Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionacetylcholine-gated monoatomic cation-selective channel activity

CHRNB3 CHRND CHRNE

1.35e-04171203GO:0022848
GeneOntologyMolecularFunctionplus-end-directed microtubule motor activity

KIF1A KIF1B KIF14

1.35e-04171203GO:0008574
GeneOntologyBiologicalProcessexcitatory postsynaptic potential

SHANK1 SYNE1 CHRNB3 CHRND CHRNE NRXN1 BAIAP2

9.91e-061301187GO:0060079
GeneOntologyBiologicalProcessdense core granule localization

KIF1A KIF1B UNC13C CADPS2

1.87e-05281184GO:0032253
GeneOntologyBiologicalProcessregulation of double-strand break repair

SHLD2 RADX TEX15 PPP4R3B FANCB USP51 SMARCB1

2.11e-051461187GO:2000779
GeneOntologyBiologicalProcesschemical synaptic transmission, postsynaptic

SHANK1 SYNE1 CHRNB3 CHRND CHRNE NRXN1 BAIAP2

2.21e-051471187GO:0099565
GeneOntologyBiologicalProcesssecretory granule localization

KIF1A KIF1B UNC13C CADPS2

4.13e-05341184GO:0032252
GeneOntologyBiologicalProcessregulation of postsynaptic membrane potential

SHANK1 SYNE1 CHRNB3 CHRND CHRNE NRXN1 BAIAP2

8.01e-051801187GO:0060078
GeneOntologyBiologicalProcessregulation of double-strand break repair via homologous recombination

SHLD2 RADX TEX15 FANCB USP51

1.14e-04831185GO:0010569
GeneOntologyCellularComponentsynaptic membrane

SHANK1 IL31RA SYNE1 HIP1R NCSTN NECTIN3 CHRNB3 CHRND CHRNE NRXN1 ATP6AP2 UNC13C BAIAP2 CADPS2 ADGRL2

1.15e-0658311915GO:0097060
GeneOntologyCellularComponentvesicle membrane

DOC2A KIF1A COPG1 KIF1B SLC30A8 HIP1R NCSTN PTCH1 MREG COMMD1 EGF ATP11B ATP6AP2 ATP6V1D VPS13A UNC13C FRMPD3 CADPS2 SLC4A11 DOP1B NCKAP1L

1.74e-05132511921GO:0012506
GeneOntologyCellularComponentsecretory vesicle

DOC2A PDE4B KIF1A KIF1B SLC30A8 NCSTN BPIFA2 EGF ATP11B COMMD9 ATP6AP2 CCDC62 ATP6V1D VPS13A UNC13C FRMPD3 BAIAP2 CADPS2 KPNB1 NCKAP1L

2.37e-05124611920GO:0099503
GeneOntologyCellularComponentexcitatory synapse

SHANK1 PDE4B NRXN1 UNC13C BAIAP2 CADPS2

3.39e-051071196GO:0060076
GeneOntologyCellularComponentcytoplasmic vesicle membrane

DOC2A KIF1A COPG1 KIF1B SLC30A8 HIP1R NCSTN PTCH1 MREG COMMD1 EGF ATP11B ATP6AP2 ATP6V1D VPS13A UNC13C FRMPD3 CADPS2 DOP1B NCKAP1L

4.65e-05130711920GO:0030659
GeneOntologyCellularComponentsynaptic vesicle

DOC2A PDE4B KIF1A KIF1B NCSTN ATP6AP2 ATP6V1D UNC13C CADPS2

5.58e-053001199GO:0008021
GeneOntologyCellularComponentpostsynapse

SHANK1 PDE4B KIF1A SYNE1 UBE3B KIF1B HIP1R NECTIN3 CHRNB3 CHRND CHRNE IGF2BP1 ATP6AP2 BAIAP2 CADPS2 ADGRL2 AGAP2

6.40e-05101811917GO:0098794
GeneOntologyCellularComponentexocytic vesicle

DOC2A PDE4B KIF1A KIF1B NCSTN ATP6AP2 ATP6V1D UNC13C CADPS2

9.14e-053201199GO:0070382
GeneOntologyCellularComponentdendrite

SHANK1 PDE4B KIF1A SYNE1 KIF1B HIP1R NECTIN3 PTCH1 MAPK8IP3 IGF2BP1 NF1 PPP5C ATP6AP2 BAIAP2 AGAP2

1.08e-0485811915GO:0030425
GeneOntologyCellularComponentdendritic tree

SHANK1 PDE4B KIF1A SYNE1 KIF1B HIP1R NECTIN3 PTCH1 MAPK8IP3 IGF2BP1 NF1 PPP5C ATP6AP2 BAIAP2 AGAP2

1.11e-0486011915GO:0097447
GeneOntologyCellularComponentacetylcholine-gated channel complex

CHRNB3 CHRND CHRNE

1.38e-04181193GO:0005892
GeneOntologyCellularComponenttransport vesicle

DOC2A PDE4B KIF1A COPG1 KIF1B SLC30A8 NCSTN ATP6AP2 ATP6V1D UNC13C CADPS2

1.87e-0451911911GO:0030133
GeneOntologyCellularComponentneuron projection cytoplasm

KIF1A KIF1B HIP1R MAPK8IP3 BAIAP2

4.18e-041101195GO:0120111
GeneOntologyCellularComponentneuromuscular junction

CHRND CHRNE NRXN1 UNC13C PLS3

4.54e-041121195GO:0031594
GeneOntologyCellularComponentdendritic spine

SHANK1 PDE4B SYNE1 HIP1R IGF2BP1 ATP6AP2 BAIAP2

4.77e-042421197GO:0043197
GeneOntologyCellularComponentpresynapse

DOC2A PDE4B IL31RA KIF1A KIF1B NCSTN CHRNB3 NF1 NRXN1 ATP6AP2 ATP6V1D UNC13C BAIAP2 CADPS2

5.18e-0488611914GO:0098793
GeneOntologyCellularComponentpostsynaptic membrane

SHANK1 SYNE1 NECTIN3 CHRNB3 CHRND CHRNE ATP6AP2 CADPS2 ADGRL2

5.22e-044051199GO:0045211
GeneOntologyCellularComponentneuron spine

SHANK1 PDE4B SYNE1 HIP1R IGF2BP1 ATP6AP2 BAIAP2

5.38e-042471197GO:0044309
GeneOntologyCellularComponentsomatodendritic compartment

SHANK1 PDE4B KIF1A SYNE1 KIF1B HIP1R NECTIN3 PTCH1 MAPK8IP3 IGF2BP1 NF1 PPP5C NRXN1 ATP6AP2 VPS13A BAIAP2 AGAP2

5.85e-04122811917GO:0036477
GeneOntologyCellularComponentsecretory granule membrane

KIF1A SLC30A8 NCSTN ATP11B ATP6AP2 ATP6V1D FRMPD3 NCKAP1L

5.97e-043291198GO:0030667
GeneOntologyCellularComponentsecretory granule

KIF1A SLC30A8 NCSTN BPIFA2 EGF ATP11B COMMD9 ATP6AP2 CCDC62 ATP6V1D VPS13A FRMPD3 BAIAP2 KPNB1 NCKAP1L

6.43e-04101411915GO:0030141
GeneOntologyCellularComponentCul2-RING ubiquitin ligase complex

ZYG11A FEM1B COMMD1

2.43e-03471193GO:0031462
GeneOntologyCellularComponentkinesin complex

KIF1A KIF1B KIF14

2.74e-03491193GO:0005871
GeneOntologyCellularComponenttranscription preinitiation complex

ERCC3 RPRD2

3.21e-03151192GO:0097550
GeneOntologyCellularComponentproton-transporting two-sector ATPase complex

ATP5PO ATP6AP2 ATP6V1D

3.42e-03531193GO:0016469
GeneOntologyCellularComponentexocytic vesicle membrane

DOC2A KIF1B ATP6AP2 ATP6V1D UNC13C

3.62e-031791195GO:0099501
GeneOntologyCellularComponentsynaptic vesicle membrane

DOC2A KIF1B ATP6AP2 ATP6V1D UNC13C

3.62e-031791195GO:0030672
DomainARM-type_fold

RALGAPA1 MROH9 ZYG11A COPG1 BZW2 VEPH1 RANBP6 HEATR5A PPP4R3B NF1 EFR3B TARBP1 PPP6R3 KPNB1

3.42e-0833911914IPR016024
DomainARM-like

MROH9 ZYG11A COPG1 RANBP6 HEATR5A PPP4R3B NF1 EFR3B TARBP1 PPP6R3 KPNB1

1.25e-0627011911IPR011989
DomainKinesin_assoc

KIF1A KIF1B KIF14

4.97e-0661193PF16183
DomainKinesin_assoc

KIF1A KIF1B KIF14

4.97e-0661193IPR032405
DomainRelaxin_rcpt

RXFP2 RXFP1

4.03e-0521192IPR008112
Domain-

MROH9 ZYG11A COPG1 RANBP6 HEATR5A NF1 EFR3B KPNB1

8.89e-0522211981.25.10.10
DomainNicotinic_acetylcholine_rcpt

CHRNB3 CHRND CHRNE

1.33e-04161193IPR002394
DomainKinesin-like_KIF1-typ

KIF1A KIF1B

2.40e-0441192IPR022140
DomainKIF1B

KIF1A KIF1B

2.40e-0441192PF12423
DomainDUF1041

UNC13C CADPS2

3.98e-0451192SM01145
Domain-

CHRNB3 CHRND CHRNE

4.07e-042311931.20.120.370
DomainAcetylcholine_rcpt_TM

CHRNB3 CHRND CHRNE

4.07e-04231193IPR027361
DomainDUF3694

KIF1A KIF1B

5.94e-0461192PF12473
DomainKinesin-like

KIF1A KIF1B

5.94e-0461192IPR022164
DomainFHA

KIF1A KIF1B KIF14

7.35e-04281193SM00240
DomainDUF1041

UNC13C CADPS2

8.28e-0471192PF06292
DomainMunc13_1

UNC13C CADPS2

8.28e-0471192IPR014770
DomainCAPS_dom

UNC13C CADPS2

8.28e-0471192IPR010439
DomainMHD1

UNC13C CADPS2

8.28e-0471192PS51258
DomainFHA_DOMAIN

KIF1A KIF1B KIF14

9.95e-04311193PS50006
DomainFHA

KIF1A KIF1B KIF14

9.95e-04311193PF00498
DomainHEAT_REPEAT

COPG1 RANBP6 HEATR5A KPNB1

1.04e-03701194PS50077
DomainFHA_dom

KIF1A KIF1B KIF14

1.54e-03361193IPR000253
Domain-

KIF1A KIF1B KIF14

1.54e-033611932.60.200.20
DomainCOMM

COMMD1 COMMD9

1.75e-03101192IPR017920
DomainCOMM_domain

COMMD1 COMMD9

1.75e-03101192PF07258
DomainCOMM

COMMD1 COMMD9

1.75e-03101192PS51269
DomainKinesin_motor_CS

KIF1A KIF1B KIF14

2.25e-03411193IPR019821
DomainKinesin-like_fam

KIF1A KIF1B KIF14

2.58e-03431193IPR027640
DomainKINESIN_MOTOR_1

KIF1A KIF1B KIF14

2.76e-03441193PS00411
Domain-

KIF1A KIF1B KIF14

2.76e-034411933.40.850.10
DomainKinesin_motor_dom

KIF1A KIF1B KIF14

2.76e-03441193IPR001752
DomainKinesin

KIF1A KIF1B KIF14

2.76e-03441193PF00225
DomainKINESIN_MOTOR_2

KIF1A KIF1B KIF14

2.76e-03441193PS50067
DomainKISc

KIF1A KIF1B KIF14

2.76e-03441193SM00129
DomainNeurotransmitter_ion_chnl_CS

CHRNB3 CHRND CHRNE

2.94e-03451193IPR018000
DomainNeur_chan_memb

CHRNB3 CHRND CHRNE

3.14e-03461193PF02932
DomainNeur_chan_LBD

CHRNB3 CHRND CHRNE

3.33e-03471193PF02931
DomainNEUROTR_ION_CHANNEL

CHRNB3 CHRND CHRNE

3.33e-03471193PS00236
DomainNeurotrans-gated_channel_TM

CHRNB3 CHRND CHRNE

3.33e-03471193IPR006029
Domain-

CHRNB3 CHRND CHRNE

3.33e-034711932.70.170.10
DomainNeur_channel

CHRNB3 CHRND CHRNE

3.33e-03471193IPR006201
DomainNeur_chan_lig-bd

CHRNB3 CHRND CHRNE

3.33e-03471193IPR006202
DomainRasGAP

NF1 IQGAP3

3.48e-03141192SM00323
DomainRasGAP_CS

NF1 IQGAP3

3.48e-03141192IPR023152
DomainRasGAP

NF1 IQGAP3

4.00e-03151192PF00616
DomainRAS_GTPASE_ACTIV_1

NF1 IQGAP3

4.00e-03151192PS00509
DomainRAS_GTPASE_ACTIV_2

NF1 IQGAP3

4.00e-03151192PS50018
DomainSMAD_FHA_domain

KIF1A KIF1B KIF14

4.44e-03521193IPR008984
DomainRasGAP_dom

NF1 IQGAP3

5.76e-03181192IPR001936
DomainPH_dom-like

KIF1A MYO7B KIF1B VEPH1 PPP4R3B FRMPD3 CADPS2 AGAP2

5.96e-034261198IPR011993
PathwayREACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS

CHRNB3 CHRND CHRNE

4.80e-0512873M48008
PathwayREACTOME_ACETYLCHOLINE_BINDING_AND_DOWNSTREAM_EVENTS

CHRNB3 CHRND CHRNE

7.87e-0514873M757
PathwayREACTOME_ACETYLCHOLINE_BINDING_AND_DOWNSTREAM_EVENTS

CHRNB3 CHRND CHRNE

9.79e-0515873MM14704
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

TPTE ATP5PO KIF1A COPG1 BZW2 RANBP6 NCSTN SLC1A5 PGM3 LUZP1 IGF2BP1 PPP5C ATP6AP2 ADGRL2 PLS3 PPP6R3 KPNB1

5.04e-089741211728675297
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

ATP5PO KIF1A COPG1 BZW2 RANBP6 NCSTN SLC1A5 PGM3 ATP6AP2 RFT1 ADGRL2 TARBP1 IQGAP3 PPP6R3 KPNB1

1.04e-069421211531073040
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

RALGAPA1 SANBR HIP1R NCSTN PPP4R3B ATP11B MED12L EFR3B RPRD2 ADGRL2 PPP6R3

2.57e-065291211114621295
Pubmed

Discovery of tissue-specific exons using comprehensive human exon microarrays.

DYM ATP11B ADGRL2

3.40e-069121317456239
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

RALGAPA1 TPTE BZW2 SLC1A5 LUZP1 CDCA2 PPP4R3B PPP5C VPS13A EFR3B KIF14 BAIAP2 ADGRL2 PPP6R3 KPNB1

3.86e-0610491211527880917
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

TRPM6 ATP5PO KIF1A COPG1 SYNE1 SLC1A5 CDCA2 IGF2BP1 NF1 PPP5C PWP2 UBA6 KIF14 PLS3 IQGAP3 MGAM2 KPNB1

9.24e-0614251211730948266
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

DYM ATP5PO ACADSB COPG1 BZW2 DDX60 RANBP6 SLC1A5 PGM3 IGF2BP1 COMMD1 COMMD9 KIF14 ADGRL2 PLS3 PPP6R3 KPNB1

1.06e-0514401211730833792
Pubmed

Aromatic Residues {epsilon}Trp-55 and {delta}Trp-57 and the Activation of Acetylcholine Receptor Channels.

CHRND CHRNE

1.20e-052121219171937
Pubmed

The single nucleotide polymorphism Rs12817488 is associated with Parkinson's disease in the Chinese population.

HIP1R CCDC62

1.20e-052121225818163
Pubmed

The neuron-specific kinesin superfamily protein KIF1A is a unique monomeric motor for anterograde axonal transport of synaptic vesicle precursors.

KIF1A KIF1B

1.20e-05212127539720
Pubmed

Relaxin increases human endothelial progenitor cell NO and migration and vasculogenesis in mice.

RXFP2 RXFP1

1.20e-052121222028476
Pubmed

Splice variants of the relaxin and INSL3 receptors reveal unanticipated molecular complexity.

RXFP2 RXFP1

1.20e-052121216051677
Pubmed

Feedback activation of neurofibromin terminates growth factor-induced Ras activation.

NF1 EGF

1.20e-052121226861207
Pubmed

The different ligand-binding modes of relaxin family peptide receptors RXFP1 and RXFP2.

RXFP2 RXFP1

1.20e-052121222973049
Pubmed

EGF increases TRPM6 activity and surface expression.

TRPM6 EGF

1.20e-052121219073827
Pubmed

KIF1B and NF1 are the most frequently mutated genes in paraganglioma and pheochromocytoma tumors.

KIF1B NF1

1.20e-052121228515046
Pubmed

Resolving the unconventional mechanisms underlying RXFP1 and RXFP2 receptor function.

RXFP2 RXFP1

1.20e-052121219416161
Pubmed

Modeling the primary hormone-binding site of RXFP1 and RXFP2.

RXFP2 RXFP1

1.20e-052121219416162
Pubmed

Characterization of novel splice variants of LGR7 and LGR8 reveals that receptor signaling is mediated by their unique low density lipoprotein class A modules.

RXFP2 RXFP1

1.20e-052121216963451
Pubmed

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.

RALGAPA1 ERCC3 DYM COPG1 BZW2 RADX STK3 COMMD1 COMMD9 ATP6AP2 PWP2 RFT1

1.34e-057541211233060197
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

ATP5PO BZW2 RADX UBE3B KIF1B PGM3 LUZP1 STK3 FANCB NF1 NRXN1 BAIAP2 RFT1 PLS3 IQGAP3 KPNB1

1.44e-0513211211627173435
Pubmed

Design and expression of human alpha7 nicotinic acetylcholine receptor extracellular domain mutants with enhanced solubility and ligand-binding properties.

CHRNB3 CHRND CHRNE

1.45e-0514121319059502
Pubmed

Analysis of nicotinic acetylcholine receptor subunits in the cochlea of the mouse.

CHRNB3 CHRND CHRNE

1.81e-051512138838678
Pubmed

SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis.

ATP5PO COPG1 RANBP6 NCSTN SLC1A5 NF1 ATP6AP2 VPS13A CADPS2 PPP6R3 KPNB1

1.96e-056571211136180527
Pubmed

Multiple distinct risk loci for nicotine dependence identified by dense coverage of the complete family of nicotinic receptor subunit (CHRN) genes.

CHRNB3 CHRND CHRNE

2.23e-0516121319259974
Pubmed

Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.

TPTE ATP5PO SYNE1 KIF1B CDCA2 PPP4R3B PPP5C PPP6R3 DOP1B KPNB1

3.36e-055731211028330616
Pubmed

A novel role for relaxin-2 in the pathogenesis of primary varicosis.

RXFP2 RXFP1

3.59e-053121222737225
Pubmed

Regulation of murine copper homeostasis by members of the COMMD protein family.

COMMD1 COMMD9

3.59e-053121233262129
Pubmed

BORC Functions Upstream of Kinesins 1 and 3 to Coordinate Regional Movement of Lysosomes along Different Microtubule Tracks.

KIF1A KIF1B

3.59e-053121227851960
Pubmed

Relaxin receptors 1 and 2 and nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) mRNAs are expressed in oral components of developing mice.

RXFP2 RXFP1

3.59e-053121224370181
Pubmed

Genetic association study between STK39 and CCDC62/HIP1R and Parkinson's disease.

HIP1R CCDC62

3.59e-053121224312176
Pubmed

Identification of key residues essential for the structural fold and receptor selectivity within the A-chain of human gene-2 (H2) relaxin.

RXFP2 RXFP1

3.59e-053121223024363
Pubmed

Generation of a mouse model of atypical teratoid/rhabdoid tumor of the central nervous system through combined deletion of Snf5 and p53.

PTCH1 SMARCB1

3.59e-053121226363008
Pubmed

Quantitative trait analysis of type 2 diabetes susceptibility loci identified from whole genome association studies in the Insulin Resistance Atherosclerosis Family Study.

SLC30A8 IGF2BP1

3.59e-053121218252897
Pubmed

In vivo optical trapping indicates kinesin's stall force is reduced by dynein during intracellular transport.

KIF1A KIF1B

3.59e-053121223404705
Pubmed

Rapsyn carboxyl terminal domains mediate muscle specific kinase-induced phosphorylation of the muscle acetylcholine receptor.

CHRND CHRNE

3.59e-053121218436384
Pubmed

Changes in mRNA expression of nicotinic acetylcholine receptor subunits during embryonic development of mouse masseter muscle.

CHRND CHRNE

3.59e-053121212012784
Pubmed

Activation of orphan receptors by the hormone relaxin.

RXFP2 RXFP1

3.59e-053121211809971
Pubmed

Structural Insights into the Unique Modes of Relaxin-Binding and Tethered-Agonist Mediated Activation of RXFP1 and RXFP2.

RXFP2 RXFP1

3.59e-053121234454945
Pubmed

Relaxin-3: improved synthesis strategy and demonstration of its high-affinity interaction with the relaxin receptor LGR7 both in vitro and in vivo.

RXFP2 RXFP1

3.59e-053121216411781
Pubmed

Regulation of Rxfp2 (Lgr8) expression in the mouse fetal kidney by the transcription factor Pod1 (Tcf 21).

RXFP2 RXFP1

3.59e-053121219416211
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

SHANK1 KIF1A SYNE1 KIF1B MAPK8IP3 PPP4R3B COMMD1 PPP5C BAIAP2 CADPS2 TARBP1 AGAP2 DOP1B ZNF292 KPNB1

4.16e-0512851211535914814
Pubmed

Targeting RICTOR Sensitizes SMAD4-Negative Colon Cancer to Irinotecan.

DIS3L2 ACADSB HIP1R NCSTN PGM3 UBA6

4.55e-05183121631932471
Pubmed

CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.

ACADSB RADX HIP1R RANBP6 TTK STK3 PPP4R3B VPS13A IQGAP3 PPP6R3

5.37e-056061211036538041
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

RALGAPA1 ATP5PO ACADSB SYNE1 TTK SLC1A5 PPP5C ATP6AP2 PWP2 VPS13A EFR3B UBA6 BAIAP2 ADGRL2 PLS3 PPP6R3

5.98e-0514871211633957083
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

SHANK1 RALGAPA1 SYNE1 LUZP1 NF1 BAIAP2 AGAP2

6.01e-05281121728706196
Pubmed

Function of interfacial prolines at the transmitter-binding sites of the neuromuscular acetylcholine receptor.

CHRND CHRNE

7.17e-054121223519471
Pubmed

Design and control of acetylcholine receptor conformational change.

CHRND CHRNE

7.17e-054121221368211
Pubmed

Developmental changes in the nicotinic acetylcholine receptor in mouse tongue striated muscle.

CHRND CHRNE

7.17e-054121211926244
Pubmed

Acetylcholine receptor assembly: subunit folding and oligomerization occur sequentially.

CHRND CHRNE

7.17e-05412128334706
Pubmed

Receptors for relaxin family peptides.

RXFP2 RXFP1

7.17e-054121215956688
Pubmed

The local anaesthetics proadifen and adiphenine inhibit nicotinic receptors by different molecular mechanisms.

CHRND CHRNE

7.17e-054121219422391
Pubmed

Ceramides modulate cell-surface acetylcholine receptor levels.

CHRND CHRNE

7.17e-054121218023270
Pubmed

The Molecular Motor KIF1A Transports the TrkA Neurotrophin Receptor and Is Essential for Sensory Neuron Survival and Function.

KIF1A KIF1B

7.17e-054121227263974
Pubmed

Prolonged RXFP1 and RXFP2 signaling can be explained by poor internalization and a lack of beta-arrestin recruitment.

RXFP2 RXFP1

7.17e-054121219279230
Pubmed

Peer smoking and the nicotinic receptor genes: an examination of genetic and environmental risks for nicotine dependence.

CHRNB3 CHRND

7.17e-054121220840187
Pubmed

Novel genes identified in a high-density genome wide association study for nicotine dependence.

CHRNB3 NRXN1

7.17e-054121217158188
Pubmed

New mutations in acetylcholine receptor subunit genes reveal heterogeneity in the slow-channel congenital myasthenic syndrome.

CHRND CHRNE

7.17e-05412128872460
Pubmed

The COMMD Family Regulates Plasma LDL Levels and Attenuates Atherosclerosis Through Stabilizing the CCC Complex in Endosomal LDLR Trafficking.

COMMD1 COMMD9

7.17e-054121229545368
Pubmed

Mutation of single murine acetylcholine receptor subunits reveals differential contribution of P121 to acetylcholine binding and channel opening.

CHRND CHRNE

7.17e-054121215864502
Pubmed

The ultrastructural localization and quantitation of cholinergic receptors at the mouse motor endplate.

CHRND CHRNE

7.17e-05412124781450
Pubmed

Microbial Sensing by Intestinal Myeloid Cells Controls Carcinogenesis and Epithelial Differentiation.

COMMD1 COMMD9

7.17e-054121230157428
Pubmed

International Union of Pharmacology LVII: recommendations for the nomenclature of receptors for relaxin family peptides.

RXFP2 RXFP1

7.17e-054121216507880
Pubmed

Somatic CRISPR/Cas9-mediated tumour suppressor disruption enables versatile brain tumour modelling.

PTCH1 NF1

7.17e-054121226067104
Pubmed

Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST.

KIF1A KIF1B NRXN1 ADGRL2 PPP6R3

8.82e-05128121530995482
Pubmed

Identification and classification of 16 new kinesin superfamily (KIF) proteins in mouse genome.

KIF1A KIF1B KIF14

8.93e-052512139275178
Pubmed

Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.

DDX60 LUZP1 CCDC62 VPS13A PLS3 IQGAP3

9.24e-05208121633230847
Pubmed

Systematic proteomics of the VCP-UBXD adaptor network identifies a role for UBXN10 in regulating ciliogenesis.

ERCC3 ACADSB RANBP6 PPP4R3B VPS13A PLS3

9.49e-05209121626389662
Pubmed

KIF1Bbeta- and KIF1A-mediated axonal transport of presynaptic regulator Rab3 occurs in a GTP-dependent manner through DENN/MADD.

KIF1A KIF1B

1.19e-045121218849981
Pubmed

Shh/Ptch and EGF/ErbB cooperatively regulate branching morphogenesis of fetal mouse submandibular glands.

PTCH1 EGF

1.19e-045121226930157
Pubmed

H3 relaxin is a specific ligand for LGR7 and activates the receptor by interacting with both the ectodomain and the exoloop 2.

RXFP2 RXFP1

1.19e-045121212506116
Pubmed

Multiple binding sites revealed by interaction of relaxin family peptides with native and chimeric relaxin family peptide receptors 1 and 2 (LGR7 and LGR8).

RXFP2 RXFP1

1.19e-045121215649866
Pubmed

Properties of embryonic and adult muscle acetylcholine receptors transiently expressed in COS cells.

CHRND CHRNE

1.19e-04512122383398
Pubmed

The A-chain of human relaxin family peptides has distinct roles in the binding and activation of the different relaxin family peptide receptors.

RXFP2 RXFP1

1.19e-045121218434306
Pubmed

The insulin receptor substrate IRSp53 links postsynaptic shank1 to the small G-protein cdc42.

SHANK1 BAIAP2

1.19e-045121212504591
Pubmed

RELAXIN enhances differentiation and matrix mineralization through Relaxin/insulin-like family peptide receptor 2 (Rxfp2) in MC3T3-E1 cells in vitro.

RXFP2 RXFP1

1.19e-045121224857857
Pubmed

Neuropathology of genetically engineered mice: consensus report and recommendations from an international forum.

PTCH1 NF1

1.19e-045121212386807
Pubmed

Insulin receptor substrate of 53 kDa links postsynaptic shank to PSD-95.

SHANK1 BAIAP2

1.19e-045121215255944
Pubmed

The C. elegans homolog of human panic-disorder risk gene TMEM132D orchestrates neuronal morphogenesis through the WAVE-regulatory complex.

SHLD2 COMMD1 TMEM132D CADPS2

1.19e-0472121433726789
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

SHANK1 PDE4B SYNE1 LUZP1 MAPK8IP3 NF1 NRXN1 UBA6 FRMPD3 BAIAP2 AGAP2 KPNB1

1.40e-049631211228671696
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

DOC2A ATP5PO SYNE1 SANBR CHRNB3 LUZP1 CDCA2 NRXN1 PWP2 VPS13A CADPS2 SLC4A11 AGAP2 ZNF292 KPNB1

1.50e-0414421211535575683
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

RALGAPA1 KIF1B LUZP1 STK3 NF1 KIF14 BAIAP2 PPP6R3

1.75e-04446121824255178
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

PNPLA4 MYO7B DDX60 SYNE1 TEX15 IGF2BP1

1.76e-04234121636243803
Pubmed

Melanoregulin, product of the dsu locus, links the BLOC-pathway and OA1 in organelle biogenesis.

HPS3 MREG

1.78e-046121222984402
Pubmed

Correlations among ERCC1, XPB, UBE2I, EGF, TAL2 and ILF3 revealed by gene signatures of histological subtypes of patients with epithelial ovarian cancer.

ERCC3 EGF

1.78e-046121221971700
Pubmed

Genetic targeting of relaxin and insulin-like factor 3 receptors in mice.

RXFP2 RXFP1

1.78e-046121215256493
Pubmed

The calcium-independent receptor for alpha-latrotoxin from human and rodent brains interacts with members of the ProSAP/SSTRIP/Shank family of multidomain proteins.

SHANK1 ADGRL2

1.78e-046121210964907
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

RALGAPA1 BZW2 KIF1B TTK SLC1A5 EFR3B UBA6 ADGRL2 PLS3 KPNB1

1.91e-047081211039231216
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

RALGAPA1 KIF1B TTK SLC1A5 LUZP1 CDCA2 STK3 NF1 KIF14 BAIAP2 DOP1B

2.17e-048611211136931259
Pubmed

Neuromuscular synapse formation in mice lacking motor neuron- and skeletal muscle-derived Neuregulin-1.

CHRND CHRNE

2.49e-047121216407563
Pubmed

Gene expression profiling in embryonic mouse lenses.

CCNT2 IGF2BP1

2.49e-047121217213798
Pubmed

Relaxin induces matrix-metalloproteinases-9 and -13 via RXFP1: induction of MMP-9 involves the PI3K, ERK, Akt and PKC-ζ pathways.

RXFP2 RXFP1

2.49e-047121222835547
Pubmed

A role for the calmodulin kinase II-related anchoring protein (αkap) in maintaining the stability of nicotinic acetylcholine receptors.

CHRND CHRNE

2.49e-047121222496563
Pubmed

Proteomic Analysis Reveals a Role for RSK in p120-catenin Phosphorylation and Melanoma Cell-Cell Adhesion.

KIF1A COPG1 RANBP6 SLC1A5 ADGRL2

2.50e-04160121531678930
Pubmed

Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.

SHANK1 PDE4B SYNE1 NRXN1 BAIAP2 AGAP2

2.56e-04251121627507650
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

PIGN ATP5PO BZW2 RANBP6 NCSTN NECTIN3 NF1 ATP6AP2 RFT1 SCARA3 PLS3 PPP6R3 CREB3L2

2.90e-0412011211335696571
Pubmed

All kinesin superfamily protein, KIF, genes in mouse and human.

KIF1A KIF1B KIF14

2.93e-0437121311416179
Pubmed

Control of neuronal precursor proliferation in the cerebellum by Sonic Hedgehog.

PTCH1 EGF

3.32e-048121210027293
Pubmed

Unconventional molecular regulation of synaptic vesicle replenishment in cochlear inner hair cells.

UNC13C CADPS2

3.32e-048121225609709
Pubmed

HIV-1 capsids bind and exploit the kinesin-1 adaptor FEZ1 for inward movement to the nucleus.

KIF1A KIF1B

3.32e-048121225818806
InteractionGYPA interactions

BZW2 HIP1R NF1 COMMD9 GYPA PWP2 KIF14 TARBP1 ZNF292

6.96e-071741159int:GYPA
InteractionSHANK1 interactions

SHANK1 KIF14 BAIAP2 ADGRL2 AGAP2

3.53e-06411155int:SHANK1
InteractionTNFSF13B interactions

DYM COPG1 BZW2 RANBP6 NF1 KIF14 KPNB1

5.42e-061191157int:TNFSF13B
InteractionSPHKAP interactions

EGF PPP5C NRXN1 KIF14

9.79e-06241154int:SPHKAP
InteractionABHD14A interactions

BZW2 PTCH1 PPP5C RXFP1 SCARA3

3.75e-05661155int:ABHD14A
InteractionRHOQ interactions

RALGAPA1 COPG1 NECTIN3 SLC1A5 NF1 VPS13A EFR3B KIF14 BAIAP2 ADGRL2 IQGAP3

4.58e-0544211511int:RHOQ
InteractionSLC27A2 interactions

DYM BZW2 RANBP6 NCSTN KIF14 KPNB1

5.14e-051151156int:SLC27A2
GeneFamilyCholinergic receptors nicotinic subunits

CHRNB3 CHRND CHRNE

4.15e-0516783173
GeneFamilyRelaxin family peptide receptors

RXFP2 RXFP1

1.10e-044782217
GeneFamilyCOMM domain containing

COMMD1 COMMD9

8.09e-0410782979
GeneFamilyKinesins|Pleckstrin homology domain containing

KIF1A KIF1B KIF14

1.03e-0346783622
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

KIF1A KIF1B VEPH1 CADPS2 AGAP2

1.97e-03206785682
GeneFamilyOlfactory receptors, family 10

OR10T2 OR10J5 OR10J4

2.91e-0366783157
CoexpressionGSE9509_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_20MIN_DN

ATP5PO TTK CDCA2 DDIAS FANCB KCTD6 KIF14 IQGAP3

3.40e-061971198M6901
CoexpressionAtlasdev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_500

ZYG11A TEX15 TTK MREG DDIAS FANCB SOHLH2 ATP11B VPS13A UBA6 KIF14 CPLANE1

8.36e-0738511112gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_500
CoexpressionAtlasdev gonad_e12.5_F_GermCellOvary_Oct_top-relative-expression-ranked_1000

ZYG11A DYM HEATR5A TEX15 TTK CDCA2 MREG DDIAS FANCB IGF2BP1 SOHLH2 ATP11B PPP5C VPS13A MED12L KIF14 CPLANE1

1.26e-0682211117gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_1000
CoexpressionAtlasdev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_1000

ZYG11A DYM TEX15 TTK MREG DDIAS FANCB SOHLH2 ATP11B PPP5C CCDC62 VPS13A MED12L UBA6 KIF14 CPLANE1

5.59e-0682011116gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_1000
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RALGAPA1 PIGN TTK DDIAS NF1 PWP2 KIF14 IQGAP3

2.64e-08174121872df66319f6efbd88ecf439013d97409fbf3cb52
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RALGAPA1 PIGN TTK DDIAS NF1 PWP2 KIF14 IQGAP3

2.64e-081741218c6087fd0e036ec7f40f0f8f17d1f6ce13ddb5235
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.4.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TRPM6 CDCA2 ATP11B MED12L KIF14 IQGAP3 DOP1B

4.27e-071701217cf22a843ae2d9cd6693507fed2b7c6a45abea10e
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-secretory_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTK DDIAS FANCB USP51 EFR3B PLS3 IQGAP3

6.51e-071811217b203b616584cdbd0bbb0e382b2916d0bd49d3526
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-Reg4/cKit+_deep_crypt_secretory_cells_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTK DDIAS FANCB USP51 EFR3B PLS3 IQGAP3

6.51e-071811217c748c16fd20d1949d33ff6290dc9d9016c4dc86c
ToppCellBronchial-NucSeq-Immune_Lymphocytic-B-B_plasma-B_plasmablast|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TTK THAP9 CDCA2 DDIAS KIF14 IQGAP3 CREB3L2

1.07e-061951217a045fb8a377e54fb57fef1181d4c3fc15d627ef6
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 KIF1A CHRNE EGF UNC13C ADGRL2

2.34e-0614012165e81fa3a19d23f0e9cae3878431ca1f78dff7238
ToppCell3'_v3-blood-Lymphocytic_Invariant-Inducer-like-ILC3|blood / Manually curated celltypes from each tissue

SHANK1 THAP9 KCTD6 CCDC62 MED12L WDR72

4.53e-061571216eb2520c237543ea4869d4386afc0457b111f6193
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CDHR1 TTK CDCA2 KIF14 IQGAP3 NCKAP1L

7.39e-06171121655c7bf7211587fa08df13c0a4ff5b78a85d5439e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TTK CDCA2 FANCB KIF14 UNC13C IQGAP3

8.43e-061751216876cea684faf42ff3eb4623ad6d7a1fb1276ee02
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TTK CDCA2 FANCB MED12L KIF14 IQGAP3

9.90e-061801216401df9cddcbca1eb8f0d2687bcacd98e95dc1493
ToppCell343B-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CDCA2 DDIAS IGF2BP1 SOHLH2 MED12L IQGAP3

1.12e-0518412166b2449ac65a2322aa0479fba0d89828f243aabbe
ToppCell343B-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CDCA2 DDIAS IGF2BP1 SOHLH2 MED12L IQGAP3

1.12e-051841216e90622b82fa7f16a1faaf7a4724c958f2d83341d
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ACADSB VEPH1 TMEM132D EFR3B UNC13C CADPS2

1.12e-051841216102105ae1a5ef6d42a43f6d9b00f12ed0690ddb7
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TTK CDCA2 EFR3B KIF14 UNC13C IQGAP3

1.23e-051871216057569c9437219ecc396aa6e673b1178a2273837
ToppCellPBMC-Mild-cDC_12|Mild / Compartment, Disease Groups and Clusters

HIP1R TTK CDCA2 IQGAP3 KPNB1 WDR72

1.31e-051891216946c95d2ecc36b241f58e8c4ad6455fe47c762fa
ToppCellASK454-Epithelial-Secretory|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

PNPLA4 SLC1A5 STK3 NF1 USP51 DOP1B

1.39e-051911216c63c781e7e93265e591cf494cb4ce8ed797c24fb
ToppCellPCW_07-8.5-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

HIP1R TTK CDCA2 KIF14 IQGAP3 WDR72

1.43e-05192121625378b5e4b0cea8415ff125783511fc25a56fc00
ToppCellPCW_13-14-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

HIP1R TTK CDCA2 KIF14 IQGAP3 WDR72

1.51e-051941216c197e4acbff42a9f0410b6801c2bfcf6160aefc1
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

TTK CDCA2 DDIAS FANCB KIF14 IQGAP3

1.65e-05197121684ed777cdba569200a3ef1654d8a12f17fcfb7f1
ToppCellPCW_13-14-Endothelial-Endothelial_cycling-endo_proliferating2_(14)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

PDE4B TTK CDCA2 KIF14 RXFP1 IQGAP3

1.65e-0519712168e655db7c6f04d49927a1f0a75178e5955b4af08
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_neuro-secretory-Ionocyte_n_Brush|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

KIF1A BPIFA2 POPDC3 UNC13C SLC4A11 WDR72

1.65e-0519712168f009a15f154b3bb184b489da4722b7c27de7e11
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma|TCGA-Breast / Sample_Type by Project: Shred V9

COPG1 TTK CDCA2 DDIAS KIF14 IQGAP3

1.70e-051981216880f9817f5145f10f29fc05c5866090433532fe2
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_neuro-secretory|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

KIF1A BPIFA2 NRXN1 POPDC3 UNC13C WDR72

1.70e-0519812162591e08e3fbee86ac40f11becd8147d6d39fded6
ToppCellLPS_only-Hematopoietic_Erythro-Megakary|LPS_only / Treatment groups by lineage, cell group, cell type

SLC1A5 CDCA2 ATP11B GYPA MED12L KIF14

1.80e-052001216ce8281c9556a1f64f8ca8a029110077d4ef5b35e
ToppCellLPS_only-Hematopoietic_Erythro-Megakary-Erythro-Mega-Erythroid|LPS_only / Treatment groups by lineage, cell group, cell type

SLC1A5 CDCA2 ATP11B GYPA MED12L KIF14

1.80e-05200121683c4181c083b364f0d3a89ae7a0504781fa9fa9f
ToppCellLPS_only-Hematopoietic_Erythro-Megakary-Erythro-Mega|LPS_only / Treatment groups by lineage, cell group, cell type

SLC1A5 CDCA2 ATP11B GYPA MED12L KIF14

1.80e-052001216f15baf287ec467664c23faa53fdea45257f7b9d0
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Airway|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PWP2 EFR3B KIF14 KDF1 WDR72

2.26e-051241215a7b7d8b14d1218194da8fcf69b4780b6e9469332
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P5-P5_1-Sox4-POLYDENDROCYTE_(Neurogenesis.Sox4.Cdc20)|Hippocampus / BrainAtlas - Mouse McCarroll V32

TTK CDCA2 DDIAS KIF14 IQGAP3

2.94e-051311215f9fb8d74ca720b81fd5910cc975510359a8ef751
ToppCellLPS-antiTNF-Unknown-Endothelial-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHANK1 TTK CDCA2 KIF14 IQGAP3

3.05e-05132121502491930097b75aaeedab9e8200711b0dc610944
ToppCellLPS_only-Endothelial-Endothelial-FOXM1|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TEX15 TTK CDCA2 KIF14 IQGAP3

3.28e-0513412154d8f7ddad02fe76a614771e115ebb8e04623ba85
ToppCellControl-B_memory-6|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

PTCH1 NRXN1 ADGRL2 SLC4A11 WDR72

3.52e-05136121594f23bef50c0beb54ed39b1a4b340f7aec4e75cd
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P5-P5_1|Hippocampus / BrainAtlas - Mouse McCarroll V32

RADX TTK CDCA2 KIF14 IQGAP3

5.26e-051481215b9d3421c2eb8e748e9508c1cbd1cb4f96e23db5a
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P5-P5_1-Sox4|Hippocampus / BrainAtlas - Mouse McCarroll V32

RADX TTK CDCA2 KIF14 IQGAP3

5.26e-0514812152a7671dc27afbdf6a92d976c5f2b728bd18dd609
ToppCellPosterior_cortex-Macroglia-POLYDENDROCYTE-P4-Tnr-Polydendrocyte.Tnr.Dlx1_(Dlx1)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

RADX VEPH1 TTK CDCA2 KIF14

6.16e-051531215d7635f3d4831c02a94f53afc674847d5b51453be
ToppCellPosterior_cortex-Macroglia-POLYDENDROCYTE-P4-Tnr|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

RADX VEPH1 TTK CDCA2 KIF14

6.16e-05153121554a941950bbb848077c7bd5726da9e4b3244bd38
ToppCellPosterior_cortex-Macroglia-POLYDENDROCYTE-P4|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

RADX VEPH1 TTK CDCA2 KIF14

6.16e-05153121569a8550418ba0fc908a84b3b85761abb6e8ca4c0
ToppCellPosterior_cortex-Macroglia-POLYDENDROCYTE-P4-Tnr-Polydendrocyte.Tnr.Dlx1_(Dlx1)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

RADX VEPH1 TTK CDCA2 KIF14

6.16e-051531215e50d20f9e553b8c3e10e187770d8abe1a43d109e
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P5-P5_1|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

TTK CDCA2 DDIAS KIF14 IQGAP3

7.84e-0516112150dd1401b4c990d49fccb702a9f9867590a58e203
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P5-P5_1-Mitotic.MkI67_(Mitotic.MkI67)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

TTK CDCA2 DDIAS KIF14 IQGAP3

7.84e-051611215b6a31c033edc74f23a20aab1f18e80cc83ffee4c
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P5|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

TTK CDCA2 DDIAS KIF14 IQGAP3

7.84e-051611215efb811dda4d73107983a5f68302bdcf4f408d5b4
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P5-P5_1-Mitotic.MkI67_(Mitotic.MkI67)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

TTK CDCA2 DDIAS KIF14 IQGAP3

7.84e-05161121528d5dbd20c9f8e0069f172d552997a044790e1a7
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-hematologic-erythrocytic-erythrocyte|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SANBR TTK GYPA CCDC62 KIF14

8.08e-05162121525a11e4c6304324310b33a33331ebc812d045d4a
ToppCell15-Distal-Immune-Immune|Distal / Age, Tissue, Lineage and Cell class

BEND2 EGF MED12L POPDC3 NCKAP1L

8.08e-051621215e190c496ed1e206b86566edfee23c99a99fe90d0
ToppCellLPS-antiTNF-Endothelial-Endothelial-FOXM1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TTK CDCA2 DDIAS KIF14 IQGAP3

8.31e-0516312155285318c52aa31c9b22dc2ffff078e32e408604d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TTK CDCA2 DDIAS KIF14 IQGAP3

8.31e-0516312153f434015c0cbefb31eeda133c34f75384c5f7e22
ToppCellLPS-antiTNF-Epithelial_airway-Mes-Epi-like|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TTK CDCA2 NRXN1 KIF14 IQGAP3

8.56e-0516412154307b002fb41ddfc7ab8a6bca66a60942c250052
ToppCellLPS-antiTNF-Epithelial_airway-Mes-Epi-like-Airway|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TTK CDCA2 NRXN1 KIF14 IQGAP3

8.56e-0516412151d84aa5b925f502ee9c5fa39714490f613a58028
ToppCellDividing_Macrophages-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

MYO7B TTK CDCA2 KIF14 IQGAP3

9.06e-051661215c503036f3c19ef186e1e62c9643c49dea3827f51
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KIF1A TTK CDCA2 KIF14 IQGAP3

9.32e-05167121550c29ea660bf07b890e4ac1a1985d0761d863dee
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PDE4B DDIAS AGAP2 CREB3L2 NCKAP1L

9.32e-0516712150130743084dbcb20e10f96715d30961122150cbf
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B-Plasma_Cell-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PDE4B DDIAS AGAP2 CREB3L2 NCKAP1L

9.32e-0516712157bcae3797d3a0811e7f39885afdfd29ec517f11b
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B-Plasma_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PDE4B DDIAS AGAP2 CREB3L2 NCKAP1L

9.32e-051671215c6f0209a1ad797631fdfa3efab6db6b1d3e8e315
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KIF1A TTK CDCA2 KIF14 IQGAP3

9.59e-051681215d35944fd9fea9934ce1e76b2b35d48e2300cca61
ToppCellDividing_Macrophages-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

TTK CDCA2 FANCB KIF14 IQGAP3

9.86e-051691215eb0c993ef2eea73bc4881182520922ce9ae9368f
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-FOXM1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TTK CDCA2 DDIAS KIF14 IQGAP3

9.86e-051691215e0607af8ae8609d43e26ff2a2cab92650bfcd5b7
ToppCell367C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

PIGN TTK CDCA2 DDIAS KIF14

1.04e-041711215e3cab55f39879e2bd3e8bda91802181075839bc4
ToppCell367C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

PIGN TTK CDCA2 DDIAS KIF14

1.04e-04171121552fdc2a4ec36fb91583b1215362548ceb6740ae1
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PDE4B EGF UNC13C RXFP1 CADPS2

1.10e-041731215ee972d9cc68755926512fd3bbe1267098c67cd94
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CDCA2 FANCB KIF14 IQGAP3 NCKAP1L

1.13e-0417412157b318796728001c17b4043d2b033330c7be40c78
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TTK CDCA2 DDIAS KIF14 IQGAP3

1.13e-041741215dbb4e1a6c3319ce40f81bfd2d1745a88a2cc412e
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c11-MKI67-FOS|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

TTK CDCA2 FANCB KIF14 IQGAP3

1.29e-041791215ac987c9425a1b4106d1b8779a2c5461383eae2ae
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TTK CDCA2 DDIAS KIF14 IQGAP3

1.29e-04179121554191c00b29f53b520cd3243b5791daa4a2c72d7
ToppCellcontrol-Lymphoid-NKT-proliferating|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

TTK CDCA2 FANCB KIF14 IQGAP3

1.32e-041801215535535a67b3f3320bad2f98b1bc98a7b0ee77840
ToppCellLPS-IL1RA-Endothelial-Endothelial-FOXM1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TTK CDCA2 DDIAS KIF14 IQGAP3

1.32e-041801215334e2b1f6eb7d4ece20b1c7b02107863f913237f
ToppCellIIH-cycling-|IIH / Condition, Cell_class and T cell subcluster

TTK CDCA2 KIF14 RXFP1 IQGAP3

1.36e-0418112157f4fed9e296bc22cb5a1e6c8e3c4b641e97c3078
ToppCellIIH-cycling|IIH / Condition, Cell_class and T cell subcluster

TTK CDCA2 KIF14 RXFP1 IQGAP3

1.36e-041811215ec3e782ce93dcfe1a54fb7284e4e39063614b0e2
ToppCellHealthy_Control-Lymphoid-T-|Healthy_Control / Condition, Lineage, Cell class and cell subclass

TTK CDCA2 SLC10A5 KIF14 IQGAP3

1.36e-041811215ac1ee313910c05b1b3cb497bae14565464919c21
ToppCell10x5'-bone_marrow-Hematopoietic_progenitors-Cycling_pre-Myeloid-1|bone_marrow / Manually curated celltypes from each tissue

CDCA2 RXFP2 KIF14 SCARA3 IQGAP3

1.36e-041811215ccd0ed30cea3fb41d34f28b3e8d80a94493bef3c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TTK CDCA2 KIF14 UNC13C IQGAP3

1.39e-041821215336cd05e46a741185ce3c59ee67a4b07fa6a5101
ToppCell3'_v3-blood-Hematopoietic_Erythro-Mega|blood / Manually curated celltypes from each tissue

VEPH1 BEND2 EGF MED12L PLS3

1.39e-0418212153100165c5ba8c3016f9a2f7a8e4ea136750823fe
ToppCellNS-control-d_0-4-Lymphoid-NKT-proliferating|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TTK CDCA2 FANCB KIF14 IQGAP3

1.39e-041821215f623c47e7806181d09f126066a952162ce49a306
ToppCellTCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-5|TCGA-Liver / Sample_Type by Project: Shred V9

TTK CDCA2 DDIAS FANCB KIF14

1.43e-041831215f604a8b62c7088fad8365dbf8d910fc980bd3ba8
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Epcam_____kidney_distal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM6 ACADSB MREG EGF CADPS2

1.43e-041831215f3728b1a51951c7349f77a3e4d2671ca3a8d2a44
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 EGF UNC13C CADPS2 ADGRL2

1.43e-0418312152e831a4d99c6f983793df71c0994124c943c6da9
ToppCellmild_COVID-19_(asymptomatic)-T/NK_proliferative|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

TTK CDCA2 FANCB KIF14 IQGAP3

1.43e-041831215df8568751205313d149939ea2683097e3652a60b
ToppCellDividing_Macrophages-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

TTK CDCA2 FANCB KIF14 IQGAP3

1.47e-041841215f15ce786d25c6546804a6d1efcc2ad645f2ef54e
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_B-GC_B_(I)|lymph-node_spleen / Manually curated celltypes from each tissue

TEX15 TTK CDCA2 DDIAS KIF14

1.47e-041841215057c6c2f570914fa4af84682589a86b61547d6c9
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-kidney_distal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM6 ACADSB MREG EGF CADPS2

1.47e-0418412158939b6d795992775df0ff58ed1ec9d421a00bcc4
ToppCellControl-T_cells-Cycling_NK/T_cells|Control / group, cell type (main and fine annotations)

TTK CDCA2 FANCB KIF14 IQGAP3

1.51e-0418512159766216b41ee62bbac4caa25cb98ec5627a24075
ToppCellfacs-Skin-Telogen-3m-Epithelial-actively_dividing_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTK CDCA2 DDIAS KIF14 IQGAP3

1.54e-0418612159feef5936985e936b3d88f9d1bb012abb6468570
ToppCellCOVID-19-lung-Plasma_cells_PRDM1/BLIMP_hi|lung / Disease (COVID-19 only), tissue and cell type

ZYG11A CDCA2 DDIAS KIF14 CREB3L2

1.54e-04186121566676d9395172de5707e204826a1c9f73b448cca
ToppCellDividing_Macrophages-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

TTK CDCA2 FANCB KIF14 IQGAP3

1.54e-0418612150067eb78d4c7e32b9563550d9fcaf13445ee6a48
ToppCell343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

RALGAPA1 SHLD2 COPG1 COMMD1 PPP6R3

1.54e-041861215bbb8edea8d8bdc1a469faec1563e40b1f62d7f3d
ToppCellfacs-Skin-Telogen-3m-Epithelial-keratinocyte_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTK CDCA2 DDIAS KIF14 IQGAP3

1.54e-04186121589f5b06bc56674af304912d481ac697c7c870904
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TTK CDCA2 FANCB KIF14 IQGAP3

1.58e-0418712159351fa87b69a951af85b10bf91fe9b1cce8c0517
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TTK CDCA2 DDIAS KIF14 IQGAP3

1.58e-04187121573931a5ea73799095daff100b5f18853c57c74dc
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC168 TTK CDCA2 DDIAS KIF14

1.62e-041881215319fbeca200ab998daf49fcaee0bfdb57bf7ee4b
ToppCell3'_v3-lymph-node_spleen-Myeloid_Dendritic-Cycling_Dendritic|lymph-node_spleen / Manually curated celltypes from each tissue

TEX15 TTK CDCA2 KIF14 IQGAP3

1.62e-041881215723348a1836a074e068320cb736ce6a953e0038f
ToppCelldroplet-Kidney-nan-3m-Epithelial-kidney_distal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM6 ACADSB MREG EGF CADPS2

1.66e-041891215e127e3be626bc513e151d41812f0b7adb89d5da6
ToppCellfacs-Skin-Anagen-3m-Epithelial-actively_dividing_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTK CDCA2 DDIAS KIF14 IQGAP3

1.66e-041891215bfa3ed1360991a3e32fad133017c413f8adc1eba
ToppCellPBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil-Neu_2|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

TRPM6 SYNE1 KIF1B VEPH1 MED12L

1.66e-0418912153b35022c0619df6db234613aa53a076899ca9562
ToppCellPBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil-Neu_2|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TRPM6 SYNE1 KIF1B VEPH1 MED12L

1.66e-041891215358ff514f1c8aa46067208ddf1b68396d789c130
ToppCellfacs-Skin-Anagen-3m-Epithelial-keratinocyte_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTK CDCA2 DDIAS KIF14 IQGAP3

1.66e-04189121596f10c63656e446b4bb712f012e91ae986f8c2d0
ToppCelldroplet-Kidney-nan-3m-Epithelial-Epcam_____kidney_distal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM6 ACADSB MREG EGF CADPS2

1.66e-041891215ff637ae0afdb1fdc67451be7e1e4fe575fbcfff4
ToppCellInt-URO-Lymphocyte-T_NK-T_NK_proliferative|Int-URO / Disease, Lineage and Cell Type

ZYG11A CDHR1 TTK CDCA2 IQGAP3

1.70e-041901215005967c540418b85311308072a07c684f4296aef
ToppCellPCW_10-12-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

TTK CDCA2 KIF14 IQGAP3 WDR72

1.75e-04191121539220f4a345e328f7fa4fd462a0abeea821b3e02
ToppCell343B-Lymphocytic-ILC-ILC-1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

DYM ACADSB PNPLA4 HEATR5A ATP11B

1.79e-041921215445985fe1bcd33e4f0a1704b27988fbfc9334538
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

RALGAPA1 KIF1B HEATR5A ATP11B CPLANE1

1.83e-041931215abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCelldroplet-Heart-nan-18m-Hematologic-erythrocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C17orf67 VEPH1 GYPA RXFP1

1.86e-041041214060f0baca239ab89c18be40c1aa31931f4791b62
DiseaseAutistic Disorder

SHANK1 PDE4B KIF1A ACADSB NF1 EGF NRXN1 CADPS2 ZNF292

1.28e-062611209C0004352
Diseasebody surface area

RALGAPA1 C17orf67 PDE4B DYM DIS3L2 KIF1A COPG1 PTCH1 LUZP1 BAIAP2 CADPS2 PPP6R3

1.28e-0564312012EFO_0022196
Diseasecongenital myasthenic syndrome (implicated_via_orthology)

CHRNB3 CHRND CHRNE

3.53e-05161203DOID:3635 (implicated_via_orthology)
DiseaseMyasthenic Syndrome, Congenital, Fast-Channel

CHRND CHRNE

4.91e-0531202C1837122
Diseasesynucleinopathy (biomarker_via_orthology)

KIF1A KIF1B

9.79e-0541202DOID:0050890 (biomarker_via_orthology)
DiseaseMYASTHENIC SYNDROME, CONGENITAL, 1A, SLOW-CHANNEL

CHRND CHRNE

9.79e-0541202C4084823
DiseaseNeurofibromatosis 3

NF1 SMARCB1

1.63e-0451202C0917817
DiseaseC-C motif chemokine 14 measurement

OR10J5 OR10J4 CCL14

1.79e-04271203EFO_0008042
DiseaseAbnormal muscle tone

MAPK8IP3 ZNF292

2.43e-0461202C0852413
Diseaseanxiety disorder

PDE4B TMEM132D MGAM2

2.46e-04301203EFO_0006788
Diseasephotoreceptor cell layer thickness measurement

RALGAPA1 CDHR1 MREG KIF14 WDR72

3.56e-041481205EFO_0803370
DiseaseIntellectual Disability

RALGAPA1 SYNE1 PGM3 MAPK8IP3 NF1 NRXN1 MED12L ZNF292

4.99e-044471208C3714756
DiseaseAbnormality of nervous system morphology

MAPK8IP3 ZNF292

7.23e-04101202C4022810
DiseaseBasal cell carcinoma

ERCC3 PTCH1

8.81e-04111202C0007117
Diseasenervous system disease (implicated_via_orthology)

KIF1A KIF1B

1.05e-03121202DOID:863 (implicated_via_orthology)
Diseasecleft lip

C17orf67 SYNE1 MUC16 CCDC168 TMEM132D MGAM2

1.10e-032841206EFO_0003959
Diseasehepcidin:transferrin saturation ratio

MUC16 KCTD6

1.66e-03151202EFO_0007902
Diseasesexual dimorphism measurement

DOC2A RALGAPA1 C17orf67 DYM DIS3L2 KIF1A PTCH1 NF1 GYPA EFR3B PPP6R3 AGAP2

1.86e-03110612012EFO_0021796
DiseasePheochromocytoma, Extra-Adrenal

KIF1B NF1

1.90e-03161202C1257877
Diseasekidney volume

PTCH1 GYPA

2.40e-03181202EFO_0600044
Diseasechemerin measurement

PTCH1 UNC13C

2.68e-03191202EFO_0004573
DiseasePheochromocytoma

KIF1B NF1

2.68e-03191202C0031511
Diseaseosteoarthritis, hip, osteoarthritis, knee, total joint arthroplasty

C17orf67 PTCH1

3.27e-03211202EFO_0004616, EFO_0010726, EFO_1000786
Diseasecoronary artery disease

KIF1A UBE3B MAPK8IP3 STK3 IGF2BP1 COMMD1 NRXN1 TMEM132D RPRD2 ADGRL2 KDF1 WDR72

3.47e-03119412012EFO_0001645
DiseaseHereditary Paraganglioma-Pheochromocytoma Syndrome

KIF1B NF1

3.92e-03231202C1708353

Protein segments in the cluster

PeptideGeneStartEntry
EGEKLSLSTSVLVSL

CHRNB3

261

Q05901
SNLISLKEVEETLTT

CHRND

61

Q07001
ATILTSLFTDSLVKE

BZW2

166

Q9Y6E2
FVKIITILVTATASS

SLC1A5

411

Q15758
IATLISSFLKELLVE

PGM3

301

O95394
IISSTALFLAAKVEE

CCNT2

81

O60583
FSTTALLKIDITDAE

CDHR1

666

Q96JP9
TDVTSNLLTVTIKEF

CBX6

371

O95503
SVITLSSIFTKDLVE

CCDC62

391

Q6P9F0
ASFLSTVLVIEELAK

ACADSB

116

P45954
TITSSAELFKTIIST

ADGRL2

406

O95490
RTTTYLISLTLVKLE

AGAP2

11

Q99490
ELSTSLFFAVLVKES

DIS3L2

751

Q8IYB7
EATLSELKTVLKSFL

ATP5PO

151

P48047
EDTVTISLKVTLTNL

CHRNE

46

Q04844
ESLSVILKSVLTAFL

RFT1

156

Q96AA3
FLIASKELELITLTV

NCSTN

661

Q92542
SSIKVESLLTAISEV

RADX

521

Q6NSI4
LLVVTETSDTTLTSK

MUC16

2596

Q8WXI7
TLTSKILVTDTILFS

MUC16

2606

Q8WXI7
SLLVSELEDTTEKTA

KIF14

101

Q15058
ELSVVEAELLLKSSS

MED12L

856

Q86YW9
LTSTLTTSKVVIIDA

MAPK8IP3

776

Q9UPT6
LLLLVLEETSDTSFT

MGAM2

26

Q2M2H8
KTLSFSVFEIILITS

IL31RA

511

Q8NI17
TETKITISSLQDLTL

IGF2BP1

306

Q9NZI8
LSTEKVSKISLVDLA

KIF1B

236

O60333
SEIVKTVNLLITSLS

DOP1B

426

Q9Y3R5
RILFSKEILISSSVD

BEND2

511

Q8NDZ0
DFALTIKSISVSLRE

DDX60

1671

Q8IY21
ISDFLTLHSIIISLV

FEM1B

546

Q9UK73
DKTISSSLAVVDLID

PLS3

546

P13797
DLLKTFRISSDTFIT

PDE4B

376

Q07343
VSTFSSREDLIKVLL

PNPLA4

126

P41247
FSTISTLSDISVLKL

EFR3B

491

Q9Y2G0
ALSSSSKDLETIVTL

DDIAS

541

Q8IXT1
ILLLEIKSITDTFSS

VEPH1

326

Q14D04
DSVEKLLVETSDLST

NCKAP1L

526

P55160
TDIKVTLSIFELASA

NCKAP1L

951

P55160
FLLITIALGTKTESS

CCL14

11

Q16627
IQSSSDEITLSFKTL

NRXN1

301

Q9ULB1
TLVSFLSERKTISLS

OR13C5

81

Q8NGS8
TLVSFLSERKTISLS

OR13C2

81

Q8NGS9
KLEEIADLVTSVLSS

PPP4R3B

141

Q5MIZ7
KIASDAASILIFTLE

MROH9

271

Q5TGP6
TDKFLLAITSSVDQI

IQGAP3

1126

Q86VI3
TDTHVKELALFSLSI

OR10T2

191

Q8NGX3
FTLEKELVTLSSLSS

FANCB

761

Q8NB91
VLIDLLSETKTISFS

OR4D9

81

Q8NGE8
TDFVLASLVIVSSLL

OR6S1

201

Q8NH40
VELVTVKSFDTSLIR

ATP6AP2

261

O75787
ISAVTVELSKETLDT

COMMD9

166

Q9P000
LLVTTSTSLQKEIVE

HIP1R

836

O75146
VSLLTAITVFILSTS

HEATR5A

1826

Q86XA9
LKASLDLLTAVTIET

BPIFA2

146

Q96DR5
IELSTLATKTLEVTV

DOC2A

326

Q14183
LASKTISISEEVRFL

CPLANE1

2756

Q9H799
SSSELKLLEEATISV

DYM

46

Q7RTS9
LETSEKITAVSLDVL

EGF

196

P01133
IDLKTNLTTVLSEFS

FRMPD3

426

Q5JV73
LDKFLASVSTVLTSK

HBA1;

126

P69905
VLVLSLTLLTVFSET

C17orf67

6

Q0P5P2
IFVLLLSEIVSISAS

GYPA

6

P02724
LSKSDVVLSFTLEIV

CADPS2

356

Q86UW7
SELEKLKSLTLSFVS

LUZP1

181

Q86V48
SSFELIVQKLLETTD

KPNB1

501

Q14974
AVETSVDLSEISSKL

CDCA2

236

Q69YH5
ILKTLSEVEESISTL

COMMD1

171

Q8N668
TFEEVVELSSTRKLS

KCTD6

116

Q8NC69
EETFTLSTIKTLEEA

COPG1

786

Q9Y678
ATELITETFTSKSAI

ERCC3

206

P19447
TFLEKRITSSLTSEE

CCDC168

106

Q8NDH2
VDLAKISSILSSLTS

RPRD2

451

Q5VT52
VFRKVDSLSEDISLT

SCARA3

76

Q6AZY7
FRTIALSSEVVTLEK

POPDC3

126

Q9HBV1
FIISNETSLEKSVLL

CREB3L2

476

Q70SY1
ITTEKVSKISLVDLA

KIF1A

236

Q12756
FLSHLSTLEILVTTI

OR9A2

61

Q8NGT5
ADTTIKEFITLLISL

OR10J4

191

P0C629
SIEKDLVLSVTYTII

OR10J5

266

Q8NHC4
KRSTEEIIALFISIT

SLC4A11

471

Q8NBS3
SSSFKALVTLLSEVE

SYNE1

1211

Q8NF91
IKLFLSELQTTSEIS

SYNE1

1781

Q8NF91
LSDTILAEKTITVLD

TMEM132D

646

Q14C87
LYLSSLKETLSIVAV

HPS3

956

Q969F9
ADSLLSVTKLSTISD

MREG

121

Q8N565
VKEVLSKLSTLVETT

PPP5C

216

P53041
TQKVLSFTTTTLDDI

PTCH1

416

Q13635
TLDDILKSFSDVSVI

PTCH1

426

Q13635
VSDLKISTDTEFLSI

SHLD2

231

Q86V20
TEVSVLLLTYLTLEK

RXFP2

506

Q8WXD0
TSVTLLKASEVEEIL

SMARCB1

86

Q12824
LTTSSEKSEIHLFLQ

SKIV2L

591

Q15477
TVFLEKTSKISDLIS

KDF1

266

Q8NAX2
VETLATYIKSSLLDI

SANBR

81

Q6NSI8
KTEILFFTKTEETIL

SLC10A5

31

Q5PT55
ILTKVSDILHSLFST

RANBP6

846

O60518
SALATVKASIISELS

SHANK1

1861

Q9Y566
STLLSFKEGDLITLL

BAIAP2

391

Q9UQB8
ILISEAVISTILKYT

ATP11B

296

Q9Y2G3
SEELLKLATSISETL

UBA6

351

A0AVT1
SILVLASTITILKDF

SLC30A8

256

Q8IWU4
VTLILADLIFTDSKL

TPTE

106

P56180
EKILRLLTSTSTDVS

USP51

306

Q70EK9
KTLIEDEIATILKST

STK3

116

Q13188
FILSQEDITTIFKTL

VPS13A

1321

Q96RL7
ALTVDTLKVLSAVDT

TRPM6

1216

Q9BX84
FTDVKELIIKTVLSS

RALGAPA1

1266

Q6GYQ0
DLKSTVDLLTSITFF

UNC13C

1511

Q8NB66
VLIEAKTIFVTLSDT

THAP9

546

Q9H5L6
TKETLALTSDALAVT

PWP2

536

Q15269
LQTSFVTLDEAIKIT

ATP6V1D

151

Q9Y5K8
ELFITKLINEDSTSV

ZNF292

2486

O60281
VDASLTIDTAKLFLS

WDR72

786

Q3MJ13
LLDVVLDSFIKTSAT

NF1

2006

P21359
TFALTSLETVTEALL

NF1

2196

P21359
TEVSVLLLTFLTLEK

RXFP1

496

Q9HBX9
SSKSLFLIVLVISDI

PIGN

856

O95427
LTDSKLLLQSSLTET

TOPAZ1

541

Q8N9V7
EQISFKLEELVTISS

UBE3B

551

Q7Z3V4
SELIITDSITLKNKT

TTK

346

P33981
LLDVEKVSLSDVSTF

TARBP1

541

Q13395
IVELSSSDSSLLLKD

TEX15

1426

Q9BXT5
VTITISDTKEAAALL

SOHLH2

46

Q9NX45
TLSLTVDAKTETAVF

PPP6R3

801

Q5H9R7
VLETFSESAIQSKVL

ZYG11A

566

Q6WRX3
DVLSTDILTLVYSSK

MYO7B

571

Q6PIF6
LSTLATIKDDTIATI

NECTIN3

391

Q9NQS3