Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainSynaptotagmin

SYT3 SYT6 SYT7 SYT5

3.11e-0620974IPR001565
Pubmed

Synaptotagmins 3 and 7 mediate the majority of asynchronous release from synapses in the cerebellum and hippocampus.

SYT3 SYT6 SYT7 SYT5

3.34e-105101439116209
Pubmed

Conserved N-terminal cysteine motif is essential for homo- and heterodimer formation of synaptotagmins III, V, VI, and X.

SYT3 SYT6 SYT7 SYT5

8.35e-099101410531343
Pubmed

Synaptotagmin-3 drives AMPA receptor endocytosis, depression of synapse strength, and forgetting.

SYT3 SYT6 SYT5

9.49e-084101330545844
Pubmed

Identification of synaptotagmin effectors via acute inhibition of secretion from cracked PC12 cells.

SYT6 SYT7 SYT5

4.72e-076101312860971
Pubmed

Phospholipid composition dependence of Ca2+-dependent phospholipid binding to the C2A domain of synaptotagmin IV.

SYT3 SYT6 SYT5

4.72e-07610138626542
Pubmed

Distinct developmental expression of synaptotagmin I and IX in the mouse brain.

SYT3 SYT6 SYT5

1.97e-069101316407767
Pubmed

SYNCRIP, a cytoplasmic counterpart of heterogeneous nuclear ribonucleoprotein R, interacts with ubiquitous synaptotagmin isoforms.

SYT3 SYT7 SYT5

3.86e-0611101310734137
Pubmed

Alternative splicing of synaptotagmins involving transmembrane exon skipping.

SYT7 SYT5

8.35e-062101210556508
Pubmed

Regionally specific expression of L1 and sialylated NCAM in the retinofugal pathway of mouse embryos.

L1CAM NCAM1

8.35e-062101215022265
Pubmed

Lymph node mapping in patients with bladder cancer undergoing radical cystectomy and lymph node dissection to the level of the inferior mesenteric artery.

SYT3 SYT6

8.35e-062101220002670
Pubmed

Expression of NCAM isoforms during skeletal myogenesis in the mouse embryo.

NCAM1 CHRNA1

8.35e-06210121421527
Pubmed

Effect of Cell Adhesion Molecules on the Neurite Outgrowth of Induced Pluripotent Stem Cell-Derived Dopaminergic Neurons.

L1CAM NCAM1

8.35e-062101226990843
Pubmed

STAT5BN642H drives transformation of NKT cells: a novel mouse model for CD56+ T-LGL leukemia.

NCAM1 STAT5B

8.35e-062101230967617
Pubmed

L1-CAM and N-CAM: From Adhesion Proteins to Pharmacological Targets.

L1CAM NCAM1

8.35e-062101226478212
Pubmed

Neural cell adhesion molecule, NCAM, regulates thalamocortical axon pathfinding and the organization of the cortical somatosensory representation in mouse.

L1CAM NCAM1

8.35e-062101222723769
Pubmed

Developmental expression of neural cell adhesion molecules in the mouse neocortex and olfactory bulb.

L1CAM NCAM1

8.35e-06210121723996
Pubmed

The fourth immunoglobulin-like domain of NCAM contains a carbohydrate recognition domain for oligomannosidic glycans implicated in association with L1 and neurite outgrowth.

L1CAM NCAM1

8.35e-06210128509458
Pubmed

Cell adhesion molecules in the early developing mouse retina: retinal neurons show preferential outgrowth in vitro on L1 but not N-CAM.

L1CAM NCAM1

8.35e-06210128071656
Pubmed

Homophilic NCAM interactions interfere with L1 stimulated neurite outgrowth.

L1CAM NCAM1

8.35e-062101210611478
Pubmed

Universal expression of cell adhesion molecule NCAM in neuroblastoma in contrast to L1: implications for different roles in tumor biology of neuroblastoma?

L1CAM NCAM1

8.35e-062101218972120
Pubmed

Piezo1 in Smooth Muscle Cells Is Involved in Hypertension-Dependent Arterial Remodeling.

FLNA PIEZO1

8.35e-062101226526998
Pubmed

Molecular cloning of cDNA encoding the rat neural cell adhesion molecule L1. Two L1 isoforms in the cytoplasmic region are produced by differential splicing.

L1CAM NCAM1

8.35e-06210121894011
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

MIER2 SYNM CIP2A SIPA1L3 SEMA4C PTCD1 SCAPER HECTD1 UNC80

1.42e-05493101915368895
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

FLNA PHRF1 CHD8 RPSA GANAB AHNAK BOP1 SPEN PLOD1 HECTD1

2.11e-056531011022586326
Pubmed

Sr2+ binding to the Ca2+ binding site of the synaptotagmin 1 C2B domain triggers fast exocytosis without stimulating SNARE interactions.

SYT3 SYT7

2.50e-053101212526776
Pubmed

A novel alternatively spliced variant of synaptotagmin VI lacking a transmembrane domain. Implications for distinct functions of the two isoforms.

SYT6 SYT5

2.50e-053101210531344
Pubmed

Polysialylated neural cell adhesion molecule is involved in induction of long-term potentiation and memory acquisition and consolidation in a fear-conditioning paradigm.

L1CAM NCAM1

2.50e-053101217050727
Pubmed

The clinical variability of the MECP2 duplication syndrome: description of two families with duplications excluding L1CAM and FLNA.

FLNA L1CAM

2.50e-053101219018795
Pubmed

Metalloelastase in lungs and alveolar macrophages is modulated by extracellular substance P in mice.

TACR1 MMP12

2.50e-053101218441096
Pubmed

An extended genome-wide association study identifies novel susceptibility loci for nasopharyngeal carcinoma.

CLPTM1L CIITA

2.50e-053101227436580
Pubmed

Myotubularin related protein-2 and its phospholipid substrate PIP2 control Piezo2-mediated mechanotransduction in peripheral sensory neurons.

PIEZO1 MTMR2

2.50e-053101229521261
Pubmed

Evidence for cis interaction and cooperative signalling by the heat-stable antigen nectadrin (murine CD24) and the cell adhesion molecule L1 in neurons.

L1CAM NCAM1

2.50e-05310127613634
Pubmed

Distribution of RA175/TSLC1/SynCAM, a member of the immunoglobulin superfamily, in the developing nervous system.

L1CAM NCAM1

4.99e-054101215707673
Pubmed

M-cadherin distribution in the mouse adult neuromuscular system suggests a role in muscle innervation.

L1CAM CHRNA1

4.99e-05410128921257
Pubmed

NCAM1, TACR1 and NOS genes and temperament: a study on suicide attempters and controls.

NCAM1 TACR1

4.99e-054101221577011
Pubmed

Expression of four immunoglobulin superfamily adhesion molecules (L1, Nr-CAM/Bravo, neurofascin/ABGP, and N-CAM) in the developing mouse spinal cord.

L1CAM NCAM1

4.99e-05410127706555
Pubmed

Synaptotagmin-mediated vesicle fusion regulates cell migration.

SYT7 SYT5

4.99e-054101220473299
Pubmed

The mouse Brachyury gene and mesoderm formation.

SYT3 SYT5

8.30e-05510122132728
Pubmed

Chromodomain helicase binding protein 8 (Chd8) is a novel A-kinase anchoring protein expressed during rat cardiac development.

SYNM CHD8

8.30e-055101223071553
Pubmed

A molecular mechanism for LINC complex branching by structurally diverse SUN-KASH 6:6 assemblies.

SYNE1 KASH5

8.30e-055101233393904
Pubmed

The cardiac actin locus (Actc-1) is not on mouse chromosome 17 but is linked to beta 2-microglobulin on chromosome 2.

CHRNA1 HDC

8.30e-05510122570027
Pubmed

Netrin-1 and DCC mediate axon guidance locally at the optic disc: loss of function leads to optic nerve hypoplasia.

L1CAM NCAM1

8.30e-05510129331350
Pubmed

Cross-reactivity of anti-programmed death ligand 2 polyclonal antibody in mouse tissues.

NCAM1 BTNL2

8.30e-055101223090063
Pubmed

A combination of chain and neurophilic migration involving the adhesion molecule TAG-1 in the caudal medulla.

L1CAM NCAM1

8.30e-055101211807022
Pubmed

Expression of distinct splice variants of the stem cell marker prominin-1 (CD133) in glial cells.

L1CAM NCAM1

8.30e-055101219053060
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

FLNA PIEZO1 SIPA1L3 L1CAM FGFRL1 CHD8 RPSA TXNRD2 AHNAK SPEN HECTD1 ANKRD33B

8.83e-0511051011235748872
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

SYNE1 PIEZO1 SIPA1L3 PHRF1 HLA-G CHD8 RPSA SYT7 SEMA4C SRRT CLPTM1L PTCD1 BOP1 SPEN

1.09e-0414971011431527615
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

CDC42BPG DGKA CHD8 CHD3 STAT5B PHKA2 SRRT CLPTM1L USP33

1.19e-04650101938777146
Pubmed

Expression of connexins in the developing olfactory system of the mouse.

L1CAM NCAM1

1.24e-04610121332989
Pubmed

Coordinate expression of L1 and 6B4 proteoglycan/phosphacan is correlated with the migration of mesencephalic dopaminergic neurons in mice.

L1CAM NCAM1

1.24e-04610129593903
Pubmed

p59fyn and pp60c-src modulate axonal guidance in the developing mouse olfactory pathway.

L1CAM NCAM1

1.24e-04610129658338
Pubmed

Chromosomal localization of three mouse diacylglycerol kinase (DAGK) genes: genes sharing sequence homology to the Drosophila retinal degeneration A (rdgA) gene.

DGKA CHRNA1

1.24e-04610127607687
Pubmed

Structural Analysis of Different LINC Complexes Reveals Distinct Binding Modes.

SYNE1 KASH5

1.24e-046101233058875
Pubmed

Transcription factors LRF and BCL11A independently repress expression of fetal hemoglobin.

CHD8 CHD3

1.74e-047101226816381
Pubmed

Pax3: a paired domain gene as a regulator in PNS myelination.

L1CAM NCAM1

1.74e-04710127546735
Pubmed

Defect of tyrosine hydroxylase-immunoreactive neurons in the brains of mice lacking the transcription factor Pax6.

L1CAM NCAM1

1.74e-047101210964956
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

FLNA SYNE1 RPSA CHD3 ZNF512B SRRT GANAB AHNAK BOP1 SPEN PLOD1

1.94e-0410241011124711643
Pubmed

The contribution of Notch1 to nephron segmentation in the developing kidney is revealed in a sensitized Notch2 background and can be augmented by reducing Mint dosage.

NCAM1 SPEN

2.31e-048101219914235
Pubmed

Evolution of the mouse t haplotype: recent and worldwide introgression to Mus musculus.

SYT3 SYT5

2.31e-04810121495973
Pubmed

Distinct adhesive behaviors of neurons and neural precursor cells during regional differentiation in the mammalian forebrain.

L1CAM NCAM1

2.31e-04810127750641
Pubmed

Ryk-mediated Wnt repulsion regulates posterior-directed growth of corticospinal tract.

L1CAM NCAM1

2.31e-048101216116452
Pubmed

Ca(2+)-dependent and -independent activities of neural and non-neural synaptotagmins.

SYT3 SYT6

2.31e-04810127791877
Pubmed

Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

ZNF492 CIP2A PHRF1 SCAPER

2.38e-04103101410819331
Pubmed

NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.

CHD3 ZNF512B SRRT SPEN

2.38e-04103101432744500
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

FLNA SYT3 SYNE1 SIPA1L3 L1CAM NCAM1 RPSA CHD3 PITPNM1 SRRT NGEF SCAPER MTMR2

2.59e-0414311011337142655
Pubmed

TWIST1 and chromatin regulatory proteins interact to guide neural crest cell differentiation.

CHD8 NGEF BOP1 SPEN

2.95e-04109101433554859
Pubmed

43K protein and acetylcholine receptors colocalize during the initial stages of neuromuscular synapse formation in vivo.

NCAM1 CHRNA1

2.97e-04910128416841
Pubmed

Fezf1 and Fezf2 are required for olfactory development and sensory neuron identity.

L1CAM NCAM1

2.97e-049101221452247
Pubmed

An MHC class Ib-restricted CD8+ T cell response to lymphocytic choriomeningitis virus.

HLA-G CIITA

2.97e-049101222084437
Pubmed

Pivotal roles of CD8+ T cells restricted by MHC class I-like molecules in autoimmune diseases.

HLA-G CIITA

2.97e-049101217088432
Pubmed

Mirror image motifs mediate the interaction of the COOH terminus of multiple synaptotagmins with the neurexins and calmodulin.

SYT6 SYT5

2.97e-04910128901523
Pubmed

Polyclonal MHC Ib-restricted CD8+ T cells undergo homeostatic expansion in the absence of conventional MHC-restricted T cells.

HLA-G CIITA

2.97e-049101218292501
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

DOCK11 CHD8 SRRT BOP1 NKTR PLOD1 HECTD1

3.06e-04440101734244565
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

FLNA RPSA CLPTM1L AHNAK HECTD1

3.17e-04202101533005030
Pubmed

Deltex3 inhibits Epithelial Mesenchymal Transition in Papillary Thyroid Carcinoma via promoting ubiquitination of XRCC5 to regulate the AKT signal pathway.

FLNA GANAB AHNAK

3.30e-0446101333403043
Pubmed

Dysphagia and disrupted cranial nerve development in a mouse model of DiGeorge (22q11) deletion syndrome.

L1CAM NCAM1 TXNRD2

3.51e-0447101324357327
Pubmed

Proteolytic cleavage of transmembrane cell adhesion molecule L1 by extracellular matrix molecule Reelin is important for mouse brain development.

L1CAM NCAM1

3.70e-0410101229127326
Pubmed

SIRT1 regulates Tat-induced HIV-1 transactivation through activating AMP-activated protein kinase.

ACACB PRKAG3

3.70e-0410101219720090
Pubmed

The NF-κB1 transcription factor prevents the intrathymic development of CD8 T cells with memory properties.

MAP3K8 HLA-G

3.70e-0410101222124325
Pubmed

Molecular mechanisms and regulation of insulin exocytosis as a paradigm of endocrine secretion.

SYT3 SYT5

3.70e-041010129914469
Pubmed

Widespread neuronal ectopia associated with secondary defects in cerebrocortical chondroitin sulfate proteoglycans and basal lamina in MARCKS-deficient mice.

L1CAM NCAM1

3.70e-041010129184108
Pubmed

Ubiquitin-specific protease 2a promotes hepatocellular carcinoma progression via deubiquitination and stabilization of RAB1A.

SRRT AHNAK

3.70e-0410101233074477
Pubmed

High-Confidence Interactome for RNF41 Built on Multiple Orthogonal Assays.

FLNA SIPA1L3 AHNAK

4.22e-0450101329560723
Pubmed

Thalamocortical pathfinding defects precede degeneration of the reticular thalamic nucleus in polysialic acid-deficient mice.

L1CAM NCAM1

4.51e-0411101221273415
Pubmed

Fingerprinting genomes by use of PCR with primers that encode protein motifs or contain sequences that regulate gene expression.

NCAM1 HDC

4.51e-041110121421760
Pubmed

Peripheral nervous system defects in erbB2 mutants following genetic rescue of heart development.

L1CAM CHRNA1

4.51e-0411101210521398
Pubmed

A conserved KASH domain protein associates with telomeres, SUN1, and dynactin during mammalian meiosis.

SYNE1 KASH5

4.51e-0411101222826121
Pubmed

Disruption of laminin in the peripheral nervous system impedes nonmyelinating Schwann cell development and impairs nociceptive sensory function.

L1CAM NCAM1

4.51e-0411101219053061
Pubmed

circPDE4B prevents articular cartilage degeneration and promotes repair by acting as a scaffold for RIC8A and MID1.

FLNA RPSA PLOD1

4.74e-0452101334039624
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

SYT3 DOCK11 SYT6 CHD8 SRRT NGEF BOP1

4.84e-04475101731040226
Pubmed

HDAC1/NFκB pathway is involved in curcumin inhibiting of Tat-mediated long terminal repeat transactivation.

ACACB PRKAG3

5.41e-0412101221344388
Pubmed

The intracellular redox protein MICAL-1 regulates the development of hippocampal mossy fibre connections.

L1CAM NCAM1

5.41e-0412101225007825
Pubmed

The adhesion molecule TAG-1 is required for proper migration of the superficial migratory stream in the medulla but not of cortical interneurons.

L1CAM NCAM1

5.41e-0412101216225856
Pubmed

Multiple influences on the migration of precerebellar neurons in the caudal medulla.

NCAM1 SEMA4C

5.41e-0412101211807023
Pubmed

Distribution and function of laminins in the neuromuscular system of developing, adult, and mutant mice.

NCAM1 CHRNA1

5.41e-041210129396756
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

FLNA ACACB SYNE1 AHNAK NGEF

6.19e-04234101536243803
Pubmed

PCR-analyzed microsatellites: data concerning laboratory and wild-derived mouse inbred strains.

HLA-G NCAM1

6.38e-041310121794054
Pubmed

Phylogenetic relationships among laboratory and wild-origin Mus musculus strains on the basis of genomic DNA RFLPs.

NCAM1 CHRNA1

6.38e-041310127906967
Pubmed

Pioneering axons regulate neuronal polarization in the developing cerebral cortex.

L1CAM NCAM1

6.38e-0413101224559674
Pubmed

Genomic analysis of synaptotagmin genes.

SYT3 SYT6

6.38e-0413101211543631
InteractionSYT10 interactions

SYT3 SYT6 BOP1

2.28e-066993int:SYT10
GeneFamilySynaptotagmins

SYT3 SYT6 SYT7 SYT5

3.08e-0717634765
ToppCellLPS_only-Epithelial_airway-Ciliated_cells-Ciliated|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RIBC2 DNAH1 SLC9A4 SYT5 CFAP161 CFAP99

1.41e-0615410169ca71d440c4f87781e6525b8141e7d8d470b6a8e
ToppCellLPS_only-Epithelial_airway-Ciliated_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RIBC2 DNAH1 SLC9A4 SYT5 CFAP161 CFAP99

1.41e-06154101658072ce422d09f2de602580325eaac6c4ec6c136
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RIBC2 SYT6 DNAH1 SLC9A4 CFAP161 CFAP99

2.04e-061641016e4d4c59aebe5cacd4ecdb907facd044dc82a831d
ToppCellCOVID-19_Mild-gd_T|COVID-19_Mild / Disease condition and Cell class

FLNA MAP3K8 SYNE1 HLA-G AHNAK AADACL2

3.84e-061831016f593a89b0aa8fffdfa403769916facfd30358521
ToppCellCiliated-cil-3|World / Class top

CFAP251 SYNE1 DNAH1 SYT5 CFAP161 HDC

5.06e-0619210164989ebb8812b8af1870599acd932849122c05a29
ToppCellFibroblasts-DKK3+_Fibroblasts|Fibroblasts / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

CRISPLD2 PAMR1 DOCK11 AHNAK NGEF DYRK2

5.69e-06196101624d64b67aa9b0e8215ad06f9101c1314b3483620
ToppCellCOVID_non-vent-Lymphocytic|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

SYNE1 DGKA RPSA CHD3 NKTR DYRK2

5.86e-061971016c672915f8c8c1e948d251f6eaf9f84a5600c1193
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_ciliated-Deuterosomal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

RIBC2 DNAH1 NGEF SYT5 CFAP161 CFAP99

5.86e-0619710166e4a411ef823ce9e16f420e185e21fa19d13af34
ToppCellCOVID_vent-Lymphocytic-T_cell|COVID_vent / Disease condition, Lineage, Cell class and subclass

SYNE1 DGKA RPSA CHD3 STAT5B DYRK2

5.86e-061971016ad702e440a74d54cfdcb8bb1c66bd8e0e71ab04e
ToppCellLPS_anti-TNF-Epithelial_airway-airway_epithelial-Ciliated|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

MMS22L RIBC2 DNAH1 SLC9A4 SYT5 CFAP161

6.21e-06199101615f7814b7074170eee7ccacaa670b1d128fc68bb
ToppCellhealthy_donor-Lymphocytic|healthy_donor / Disease condition, Lineage, Cell class and subclass

SYNE1 DGKA NCAM1 RPSA CHD3 DYRK2

6.21e-0619910162841e16d54acd344ba454f024e285c28abc37319
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Pericyte-Pericyte_3|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

CRISPLD2 FLNA SYNM DOCK11 SYNE1 NCAM1

6.39e-062001016a3a1e35934d676c39f917652e50c502cb2f613c1
ToppCellLPS_IL1RA-Epithelial_airway-airway_epithelial-Ciliated|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

RIBC2 DNAH1 SLC9A4 SYT5 CFAP161 CFAP99

6.39e-0620010164992dbf0514d674017315dbd20d91dfec0c608e9
ToppCellLPS-IL1RA-Epithelial_airway-Ciliated_cells|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RIBC2 DNAH1 SYT5 CFAP161 CFAP99

2.43e-05151101581cf939ed4df9574fbfff265e109cb9f947d7e6e
ToppCellLPS-IL1RA-Epithelial_airway-Ciliated_cells-Ciliated|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RIBC2 DNAH1 SYT5 CFAP161 CFAP99

2.43e-0515110159cbcbbc22965a9f0be8364e733d205dd64f2a533
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RIBC2 DNAH1 SLC9A4 CFAP161 CFAP99

2.76e-0515510155f1e2195a6b831e1b636f5cc3a282ca423721822
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells-Ciliated|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RIBC2 DNAH1 SLC9A4 CFAP161 CFAP99

2.76e-0515510150944429459f642a1bcc56edc1ec28aaecde3e2dc
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c11-GNLY|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

FLNA SYNE1 ZBTB22 HLA-G SEMA4C

3.12e-05159101557df5c9b678a15eb5e025e1a80de2e6769cc13d5
ToppCellThalamus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)|Thalamus / BrainAtlas - Mouse McCarroll V32

SYT6 DNAH1 KASH5 SYT5 TACR1

3.31e-0516110150605134a342d74ae81f33700d6ddfcd6e03aeb7b
ToppCellHippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)|Hippocampus / BrainAtlas - Mouse McCarroll V32

PAMR1 EVPL DNAH1 NGEF SYT5

3.31e-05161101566554f59eaea4ba55a6c6724f9368e24e99c91e9
ToppCellPBMC-Severe-cDC_1|Severe / Compartment, Disease Groups and Clusters

LGALS9C FLNA AHNAK MOCS1

3.49e-058110146d1e524f000b71c935359afc801a1d31f218fec8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF492 MMS22L RIBC2 BARD1 CDT1

3.94e-051671015108ae6221c6edc63c0ec42c42471b3a15a594043
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-FOXM1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MMS22L CIP2A AKR1D1 BARD1 CDT1

4.17e-051691015e0607af8ae8609d43e26ff2a2cab92650bfcd5b7
ToppCellNS-critical-LOC-Epithelial-FOXN4+|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

RIBC2 NGEF SYT5 CDT1 CFAP161

4.29e-051701015f6a0162bb690dbc19ff1cec64cb933744ad3b496
ToppCellMild_COVID-19-Myeloid-MoAM5|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）

CRISPLD2 SYNM CIP2A HLA-G ANKRD33B

4.29e-051701015b2daf46ab5a49590ede8f75e4240bfe6e9d8b764
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P5-P5_2|Striatum / BrainAtlas - Mouse McCarroll V32

MMS22L RPSA TKTL1 CDT1

4.41e-058610142df674969383d93509ea9e201452cfda702fae40
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P5-P5_2-Sox4|Striatum / BrainAtlas - Mouse McCarroll V32

MMS22L RPSA TKTL1 CDT1

4.41e-058610148ead39a100fa5aedf93a2206edd9828538f990a5
ToppCellfacs-Brain_Myeloid-Hippocampus-3m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMS22L L1CAM CIITA AHNAK SYT5

4.66e-051731015c63a615998d13b1725b5767f4ad2ec7e2b61db68
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 FLNA SYNE1 NCAM1 HDC

5.20e-051771015065bebd22031f143e90a407f952b444a3f8818c7
ToppCellfacs-Marrow-Granulocytes-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 FLNA SYNE1 NCAM1 HDC

5.20e-051771015eb304f20aab075bd17aa3aef819386c0e1a235bd
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

FLNA MAP3K8 SYNE1 SRRT AHNAK

5.20e-05177101584930899eb2978598bc8a351cbcd9e714e46799d
ToppCell15-Airway-Epithelial-Multiciliated_precursor|Airway / Age, Tissue, Lineage and Cell class

CFAP251 RIBC2 PITPNM1 SYT5 CFAP161

5.34e-051781015d8e0a696bdd6af6422d72af0413f9dbd6bc02afa
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAMR1 DGKA PALMD NGEF ANKRD33B

5.48e-0517910159ba8693fba2175bca9ff9735cc04e657abeb9084
ToppCellwk_15-18-Epithelial-Proximal_epithelial-Deuterosomal|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

RIBC2 PITPNM1 SYT5 CFAP161 CFAP99

5.93e-051821015000eca5baa6eb2335a1e6d76a13fff5382b0e150
ToppCellCV-Healthy-7|Healthy / Virus stimulation, Condition and Cluster

MMS22L TXNRD2 GAN TUBD1 ZNF681

6.41e-0518510151979d189c204f4c2893e3170a514ee7d5523406c
ToppCell18-Distal-Epithelial-Multiciliated_precursor|Distal / Age, Tissue, Lineage and Cell class

CFAP251 RIBC2 PITPNM1 SYT5 CFAP161

6.57e-05186101558ab1360a1730655a5939295ba05997ac4a2d14e
ToppCellP15-Epithelial-airway_epithelial_cell-club_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

DNAH1 KASH5 SYT5 CFAP161 HDC

6.74e-051871015a70aaae32426e9ddb1cbfbd0e0db24ccc96b9f40
ToppCellP15-Epithelial-airway_epithelial_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

DNAH1 KASH5 SYT5 CFAP161 HDC

6.91e-051881015e3e71c0f2e374330620cb4d27638953ffa9f5298
ToppCellPND07-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP251 RIBC2 KASH5 SYT5 CFAP161

7.09e-051891015057d7a03fdbe779122b203619a6f947f49b84d28
ToppCellPND07-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP251 RIBC2 KASH5 SYT5 CFAP161

7.09e-0518910159f57a131902d23494bf389baf6e6e2d99f88b2c8
ToppCellPND07-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP251 RIBC2 KASH5 SYT5 CFAP161

7.09e-051891015e443b02502edaefa94567a9e8af5756e8e11ff30
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c06-TNF|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

FLNA MAP3K8 SYNE1 NCAM1 AHNAK

7.45e-05191101504faa7d2237e45418611153294eb6f7bb690cbde
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP251 RIBC2 PITPNM1 SYT5 CFAP161

7.45e-051911015a6c9df4cb4d09e0a91b3c8d7f3e091a7e95e6471
ToppCellsevere-low-quality_cells|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SYNE1 DGKA SLC9A4 SCAPER NKTR

7.82e-0519310159337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ZNF492 MMS22L RIBC2 CIP2A CDT1

8.02e-051941015590a9d4f054e6a3685daf752c9354650fcc7d18a
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c07-TYROBP|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

FLNA MAP3K8 SYNE1 NCAM1 TKTL1

8.02e-05194101552e09b14159b609af00264a8f38accf37ba8f464
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ZNF492 MMS22L RIBC2 CIP2A CDT1

8.21e-051951015cec7df321f372d05c94f97d6bb18891a5cc3dec3
ToppCellControl-CD8+_Tem|Control / Disease condition and Cell class

FLNA SYNM MAP3K8 SYNE1 AHNAK

8.21e-0519510157503b3e032f95b350a2782d28e4d412a8dc9ebcc
ToppCellCOVID_non-vent-Lymphocytic-T_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

DGKA RPSA CHD3 NKTR DYRK2

8.21e-0519510154bdedd924564a260841a9153604026b57487c83d
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ZNF492 MMS22L RIBC2 CIP2A CDT1

8.21e-051951015b65463a804fed2d9a3be9e528ca8b9c98469bc86
ToppCellT/NK_cells-CD56dim_NK_cell|World / Lineage and Cell class

LGALS9C FLNA MAP3K8 SYNE1 NCAM1

8.21e-0519510156124e87cb9061bf8918377fb4a79084079ddfc16
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ZNF492 MMS22L RIBC2 CIP2A CDT1

8.21e-05195101556d8734d020b3da08a5aa9e67999706a9e023a99
ToppCellCOVID-19_Severe-Lymphoid_T/NK-gd_T|COVID-19_Severe / Disease group, lineage and cell class

FLNA SYNE1 NCAM1 CHD3 AHNAK

8.21e-0519510159990440bda7fac5d00ef80444fab07459be625e1
ToppCell(1)_T_cells-(1)_T_CD8_CTL|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)

FLNA SYNM MAP3K8 SYNE1 AHNAK

8.41e-051961015ad9b0651cb2a15b750e453b2dcf782bca08b4fe7
ToppCellhealthy_donor-Lymphocytic-T_cell-CD8+_Memory_T_cell|healthy_donor / Disease condition, Lineage, Cell class and subclass

FLNA SYNM SYNE1 CHD3 AHNAK

8.41e-051961015af00c31612e4fe068e5fccae05368edba46bbd20
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ZNF492 MMS22L RIBC2 CIP2A CDT1

8.41e-051961015df366d76ea55f49e349d622effa57c1535df8400
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

FLNA SYNE1 NCAM1 CHD3 AHNAK

8.41e-051961015418e8e0a51c5cb60e3b903e7d2d800dc8b9f3d5c
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FLNA SYNE1 NCAM1 CHD3 AHNAK

8.41e-051961015581fc8c8d42005aacd7b401a2c9d1fc331fb4af7
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_ILC-NK_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

FLNA MAP3K8 SYNE1 NCAM1 AHNAK

8.41e-05196101508714b70ddaee7d11397c1dd4a287d412edd90f7
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

FLNA SYNE1 NCAM1 CHD3 AHNAK

8.41e-0519610156beaf0c2799424c59819b286fbb5c1a83d85e4d1
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FLNA SYNE1 NCAM1 CHD3 AHNAK

8.41e-051961015c35f2349dfe35baa845f790b9f31673dceac54c0
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_ILC|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

FLNA MAP3K8 SYNE1 NCAM1 AHNAK

8.41e-0519610155bcc959db7deb34d5a32d3464367d47d4945cdaf
ToppCell(05)_Ciliated|World / shred by cell type and Timepoint

CFAP251 SYNE1 SYT5 CFAP161 HDC

8.62e-051971015fee3cd16af8eea697cd64e8f64af505aaa2ac4b0
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

FLNA MAP3K8 SYNE1 NCAM1 AHNAK

8.62e-051971015f84263c5aaf3a5cd46d6e06358e8de6c6e6eaa3b
ToppCellsevere-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SYNE1 DGKA CHD3 SLC9A4 NKTR

8.62e-05197101557ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCellBronchial-NucSeq-Stromal-Peri/Epineurial_-NAF_epineurial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CRISPLD2 ACACB PITPNM1 PTCD1 ANKRD33B

8.62e-051971015dfeb4a0eb4dfba90f4a3e6ba31e0ab0e4aba5849
ToppCellCOVID_non-vent-Lymphocytic-T_cell-CD4+_Naive_T_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

DGKA RPSA CHD3 NKTR DYRK2

8.62e-051971015836dd8110d5689f944ad1d301def38c32278b5b5
ToppCell(2)_Fibroblasts-(24)_Fibro-5|(2)_Fibroblasts / Cell class and subclass of bone marrow stroma cells in homeostatis

CRISPLD2 PAMR1 SYNM PALMD AHNAK

8.62e-05197101583a4b79fbfa1cf63441dee4424c3b87c988287bf
ToppCell10x5'-Liver-Lymphocytic_T_CD8-Tem/emra_CD8|Liver / Manually curated celltypes from each tissue

FLNA SYNE1 RPSA SRRT AHNAK

8.83e-0519810152fc2a4638c458ae793ac090a29d27b75fc9e6af6
ToppCellproximal-Epithelial-Neuroendocrine|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PRLHR SYT7 PRAP1 SYT5 UNC80

8.83e-0519810155dea6078488d584513c0bdbf5bba54877310b54a
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_ciliated-Deuterosomal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CFAP251 RIBC2 AADACL2 SYT5 CFAP99

8.83e-051981015f31790442ef142f1c0c49bf3daf2d0efb193d2c9
ToppCellCOVID_vent-Lymphocytic|COVID_vent / Disease condition, Lineage, Cell class and subclass

SYNE1 DGKA RPSA CHD3 DYRK2

8.83e-051981015ee80f647317377081b4bd194ee2801f556b3a53b
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

FLNA MAP3K8 SYNE1 NCAM1 AHNAK

8.83e-051981015faeef749a4b4bdc7f3edb6923e0e248e8b92c9d0
ToppCellproximal-Epithelial-Neuroendocrine-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PRLHR SYT7 PRAP1 SYT5 UNC80

8.83e-05198101500ccf3020667cf2130bc354b441b65c0b1b0e862
ToppCellCOVID_vent-Lymphocytic-T_cell-CD4+_Memory_T_cell|COVID_vent / Disease condition, Lineage, Cell class and subclass

DGKA RPSA CHD3 STAT5B DYRK2

8.83e-05198101558f208b76cb0adcecdf632d92f92833a06f9bf71
ToppCellproximal-3-Epithelial-Neuroendocrine|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PRLHR SYT7 PRAP1 SYT5 UNC80

8.83e-051981015a6bc043faf68468d46bac441cf7447c236c7bae4
ToppCellLPS_only-Epithelial_airway-airway_epithelial|LPS_only / Treatment groups by lineage, cell group, cell type

RIBC2 SYT6 DNAH1 SLC9A4 GAN

8.83e-051981015e035380578c01b0243bfef29ca9b50cc17cce771
ToppCellLPS_only-Epithelial_airway|LPS_only / Treatment groups by lineage, cell group, cell type

RIBC2 SYT6 DNAH1 SLC9A4 GAN

8.83e-051981015ba090210392e001a3f7bdf09371b3f0e0c8c7ef3
ToppCellLPS_only-Epithelial_airway-airway_epithelial-Ciliated|LPS_only / Treatment groups by lineage, cell group, cell type

RIBC2 DNAH1 SLC9A4 CFAP161 TUBD1

8.83e-0519810156d90b541fde357fbb40f8f7d4e8628a48b679718
ToppCell(1)_Osterolineage_cells-(11)_OLC-2|(1)_Osterolineage_cells / Cell class and subclass of bone marrow stroma cells in homeostatis

CRISPLD2 SYNM SYNE1 AHNAK NGEF

8.83e-0519810159f9dcf23ffb333105263132d87b90095642294cf
ToppCellSigmoid-(1)_T_cell-(14)_Tcm|Sigmoid / shred on region, Cell_type, and subtype

LGALS9C SYNE1 DGKA SYT5 CDT1

9.04e-051991015ec454fa22fb7f50a947bdf4c4bb6f0ba13f62b4c
ToppCellCOVID_vent-Lymphocytic-T_cell-CD4+_Naive_T_cell|COVID_vent / Disease condition, Lineage, Cell class and subclass

DGKA RPSA CHD3 NKTR DYRK2

9.04e-051991015885bc902b6e2af0b61e452c4154160cd3f1cf98e
ToppCellSigmoid-T_cell-Tcm|Sigmoid / Region, Cell class and subclass

LGALS9C SYNE1 DGKA SYT5 CDT1

9.04e-051991015f7c729eaa3c8fd5a05cb6f79cac9b8f199c8092b
ToppCellBronchial-10x5prime-Immune_Myeloid-Myeloid-Megakaryocyte|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ZNF512B SYT5 TACR1 ANKRD33B HDC

9.04e-0519910156e7f7214317f2af2ba8523df9896f54b7294d58a
ToppCellBronchial-10x5prime-Immune_Myeloid-Myeloid|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ZNF512B SYT5 TACR1 ANKRD33B HDC

9.04e-0519910155f499595597c10857bba8272f62afe4d32d733ac
ToppCellLPS_IL1RA_TNF-Epithelial_airway-airway_epithelial-Ciliated|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

RIBC2 DNAH1 SLC9A4 CFAP161 CFAP99

9.25e-05200101596701a4d57753f5ec0dd5c7550054bbcc946bc5f
ToppCellLPS_IL1RA-Epithelial_airway-airway_epithelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

RIBC2 SYT6 SYT5 CFAP161 CFAP99

9.25e-052001015cf191104484bfb2b9f87de416b9453135f8833c1
ToppCellLPS_IL1RA_TNF-Epithelial_airway-airway_epithelial|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

RIBC2 SYT6 DNAH1 CFAP161 CFAP99

9.25e-052001015da12821e8a0657869ca0f75d351cce2d7605a505
ToppCellLPS_IL1RA-Epithelial_airway|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

RIBC2 SYT6 SYT5 CFAP161 CFAP99

9.25e-052001015a5ae33dd4dc1ff6e1a1eec22c4d523d5ab657607
ToppCellhealthy_donor|World / Disease condition, Lineage, Cell class and subclass

SYNE1 NCAM1 RPSA AHNAK NKTR

9.25e-052001015afd4d5609adaa470e3d880f8be4a4d55e162b3d6
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated|COVID-19_Mild / Disease, condition lineage and cell class

FLNA SYNE1 HLA-G NCAM1 AHNAK

9.25e-0520010152281debd86e5d92e8fe0397aec9ef670800f7471
ToppCellControl_saline-Mesenchymal_myocytic-Pericyte-Pericyte_3|Control_saline / Treatment groups by lineage, cell group, cell type

CRISPLD2 FLNA DOCK11 SYNE1 NCAM1

9.25e-052001015b0866b497aa71d06cef25f9a335fa584e95fa7e0
ToppCellCOVID-19-COVID-19_Severe-Lymphocyte-T/NK-gd_T|COVID-19_Severe / Disease, condition lineage and cell class

FLNA SYNE1 NCAM1 CHD3 AHNAK

9.25e-052001015f72bc3f6606ae77fe1b0a972e35b3ce0727804d9
ToppCellLPS_IL1RA_TNF-Epithelial_airway|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

RIBC2 SYT6 DNAH1 CFAP161 CFAP99

9.25e-05200101572c1d9eeaed4b3ee6b6c602e8aa29efc2e8744eb
ToppCell3'_v3-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8|bone_marrow / Manually curated celltypes from each tissue

SYNE1 NKTR TACR1 MMP12

1.66e-04121101419333a660800b583fa27b495c1f7828e6636a257
ToppCellCerebellum-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)|Cerebellum / BrainAtlas - Mouse McCarroll V32

GABRR2 SLC9A4 SYT5 TACR1

2.19e-041301014ab141d91988a5de6d092757377a53f7de3707556
ToppCellCerebellum-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6|Cerebellum / BrainAtlas - Mouse McCarroll V32

GABRR2 SLC9A4 SYT5 TACR1

2.19e-0413010143d81151ee1369d819843826fc6ac197d83255e1d
ToppCellLPS-IL1RA+antiTNF-Unknown-Endothelial|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PAMR1 BARD1 PALMD KDM4D

2.32e-04132101446c80eab16a70da9f363a9fbdf50bccab0b287d7
ToppCellLPS-IL1RA+antiTNF-Unknown|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PAMR1 BARD1 PALMD KDM4D

2.32e-041321014a022c3c41654166cb106f27dc54fa88e8c40f898
DrugParoxetine maleate [64006-44-6]; Down 200; 1uM; PC3; HT_HG-U133A

ACACB PIEZO1 CHD3 SEMA4C PITPNM1 CDT1 SPEN DYRK2

2.57e-0619710084556_DN
DrugAzaperone [1649-18-9]; Down 200; 12.2uM; MCF7; HT_HG-U133A

EVPL CHD3 CAMTA2 SRRT ARFRP1 NKTR USP33 DYRK2

2.57e-0619710087231_DN
Diseasehypothyroidism (biomarker_via_orthology)

L1CAM NCAM1 F7 PLOD1

1.32e-0480954DOID:1459 (biomarker_via_orthology)
Diseasehemoglobin measurement, mean corpuscular hemoglobin concentration

PIEZO1 CDT1

2.84e-048952EFO_0004509, EFO_0004528
DiseaseMacrocephaly

CHD8 CHD3

5.54e-0411952C0221355
Diseasebilirubin measurement

PIEZO1 SIPA1L3 CHD3 TKTL1 NGEF CDT1 MMP12

5.74e-04442957EFO_0004570
Diseaseforced expiratory volume, response to bronchodilator

MMS22L SYNE1 CHRNA1 AHNAK GAN MMP12 USP33

5.98e-04445957EFO_0004314, GO_0097366
Diseasechromosome 22q11.2 deletion syndrome, distal (implicated_via_orthology)

TXNRD2 TBX10

9.10e-0414952DOID:0060413 (implicated_via_orthology)
Diseasediverticular disease

CRISPLD2 MMS22L PIEZO1 ARFRP1 SCAPER

1.01e-03236955EFO_0009959
Diseasecongenital myasthenic syndrome (implicated_via_orthology)

CHRNA1 SYT5

1.20e-0316952DOID:3635 (implicated_via_orthology)
Diseaselevel of Phosphatidylcholine (16:0_20:4) in blood serum

SYT7 AHNAK

2.07e-0321952OBA_2045076
DiseaseMalignant neoplasm of breast

FLNA SYT3 RIBC2 SYNE1 BARD1 CLPTM1L ARFRP1 ACCS SPEN PLOD1

2.41e-0310749510C0006142
Diseaselevel of Phosphatidylcholine (17:0_20:4) in blood serum

SYT7 AHNAK

3.17e-0326952OBA_2045087

Protein segments in the cluster

PeptideGeneStartEntry
HAIKMGWIQPRRPRD

BOP1

261

Q14137
PWAMRRNQHMPLESR

AADACL2

261

Q6P093
APRRAELEMWLQGHP

CHD8

2331

Q9HCK8
HPERVRQGKVWKAPS

BARD1

746

Q99728
LERLPDPQRTHVMWA

ACCS

306

Q96QU6
MEPGLEHALRRTPSW

PRKAG3

1

Q9UGI9
HVPWRDMEGKTIPSS

BTNL2

391

Q9UIR0
GKLWATNHVPEMVRP

AKR1D1

86

P51857
RTWAMAKGLVQHPPR

CIITA

686

P33076
MVVPEDQLTRWHPRF

CDT1

321

Q9H211
MIPRSTWKGPERLAH

CAMTA2

691

O94983
VDVRGPDWHLKMPKI

AHNAK

3921

Q09666
PAIGTQKMELHVRWR

AASDH

746

Q4L235
RVEKPRNHWMLVTGN

CFAP161

256

Q6P656
VHARDPRRGMSPQEW

ANKRD33B

216

A6NCL7
MEGKLVVWDIHRPPS

CFAP251

466

Q8TBY9
REMPGGPVWRKHYIT

MMP12

101

P39900
RKSRGHELLWPAAPM

CDC42BPG

1306

Q6DT37
AHPEEGRKEPSMWLT

KASH5

431

Q8N6L0
RSPSTHVMPNWVRKV

CHRNA1

321

P02708
RWMLAGRPHPTLKGT

ACACB

2046

O00763
EPAHVKENWIDPLMR

CFAP99

141

D6REC4
QHEGLPEPLMLRWKQ

HLA-G

286

P17693
IERIIMPGVVHWQSP

HDC

61

P19113
HTPQKRLMTPWEESN

PALMD

341

Q9NP74
RHGVPDEMRKVESNW

MMS22L

366

Q6ZRQ5
PNRLHQVWLEPEGMD

MTO1

326

Q9Y2Z2
TRQKGTWGPEERKMH

LGALS9C

76

Q6DKI2
TLIHMQTGTPPWVKR

MAP3K8

316

P41279
GHPRPDITWMKDDQA

FGFRL1

176

Q8N441
NHVWLQPRVMRPTKP

CRISPLD2

261

Q9H0B8
VQKGWMPRESVLPHL

EVPL

1921

Q92817
KDDGQHMWRPKRFPR

DGKA

201

P23743
GENQLPVWMPTRHLK

HERVK_113

841

P63132
HRPQKPREGAWDMED

PHRF1

1426

Q9P1Y6
WKRGQDRAVVDHMEP

KDM4D

336

Q6B0I6
IRWNPRMKPQEPIHN

MTMR2

581

Q13614
HEIRLMAEGAPKWPK

L1CAM

126

P32004
HRVVPDRWKGMTQEQ

RIBC2

271

Q9H4K1
SWDPLHVQGLRPRMS

MOCS1

401

Q9NZB8
APRKGWTLMHPGRLT

PLOD1

691

Q02809
VKPPWMALRVEQRKH

PRDM9

101

Q9NQV7
AQPPIELLRQWMDHG

DNAH1

2306

Q9P2D7
EWMVKCVVRNVHRPP

ARFRP1

181

Q13795
DPPKDEKQGWRHVRI

HECTD1

1201

Q9ULT8
HVDLNPPSVREMLWG

DOCK11

416

Q5JSL3
MPAWGLEQRPHVAGK

CUSTOS

31

Q96C57
VPRKPVKHTAMVSWG

FLNA

736

P21333
WRHRELIMGEDPAQP

CHD3

681

Q12873
AHRMKRPWQGQVEPQ

GALT

46

P07902
WIELAPLSMPRINHG

GAN

306

Q9H2C0
LIHAMPGKPWRTEQT

CPPED1

91

Q9BRF8
DTHLRILGKPVMERW

GAMT

31

Q14353
DRPQPGWRESLKMRV

FMR1NB

51

Q8N0W7
WEVKKMSPGRHVIPS

SCAPER

171

Q9BY12
AVRMTPGQALRHPWL

DYRK2

521

Q92630
KRWTGQVEMPKPSHL

GABRR2

26

P28476
QGEERPRLWVMPNHQ

PRAP1

121

Q96NZ9
DRVPMGKVPHLWGQS

PHKA2

391

P46019
VKRRWHEMAGPQLPE

MIER2

246

Q8N344
RASPEPRWHLMGLVS

PAMR1

676

Q6UXH9
WLEEQHIPPMLRATG

INCA1

56

Q0VD86
VTARRNPLHNPWGME

INCA1

216

Q0VD86
RGTISREHPWEVMPD

RPSA

186

P08865
GREHWAEMLANPRKP

SYT3

546

Q9BQG1
HWADMLANPRRPIAQ

SYT5

356

O00445
RDHWNEMLAYPRKPI

SYT6

476

Q5T7P8
VKHWKDMIARPRQPV

SYT7

381

O43581
VAWPRKIAPHGQNMT

PRLHR

351

P49683
RSTGQPWQPDKMLHL

SYNE1

4741

Q8NF91
HIKLGPSEVWRTERM

SYNM

1126

O15061
TPPHWKEEMQRLRAY

NKTR

361

P30414
ETRDMPWKPGPHRVF

F7

31

P08709
WKRMIEARGIQPTQH

IQCA1L

706

A6NCM1
YQAHREGIPVMRPLW

GANAB

716

Q14697
SRVVCMIEWPEHPNK

TACR1

176

P25103
ALRMIHPIPADSWRN

NGEF

156

Q8N5V2
PLMEDAPQRLRWQAH

SGSM3

66

Q96HU1
RESMRKGHSLPWGKP

SLC9A4

636

Q6AI14
QESTMERQKPEPLWH

SIPA1L3

1211

O60292
VRNKHPTGWKRTEEP

SIPA1L3

1451

O60292
ELLGRPMDSQWIPHA

STAT5B

771

P51692
KHPLMEEQVGPRWSR

SEMA4C

396

Q9C0C4
HELSPPQKRMRRDWD

SRRT

71

Q9BXP5
PVSHWRPRLALNVMA

CLPTM1L

166

Q96KA5
YRQQETEHIPRKMPW

CIP2A

556

Q8TCG1
WKPEIRLPSGSDHVM

NCAM1

656

P13591
HPDSPAKGAQWMRQI

TBX10

151

O75333
WHGDIKKIMPDDPER

TRIM69

346

Q86WT6
TGRPDMQKHRVVAWL

PITPNM1

1066

O00562
NAKMEEGIDRHVWPP

TUBD1

306

Q9UJT1
MLPKEIQAWLQEHRP

ZSCAN2

101

Q7Z7L9
IHKMPTLRRQVEWEP

UNC80

2596

Q8N2C7
MVRETRHLWVGNLPE

SPEN

1

Q96T58
HGPEEWKLMFRIQQR

SPO16

96

Q5VVC0
HEAPGRWKPVAPRTM

PRAC2

66

D3DTV9
LEQEKEPWEPMRRHE

ZNF43

56

P17038
EKHRIWNHMDRPLPA

ZNF512B

156

Q96KM6
WNVKRHEMVAEPPVV

ZNF492

31

Q9P255
EVAQPVPHDWRKMAE

TXNRD2

116

Q9NNW7
EPWTRKRHRMVAEPP

ZNF681

61

Q96N22
MEHVSLPGTRLPRWA

PIEZO1

711

Q92508
QMEPEPKLWRGRRNT

PTCD1

121

O75127
WHAKPMPRERADAII

TKTL1

231

P51854
SRRVWSPPRVHKVEM

ZBTB22

611

O15209
MTELWHKSRPGSVVP

USP33

236

Q8TEY7