Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	guanyl-nucleotide exchange factor activity	DOCK2 RGL3 DOCK7 ARHGEF12 ARHGEF2 ARHGEF11	1.59e-04	231	70	6	GO:0005085
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	DOCK2 ARHGAP6 RGL3 DOCK7 ARHGEF12 ARHGEF2 ARHGEF11 ARHGAP21	3.88e-04	507	70	8	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	DOCK2 ARHGAP6 RGL3 DOCK7 ARHGEF12 ARHGEF2 ARHGEF11 ARHGAP21	3.88e-04	507	70	8	GO:0030695
Domain	RGS-like	ARHGEF12 ARHGEF11	4.14e-05	3	70	2	PF09128
Domain	RGS-like_dom	ARHGEF12 ARHGEF11	4.14e-05	3	70	2	IPR015212
Domain	PH	OSBP ANLN ARHGEF12 OSBP2 ARHGEF2 ARHGEF11 ARHGAP21	8.08e-05	278	70	7	SM00233
Domain	PH_DOMAIN	OSBP ANLN ARHGEF12 OSBP2 ARHGEF2 ARHGEF11 ARHGAP21	8.26e-05	279	70	7	PS50003
Domain	PH_domain	OSBP ANLN ARHGEF12 OSBP2 ARHGEF2 ARHGEF11 ARHGAP21	8.45e-05	280	70	7	IPR001849
Domain	Bromodomain_CS	SMARCA4 TAF1 CREBBP	1.23e-04	26	70	3	IPR018359
Domain	BROMODOMAIN_1	SMARCA4 TAF1 CREBBP	3.58e-04	37	70	3	PS00633
Domain	Bromodomain	SMARCA4 TAF1 CREBBP	3.87e-04	38	70	3	PF00439
Domain	GDS_CDC24_CS	ARHGEF12 ARHGEF2 ARHGEF11	4.18e-04	39	70	3	IPR001331
Domain	BROMODOMAIN_2	SMARCA4 TAF1 CREBBP	4.85e-04	41	70	3	PS50014
Domain	BROMO	SMARCA4 TAF1 CREBBP	5.21e-04	42	70	3	SM00297
Domain	Bromodomain	SMARCA4 TAF1 CREBBP	5.21e-04	42	70	3	IPR001487
Domain	-	SMARCA4 TAF1 CREBBP	5.21e-04	42	70	3	1.20.920.10
Domain	-	OSBP ANLN ARHGEF12 OSBP2 ARHGEF2 ARHGEF11 ARHGAP21	6.44e-04	391	70	7	2.30.29.30
Domain	DOCK_C	DOCK2 DOCK7	7.45e-04	11	70	2	IPR010703
Domain	DHR-1_domain	DOCK2 DOCK7	7.45e-04	11	70	2	IPR027007
Domain	DHR_2	DOCK2 DOCK7	7.45e-04	11	70	2	PS51651
Domain	DHR_1	DOCK2 DOCK7	7.45e-04	11	70	2	PS51650
Domain	DOCK-C2	DOCK2 DOCK7	7.45e-04	11	70	2	PF14429
Domain	DHR-2	DOCK2 DOCK7	7.45e-04	11	70	2	IPR027357
Domain	DHR-2	DOCK2 DOCK7	7.45e-04	11	70	2	PF06920
Domain	DOCK	DOCK2 DOCK7	7.45e-04	11	70	2	IPR026791
Domain	Oxysterol-bd	OSBP OSBP2	8.92e-04	12	70	2	IPR000648
Domain	Oxysterol-bd_CS	OSBP OSBP2	8.92e-04	12	70	2	IPR018494
Domain	Oxysterol_BP	OSBP OSBP2	8.92e-04	12	70	2	PF01237
Domain	OSBP	OSBP OSBP2	8.92e-04	12	70	2	PS01013
Domain	PH_dom-like	OSBP ANLN ARHGEF12 OSBP2 ARHGEF2 ARHGEF11 ARHGAP21	1.06e-03	426	70	7	IPR011993
Domain	PH	OSBP ANLN OSBP2 ARHGEF2 ARHGAP21	1.68e-03	229	70	5	PF00169
Domain	DH_1	ARHGEF12 ARHGEF2 ARHGEF11	1.70e-03	63	70	3	PS00741
Domain	RhoGEF	ARHGEF12 ARHGEF2 ARHGEF11	2.12e-03	68	70	3	SM00325
Domain	RhoGEF	ARHGEF12 ARHGEF2 ARHGEF11	2.31e-03	70	70	3	PF00621
Domain	DH_2	ARHGEF12 ARHGEF2 ARHGEF11	2.31e-03	70	70	3	PS50010
Domain	DH-domain	ARHGEF12 ARHGEF2 ARHGEF11	2.40e-03	71	70	3	IPR000219
Domain	-	ARHGEF12 ARHGEF2 ARHGEF11	2.40e-03	71	70	3	1.20.900.10
Domain	Arm	KPNA7 CTNND1	6.00e-03	31	70	2	PF00514
Domain	SNF2_N	SMARCA4 CHD3	6.39e-03	32	70	2	IPR000330
Domain	SNF2_N	SMARCA4 CHD3	6.39e-03	32	70	2	PF00176
Pathway	REACTOME_RHOA_GTPASE_CYCLE	DOCK2 ARHGAP6 ANLN ARHGEF12 ARHGEF2 ARHGEF11 ARHGAP21	1.08e-06	142	54	7	MM15576
Pathway	REACTOME_RHOA_GTPASE_CYCLE	DOCK2 ARHGAP6 ANLN ARHGEF12 ARHGEF2 ARHGEF11 ARHGAP21	1.50e-06	149	54	7	M41805
Pathway	REACTOME_RHOB_GTPASE_CYCLE	ANLN ARHGEF12 ARHGEF2 ARHGEF11 ARHGAP21	6.37e-06	69	54	5	MM15596
Pathway	REACTOME_RHOB_GTPASE_CYCLE	ANLN ARHGEF12 ARHGEF2 ARHGEF11 ARHGAP21	6.84e-06	70	54	5	M41806
Pathway	REACTOME_VIRAL_INFECTION_PATHWAYS	ANO4 DOCK2 KPNA7 GALNT1 NUP107 HLA-F PSMC3 LARP1 RELA CHD3 TAF1 EIF2AK2 CREBBP	2.23e-05	888	54	13	M48034
Pathway	PID_RHOA_REG_PATHWAY	ARHGAP6 ARHGEF12 ARHGEF2 ARHGEF11	2.78e-05	46	54	4	M68
Pathway	REACTOME_RHO_GTPASE_CYCLE	DOCK2 ARHGAP6 SLC4A7 ANLN DOCK7 ARHGEF12 ARHGEF2 ARHGEF11 ARHGAP21	3.89e-05	439	54	9	MM15595
Pathway	REACTOME_INFECTIOUS_DISEASE	ANO4 DOCK2 KPNA7 GALNT1 NUP107 HLA-F PSMC3 LARP1 RELA CHD3 TAF1 CTNND1 EIF2AK2 CREBBP	3.96e-05	1081	54	14	M27548
Pathway	REACTOME_RHO_GTPASE_CYCLE	DOCK2 ARHGAP6 SLC4A7 ANLN DOCK7 ARHGEF12 ARHGEF2 ARHGEF11 ARHGAP21	4.71e-05	450	54	9	M27078
Pathway	REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA	MFAP1 WBP11 NUP107 GPATCH1 LENG1 STEEP1 SNRNP70	8.43e-05	277	54	7	MM15414
Pathway	REACTOME_METABOLISM_OF_RNA	MFAP1 WBP11 NUP107 GPATCH1 LENG1 STEEP1 PSMC3 PNO1 SNRNP70 SMG6	9.38e-05	612	54	10	MM15547
Pathway	REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA	MFAP1 WBP11 NUP107 GPATCH1 LENG1 STEEP1 SNRNP70	9.64e-05	283	54	7	M13087
Pathway	REACTOME_MRNA_SPLICING	MFAP1 WBP11 GPATCH1 LENG1 STEEP1 SNRNP70	1.14e-04	201	54	6	MM15411
Pathway	REACTOME_RHOC_GTPASE_CYCLE	ANLN ARHGEF12 ARHGEF11 ARHGAP21	1.46e-04	70	54	4	MM15597
Pathway	REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3	DOCK2 ARHGAP6 SLC4A7 NUP107 ANLN DOCK7 ARHGEF12 ARHGEF2 ARHGEF11 ARHGAP21	1.52e-04	649	54	10	MM15690
Pathway	REACTOME_MRNA_SPLICING	MFAP1 WBP11 GPATCH1 LENG1 STEEP1 SNRNP70	1.52e-04	212	54	6	M14033
Pathway	REACTOME_RHOC_GTPASE_CYCLE	ANLN ARHGEF12 ARHGEF11 ARHGAP21	1.81e-04	74	54	4	M41807
Pathway	REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING	ARHGEF12 RELA ARHGEF2 ARHGEF11	3.09e-04	85	54	4	MM14746
Pathway	REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3	DOCK2 ARHGAP6 SLC4A7 NUP107 ANLN DOCK7 ARHGEF12 ARHGEF2 ARHGEF11 ARHGAP21	3.52e-04	720	54	10	M41838
Pathway	REACTOME_METABOLISM_OF_RNA	MFAP1 WBP11 NUP107 GPATCH1 LENG1 STEEP1 PSMC3 PNO1 SNRNP70 SMG6	3.68e-04	724	54	10	M16843
Pathway	REACTOME_SARS_COV_INFECTIONS	ANO4 GALNT1 NUP107 HLA-F LARP1 RELA CHD3 CREBBP	3.94e-04	471	54	8	M39009
Pathway	REACTOME_REGULATION_OF_NFE2L2_GENE_EXPRESSION	RELA CREBBP	3.97e-04	8	54	2	M48024
Pathway	REACTOME_CDC42_GTPASE_CYCLE	DOCK7 ARHGEF12 ARHGEF11 ARHGAP21	4.54e-04	94	54	4	MM15598
Pathway	BIOCARTA_PCAF_PATHWAY	RELA CREBBP	5.10e-04	9	54	2	MM1533
Pathway	BIOCARTA_RNA_PATHWAY	RELA EIF2AK2	5.10e-04	9	54	2	MM1382
Pathway	REACTOME_NS1_MEDIATED_EFFECTS_ON_HOST_PATHWAYS	KPNA7 NUP107 EIF2AK2	5.11e-04	41	54	3	M29574
Pathway	REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING	ARHGEF12 RELA ARHGEF2 ARHGEF11	5.12e-04	97	54	4	M9400
Pathway	BIOCARTA_RNA_PATHWAY	RELA EIF2AK2	6.35e-04	10	54	2	M10570
Pathway	REACTOME_SUMOYLATION	NUP107 RELA CHD3 EIF2AK2 CREBBP	7.63e-04	189	54	5	M27214
Pathway	REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE	ARHGEF12 ARHGEF11	7.75e-04	11	54	2	MM15046
Pathway	REACTOME_SUMOYLATION_OF_IMMUNE_RESPONSE_PROTEINS	RELA EIF2AK2	9.27e-04	12	54	2	M27404
Pathway	REACTOME_SARS_COV_2_INFECTION	ANO4 GALNT1 NUP107 HLA-F LARP1 CREBBP	9.51e-04	299	54	6	M41727
Pathway	REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK	ARHGEF12 ARHGEF2 ARHGEF11	1.03e-03	52	54	3	MM14743
Pathway	KEGG_MEDICUS_REFERENCE_LPA_GNA12_13_RHOA_SIGNALING_PATHWAY	ARHGEF12 ARHGEF11	1.09e-03	13	54	2	M47731
Pathway	BIOCARTA_PCAF_PATHWAY	RELA CREBBP	1.09e-03	13	54	2	M22007
Pathway	BIOCARTA_RANKL_PATHWAY	RELA EIF2AK2	1.27e-03	14	54	2	M2602
Pathway	REACTOME_SARS_COV_2_ACTIVATES_MODULATES_INNATE_AND_ADAPTIVE_IMMUNE_RESPONSES	NUP107 HLA-F LARP1 CREBBP	1.36e-03	126	54	4	M45009
Pathway	BIOCARTA_RELA_PATHWAY	RELA CREBBP	1.46e-03	15	54	2	MM1339
Pathway	REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING	ARHGEF12 ARHGEF11	1.46e-03	15	54	2	MM15037
Pathway	BIOCARTA_RELA_PATHWAY	RELA CREBBP	1.46e-03	15	54	2	M10183
Pathway	REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK	ARHGEF12 ARHGEF2 ARHGEF11	1.48e-03	59	54	3	M11215
Pathway	WP_EBOLA_VIRUS_INFECTION_IN_HOST	HLA-F RELA EIF2AK2 CREBBP	1.49e-03	129	54	4	M39693
Pubmed	Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.	DOCK2 ARHGAP6 MFAP1 WBP11 DOCK7 SMARCA4 ARHGEF12 CTNND1 ARHGEF2 SNRNP70 ARHGEF11 AJUBA ARHGAP21	3.82e-08	916	71	13	32203420
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	WBP11 WDR7 DOCK7 SMARCA4 ARHGEF12 NFASC CTNND1 ARHGEF2 PRAF2 ARHGEF11 CCDC177 ARHGAP21 SMG6	6.83e-08	963	71	13	28671696
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	JCAD VPS13D SLC4A7 BORCS5 ANLN DOCK7 LARP1 MIEF1 CTNND1 ARHGEF2 FAM53C ARHGAP21	1.65e-07	861	71	12	36931259
Pubmed	ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.	MFAP1 WBP11 NUP107 ANLN DOCK7 PSMC3 CTNND1 SNRNP70 ARHGEF11 EIF2AK2	9.23e-07	660	71	10	32780723
Pubmed	Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.	MFAP1 SLC4A7 DOCK7 LARP1 MIEF1 CTNND1 ARHGEF2	9.35e-07	255	71	7	15324660
Pubmed	The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.	MFAP1 SLC4A7 ANLN STEEP1 LARP1 CHD3 CTNND1	9.60e-07	256	71	7	33397691
Pubmed	Acetylation of snail modulates the cytokinome of cancer cells to enhance the recruitment of macrophages.	RELA AJUBA CREBBP	9.68e-07	10	71	3	25314079
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	WDR7 DOCK7 SMARCA4 ARHGEF12 PSMC3 LARP1 DGKB NFASC CHD3 CTNND1 ARHGEF2 ARHGEF11 CCDC177 ARHGAP21	1.00e-06	1431	71	14	37142655
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	DOCK2 NUP107 ANLN SMARCA4 PSMC3 CHD3 CTNND1 ARHGEF2 SNRNP70	2.87e-06	582	71	9	20467437
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	MFAP1 WBP11 ANLN ZC3H13 GPATCH1 STEEP1 SMARCA4 LARP1 CHD3 TAF1 SNRNP70	3.56e-06	954	71	11	36373674
Pubmed	Comparative interactome analysis of α-arrestin families in human and Drosophila.	MFAP1 GPATCH1 DOCK7 LARP1 PJA1 CTNND1 ARHGEF2	3.63e-06	313	71	7	38270169
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	SLC4A7 NUP107 WDR7 GPATCH1 DOCK7 MIEF1 RELA PJA1 CTNND1 ARHGAP21	3.95e-06	777	71	10	35844135
Pubmed	A critical role for the transcription factor Scl in platelet production during stress thrombopoiesis.	NFE2 TAL1	4.11e-06	2	71	2	16763211
Pubmed	Role of cyclic AMP response element-binding protein in cyclic AMP inhibition of NF-kappaB-mediated transcription.	RELA CREBBP	4.11e-06	2	71	2	9548485
Pubmed	A small-molecule triptolide suppresses angiogenesis and invasion of human anaplastic thyroid carcinoma cells via down-regulation of the nuclear factor-kappa B pathway.	RELA CREBBP	4.11e-06	2	71	2	19158360
Pubmed	The nuclear factor-kappaB engages CBP/p300 and histone acetyltransferase activity for transcriptional activation of the interleukin-6 gene promoter.	RELA CREBBP	4.11e-06	2	71	2	10542243
Pubmed	Agonist-induced Ca2+ sensitization in smooth muscle: redundancy of Rho guanine nucleotide exchange factors (RhoGEFs) and response kinetics, a caged compound study.	ARHGEF12 ARHGEF11	4.11e-06	2	71	2	24106280
Pubmed	RORα is crucial for attenuated inflammatory response to maintain intestinal homeostasis.	RELA CREBBP	4.11e-06	2	71	2	31570593
Pubmed	Analysis of the RelA:CBP/p300 interaction reveals its involvement in NF-κB-driven transcription.	RELA CREBBP	4.11e-06	2	71	2	24019758
Pubmed	Molecular and biochemical characterization of a novel oxysterol-binding protein (OSBP2) highly expressed in retina.	OSBP OSBP2	4.11e-06	2	71	2	11278871
Pubmed	High levels of cytoplasmic HTLV-1 Tax mutant proteins retain a Tax-NF-kappaB-CBP ternary complex in the cytoplasm.	RELA CREBBP	4.11e-06	2	71	2	15806143
Pubmed	WNT/β-catenin signaling inhibits CBP-mediated RelA acetylation and expression of proinflammatory NF-κB target genes.	RELA CREBBP	4.11e-06	2	71	2	26021349
Pubmed	The Rho GEFs LARG and GEF-H1 regulate the mechanical response to force on integrins.	ARHGEF12 ARHGEF2	4.11e-06	2	71	2	21572419
Pubmed	Human transcription factor protein interaction networks.	MFAP1 WBP11 NUP107 SMARCA4 PSMC3 LARP1 ISX RELA CHD3 TAF1 SNRNP70 TAL1 CREBBP	5.68e-06	1429	71	13	35140242
Pubmed	Dynamic and coordinated expression profile of dbl-family guanine nucleotide exchange factors in the developing mouse brain.	ARHGEF12 ARHGEF2 ARHGEF11	6.51e-06	18	71	3	12799088
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	MFAP1 DOCK7 PNO1 RELA PJA1 CTNND1 SNRNP70 AJUBA FAM53C ARHGAP21 ATG16L2	7.91e-06	1038	71	11	26673895
Pubmed	Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.	MFAP1 WBP11 ANLN STEEP1 DOCK7 SMARCA4 PSMC3 SNRNP70	9.05e-06	506	71	8	30890647
Pubmed	PIAS3 suppresses NF-kappaB-mediated transcription by interacting with the p65/RelA subunit.	RELA CREBBP	1.23e-05	3	71	2	15140884
Pubmed	TGF-β regulates LARG and GEF-H1 during EMT to affect stiffening response to force and cell invasion.	ARHGEF12 ARHGEF2	1.23e-05	3	71	2	25143398
Pubmed	Stimulation of NF-E2 DNA binding by CREB-binding protein (CBP)-mediated acetylation.	NFE2 CREBBP	1.23e-05	3	71	2	11154691
Pubmed	Thrombin and lysophosphatidic acid receptors utilize distinct rhoGEFs in prostate cancer cells.	ARHGEF12 ARHGEF11	1.23e-05	3	71	2	15143072
Pubmed	The LIM protein Ajuba promotes adipogenesis by enhancing PPARγ and p300/CBP interaction.	AJUBA CREBBP	1.23e-05	3	71	2	26113042
Pubmed	Mitophagy antagonism by ZIKV reveals Ajuba as a regulator of PINK1 signaling, PKR-dependent inflammation, and viral invasion of tissues.	AJUBA EIF2AK2	1.23e-05	3	71	2	34706234
Pubmed	Interaction with CREB binding protein modulates the activities of Nrf2 and NF-κB in cystic fibrosis airway epithelial cells.	RELA CREBBP	1.23e-05	3	71	2	22467641
Pubmed	Mechanistic insights into specificity, activity, and regulatory elements of the regulator of G-protein signaling (RGS)-containing Rho-specific guanine nucleotide exchange factors (GEFs) p115, PDZ-RhoGEF (PRG), and leukemia-associated RhoGEF (LARG).	ARHGEF12 ARHGEF11	1.23e-05	3	71	2	21454492
Pubmed	Interaction of plexin-B1 with PDZ domain-containing Rho guanine nucleotide exchange factors.	ARHGEF12 ARHGEF11	1.23e-05	3	71	2	12220504
Pubmed	The transcription factor NFE2 enhances expression of the hematopoietic master regulators SCL/TAL1 and GATA2.	NFE2 TAL1	1.23e-05	3	71	2	32593672
Pubmed	Coactivator function of RIP140 for NFkappaB/RelA-dependent cytokine gene expression.	RELA CREBBP	1.23e-05	3	71	2	18469200
Pubmed	HGAL, a germinal center specific protein, decreases lymphoma cell motility by modulation of the RhoA signaling pathway.	ARHGEF12 ARHGEF11	1.23e-05	3	71	2	20844236
Pubmed	Acetylation of RelA at discrete sites regulates distinct nuclear functions of NF-kappaB.	RELA CREBBP	1.23e-05	3	71	2	12456660
Pubmed	B plexins activate Rho through PDZ-RhoGEF.	ARHGEF12 ARHGEF11	1.23e-05	3	71	2	12372594
Pubmed	Uncoupling of Pyrin-only protein 2 (POP2)-mediated dual regulation of NF-κB and the inflammasome.	RELA NLRP2	1.23e-05	3	71	2	21976665
Pubmed	Regulation of NF-kappaB action by reversible acetylation.	RELA CREBBP	1.23e-05	3	71	2	15171256
Pubmed	CREB-binding protein in androgen receptor-mediated signaling.	RELA CREBBP	1.23e-05	3	71	2	9482849
Pubmed	CREB-binding protein/p300 are transcriptional coactivators of p65.	RELA CREBBP	1.23e-05	3	71	2	9096323
Pubmed	PKR induces the expression of NLRP3 by regulating the NF-κB pathway in Porphyromonas gingivalis-infected osteoblasts.	RELA EIF2AK2	1.23e-05	3	71	2	28341446
Pubmed	Inhibition of NF-kappaB acetylation and its transcriptional activity by Daxx.	RELA CREBBP	1.23e-05	3	71	2	17362989
Pubmed	Secondary PDZ domain-binding site on class B plexins enhances the affinity for PDZ-RhoGEF.	ARHGEF12 ARHGEF11	1.23e-05	3	71	2	26627240
Pubmed	Interferon regulatory factor 3-dependent responses to lipopolysaccharide are selectively blunted in cord blood cells.	RELA CREBBP	1.23e-05	3	71	2	17138826
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	DOCK2 WBP11 ANLN STEEP1 SMARCA4 PSMC3 LARP1 CHD3 ARHGEF2 SNRNP70 CREBBP	1.39e-05	1103	71	11	34189442
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	ANLN STEEP1 DOCK7 SMARCA4 LARP1 TAF1 CTNND1 CREBBP	1.63e-05	549	71	8	38280479
Pubmed	Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.	SMARCA4 TAF1 DNAH9 CREBBP	1.74e-05	75	71	4	25593309
Pubmed	TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions.	WBP11 ZC3H13 DOCK7 PSMC3 LARP1 RELA PJA1 CTNND1 SNRNP70 ARHGAP21	1.75e-05	922	71	10	27609421
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	MFAP1 WBP11 SLC4A7 ANLN SMARCA4 LARP1 MIEF1 CTNND1 ARHGEF2	1.81e-05	733	71	9	34672954
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	JCAD SLC4A7 ANLN ARHGEF12 LARP1 CTNND1 NLRP2 ARHGAP21	2.00e-05	565	71	8	25468996
Pubmed	A bead-based approach for large-scale identification of in vitro kinase substrates.	MFAP1 OSBP ZC3H13 LARP1 SNRNP70	2.16e-05	163	71	5	22113938
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	JCAD NUP107 WDR7 LENG1 SMARCA4 PSMC3 CREBBP ARHGAP21 SORCS1	2.26e-05	754	71	9	35906200
Pubmed	Characterization of monoclonal antibodies raised against p300: both p300 and CBP are present in intracellular TBP complexes.	TAF1 CREBBP	2.46e-05	4	71	2	8995708
Pubmed	Steroid receptor coactivator-1 interacts with the p50 subunit and coactivates nuclear factor kappaB-mediated transactivations.	RELA CREBBP	2.46e-05	4	71	2	9556555
Pubmed	[6]-Gingerol inhibits COX-2 expression by blocking the activation of p38 MAP kinase and NF-kappaB in phorbol ester-stimulated mouse skin.	RELA CREBBP	2.46e-05	4	71	2	15735738
Pubmed	Enhancement of nuclear factor-kappa B acetylation by coactivator p300 and HIV-1 Tat proteins.	RELA CREBBP	2.46e-05	4	71	2	11739381
Pubmed	Herpes simplex virus 1-encoded tegument protein VP16 abrogates the production of beta interferon (IFN) by inhibiting NF-κB activation and blocking IFN regulatory factor 3 to recruit its coactivator CBP.	RELA CREBBP	2.46e-05	4	71	2	23824799
Pubmed	Vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide inhibit CBP-NF-kappaB interaction in activated microglia.	RELA CREBBP	2.46e-05	4	71	2	12372411
Pubmed	Erythroid activator NF-E2, TAL1 and KLF1 play roles in forming the LCR HSs in the human adult β-globin locus.	NFE2 TAL1	2.46e-05	4	71	2	27026582
Pubmed	Centrosomal P4.1-associated protein is a new member of transcriptional coactivators for nuclear factor-kappaB.	RELA CREBBP	2.46e-05	4	71	2	15687488
Pubmed	cAMP-response-element-binding-protein-binding protein (CBP) and p300 are transcriptional co-activators of early growth response factor-1 (Egr-1).	RELA CREBBP	2.46e-05	4	71	2	9806899
Pubmed	NF-kappaB RelA phosphorylation regulates RelA acetylation.	RELA CREBBP	2.46e-05	4	71	2	16135789
Pubmed	Toll-like receptor-mediated cytokine production is differentially regulated by glycogen synthase kinase 3.	RELA CREBBP	2.46e-05	4	71	2	16007092
Pubmed	Histone H3 phosphorylation by IKK-alpha is critical for cytokine-induced gene expression.	RELA CREBBP	2.46e-05	4	71	2	12789342
Pubmed	Repressive LTR nucleosome positioning by the BAF complex is required for HIV latency.	SMARCA4 CHD3	2.46e-05	4	71	2	22140357
Pubmed	Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.	MFAP1 GPATCH1 STEEP1 SMARCA4 CHD3 TAF1	2.53e-05	283	71	6	30585729
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	MFAP1 OSBP ANLN ZC3H13 SMARCA4 LARP1 CHD3 ARHGEF2 FAM53C	2.78e-05	774	71	9	15302935
Pubmed	Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.	GDAP1 LARP1 DGKB NFASC CTNND1 CCDC177 ARHGAP21	2.83e-05	430	71	7	32581705
Pubmed	CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.	MFAP1 WBP11 ZC3H13 SMARCA4 PNO1 LARP1 CHD3 SNRNP70	3.25e-05	605	71	8	28977666
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	NUP107 GPATCH1 SMARCA4 LARP1 CTNND1 ARHGEF2 SNRNP70	3.27e-05	440	71	7	34244565
Pubmed	The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation.	MFAP1 OSBP WBP11 SLC4A7 GALNT1 PCNX3 PSMC3 MIEF1 CTNND1 CDC6	3.69e-05	1007	71	10	34597346
Pubmed	Hypertonicity-responsive ubiquitin ligase RNF183 promotes Na, K-ATPase lysosomal degradation through ubiquitination of its β1 subunit.	SLC4A7 STEEP1 DOCK7 ARHGEF12 PSMC3 LARP1 CTNND1	3.72e-05	449	71	7	31732153
Pubmed	Sipa1 is a candidate for underlying the metastasis efficiency modifier locus Mtes1.	PCNX3 RELA	4.09e-05	5	71	2	16142231
Pubmed	Human immunodeficiency virus type 1 tat protein activates transcription factor NF-kappaB through the cellular interferon-inducible, double-stranded RNA-dependent protein kinase, PKR.	RELA EIF2AK2	4.09e-05	5	71	2	10400814
Pubmed	Galpha 12 activates Rho GTPase through tyrosine-phosphorylated leukemia-associated RhoGEF.	ARHGEF12 ARHGEF11	4.09e-05	5	71	2	12515866
Pubmed	Cell cycle regulation of human interleukin-8 gene expression by the human immunodeficiency virus type 1 Tat protein.	RELA CREBBP	4.09e-05	5	71	2	11160671
Pubmed	BRG-1 is recruited to estrogen-responsive promoters and cooperates with factors involved in histone acetylation.	SMARCA4 CREBBP	4.09e-05	5	71	2	11003650
Pubmed	Recruitment of CBP/p300 by the IFN beta enhanceosome is required for synergistic activation of transcription.	RELA CREBBP	4.09e-05	5	71	2	9659924
Pubmed	Protein kinase Calpha is involved in interferon regulatory factor 3 activation and type I interferon-beta synthesis.	RELA CREBBP	4.09e-05	5	71	2	17296604
Pubmed	Nuclear role of I kappa B Kinase-gamma/NF-kappa B essential modulator (IKK gamma/NEMO) in NF-kappa B-dependent gene expression.	RELA CREBBP	4.09e-05	5	71	2	14597638
Pubmed	BRCA1 augments transcription by the NF-kappaB transcription factor by binding to the Rel domain of the p65/RelA subunit.	RELA CREBBP	4.09e-05	5	71	2	12700228
Pubmed	Phosphorylation of CBP by IKKalpha promotes cell growth by switching the binding preference of CBP from p53 to NF-kappaB.	RELA CREBBP	4.09e-05	5	71	2	17434128
Pubmed	Involvement of TFIID and USA components in transcriptional activation of the human immunodeficiency virus promoter by NF-kappaB and Sp1.	RELA TAF1	4.09e-05	5	71	2	9584164
Pubmed	Plexin B regulates Rho through the guanine nucleotide exchange factors leukemia-associated Rho GEF (LARG) and PDZ-RhoGEF.	ARHGEF12 ARHGEF11	4.09e-05	5	71	2	12183458
Pubmed	Promyelocytic Leukemia Protein Isoform II Promotes Transcription Factor Recruitment To Activate Interferon Beta and Interferon-Responsive Gene Expression.	RELA CREBBP	4.09e-05	5	71	2	25733689
Pubmed	Down regulation of the interleukin-8 promoter by human papillomavirus type 16 E6 and E7 through effects on CREB binding protein/p300 and P/CAF.	RELA CREBBP	4.09e-05	5	71	2	12163591
Pubmed	Molecular basis of nuclear factor-kappaB activation by astrocyte elevated gene-1.	RELA CREBBP	4.09e-05	5	71	2	18316612
Pubmed	A splice variant of stress response gene ATF3 counteracts NF-kappaB-dependent anti-apoptosis through inhibiting recruitment of CREB-binding protein/p300 coactivator.	RELA CREBBP	4.09e-05	5	71	2	16291753
Pubmed	CBP Is a dosage-dependent regulator of nuclear factor-kappaB suppression by the estrogen receptor.	RELA CREBBP	4.09e-05	5	71	2	17932106
Pubmed	The phosphorylation status of nuclear NF-kappa B determines its association with CBP/p300 or HDAC-1.	RELA CREBBP	4.09e-05	5	71	2	11931769
Pubmed	The SWI/SNF chromatin remodeling subunit BRG1 is a critical regulator of p53 necessary for proliferation of malignant cells.	SMARCA4 CREBBP	4.09e-05	5	71	2	19448667
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	MFAP1 ANLN ZC3H13 DOCK7 SMARCA4 PNO1 LARP1 CTNND1 ARHGEF2 AJUBA EIF2AK2	4.61e-05	1257	71	11	36526897
Pubmed	DEPDC1B coordinates de-adhesion events and cell-cycle progression at mitosis.	ARHGEF12 ARHGEF2 ARHGEF11	5.09e-05	35	71	3	25458010
Pubmed	Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	LARP1 DGKB NFASC SMG6	5.61e-05	101	71	4	9872452
Pubmed	Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.	TULP4 NFASC PCDHA6 LTBP2 ARHGEF11 TAL1	5.85e-05	329	71	6	17474147
Interaction	SIRT6 interactions	NUP107 RGL3 GPATCH1 SMARCA4 LARP1 RELA CHD3 CTNND1 ARHGEF2 SNRNP70 NLRP2 CREBBP	1.80e-06	628	71	12	int:SIRT6
Interaction	CIAO2A interactions	IFT140 RGL3 DOCK7 ARHGEF2 PRAF2 NLRP2 EIF2AK2	2.55e-06	173	71	7	int:CIAO2A
Interaction	YWHAH interactions	JCAD VPS13D SLC4A7 BORCS5 ANLN ZC3H13 DOCK7 PSMC3 LARP1 MIEF1 CTNND1 ARHGEF2 CREBBP FAM53C ARHGAP21	5.41e-06	1102	71	15	int:YWHAH
Interaction	YWHAZ interactions	JCAD MFAP1 VPS13D SLC4A7 BORCS5 NUP107 WDR7 ANLN DOCK7 LARP1 MIEF1 CTNND1 ARHGEF2 AJUBA FAM53C ARHGAP21	1.07e-05	1319	71	16	int:YWHAZ
Interaction	SAP18 interactions	ANLN ZC3H13 SMARCA4 RELA CHD3 TAF1 SNRNP70 SMG6	1.17e-05	305	71	8	int:SAP18
Interaction	MEN1 interactions	MFAP1 NUP107 NFE2 ANLN ZC3H13 GPATCH1 SMARCA4 LARP1 RELA CHD3 TAF1 CTNND1 SNRNP70 EIF2AK2	1.18e-05	1029	71	14	int:MEN1
Interaction	DYRK1A interactions	JCAD MFAP1 NUP107 ANLN DOCK7 PJA1 CTNND1 SNRNP70 CREBBP FAM53C	2.26e-05	552	71	10	int:DYRK1A
Interaction	SFN interactions	JCAD OSBP SLC4A7 ANLN DOCK7 LARP1 MIEF1 ARHGEF2 AJUBA FAM53C ARHGAP21	2.84e-05	692	71	11	int:SFN
Interaction	YWHAQ interactions	JCAD VPS13D SLC4A7 BORCS5 NUP107 ANLN ZC3H13 DOCK7 LARP1 MIEF1 CTNND1 ARHGEF2 FAM53C ARHGAP21	2.98e-05	1118	71	14	int:YWHAQ
Interaction	EEF1AKMT3 interactions	IFT140 RGL3 DOCK7 ARHGEF12 RELA ARHGEF2 NLRP2 EIF2AK2	4.14e-05	364	71	8	int:EEF1AKMT3
Interaction	CIITA interactions	NFE2 SMARCA4 PSMC3 CREBBP	4.21e-05	55	71	4	int:CIITA
Interaction	YWHAB interactions	OSBP VPS13D SLC4A7 BORCS5 NUP107 ANLN DOCK7 LARP1 MIEF1 CTNND1 ARHGEF2 FAM53C ARHGAP21	4.70e-05	1014	71	13	int:YWHAB
Interaction	HSF1 interactions	NUP107 LENG1 SMARCA4 PSMC3 LARP1 RELA CHD3 TAF1 CREBBP ATG16L2	5.18e-05	609	71	10	int:HSF1
Interaction	DHX8 interactions	MFAP1 WBP11 ANLN ZC3H13 GPATCH1 STEEP1 SNRNP70	7.51e-05	292	71	7	int:DHX8
Interaction	SUZ12 interactions	MFAP1 NUP107 ZC3H13 GDAP1 SMARCA4 LARP1 RELA CHD3 PJA1 SNRNP70	8.25e-05	644	71	10	int:SUZ12
Interaction	YWHAG interactions	JCAD MFAP1 VPS13D SLC4A7 BORCS5 ANLN ZC3H13 DOCK7 LARP1 MIEF1 CTNND1 ARHGEF2 FAM53C ARHGAP21	9.80e-05	1248	71	14	int:YWHAG
Interaction	BMI1 interactions	WBP11 ZC3H13 DOCK7 SMARCA4 LARP1 CHD3 CTNND1 ARHGEF2 CDC6 CREBBP	9.98e-05	659	71	10	int:BMI1
Interaction	YAP1 interactions	JCAD TULP4 NFE2 STEEP1 SMARCA4 PSMC3 LARP1 RELA TAF1 CTNND1 SNRNP70 AJUBA CREBBP	1.03e-04	1095	71	13	int:YAP1
Interaction	SNIP1 interactions	MFAP1 PCNX3 GPATCH1 SMARCA4 LARP1 RELA SNRNP70 CREBBP	1.07e-04	417	71	8	int:SNIP1
Interaction	FMR1 interactions	ANLN DOCK7 SMARCA4 LARP1 CHD3 ARHGEF2 SNRNP70 ARHGAP21 SMG6	1.07e-04	536	71	9	int:FMR1
Interaction	ARHGEF1 interactions	OSBP WBP11 DOCK7 PSMC3 ARHGEF2	1.18e-04	136	71	5	int:ARHGEF1
Interaction	NUPR1 interactions	MFAP1 WBP11 NUP107 ANLN DOCK7 PSMC3 CTNND1 SNRNP70 ARHGEF11 EIF2AK2	1.34e-04	683	71	10	int:NUPR1
Interaction	ARRDC3 interactions	MFAP1 GPATCH1 DOCK7 LARP1 CTNND1 ARHGEF2	1.38e-04	224	71	6	int:ARRDC3
Interaction	UBXN6 interactions	IFT140 RGL3 DOCK7 ARHGEF12 ARHGEF2 NLRP2 EIF2AK2	1.46e-04	325	71	7	int:UBXN6
Interaction	KRT8 interactions	NUP107 ANLN DOCK7 ARHGEF12 PSMC3 CHD3 SNRNP70 ARHGAP21	1.57e-04	441	71	8	int:KRT8
Interaction	PHLPP1 interactions	MFAP1 SLC4A7 ANLN STEEP1 LARP1 CHD3 CTNND1	1.70e-04	333	71	7	int:PHLPP1
Interaction	SMC5 interactions	MFAP1 WBP11 ANLN ZC3H13 GPATCH1 STEEP1 SMARCA4 LARP1 CHD3 TAF1 PJA1 SNRNP70	1.78e-04	1000	71	12	int:SMC5
Interaction	PLEKHG7 interactions	IFT140 RGL3 CTNND1 SNRNP70 NLRP2	1.87e-04	150	71	5	int:PLEKHG7
Interaction	CDC5L interactions	NUP107 ANLN GPATCH1 STEEP1 SMARCA4 PSMC3 CHD3 CTNND1 ARHGEF2 SNRNP70 EIF2AK2	1.87e-04	855	71	11	int:CDC5L
Interaction	PSENEN interactions	MFAP1 WBP11 ZC3H13 SMG6	1.92e-04	81	71	4	int:PSENEN
Interaction	CIB2 interactions	IFT140 RGL3 DOCK7 NLRP2	1.92e-04	81	71	4	int:CIB2
Interaction	IKBKG interactions	KPNA7 NFE2 ANLN DOCK7 RELA NLRP2 EIF2AK2 CREBBP	2.03e-04	458	71	8	int:IKBKG
Interaction	MARK4 interactions	DOCK7 SMARCA4 PSMC3 ARHGEF2	2.11e-04	83	71	4	int:MARK4
Interaction	GSK3B interactions	VPS13D SIGIRR DOCK7 ARHGEF12 RELA CHD3 CTNND1 SNRNP70 ARHGEF11 NLRP2 ARHGAP21	2.14e-04	868	71	11	int:GSK3B
Interaction	NXF1 interactions	OSBP WBP11 GALNT1 NUP107 ANLN GDAP1 DOCK7 PSMC3 OSBP2 CHD3 TAF1 CTNND1 ARHGEF2 SNRNP70	2.15e-04	1345	71	14	int:NXF1
Interaction	MYBBP1A interactions	NFE2 ANLN SMARCA4 LARP1 RELA CHD3 SNRNP70 TAL1	2.19e-04	463	71	8	int:MYBBP1A
Interaction	ZC3H13 interactions	WBP11 ANLN ZC3H13 CHD3 SNRNP70	2.39e-04	158	71	5	int:ZC3H13
Interaction	PPP1CC interactions	WBP11 ANLN ZC3H13 LARP1 CHD3 SNRNP70 EIF2AK2 CREBBP ARHGAP21 SMG6	2.50e-04	738	71	10	int:PPP1CC
Interaction	MAFK interactions	NFE2 RELA CREBBP	2.99e-04	37	71	3	int:MAFK
Interaction	KCTD13 interactions	WDR7 DOCK7 SMARCA4 ARHGEF12 PSMC3 LARP1 DGKB NFASC CHD3 CTNND1 ARHGEF2 ARHGEF11 CCDC177 ARHGAP21	3.11e-04	1394	71	14	int:KCTD13
Interaction	SRGAP1 interactions	ANLN ARHGEF2 SNRNP70 ARHGAP21	3.13e-04	92	71	4	int:SRGAP1
Interaction	TWIST1 interactions	KPNA7 PSMC3 RELA CHD3 ARHGEF2	3.34e-04	170	71	5	int:TWIST1
Interaction	KHDRBS1 interactions	DOCK2 WBP11 ANLN PSMC3 CHD3 SNRNP70 CREBBP	3.38e-04	373	71	7	int:KHDRBS1
Interaction	LINC02910 interactions	WBP11 ZC3H13 LENG1 SMG6	3.54e-04	95	71	4	int:LINC02910
Interaction	CEBPA interactions	DOCK2 WBP11 NUP107 ANLN STEEP1 SMARCA4 PSMC3 LARP1 CHD3 ARHGEF2 SNRNP70 CREBBP NAA16	3.63e-04	1245	71	13	int:CEBPA
Interaction	GLI3 interactions	NUP107 SMARCA4 TAF1 CREBBP	3.98e-04	98	71	4	int:GLI3
Interaction	GNL2 interactions	MFAP1 WBP11 ANLN ZC3H13 CHD3 SNRNP70 EIF2AK2	4.15e-04	386	71	7	int:GNL2
Interaction	NKX2-1 interactions	NUP107 SMARCA4 PSMC3 RELA CREBBP	4.35e-04	180	71	5	int:NKX2-1
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	OSBP ANLN OSBP2 ARHGEF2 ARHGAP21	2.10e-04	206	48	5	682
GeneFamily	Oxysterol binding proteins\|Pleckstrin homology domain containing	OSBP OSBP2	4.48e-04	12	48	2	670
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	ARHGEF12 ARHGEF2 ARHGEF11	7.15e-04	66	48	3	722
GeneFamily	Zinc fingers ZZ-type\|Lysine acetyltransferases	TAF1 CREBBP	9.15e-04	17	48	2	486
GeneFamily	Sulfotransferases, membrane bound	HS6ST1 GAL3ST3	4.33e-03	37	48	2	763
GeneFamily	WD repeat domain containing	IFT140 TULP4 WDR7 ATG16L2	5.09e-03	262	48	4	362
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	KPNA7 CTNND1	5.81e-03	43	48	2	409
GeneFamily	PDZ domain containing	ARHGEF12 ARHGEF11 ARHGAP21	7.64e-03	152	48	3	1220
GeneFamily	Rho GTPase activating proteins\|BCH domain containing	ARHGAP6 ARHGAP21	7.80e-03	50	48	2	721
Coexpression	GSE40655_FOXO1_KO_VS_WT_NTREG_UP	MFAP1 PCNX3 TULP4 ARHGEF12 RELA CHD3 SNRNP70	1.19e-06	200	71	7	M9439
Coexpression	GSE16385_IFNG_TNF_VS_UNSTIM_MACROPHAGE_ROSIGLITAZONE_TREATED_UP	MFAP1 RELA VAT1L CDC6 ARHGEF11 EIF2AK2	1.30e-05	190	71	6	M8021
Coexpression	SCHEIDEREIT_IKK_INTERACTING_PROTEINS	RELA NLRP2 EIF2AK2 CREBBP	1.31e-05	53	71	4	M6303
Coexpression	GSE1432_CTRL_VS_IFNG_24H_MICROGLIA_UP	SLC4A7 GALNT1 TULP4 CHD3 LTBP2 TAL1	1.74e-05	200	71	6	M3407
Coexpression	VALK_AML_CLUSTER_8	ARHGEF12 OSBP2 TAL1	4.20e-05	25	71	3	M6241
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1\|TCGA-Pancreas / Sample_Type by Project: Shred V9	ARHGAP6 VPS13D ZC3H13 ARHGEF12 TAF1 CREBBP	5.28e-07	186	71	6	03db813598b67b1e08f759758a1c2023396921fa
ToppCell	wk_20-22-Hematologic-Meg-ery-Cycling_definitive_erythroblast\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	NFE2 ANLN OSBP2 AMMECR1 TAL1	9.14e-06	176	71	5	98814f0a67411b2f7b25dc489b2aadb77f45a853
ToppCell	10x5'v1-week_17-19-Myeloid_macrophage-stroma-erythroid_macrophage\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	RGL3 ARHGEF12 OSBP2 LY6K TAL1	9.40e-06	177	71	5	b647667da62a91dbe3890820142626e26aa779d2
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-Mast-Mast-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NFE2 OSBP2 AMMECR1 TAL1 NLRP2	1.05e-05	181	71	5	c35ca98c474e31917e0a53c092397e0d8d18b37c
ToppCell	LV-07._Pericyte\|World / Chamber and Cluster_Paper	ARHGAP6 VPS13D RGL3 DGKB NFASC	1.10e-05	183	71	5	273db6a3b00a93ca852498471187b642b5368185
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGAP6 SLC4A7 RGL3 LTBP2 NAALADL2	1.39e-05	192	71	5	562df5e87038c500dd3a003fe5374cb31946b145
ToppCell	Megakaryocytic-erythropoietic\|World / Lineage, cell class and subclass	ARHGAP6 NFE2 ARHGEF12 OSBP2 TAL1	1.43e-05	193	71	5	805c2e2e5d8a9df5ce796d5c0206d6493ab53c88
ToppCell	wk_08-11-Hematologic-Meg-ery-Definitive_erythroblast\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	NFE2 ARHGEF12 LARP1 OSBP2 TAL1	1.43e-05	193	71	5	be75abfdf5301cf33df8ee9ed92504d44fdf19a6
ToppCell	21-Trachea-RBC\|Trachea / Age, Tissue, Lineage and Cell class	NFE2 OSBP2 AMMECR1 CDC6 TAL1	1.58e-05	197	71	5	9f8eb6305ade0654bbcd8f19963be0b64af083de
ToppCell	erythropoietic-Polychromatic_Erythroblast\|World / Lineage and Cell class	NFE2 OSBP2 AMMECR1 CDC6 TAL1	1.58e-05	197	71	5	604fcbf47f073c2af344e1b16b615a78ef838dc9
ToppCell	21-Trachea-RBC-RBC\|Trachea / Age, Tissue, Lineage and Cell class	NFE2 OSBP2 AMMECR1 CDC6 TAL1	1.58e-05	197	71	5	4710b55806a618076a954190f519e49c55d300d3
ToppCell	facs-Spleen-nan-18m-Hematologic-proerythroblast\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NFE2 DOCK7 CDC6 TAL1	1.43e-04	166	71	4	8d535fab019356894b4dad3fbdbc4d2ad3e16082
ToppCell	facs-Spleen-nan-18m-Hematologic-nan\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NFE2 DOCK7 CDC6 TAL1	1.43e-04	166	71	4	f56b1c0d6cb5353a16a2598bda905287f16d2c39
ToppCell	facs-Spleen-nan-18m-Hematologic\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NFE2 DOCK7 CDC6 TAL1	1.43e-04	166	71	4	a5074c96c6561273029aceb93402a7e038140f50
ToppCell	Bronchial_Biopsy-Immune-Mast_cells\|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X	JCAD GDAP1 TAL1 NAALADL2	1.50e-04	168	71	4	45ccc0cb42d21f4853190e8e9ed9a54aefefe738
ToppCell	TCGA-Endometrium-Solid_Tissue_Normal-Endometrium_normal_tissue-Endometrium-7\|TCGA-Endometrium / Sample_Type by Project: Shred V9	JCAD ARHGAP6 DGKB TAL1	1.50e-04	168	71	4	a97e8e07ba949b30805aeed5f60fa5e092b9d3d4
ToppCell	wk_20-22-Hematologic-Meg-ery-Megakaryocyte\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	ARHGAP6 NFE2 OSBP2 TAL1	1.57e-04	170	71	4	eace4dd09cdbde0fa40a6aa0f3dba1114d0ce475
ToppCell	TCGA-Endometrium-Solid_Tissue_Normal-Endometrium_normal_tissue-Endometrium\|TCGA-Endometrium / Sample_Type by Project: Shred V9	JCAD ARHGAP6 DGKB TAL1	1.57e-04	170	71	4	cdc19013da7c41d1ed8400a6a643e4c684ff9912
ToppCell	TCGA-Endometrium-Solid_Tissue_Normal\|TCGA-Endometrium / Sample_Type by Project: Shred V9	JCAD ARHGAP6 DGKB TAL1	1.57e-04	170	71	4	0bde0a40440c7fdf7ba89cac8831d4014e7a4807
ToppCell	TCGA-Endometrium-Solid_Tissue_Normal-Endometrium_normal_tissue\|TCGA-Endometrium / Sample_Type by Project: Shred V9	JCAD ARHGAP6 DGKB TAL1	1.57e-04	170	71	4	516b38c4ecf6b0b04c5d4f80c510dcc00b328c6f
ToppCell	343B-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	NFE2 PRKG2 CDC6 TAL1	1.60e-04	171	71	4	4ccd88cf812dd8bfdc55159c6f504e9c84e4f4fc
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	JCAD GALNT1 AJUBA TAL1	1.64e-04	172	71	4	c056d44e2e130ceccadfcdceb192a7f095d779c8
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGAP6 SLC4A7 VAT1L NAALADL2	1.75e-04	175	71	4	e5467dacf81f1f913b1719931cf1a7331434a7e7
ToppCell	18-Distal-RBC-RBC\|Distal / Age, Tissue, Lineage and Cell class	DOCK2 NFE2 LARP1 TAL1	1.75e-04	175	71	4	7130b816e0c02309c161d8e9ad7cb4bc2469e251
ToppCell	18-Distal-RBC\|Distal / Age, Tissue, Lineage and Cell class	DOCK2 NFE2 LARP1 TAL1	1.75e-04	175	71	4	cc476b4244442418b8f21721a82a36209b556b36
ToppCell	droplet-Marrow-BM-30m-Hematologic-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IFT140 HS6ST1 CDC6 TAL1	1.83e-04	177	71	4	650095a17e1a39caea74a6e89646565b9332af5d
ToppCell	droplet-Marrow-BM-30m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IFT140 HS6ST1 CDC6 TAL1	1.83e-04	177	71	4	d1af0cb4b1fb03f04cff5add85e29be8fb8f4dcb
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-hematologic-erythrocytic-erythrocyte\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	NFE2 ARHGEF12 OSBP2 TAL1	1.91e-04	179	71	4	dfefa4b7ae0ee50cf67e0f1938c682f08a03ec53
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-hematologic-erythrocytic\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	NFE2 ARHGEF12 OSBP2 TAL1	1.91e-04	179	71	4	64672528f73ac0921f9c7df72e14ecbfac4d5270
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-hematologic\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	NFE2 ARHGEF12 OSBP2 TAL1	1.91e-04	179	71	4	fa0dd87111d399649cdea55f2e610ebc169e8a56
ToppCell	18-Airway-RBC\|Airway / Age, Tissue, Lineage and Cell class	NFE2 OSBP2 AMMECR1 TAL1	1.95e-04	180	71	4	35bf5f35cf346a5b27f5e819b77db34130d70db1
ToppCell	18-Airway-RBC-RBC\|Airway / Age, Tissue, Lineage and Cell class	NFE2 OSBP2 AMMECR1 TAL1	1.95e-04	180	71	4	3b4b220a3c150426ae55239baff756f1a7f1e1d7
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Hematopoietic\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	NFE2 OSBP2 PRKG2 TAL1	1.99e-04	181	71	4	9dc0563453e24c9d1d975e2e0e1e272487e19908
ToppCell	3'-GW_trimst-2-SmallIntestine-Hematopoietic-Red_blood_cells\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VPS13D NFE2 OSBP2 TAL1	1.99e-04	181	71	4	fe2f8b4bd8b09be8ba933529a16e1dca08740dab
ToppCell	HSPCs-Erythroblasts\|HSPCs / Lineage and Cell class	IFT140 AMMECR1 CDC6 TAL1	1.99e-04	181	71	4	4ded490f190af7ace343acdf317edc7373484d08
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Hematopoietic-Megakaryocytic\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	NFE2 OSBP2 PRKG2 TAL1	1.99e-04	181	71	4	14c2dd946e89ba578711c2d25935b6b3d319b701
ToppCell	HSPCs-Erythroblasts\|World / Lineage and Cell class	IFT140 AMMECR1 CDC6 TAL1	1.99e-04	181	71	4	ce26f1accc8f69b7bc4b929073e975c887566c6a
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Hematopoietic-Megakaryocytic-Megakaryocyte\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	NFE2 OSBP2 PRKG2 TAL1	1.99e-04	181	71	4	c5843b89f3d362e236ff76c3279518a2fdfc1f75
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Hematopoietic-Megakaryocytic-Megakaryocyte-Mega\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	NFE2 OSBP2 PRKG2 TAL1	1.99e-04	181	71	4	fcefb5902416c004631f4f8dd5c8f99fe3bd90bc
ToppCell	356C-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|356C / Donor, Lineage, Cell class and subclass (all cells)	NFE2 PRKG2 CDC6 TAL1	1.99e-04	181	71	4	be4f35c9eb5b3083acb2264128f095fac1f3da45
ToppCell	3'-GW_trimst-2-SmallIntestine-Hematopoietic-Red_blood_cells-RBC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VPS13D NFE2 OSBP2 TAL1	1.99e-04	181	71	4	a16079b1c832456b974d9d06dd1a3eda63ac1bce
ToppCell	wk_20-22-Hematologic-Meg-ery-Definitive_erythroblast\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	NFE2 ARHGEF12 OSBP2 TAL1	2.04e-04	182	71	4	0c77ef4556c1d1512ebe9077df858b28f9e38dd5
ToppCell	Fetal_29-31_weeks-Immune-enucleated_erythrocyte-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NFE2 ANLN OSBP2 TAL1	2.04e-04	182	71	4	a99d48084aa6f5c34f4a622ae6c2165db7f0beff
ToppCell	LA-07._Pericyte\|World / Chamber and Cluster_Paper	ARHGAP6 RGL3 DGKB NFASC	2.08e-04	183	71	4	e3835db4795362b0442d5893baf2a78efcc20428
ToppCell	wk_15-18-Hematologic-Myeloid-MEP\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	NFE2 CDC6 TAL1 NLRP2	2.12e-04	184	71	4	19d61d0ab038b7e729e13a46f88b8cf31759485d
ToppCell	3'_v3-lymph-node_spleen-Hematopoietic_Erythro-Mega-Megakaryocyte_early\|lymph-node_spleen / Manually curated celltypes from each tissue	ARHGAP6 ARHGEF12 OSBP2 TAL1	2.12e-04	184	71	4	10607d7d92edcbb92d992900086b90b307421cc3
ToppCell	wk_15-18-Hematologic-Meg-ery-Cycling_definitive_erythroblast\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	NFE2 OSBP2 AMMECR1 TAL1	2.12e-04	184	71	4	238eba615b4e04967d44ac7858a6673bdd7f67e9
ToppCell	COVID-19-Heart-Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	ARHGAP6 RGL3 DGKB NFASC	2.12e-04	184	71	4	21790cdfa3b4036ad413fd44b94e31563116f25f
ToppCell	MS-IIF-Others-RBC\|IIF / Disease, condition lineage and cell class	NFE2 OSBP2 LTBP2 TAL1	2.12e-04	184	71	4	578bde79b464ed12dd9a53dd8e2839e156220a60
ToppCell	PBMC-Severe-Hematopoietic-RBC\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	NFE2 ARHGEF12 OSBP2 TAL1	2.17e-04	185	71	4	d685a5a2e525db2eba449cfa1e5cd54eb36162a8
ToppCell	PBMC-Severe-Hematopoietic-RBC\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	NFE2 ARHGEF12 OSBP2 TAL1	2.17e-04	185	71	4	5d8d6fd7800f76ee3aa5cef95241d8e6d7e8db04
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Hematopoietic\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	ARHGAP6 NFE2 OSBP2 TAL1	2.17e-04	185	71	4	c985a4b184d382a79aaff07f81c0efede2c2d493
ToppCell	PBMC-Severe-Hematopoietic-RBC-RBC\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	NFE2 ARHGEF12 OSBP2 TAL1	2.17e-04	185	71	4	100b5afdf3c6ab07ffc493f7883f5a7b31c59184
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Hematopoietic-Megakaryocytic-Megakaryocyte\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	ARHGAP6 NFE2 OSBP2 TAL1	2.17e-04	185	71	4	d0d0e000ebe1fc35a987930ceaf7e3369e0c694c
ToppCell	COVID-19_Severe-Hematopoietic_R\|COVID-19_Severe / Disease group, lineage and cell class	NFE2 ARHGEF12 OSBP2 TAL1	2.17e-04	185	71	4	30f064ab7c3890e6f419a845276b145112e78f52
ToppCell	droplet-Marrow-nan-18m-Hematologic-erythroblast\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IFT140 HS6ST1 CDC6 TAL1	2.17e-04	185	71	4	a45756f91b62cf0fac3582786e5868deb8fd8435
ToppCell	PBMC-Severe-Hematopoietic-RBC-RBC\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	NFE2 ARHGEF12 OSBP2 TAL1	2.17e-04	185	71	4	f3b1907c3b6f930bc161f46efce5e143babab507
ToppCell	PBMC-Severe-Hematopoietic-RBC-RBC-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	NFE2 ARHGEF12 OSBP2 TAL1	2.17e-04	185	71	4	44ce50cb99df8ffc50eba311adcf688477618659
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGAP6 SLC4A7 VAT1L NAALADL2	2.17e-04	185	71	4	03f64a7132b13a01ba47187e0e15c13ac88f7cb2
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Hematopoietic-Megakaryocytic\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	ARHGAP6 NFE2 OSBP2 TAL1	2.17e-04	185	71	4	0ca99fcbd30c454bcdc2aa5265a0e4dba25666ea
ToppCell	PBMC-Severe-Hematopoietic-RBC-RBC-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	NFE2 ARHGEF12 OSBP2 TAL1	2.17e-04	185	71	4	17542ccd52a821c9e99b1a7469e80502e764b3fd
ToppCell	LA-07._Pericyte\|LA / Chamber and Cluster_Paper	ARHGAP6 RGL3 DGKB NFASC	2.17e-04	185	71	4	ba5baa4d7f097108622674de5b7f4fd279843d24
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Hematopoietic-Megakaryocytic-Megakaryocyte-Mega\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	ARHGAP6 NFE2 OSBP2 TAL1	2.17e-04	185	71	4	0f722ffcc3e78d5c6b1b79d31d00929801a993f1
ToppCell	COVID-19_Severe-RBC\|World / disease group, cell group and cell class	NFE2 ARHGEF12 OSBP2 TAL1	2.17e-04	185	71	4	96b7058b1b282134970aa9e75285760a9f94a8b5
ToppCell	COVID-19_Severe-Hematopoietic_R-RBC\|COVID-19_Severe / Disease group, lineage and cell class	NFE2 ARHGEF12 OSBP2 TAL1	2.17e-04	185	71	4	3ed6090b822c6d1d400a421236cddc7511743932
ToppCell	LV-07._Pericyte\|LV / Chamber and Cluster_Paper	ARHGAP6 RGL3 DGKB NFASC	2.17e-04	185	71	4	acb38eba871ec72f2a8136a33b87d33b8c85465d
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGAP6 SLC4A7 VAT1L NAALADL2	2.21e-04	186	71	4	1850583d23903d08226aeb0edb3e07b0994330e4
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGAP6 SLC4A7 VAT1L NAALADL2	2.21e-04	186	71	4	4dafc215c42e7949f932a3627359c107943b5d6b
ToppCell	severe-Others\|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	ARHGAP6 ARHGEF12 OSBP2 TAL1	2.21e-04	186	71	4	234a4bc7c3529daf8804f2a366887d02a47075cd
ToppCell	RV-07._Pericyte\|RV / Chamber and Cluster_Paper	ARHGAP6 RGL3 DGKB NFASC	2.21e-04	186	71	4	c533b264fbe12bc35467486fc7fbde24ba968fe1
ToppCell	IIF-Other\|IIF / Disease, Lineage and Cell Type	ARHGAP6 NFE2 OSBP2 TAL1	2.26e-04	187	71	4	ae44d9261698cc0289750a546baf050f78b119b3
ToppCell	severe-Others-Megakaryocytes\|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	ARHGAP6 ARHGEF12 OSBP2 TAL1	2.26e-04	187	71	4	ef16331d1e5abe6bde7f09793c4a87a6ac24e592
ToppCell	Multiple_Sclerosis-Other\|Multiple_Sclerosis / Disease, Lineage and Cell Type	ARHGAP6 NFE2 OSBP2 TAL1	2.26e-04	187	71	4	ca6f53e841fd016804e6e8ccf0199877b0e5cbdd
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Hematopoietic\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ARHGAP6 NFE2 OSBP2 TAL1	2.26e-04	187	71	4	46e15419e80bd7180f3171a99d845b01bb635e53
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Hematopoietic-Megakaryocytic-Megakaryocyte\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ARHGAP6 NFE2 OSBP2 TAL1	2.26e-04	187	71	4	0d17b07770e4c881a7ca53a5bd42471457d198fb
ToppCell	RV-07._Pericyte\|World / Chamber and Cluster_Paper	ARHGAP6 RGL3 DGKB NFASC	2.26e-04	187	71	4	dc274d6bbda619a2c914d84e2b4069cfef1739d1
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Hematopoietic-Megakaryocytic\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ARHGAP6 NFE2 OSBP2 TAL1	2.26e-04	187	71	4	69068480f6819a6c8560ecbb05deb156b4055e12
ToppCell	wk_08-11-Hematologic-Meg-ery-Cycling_definitive_erythroblast\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	NFE2 OSBP2 AMMECR1 TAL1	2.26e-04	187	71	4	c0965293f08d3e49000871777a5b26d81a4af203
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Hematopoietic-Megakaryocytic-Megakaryocyte-Mega\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ARHGAP6 NFE2 OSBP2 TAL1	2.26e-04	187	71	4	9c8b932a15b8b50982cba4cf8db750e257eb9503
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGAP6 RGL3 LTBP2 NAALADL2	2.31e-04	188	71	4	2ee64bc73a2251fd9f374be759b442cf4ed0d19e
ToppCell	Influenza_Severe-RBC\|World / Disease group and Cell class	ANLN ARHGEF12 OSBP2 TAL1	2.31e-04	188	71	4	f0438e6a77ee1f0456cb65926685266fff470983
ToppCell	droplet-Marrow-BM-30m-Hematologic-erythroblast\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IFT140 HS6ST1 CDC6 TAL1	2.31e-04	188	71	4	f1a9d8ea174a4bef0fae8188e3bd96b7ac1a39bb
ToppCell	control-immature_Neutrophil\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	NFE2 CTNND1 ARHGEF11 FAM53C	2.35e-04	189	71	4	bdfd120900ba58d5e54765f7b576e1f8cc2401bf
ToppCell	Megakaryocytic-erythropoietic-Erythro-cells-Erythrocyte\|World / Lineage, cell class and subclass	NFE2 ARHGEF12 OSBP2 TAL1	2.35e-04	189	71	4	826457adac7477102f86aceb97a8b77929b3e6f9
ToppCell	Healthy/Control-Platelet\|Healthy/Control / Disease group and Cell class	ARHGAP6 NFE2 OSBP2 TAL1	2.35e-04	189	71	4	3de7f8d8b8451ed9a146cce499552e9a060e9099
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ANO4 JCAD LTBP2 VAT1L	2.35e-04	189	71	4	0abc7a4900cc9033bc1be69b770ccc54a6bf41b4
ToppCell	Megakaryocytic-erythropoietic-Erythro-cells\|World / Lineage, cell class and subclass	NFE2 ARHGEF12 OSBP2 TAL1	2.40e-04	190	71	4	6c7e016a9b425ee9418acd4fe96b9779fe7bd39a
ToppCell	PND10\|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	JCAD SMARCA4 ARHGEF12 LTBP2	2.40e-04	190	71	4	d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGAP6 SLC4A7 RGL3 LTBP2	2.40e-04	190	71	4	3dcadabbefe0128a5f30ab51234f049ab4d870c6
ToppCell	severe_COVID-19-RBC\|severe_COVID-19 / disease group, cell group and cell class (v2)	NFE2 ARHGEF12 OSBP2 TAL1	2.40e-04	190	71	4	3a5723c2daf58c1932edd70910db4b8b30f63f42
ToppCell	severe_COVID-19-RBC\|World / disease group, cell group and cell class (v2)	NFE2 ARHGEF12 OSBP2 TAL1	2.50e-04	192	71	4	1b4e28fd2e3d70ab48dbe96b280d35395889fbe2
ToppCell	PBMC-Severe-Hematopoietic\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ARHGAP6 ARHGEF12 OSBP2 TAL1	2.50e-04	192	71	4	68d0bf6249a24d23cb1b0be434bced2ff2d0f2b4
ToppCell	PBMC-Severe-Hematopoietic\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	ARHGAP6 ARHGEF12 OSBP2 TAL1	2.50e-04	192	71	4	3b75fe82018bb259b02bfaee96b310f4d6df0350
ToppCell	MS-Treg-exh_CD4\|MS / Condition, Cell_class and T cell subcluster	BORCS5 DOCK7 ARHGEF12 AMMECR1	2.50e-04	192	71	4	c6722bf142c84ccedd99c1a3344085aecb4cbab4
ToppCell	wk_20-22-Mesenchymal-Myofibro_&_SMC-Vascular_SMC_2\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	DGKB NFASC LTBP2 PRKG2	2.50e-04	192	71	4	a7d08416f07f29ad920168a3b52ddf992f263bf4
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	ANO4 JCAD LTBP2 CDC6	2.55e-04	193	71	4	bbdfda6665941cfa1965418bb91ef9ff43b1326f
ToppCell	severe_influenza-RBC\|severe_influenza / disease group, cell group and cell class (v2)	ANLN ARHGEF12 OSBP2 TAL1	2.55e-04	193	71	4	ffb0b3c2cce13b6891157f0fede2600f3938670e
ToppCell	10x3'2.3-week_17-19-Hematopoietic-erythroid-late_erythroid\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	NFE2 ARHGEF12 OSBP2 TAL1	2.60e-04	194	71	4	23b06707d21306b4483d64cb350b86aef352ce38
ToppCell	356C-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	NFE2 PRKG2 CDC6 TAL1	2.65e-04	195	71	4	751cb00b0f3005be6b645adadfbb9dd2215b6e08
ToppCell	15-Distal-Mesenchymal-Airway_Smooth_Muscle\|Distal / Age, Tissue, Lineage and Cell class	ANO4 ARHGAP6 LTBP2 VAT1L	2.70e-04	196	71	4	0e45817625b96d21a8cc4dfbbd465ee6403b6802
Disease	severe acute respiratory syndrome, COVID-19	ARHGAP6 BORCS5 GDAP1 DGKB NFASC PCDHA6 LTBP2 EIF2AK2	1.20e-05	447	71	8	EFO_0000694, MONDO_0100096
Disease	Sezary Syndrome	SMARCA4 CHD3 CREBBP	3.75e-05	27	71	3	C0036920
Disease	factor XI measurement, coronary artery disease	JCAD ANLN SMARCA4 SMG6	1.74e-04	115	71	4	EFO_0001645, EFO_0004694
Disease	mean arterial pressure	SLC4A7 PCNX3 WDR7 RGL3 ARHGEF12 SNRNP70 SMG6	1.98e-04	499	71	7	EFO_0006340
Disease	angina pectoris	PCNX3 SMARCA4 ARHGEF12 SMG6	2.39e-04	125	71	4	EFO_0003913
Disease	pneumococcal bacteremia	DOCK2 DOCK7	3.10e-04	11	71	2	EFO_1001925
Disease	Mitral valve prolapse, response to surgery	LTBP2 SMG6	3.71e-04	12	71	2	EFO_0009951, HP_0001634
Disease	PROSTATE CANCER, HEREDITARY, 1	DOCK2 ARHGAP6 CHD3	4.14e-04	60	71	3	C4722327
Disease	pulse pressure measurement	JCAD SLC4A7 WDR7 RGL3 ARHGEF12 PNO1 PCDHA6 LTBP2 CTNND1 SNRNP70 SMG6	4.69e-04	1392	71	11	EFO_0005763
Disease	Prostate cancer, familial	DOCK2 ARHGAP6 CHD3	6.24e-04	69	71	3	C2931456
Disease	behavioural disinhibition measurement	KPNA7 RELA DNAH9	7.96e-04	75	71	3	EFO_0006946
Disease	hypertension	SLC4A7 RGL3 ARHGEF12 PSMC3 PNO1	8.77e-04	307	71	5	EFO_0000537
Disease	sensorineural hearing loss (implicated_via_orthology)	PSMC3 DNAH9	9.51e-04	19	71	2	DOID:10003 (implicated_via_orthology)
Disease	Ischemic stroke	GALNT1 SMARCA4 CHD3 VAT1L ARHGAP21	1.11e-03	324	71	5	HP_0002140
Disease	sleep duration, low density lipoprotein cholesterol measurement	DOCK7 SMARCA4 VAT1L	1.39e-03	91	71	3	EFO_0004611, EFO_0005271
Disease	unipolar depression, neuroticism measurement	ANO4 ARHGAP21	1.52e-03	24	71	2	EFO_0003761, EFO_0007660
Disease	gamma-glutamyltyrosine measurement	ARHGEF2 ARHGAP21	1.93e-03	27	71	2	EFO_0021144
Disease	coronary artery disease	JCAD IFT140 PCNX3 RGL3 SMARCA4 ARHGEF12 ARHGAP21 ATG16L2 SMG6	2.21e-03	1194	71	9	EFO_0001645
Disease	NEPHROTIC SYNDROME, STEROID-RESISTANT, AUTOSOMAL RECESSIVE	NUP107 ANLN	2.38e-03	30	71	2	C1868672

Protein segments in the cluster

Peptide	Gene	Start	Entry
FMPASKEEPIRLLRE	SMG6	1371	Q86US8
MRERRETLALAPEPE	ATG16L2	246	Q8NAA4
FVPEAARARMREPEA	AJUBA	316	Q96IF1
TLMEARFPEGPERRE	ARHGEF2	761	Q92974
KENLMPREELARLFP	ARHGEF11	766	O15085
PDPAALKDRRMENLV	CREBBP	616	Q92793
IPDLPKDLRDRMRRE	ANO4	906	Q32M45
PDEMSADLEKRRPEL	ARHGEF12	441	Q9NZN5
ILKRPARRSDMDRPE	ISX	36	Q2M1V0
RFDSDAAIPRMEPRE	HLA-F	56	P30511
DAPIRQKMPLDDLDR	NUP107	326	P57740
PRLFRMASKDREDLL	PCDHA6	61	Q9UN73
GKFRRLEDFRVDPPM	LARP1	1016	Q6PKG0
MPTLDAPEERRRKFK	KPNA7	1	A9QM74
SEDEMEPRLKPVFIR	MFAP1	191	P55081
AMERPKPEEKRFLLE	LY6K	91	Q17RY6
PDEKIKSRLDPLREM	LENG1	146	Q96BZ8
MDPFTEKLLERTRAR	ANLN	1	Q9NQW6
PRRADPDRLMRMKEV	JCAD	1251	Q9P266
KMQIDEREEFGPRLP	GPATCH1	821	Q9BRR8
PRMEDSGPLRDIKEL	PCNX3	151	Q9H6A9
VPGERFRELMDKFLR	NAA16	301	Q6N069
FLDERTPRLMPDKES	GDAP1	101	Q8TB36
PRDPIKAKLREDEAM	LRRC71	541	Q8N4P6
TRKERPPLDVDEMLE	NLRP2	111	Q9NX02
AELRSFLRAKLPDMP	MIEF1	166	Q9NQG6
RMDTEEARPAKRPVF	PNO1	46	Q9NRX1
SPVAPRDFMLRRKEG	RGL3	686	Q3MIN7
APTDSRLRPDQRLME	OSBP	711	P22059
APTDSRLRPDQRLME	OSBP2	816	Q969R2
PVRELERSLRFDMKG	HS6ST1	71	O60243
IEKMDFPRKITRRPE	PRKG2	666	Q13237
EFLRDMPDPLLTREL	ARHGAP6	471	O43182
LEVKDPTRIYRMPED	NFASC	516	O94856
RFDRAELERLMPPST	GAL3ST3	131	Q96A11
PQREMDRRKGDRTLP	GALNT1	271	Q10472
EMPDFDDRRVGRPRS	DOCK2	1621	Q92608
APRKSRFPERFMDDI	DOCK7	1031	Q96N67
RSLAPRFDLPDMKET	EIF2AK2	241	P19525
RMPDKDDIRLLPSAL	CHD3	31	Q12873
ERLEPFSMKPDRELR	BORCS5	181	Q969J3
ERGRPEDKLEFMFRL	DGKB	146	Q9Y6T7
TAVPDRLPAREREMD	CDC6	166	Q99741
MRKAEEEELARPPRE	LTBP2	741	Q14767
MREEKRRLFTPLSPA	CCDC177	156	Q9NQR7
DPDRPEDQVLMRSLR	DNAH9	2061	Q9NYC9
EDPRRLRPSLDFDKM	FAM53C	291	Q9NYF3
RFEVPRMLSEDLPSL	IFT140	931	Q96RY7
PSDPRRRLRSYEDMI	CTNND1	311	O60716
DERRALAMKIPFPTD	NFE2	226	Q16621
PPTRAETREERMERK	SNRNP70	56	P08621
EKLPMRPRDRSRVID	STEEP1	46	Q9H5V9
MERFRLEKKLPGPDE	SLC4A7	1	Q9Y6M7
RVKRRPSPYEMEITD	TAL1	166	P17542
RPRRIRMEDIKKAFP	TAF1	821	P21675
EEARNPKRKPRLMEE	SMARCA4	1326	P51532
DDKDPMLILRGRVPE	SIGIRR	326	Q6IA17
ALKDSRFPPMTRDEL	AMMECR1	196	Q9Y4X0
RISKLRPEFVIMDPR	TULP4	476	Q9NRJ4
MSEVRLPPLRALDDF	PRAF2	1	O60831
GRLDRKIEFPMPNEE	PSMC3	346	P17980
LRLFRKAMPEPQDGE	VAT1L	56	Q9HCJ6
FALDLPPRRRDEDML	WBP11	221	Q9Y2W2
DPDKATRFRMEELRL	SORCS1	146	Q8WY21
ADRLKLRPRAPADDM	ARHGAP21	1766	Q5T5U3
QLRRPSDRELSEPME	RELA	271	Q04206
EKVPRRRRTMADPDF	PJA1	336	Q8NG27
LDKFRPPLLEMLARR	WDR7	1001	Q9Y4E6
RSPERPTGDLRERMK	ZC3H13	76	Q5T200
TDNRYEPLMLRKPDR	VPS13D	3691	Q5THJ4
DPKERAPIRIRMLND	NAALADL2	696	Q58DX5