Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLC25A24 SLC6A9 ATP13A4 SLC8A2 TMC2 P2RX1 SLC16A9 BEST2 KCNV2 TRPM2 KCNJ15 KCNK10 KCNK2 ABCD4 LRP6 LRP5 GRIA2 CACNG5 GJB7 NDUFB5 CNGA1 CNGA2 GABRR3

2.49e-0911809223GO:0022857
GeneOntologyMolecularFunctiongated channel activity

TMC2 P2RX1 BEST2 KCNV2 TRPM2 KCNJ15 KCNK10 KCNK2 GRIA2 CACNG5 CNGA1 CNGA2 GABRR3

4.33e-093349213GO:0022836
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

SLC25A24 SLC6A9 ATP13A4 SLC8A2 TMC2 P2RX1 BEST2 KCNV2 TRPM2 KCNJ15 KCNK10 KCNK2 GRIA2 CACNG5 NDUFB5 CNGA1 CNGA2 GABRR3

9.22e-097589218GO:0015318
GeneOntologyMolecularFunctiontransporter activity

SLC25A24 SLC6A9 ATP13A4 SLC8A2 TMC2 P2RX1 SLC16A9 BEST2 KCNV2 TRPM2 KCNJ15 KCNK10 KCNK2 ABCD4 LRP6 LRP5 GRIA2 CACNG5 GJB7 NDUFB5 CNGA1 CNGA2 GABRR3

1.32e-0812899223GO:0005215
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SLC6A9 ATP13A4 SLC8A2 TMC2 P2RX1 KCNV2 TRPM2 KCNJ15 KCNK10 KCNK2 GRIA2 CACNG5 CNGA1 CNGA2

2.73e-084659214GO:0046873
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

SLC6A9 ATP13A4 SLC8A2 TMC2 P2RX1 BEST2 KCNV2 TRPM2 KCNJ15 KCNK10 KCNK2 GRIA2 CACNG5 NDUFB5 CNGA1 CNGA2

5.62e-086649216GO:0008324
GeneOntologyMolecularFunctionmonoatomic cation channel activity

TMC2 P2RX1 BEST2 KCNV2 TRPM2 KCNJ15 KCNK10 KCNK2 GRIA2 CACNG5 CNGA1 CNGA2

5.77e-083439212GO:0005261
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

SLC6A9 ATP13A4 SLC8A2 TMC2 P2RX1 BEST2 KCNV2 TRPM2 KCNJ15 KCNK10 KCNK2 GRIA2 CACNG5 NDUFB5 CNGA1 CNGA2 GABRR3

1.11e-077939217GO:0015075
GeneOntologyMolecularFunctionchannel activity

TMC2 P2RX1 BEST2 KCNV2 TRPM2 KCNJ15 KCNK10 KCNK2 GRIA2 CACNG5 GJB7 CNGA1 CNGA2 GABRR3

1.22e-075259214GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

TMC2 P2RX1 BEST2 KCNV2 TRPM2 KCNJ15 KCNK10 KCNK2 GRIA2 CACNG5 GJB7 CNGA1 CNGA2 GABRR3

1.25e-075269214GO:0022803
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

SLC6A9 ATP13A4 SLC8A2 TMC2 P2RX1 KCNV2 TRPM2 KCNJ15 KCNK10 KCNK2 GRIA2 CACNG5 NDUFB5 CNGA1 CNGA2

1.69e-076279215GO:0022890
GeneOntologyMolecularFunctionmonoatomic ion channel activity

TMC2 P2RX1 BEST2 KCNV2 TRPM2 KCNJ15 KCNK10 KCNK2 GRIA2 CACNG5 CNGA1 CNGA2 GABRR3

1.81e-074599213GO:0005216
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

ATP13A4 SLC8A2 TMC2 P2RX1 TRPM2 CACNG5 CNGA1 CNGA2

4.83e-07151928GO:0015085
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity

P2RX1 BEST2 TRPM2 KCNJ15 GRIA2 CNGA1 CNGA2 GABRR3

3.06e-06193928GO:0015276
GeneOntologyMolecularFunctionligand-gated channel activity

P2RX1 BEST2 TRPM2 KCNJ15 GRIA2 CNGA1 CNGA2 GABRR3

3.57e-06197928GO:0022834
GeneOntologyMolecularFunctionligand-gated monoatomic cation channel activity

P2RX1 BEST2 TRPM2 KCNJ15 GRIA2 CNGA1 CNGA2

3.82e-06140927GO:0099094
GeneOntologyMolecularFunctionvoltage-gated monoatomic cation channel activity

TMC2 KCNV2 KCNJ15 KCNK10 KCNK2 CACNG5 CNGA2

6.57e-06152927GO:0022843
GeneOntologyMolecularFunctionintracellularly ligand-gated monoatomic ion channel activity

BEST2 TRPM2 CNGA1 CNGA2

1.56e-0533924GO:0005217
GeneOntologyMolecularFunctionspermidine binding

SAT1 SATL1

2.10e-052922GO:0019809
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity

TMC2 KCNV2 KCNJ15 KCNK10 KCNK2 CACNG5 CNGA2

2.12e-05182927GO:0005244
GeneOntologyMolecularFunctionvoltage-gated channel activity

TMC2 KCNV2 KCNJ15 KCNK10 KCNK2 CACNG5 CNGA2

2.28e-05184927GO:0022832
GeneOntologyMolecularFunctionpotassium channel activity

KCNV2 KCNJ15 KCNK10 KCNK2 GRIA2 CNGA2

2.80e-05128926GO:0005267
GeneOntologyMolecularFunctioncalcium channel activity

TMC2 P2RX1 TRPM2 CACNG5 CNGA1 CNGA2

2.93e-05129926GO:0005262
GeneOntologyMolecularFunctionpolyamine binding

SAT1 SATL1

6.28e-053922GO:0019808
GeneOntologyMolecularFunctionvoltage-gated potassium channel activity

KCNV2 KCNJ15 KCNK10 KCNK2 CNGA2

1.09e-04102925GO:0005249
GeneOntologyMolecularFunctionpotassium ion transmembrane transporter activity

KCNV2 KCNJ15 KCNK10 KCNK2 GRIA2 CNGA2

1.23e-04167926GO:0015079
GeneOntologyMolecularFunction1-phosphatidylinositol 4-kinase activity

PI4K2B PI4K2A

1.25e-044922GO:0004430
GeneOntologyMolecularFunctiondiamine N-acetyltransferase activity

SAT1 SATL1

1.25e-044922GO:0004145
GeneOntologyMolecularFunctionintracellularly cGMP-activated cation channel activity

CNGA1 CNGA2

4.34e-047922GO:0005223
GeneOntologyMolecularFunctionclathrin light chain binding

CLTCL1 CLTC

4.34e-047922GO:0032051
GeneOntologyMolecularFunctionmannosyl-oligosaccharide 1,2-alpha-mannosidase activity

MAN1A2 MAN1A1

5.77e-048922GO:0004571
GeneOntologyMolecularFunctionintracellularly cAMP-activated cation channel activity

CNGA1 CNGA2

9.22e-0410922GO:0005222
GeneOntologyMolecularFunctionmannosyl-oligosaccharide mannosidase activity

MAN1A2 MAN1A1

9.22e-0410922GO:0015924
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC6A9 SLC8A2 TRPM2 GRIA2 CNGA1

1.17e-03171925GO:0015081
GeneOntologyMolecularFunctiontoxin transmembrane transporter activity

LRP6 LRP5

1.34e-0312922GO:0019534
GeneOntologyMolecularFunctionintracellularly cyclic nucleotide-activated monoatomic cation channel activity

CNGA1 CNGA2

1.58e-0313922GO:0005221
GeneOntologyMolecularFunctioncyclic nucleotide-activated monoatomic ion channel activity

CNGA1 CNGA2

1.58e-0313922GO:0043855
GeneOntologyMolecularFunctionsodium channel activity

TRPM2 GRIA2 CNGA1

1.78e-0352923GO:0005272
GeneOntologyMolecularFunctionendodeoxyribonuclease activity, producing 5'-phosphomonoesters

DNA2 DNASE1L2

1.84e-0314922GO:0016888
GeneOntologyMolecularFunctionalpha-mannosidase activity

MAN1A2 MAN1A1

2.12e-0315922GO:0004559
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLC25A24 SLC6A9 SLC16A9 BEST2 ABCD4 GRIA2

2.35e-03293926GO:0008514
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor activity

LRP6 LRP1B

2.42e-0316922GO:0005041
GeneOntologyMolecularFunctionpotassium ion leak channel activity

KCNK10 KCNK2

2.42e-0316922GO:0022841
GeneOntologyMolecularFunctioncGMP binding

CNGA1 CNGA2

2.42e-0316922GO:0030553
GeneOntologyMolecularFunctionmannosidase activity

MAN1A2 MAN1A1

2.42e-0316922GO:0015923
GeneOntologyMolecularFunctionWnt receptor activity

LRP6 LRP5

2.73e-0317922GO:0042813
GeneOntologyMolecularFunctionnarrow pore channel activity

KCNK10 KCNK2

3.41e-0319922GO:0022842
GeneOntologyMolecularFunctionleak channel activity

KCNK10 KCNK2

3.41e-0319922GO:0022840
GeneOntologyMolecularFunctionDNA nuclease activity

POLE DNA2 DNASE1L2

3.66e-0367923GO:0004536
GeneOntologyMolecularFunctionlipoprotein particle receptor activity

LRP6 LRP1B

4.17e-0321922GO:0030228
GeneOntologyMolecularFunctionamine binding

SAT1 SATL1

4.17e-0321922GO:0043176
GeneOntologyMolecularFunctionextracellular ligand-gated monoatomic ion channel activity

P2RX1 GRIA2 GABRR3

5.41e-0377923GO:0005230
GeneOntologyMolecularFunctioncAMP binding

CNGA1 CNGA2

5.88e-0325922GO:0030552
GeneOntologyMolecularFunctionDNA-directed DNA polymerase activity

POLE DNTT

5.88e-0325922GO:0003887
GeneOntologyMolecularFunctionphosphatidylinositol kinase activity

PI4K2B PI4K2A

6.35e-0326922GO:0052742
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC25A24 SLC6A9 ATP13A4 SLC8A2 SLC16A9 ABCD4 NDUFB5

6.51e-03477927GO:0022804
GeneOntologyMolecularFunctionoutward rectifier potassium channel activity

KCNK10 KCNK2

6.84e-0327922GO:0015271
GeneOntologyMolecularFunctioncatalytic activity, acting on DNA

BPTF POLE DNA2 DNASE1L2 DNTT

7.29e-03262925GO:0140097
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

SLC6A9 ATP13A4 SLC8A2 TMC2 P2RX1 BEST2 KCNV2 TRPM2 KCNJ15 KCNK10 KCNK2 GRIA2 CACNG5 CNGA1 CNGA2 CRHR1

4.41e-069429316GO:0098655
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

SLC6A9 ATP13A4 SLC8A2 TMC2 P2RX1 BEST2 KCNV2 TRPM2 KCNJ15 KCNK10 KCNK2 GRIA2 CACNG5 CNGA1 CNGA2 CRHR1 GABRR3

8.92e-0611159317GO:0034220
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

SLC6A9 ATP13A4 SLC8A2 TMC2 P2RX1 BEST2 KCNV2 TRPM2 KCNJ15 KCNK10 KCNK2 CACNG5 CNGA1 CNGA2 CRHR1 GABRR3

1.15e-0510179316GO:0098660
GeneOntologyBiologicalProcessmonoatomic cation transport

SLC6A9 ATP13A4 SLC8A2 TMC2 P2RX1 BEST2 KCNV2 TRPM2 KCNJ15 CLTC KCNK10 KCNK2 GRIA2 CACNG5 CNGA1 CNGA2 CRHR1

1.44e-0511579317GO:0006812
GeneOntologyBiologicalProcessmonoatomic ion transport

SLC6A9 ATP13A4 SLC8A2 TMC2 P2RX1 BEST2 KCNV2 TRPM2 KCNJ15 CLTC KCNK10 KCNK2 GRIA2 CACNG5 CNGA1 CNGA2 CRHR1 GABRR3

3.62e-0513749318GO:0006811
GeneOntologyBiologicalProcessmetal ion transport

SLC6A9 ATP13A4 SLC8A2 TMC2 P2RX1 KCNV2 TRPM2 KCNJ15 CLTC KCNK10 KCNK2 CACNG5 CNGA1 CNGA2 CRHR1

3.89e-0510009315GO:0030001
GeneOntologyBiologicalProcesspolyamine acetylation

SAT1 SATL1

6.02e-053932GO:0032917
GeneOntologyBiologicalProcessspermidine acetylation

SAT1 SATL1

6.02e-053932GO:0032918
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

SLC6A9 ATP13A4 SLC8A2 TMC2 P2RX1 KCNV2 TRPM2 KCNJ15 KCNK10 KCNK2 CACNG5 CNGA1 CNGA2 CRHR1

6.37e-059229314GO:0098662
GeneOntologyBiologicalProcesscalcium ion transmembrane transport

ATP13A4 SLC8A2 TMC2 P2RX1 TRPM2 CACNG5 CNGA1 CNGA2 CRHR1

6.95e-05392939GO:0070588
GeneOntologyBiologicalProcesscell migration involved in gastrulation

GPC3 LRP6 LRP5

9.57e-0520933GO:0042074
GeneOntologyBiologicalProcessNorrin signaling pathway

LRP6 LRP5

1.99e-045932GO:0110135
GeneOntologyBiologicalProcessregulation of membrane potential

SLC8A2 P2RX1 BEST2 KCNV2 KCNK10 KCNK2 GRIA2 CNGA1 CNGA2 GABRR3

2.12e-045599310GO:0042391
GeneOntologyBiologicalProcessestablishment of blood-retinal barrier

LRP6 LRP5

2.98e-046932GO:1990963
GeneOntologyBiologicalProcessimport into cell

SLC6A9 SLC8A2 CLTCL1 P2RX1 GPC3 TRPM2 KCNJ15 CLTC LRP6 LRP5 GRIA2 CACNG5 LRP1B CAP1

3.13e-0410749314GO:0098657
GeneOntologyCellularComponenttransmembrane transporter complex

BEST2 KCNV2 KCNJ15 KCNK10 KCNK2 ABCD4 GRIA2 CACNG5 CATSPERG NDUFB5 CNGA1 CNGA2 GABRR3

4.77e-075239213GO:1902495
GeneOntologyCellularComponenttransporter complex

BEST2 KCNV2 KCNJ15 KCNK10 KCNK2 ABCD4 GRIA2 CACNG5 CATSPERG NDUFB5 CNGA1 CNGA2 GABRR3

8.40e-075509213GO:1990351
GeneOntologyCellularComponentmonoatomic ion channel complex

BEST2 KCNV2 KCNJ15 KCNK10 KCNK2 GRIA2 CACNG5 CATSPERG CNGA1 CNGA2 GABRR3

8.48e-073789211GO:0034702
GeneOntologyCellularComponentmembrane protein complex

AP4E1 CLTCL1 BEST2 KCNV2 KCNJ15 CLTC KCNK10 KCNK2 VPS41 ABCD4 LRP6 LRP5 GRIA2 CACNG5 GJB7 CATSPERG RNF139 NDUFB5 CNGA1 CNGA2 GABRR3

1.64e-0614989221GO:0098796
GeneOntologyCellularComponentclathrin complex

CLTCL1 CLTC VPS41

6.80e-069923GO:0071439
GeneOntologyCellularComponenttrans-Golgi network

PI4K2B AP4E1 CLTCL1 IFT88 CLTC PI4K2A BACE2 CRHR1

6.17e-05306928GO:0005802
GeneOntologyCellularComponentGolgi apparatus subcompartment

PI4K2B AP4E1 CLTCL1 IFT88 CLTC PI4K2A CHSY1 BACE2 CRHR1

1.46e-04443929GO:0098791
GeneOntologyCellularComponentWnt-Frizzled-LRP5/6 complex

LRP6 LRP5

1.90e-045922GO:1990851
GeneOntologyCellularComponentintracellular cyclic nucleotide activated cation channel complex

CNGA1 CNGA2

3.97e-047922GO:0017071
GeneOntologyCellularComponentperikaryon

SLC8A2 TRPM2 ASS1 PI4K2A GRIA2 CNGA2

4.58e-04223926GO:0043204
GeneOntologyCellularComponentpostsynaptic endocytic zone

CLTC GRIA2

1.03e-0311922GO:0098843
GeneOntologyCellularComponentsynaptic membrane

SLC6A9 SLC8A2 P2RX1 CLTC PI4K2A GRIA2 CACNG5 CRHR1 GABRR3

1.07e-03583929GO:0097060
GeneOntologyCellularComponentmembrane coat

AP4E1 CLTCL1 CLTC VPS41

1.24e-03106924GO:0030117
GeneOntologyCellularComponentcoated membrane

AP4E1 CLTCL1 CLTC VPS41

1.24e-03106924GO:0048475
GeneOntologyCellularComponentGolgi-associated vesicle

CLTCL1 CLTC VPS41 CNGA2

1.62e-03114924GO:0005798
GeneOntologyCellularComponentcytoplasmic vesicle membrane

PI4K2B SLC6A9 ATP13A4 CLTCL1 P2RX1 IFT88 TRPM2 CLTC VPS41 PI4K2A LRP6 GRIA2 BACE2 CNGA2

1.67e-0313079214GO:0030659
GeneOntologyCellularComponentendosome

PI4K2B AP4E1 SLC6A9 ATP13A4 CLTCL1 TBCK CLTC TBC1D12 VPS41 PI4K2A LRP6 BACE2 CRHR1

1.76e-0311679213GO:0005768
GeneOntologyCellularComponentvesicle membrane

PI4K2B SLC6A9 ATP13A4 CLTCL1 P2RX1 IFT88 TRPM2 CLTC VPS41 PI4K2A LRP6 GRIA2 BACE2 CNGA2

1.90e-0313259214GO:0012506
GeneOntologyCellularComponentclathrin coat

CLTCL1 CLTC VPS41

1.93e-0356923GO:0030118
GeneOntologyCellularComponentpostsynaptic membrane

SLC6A9 SLC8A2 P2RX1 GRIA2 CACNG5 CRHR1 GABRR3

2.08e-03405927GO:0045211
GeneOntologyCellularComponentWnt signalosome

LRP6 LRP5

2.21e-0316922GO:1990909
GeneOntologyCellularComponentvacuole

FUT10 GPC3 TRPM2 CLTC TBC1D12 VPS41 PI4K2A ABCD4 NHLRC3 GLB1L2 CAP1

2.21e-039139211GO:0005773
GeneOntologyCellularComponentplasma membrane protein complex

KCNV2 CLTC KCNK2 ABCD4 LRP6 LRP5 GRIA2 CACNG5 GJB7 CATSPERG

2.36e-037859210GO:0098797
GeneOntologyCellularComponentearly endosome membrane

PI4K2B ATP13A4 VPS41 PI4K2A LRP6

2.46e-03212925GO:0031901
GeneOntologyCellularComponentGolgi-associated vesicle membrane

CLTCL1 CLTC CNGA2

2.47e-0361923GO:0030660
GeneOntologyCellularComponentclathrin coat of trans-Golgi network vesicle

CLTCL1 CLTC

2.80e-0318922GO:0030130
GeneOntologyCellularComponentDNA polymerase complex

POLE DNA2

3.46e-0320922GO:0042575
GeneOntologyCellularComponentcation channel complex

KCNV2 KCNK2 CATSPERG CNGA1 CNGA2

3.83e-03235925GO:0034703
DomainCLH

CLTCL1 CLTC VPS41

1.23e-073943SM00299
DomainClathrin

CLTCL1 CLTC VPS41

4.26e-067943PF00637
DomainCHCR

CLTCL1 CLTC VPS41

4.26e-067943PS50236
DomainClathrin_H-chain/VPS_repeat

CLTCL1 CLTC VPS41

6.79e-068943IPR000547
Domain2pore_dom_K_chnl_TREK

KCNK10 KCNK2

2.51e-052942IPR003976
DomainClathrin_H-chain_propeller_rpt

CLTCL1 CLTC

2.51e-052942IPR022365
DomainClathrin-link

CLTCL1 CLTC

2.51e-052942PF09268
Domain-

CLTCL1 CLTC

2.51e-0529422.130.10.110
DomainLRP5/6

LRP6 LRP5

2.51e-052942IPR017049
DomainClathrin_H-chain_link/propller

CLTCL1 CLTC

2.51e-052942IPR016025
DomainClathrin_propel

CLTCL1 CLTC

2.51e-052942PF01394
DomainClathrin_heavy_chain

CLTCL1 CLTC

2.51e-052942IPR016341
DomainClathrin_H-chain_linker_core

CLTCL1 CLTC

2.51e-052942IPR015348
DomainClathrin_H-chain_propeller_N

CLTCL1 CLTC

2.51e-052942IPR001473
DomainLdl_recept_b

LRP6 LRP5 LRP1B

4.32e-0514943PF00058
DomainLDLRB

LRP6 LRP5 LRP1B

4.32e-0514943PS51120
Domain-

LRP6 LRP5 NHLRC3 LRP1B

4.32e-05399442.120.10.30
DomainLY

LRP6 LRP5 LRP1B

5.38e-0515943SM00135
DomainLDLR_classB_rpt

LRP6 LRP5 LRP1B

5.38e-0515943IPR000033
DomainClathrin_H-chain_linker

CLTCL1 CLTC

7.49e-053942IPR012331
Domain6-blade_b-propeller_TolB-like

LRP6 LRP5 NHLRC3 LRP1B

8.35e-0546944IPR011042
Domain-

CRNKL1 LRPPRC CLTCL1 IFT88 TTC23L CLTC VPS41

8.41e-052079471.25.40.10
DomainTBC

TBC1D8 TBCK TBC1D12 TBC1D9

1.07e-0449944SM00164
DomainRabGAP-TBC

TBC1D8 TBCK TBC1D12 TBC1D9

1.46e-0453944PF00566
DomainCLZ_dom

CNGA1 CNGA2

1.49e-044942IPR032406
DomainCLZ

CNGA1 CNGA2

1.49e-044942PF16526
DomainTBC_RABGAP

TBC1D8 TBCK TBC1D12 TBC1D9

1.69e-0455944PS50086
DomainRab-GTPase-TBC_dom

TBC1D8 TBCK TBC1D12 TBC1D9

1.69e-0455944IPR000195
DomainTPR-like_helical_dom

CRNKL1 LRPPRC CLTCL1 IFT88 TTC23L CLTC VPS41

1.75e-04233947IPR011990
DomainTB2_DP1_HVA22

REEP1 REEP3

3.71e-046942IPR004345
DomainTB2_DP1_HVA22

REEP1 REEP3

3.71e-046942PF03134
DomainGlyco_hydro_47

MAN1A2 MAN1A1

5.18e-047942PF01532
Domain-

MAN1A2 MAN1A1

5.18e-0479421.50.10.50
DomainGlyco_hydro_47

MAN1A2 MAN1A1

6.88e-048942IPR001382
DomainLDLR_class-A_CS

LRP6 LRP5 LRP1B

1.07e-0340943IPR023415
DomainNHL

NHLRC3 LRP1B

1.10e-0310942PF01436
DomainNHL_repeat

NHLRC3 LRP1B

1.10e-0310942IPR001258
DomainNTP_transf_2

OAS2 DNTT

1.34e-0311942PF01909
DomainPolymerase_NTP_transf_dom

OAS2 DNTT

1.34e-0311942IPR002934
DomainLdl_recept_a

LRP6 LRP5 LRP1B

1.50e-0345943PF00057
Domain-

LRP6 LRP5 LRP1B

1.60e-03469434.10.400.10
DomainLDLRA_1

LRP6 LRP5 LRP1B

1.81e-0348943PS01209
DomainLDLRA_2

LRP6 LRP5 LRP1B

1.92e-0349943PS50068
DomainLDrepeatLR_classA_rpt

LRP6 LRP5 LRP1B

1.92e-0349943IPR002172
DomainLDLa

LRP6 LRP5 LRP1B

1.92e-0349943SM00192
Domain2pore_dom_K_chnl

KCNK10 KCNK2

2.52e-0315942IPR003280
DomainIon_trans_dom

KCNV2 TRPM2 CNGA1 CNGA2

2.63e-03114944IPR005821
DomainIon_trans

KCNV2 TRPM2 CNGA1 CNGA2

2.63e-03114944PF00520
DomainGRAM

TBC1D8 TBC1D9

2.87e-0316942SM00568
DomaincNMP-bd_CS

CNGA1 CNGA2

2.87e-0316942IPR018488
DomainPI3/4_kinase_cat_dom

PI4K2B PI4K2A

3.64e-0318942IPR000403
DomainPI3_PI4_kinase

PI4K2B PI4K2A

3.64e-0318942PF00454
DomainPI3_4_KINASE_3

PI4K2B PI4K2A

3.64e-0318942PS50290
DomainPI3_4_KINASE_1

PI4K2B PI4K2A

3.64e-0318942PS00915
DomainPI3_4_KINASE_2

PI4K2B PI4K2A

3.64e-0318942PS00916
DomainK_chnl_dom

KCNK10 KCNK2

4.95e-0321942IPR013099
DomainIon_trans_2

KCNK10 KCNK2

4.95e-0321942PF07885
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

BPTF FUT10 LRPPRC CMIP SLC16A9 TBCK TRPM2 ASS1 VPS41 LRP5 ENPP5 FRYL CATSPERG CFAP69 NDUFB5 REEP3

2.30e-061489941628611215
Pubmed

LRP2 mediates folate uptake in the developing neural tube.

LRP6 LRP5 LRP1B

3.11e-061194324639464
Pubmed

Identification and characterization of a novel Tre-2/Bub2/Cdc16 (TBC) protein that possesses Rab3A-GAP activity.

TBC1D8 TBCK TBC1D12 TBC1D9

5.70e-064394419077034
Pubmed

Characterization of a second human clathrin heavy chain polypeptide gene (CLH-22) from chromosome 22q11.

CLTCL1 CLTC

7.23e-0629428733129
Pubmed

Evidence against a human cell-specific role for LRP6 in anthrax toxin entry.

LRP6 LRP5

7.23e-06294218350154
Pubmed

AMP-activated protein kinase inhibits TREK channels.

KCNK10 KCNK2

7.23e-06294219840997
Pubmed

Clinical Phenotype and Relevance of LRP5 and LRP6 Variants in Patients With Early-Onset Osteoporosis (EOOP).

LRP6 LRP5

7.23e-06294233118644
Pubmed

Dissecting molecular differences between Wnt coreceptors LRP5 and LRP6.

LRP6 LRP5

7.23e-06294221887268
Pubmed

Modulation of K2P 2.1 and K2P 10.1 K(+) channel sensitivity to carvedilol by alternative mRNA translation initiation.

KCNK10 KCNK2

7.23e-06294225168769
Pubmed

Expression and effects of modulation of the K2P potassium channels TREK-1 (KCNK2) and TREK-2 (KCNK10) in the normal human ovary and epithelial ovarian cancer.

KCNK10 KCNK2

7.23e-06294223479219
Pubmed

PAR1&2 driven placenta EVT invasion act via LRP5/6 as coreceptors.

LRP6 LRP5

7.23e-06294233136328
Pubmed

Lack of association of LRP5 and LRP6 polymorphisms with type 2 diabetes mellitus in the Japanese population.

LRP6 LRP5

7.23e-06294218493104
Pubmed

LDL receptor-related proteins 5 and 6 in Wnt/beta-catenin signaling: arrows point the way.

LRP6 LRP5

7.23e-06294215084453
Pubmed

CHC22 and CHC17 clathrins have distinct biochemical properties and display differential regulation and function.

CLTCL1 CLTC

7.23e-06294229097553
Pubmed

Lrp5 and Lrp6 are required for maintaining self-renewal and differentiation of hematopoietic stem cells.

LRP6 LRP5

7.23e-06294230668923
Pubmed

Extracellular acidification exerts opposite actions on TREK1 and TREK2 potassium channels via a single conserved histidine residue.

KCNK10 KCNK2

7.23e-06294219667202
Pubmed

Both LRP5 and LRP6 receptors are required to respond to physiological Wnt ligands in mammary epithelial cells and fibroblasts.

LRP6 LRP5

7.23e-06294222433869
Pubmed

Co-deletion of Lrp5 and Lrp6 in the skeleton severely diminishes bone gain from sclerostin antibody administration.

LRP6 LRP5

7.23e-06294233164872
Pubmed

The glycine hinge of transmembrane segment 2 modulates the subcellular localization and gating properties in TREK channels.

KCNK10 KCNK2

7.23e-06294228676394
Pubmed

LRP5/6 directly bind to Frizzled and prevent Frizzled-regulated tumour metastasis.

LRP6 LRP5

7.23e-06294225902418
Pubmed

Wnt-Lrp5 signaling regulates fatty acid metabolism in the osteoblast.

LRP6 LRP5

7.23e-06294225802278
Pubmed

The clathrin heavy chain isoform CHC22 functions in a novel endosomal sorting step.

CLTCL1 CLTC

7.23e-06294220065094
Pubmed

Formation of Functional Heterodimers by TREK-1 and TREK-2 Two-pore Domain Potassium Channel Subunits.

KCNK10 KCNK2

7.23e-06294227129242
Pubmed

The high-resolution crystal structure of phosphatidylinositol 4-kinase IIβ and the crystal structure of phosphatidylinositol 4-kinase IIα containing a nucleoside analogue provide a structural basis for isoform-specific inhibitor design.

PI4K2B PI4K2A

7.23e-06294226143926
Pubmed

The involvement of the canonical Wnt-signaling receptor LRP5 and LRP6 gene variants with ADHD and sexual dimorphism: Association study and meta-analysis.

LRP6 LRP5

7.23e-06294230474181
Pubmed

In Adult Skeletal Muscles, the Co-Receptors of Canonical Wnt Signaling, Lrp5 and Lrp6, Determine the Distribution and Size of Fiber Types, and Structure and Function of Neuromuscular Junctions.

LRP6 LRP5

7.23e-06294236552732
Pubmed

Idiopathic Juvenile Osteoporosis: Clinical Experience from a Single Centre and Screening of LRP5 and LRP6 Genes.

LRP6 LRP5

7.23e-06294225783012
Pubmed

Gene targeting approaches in mice: assessing the roles of LRP5 and LRP6 in osteoblasts.

LRP6 LRP5

7.23e-06294219147944
Pubmed

Decreased BMD and limb deformities in mice carrying mutations in both Lrp5 and Lrp6.

LRP6 LRP5

7.23e-06294215537447
Pubmed

Distinct roles of LRP5 and LRP6 in Wnt signaling regulation in the retina.

LRP6 LRP5

7.23e-06294233545636
Pubmed

LRP5 and LRP6 are not required for protective antigen-mediated internalization or lethality of anthrax lethal toxin.

LRP6 LRP5

7.23e-06294217335347
Pubmed

Migraine-Associated TRESK Mutations Increase Neuronal Excitability through Alternative Translation Initiation and Inhibition of TREK.

KCNK10 KCNK2

7.23e-06294230573346
Pubmed

Six novel missense mutations in the LDL receptor-related protein 5 (LRP5) gene in different conditions with an increased bone density.

LRP6 LRP5

7.23e-06294212579474
Pubmed

The Wnt co-receptor Lrp6 is required for normal mouse mammary gland development.

LRP6 LRP5

7.23e-06294219503830
Pubmed

LRP5-/6 gene polymorphisms and its association with risk of abnormal bone mass in postmenopausal women.

LRP6 LRP5

7.23e-06294237202775
Pubmed

Wnt receptors, bone mass, and fractures: gene-wide association analysis of LRP5 and LRP6 polymorphisms with replication.

LRP6 LRP5

7.23e-06294220926594
Pubmed

Common genetic variation of the low-density lipoprotein receptor-related protein 5 and 6 genes determines fracture risk in elderly white men.

LRP6 LRP5

7.23e-06294216355283
Pubmed

Haemorrhagic snake venom metalloproteases and human ADAMs cleave LRP5/6, which disrupts cell-cell adhesions in vitro and induces haemorrhage in vivo.

LRP6 LRP5

7.23e-06294228425175
Pubmed

Canonical Wnt Signaling in CD11c+ APCs Regulates Microbiota-Induced Inflammation and Immune Cell Homeostasis in the Colon.

LRP6 LRP5

2.16e-05394229602775
Pubmed

Type II PI4-kinases control Weibel-Palade body biogenesis and von Willebrand factor structure in human endothelial cells.

PI4K2B PI4K2A

2.16e-05394227068535
Pubmed

Expression of cyclic nucleotide-gated cation channels in non-sensory tissues and cells.

CNGA1 CNGA2

2.16e-0539427532814
Pubmed

Characterization of a cDNA encoding a novel human Golgi alpha 1, 2-mannosidase (IC) involved in N-glycan biosynthesis.

MAN1A2 MAN1A1

2.16e-05394210915796
Pubmed

Functional equivalence of the clathrin heavy chains CHC17 and CHC22 in endocytosis and mitosis.

CLTCL1 CLTC

2.16e-05394219509056
Pubmed

Disabled-2 (Dab2) inhibits Wnt/β-catenin signalling by binding LRP6 and promoting its internalization through clathrin.

CLTC LRP6

2.16e-05394222491013
Pubmed

Multivesicular GSK3 sequestration upon Wnt signaling is controlled by p120-catenin/cadherin interaction with LRP5/6.

LRP6 LRP5

2.16e-05394224412065
Pubmed

LRP5 in premature adrenarche and in metabolic characteristics of prepubertal children.

LRP6 LRP5

2.16e-05394218721193
Pubmed

tPA regulates neurite outgrowth by phosphorylation of LRP5/6 in neural progenitor cells.

LRP6 LRP5

2.16e-05394223925701
Pubmed

Structural insight into the mechanisms of Wnt signaling antagonism by Dkk.

LRP6 LRP5

2.16e-05394218524778
Pubmed

Canonical wnt signaling in dendritic cells regulates Th1/Th17 responses and suppresses autoimmune neuroinflammation.

LRP6 LRP5

2.16e-05394225710911
Pubmed

Phospholipase D2 specifically regulates TREK potassium channels via direct interaction and local production of phosphatidic acid.

KCNK10 KCNK2

2.16e-05394225197053
Pubmed

The structural basis of DKK-mediated inhibition of Wnt/LRP signaling.

LRP6 LRP5

2.16e-05394222589387
Pubmed

Clathrin promotes centrosome integrity in early mitosis through stabilization of centrosomal ch-TOG.

CLTCL1 CLTC

2.16e-05394222891263
Pubmed

How ion channels sense mechanical force: insights from mechanosensitive K2P channels TRAAK, TREK1, and TREK2.

KCNK10 KCNK2

2.16e-05394226332952
Pubmed

Role of the TREK2 potassium channel in cold and warm thermosensation and in pain perception.

KCNK10 KCNK2

2.16e-05394225239074
Pubmed

Wnt co-receptor LRP5/6 overexpression confers protection against hydrogen peroxide-induced neurotoxicity and reduces tau phosphorylation in SH-SY5Y cells.

LRP6 LRP5

2.16e-05394225959626
Pubmed

Opposing Roles of Wnt Inhibitors IGFBP-4 and Dkk1 in Cardiac Ischemia by Differential Targeting of LRP5/6 and β-catenin.

LRP6 LRP5

2.16e-05394227803037
Pubmed

Two structural and functional domains of MESD required for proper folding and trafficking of LRP5/6.

LRP6 LRP5

2.16e-05394221397183
Pubmed

Structural basis of Wnt signaling inhibition by Dickkopf binding to LRP5/6.

LRP6 LRP5

2.16e-05394222000856
Pubmed

Lysophosphatidic acid-operated K+ channels.

KCNK10 KCNK2

2.16e-05394215572365
Pubmed

Tension activation of mechanosensitive two-pore domain K+ channels TRAAK, TREK-1, and TREK-2.

KCNK10 KCNK2

2.16e-05394238605031
Pubmed

Dysfunction of KCNK potassium channels impairs neuronal migration in the developing mouse cerebral cortex.

KCNK10 KCNK2

2.16e-05394223236211
Pubmed

Radiographic osteoarthritis at three joint sites and FRZB, LRP5, and LRP6 polymorphisms in two population-based cohorts.

LRP6 LRP5

2.16e-05394218406176
Pubmed

Behavioral characterization of mice lacking Trek channels.

KCNK10 KCNK2

2.16e-05394222973213
Pubmed

Isolation of a mouse Golgi mannosidase cDNA, a member of a gene family conserved from yeast to mammals.

MAN1A2 MAN1A1

2.16e-0539428144579
Pubmed

Molecular simulation analysis of the structure complex of C2 domains of DKK family members and β-propeller domains of LRP5/6: explaining why DKK3 does not bind to LRP5/6.

LRP6 LRP5

2.16e-05394224743782
Pubmed

Type II phosphatidylinositol 4-kinase beta is a cytosolic and peripheral membrane protein that is recruited to the plasma membrane and activated by Rac-GTP.

PI4K2B PI4K2A

2.16e-05394212324459
Pubmed

Mixing and matching TREK/TRAAK subunits generate heterodimeric K2P channels with unique properties.

KCNK10 KCNK2

2.16e-05394227035965
Pubmed

Loss of endothelial glucocorticoid receptor promotes angiogenesis via upregulation of Wnt/β-catenin pathway.

LRP6 LRP5

2.16e-05394233650028
Pubmed

Lrp5 and Lrp6 play compensatory roles in mouse intestinal development.

LRP6 LRP5

2.16e-05394221866564
Pubmed

Clathrin isoform CHC22, a component of neuromuscular and myotendinous junctions, binds sorting nexin 5 and has increased expression during myogenesis and muscle regeneration.

CLTCL1 CLTC

2.16e-05394215133132
Pubmed

Molecular cloning, chromosomal mapping and tissue-specific expression of a novel human alpha1,2-mannosidase gene involved in N-glycan maturation.

MAN1A2 MAN1A1

2.16e-0539429592125
Pubmed

Anti-LRP5/6 VHHs promote differentiation of Wnt-hypersensitive intestinal stem cells.

LRP6 LRP5

2.16e-05394230664649
Pubmed

Peptide-based mediated disruption of N-cadherin-LRP5/6 interaction promotes Wnt signaling and bone formation.

LRP6 LRP5

2.16e-05394222576936
Pubmed

Importance of the CNGA4 channel gene for odor discrimination and adaptation in behaving mice.

CNGA1 CNGA2

2.16e-05394212649326
Pubmed

Depletion of canonical Wnt signaling components has a neuroprotective effect on midbrain dopaminergic neurons in an MPTP-induced mouse model of Parkinson's disease.

LRP6 LRP5

2.16e-05394225009587
Pubmed

Characterization of type II phosphatidylinositol 4-kinase isoforms reveals association of the enzymes with endosomal vesicular compartments.

PI4K2B PI4K2A

2.16e-05394211923287
Pubmed

TRAP1 Regulates Wnt/β-Catenin Pathway through LRP5/6 Receptors Expression Modulation.

LRP6 LRP5

2.16e-05394233065966
Pubmed

MESD is essential for apical localization of megalin/LRP2 in the visceral endoderm.

LRP6 LRP5 LRP1B

2.45e-052194321337463
Pubmed

Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.

P2RX1 KCNV2 KCNJ15 KCNK2 CACNG5

3.91e-0513994516985003
Pubmed

Characterization of the interaction of sclerostin with the low density lipoprotein receptor-related protein (LRP) family of Wnt co-receptors.

LRP6 LRP5

4.32e-05494222696217
Pubmed

Bone overgrowth-associated mutations in the LRP4 gene impair sclerostin facilitator function.

LRP6 LRP5

4.32e-05494221471202
Pubmed

Distinct plasma-membrane PtdIns(4)P and PtdIns(4,5)P2 dynamics in secretagogue-stimulated beta-cells.

PI4K2B PI4K2A

4.32e-05494220375060
Pubmed

Lrp5/6 are required for cerebellar development and for suppressing TH expression in Purkinje cells via β-catenin.

LRP6 LRP5

4.32e-05494226772978
Pubmed

The Wnt-β-Catenin-IL-10 Signaling Axis in Intestinal APCs Protects Mice from Colitis-Associated Colon Cancer in Response to Gut Microbiota.

LRP6 LRP5

4.32e-05494232917787
Pubmed

Elevated expression of TREK-TRAAK K2P channels in the retina of adult rd1 mice.

KCNK10 KCNK2

4.32e-05494231236347
Pubmed

Wnt co-receptors Lrp5 and Lrp6 differentially mediate Wnt3a signaling in osteoblasts.

LRP6 LRP5

4.32e-05494229176883
Pubmed

Bone density ligand, Sclerostin, directly interacts with LRP5 but not LRP5G171V to modulate Wnt activity.

LRP6 LRP5

4.32e-05494217002572
Pubmed

Oligomerization of Frizzled and LRP5/6 protein initiates intracellular signaling for the canonical WNT/β-catenin pathway.

LRP6 LRP5

4.32e-05494230361437
Pubmed

Truncated mutants of the putative Wnt receptor LRP6/Arrow can stabilize beta-catenin independently of Frizzled proteins.

LRP6 LRP5

4.32e-05494215064719
Pubmed

Differential expression of DKK-1 binding receptors on stromal cells and myeloma cells results in their distinct response to secreted DKK-1 in myeloma.

LRP6 LRP5

4.32e-05494220846389
Pubmed

Characterization of the Kremen-binding site on Dkk1 and elucidation of the role of Kremen in Dkk-mediated Wnt antagonism.

LRP6 LRP5

4.32e-05494218502762
Pubmed

Novel mechanism of Wnt signalling inhibition mediated by Dickkopf-1 interaction with LRP6/Arrow.

LRP6 LRP5

4.32e-05494211433302
Pubmed

SOST is a ligand for LRP5/LRP6 and a Wnt signaling inhibitor.

LRP6 LRP5

4.32e-05494215908424
Pubmed

Lrp5 and Lrp6 exert overlapping functions in osteoblasts during postnatal bone acquisition.

LRP6 LRP5

4.32e-05494223675479
Pubmed

Shh Plays an Inhibitory Role in Cusp Patterning by Regulation of Sostdc1.

LRP6 LRP5

4.32e-05494230325689
Pubmed

Tailored tetravalent antibodies potently and specifically activate Wnt/Frizzled pathways in cells, organoids and mice.

LRP6 LRP5

4.32e-05494231452509
Pubmed

Caprin-2 enhances canonical Wnt signaling through regulating LRP5/6 phosphorylation.

LRP6 LRP5

4.32e-05494218762581
Pubmed

The role of Lrp5/6 in cardiac valve disease: experimental hypercholesterolemia in the ApoE-/- /Lrp5-/- mice.

LRP6 LRP5

4.32e-05494221678468
Pubmed

Critical Endothelial Regulation by LRP5 during Retinal Vascular Development.

LRP6 LRP5

4.32e-05494227031698
Pubmed

HIP1 functions in clathrin-mediated endocytosis through binding to clathrin and adaptor protein 2.

CLTCL1 CLTC

4.32e-05494211517213
Cytoband4q31.3

SH3D19 FHIP1A

1.86e-03319424q31.3
CytobandEnsembl 112 genes in cytogenetic band chr10q21

SLC16A9 DNA2 REEP3

1.87e-03118943chr10q21
CytobandXq21.1

GPR174 SATL1

2.10e-0333942Xq21.1
GeneFamilyLow density lipoprotein receptors

LRP6 LRP5 LRP1B

9.22e-0613593634
GeneFamilyMannosidases alpha class 1

MAN1A2 MAN1A1

6.26e-0545921193
GeneFamilyReceptor accessory proteins

REEP1 REEP3

1.56e-046592717
GeneFamilyCyclic nucleotide gated channels

CNGA1 CNGA2

4.63e-0410592250
GeneFamilyWD repeat domain containing|GRAM domain containing|BEACH domain containing

TBC1D8 TBC1D9

7.98e-04135921146
GeneFamilyPotassium two pore domain channel subfamily K

KCNK10 KCNK2

1.07e-0315592277
GeneFamilyDNA polymerases

POLE DNTT

2.53e-0323592535
GeneFamilyGCN5 related N-acetyltransferases

SAT1 SATL1

2.76e-03245921134
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TMC2 POLE NEB LRP1B DNAH9 CNGA1

1.24e-06162946bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellControl-B_cells-Plasma_cells|Control / group, cell type (main and fine annotations)

MAN1A1 P2RX1 CHST15 PAH TXNDC11 TBC1D9

1.95e-06175946fb23858cfce71509cafbe0d9728e678012ff2962
ToppCellControl-Endothelial-VE_Venous|Endothelial / Disease state, Lineage and Cell class

SULT1B1 CMIP SAT1 ASS1 UGCG CHSY1

3.13e-061909464e30155203b4a8c5e496fcbe9348b67b98ebc625
ToppCellControl-Myeloid-ncMonocyte|Myeloid / Disease state, Lineage and Cell class

TBC1D8 P2RX1 SAT1 CHST15 CHSY1 ARAP2

3.43e-061939463479c01aaae7afd7e02d00e0cb21951c0106a0fd
ToppCellhuman_hepatoblastoma-Tumor_cells|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

GPC3 SH3D19 PAH LRP6 LRP5 CPB2

3.43e-06193946503a979328c68b096680b71359a26f02fafdff35
ToppCellBronchial-NucSeq-Immune_Lymphocytic-B-B_plasma-B_plasma_IgG|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MAN1A1 P2RX1 CHST15 PAH TXNDC11 TBC1D9

3.75e-06196946fd18a9ae8401121ae276adff1a85d5f938e2df91
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chodl|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CCDC83 MAN1A1 ASS1 BACE2 DNAH9

1.37e-05144945b622b605f7ec6083ec06c8ea0fd171e07c52f3de
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKK1 TMC2 BEST2 POLE LRP1B

1.41e-0514594596712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCellAdult-Immune-mast_cell-D122|Adult / Lineage, Cell type, age group and donor

CCDC83 TMC2 P2RX1 BACE2 LRP1B

1.95e-051559457c9de0591d1bf756b8e268b278bbe10bd5415dcd
ToppCellAdult-Epithelial-lung_goblet_cell-D175|Adult / Lineage, Cell type, age group and donor

SLC16A9 KCNV2 ASS1 BACE2 PRDM14

2.56e-051649456e6aedb61f8e195d52e028fdda750a29bb14e57e
ToppCellfacs-Marrow-B-cells-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AP4E1 SLC6A9 P2RX1 ZNF277 ABCD4

2.71e-0516694513027ae342994db4540e64eb910df1f42b160931
ToppCellfacs-Marrow-B-cells-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AP4E1 SLC6A9 P2RX1 ZNF277 ABCD4

2.71e-05166945b21e45bd43f26149b9cd6e45c19241c82d54fb2f
ToppCell5'-Adult-LymphNode-Hematopoietic-Plasma_cells-IgG_plasma_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MAN1A1 P2RX1 CHST15 TXNDC11 TBC1D9

2.87e-05168945f5a18123f84c62211d9279e9c41e90122e4c4895
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1.5|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

FUT10 IFT88 SH3D19 TBCK OAS2

2.87e-0516894594cded2e953c0970bf2f3dbe0ce46bd77a5ed8c7
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-Plasmacytoid_Dendritic_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

P2RX1 CHST15 TRPM2 UGCG KCNK10

3.12e-0517194539c8ae139e449217091e1481eb5e2aafb8f69a1c
ToppCellmetastatic_Brain-Fibroblasts-Undetermined|Fibroblasts / Location, Cell class and cell subclass

TBC1D8 PI4K2B FUT10 SLC16A9 DNAH9

3.21e-05172945c3822ff7329c3ac38c68c5c38cd67c390682e2a6
ToppCellAdult-Epithelial-lung_neuroendocrine_cell_(PNEC)|Adult / Lineage, Cell type, age group and donor

PAH KCNK10 GRIA2 ENPP5 SATL1

3.49e-051759454db1a3c284488b3f6de7568363f176d74e2a4587
ToppCellAdult-Epithelial-lung_neuroendocrine_cell_(PNEC)-D231|Adult / Lineage, Cell type, age group and donor

PAH KCNK10 GRIA2 ENPP5 SATL1

3.49e-051759458d9f44a2633b71fb4d2b4a7d9530f954e07c4a18
ToppCell356C-Lymphocytic-NK_cells-NK_cell_A2|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

P2RX1 SLC16A9 LRP5 BACE2 TBC1D9

3.58e-05176945052b54c4337ca728974a106b6dbd3b72dd28eb23
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

P2RX1 UGCG KCNK10 GABRR3 DNTT

3.68e-051779458887ff6341eb070bdaa890cc2cd7745f0cf1b0af
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

P2RX1 UGCG KCNK10 GABRR3 DNTT

3.68e-05177945507f06d31ab773099c9431b6f433899dc97b5566
ToppCellfacs-Heart-LV-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC8A2 P2RX1 REEP1 GPC3 CACNG5

3.89e-051799458da6863edc756540bb097cc7221c1408640d9bb4
ToppCellfacs-Heart-LV-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC8A2 P2RX1 REEP1 GPC3 CACNG5

3.89e-05179945f39c13c99a07d009cc677e363ffe089089c64916
ToppCelldroplet-Lung-LUNG-30m-Epithelial-type_II_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PI4K2B CCDC83 ATP13A4 KCNJ15 CNGA2

4.10e-05181945cadb18fc73031eb9f779599e15cd7861337fee78
ToppCelldroplet-Lung-LUNG-30m-Epithelial-Alveolar_Epithelial_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PI4K2B CCDC83 ATP13A4 KCNJ15 CNGA2

4.10e-0518194585bec4d3f255f4c61c790325eeb50ad38f709ef2
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC16A9 KCNJ15 ASS1 PAH KCNK10

4.20e-05182945e1e58176f533092b6b974ca1ce8b02192a6e193d
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC16A9 KCNJ15 ASS1 PAH KCNK10

4.20e-0518294557bb5a2da976464ba7c4460106bd9f692008ebd9
ToppCellCOVID-19-B_cells-Plasma_cells|COVID-19 / group, cell type (main and fine annotations)

MAN1A2 MAN1A1 P2RX1 CHST15 TXNDC11

4.32e-05183945130c109f63a5e3c8f83cb96e32f4addf513b6415
ToppCellCOVID-19-B_cells|COVID-19 / group, cell type (main and fine annotations)

MAN1A2 MAN1A1 P2RX1 CHST15 TXNDC11

4.32e-051839452c016bb59f131a0e821853b085289a3583f0a729
ToppCellpdx-Tumor_cells-T0|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

TBC1D8 CMIP GPC3 TBCK PAH

4.54e-051859451d874608aa2062024323512f68889219471b2f00
ToppCellpdx|World / Sample and Cell Type and Tumor Cluster (all cells)

TBC1D8 BPTF CMIP GPC3 TBCK

4.66e-05186945de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCellpdx-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

TBC1D8 BPTF CMIP GPC3 TBCK

4.66e-051869450b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC16A9 KCNJ15 ASS1 PAH KCNK10

4.78e-051879451b82920588f9e26ef1db244d452736d75fcfd342
ToppCellhuman_hepatoblastoma-Tumor_cells-T2|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

CMIP GPC3 TBCK PAH CPB2

4.78e-05187945f3e37c18ac6471c7992609bbddfa4975571c815c
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC16A9 KCNJ15 ASS1 PAH KCNK10

4.78e-05187945c1e4c0345f9bfa0538730bad5ff3fa5240168b25
ToppCellwk_15-18-Hematologic-Myeloid-Basophil|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

GPR174 P2RX1 TRPM2 OAS2 FHIP1A

4.91e-051889453638d85452de15a060146628fbbad9d2a36feb13
ToppCellCOVID-19-kidney-DCT|kidney / Disease (COVID-19 only), tissue and cell type

SAT1 BACE2 LRP1B FHIP1A TBC1D9

4.91e-05188945df1fd0819d301679f3c9ea404e942e39095912eb
ToppCellIPF-Myeloid-ncMonocyte|Myeloid / Disease state, Lineage and Cell class

TBC1D8 P2RX1 SAT1 CHST15 CHSY1

5.03e-051899455c22d2d935f7bb270260b8bc6be67b565ec401bf
ToppCellCOPD-Myeloid-ncMonocyte|World / Disease state, Lineage and Cell class

TBC1D8 P2RX1 SAT1 CHST15 CHSY1

5.16e-05190945aece860b5609ad5a8fc920d685f0d0ec71bf9018
ToppCellCOPD-Myeloid-ncMonocyte|Myeloid / Disease state, Lineage and Cell class

TBC1D8 P2RX1 SAT1 CHST15 CHSY1

5.16e-05190945ed978cd5d9da87b49878a330e362762c487f849f
ToppCellIPF-Myeloid-ncMonocyte|World / Disease state, Lineage and Cell class

TBC1D8 P2RX1 SAT1 CHST15 CHSY1

5.16e-05190945f9c2a13c7f6460e3b348581be855b7281c8f70b5
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-secretory_cell-Epi-Secretory|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

SLC6A9 SLC16A9 ASS1 LRP5 FHIP1A

5.42e-051929458899d81306770adda893b5e146df1253971754c5
ToppCellIPF-Myeloid-ncMonocyte|IPF / Disease state, Lineage and Cell class

TBC1D8 P2RX1 SAT1 CHST15 CHSY1

5.42e-05192945e9fb8c57d8094f70fb492909b2bec40aa5f2e5b8
ToppCellLV-08._Macrophage|LV / Chamber and Cluster_Paper

CMIP MAN1A1 CHST15 TRPM2 ARAP2

5.42e-051929457be12d580aaf2f2f1562203fcad3a44639b8c5a6
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-secretory_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

SLC6A9 SLC16A9 ASS1 LRP5 FHIP1A

5.42e-051929455fda9a465c9f77c7fa1a3ea07a2b0374bbc23b2a
ToppCellCOPD-Myeloid-ncMonocyte|COPD / Disease state, Lineage and Cell class

TBC1D8 P2RX1 SAT1 CHST15 CHSY1

5.56e-05193945936ca95995599356b794fba32bfd82d8de339365
ToppCellLA-08._Macrophage|World / Chamber and Cluster_Paper

CMIP MAN1A1 CHST15 TRPM2 ARAP2

5.69e-05194945c1805572bcc11b1cd29083329d7b5911489fb758
ToppCell(5)_Plasma_IgM|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

MAN1A1 P2RX1 SAT1 CHST15 TXNDC11

5.69e-0519494547c0f7a1c39ba0836e40ea3ca8066457c0951575
ToppCellCOPD-Endothelial-VE_Peribronchial|Endothelial / Disease state, Lineage and Cell class

LRPPRC CMIP UGCG BACE2 ARAP2

5.69e-051949458dcde77767b23e75360adb316cdccf56a00e3726
ToppCellControl-Myeloid-ncMonocyte|Control / Disease state, Lineage and Cell class

TBC1D8 P2RX1 SAT1 CHST15 CHSY1

5.83e-05195945fcb05948e7480dc53f06f3fc9b9c3fc129874edd
ToppCellLA-08._Macrophage|LA / Chamber and Cluster_Paper

CMIP MAN1A1 CHST15 TRPM2 ARAP2

5.83e-051959455e1d5bdb8874091f5a2b1d0a8cc9008165718a97
ToppCellControl-Myeloid-ncMonocyte|World / Disease state, Lineage and Cell class

TBC1D8 P2RX1 SAT1 CHST15 CHSY1

5.83e-05195945b4444b67a709e82b8e2ee510924c3152cb88b051
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_naive-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TBC1D8 P2RX1 SAT1 CHST15 TTC23L

6.12e-051979454a6eff66a17c5e89bda61d887b736f5c62b93bd7
ToppCellBronchial-NucSeq-Immune_Lymphocytic-B-B_plasma|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MAN1A1 P2RX1 CHST15 PAH TXNDC11

6.27e-05198945567fcf882c8612356946240843525b786f3c8dbe
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th-Inhibitory_Neuron.Th.Nefl_(Neurofilament_state)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

ANKK1 CPB2 DNTT

1.26e-044694337ea73d291e35b6865bd3ea4857275a6e5b299d1
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th-Inhibitory_Neuron.Th.Nefl_(Neurofilament_state)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

ANKK1 CPB2 DNTT

1.26e-044694369e9c8cbae3d15bd0823b8c6e48a9d2b9815296b
ToppCellILEUM-non-inflamed-(3)_MNP-(3)_moDC|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

TBC1D8 SAT1 NHLRC3 TBC1D9

1.92e-04135944b7a792a7c0c22d8b703509f134115f0e394d7de0
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Excitatory_Neuron.Slc17a7.Fezf2-Efna5_(Subiculum)|Hippocampus / BrainAtlas - Mouse McCarroll V32

GARIN4 TMC2 SATL1

2.14e-0455943358f064742bfa96d4809c64d69929d08c6003857
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Excitatory_Neuron.Slc17a7.Fezf2-Efna5_(Subiculum)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

GARIN4 TMC2 SATL1

2.14e-04559433af3086910affe70f85734cf9099bd8d8b8eafe4
ToppCelldroplet-Liver-Npc-18m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SULT1B1 ASS1 PAH DNTT

2.72e-041489444ccf87f3e0d2c61148285979ae92cd41778fa321
ToppCelldroplet-Liver-Npc-18m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SULT1B1 ASS1 PAH DNTT

2.72e-04148944981e205cc8a6f6d2a35dc95c5a93ed9193a236b9
ToppCellEntopeduncular-Macroglia-OLIGODENDROCYTE-O1-Trf-Oligodendrocyte.Trf.Serpinb1a_(Serpinb1a)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

ANKK1 SULT1B1 BEST2

2.77e-046094348adafeec1810bce5f118fa63d4a8ee7ab9ca0f7
ToppCellEntopeduncular-Macroglia-OLIGODENDROCYTE-O1-Trf-Oligodendrocyte.Trf.Serpinb1a_(Serpinb1a)-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

ANKK1 SULT1B1 BEST2

2.77e-0460943a83afb89dbfc2e1cdfce57320d89c980bd8fb820
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-14|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ATP13A4 GPR174 BACE2 TBC1D9

2.87e-041509444bdcdce40f54580c7a4e1416b468e657ba8874fc
ToppCellfacs-Liver-Non-hepatocytes-3m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM2 OAS2 NHLRC3 TBC1D9

3.02e-04152944b61d2f6ee819c8dd4b4b601a8bc8388b1983de58
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Myeloid-Dendritic-conventional_dendritic_cell|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TBC1D8 FBXW8 TMC2 CNGA1

3.09e-04153944ee6f4770c6e35d59bdeec5b0ecb10119fa8c3ca5
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Myeloid-Dendritic|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TBC1D8 FBXW8 TMC2 CNGA1

3.09e-04153944a35149a0c8b4ec9ad27cc4b3d34fba3b8714a6a2
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GPR174 POLE ASS1 CNGA1

3.09e-041539440ad401cb70b9edfc6ae6ccba6879c6c2b6c4d296
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Myeloid-Dendritic-conventional_dendritic_cell-DC_c2-CD1C|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TBC1D8 FBXW8 TMC2 CNGA1

3.09e-0415394490cd6efda83c0b4b80eae2c90e7ff45dfd936dc2
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Granulocytic|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

P2RX1 CPB2 SATL1 DNA2

3.25e-0415594451f6447945389649d99dcf7603b396195c631ead
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Granulocytic-Mast_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

P2RX1 CPB2 SATL1 DNA2

3.25e-0415594423dc71cab28094ca0ac4d2baf4e24871ed107781
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-pDCs|Myeloid_cells / Location, Cell class and cell subclass

POLE UGCG KCNK10 FHIP1A

3.33e-0415694419472ef1642c2ad333aa3ce3675a25c6ab1d4556
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GPR174 POLE UGCG CHSY1

3.33e-0415694433deda19f06172079ef1dd49fd54d66da1e7fb14
ToppCell367C-Lymphocytic-NK_cells-NK_cell_D2|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

REEP1 ASS1 OAS2 TXNDC11

3.33e-041569440b3630fd4479291599e1674e87eba6f93877ac3a
ToppCelldroplet-Liver-Hepatocytes-21m-Epithelial-Hepatocyte_(Midlobular)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SULT1B1 ASS1 PAH DNTT

3.41e-041579445af1b77dd08cf7f3b629e0f59defdf1ebee5cc3e
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal-cortical_neurons_1|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

SLC6A9 GRIA2 DNA2 RABL3

3.49e-041589441f94622186d8329357fa06785e03eeacf29ab1ce
ToppCelldroplet-Kidney-nan-18m-Lymphocytic-CD45|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D8 IQCH TRPM2 TBC1D9

3.49e-04158944e0b862e4b9ebaa12869640b5d18d5fa852861bef
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B-Plasma_Cell-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MAN1A1 P2RX1 CHST15 TXNDC11

3.49e-041589446b51e5ee08e23924f5edbaf0a845a9232fb7ff7a
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B-Plasma_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MAN1A1 P2RX1 CHST15 TXNDC11

3.49e-041589448dd83a2a4c2ec9cdc3a03df8b51ee22bee1c2888
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMC2 IQCH CNGA1 CNGA2

3.49e-04158944f296ca24fdedc33f1d24b79e7660763114ce7fa3
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMC2 IQCH CNGA1 CNGA2

3.49e-041589448c7108f2c40d97a317762ba0b8eca76542b2ebaf
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKK1 KCNV2 LRP1B DNAH9

3.66e-04160944c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellCOVID_non-vent-Lymphocytic-Dendritic-pDC|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

UGCG KCNK10 LRP5 FHIP1A

3.66e-0416094461f4cb4eb4313d8318aadbb99595a6cb7fd919f7
ToppCellCOVID_non-vent-Lymphocytic-Dendritic|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

UGCG KCNK10 LRP5 FHIP1A

3.66e-0416094434b4f710cfcb6ec370b8b074f3cbfe272f392cec
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKK1 KCNV2 LRP1B DNAH9

3.66e-0416094425c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellAdult-Immune-mast_cell|Adult / Lineage, Cell type, age group and donor

CCDC83 TMC2 P2RX1 BACE2

3.75e-0416194444f5c0256b3ce264a6c7b62740f32dcd45ee052d
ToppCelldroplet-Lung-30m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GPR174 UGCG CHSY1 ARAP2

3.75e-04161944cd4a736d0cec31477c6e8d3b07a04ede1559854b
ToppCelldroplet-Lung-30m-Hematologic-Lymphocytic_NK_ILC|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GPR174 UGCG CHSY1 ARAP2

3.75e-0416194428930ba576625b98cc15993d1499e9dc5edbb5a9
ToppCelldroplet-Lung-30m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-natural_killer|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GPR174 UGCG CHSY1 ARAP2

3.84e-04162944ccba6d8d644fe56060ad388ec3a062b7e3b9f086
ToppCellE16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PI4K2B MAN1A1 CLTC LRP1B

3.84e-041629448e0f03fcc25b2ea777e8478fbf771699cf93719c
ToppCellE16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PI4K2B MAN1A1 CLTC LRP1B

3.84e-04162944e0417f1242edf71934fe62bccc55c4678f7ff4ac
ToppCellTCGA-Uterus-Primary_Tumor-Uterine_Carcinoma-Uterine_Carcinosarcoma-3|TCGA-Uterus / Sample_Type by Project: Shred V9

CMIP SAT1 FRYL TBC1D9

3.93e-04163944d64dd39b077105c73e570ccef70f0e74a2c586ac
ToppCellcontrol-Plasmablast|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SLC6A9 MAN1A1 BACE2 TXNDC11

4.11e-0416594461063e0ce61bc92d5d1093be8279af03f650720b
ToppCelldroplet-Pancreas-Exocrine-24m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A9 P2RX1 GPC3 PAH

4.11e-04165944622aca1d49bd8c917b131e4f4959d9dba411d22b
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Syt6-Excitatory_NeuronSlc17a7-Slc17a6.Syt6-Nnat_(Deep_layer_pyramidal_cells--medial_cortex)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

IQCH GABRR3 DNTT

4.19e-0469943de297aa59c70f15c55cb9570439dc6d3fd6c182b
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Syt6|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

IQCH GABRR3 DNTT

4.19e-046994331f4fb56dfa5e3ad7c83e0770960c3617e4f66a7
ToppCell10x5'-Liver-Myeloid_Dendritic-pDC|Liver / Manually curated celltypes from each tissue

P2RX1 UGCG KCNK10 FHIP1A

4.21e-0416694424dfa9f3e0842f9ab8350bf6a52ae0d10f2a0c44
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC16A9 ASS1 PAH DNAH9

4.31e-041679443edb0570e583bb527165bcd8a4c25a042054043b
ToppCelldroplet-Pancreas-Exocrine-24m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A9 P2RX1 GPC3 PAH

4.31e-041679443c06894fc6177f3c204094719904da42f08b9af8
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC16A9 KCNJ15 ASS1 PAH

4.40e-04168944fa0d251693935116adf633d02b7ec4a295100865
DiseasePsychotic Disorders

SLC6A9 SAT1 TRPM2 PAH CRHR1

1.65e-05101925C0033975
Diseasenephrotic syndrome type 20 (implicated_via_orthology)

TBC1D8 TBC1D9

5.75e-054922DOID:0070357 (implicated_via_orthology)
DiseaseNonorganic psychosis

SLC6A9 SAT1 TRPM2 CRHR1

6.55e-0569924C0349204
Diseasehereditary spastic paraplegia 31 (implicated_via_orthology)

REEP1 REEP3

1.43e-046922DOID:0110782 (implicated_via_orthology)
DiseaseDisorder of amino acid metabolism

ASS1 PAH

2.66e-048922cv:C0002514
Diseaseautosomal dominant polycystic kidney disease (implicated_via_orthology)

IFT88 LRP5

8.54e-0414922DOID:898 (implicated_via_orthology)
Diseasecyclic adenosine monophosphate measurement

MAN1A1 ARAP2

1.27e-0317922EFO_0010473
DiseaseUnipolar Depression

SAT1 KCNK2 OAS2 GRIA2 CRHR1

1.32e-03259925C0041696
Diseasenicotine dependence symptom count, depressive symptom measurement

CORO2B SLC16A9 KCNK10

1.68e-0375923EFO_0007006, EFO_0009262
Diseasenose morphology measurement, mouth morphology measurement

KCNK10 DNA2

1.94e-0321922EFO_0007843, EFO_0007955
DiseaseDepressive disorder

ANKK1 SAT1 KCNK2 OAS2 CRHR1

2.14e-03289925C0011581
DiseaseAnhedonia

KCNK2 CRHR1

2.54e-0324922C0178417
Diseasecoronary artery calcification

P2RX1 IFT88 KCNK10 LRP6 UTP20 LRP1B

2.88e-03450926EFO_0004723

Protein segments in the cluster

PeptideGeneStartEntry
DIYLIDWIFTLYSKS

TBC1D12

661

O60347
WSEYIAGEYTLLLLV

CATSPERG

406

Q6ZRH7
EDDYLIKAVYDYWVR

EPC2

166

Q52LR7
YDDLAVLEKDLYWDA

BEST2

326

Q8NFU1
EWYYQIEILKLEIGG

BACE2

271

Q9Y5Z0
LWFSEDYKEYAFAII

ATP13A4

216

Q4VNC1
KYDVYSFAIVIWELL

ANKK1

206

Q8NFD2
YVEILKLLSDYDDWR

CMIP

456

Q8IY22
YLSIWTELQAYIKEF

CAP1

186

Q01518
IDDALLTKELYPYWI

ARAP2

1196

Q8WZ64
KELWLYIGINTFDYL

ABCD4

266

O14678
IWYYSTKVQLAELID

BPTF

491

Q12830
LVWLKEQGYDVIAYL

ASS1

21

P00966
LFLEKLSEKEYWEEY

CCDC83

126

Q8IWF9
WVLGEYSYLLDKETP

AP4E1

516

Q9UPM8
EEKTYYIELWDVGGS

RABL3

56

Q5HYI8
ALKSLWDYDFLIYDG

IQCH

261

Q86VS3
ALAIIYNLWFGYDVK

GGT3P

481

A6NGU5
GILADFKWINTLYLY

SLC16A9

361

Q7RTY1
NKLVYWVDLYLDYVG

LRP1B

381

Q9NZR2
VGLSIDYVENKLYWI

LRP1B

1736

Q9NZR2
EIDKYWREYILSLEE

GPC3

291

P51654
DDLFAYWEKLIYLLR

GARIN4

161

Q8IYT1
AIDYDPLDKFIYWVD

LRP5

981

O75197
GSDIEYLDFYKPVVW

KCNK2

276

O95069
DLKGALLSLIEYYQW

GRIA2

131

P42262
GWVYEGSKILVYSLE

FBXW8

406

Q8N3Y1
LLVSFDGFRWDYLYK

ENPP5

31

Q9UJA9
GYLYKWLDNILDSLD

FRYL

1131

O94915
DKVDGIYLLYLQDLW

KCNJ15

41

Q99712
GLTLDYEEQKLYWAD

LRP6

186

O75581
LWSEITELLYKDGRY

LRPPRC

556

P42704
KYIEGWTALESIYFV

KCNK10

256

P57789
EVYGSVAKVADYWLD

POLE

1001

Q07864
QKYDLYISIAGWLII

GPR174

131

Q9BXC1
KYALELLTIYAWEQG

OAS2

566

P29728
EYIEKLATIYWFTVE

PAH

316

P00439
QLFVEGYKDADYWLR

PI4K2A

261

Q9BTU6
FQLFVEGYKEAEYWL

PI4K2B

256

Q8TCG2
KEYEWVLIAGYIIVF

HCRTR2

51

O43614
RLSIYGIWFYDKEEC

DCP1B

106

Q8IZD4
IAVSTDYWLYLEEGV

CACNG5

26

Q9UF02
LWINYALYEELEAKD

CRNKL1

536

Q9BZJ0
EYGKALDISYLQYLW

FHIP1A

491

Q05DH4
YLKAVDVYLWVSSLF

GABRR3

326

A8MPY1
LGAYYIDTQFWEKAI

IFT88

626

Q13099
NILFSAGYDYKVLIW

CORO2B

151

Q9UQ03
DALYDVYLDVIDKWG

DNASE1L2

181

Q92874
DWIYDLGIKYSFTIE

CPB2

371

Q96IY4
LYEAYVEWKLKGEIS

FUT10

346

Q6P4F1
GYEVAKYDLIWICDS

UGCG

131

Q16739
IIVAWAIGKLYYDNE

CRHR1

271

P34998
EIYELEKLWTLRSYD

MALSU1

186

Q96EH3
LGDSFYEYLLKAWLM

MAN1A1

411

P33908
GLGDSFYEYLLKAWL

MAN1A2

396

O60476
WYAYLISLIVKTGFE

GJB7

121

Q6PEY0
VLYLSLWDALKYLGE

GLB1L2

391

Q8IW92
ELEFWKSRYEDLKYI

DNAH9

251

Q9NYC9
YLDFKIGEIWNEIYE

CFAP69

751

A5D8W1
DTWIIDKDFGYLILY

DNA2

106

P51530
LVYVIGWVFLYEKGY

P2RX1

41

P51575
IDGYYNVLWEKLDDY

RNF139

446

Q8WU17
EEEVETYFFEGLLKW

UTP20

41

O75691
ELLVWYGDCYEKFLD

PRDM14

361

Q9GZV8
IVYLLEKIDTDWYRG

SH3D19

521

Q5HYK7
NLWEKKGLLLYYDLV

DNTT

366

P04053
FLEELGYWGVRLKYT

KCNV2

181

Q8TDN2
DSWTGKVLYLEDFYV

SATL1

606

Q86VE3
YDPWIGKLLYLEDFF

SAT1

81

P21673
YELKIAFVAWLLSPY

REEP1

66

Q9H902
LDYLLEMLWEYLALT

DRG2

276

P55039
DQTVAWFPLYYELKI

REEP3

56

Q6NUK4
WEEYLEKFLTGKVAY

SULT1B1

156

O43704
HLWAELVFLYDKYEE

CLTC

1356

Q00610
EEILEWEFLTGKYLY

CHSY1

371

Q86X52
HLWAELVFLYDKYEE

CLTCL1

1356

P53675
LYAVYLLDWLSVFDK

CHST15

456

Q7LFX5
DYLEYWLILDYVSDI

CNGA1

191

P29973
DLQKGYYLVWLVLDY

CNGA2

166

Q16280
KILVFTEDGYFLRAW

NHLRC3

86

Q5JS37
KEFVTWDTLLYLYEN

TRPM2

511

O94759
LLYTKEEEAFWLLVA

TBC1D8

601

O95759
LLYAKEEEAFWLLVA

TBC1D9

611

Q6ZT07
GPWYYYETIDKELID

NDUFB5

166

O43674
EEYWRLYVLKLSDDI

SLC6A9

266

P48067
YYLWCLAGGDLEKEL

TBCK

326

Q8TEA7
EALVKLYYTLGVAWL

TTC23L

161

Q6PF05
AALWEYEVYKFKEIG

VPS41

426

P49754
EWHLETKIYVLDYLG

TXNDC11

281

Q6PKC3
FYVINYLELGKSWEE

ZNF277

261

Q9NRM2
VLWDFEGYIKYSALF

TMC2

306

Q8TDI7
LYEVFIEWGISAKVF

ZBED1

251

O96006
DLAVYELLKSYWLDN

SLC25A24

361

Q6NUK1
GLWLLYILFASLEAY

SLC8A2

901

Q9UPR5
LYSQKLYKLGWEEAL

NEB

2266

P20929