Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	actin cytoskeleton	FLNA FLNB SYNPO2 SHROOM3 MYLK ITSN1 CD2AP TMOD3 MYO3A ANLN GYS2 PRKCB MACF1 AKAP13 LRRC7 CGNL1	4.84e-07	576	128	16	GO:0015629
GeneOntologyCellularComponent	cell leading edge	MYLK RAPH1 ITSN1 CD2AP TMOD3 GRIN1 FAT1 PTPN13 APPL2 PTPRO MACF1 USH2A	5.92e-05	500	128	12	GO:0031252
GeneOntologyCellularComponent	cell cortex	FLNA FLNB SHROOM3 CD2AP AKAP12 ANLN GYS2 PRKCB MACF1 AKAP13	9.74e-05	371	128	10	GO:0005938
GeneOntologyCellularComponent	filopodium	RAPH1 NLGN1 ARL4C MYO3A FAT1 LRRC7	1.11e-04	123	128	6	GO:0030175
GeneOntologyCellularComponent	dendritic spine	EPHB2 DNAJB1 ITSN1 GRIN1 NLGN1 P2RX6 PTPRO LRRC7	1.25e-04	242	128	8	GO:0043197
GeneOntologyCellularComponent	neuron spine	EPHB2 DNAJB1 ITSN1 GRIN1 NLGN1 P2RX6 PTPRO LRRC7	1.43e-04	247	128	8	GO:0044309
GeneOntologyCellularComponent	cortical cytoskeleton	FLNA SHROOM3 ANLN GYS2 PRKCB AKAP13	1.44e-04	129	128	6	GO:0030863
GeneOntologyCellularComponent	cortical actin cytoskeleton	SHROOM3 ANLN GYS2 PRKCB AKAP13	2.69e-04	93	128	5	GO:0030864
GeneOntologyCellularComponent	anchoring junction	FLNA FLNB SYNPO2 SHROOM3 MYLK DSG3 TNC CD2AP TMOD3 AKAP12 FAT1 LRRC7 CAPN5 CGNL1 WNK3 ADGRL3	3.11e-04	976	128	16	GO:0070161
GeneOntologyCellularComponent	lamellipodium	MYLK RAPH1 ITSN1 TMOD3 FAT1 PTPN13 PTPRO	5.46e-04	230	128	7	GO:0030027
GeneOntologyCellularComponent	protein complex involved in cell-cell adhesion	NLGN1 IZUMO1	5.49e-04	6	128	2	GO:0098635
GeneOntologyCellularComponent	cell-cell junction	FLNA SHROOM3 MYLK DSG3 CD2AP TMOD3 FAT1 LRRC7 CGNL1 WNK3 ADGRL3	1.03e-03	591	128	11	GO:0005911
GeneOntologyCellularComponent	postsynaptic specialization membrane	GRIK4 GRIN1 NLGN1 P2RX6 PTPRO LRRC7	1.51e-03	201	128	6	GO:0099634
GeneOntologyCellularComponent	glutamatergic synapse	EPHB2 DNAJB1 FLNA ITSN1 GRIK4 GRIN1 NLGN1 TENM4 P2RX6 PTPRO PLXNC1 LRRC7 ADGRL3	1.53e-03	817	128	13	GO:0098978
GeneOntologyCellularComponent	filamentous actin	CD2AP TMOD3 MYO3A	1.62e-03	38	128	3	GO:0031941
GeneOntologyCellularComponent	actin-based cell projection	RAPH1 NLGN1 ARL4C MYO3A FAT1 LRRC7 USH2A	1.64e-03	278	128	7	GO:0098858
GeneOntologyCellularComponent	actin filament	FLNA CD2AP TMOD3 MYO3A AKAP13	2.06e-03	146	128	5	GO:0005884
HumanPheno	Accessory carpal bones	FLNA FLNB	6.32e-05	2	41	2	HP:0004232
HumanPheno	Bipartite calcaneus	FLNA FLNB	6.32e-05	2	41	2	HP:0008127
HumanPheno	Abnormality of the capitate bone	FLNA FLNB SMOC1	1.01e-04	12	41	3	HP:0004262
HumanPheno	Abnormality of the hamate bone	FLNA FLNB SMOC1	1.01e-04	12	41	3	HP:0004259
HumanPheno	Capitate-hamate fusion	FLNA FLNB SMOC1	1.01e-04	12	41	3	HP:0001241
Domain	DUF1908	MAST4 MAST1	2.64e-04	4	125	2	PF08926
Domain	MA_Ser/Thr_Kinase_dom	MAST4 MAST1	2.64e-04	4	125	2	IPR015022
Domain	MAST_pre-PK_dom	MAST4 MAST1	2.64e-04	4	125	2	IPR023142
Domain	-	MAST4 MAST1	2.64e-04	4	125	2	1.20.1480.20
Domain	Kinase-like_dom	EPHB2 MYLK RAPH1 WDR81 NEK4 MYO3A PTPN13 MAST4 MAST1 PRKCB MACF1 WNK3	2.84e-04	542	125	12	IPR011009
Domain	PDZ	SYNPO2 SHROOM3 PTPN13 MAST4 MAST1 LRRC7	3.74e-04	141	125	6	PF00595
Domain	RII_binding_1	AKAP12 AKAP13	4.39e-04	5	125	2	PF10522
Domain	RII_binding_1	AKAP12 AKAP13	4.39e-04	5	125	2	IPR018459
Domain	ACTININ_2	FLNA FLNB MACF1	4.70e-04	23	125	3	PS00020
Domain	ACTININ_1	FLNA FLNB MACF1	4.70e-04	23	125	3	PS00019
Domain	Actinin_actin-bd_CS	FLNA FLNB MACF1	4.70e-04	23	125	3	IPR001589
Domain	PDZ	SYNPO2 SHROOM3 PTPN13 MAST4 MAST1 LRRC7	4.84e-04	148	125	6	SM00228
Domain	-	EPHB2 FLNA FLNB MXRA5 MYLK EBF3 TNC IGSF10 SNED1 PTPRO PLXNC1 IZUMO1 USH2A	5.04e-04	663	125	13	2.60.40.10
Domain	-	SYNPO2 SHROOM3 PTPN13 MAST4 MAST1 LRRC7	5.19e-04	150	125	6	2.30.42.10
Domain	PDZ	SYNPO2 SHROOM3 PTPN13 MAST4 MAST1 LRRC7	5.38e-04	151	125	6	PS50106
Domain	PDZ	SYNPO2 SHROOM3 PTPN13 MAST4 MAST1 LRRC7	5.57e-04	152	125	6	IPR001478
Domain	fn3	EPHB2 MYLK TNC SNED1 PTPRO USH2A	7.78e-04	162	125	6	PF00041
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	DNAJB1 SHROOM3 RAPH1 CD2AP CBX4 NEK4 USP31 PTPN13 DENND1B MAST4 ANLN MACF1 AKAP13 BOD1L1 CEP152 CGNL1 PC WNK3 RASAL2	7.41e-10	861	132	19	36931259
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	FLNA FLNB COPB1 TNC ITSN1 TMOD3 DHX57 GRIN1 PGM1 USP31 CRACD TENM4 APPL2 UGP2 MAST1 PRKCB MACF1 LRRC7 CGNL1 ALDH1B1 PC RASAL2	2.30e-08	1431	132	22	37142655
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	UBR2 NLGN1 USP31 YEATS2 CRACD TENM4 MAST1 MACF1 BOD1L1 LRRC7 ADGRL3 SON	5.54e-08	407	132	12	12693553
Pubmed	Identification of proximal SUMO-dependent interactors using SUMO-ID.	FLNA NR2C2 MAGED1 LIN54 CD2AP TMOD3 ZNF280B CBX4 MCM10 YEATS2 ANLN PC	1.42e-07	444	132	12	34795231
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	DNAJB1 FLNA RAPH1 COPB1 POLDIP3 TMOD3 AKAP12 YEATS2 CRACD PTPN13 MACF1 BOD1L1 CGNL1 PC NUP153 SON	5.55e-07	934	132	16	33916271
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	RGPD2 FLNA FLNB NR2C2 RAPH1 ZGRF1 LIN54 CD2AP YEATS2 PTPN13 PC	6.25e-07	418	132	11	34709266
Pubmed	Large-scale proteomics and phosphoproteomics of urinary exosomes.	DNAJB1 FLNA FLNB MXRA5 TUT4 DSG3 CD2AP PM20D1 PGM1 FAT1 PTPN13 SLC12A1 APPL2 PTPRO UGP2 CAPN5	1.66e-06	1016	132	16	19056867
Pubmed	PEA15 regulates the DNA damage-induced cell cycle checkpoint and oncogene-directed transformation.	DNAJB1 PUS3 PGM1 SON	1.99e-06	24	132	4	24710276
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	AMD1 UBR2 FLNB SHROOM3 TUT4 MCM8 MYT1 CD2AP YEATS2 TSC22D1 PTPN13 DENND1B MAST1 MACF1 AKAP13 BOD1L1 MACROH2A2 LRRC7 AADAT	3.68e-06	1489	132	19	28611215
Pubmed	LncRNAs-directed PTEN enzymatic switch governs epithelial-mesenchymal transition.	SHROOM3 COPB1 CCDC168 IGSF10 SNED1 PTPN13 AKAP13	3.84e-06	168	132	7	30631154
Pubmed	Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.	FLNA FLNB RAPH1 TMOD3 YEATS2 CRACD ANLN CKAP2L BOD1L1 NUP153 SON	3.95e-06	506	132	11	30890647
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	RGPD2 SHROOM3 MAGED1 HECW1 EBF3 ITSN1 WDR81 GRIN1 AKAP12 PRKCB MACF1 LRRC7 WNK3 NUP153 RASAL2	4.10e-06	963	132	15	28671696
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	DNAJB1 FLNA TUT4 MAGED1 DIS3L CD2AP DHX57 MORC2 AKAP12 PTPN13 MACF1 AKAP13 SON	4.13e-06	724	132	13	36232890
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	SETD1A SYNPO2 SHROOM3 MAGED1 ITSN1 SLC12A1 AKAP13 ADGRL3 NUP153 SON	6.14e-06	430	132	10	35044719
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	SHROOM3 PUS3 COPB1 LIN54 MCM10 AKAP12 ARL4D ARL4C FAT1 PTPN13 CGNL1 PC RASAL2	8.79e-06	777	132	13	35844135
Pubmed	BOD1L mediates chromatin binding and non-canonical function of H3K4 methyltransferase SETD1A.	SETD1A BOD1L1	1.43e-05	2	132	2	38989615
Pubmed	Deletion of densin-180 results in abnormal behaviors associated with mental illness and reduces mGluR5 and DISC1 in the postsynaptic density fraction.	GRIN1 LRRC7	1.43e-05	2	132	2	22072671
Pubmed	Disruption of the Flnb gene in mice phenocopies the human disease spondylocarpotarsal synostosis syndrome.	FLNA FLNB	1.43e-05	2	132	2	17635842
Pubmed	TR4 promotes fatty acid synthesis in 3T3-L1 adipocytes by activation of pyruvate carboxylase expression.	NR2C2 PC	1.43e-05	2	132	2	25240193
Pubmed	Structural and functional aspects of filamins.	FLNA FLNB	1.43e-05	2	132	2	11336782
Pubmed	The variants at FLNA and FLNB contribute to the susceptibility of hypertension and stroke with differentially expressed mRNA.	FLNA FLNB	1.43e-05	2	132	2	33649519
Pubmed	Clues to CD2-associated protein involvement in cytokinesis.	CD2AP ANLN	1.43e-05	2	132	2	15800069
Pubmed	Disrupted surface cross-talk between NMDA and Ephrin-B2 receptors in anti-NMDA encephalitis.	EPHB2 GRIN1	1.43e-05	2	132	2	22544902
Pubmed	EphB receptors regulate dendritic spine development via intersectin, Cdc42 and N-WASP.	EPHB2 ITSN1	1.43e-05	2	132	2	12389031
Pubmed	Filamin depletion blocks endoplasmic spreading and destabilizes force-bearing adhesions.	FLNA FLNB	1.43e-05	2	132	2	21325628
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	DNAJB1 FLNB COPB1 CD2AP TMOD3 AKAP12 PTPN13 MACF1 BOD1L1 LRRC7 NUP153 RASAL2	1.74e-05	708	132	12	39231216
Pubmed	Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.	DNAJB1 FLNA FLNB RAPH1 COPB1 CRACD APPL2 MACF1 BOD1L1 MACROH2A2	2.18e-05	498	132	10	36634849
Pubmed	Myosin-X recruits lamellipodin to filopodia tips.	DNAJB1 MAGED1 RAPH1 UGP2 RASAL2	2.35e-05	89	132	5	36861887
Pubmed	Architectural niche organization by LHX2 is linked to hair follicle stem cell function.	FLNB TNC MACF1	4.18e-05	18	132	3	24012369
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	FLNA FLNB ITSN1 UTP23 YEATS2 FAT1 MACF1 SON	4.18e-05	332	132	8	37433992
Pubmed	Filamins as integrators of cell mechanics and signalling.	FLNA FLNB	4.28e-05	3	132	2	11252955
Pubmed	Opposing FlnA and FlnB interactions regulate RhoA activation in guiding dynamic actin stress fiber formation and cell spreading.	FLNA FLNB	4.28e-05	3	132	2	28175289
Pubmed	Ablation of NMDA receptors enhances the excitability of hippocampal CA3 neurons.	GRIK4 GRIN1	4.28e-05	3	132	2	19142228
Pubmed	Computational model explains high activity and rapid cycling of Rho GTPases within protein complexes.	COPB1 ITSN1	4.28e-05	3	132	2	17140284
Pubmed	The receptor tyrosine kinase EphB2 regulates NMDA-dependent synaptic function.	EPHB2 GRIN1	4.28e-05	3	132	2	11754836
Pubmed	Kinase-independent requirement of EphB2 receptors in hippocampal synaptic plasticity.	EPHB2 GRIN1	4.28e-05	3	132	2	11754835
Pubmed	GPIbα regulates platelet size by controlling the subcellular localization of filamin.	FLNA FLNB	4.28e-05	3	132	2	22174152
Pubmed	Filamin A and Filamin B are co-expressed within neurons during periods of neuronal migration and can physically interact.	FLNA FLNB	4.28e-05	3	132	2	12393796
Pubmed	Genomic structure and fine mapping of the two human filamin gene paralogues FLNB and FLNC and comparative analysis of the filamin gene family.	FLNA FLNB	4.28e-05	3	132	2	11153914
Pubmed	Sustained generation of neurons destined for neocortex with oxidative metabolic upregulation upon filamin abrogation.	FLNA FLNB	4.28e-05	3	132	2	38989458
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	DNAJB1 SETD1A FLNA RAPH1 CD2AP YEATS2 PTPN13 ANLN BOD1L1 PC	4.95e-05	549	132	10	38280479
Pubmed	CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI.	AKAP12 CRACD PTPN13 AKAP13 ALDH1B1	4.97e-05	104	132	5	31240132
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	DNAJB1 FLNA FLNB SHROOM3 RAPH1 CD2AP TMOD3 ANLN MACF1 LRRC7	6.28e-05	565	132	10	25468996
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	MAGED1 ITSN1 PTPN13 MACF1 LRRC7 NUP153 RASAL2	6.89e-05	263	132	7	34702444
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	MEAF6 FLNA NR2C2 POLDIP3 LIN54 CD2AP CBX4 YEATS2 ANLN BOD1L1 PC NUP153 SON	7.32e-05	954	132	13	36373674
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	FLNA FLNB CD2AP PGM1 AKAP12 ANLN MACF1 PC	7.37e-05	360	132	8	33111431
Pubmed	Hippocampal Lnx1-NMDAR multiprotein complex mediates initial social memory.	EPHB2 GRIN1	8.54e-05	4	132	2	31772302
Pubmed	The sarcomeric Z-disc component myopodin is a multiadapter protein that interacts with filamin and alpha-actinin.	FLNA SYNPO2	8.54e-05	4	132	2	20554076
Pubmed	The SH2-containing inositol polyphosphate 5-phosphatase, SHIP-2, binds filamin and regulates submembraneous actin.	FLNA FLNB	8.54e-05	4	132	2	11739414
Pubmed	Interaction of presenilins with the filamin family of actin-binding proteins.	FLNA FLNB	8.54e-05	4	132	2	9437013
Pubmed	Structural interaction and functional regulation of polycystin-2 by filamin.	FLNA FLNB	8.54e-05	4	132	2	22802962
Pubmed	ADP-ribosylation factor (ARF)-like 4, 6, and 7 represent a subgroup of the ARF family characterization by rapid nucleotide exchange and a nuclear localization signal.	ARL4D ARL4C	8.54e-05	4	132	2	10462049
Pubmed	Nephrin regulates lamellipodia formation by assembling a protein complex that includes Ship2, filamin and lamellipodin.	FLNA RAPH1	8.54e-05	4	132	2	22194892
Pubmed	Altered expression of regulators of the cortical chloride transporters NKCC1 and KCC2 in schizophrenia.	SLC12A1 WNK3	8.54e-05	4	132	2	20819979
Pubmed	Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome.	ITSN1 GRIN1 PLXNC1 MACF1 LRRC7 ADGRL3	1.11e-04	197	132	6	36604605
Pubmed	Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation.	FLNA FLNB SYNPO2 TNC AKAP12 FAT1 CAPN5	1.14e-04	285	132	7	21423176
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	RGPD2 FLNA FLNB TUT4 MAGED1 HECW1 GRIN1 TENM4 PRKCB MACF1 LRRC7 ALDH1B1 PC ADGRL3	1.14e-04	1139	132	14	36417873
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	TUT4 MAGED1 POLDIP3 ITSN1 TMOD3 MCM10 NEK4 YEATS2 ANLN AKAP13 BOD1L1	1.17e-04	733	132	11	34672954
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	FLNB MXRA5 ITSN1 GRIN1 PGM1 IGSF10 PRKCB UTP20 AKAP13 BOD1L1 LRRC7	1.21e-04	736	132	11	29676528
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	FLNA FLNB DHX57 LRRC31 UTP20 AKAP13	1.27e-04	202	132	6	33005030
Pubmed	Increasing the Receptor Tyrosine Kinase EphB2 Prevents Amyloid-β-induced Depletion of Cell Surface Glutamate Receptors by a Mechanism That Requires the PDZ-binding Motif of EphB2 and Neuronal Activity.	EPHB2 GRIN1	1.42e-04	5	132	2	26589795
Pubmed	NMDA receptor GluN2B (GluR epsilon 2/NR2B) subunit is crucial for channel function, postsynaptic macromolecular organization, and actin cytoskeleton at hippocampal CA3 synapses.	GRIK4 GRIN1	1.42e-04	5	132	2	19726645
Pubmed	HIV infection of T cells: actin-in and actin-out.	FLNA FLNB	1.42e-04	5	132	2	19366992
Pubmed	Nephrocystin-conserved domains involved in targeting to epithelial cell-cell junctions, interaction with filamins, and establishing cell polarity.	FLNA FLNB	1.42e-04	5	132	2	12006559
Pubmed	EphrinB phosphorylation and reverse signaling: regulation by Src kinases and PTP-BL phosphatase.	EPHB2 PTPN13	1.42e-04	5	132	2	11983165
Pubmed	Filamin B deficiency in mice results in skeletal malformations and impaired microvascular development.	FLNA FLNB	1.42e-04	5	132	2	17360453
Pubmed	Pharmacological targeting of actin-dependent dynamin oligomerization ameliorates chronic kidney disease in diverse animal models.	CD2AP PRKCB	1.42e-04	5	132	2	25962121
Pubmed	Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1.	RGPD2 FLNA FLNB COPB1 CD2AP TMOD3	1.78e-04	215	132	6	35973513
Pubmed	Characterising the dynamics of placental glycogen stores in the mouse.	PGM1 GYS2 UGP2	1.82e-04	29	132	3	32798765
Pubmed	Binding of USP4 to cortactin enhances cell migration in HCT116 human colon cancer cells.	DNAJB1 FLNA CD2AP TMOD3 PC	1.83e-04	137	132	5	37039823
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	AMD1 DNAJB1 FLNB CD2AP CBX4 MCM10 MORC2 ANLN MACROH2A2 CEP152	1.85e-04	645	132	10	25281560
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	SETD1A FLNA FLNB COPB1 POLDIP3 DHX57 MCM10 ANLN MACF1 UTP20 AKAP13 MACROH2A2 ALDH1B1 RASAL2 SON	1.99e-04	1353	132	15	29467282
Pubmed	Protein kinase C isoenzymes differentially regulate the differentiation-dependent expression of adhesion molecules in human epidermal keratinocytes.	DSG3 PRKCB	2.12e-04	6	132	2	18637128
Pubmed	Vector-capping: a simple method for preparing a high-quality full-length cDNA library.	FLNA FLNB	2.12e-04	6	132	2	16106752
Pubmed	Neto1 is an auxiliary subunit of native synaptic kainate receptors.	GRIK4 GRIN1	2.12e-04	6	132	2	21734292
Pubmed	WNK3 kinase is a positive regulator of NKCC2 and NCC, renal cation-Cl- cotransporters required for normal blood pressure homeostasis.	SLC12A1 WNK3	2.12e-04	6	132	2	16275913
Pubmed	ASB2 targets filamins A and B to proteasomal degradation.	FLNA FLNB	2.12e-04	6	132	2	18799729
Pubmed	Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.	EPHB2 DNAJB1 FLNA FLNB MAGED1 COPB1 POLDIP3 LIN54 CD2AP PGM1 AKAP12 ANLN UGP2 PC SON	2.22e-04	1367	132	15	32687490
Pubmed	HIV-1 Vpr degrades the HLTF DNA translocase in T cells and macrophages.	FLNA FLNB ANLN	2.45e-04	32	132	3	27114546
Pubmed	Charting the landscape of tandem BRCT domain-mediated protein interactions.	DNAJB1 FLNA FLNB DIS3L DHX57 ZNF280B PGM1 C2orf42 ALDH1B1 USH2A	2.50e-04	670	132	10	22990118
Pubmed	Comparative analysis of virus-host interactomes with a mammalian high-throughput protein complementation assay based on Gaussia princeps luciferase.	UBR2 DNAJB1 FLNA AP1M2 GALNT5	2.61e-04	148	132	5	22898364
Pubmed	Comprehensive identification of phosphorylation sites in postsynaptic density preparations.	RGPD2 TNC ITSN1 PRKCB MACF1 LRRC7	2.62e-04	231	132	6	16452087
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	FLNA FLNB ZGRF1 MACF1 CGNL1 PC	2.81e-04	234	132	6	36243803
Pubmed	Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.	UBR2 HECW1 DHX57 MYO3A TENM4 C2orf42 LRRC7 CEP152 HEPHL1 NUP153 RASAL2	2.87e-04	814	132	11	23251661
Pubmed	Human ISG15 conjugation targets both IFN-induced and constitutively expressed proteins functioning in diverse cellular pathways.	DNAJB1 FLNA FLNB TMOD3 CBX4	2.96e-04	152	132	5	16009940
Pubmed	Cloning and expression analysis of the mouse stroma marker Snep encoding a novel nidogen domain protein.	TNC SNED1	2.97e-04	7	132	2	15162516
Pubmed	The Z-disc proteins myotilin and FATZ-1 interact with each other and are connected to the sarcolemma via muscle-specific filamins.	FLNA FLNB	2.97e-04	7	132	2	16076904
Pubmed	NRAGE: a potential rheostat during branching morphogenesis.	NR2C2 MAGED1	2.97e-04	7	132	2	19268530
Pubmed	Protein Kinase 2β Is Expressed in Neural Crest-Derived Urinary Pacemaker Cells and Required for Pyeloureteric Contraction.	PLXNC1 PRKCB	2.97e-04	7	132	2	29436516
Pubmed	Protein interactome reveals converging molecular pathways among autism disorders.	FLNA FLNB TUT4 MAGED1 HECW1 RBM45 TNC ITSN1 ADAMTSL2	3.00e-04	560	132	9	21653829
Pubmed	Study of FOXO1-interacting proteins using TurboID-based proximity labeling technology.	SYNPO2 SHROOM3 GLTP CD2AP TMOD3 AKAP12	3.44e-04	243	132	6	36964488
Pubmed	A ubiquitin-based effector-to-inhibitor switch coordinates early brain, craniofacial, and skin development.	SHROOM3 PLXNC1 BOD1L1 KCTD18	3.46e-04	87	132	4	37495603
Pubmed	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.	TNC ITSN1 GRIN1 PRKCB MACF1 LRRC7 ADGRL3	3.76e-04	347	132	7	17114649
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	RGPD2 FLNA FLNB MYLK RAPH1 PCDHGB5 PYROXD1 ITSN1 LIN54 DHX57 RNF17 UGP2 MACF1 BOD1L1 ALDH1B1	3.91e-04	1442	132	15	35575683
Pubmed	MYH9-dependent polarization of ATG9B promotes colorectal cancer metastasis by accelerating focal adhesion assembly.	FLNA FLNB	3.94e-04	8	132	2	34131310
Pubmed	MEKK4 signaling regulates filamin expression and neuronal migration.	FLNA FLNB	3.94e-04	8	132	2	17145501
Pubmed	[The use of discrete characters in discriminant analysis for diagnosis of pulmonary tuberculosis and for classification of patients differing in treatment efficiency based on polymorphisms at nine codominant loci-HP, GC, TF, PI, PGM1, GLO1, C3, ACP1 and ESD].	GC PGM1	3.94e-04	8	132	2	12942785
Pubmed	Filamin B mutations cause chondrocyte defects in skeletal development.	FLNA FLNB	3.94e-04	8	132	2	17510210
Pubmed	The Arl4 family of small G proteins can recruit the cytohesin Arf6 exchange factors to the plasma membrane.	ARL4D ARL4C	3.94e-04	8	132	2	17398095
Pubmed	SMOC1 is a tenascin-C interacting protein over-expressed in brain tumors.	TNC SMOC1	3.94e-04	8	132	2	21349332
Interaction	ACTC1 interactions	FLNA FLNB NR2C2 MYLK RAPH1 RBM45 CD2AP TMOD3 GC GRIN1 NEK4 YEATS2 CRACD DMRT2 ANLN CKAP2L BOD1L1 NUP153 SON	9.28e-08	694	129	19	int:ACTC1
Interaction	YWHAG interactions	DNAJB1 FLNA SYNPO2 SHROOM3 RAPH1 COPB1 CD2AP CBX4 NEK4 USP31 CRACD PTPN13 DENND1B MAST4 ANLN PRKCB MACF1 AKAP13 BOD1L1 CGNL1 ALDH1B1 RASAL2 SON	3.99e-06	1248	129	23	int:YWHAG
Interaction	KCTD13 interactions	FLNA FLNB MAGED1 COPB1 TNC ITSN1 TMOD3 DHX57 GRIN1 PGM1 USP31 CRACD TENM4 APPL2 UGP2 MAST1 PRKCB MACF1 LRRC7 CGNL1 ALDH1B1 PC RASAL2	2.39e-05	1394	129	23	int:KCTD13
Interaction	RHOB interactions	EPHB2 UBR2 SHROOM3 RAPH1 ITSN1 UTP23 MCM10 AKAP12 USP31 FAT1 PTPN13 ANLN MACF1 UTP20 AKAP13 ALDH1B1 RASAL2	2.61e-05	840	129	17	int:RHOB
Interaction	TENM1 interactions	TNC NEK4 TENM4 MACF1	2.91e-05	28	129	4	int:TENM1
Interaction	SFN interactions	DNAJB1 SETD1A SHROOM3 CD2AP CBX4 NEK4 USP31 PTPN13 DENND1B MAST4 ANLN MACF1 AKAP13 CGNL1 RASAL2	3.72e-05	692	129	15	int:SFN
Interaction	YWHAE interactions	UBR2 FLNA SHROOM3 TMOD3 CBX4 MCM10 NEK4 USP31 CRACD PTPN13 DENND1B MAST4 APPL2 ANLN MAST1 PRKCB MACF1 AKAP13 CGNL1 ALDH1B1 RASAL2	4.70e-05	1256	129	21	int:YWHAE
Interaction	ZYX interactions	SHROOM3 ITSN1 CD2AP NEK4 CRACD UGP2 MACF1 AKAP13 CEP152 WNK3	5.19e-05	329	129	10	int:ZYX
Cytoband	4q21.1	SHROOM3 MEPE FAM47E	1.68e-04	37	132	3	4q21.1
GeneFamily	PDZ domain containing	SYNPO2 SHROOM3 PTPN13 MAST4 MAST1 LRRC7	7.58e-05	152	84	6	1220
GeneFamily	Fibronectin type III domain containing	EPHB2 MYLK TNC SNED1 PTPRO USH2A	1.01e-04	160	84	6	555
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	RAPH1 ITSN1 APPL2 ANLN AKAP13 RASAL2	3.95e-04	206	84	6	682
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	HECW1 ITSN1 CAPN5	6.18e-04	36	84	3	823
Coexpression	LAKE_ADULT_KIDNEY_C27_VASCULAR_SMOOTH_MUSCLE_CELLS_AND_PERICYTES	DNAJB1 FLNA SYNPO2 MYLK AKAP12 AKAP13 ANKRD36 ADGRL3 RASAL2	9.56e-08	155	132	9	M39246
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HGABA	TUT4 RAPH1 EBF3 MYT1 LIN54 CBX4 NLGN1 ANKRD36B ARL4C MAST4 PTPRO PLXNC1 MAST1 PRKCB BOD1L1 LRRC7 ANKRD36 WNK3 ADGRL3 RASAL2	7.06e-07	1106	132	20	M39071
CoexpressionAtlas	dev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_1000	FLNA MAGED1 MCM8 TNC TMOD3 SMOC1 IGSF10 FAT1 TENM4 PLXNC1 ANLN RXFP2 CKAP2L PRKCB ALDH1B1 WNK3 ADGRL3	6.37e-06	793	129	17	gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_1000
CoexpressionAtlas	DevelopingKidney_e15.5_Peripheral blastema_emap-27731_k-means-cluster#3_top-relative-expression-ranked_1000	EBF3 MCM10 AKAP12 NEK4 SNED1 PLXNC1 ANLN CGNL1 GALNT5 ADGRL3	1.86e-05	307	129	10	gudmap_developingKidney_e15.5_Peripheral blastema_1000_k3
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_MedNas_2500_K1	EPHB2 TUT4 MCM8 LIN54 NLGN1 MCM10 SORCS1 NEK4 CRACD ARL4C DENND1B PTPRO CKAP2L MACF1 BOD1L1 WNK3 PHF21B RASAL2 ADAMTSL2	2.20e-05	1060	129	19	facebase_RNAseq_e10.5_Emin_MedNas_2500_K1
CoexpressionAtlas	dev gonad_e11.5_F_GonMes_Sma_top-relative-expression-ranked_1000	DNAJB1 FLNA SHROOM3 TNC CCDC80 CBX4 SMOC1 PTPN13 TENM4 DENND1B PLXNC1 RXFP2 PRKCB ALDH1B1 WNK3 ADGRL3	6.55e-05	858	129	16	gudmap_dev gonad_e11.5_F_GonMes_Sma_1000
CoexpressionAtlas	dev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_1000	FLNA TUT4 MAGED1 RAPH1 TNC SMOC1 IGSF10 FAT1 TENM4 PLXNC1 ANLN RXFP2 ALDH1B1 WNK3 ADGRL3	6.73e-05	768	129	15	gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_1000
CoexpressionAtlas	dev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_1000	FLNA TUT4 MAGED1 MYLK CCDC80 SMOC1 IGSF10 FAT1 TENM4 PLXNC1 ANLN RXFP2 ALDH1B1 WNK3 ADGRL3	7.23e-05	773	129	15	gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_1000
CoexpressionAtlas	dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k-means-cluster#4_top-relative-expression-ranked_200	SMOC1 PLXNC1 WNK3	7.59e-05	14	129	3	gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k4_200
CoexpressionAtlas	dev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_1000	FLNA MYLK TNC ZGRF1 TMOD3 SMOC1 IGSF10 TENM4 PLXNC1 ANLN RXFP2 CKAP2L ALDH1B1 WNK3 ADGRL3	7.66e-05	777	129	15	gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_1000
CoexpressionAtlas	dev gonad_e12.5_F_VasAssMesen_MafB_top-relative-expression-ranked_1000	FLNA TUT4 CCDC80 SMOC1 IGSF10 YEATS2 PTPN13 TENM4 DENND1B PLXNC1 RXFP2 PRKCB ALDH1B1 WNK3 ADGRL3	8.35e-05	783	129	15	gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000	EPHB2 AMD1 TUT4 MYT1 GRIK4 NLGN1 MCM10 NEK4 CRACD ARL4C PLXNC1 CKAP2L MAST1 UTP20 BOD1L1 PHF21B RASAL2	1.04e-04	989	129	17	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_MedNas_2500	EPHB2 TUT4 MCM8 LIN54 TMEM154 NLGN1 MCM10 SORCS1 NEK4 CRACD ARL4C DENND1B PTPRO RXFP2 CKAP2L MACF1 BOD1L1 WNK3 PHF21B RASAL2 ADAMTSL2	1.21e-04	1414	129	21	facebase_RNAseq_e10.5_Emin_MedNas_2500
CoexpressionAtlas	dev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_1000	MRC1 FLNA SHROOM3 TNC CCDC80 SMOC1 PTPN13 TENM4 DENND1B PLXNC1 ANLN PRKCB ALDH1B1 WNK3 ADGRL3	1.52e-04	827	129	15	gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_1000
CoexpressionAtlas	dev gonad_e11.5_F_GonadVasMes_Flk_k-means-cluster#2_top-relative-expression-ranked_1000	SMOC1 TSC22D1 PTPN13 PLXNC1 WNK3	1.61e-04	84	129	5	gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_k2_1000
CoexpressionAtlas	dev gonad_e11.5_M_GonMes_Sma_top-relative-expression-ranked_1000	DNAJB1 SHROOM3 TNC ZGRF1 CCDC80 SMOC1 IGSF10 PTPN13 TENM4 DENND1B PLXNC1 PRKCB ALDH1B1 WNK3 ADGRL3	2.03e-04	849	129	15	gudmap_dev gonad_e11.5_M_GonMes_Sma_1000
CoexpressionAtlas	DevelopingKidney_e13.5_podocyte cells_emap-27773_top-relative-expression-ranked_100	RBM45 EBF3 NEK4 DMRT2 PTPRO	2.11e-04	89	129	5	gudmap_developingKidney_e13.5_podocyte cells_100
ToppCell	LA-13._Vascular_Smooth_Muscle\|LA / Chamber and Cluster_Paper	FLNA FLNB SYNPO2 SHROOM3 MYLK TNC TSC22D1 MACF1 ADGRL3 RASAL2	2.56e-10	188	132	10	34e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCell	LA-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	FLNA FLNB SYNPO2 SHROOM3 MYLK TNC TSC22D1 MACF1 ADGRL3 RASAL2	2.70e-10	189	132	10	6b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	MXRA5 MYLK PCDHGB5 TNC CCDC80 AKAP12 IGSF10 SNED1 MACF1 LRRC7	4.04e-10	197	132	10	fdb92985f7df0c280b87d3e43c2394e70786a2c7
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FLNB GLTP DSG3 TNC FAT1 PTPN13 ANLN SERPINB11 GALNT5	7.85e-09	197	132	9	fb272c9c60ee3d980e528044dc567b4925a23da6
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FLNB GLTP DSG3 TNC FAT1 PTPN13 ANLN SERPINB11 GALNT5	7.85e-09	197	132	9	61c0d78b29dc4ad8a84172cbfcdab03f31351d0e
ToppCell	ILEUM-non-inflamed-(8)_Fibroblasts\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	FLNB SYNPO2 MXRA5 MYLK TNC CCDC80 AKAP12 CAPN5 ADGRL3	8.58e-09	199	132	9	d9d7f36b4b5592b7855448730044c90997b55499
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	MXRA5 MYLK PCDHGB5 TNC ITSN1 CCDC80 AKAP12 IGSF10 MACF1	8.58e-09	199	132	9	e1849505b92820a219c5a2c35492bdd55579fb48
ToppCell	ILEUM-non-inflamed-(8)_Fibroblast\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	FLNB SYNPO2 MXRA5 MYLK TNC CCDC80 AKAP12 TSC22D1 ADGRL3	8.58e-09	199	132	9	6a0df9a2f30480043f9c1d7fbdede17eb0910cac
ToppCell	LPS-IL1RA+antiTNF\|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SHROOM3 CCDC80 NLGN1 IGSF10 PTPN13 AKAP13 CGNL1 GALNT5	5.95e-08	177	132	8	b7fee75de7e96924af488a5baa2334711889ae7c
ToppCell	E16.5-samps-Mesenchymal-Myofibroblast\|E16.5-samps / Age Group, Lineage, Cell class and subclass	EPHB2 SYNPO2 MYLK TNC NLGN1 SORCS1 TENM4 ADAMTSL2	8.73e-08	186	132	8	e044b3428b7eacfdc72d0f57cdabaa1de04c74cd
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FLNA SYNPO2 MYLK TNC SMOC1 AKAP12 LRRC7 ADGRL3	1.03e-07	190	132	8	2e88e366d377d74deb53a4ea870973ce5c6532e8
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FLNA SYNPO2 MYLK TNC SMOC1 AKAP12 LRRC7 ADGRL3	1.03e-07	190	132	8	0028f886c789ba238c031eae5d96acaed4af8c25
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	SYNPO2 MCM8 ZGRF1 MCM10 ANLN LRRC7 CEP152 ADAMTSL2	1.03e-07	190	132	8	e83fa8b711aa79a1767818474f1c193b674b1c31
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	SYNPO2 HECW1 MCM8 ZGRF1 MCM10 PLXNC1 ANLN ADAMTSL2	1.16e-07	193	132	8	516ea2c12bdc7a5dc676159d627e36f6abe13ef0
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	EPHB2 SHROOM3 RAPH1 CD2AP NLGN1 ARL4C FAT1 AKAP13	1.21e-07	194	132	8	46070fbb0ee0eb9e1801c43b73a15707471056dc
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	EPHB2 SHROOM3 RAPH1 CD2AP NLGN1 ARL4C FAT1 AKAP13	1.21e-07	194	132	8	abacb6a8d7a9003f2f6c2be0305507f1c1c50347
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	EPHB2 EBF3 CCDC80 NLGN1 AKAP12 IGSF10 LRRC7 ADGRL3	1.21e-07	194	132	8	439d3f17c1f4736122b330e98add9292c7036a8e
ToppCell	facs-Liver-Non-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MRC1 FLNB CCDC80 AKAP12 PLXNC1 MACF1 DNASE1L3 RASAL2	1.36e-07	197	132	8	deefb492b5f0e6014144bd465c4a6ae4206e8739
ToppCell	facs-Liver-Non-hepatocytes-3m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MRC1 FLNB CCDC80 AKAP12 PLXNC1 MACF1 DNASE1L3 RASAL2	1.36e-07	197	132	8	a6aaa6faea348291023f0bc4b0f83fbc67d91da6
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FLNB GLTP DSG3 TNC FAT1 ANLN SERPINB11 GALNT5	1.36e-07	197	132	8	dcabea5c50c133c9a4e294e447462d0393174ea7
ToppCell	E18.5-Mesenchymal\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLNA MAGED1 MYLK TNC CCDC80 AKAP12 TSC22D1 MACF1	1.41e-07	198	132	8	a16aa41eab2e297e56de43c22c355df0f79315da
ToppCell	facs-Liver-Non-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MRC1 FLNB CCDC80 AKAP12 PLXNC1 MACF1 DNASE1L3 RASAL2	1.41e-07	198	132	8	f0f1816a0ed3ae8207442602f5cbe4de0382e4b3
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SHROOM3 NLGN1 STX19 PTPN13 GALNT5 AADAT WNK3	1.46e-07	133	132	7	5bf5e654653e2c340891f51e3f2a30441b7b6b2b
ToppCell	ILEUM-non-inflamed-(8)_Smooth_muscle_cells\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	FLNA SYNPO2 SHROOM3 MYLK AKAP12 FAT1 ALDH1B1 ADGRL3	1.47e-07	199	132	8	3368c0a90a47c4dcdfe70be3192550df0744e508
ToppCell	3'-Pediatric_IBD-SmallIntestine-Mesenchymal\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SYNPO2 MXRA5 MYLK TNC CCDC80 AKAP12 TSC22D1 ADGRL3	1.47e-07	199	132	8	50abd20eb461927fde0ec5caae501d7f2277cf78
ToppCell	3'-Child04-06-SmallIntestine-Mesenchymal\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SYNPO2 MXRA5 MYLK TNC CCDC80 AKAP12 TSC22D1 ADGRL3	1.47e-07	199	132	8	a843bdfcb58bec5e2a94a5ec9d5b8c5e4aef15d2
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SYNPO2 ZGRF1 MCM10 CRACD ANLN RXFP2 CKAP2L	8.01e-07	171	132	7	b0373ed8283ee1792b6a490bff93906546978593
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SYNPO2 ZGRF1 MCM10 CRACD ANLN RXFP2 CKAP2L	8.01e-07	171	132	7	b92963f9f247d2e5e2e6c51c6dbf70e527cd2f55
ToppCell	RA-13._Vascular_Smooth_Muscle\|RA / Chamber and Cluster_Paper	FLNA FLNB SYNPO2 MYLK TNC ADGRL3 RASAL2	1.26e-06	183	132	7	818fd886e0188091310825f9145fa53328f2c979
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	FLNA SYNPO2 MYLK PLXNC1 UGP2 LRRC7 ADAMTSL2	1.26e-06	183	132	7	e84539978ab4de42e19186aed00f24bb50cbc21f
ToppCell	COVID-19-Heart-Fib_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SYNPO2 EBF3 TNC CCDC80 SNED1 TENM4 ADGRL3	1.36e-06	185	132	7	8f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MXRA5 GLTP DSG3 TNC ARL4D PTPN13 SERPINB11	1.36e-06	185	132	7	e0172e0ab0f1d7151a3c3c63bb7c84d6bda92035
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SYNPO2 TNC SNED1 FAT1 TENM4 PHF21B ADAMTSL2	1.46e-06	187	132	7	c104fbfef2d0bef64077ac721edf2379fd59d547
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FLNA SYNPO2 MYLK HECW1 PLXNC1 LRRC7 ADAMTSL2	1.51e-06	188	132	7	3004e961d214919e08c7cd5f10c3de5cf85b35a3
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_myocytic\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FLNA SYNPO2 MYLK HECW1 PLXNC1 LRRC7 ADAMTSL2	1.56e-06	189	132	7	f75cebd4c3e54e297557449ba67ccc8d1a2a14f5
ToppCell	E18.5-samps-Mesenchymal\|E18.5-samps / Age Group, Lineage, Cell class and subclass	FLNA MAGED1 MYLK TNC AKAP12 TSC22D1 MACF1	1.56e-06	189	132	7	0c18d3de4720759cf802eefb4d0ddde2a9246a1a
ToppCell	IPF-Epithelial-Basal\|IPF / Disease state, Lineage and Cell class	DSG3 TNC USP31 FAT1 PTPN13 MAST4 GALNT5	1.62e-06	190	132	7	ea19e9ce954f2dfde97388db9695325cd92ab88f
ToppCell	PND10\|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLNA MYLK TNC MACF1 CGNL1 ADGRL3 SON	1.62e-06	190	132	7	d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Neuronal-Immature_INs\|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.	MYT1 SMOC1 ARL4D CRACD ARL4C MYO3A PHF21B	1.62e-06	190	132	7	842760bfe0a52e67bad800efa7d99448a4a23ebb
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	EPHB2 EBF3 CCDC80 NLGN1 AKAP12 IGSF10 LRRC7	1.74e-06	192	132	7	8d56e360ebc624ca4cd7f0af4f3cc599c244f134
ToppCell	PND14-Mesenchymal-Mesenchymal_structural\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYLK CCDC80 AKAP12 IGSF10 SNED1 MACF1 ADAMTSL2	1.74e-06	192	132	7	25492568f9cbe097b7bb1db50d8b817c80ea87d7
ToppCell	PND14-Mesenchymal-Mesenchymal_structural-Fibroblastic\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYLK CCDC80 AKAP12 IGSF10 SNED1 MACF1 ADAMTSL2	1.74e-06	192	132	7	de9c1536d5aee86f9c62acbc54ca8fa581c00f17
ToppCell	IPF-Epithelial-Basal\|World / Disease state, Lineage and Cell class	DSG3 TNC USP31 FAT1 PTPN13 MAST4 GALNT5	1.74e-06	192	132	7	9b91e0b162e6f3ce86dd15cc33c2e745d069581f
ToppCell	10x5'v1-week_17-19-Mesenchymal_osteo-stroma-early_osteoblast\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	MXRA5 TNC CCDC80 MEPE FAT1 TENM4 ADAMTSL2	1.80e-06	193	132	7	5e46a9f65e85aca78f825fdef88a95b97eec8743
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLNA SYNPO2 MYLK TNC AKAP12 LRRC7 ALDH1B1	1.80e-06	193	132	7	5578f7cb3ec68c9a38cc5304b618b81283024d5e
ToppCell	Control-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	FLNA MYLK TNC GRIK4 TSC22D1 MACF1 ADAMTSL2	1.80e-06	193	132	7	5896242f713ae5fd1a4ebb63827f15d7279dced2
ToppCell	RV-10._Endothelium_II\|World / Chamber and Cluster_Paper	FLNB RAPH1 CD2AP SMOC1 SNED1 CGNL1 DNASE1L3	1.80e-06	193	132	7	2531266bc57339d4e2b22a88817008e32b8c1598
ToppCell	nucseq-Mesenchymal-Myocytic-Myocytic_2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SYNPO2 MXRA5 MYLK HECW1 CRACD FAT1 TENM4	1.80e-06	193	132	7	5de87fc94a6e58899ef4124cf4887ed3ff96163a
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM1_(8)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	SYNPO2 MEPE SNED1 FAT1 PRKCB LRRC7 ADAMTSL2	1.80e-06	193	132	7	e2b455387d1de7812305200a2041a0f4759a6f54
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SYNPO2 TNC GRIK4 SNED1 CRACD PRKCB ADAMTSL2	1.92e-06	195	132	7	d9a5c75d31c6e8bb1e1ab7fd115ac5deb5fb1c8d
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FLNA SYNPO2 MYLK CRACD ADGRL3 RASAL2 ADAMTSL2	1.92e-06	195	132	7	49c99553629cdd83ee56a2e508d5bc8d34b8507b
ToppCell	PND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYLK CCDC80 AKAP12 IGSF10 SNED1 MACF1 ADAMTSL2	1.92e-06	195	132	7	3a0cad69cfc150a27a0666f612f5294c817197d7
ToppCell	PND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYLK CCDC80 AKAP12 IGSF10 SNED1 MACF1 ADAMTSL2	1.92e-06	195	132	7	2b8ee7990267bb52b7e6ae03f509ffebf8908122
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FLNA SYNPO2 MYLK CRACD ADGRL3 RASAL2 ADAMTSL2	1.92e-06	195	132	7	dd281a249854800f737dc22e0f375f66dfb5cf5f
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SYNPO2 TNC SMOC1 AKAP12 CRACD PRKCB ADAMTSL2	1.92e-06	195	132	7	44d7bef5f59c2c2bad1392ee6aabdaa5d7f531d9
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SYNPO2 TNC GRIK4 SNED1 CRACD PRKCB ADAMTSL2	1.99e-06	196	132	7	a12dd986df65c36f248cf10815c3b8b6238613b0
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SHROOM3 CD2AP NLGN1 FAT1 PTPN13 DENND1B MAST4	1.99e-06	196	132	7	c7136b1c83bcf907eec3b02b151fa061298b6672
ToppCell	E17.5-Mesenchymal-mesenchymal_fibroblast-mesenchymal_progenitor_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	MAGED1 MYLK TNC TSC22D1 TENM4 MACF1 MACROH2A2	1.99e-06	196	132	7	028a06ed92f1c058dcbeacd335625bf529e87a7b
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SYNPO2 TNC GRIK4 SNED1 CRACD PRKCB ADAMTSL2	1.99e-06	196	132	7	3e6803587d8566fd08cb8b290be3b6461743d79c
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	MYLK GRIK4 NLGN1 IGSF10 MAST4 PRKCB MACF1	2.06e-06	197	132	7	31a1852911bda38543916585fda34255fd62a134
ToppCell	COVID-19-Fibroblasts-Intermediate_pathological_FB\|COVID-19 / group, cell type (main and fine annotations)	MXRA5 MYLK TNC CCDC80 SNED1 CRACD TENM4	2.06e-06	197	132	7	f1c8936986123a3151140c374fcd62d6705c530b
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SYNPO2 TNC GRIK4 SNED1 CRACD PRKCB ADAMTSL2	2.06e-06	197	132	7	6d027119a5f7ca2aac1b10837e43f9a2bb54db85
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DNAJB1 MYLK CCDC80 AKAP12 ARL4D TSC22D1 TENM4	2.06e-06	197	132	7	5f6fce382f273e789ffbb75b63e9b4e87519918e
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SYNPO2 TNC GRIK4 SNED1 CRACD PRKCB ADAMTSL2	2.06e-06	197	132	7	b349f8e96d61a4c296af64711e11fc44459a9413
ToppCell	356C-Fibroblasts-Fibroblast-K_(Pericytes)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	FLNA SYNPO2 MYLK TNC TSC22D1 ALDH1B1 ADGRL3	2.06e-06	197	132	7	71367bebc23d0e81f60f780d6b0ab3a1783ac014
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SYNPO2 TNC CCDC80 AKAP12 SNED1 RASAL2 ADAMTSL2	2.06e-06	197	132	7	9b480f9c799a244bfee64487abd8a1bf07c9a3a2
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	MYLK GRIK4 NLGN1 IGSF10 MAST4 PRKCB MACF1	2.06e-06	197	132	7	0034bae02ee7fcfea520d453ca3c842ab6963b12
ToppCell	356C-Fibroblasts-Fibroblast-K_(Pericytes)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	FLNA SYNPO2 MYLK TNC TSC22D1 ALDH1B1 ADGRL3	2.06e-06	197	132	7	0f9836554ace3f9d155ebafdd719aa26466ca44e
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SYNPO2 TNC GRIK4 SNED1 CRACD PRKCB ADAMTSL2	2.06e-06	197	132	7	c2e390653d5dee7e731c1840cfdab41987dede9b
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FLNB GLTP DSG3 TNC FAT1 ANLN GALNT5	2.13e-06	198	132	7	e06d41a7254a09e037ec404be2d8c352d5cbd7f4
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SYNPO2 TNC CCDC80 AKAP12 SNED1 RASAL2 ADAMTSL2	2.13e-06	198	132	7	a860246bcea847249a78fd2e86ed8e04371060db
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EPHB2 DNAJB1 EBF3 CCDC80 AKAP12 TENM4 CGNL1	2.13e-06	198	132	7	cfe2d52b19a1b4c2c2076fa1d5a69baf21a49623
ToppCell	normal_Lung-Fibroblasts-Smooth_muscle_cells\|Fibroblasts / Location, Cell class and cell subclass	FLNA SYNPO2 MYLK TNC MYO3A TSC22D1 ADGRL3	2.20e-06	199	132	7	d65847ceb68a560798df3f73e6f838e7c3e38a1c
ToppCell	10x5'v1-week_14-16-Mesenchymal_adipo-stroma\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	MXRA5 EBF3 TNC CCDC80 TSC22D1 PTPN13 TENM4	2.20e-06	199	132	7	9b2262edbdec89166d895ab97527e0ee5f9b6010
ToppCell	10x5'v1-week_14-16-Mesenchymal_adipo\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	MXRA5 EBF3 TNC CCDC80 TSC22D1 PTPN13 TENM4	2.20e-06	199	132	7	251b3643dcd8f4645b17101bd716e66f12a20e88
ToppCell	Tracheal-NucSeq-Stromal-Peri/Epineurial_\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SYNPO2 NLGN1 AKAP12 SNED1 PTPN13 LRRC7 ADAMTSL2	2.20e-06	199	132	7	3835452e4848d7f7dd8651c17b746b271ef39688
ToppCell	3'-Child09-12-SmallIntestine-Mesenchymal\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SYNPO2 MXRA5 TNC CCDC80 AKAP12 TSC22D1 ADGRL3	2.20e-06	199	132	7	d2f6d04045e11d81c979949d0f5c2f7380f33400
ToppCell	ILEUM-inflamed-(8)_Fibroblasts\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	FLNB SYNPO2 MXRA5 MYLK TNC AKAP12 ADGRL3	2.20e-06	199	132	7	3a3e2bb21cd0293622b1a975263e918d9ba24265
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HECW1 MYT1 SMOC1 TSC22D1 LRRC7 ANKRD36 WNK3	2.20e-06	199	132	7	19a97e27a4758e794ce7246d295e112b47931a48
ToppCell	Tracheal-NucSeq-Stromal-Peri/Epineurial_-NAF_epineurial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SYNPO2 NLGN1 AKAP12 SNED1 PTPN13 LRRC7 ADAMTSL2	2.20e-06	199	132	7	9c2db0bb94cba71a3cc1827844da090e213e0258
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	MYLK PCDHGB5 TNC CCDC80 AKAP12 IGSF10 MACF1	2.20e-06	199	132	7	30d3e8c0681ec11f86dd38c5f48d21187a1b4f90
ToppCell	10x5'v1-week_14-16-Mesenchymal_adipo-stroma-adipo-CAR\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	MXRA5 EBF3 TNC CCDC80 TSC22D1 PTPN13 TENM4	2.20e-06	199	132	7	117f4f43b6c06dda553799b1063e827bce697370
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	MYLK PCDHGB5 TNC CCDC80 AKAP12 IGSF10 MACF1	2.28e-06	200	132	7	9b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	MYLK TNC ITSN1 CCDC80 AKAP12 IGSF10 MACF1	2.28e-06	200	132	7	b79628fd1386aa9a3b0e9fa81def0bc100c3c073
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	MYLK TNC ITSN1 CCDC80 AKAP12 IGSF10 MACF1	2.28e-06	200	132	7	50ca6550998e461ef26dd670351060bd940765a8
ToppCell	Control_saline-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|Control_saline / Treatment groups by lineage, cell group, cell type	SYNPO2 MYLK TNC CCDC80 AKAP12 SORCS1 FAT1	2.28e-06	200	132	7	a799fc7bb83ad0524362cb5010df949741fb7bf3
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Diff_MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	MYLK TNC ITSN1 CCDC80 AKAP12 IGSF10 MACF1	2.28e-06	200	132	7	3bdba9612cd7c612b76aa9abecc4a6529aabfc1c
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	FLNA SYNPO2 MYLK TNC AKAP12 SORCS1 FAT1	2.28e-06	200	132	7	09537dc25f8b8b4654a7c183827ee1522a41a4e0
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	MYLK PCDHGB5 TNC CCDC80 AKAP12 IGSF10 MACF1	2.28e-06	200	132	7	44a68bacdb3d5bf563bd35952176995850933a81
ToppCell	LPS_only-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_only / Treatment groups by lineage, cell group, cell type	MYLK PCDHGB5 TNC ITSN1 CCDC80 AKAP12 MACF1	2.28e-06	200	132	7	a7ef7022b8efcaedb7319b0b43d8c4e99d788fe2
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	MYLK PCDHGB5 TNC CCDC80 AKAP12 IGSF10 MACF1	2.28e-06	200	132	7	dc61016c61729f69649cfb21f6264e685ce83dea
ToppCell	Control_saline-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|Control_saline / Treatment groups by lineage, cell group, cell type	MYLK PCDHGB5 TNC CCDC80 AKAP12 IGSF10 MACF1	2.28e-06	200	132	7	bd8cf33502adea320e91ca2af14e1911d88ad374
ToppCell	LPS-antiTNF-Endothelial-Epi-like\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MRS2 ZGRF1 CBX4 STX19 UTP20 ADAMTSL2	4.55e-06	144	132	6	75b16adfbe84f69376e6566d531ba7919d5c5192
ToppCell	3'_v3-Lung-Lymphocytic_T_CD4-T_CD4/CD8\|Lung / Manually curated celltypes from each tissue	TUT4 ANKRD36C ANKRD36B GYS2 MACF1 ANKRD36	5.98e-06	151	132	6	999c11d19b61d6b130ad5e623afa83cbdfe13cdd
ToppCell	368C-Myeloid-Dendritic-cDC1\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	FLNB DHX57 CAPN5 PLGLB1 DNASE1L3 ADAMTSL2	9.26e-06	163	132	6	299ac2463b7f58eee419d822a2a2d64b973d87e9
ToppCell	10x5'-Liver-Hematopoietic_progenitors\|Liver / Manually curated celltypes from each tissue	MCM8 RAPH1 MEIKIN CRACD ANLN CKAP2L	1.03e-05	166	132	6	ae967570248cf86ca3ddf55e33bcbb3e4e3684bc
ToppCell	10x5'-Liver-Hematopoietic_progenitors-Cycling_pre-Myeloid-2\|Liver / Manually curated celltypes from each tissue	MCM8 RAPH1 MEIKIN CRACD ANLN CKAP2L	1.03e-05	166	132	6	a176e87aa6eec81d1fb79a028f759182d11b567d
ToppCell	LPS_only-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NLGN1 MEPE CNTD1 PTPN13 GALNT5	1.10e-05	98	132	5	ffe21b3681fdeaf4a8447bd2b13772d03cdd45aa
ToppCell	facs-Liver-Non-hepatocytes-3m-Epithelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNB GC P2RX6 UGP2 AADAT PC	1.26e-05	172	132	6	feaaf8ca7983d04a59ed0a7b3fb0e6d4b3a055f2
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SYNPO2 RAPH1 CCDC80 MCM10 SNED1 P2RX6	1.26e-05	172	132	6	1ef243bce63d841c25e4b74d029d1377f84bcc3d
Drug	LY 294002; Down 200; 10uM; MCF7; HT_HG-U133A_EA	AMD1 DNAJB1 ITSN1 CBX4 MCM10 AKAP12 DENND1B UTP20 ALDH1B1	1.41e-06	190	129	9	1016_DN
Disease	myofibrillar myopathy 5 (implicated_via_orthology)	FLNA FLNB	5.59e-05	3	128	2	DOID:0080096 (implicated_via_orthology)
Disease	distal muscular dystrophy 4 (implicated_via_orthology)	FLNA FLNB	5.59e-05	3	128	2	DOID:0111190 (implicated_via_orthology)
Disease	NEPHROTIC SYNDROME, STEROID-RESISTANT, AUTOSOMAL RECESSIVE	CD2AP PTPRO ANLN	2.97e-04	30	128	3	C1868672
Disease	bullous pemphigoid	FLNB TNC MAST4	4.32e-04	34	128	3	EFO_0007187
Disease	Inherited focal segmental glomerulosclerosis	CD2AP ANLN	8.21e-04	10	128	2	cv:CN327126
Disease	Focal segmental glomerulosclerosis	CD2AP ANLN	8.21e-04	10	128	2	cv:C0017668
Disease	empathy measurement	SHROOM3 MYLK TENM4 OR1A1 AKAP13	8.95e-04	170	128	5	EFO_0009183
Disease	Hereditary Nephrotic Syndromes, Autosomal Dominant	CD2AP ANLN	1.00e-03	11	128	2	cv:CN043612
Disease	lifestyle measurement, depressive symptom measurement	DIS3L MYT1 NLGN1 USP31	1.15e-03	105	128	4	EFO_0007006, EFO_0010724
Disease	Familial idiopathic steroid-resistant nephrotic syndrome	CD2AP ANLN	1.41e-03	13	128	2	cv:C4273714
Disease	Liver Cirrhosis, Experimental	FLNA GC SMOC1 TSC22D1 FAT1 PTPRO PRKCB ALDH1B1 AADAT PC	2.05e-03	774	128	10	C0023893
Disease	Schizoaffective disorder-bipolar type	MYT1 UTP23	2.15e-03	16	128	2	EFO_0009965
Disease	Spondyloepiphyseal Dysplasia	FLNA ADAMTSL2	2.15e-03	16	128	2	C0038015
Disease	Spondyloepiphyseal Dysplasia Tarda, X-Linked	FLNA ADAMTSL2	2.15e-03	16	128	2	C3541456
Disease	Schwartz-Jampel Syndrome, Type 1	FLNA ADAMTSL2	2.15e-03	16	128	2	C4551479
Disease	Schwartz-Jampel Syndrome	FLNA ADAMTSL2	2.15e-03	16	128	2	C0036391
Disease	Melnick-Needles Syndrome	FLNA ADAMTSL2	2.15e-03	16	128	2	C0025237
Disease	thyroxine measurement, triiodothyronine measurement	EPHB2 CCDC80	2.43e-03	17	128	2	EFO_0005130, EFO_0008392
Disease	Van Buchem disease	FLNA ADAMTSL2	2.43e-03	17	128	2	C0432272
Disease	Malignant neoplasm of breast	FLNA FLNB RAPH1 AKAP12 SORCS1 MACF1 UTP20 BOD1L1 LRRC7 GALNT5 DNASE1L3 RASAL2	2.52e-03	1074	128	12	C0006142
Disease	osteochondrodysplasia (is_implicated_in)	FLNA FLNB	3.04e-03	19	128	2	DOID:2256 (is_implicated_in)
Disease	Osteochondrodysplasias	FLNA ADAMTSL2	3.04e-03	19	128	2	C0029422
Disease	Dyschondroplasias	FLNA ADAMTSL2	3.04e-03	19	128	2	C0013366
Disease	Multiple Epiphyseal Dysplasia	FLNA ADAMTSL2	3.37e-03	20	128	2	C0026760
Disease	chemokine (C-C motif) ligand 27 measurement	NEK4 USP31 LRRC7	3.53e-03	70	128	3	EFO_0008082
Disease	triacylglycerol 54:6 measurement	NLGN1 PRKCB	4.07e-03	22	128	2	EFO_0010424
Disease	intellectual disability (implicated_via_orthology)	ITSN1 ZNF280B BOD1L1	4.29e-03	75	128	3	DOID:1059 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
VNTQGPSLFSVTKKQ	PLGLB1	26	Q02325
FVGVTSNSKPVVSNI	ZNF280B	46	Q86YH2
TSFVQKVSGKSLPER	C2orf42	206	Q9NWW7
FPFKTAVITVENGKT	AADAT	46	Q8N5Z0
TFIQFKKPIVVSVNG	CDY2A	376	Q9Y6F7
QGTLEIPSESVKSKQ	CEP152	1596	O94986
TVPTIGFNTEKIKLS	ARL4C	41	P56559
FKKQSVANGVEISVP	AP1M2	301	Q9Y6Q5
FVQSVPTKGFNTEKI	ARL4D	46	P49703
AKTEPFTQGKVVGQT	AKAP12	1101	Q02952
QDAVSKKTFPTVNPT	ALDH1B1	46	P30837
VVTPNGLNVKKFSAV	GYS2	276	P54840
FPKQTAAQVTLKAIS	MACROH2A2	321	Q9P0M6
KKTVNGHTFSSIPVV	AKAP13	1786	Q12802
SPVITAAINKEFSNK	ADGRL3	766	Q9HAR2
SGTVSSQKQPAEKAT	ANKRD36	576	A6QL64
SGTVSSQKQPAEKAT	ANKRD36B	286	Q8N2N9
GTVSPQKQSAQKVIF	ANKRD36B	321	Q8N2N9
GTVSPQKQSAQKVIF	ANKRD36B	661	Q8N2N9
SAVQKGTSTPEYNVK	CAPN5	551	O15484
NVSETASGSVTQPKK	CD2AP	196	Q9Y5K6
TKITFPKEGDQTSNN	DNAJB1	216	P25685
KISVITIFGPVNNST	CCDC80	656	Q76M96
TVKTQAYQDQKPGTS	PGM1	6	P36871
TKPIKVFIAQSRSSG	RBM45	96	Q8IUH3
AVFSGNTSPKVAVVN	RAPH1	1091	Q70E73
PGLTSTSQIEKFQEK	NR2C2	506	P49116
KGAIQIPTVTFSSEK	PM20D1	56	Q6GTS8
GTVSSQKQPAEKATS	ANKRD36C	611	Q5JPF3
NSKIAFKIVSQEPAG	DSG3	191	P32926
LFVEKPGSAQISTKQ	FAT1	3696	Q14517
SFAKQLGQPVVSKTL	MYLK	126	Q15746
IFAKPINSKAVTGQT	LIN54	246	Q6MZP7
FKAQNATTKVGPNAT	MAGED1	146	Q9Y5V3
SKTTGKRTSEQTPQF	MCM8	41	Q9UJA3
AAPTFQPQTEKTKQS	MEPE	16	Q9NQ76
EVKAQAGSFPVKNLT	LRRC7	1181	Q96NW7
SVTVKNSAAPIFKSI	HECW1	176	Q76N89
KHQGVSKTQSLPVTE	ANLN	476	Q9NQW6
IKSPTNTVTVQGLKA	EPHB2	486	P29323
VKQPAKFTVDTISAG	FLNB	271	O75369
SIEPQKVSTLGKSNV	PLXNC1	666	O60486
IKNGDSQSKPFATVV	NEK4	281	P51957
SKLNKVTQLTGFSDP	COPB1	711	P53618
EGETKPQTSTVNKFL	LRRC31	11	Q6UY01
SVAPVFTVTKFDKQG	MRS2	81	Q9HD23
TNPTKLSITENGEFK	RASAL2	1121	Q9UJF2
VDSPKNFNIAGTVVK	ADAMTSL2	271	Q86TH1
SKAVAIEKAPQFSNV	MEIKIN	181	A0A087WXM9
SQGTKVPEEKTTNTV	PRKCB	311	P05771
TFGVILKKVTPQSVN	MCM10	296	Q7L590
KNSVPVTSAFPTAKQ	NLGN1	681	Q8N2Q7
QLQGEVPFKIISSSK	PCDHGB5	381	Q9Y5G0
LKSGNKVAVTTTPFE	MAST1	1041	Q9Y2H9
PSQISKTDKSFQGTT	MACF1	3131	Q9UPN3
VIQFGKSAKRTPEST	MORC2	81	Q9Y6X9
PKSLFAVNKTQTSVT	PTPRO	726	Q16827
QIKVKNSASVTVSPA	KCTD18	286	Q6PI47
TELQEGATKQATTPK	BOD1L1	926	Q8NFC6
GTEVKPLQFTNSKLF	IGSF10	1881	Q6WRI0
DIVKKQSTQFSGGPT	CARD6	426	Q9BX69
SVVPKSNSVFDFQKA	DNASE1L3	246	Q13609
FVAKQVGTKLSVNEP	DMRT2	526	Q9Y5R5
KISVKTFPSASNTQA	CGNL1	521	Q0VF96
QSGTTNKPNKFTVET	FLNA	1366	P21333
KQTTAQGAPKTSFIA	GALNT5	161	Q7Z7M9
VQVKSPEGKFQKTST	DHX57	1226	Q6P158
VVTFPSKEEVQSQGK	DIS3L	346	Q8TF46
KLSKENVSVSVQPGS	CRACD	1121	Q6ZU35
TKLQKAQSFDVASVP	ITSN1	196	Q15811
KPGKFVTTLFVNQSS	AMD1	276	P17707
TKEAFGEQPLQLTTK	CBX4	351	O00257
QAVTPITSFGKKQES	APPL2	396	Q8NEU8
VFTPIKADISGNITK	GLTP	41	Q9NZD2
VPQGKNVITGKSFTE	HEPHL1	41	Q6MZM0
KSGNKVSITTTPFEN	MAST4	1216	O15021
SVQGVKPQKAASSTS	MEAF6	146	Q9HAF1
SGAAEQTQVPKEKAT	IZUMO1	331	Q8IYV9
PISQIHKISGQFTTK	CCDC168	2401	Q8NDH2
ANVISAVKQKSAFAP	EBF3	551	Q9H4W6
SKQPSVFVKSTEEGI	GRIK4	696	Q16099
FQLTSPEVSQTDKGK	DENND1B	686	Q6P3S1
TPSQLQGEKFTSVKE	CNTD1	236	Q8N815
PQFSIITKLKGVSVT	P2RX6	71	O15547
SGASVTTQPTEFKIK	POLDIP3	406	Q9BY77
FTDSNQSKTKKPGIS	PTPN13	1296	Q12923
FSTVFQVPSTKGVLK	OR1A1	221	Q9P1Q5
KKGNTTLNSFVIPSE	MRC1	341	P22897
TQVYLGPSKKTSVSN	FAM47E	181	Q6ZV65
ENVGAFKKVSIVPTQ	USH2A	41	O75445
FPKLQANISTGVSKI	UTP20	631	O75691
SPKTIAFVKAVESGQ	UTP23	151	Q9BRU9
VKPSVIKQTSAFVEG	PUS3	391	Q9BZE2
ANVTPTKGSSNTEFK	RGPD2	886	P0DJD1
GKTKSAFSSLQNIPE	SHROOM3	656	Q8TF72
NQIGFVPEKTFSSLK	RXFP2	291	Q8WXD0
FFIGTVIPSNNEKKS	SLC12A1	341	Q13621
KKKSGFQITSVTPAQ	TSC22D1	106	Q15714
ETVKSPFQLSEGKNV	SERPINB11	196	Q96P15
QTVPTGGKALSEKFQ	SETD1A	191	O15047
SPVNTFQTVLITDGK	SNED1	166	Q8TER0
FLNKTAPKTQADVTT	CKAP2L	431	Q8IYA6
FQPQKDVATASPKTI	RNF17	376	Q9BXT8
VQNKTPVCSGSVTDK	SMOC1	151	Q9H4F8
TVPLVKLGSSFTKVQ	UGP2	426	Q16851
NPSKGTVVSSIKIAQ	SYNPO2	796	Q9UMS6
PTFQKATVVSVKNPS	PHF21B	96	Q96EK2
VTASPVIKAVTNFKQ	PYROXD1	41	Q8WU10
VKKSEVENGPSSVVT	STX19	116	Q8N4C7
SKPSVNSFISAQKET	THAP5	281	Q7Z6K1
RIFAEKGPQKSSTIT	TNC	1866	P24821
KFPSGTFEQVSQLVK	GC	51	P02774
ETFSQIPDGILNKKT	ZNF627	81	Q7L945
QQAPKTKKFASSGSV	TENM4	2551	Q6N022
AGVTQTPKFQVLKTG	TRBV6-1	21	A0A0K0K1D8
KQQEPVTSTSLVFGK	NUP153	1106	P49790
GSKEETAFQAVIPKQ	ZGRF1	911	Q86YA3
NKVTIPSTFAAVTIK	TMEM154	41	Q6P9G4
NTTGKEQLVTKDPAS	USP31	1286	Q70CQ4
SLPFVTTKNKEVNAT	SORCS1	896	Q8WY21
FPNSPVKAEKATISQ	TUT4	101	Q5TAX3
ELQQIGKKIPSSFTS	TUT4	176	Q5TAX3
HVVTFTFTQKISKPG	UBR2	946	Q8IWV8
KVTPSSKIVGDLAQF	PC	906	P11498
KSQVTLTKEFPVSSG	SON	2166	P18583
VTFSPAKLTNSQAKV	WDR81	246	Q562E7
SSVSKAVGPKQVVTQ	YEATS2	681	Q9ULM3
TLTKAQVTAAGPQKS	YEATS2	716	Q9ULM3
AGVTQTPKFQVLKTG	TRBV6-5	21	A0A0K0K1A5
RQKNQTSKSTTGPFD	TMOD3	51	Q9NYL9
VTSGIKPASFNKVTD	WNK3	361	Q9BYP7
SLGPANQTTSVKKEE	LEUTX	76	A8MZ59
STQPAEKDTVTIGKN	MXRA5	576	Q9NR99
FISAPNNKGSVSVVK	MYO3A	1151	Q8NEV4
APKIQTSETSPKAFQ	MYT1	601	Q01538
AEKVLQFDPGTKNVT	GRIN1	191	Q05586