64e
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT12 TMEM121B MADD

6.60e-041864137278a1a1bf9bb27aeb03852134defb31b62f30d6
ToppCellControl-Epithelial-ATII|World / Disease state, Lineage and Cell class

ARFGEF3 DMBT1 GPRC5A

6.60e-04186413f4b6e401e19a71beddc73d8a1e08359f7c4025cf
ToppCell367C-Epithelial_cells-Epithelial-E_(AT2)-|367C / Donor, Lineage, Cell class and subclass (all cells)

COL4A3 DMBT1 GPRC5A

6.71e-0418741311670a85db87cbb3e78022a589632173604b0940
ToppCellLPS-antiTNF-Epithelial_alveolar|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DACT2 COL4A3 GPRC5A

6.71e-04187413201ff693e4756ee3e44762885b3a303a77eb535b
ToppCell367C-Epithelial_cells-Epithelial-E_(AT2)|367C / Donor, Lineage, Cell class and subclass (all cells)

COL4A3 DMBT1 GPRC5A

6.71e-041874130277d4e54bd4d48f30241c2951a569209423fee8
ToppCellEpithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|World / Lineage, Cell type, age group and donor

ARFGEF3 GPRC5A ARHGAP40

6.71e-0418741381cc8435b2704a9a8287b3f54acaae0f11dd4ac7
ToppCellfacs-Bladder|facs / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT4 GPRC5A SLC7A11

6.71e-04187413dd5ca59417fd1b388fd975f0f3e1f3245d66ebc5
Diseasemeningitis

RERE SCAPER

9.78e-0511402MONDO_0021108
DiseaseTourette syndrome, schizophrenia

GGNBP2 RERE

2.70e-0418402EFO_0004895, MONDO_0005090
DiseaseLimb-girdle muscular dystrophy

DNAJB6 PLEC

5.70e-0426402cv:C0686353
DiseaseMuscular Dystrophies, Limb-Girdle

DNAJB6 PLEC

8.66e-0432402C0686353
DiseaseHuntington's disease (implicated_via_orthology)

DNAJB6 DNAJB8

8.66e-0432402DOID:12858 (implicated_via_orthology)
Diseasebehavior

DNAJB6 LDHD

2.54e-0355402GO_0007610

Protein segments in the cluster

PeptideGeneStartEntry
CGFSSSFGCNYGMES

BTN2A3P

556

Q96KV6
FSFIMFTSAGSEGTG

COL4A3

1581

Q01955
AAMQSSCSSTSGGGG

CCDC6

21

Q16204
EAFSSFNMLGCSGGS

DNAJB8

146

Q8NHS0
FNMLGCSGGSHTTFS

DNAJB8

151

Q8NHS0
TFLMSSFTFCGSFTG

GPRC5A

191

Q8NFJ5
YDSTMGGSICGNGSS

KAT6B

1686

Q8WYB5
SNTSTEGFGGIMSFA

MADD

836

Q8WXG6
ASCGGGFSAASMFGS

KRT12

51

Q99456
GFSAASMFGSSSGFG

KRT12

56

Q99456
CNGSDCGYSSSMEGS

GGNBP2

461

Q9H3C7
GDASSCFLESLMGFS

CSRNP1

546

Q96S65
SSVSMSGGAGRCSSG

KRT4

31

P19013
CTFSGFSLSTSGMCV

IGHV2-70

41

P01814
MSTEGGFGGTSSSDA

NFYC

1

Q13952
CMVSSEGGSSAASVF

HMCN1

591

Q96RW7
MAECGASGSGSSGDS

PANK4

1

Q9NVE7
GLTSFSSTSFGGSGM

DNAJB6

171

O75190
SSTSFGGSGMGNFKS

DNAJB6

176

O75190
TDAFMDTCFQSGGVS

ATMIN

476

O43313
SGFYEMSDGGSCSLS

DACT2

126

Q5SW24
ASDFRGGSLMSGSSA

ARFGEF3

1096

Q5TH69
DASLCGMAATGASGT

LDHD

161

Q86WU2
SFSVGGMFLATGSTD

BRWD1

331

Q9NSI6
GDTGFSCSQDSGTDM

GPR161

391

Q8N6U8
SFCFSLASVMVFSGG

LLCFC1

91

Q96L11
DMDTFDSGFVGSDCS

IL21R

486

Q9HBE5
CDGARGSFTSSSNFM

DMBT1

2081

Q9UGM3
DFSASMGSGSVSFCG

SCAPER

471

Q9BY12
FGSSAVSGGSTAAMI

ARCN1

186

P48444
YTMGGDFSGTAQDCS

KIF2B

311

Q8N4N8
GGGFDSSEAFVGSMS

PTX4

411

Q96A99
PTSSCSMTAADFGGG

TMEM121B

126

Q9BXQ6
GFNVFGMSSSSGASN

TAB2

136

Q9NYJ8
GFNGGFGSSMDSKSS

TARDBP

396

Q13148
SMAAFAGMCDGGSTE

RERE

336

Q9P2R6
GTAAGASALSSMFDS

SLC7A14

146

Q8TBB6
SCFGSMNGGVFAVSR

SLC7A11

326

Q9UPY5
GSAGCSTGVESSSMD

ARHGAP40

16

Q5TG30
CSSFSAGGMFLATGS

PHIP

326

Q8WWQ0
STGFGGAMSTSADFG

TRO

986

Q12816
GAMSTSADFGGTLST

TRO

991

Q12816
GCGAAMAATTNAFFG

SSC4D

231

Q8WTU2
GSFDATGSGFSMTFS

PLEC

4641

Q15149
MSCSGAGGITAFVAF

ZNF875

21

P10072