Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	histone H4K20 methyltransferase activity	KMT5B NSD1	2.62e-04	10	49	2	GO:0042799
GeneOntologyMolecularFunction	protein-lysine N-methyltransferase activity	KMT5B NSD1 KMT2A	6.22e-04	68	49	3	GO:0016279
GeneOntologyMolecularFunction	lysine N-methyltransferase activity	KMT5B NSD1 KMT2A	6.49e-04	69	49	3	GO:0016278
GeneOntologyMolecularFunction	ATP-dependent activity	BPTF ATAD5 SHPRH MYO1B SMC2 ABCA8 MOV10	7.03e-04	614	49	7	GO:0140657
GeneOntologyMolecularFunction	histone methyltransferase activity	KMT5B NSD1 KMT2A	7.06e-04	71	49	3	GO:0042054
GeneOntologyMolecularFunction	histone H4 methyltransferase activity	KMT5B NSD1	7.84e-04	17	49	2	GO:0140939
GeneOntologyMolecularFunction	cytoskeletal anchor activity	ANK2 BICD1	1.57e-03	24	49	2	GO:0008093
GeneOntologyMolecularFunction	chromatin binding	KMT5B UBTF NSD1 KMT2A ZNF683 SMC2 NIPBL	2.05e-03	739	49	7	GO:0003682
GeneOntologyMolecularFunction	protein methyltransferase activity	KMT5B NSD1 KMT2A	2.07e-03	103	49	3	GO:0008276
GeneOntologyMolecularFunction	transferase activity, transferring nitrogenous groups	GAPDH ETNPPL	2.14e-03	28	49	2	GO:0016769
GeneOntologyMolecularFunction	N-methyltransferase activity	KMT5B NSD1 KMT2A	2.18e-03	105	49	3	GO:0008170
GeneOntologyMolecularFunction	histone modifying activity	BRCA2 KMT5B NSD1 KMT2A	2.38e-03	229	49	4	GO:0140993
GeneOntologyMolecularFunction	ATP-dependent activity, acting on DNA	BPTF ATAD5 SHPRH	3.74e-03	127	49	3	GO:0008094
GeneOntologyMolecularFunction	catalytic activity, acting on DNA	BPTF ATAD5 SHPRH NIPBL	3.86e-03	262	49	4	GO:0140097
GeneOntologyMolecularFunction	single-stranded DNA binding	BRCA2 HMGB2 SMC2	4.35e-03	134	49	3	GO:0003697
GeneOntologyMolecularFunction	DNA secondary structure binding	KMT2A HMGB2	4.55e-03	41	49	2	GO:0000217
GeneOntologyMolecularFunction	histone H3 methyltransferase activity	NSD1 KMT2A	5.23e-03	44	49	2	GO:0140938
GeneOntologyBiologicalProcess	protein-DNA complex organization	EPC2 BPTF BRCA2 KMT5B UBTF SHPRH NSD1 KMT2A HMGB2 LSM11 NIPBL	1.74e-05	999	49	11	GO:0071824
GeneOntologyBiologicalProcess	chromatin organization	EPC2 BPTF BRCA2 KMT5B SHPRH NSD1 KMT2A HMGB2 LSM11 NIPBL	4.00e-05	896	49	10	GO:0006325
Domain	PHD	BPTF SHPRH NSD1 KMT2A	8.66e-05	89	49	4	SM00249
Domain	Znf_PHD	BPTF SHPRH NSD1 KMT2A	9.45e-05	91	49	4	IPR001965
Domain	ZF_PHD_2	BPTF SHPRH NSD1 KMT2A	1.12e-04	95	49	4	PS50016
Domain	ZF_PHD_1	BPTF SHPRH NSD1 KMT2A	1.16e-04	96	49	4	PS01359
Domain	SET	KMT5B NSD1 KMT2A	1.69e-04	41	49	3	PF00856
Domain	SET	KMT5B NSD1 KMT2A	2.38e-04	46	49	3	SM00317
Domain	HMG_box_2	UBTF HMGB2	2.40e-04	9	49	2	PF09011
Domain	SET_dom	KMT5B NSD1 KMT2A	3.05e-04	50	49	3	IPR001214
Domain	SET	KMT5B NSD1 KMT2A	3.05e-04	50	49	3	PS50280
Domain	RRM_dom	DNAJC17 RBM27 PPIL4 RBM20 SCAF4	3.13e-04	227	49	5	IPR000504
Domain	RRM	DNAJC17 RBM27 PPIL4 RBM20 SCAF4	3.33e-04	230	49	5	PS50102
Domain	-	DNAJC17 RBM27 PPIL4 RBM20 SCAF4	4.36e-04	244	49	5	3.30.70.330
Domain	Nucleotide-bd_a/b_plait	DNAJC17 RBM27 PPIL4 RBM20 SCAF4	5.62e-04	258	49	5	IPR012677
Domain	Znf_FYVE_PHD	BPTF SHPRH NSD1 KMT2A	5.93e-04	147	49	4	IPR011011
Domain	Zinc_finger_PHD-type_CS	BPTF SHPRH NSD1	6.61e-04	65	49	3	IPR019786
Domain	Post-SET_dom	NSD1 KMT2A	7.90e-04	16	49	2	IPR003616
Domain	PostSET	NSD1 KMT2A	7.90e-04	16	49	2	SM00508
Domain	POST_SET	NSD1 KMT2A	7.90e-04	16	49	2	PS50868
Domain	PHD	BPTF NSD1 KMT2A	1.00e-03	75	49	3	PF00628
Domain	Znf_PHD-finger	BPTF NSD1 KMT2A	1.17e-03	79	49	3	IPR019787
Domain	Cyclophilin-type_PPIase	PPIL4 PPIB	1.37e-03	21	49	2	IPR024936
Domain	Cyclophilin-like_dom	PPIL4 PPIB	1.51e-03	22	49	2	IPR029000
Domain	CSA_PPIASE_2	PPIL4 PPIB	1.51e-03	22	49	2	PS50072
Domain	Pro_isomerase	PPIL4 PPIB	1.51e-03	22	49	2	PF00160
Domain	-	PPIL4 PPIB	1.51e-03	22	49	2	2.40.100.10
Domain	Cyclophilin-type_PPIase_dom	PPIL4 PPIB	1.51e-03	22	49	2	IPR002130
Domain	CSA_PPIASE_1	PPIL4 PPIB	1.51e-03	22	49	2	PS00170
Domain	RRM_1	DNAJC17 RBM27 PPIL4 SCAF4	2.14e-03	208	49	4	PF00076
Domain	RRM	RBM27 PPIL4 RBM20 SCAF4	2.49e-03	217	49	4	SM00360
Domain	BROMODOMAIN_2	BPTF KMT2A	5.18e-03	41	49	2	PS50014
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	BPTF EEF1D BRCA2 GAPDH RBM27 ATAD5 UBTF PPIL4 NSD1 CSTF3 KMT2A HMGB2 PPIB NIPBL HMGB1P1 SCAF4	2.65e-13	954	51	16	36373674
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	EPC2 BPTF EEF1D GAPDH RBM27 UBTF MAT2A CSTF3 KMT2A HMGB2 SMC2 PPIB NIPBL SCAF4	4.15e-10	1103	51	14	34189442
Pubmed	Human transcription factor protein interaction networks.	EPC2 BPTF EEF1D RBM27 ATAD5 UBTF PPIL4 KMT2A HMGB2 MYO1B REL NIPBL RBM20 MOV10 SCAF4	1.18e-09	1429	51	15	35140242
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	BPTF EEF1D DNAJC17 RBM27 ATAD5 UBTF MAT2A PPIL4 CSTF3 KMT2A HMGB2 SMC2 NIPBL	1.74e-09	1014	51	13	32416067
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	EEF1D GAPDH RBM27 UBTF MAT2A PPIL4 HMGB2 MYO1B SMC2 PPIB RASAL2 MOV10	2.03e-07	1257	51	12	36526897
Pubmed	PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry.	GAPDH RBM27 MYO1B SMC2 NIPBL MOV10 SCAF4	6.42e-07	340	51	7	24332808
Pubmed	The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.	EEF1D GAPDH RBM27 UBTF MAT2A RABGAP1L HMGB2 SMC2 PPIB HMGB1P1 MOV10	7.15e-07	1153	51	11	29845934
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	TOMM70 EEF1D GAPDH UBTF MAT2A PPIL4 CSTF3 MYO1B SMC2 PPIB NIPBL RASAL2	7.70e-07	1425	51	12	30948266
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	CREBRF BPTF EEF1D ANK2 KMT2A HMGB2 MYO1B REL SMC2 SPAG17 PPIB NIPBL	8.72e-07	1442	51	12	35575683
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	BPTF EEF1D GAPDH UBTF CSTF3 MYO1B SMC2 PPIB NIPBL SCAF4	2.00e-06	1024	51	10	24711643
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	CREBRF EEF1D GAPDH KMT5B FAM83G CSTF3 MYO1B SMC2 PPIB RASAL2 MOV10	2.04e-06	1284	51	11	17353931
Pubmed	A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.	BPTF TOMM70 LCA5L CSTF3 HMGB2 CDC25C PPIB	2.61e-06	420	51	7	28065597
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	EEF1D GAPDH UBTF MAT2A PPIL4 MYO1B SMC2 PPIB NIPBL RASAL2 MOV10	3.37e-06	1353	51	11	29467282
Pubmed	Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.	EEF1D MAT2A RABGAP1L HMGB2 SMC2 PPIB NIPBL HMGB1P1 SCAF4	3.52e-06	847	51	9	35235311
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	EEF1D GAPDH RBM27 MAT2A HMGB2 MYO1B SMC2 PPIB MOV10 SCAF4	5.55e-06	1149	51	10	35446349
Pubmed	Enhancers of Polycomb EPC1 and EPC2 sustain the oncogenic potential of MLL leukemia stem cells.	EPC2 KMT2A	6.32e-06	3	51	2	24166297
Pubmed	TNRC6 proteins modulate hepatitis C virus replication by spatially regulating the binding of miR-122/Ago2 complexes to viral RNA.	EEF1D GAPDH HMGB2 MYO1B PPIB MOV10	6.97e-06	317	51	6	30997501
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	ANK2 GAPDH RBM27 ATAD5 UBTF KMT2A MYO1B NIPBL SCAF4	7.73e-06	934	51	9	33916271
Pubmed	A comprehensive SARS-CoV-2-human protein-protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets.	TOMM70 EEF1D GAPDH MYO1B REL PPIB MOV10	8.48e-06	503	51	7	36217030
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	TOMM70 RBM27 ATAD5 NSD1 CSTF3 KMT2A LSM11 DENND2D NIPBL MOV10 SCAF4	8.81e-06	1497	51	11	31527615
Pubmed	Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.	BPTF KMT5B ATAD5 UBTF NSD1 KMT2A NIPBL	1.23e-05	533	51	7	30554943
Pubmed	Interaction network of human early embryonic transcription factors.	EPC2 BPTF TOMM70 GAPDH KMT2A NIPBL	1.24e-05	351	51	6	38297188
Pubmed	Ankyrin-B is a PI3P effector that promotes polarized α5β1-integrin recycling via recruiting RabGAP1L to early endosomes.	ANK2 RABGAP1L	1.26e-05	4	51	2	27718357
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	BPTF GAPDH RBM27 NSD1 KMT2A SMC2 SCAF4	1.49e-05	549	51	7	38280479
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	EPC2 BPTF RBM27 ATAD5 UBTF NSD1 KMT2A SMC2 NIPBL SCAF4	1.56e-05	1294	51	10	30804502
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	TOMM70 ATAD5 UBTF CSTF3 MYO1B TRIM13 CDC25C PPIB RBM20	1.94e-05	1049	51	9	27880917
Pubmed	EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.	EEF1D GAPDH MAT2A HMGB2 MYO1B SMC2 PPIB MOV10	2.06e-05	803	51	8	36517590
Pubmed	SHPRH regulates rRNA transcription by recognizing the histone code in an mTOR-dependent manner.	UBTF SHPRH	2.10e-05	5	51	2	28400511
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	RBM27 UBTF PPIL4 CSTF3 HMGB2 PPIB MOV10 SCAF4	2.14e-05	807	51	8	22681889
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	TOMM70 EEF1D GAPDH KMT2A HMGB2 MYO1B SPAG17 PPIB	2.14e-05	807	51	8	30575818
Pubmed	A systems wide mass spectrometric based linear motif screen to identify dominant in-vivo interacting proteins for the ubiquitin ligase MDM2.	GAPDH UBTF PPIB	2.23e-05	37	51	3	24583282
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	BPTF MAP2 RBM27 PPIL4 CSTF3 MYO1B PPIB NIPBL SCAF4	2.48e-05	1082	51	9	38697112
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	EEF1D ANK2 GAPDH RBM27 PPIL4 KMT2A MYO1B PPIB MOV10 SCAF4	2.56e-05	1371	51	10	36244648
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	BPTF ATAD5 UBTF SHPRH NSD1 KMT2A NIPBL	2.87e-05	608	51	7	36089195
Pubmed	Exploring an Alternative Cysteine-Reactive Chemistry to Enable Proteome-Wide PPI Analysis by Cross-Linking Mass Spectrometry.	GAPDH MAT2A HMGB2 MYO1B SMC2 RASAL2	3.02e-05	411	51	6	36652389
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	EEF1D RBM27 UBTF CSTF3 KMT2A MYO1B SMC2 MOV10	3.02e-05	847	51	8	35850772
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	EPC2 DNAJC17 RBM27 ATAD5 SHPRH KMT2A HMGB2	4.17e-05	645	51	7	25281560
Pubmed	Elevated lung cancer risk is associated with deficiencies in cell cycle checkpoints: genotype and phenotype analyses from a case-control study.	BRCA2 CDC25C	4.41e-05	7	51	2	19626602
Pubmed	Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability.	EEF1D BRCA2 GAPDH ATAD5 SMC2 PPIB NIPBL	4.46e-05	652	51	7	31180492
Pubmed	Targeted and Interactome Proteomics Revealed the Role of PHD2 in Regulating BRD4 Proline Hydroxylation.	EEF1D GAPDH UBTF MAT2A PPIL4 SMC2	4.47e-05	441	51	6	31239290
Pubmed	Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.	EEF1D RBM27 PPIL4 CSTF3 SMC2 MOV10 SCAF4	4.50e-05	653	51	7	33742100
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	BPTF UBTF NSD1 KMT2A MYO1B NIPBL MOV10	4.50e-05	653	51	7	22586326
Pubmed	Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice.	KMT5B NSD1 KMT2A	5.22e-05	49	51	3	34368113
Pubmed	TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions.	EEF1D GAPDH CSTF3 HMGB2 REL PPIB MOV10 SCAF4	5.49e-05	922	51	8	27609421
Pubmed	The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition.	EEF1D MAP2 CSTF3 KMT2A PPIB	5.76e-05	281	51	5	24163370
Pubmed	A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.	BPTF BRCA2 UBTF MOV10	6.39e-05	146	51	4	23892456
Pubmed	A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.	BPTF DNAJC17 CSTF3 SMC2 PPIB SCAF4	6.50e-05	472	51	6	38943005
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	ANK2 GAPDH MAT2A MYO1B SMC2 PPIB RASAL2	7.48e-05	708	51	7	39231216
Pubmed	BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.	TOMM70 EEF1D GAPDH MAT2A KMT2A HMGB2 PPIB	7.68e-05	711	51	7	33022573
Pubmed	New nomenclature for chromatin-modifying enzymes.	KMT5B NSD1 KMT2A	8.22e-05	57	51	3	18022353
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	MAP2 UBTF SHPRH KMT2A PPIB SCAF4	8.63e-05	497	51	6	36774506
Pubmed	A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart.	ANK2 MAP2 GAPDH	9.58e-05	60	51	3	19075228
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	EEF1D GAPDH RBM27 MAT2A KMT2A SMC2 PPIB NIPBL MOV10	1.14e-04	1318	51	9	30463901
Pubmed	Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.	CREBRF BPTF MAT2A RABGAP1L NIPBL SCAF4	1.30e-04	536	51	6	15840001
Pubmed	Exchangeable gene trap using the Cre/mutated lox system.	CREBRF BPTF MAT2A RABGAP1L NIPBL SCAF4	1.33e-04	538	51	6	10512203
Pubmed	MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.	EPC2 RBM27 UBTF KMT2A SCAF4	1.39e-04	339	51	5	30415952
Pubmed	TIF1γ inhibits lung adenocarcinoma EMT and metastasis by interacting with the TAF15/TBP complex.	BPTF TOMM70 RBM27 SMC2	1.40e-04	179	51	4	36261009
Pubmed	A Map of Human Mitochondrial Protein Interactions Linked to Neurodegeneration Reveals New Mechanisms of Redox Homeostasis and NF-κB Signaling.	BPTF EEF1D GAPDH RBM27 MAT2A CSTF3 MYO1B	1.43e-04	786	51	7	29128334
Pubmed	Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.	MYO1B SPAG17 AIM2 NIPBL HMGB1P1 RASAL2 BICD1	1.77e-04	814	51	7	23251661
Pubmed	A comprehensive resource of interacting protein regions for refining human transcription factor networks.	EEF1D ANK2 MAP2 UBTF	1.80e-04	191	51	4	20195357
Pubmed	An efficient method for generation of bi-allelic null mutant mouse embryonic stem cells and its application for investigating epigenetic modifiers.	EPC2 KMT5B	1.90e-04	14	51	2	28981838
Pubmed	In vitro nuclear interactome of the HIV-1 Tat protein.	EEF1D UBTF KMT2A SMC2	1.95e-04	195	51	4	19454010
Pubmed	Enzymatic nucleosome acetylation selectively affects activity of histone methyltransferases in vitro.	KMT5B KMT2A	2.19e-04	15	51	2	35907431
Pubmed	Uncovering a mammalian neural-specific poly(A) binding protein with unique properties.	MAP2 GAPDH	2.19e-04	15	51	2	37704377
Pubmed	A signature motif in LIM proteins mediates binding to checkpoint proteins and increases tumour radiosensitivity.	KMT2A CDC25C	2.19e-04	15	51	2	28094252
Pubmed	Host cell interactome of HIV-1 Rev includes RNA helicases involved in multiple facets of virus production.	GAPDH CSTF3 PPIB NIPBL	2.40e-04	206	51	4	22174317
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	EPC2 BPTF TOMM70 EEF1D REL SMC2 MOV10	2.43e-04	857	51	7	25609649
Pubmed	Interaction of Deubiquitinase 2A-DUB/MYSM1 with DNA Repair and Replication Factors.	UBTF PPIB	2.50e-04	16	51	2	32466590
Pubmed	Involvement of the TRAP220 component of the TRAP/SMCC coactivator complex in embryonic development and thyroid hormone action.	MAP2 GAPDH	2.50e-04	16	51	2	10882104
Pubmed	Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.	BPTF NSD1 NIPBL	2.51e-04	83	51	3	28794006
Pubmed	WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.	RBM27 ATAD5 SHPRH KMT2A HMGB2	2.78e-04	394	51	5	27248496
Pubmed	The ubiquitin ligase Uhrf2 is a master regulator of cholesterol biosynthesis and is essential for liver regeneration.	BPTF KMT2A NIPBL	2.79e-04	86	51	3	37253089
Pubmed	Screening E3 substrates using a live phage display library.	MAP2 UBTF	2.83e-04	17	51	2	24124579
Pubmed	Network organization of the huntingtin proteomic interactome in mammalian brain.	TOMM70 BRCA2 MAP2 GAPDH SMC2 PPIB	2.88e-04	621	51	6	22794259
Pubmed	The leukemogenic AF4-MLL fusion protein causes P-TEFb kinase activation and altered epigenetic signatures.	NSD1 KMT2A	3.18e-04	18	51	2	21030982
Pubmed	Wilms Tumor Predisposition	BRCA2 NSD1	3.18e-04	18	51	2	20301471
Pubmed	Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.	BRCA2 UBTF PPIL4 NIPBL	3.19e-04	222	51	4	37071664
Pubmed	Suppression of ACE2 SUMOylation protects against SARS-CoV-2 infection through TOLLIP-mediated selective autophagy.	EEF1D GAPDH UBTF MAT2A PPIL4 SMC2	3.41e-04	641	51	6	36057605
Pubmed	Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways.	EEF1D REL TRIM13	3.62e-04	94	51	3	12761501
Pubmed	Nucleolar proteome dynamics.	GAPDH UBTF SMC2 PPIB NIPBL	3.69e-04	419	51	5	15635413
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	EEF1D UBTF NSD1 MYO1B	3.89e-04	234	51	4	36243803
Pubmed	Proteomic Analysis of the EWS-Fli-1 Interactome Reveals the Role of the Lysosome in EWS-Fli-1 Turnover.	GAPDH UBTF KMT2A PPIB NIPBL	3.94e-04	425	51	5	24999758
Pubmed	USP45 and Spindly are part of the same complex implicated in cell migration.	EEF1D CPNE9 GAPDH SMC2	3.96e-04	235	51	4	30258100
Pubmed	Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells.	TOMM70 EEF1D MAT2A HMGB2 MYO1B SMC2	4.14e-04	665	51	6	30457570
Pubmed	Nde1 is required for heterochromatin compaction and stability in neocortical neurons.	GAPDH UBTF	4.35e-04	21	51	2	35601919
Pubmed	An Alternative Splicing Program for Mouse Craniofacial Development.	MAP2 MYO1B	4.35e-04	21	51	2	33013468
Pubmed	Characterization of staufen1 ribonucleoproteins by mass spectrometry and biochemical analyses reveal the presence of diverse host proteins associated with human immunodeficiency virus type 1.	TOMM70 EEF1D GAPDH MOV10	4.35e-04	241	51	4	23125841
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	EEF1D GAPDH UBTF MAT2A MYO1B PPIB MOV10	4.48e-04	949	51	7	36574265
Pubmed	Profiling the interactome of protein kinase C ζ by proteomics and bioinformatics.	EEF1D GAPDH PPIL4	5.01e-04	105	51	3	29491746
Pubmed	MRG15 binds directly to PALB2 and stimulates homology-directed repair of chromosomal breaks.	EPC2 BRCA2	5.23e-04	23	51	2	20332121
Pubmed	ATG5 is required for B cell polarization and presentation of particulate antigens.	EEF1D RBM27 UBTF MAT2A CSTF3 SMC2	5.47e-04	701	51	6	30196744
Pubmed	Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome.	TOMM70 GAPDH UBTF PPIB	5.70e-04	259	51	4	9811942
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	BPTF EEF1D GAPDH RBM27 UBTF PPIL4 MYO1B	5.73e-04	989	51	7	36424410
Pubmed	Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15.	EEF1D GAPDH MAT2A PPIL4 PPIB MOV10	6.02e-04	714	51	6	28302793
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	BPTF UBTF KMT2A SMC2 MOV10	6.15e-04	469	51	5	27634302
Pubmed	Symmetric neural progenitor divisions require chromatin-mediated homologous recombination DNA repair by Ino80.	BRCA2 MAP2	6.19e-04	25	51	2	32737294
Pubmed	The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation.	EEF1D DNAJC17 RBM27 HMGB2 CDC25C PPIB MOV10	6.37e-04	1007	51	7	34597346
Pubmed	PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation.	GAPDH RBM27 MYO1B PPIB MOV10	6.64e-04	477	51	5	31300519
Pubmed	Apurinic endonuclease-1 preserves neural genome integrity to maintain homeostasis and thermoregulation and prevent brain tumors.	BRCA2 MAP2	6.70e-04	26	51	2	30538199
Pubmed	Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.	BPTF EEF1D ANK2 SMC2	6.76e-04	271	51	4	32433965
Interaction	SMC5 interactions	BPTF EEF1D BRCA2 GAPDH RBM27 ATAD5 UBTF PPIL4 NSD1 CSTF3 KMT2A HMGB2 PPIB NIPBL HMGB1P1 SCAF4	1.67e-09	1000	51	16	int:SMC5
Interaction	H3C1 interactions	BPTF DNAJC17 ANK2 GAPDH ATAD5 UBTF SHPRH NSD1 CSTF3 KMT2A HMGB2 NIPBL MOV10	2.57e-07	901	51	13	int:H3C1
Interaction	H3C15 interactions	ANK2 GAPDH UBTF PPIL4 KMT2A HMGB2 MYO1B	8.60e-07	207	51	7	int:H3C15
Interaction	CEBPA interactions	EPC2 BPTF EEF1D GAPDH RBM27 UBTF MAT2A CSTF3 KMT2A HMGB2 SMC2 PPIB NIPBL SCAF4	1.64e-06	1245	51	14	int:CEBPA
Interaction	CIT interactions	BPTF EEF1D GAPDH RBM27 UBTF MAT2A PPIL4 CSTF3 KMT2A MYO1B SPAG17 PPIB NIPBL RASAL2 BICD1	1.79e-06	1450	51	15	int:CIT
Interaction	POLR1G interactions	BPTF ATAD5 UBTF PPIL4 NSD1 KMT2A HMGB2 REL NIPBL	3.33e-06	489	51	9	int:POLR1G
Interaction	SNRNP40 interactions	DNAJC17 BRCA2 GAPDH ATAD5 UBTF CSTF3 KMT2A RBM20 MOV10 SCAF4	3.68e-06	637	51	10	int:SNRNP40
Interaction	CENPA interactions	BPTF ATAD5 UBTF SHPRH NSD1 KMT2A HMGB2 NIPBL	4.39e-06	377	51	8	int:CENPA
Interaction	EP300 interactions	EEF1D BRCA2 GAPDH RBM27 UBTF PPIL4 CSTF3 HMGB2 REL SMC2 CDC25C HMGB1P1 MOV10 SCAF4	6.50e-06	1401	51	14	int:EP300
Interaction	H2BC21 interactions	EPC2 BPTF TOMM70 ATAD5 SHPRH NSD1 KMT2A SMC2 NIPBL SCAF4	8.03e-06	696	51	10	int:H2BC21
Interaction	TERF2IP interactions	BPTF BRCA2 RBM27 ATAD5 UBTF PPIL4 NSD1 KMT2A NIPBL	8.87e-06	552	51	9	int:TERF2IP
Interaction	EED interactions	EPC2 BPTF TOMM70 EEF1D GAPDH SHPRH NSD1 HMGB2 MYO1B SMC2 PPIB NIPBL MOV10 SCAF4	9.27e-06	1445	51	14	int:EED
Interaction	H2BC8 interactions	EPC2 BPTF DNAJC17 ATAD5 UBTF NSD1 KMT2A HMGB2 NIPBL	1.25e-05	576	51	9	int:H2BC8
Interaction	MIEN1 interactions	HMGB2 REL MOV10	1.69e-05	20	51	3	int:MIEN1
Interaction	CCDC38 interactions	GAPDH PPIB	3.76e-05	4	51	2	int:CCDC38
Interaction	CHEK2 interactions	EEF1D BRCA2 ATAD5 MYO1B SMC2 CDC25C	3.87e-05	250	51	6	int:CHEK2
Interaction	NADK interactions	CDC25C RASAL2 MOV10 BICD1	4.99e-05	80	51	4	int:NADK
Interaction	SQSTM1 interactions	BPTF EEF1D MAT2A CSTF3 HMGB2 MYO1B REL TRIM13 AIM2 NIPBL MOV10 BICD1	5.38e-05	1257	51	12	int:SQSTM1
Interaction	PARP1 interactions	BPTF BRCA2 GAPDH ATAD5 UBTF MAT2A SHPRH NSD1 HMGB2 SMC2 NIPBL MOV10	8.38e-05	1316	51	12	int:PARP1
Interaction	CELF1 interactions	RBM27 PPIL4 CSTF3 RBM20 MOV10 SCAF4	8.48e-05	288	51	6	int:CELF1
Interaction	SHPRH interactions	BPTF UBTF SHPRH PPIB	1.06e-04	97	51	4	int:SHPRH
Interaction	ZNF330 interactions	ATAD5 UBTF SHPRH NSD1 KMT2A ZNF683 NIPBL	1.24e-04	446	51	7	int:ZNF330
Interaction	CDK2 interactions	EEF1D BRCA2 GAPDH UBTF HMGB2 MYO1B REL CDC25C PPIB	1.35e-04	783	51	9	int:CDK2
Interaction	AR interactions	GAPDH RBM27 UBTF NSD1 CSTF3 KMT2A HMGB2 MYO1B REL NIPBL	1.62e-04	992	51	10	int:AR
Interaction	PCF11 interactions	DNAJC17 GAPDH RBM27 MOV10	1.78e-04	111	51	4	int:PCF11
Interaction	FLNA interactions	BRCA2 GAPDH HMGB2 MYO1B REL CDC25C PPIB NIPBL	2.05e-04	648	51	8	int:FLNA
Interaction	PPIB interactions	GAPDH SHPRH HMGB2 PPIB NIPBL MOV10	2.27e-04	345	51	6	int:PPIB
Interaction	POLR1A interactions	UBTF SHPRH REL PPIB MOV10	2.31e-04	220	51	5	int:POLR1A
Interaction	BRD3 interactions	BPTF KMT5B ATAD5 UBTF NSD1 KMT2A NIPBL	2.32e-04	494	51	7	int:BRD3
Interaction	H3C3 interactions	BPTF ATAD5 UBTF SHPRH NSD1 KMT2A NIPBL	2.35e-04	495	51	7	int:H3C3
Interaction	PCNA interactions	BRCA2 GAPDH ATAD5 SHPRH CDC25C PPIB NIPBL	2.41e-04	497	51	7	int:PCNA
Interaction	POLR1E interactions	BRCA2 ATAD5 UBTF NSD1 KMT2A REL	2.45e-04	350	51	6	int:POLR1E
Interaction	CCNE1 interactions	BRCA2 UBTF REL CDC25C	2.48e-04	121	51	4	int:CCNE1
Interaction	MED8 interactions	GAPDH KMT2A MOV10 SCAF4	2.48e-04	121	51	4	int:MED8
Interaction	RBBP7 interactions	BPTF BRCA2 GAPDH SHPRH KMT2A SMC2 AIM2	2.72e-04	507	51	7	int:RBBP7
Interaction	KLF3 interactions	EPC2 BPTF TOMM70 KMT2A NIPBL	2.73e-04	228	51	5	int:KLF3
Interaction	PAPOLB interactions	GAPDH CSTF3	2.79e-04	10	51	2	int:PAPOLB
Interaction	CLHC1 interactions	BRCA2 MOV10	2.79e-04	10	51	2	int:CLHC1
Interaction	CDK9 interactions	EEF1D BRCA2 GAPDH RBM27 PPIL4 CSTF3 KMT2A SMC2	2.99e-04	685	51	8	int:CDK9
Interaction	KCNA3 interactions	ANK2 GAPDH UBTF MAT2A KMT2A MYO1B SMC2 PPIB RASAL2	3.00e-04	871	51	9	int:KCNA3
Interaction	MECP2 interactions	BPTF MAP2 RBM27 PPIL4 NSD1 CSTF3 MYO1B AIM2 PPIB NIPBL SCAF4	3.08e-04	1287	51	11	int:MECP2
Interaction	TLE3 interactions	BRCA2 KMT2A MYO1B NIPBL RBM20 SCAF4	3.59e-04	376	51	6	int:TLE3
Interaction	BAP1 interactions	EEF1D BRCA2 GAPDH RBM27 MAT2A HMGB2 MYO1B SMC2 PPIB MOV10 SCAF4	3.67e-04	1314	51	11	int:BAP1
Interaction	POLR2A interactions	EEF1D BRCA2 NSD1 CSTF3 KMT2A MOV10 SCAF4	3.80e-04	536	51	7	int:POLR2A
Interaction	CFAP97 interactions	HMGB2 MOV10 BICD1	4.06e-04	57	51	3	int:CFAP97
Interaction	ZFY interactions	NSD1 PPIB	4.08e-04	12	51	2	int:ZFY
Interaction	DHX40 interactions	RBM27 UBTF PPIL4 NSD1 RBM20	4.09e-04	249	51	5	int:DHX40
Interaction	BIRC3 interactions	TOMM70 EEF1D GAPDH UBTF MAT2A CSTF3 MYO1B REL SMC2 PPIB RASAL2	4.18e-04	1334	51	11	int:BIRC3
Interaction	HEXIM1 interactions	EEF1D GAPDH RBM27 RABGAP1L PPIL4 HMGB2 SMC2 PPIB MOV10	4.23e-04	913	51	9	int:HEXIM1
Interaction	KLHL40 interactions	BRCA2 GAPDH REL	4.49e-04	59	51	3	int:KLHL40
Interaction	COIL interactions	UBTF PPIL4 NSD1 HMGB2 LSM11 DENND2D NIPBL	4.53e-04	552	51	7	int:COIL
Interaction	H2BC4 interactions	TOMM70 GAPDH PPIL4 KMT2A SPAG17	4.89e-04	259	51	5	int:H2BC4
Interaction	ARHGEF4 interactions	PPIL4 PPIB MOV10	4.95e-04	61	51	3	int:ARHGEF4
Interaction	AGR2 interactions	TOMM70 EEF1D GAPDH NSD1 KMT2A HMGB2 MYO1B SPAG17 PPIB	4.99e-04	934	51	9	int:AGR2
Interaction	RFXANK interactions	BPTF BRCA2 SMC2 MOV10	5.07e-04	146	51	4	int:RFXANK
Interaction	GIGYF2 interactions	MYO1B SMC2 CDC25C RASAL2 BICD1	5.24e-04	263	51	5	int:GIGYF2
Interaction	H3-3A interactions	BPTF ATAD5 UBTF SHPRH NSD1 KMT2A HMGB2 NIPBL	5.42e-04	749	51	8	int:H3-3A
Interaction	CALD1 interactions	EEF1D GAPDH KMT2A MYO1B BICD1	5.43e-04	265	51	5	int:CALD1
Interaction	ATRX interactions	ANK2 RBM27 NSD1 CSTF3 SMC2	5.61e-04	267	51	5	int:ATRX
Interaction	RAD52 interactions	EEF1D BRCA2 GAPDH	5.71e-04	64	51	3	int:RAD52
Interaction	EEF1B2 interactions	EEF1D NSD1 HMGB2 AIM2 MOV10	5.71e-04	268	51	5	int:EEF1B2
Interaction	CHD3 interactions	BPTF GAPDH ATAD5 UBTF SHPRH KMT2A MYO1B MOV10	5.81e-04	757	51	8	int:CHD3
Interaction	CKB interactions	KMT2A HMGB2 PPIB MOV10 BICD1	5.91e-04	270	51	5	int:CKB
Interaction	PPP5C interactions	MAP2 GAPDH RABGAP1L PPIB MOV10	6.11e-04	272	51	5	int:PPP5C
Interaction	HMGA1 interactions	CNBD1 BRCA2 NSD1 KMT2A HMGB2 HMGB1P1	6.36e-04	419	51	6	int:HMGA1
Interaction	C3orf49 interactions	BPTF UBTF	6.46e-04	15	51	2	int:C3orf49
Interaction	NPR2 interactions	BRCA2 MOV10	6.46e-04	15	51	2	int:NPR2
Interaction	SUMO2 interactions	BPTF GAPDH SMC2 PPIB NIPBL ABCA8 HMGB1P1	6.80e-04	591	51	7	int:SUMO2
Interaction	NAA40 interactions	ANK2 GAPDH RBM27 ATAD5 UBTF KMT2A MYO1B NIPBL SCAF4	6.96e-04	978	51	9	int:NAA40
Interaction	BRD2 interactions	BPTF DNAJC17 KMT5B ATAD5 UBTF DENND2D	7.20e-04	429	51	6	int:BRD2
Interaction	LIMA1 interactions	EEF1D GAPDH MYO1B CDC25C RASAL2 MOV10	7.20e-04	429	51	6	int:LIMA1
Interaction	USP21 interactions	BRCA2 AIM2 PPIB RASAL2	7.32e-04	161	51	4	int:USP21
Interaction	GREB1L interactions	BRCA2 MOV10	7.37e-04	16	51	2	int:GREB1L
Interaction	OBSCN interactions	ANK2 GAPDH MOV10	7.42e-04	70	51	3	int:OBSCN
Interaction	CEBPB interactions	BPTF TOMM70 EEF1D BRCA2 GAPDH UBTF MAT2A HMGB2 SMC2 PPIB SCAF4	8.09e-04	1443	51	11	int:CEBPB
Cytoband	1q24	RABGAP1L RASAL2	2.27e-04	20	51	2	1q24
Cytoband	9q31.1	OR13C3 SMC2	9.65e-04	41	51	2	9q31.1
GeneFamily	PHD finger proteins	BPTF SHPRH NSD1 KMT2A	1.63e-05	90	31	4	88
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	KMT5B NSD1 KMT2A	2.63e-05	34	31	3	487
GeneFamily	RNA binding motif containing	DNAJC17 RBM27 PPIL4 RBM20 SCAF4	2.87e-05	213	31	5	725
GeneFamily	Cyclophilin peptidylprolyl isomerases	PPIL4 PPIB	4.78e-04	19	31	2	909
Coexpression	GSE14415_NATURAL_TREG_VS_FOXP3_KO_NATURAL_TREG_DN	EPC2 BPTF ZFP90 KMT5B PPIL4 AIM2	6.93e-07	164	50	6	M2972
Coexpression	GSE44649_NAIVE_VS_ACTIVATED_CD8_TCELL_MIR155_KO_DN	KMT5B ATAD5 SHPRH REL CDC25C RASAL2	2.20e-06	200	50	6	M9777
Coexpression	TRAVAGLINI_LUNG_PROLIFERATING_NK_T_CELL	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	4.74e-06	129	50	5	M41687
Coexpression	EGUCHI_CELL_CYCLE_RB1_TARGETS	HMGB2 SMC2 CDC25C	9.80e-06	22	50	3	M4455
Coexpression	FAN_EMBRYONIC_CTX_MICROGLIA_1	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	1.16e-05	155	50	5	M39041
Coexpression	GSE11386_NAIVE_VS_MEMORY_BCELL_DN	KMT5B RABGAP1L NSD1 REL NIPBL	1.27e-05	158	50	5	M372
Coexpression	BUSSLINGER_GASTRIC_IMMUNE_CELLS	CREBRF BPTF EEF1D GAPDH RBM27 UBTF RABGAP1L NSD1 KMT2A ZNF683 DENND2D NIPBL	1.78e-05	1492	50	12	M40023
Coexpression	GSE13547_CTRL_VS_ANTI_IGM_STIM_BCELL_12H_UP	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	2.86e-05	187	50	5	M2984
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HPROGFPL	EEF1D BRCA2 ATAD5 HMGB2 SMC2 CDC25C	3.31e-05	322	50	6	M39060
Coexpression	GSE4142_PLASMA_CELL_VS_MEMORY_BCELL_UP	CPNE9 GAPDH ETNPPL RASAL2 BICD1	3.85e-05	199	50	5	M6395
Coexpression	GSE22886_UNSTIM_VS_STIM_MEMORY_TCELL_DN	TOMM70 ATAD5 MAT2A HMGB2 MYO1B	3.94e-05	200	50	5	M4410
Coexpression	GSE39820_CTRL_VS_TGFBETA3_IL6_IL23A_CD4_TCELL_UP	RBM27 ATAD5 MAT2A RABGAP1L SHPRH	3.94e-05	200	50	5	M5613
Coexpression	KREPPEL_CD99_TARGETS_DN	RABGAP1L KMT2A	7.44e-05	7	50	2	M1269
Coexpression	PUJANA_BRCA_CENTERED_NETWORK	BRCA2 MAT2A HMGB2 SMC2	7.66e-05	118	50	4	M15305
Coexpression	MARKEY_RB1_ACUTE_LOF_UP	BRCA2 HMGB2 SMC2 CDC25C NIPBL	8.81e-05	237	50	5	M15606
Coexpression	MARIADASON_RESPONSE_TO_BUTYRATE_SULINDAC_6	KMT5B HMGB2 SMC2	9.98e-05	47	50	3	M1652
Coexpression	HOFFMANN_LARGE_TO_SMALL_PRE_BII_LYMPHOCYTE_UP	BRCA2 HMGB2 SMC2 CDC25C	2.09e-04	153	50	4	M5588
Coexpression	GENTILE_UV_HIGH_DOSE_DN	UBTF MAT2A CSTF3 HMGB2 TRIM13	2.22e-04	289	50	5	M13630
Coexpression	SHEDDEN_LUNG_CANCER_POOR_SURVIVAL_A6	BRCA2 GAPDH HMGB2 SMC2 CDC25C RASAL2	2.28e-04	458	50	6	M8520
CoexpressionAtlas	facebase_RNAseq_e10.5_NeuroEpith_central_2500_K4	CREBRF EPC2 BPTF ANK2 BRCA2 MAP2 ATAD5 LCA5L NSD1 HMGB2 SMC2 CDC25C NIPBL RASAL2 BICD1	3.40e-07	1370	50	15	facebase_RNAseq_e10.5_NeuroEpith_central_2500_K4
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_LatNas_2500	EPC2 BPTF ANK2 BRCA2 MAP2 RBM27 ATAD5 NSD1 HMGB2 SMC2 CDC25C NIPBL BICD1	2.32e-05	1459	50	13	facebase_RNAseq_e10.5_Emin_LatNas_2500
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_LatNas_2500_K3	EPC2 BPTF ANK2 BRCA2 RBM27 ATAD5 NSD1 HMGB2 SMC2 CDC25C NIPBL BICD1	2.61e-05	1257	50	12	facebase_RNAseq_e10.5_Emin_LatNas_2500_K3
CoexpressionAtlas	FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_2500_k-means-cluster#1	CPNE9 BRCA2 ATAD5 HMGB2 SMC2 CDC25C NIPBL	1.08e-04	469	50	7	Facebase_RNAseq_e8.5_Floor Plate_2500_K1
ToppCell	LPS_only-Endothelial-Endothelial-FOXM1\|LPS_only / Treatment groups by lineage, cell group, cell type	BRCA2 ATAD5 CSTF3 HMGB2 SMC2 CDC25C	8.84e-08	197	50	6	038fd92750257d43d5e980fd06d77742b543f11a
ToppCell	10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-Prolif_T\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	BRCA2 GAPDH ATAD5 HMGB2 SMC2 CDC25C	9.11e-08	198	50	6	48d39018c56ea8ba972c72af8ece10cbeb48fbc8
ToppCell	normal_Lung-T/NK_cells-Undetermined\|T/NK_cells / Location, Cell class and cell subclass	BRCA2 GAPDH ATAD5 HMGB2 SMC2 CDC25C	9.38e-08	199	50	6	4142d5b1b20212508f95841fdac4efb7655616cb
ToppCell	Non-neuronal-Dividing-IPC-IPC-div2\|World / Primary Cells by Cluster	EEF1D BRCA2 GAPDH ATAD5 HMGB2 SMC2	9.66e-08	200	50	6	4923d7a4f00853c4d76fc1cc0fa82d522a2302e7
ToppCell	Non-neuronal-Dividing-IPC\|World / Primary Cells by Cluster	EEF1D BRCA2 ATAD5 HMGB2 SMC2 CDC25C	9.66e-08	200	50	6	971533181daa1bfac1f1b8c507d2013f891f9078
ToppCell	Non-neuronal-Dividing-IPC-IPC-div2-5\|World / Primary Cells by Cluster	EEF1D BRCA2 GAPDH ATAD5 HMGB2 SMC2	9.66e-08	200	50	6	dc1c1506823eaa105f1532c6b5d4efa14e788314
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-FOXM1\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	1.30e-06	169	50	5	e0607af8ae8609d43e26ff2a2cab92650bfcd5b7
ToppCell	LPS-IL1RA-Endothelial-Endothelial-FOXM1\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	1.78e-06	180	50	5	334e2b1f6eb7d4ece20b1c7b02107863f913237f
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-cycling_ENCC/glia\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GAPDH HMGB2 SMC2 CDC25C ABCA8	1.82e-06	181	50	5	f2ebeb4941510c4b6e50f2379c574d1778d6ced1
ToppCell	10x5'-Liver-Lymphocytic_T_CD4/8-lo-Cycling_T\|Liver / Manually curated celltypes from each tissue	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	1.87e-06	182	50	5	81557cdc88777f3bd4e1dd18a760b08fc29122ef
ToppCell	10x5'-bone_marrow-Lymphocytic_T_CD4/8-lo-Cycling_T\|bone_marrow / Manually curated celltypes from each tissue	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	1.93e-06	183	50	5	a48a6313f2f144586951cece97ec31f6d72361df
ToppCell	10x_3'_v3-spleen_(10x_3'_v3)-lymphocytic-T_lymphocytic-CD8-positive,_alpha-beta_T_cell\|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	2.03e-06	185	50	5	9d424a8608b339dd6129c58d87626678d4ec4af7
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	BRCA2 ATAD5 HMGB2 ZNF683 CDC25C	2.14e-06	187	50	5	73931a5ea73799095daff100b5f18853c57c74dc
ToppCell	10x5'-Liver-Lymphocytic_NK-Cycling_NK\|Liver / Manually curated celltypes from each tissue	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	2.20e-06	188	50	5	5eb94e652a734c6f15c68a178e9d05f0febcf34c
ToppCell	Dividing_Macrophages-SSc-ILD_02\|World / lung cells shred on cell class, cell subclass, sample id	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	2.25e-06	189	50	5	d4e88a3e50499d683e3db38aee04490146fe30bb
ToppCell	Control-Endothelial-Endothelial-FOXM1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	2.25e-06	189	50	5	1e1499b062d9c647c8f38b0c4e0d871d159be5dd
ToppCell	3'_v3-bone_marrow-Lymphocytic_T_CD4/8-lo-Cycling_T\|bone_marrow / Manually curated celltypes from each tissue	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	2.37e-06	191	50	5	210a0f1a71df2508cbfc73d6868a2122338b9a1c
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_T_CD4/8-lo-Cycling_T\|GI_small-bowel / Manually curated celltypes from each tissue	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	2.37e-06	191	50	5	e642fa7395c05fb53324c9d46bbc52f89fc9673f
ToppCell	COVID-19-kidney-Proliferating_T_cell\|COVID-19 / Disease (COVID-19 only), tissue and cell type	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	2.37e-06	191	50	5	bae388e0e9447d576e68465d73d8313ef6925ffa
ToppCell	Mild-T/NK_proliferative\|World / Disease group and Cell class	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	2.37e-06	191	50	5	9dba5526fd5ea8065ad305feb2ee562335f887c6
ToppCell	PBMC-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	2.56e-06	194	50	5	f39a471293ecc5c5967b00e772b8f48ebc9affbe
ToppCell	Control-Lymphoid_T/NK-T/NK_proliferative\|Control / Disease group, lineage and cell class	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	2.56e-06	194	50	5	9bbb124001fba7450f4639f47f9b720a483e7242
ToppCell	Control-Lymphocyte-T_NK-T_NK_proliferative\|Control / Disease, Lineage and Cell Type	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	2.56e-06	194	50	5	844731b7943d1cfca819b7b89e4e62067bfa0230
ToppCell	PBMC-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	2.56e-06	194	50	5	a75ecd0b0a928d4646602f7d16a645f6b3df3af5
ToppCell	PBMC-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	2.56e-06	194	50	5	17744fd6645cf5a447a01a83f07e8d305c2bcd9c
ToppCell	(7)_Epithelial_cells-(7)_Epithelial-J_(AT1-AT2_progenitors)\|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	2.56e-06	194	50	5	4d6ae2b25db11a4ae6dadee83be5c8c05b1225c3
ToppCell	PBMC-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	2.56e-06	194	50	5	e14f66f7584909621b776292fbd52808273fd2ee
ToppCell	COVID-19-T_cells-Cycling_NK/T_cells\|COVID-19 / group, cell type (main and fine annotations)	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	2.63e-06	195	50	5	764ed100c28d9bc93ee5ecabc5291c8f184d78da
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_cycling\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	2.63e-06	195	50	5	926eb3fc5d028be936885bea0654a77db3107234
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	2.63e-06	195	50	5	1a5e814e12fe37287dbfc58189e1958e2c76b5da
ToppCell	cycling_basal_cell\|World / shred by cell class for nasal brushing	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	2.69e-06	196	50	5	aa7bac70a2fe4a3cb28d89fa1a87c68c2ead1349
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	2.69e-06	196	50	5	1964c5003a0cb84539850a7cfe3bbb0e23a61d2d
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_cycling\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	2.69e-06	196	50	5	73f951f7712e0aa3323676b9a4b7944d21d347c4
ToppCell	Healthy-T/NK_proliferative\|World / disease group, cell group and cell class	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	2.76e-06	197	50	5	e90be1e7e02f736b6aab14010a912b592d6f1e80
ToppCell	proximal-Hematologic-Proliferating_Macrophage\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CPNE9 BRCA2 ATAD5 SMC2 CDC25C	2.76e-06	197	50	5	0b1fa881abbfcc54b322fc27124db3f8947af016
ToppCell	proximal-3-Hematologic-Proliferating_Macrophage\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CPNE9 BRCA2 ATAD5 SMC2 CDC25C	2.76e-06	197	50	5	0dd9058aa19d1268ebba9a65555870224b5a5978
ToppCell	10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-Prolif_T-Z\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	BRCA2 GAPDH HMGB2 SMC2 CDC25C	2.76e-06	197	50	5	47be19f595135da248469b2e21b8d88f561827b2
ToppCell	proximal-Hematologic-Proliferating_Macrophage-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CPNE9 BRCA2 ATAD5 SMC2 CDC25C	2.76e-06	197	50	5	9243617b307acf3df40d93c41cd8d4788699a7ea
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_NK-Cycling_NK\|lymph-node_spleen / Manually curated celltypes from each tissue	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	2.83e-06	198	50	5	b2868a897dd96494cf1829c30e0ce508f52efdf3
ToppCell	normal_Lung-T/NK_cells-Undetermined\|normal_Lung / Location, Cell class and cell subclass	GAPDH ATAD5 HMGB2 SMC2 CDC25C	2.83e-06	198	50	5	c65cdb54409087014125a76627e5efb5fe8dabc9
ToppCell	cycling_basal_cell\|World / shred by cell class for turbinate	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	2.83e-06	198	50	5	e86c1224f5b0890a50a25257628e90c790aae7cd
ToppCell	(0)_NK_dividing\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	2.83e-06	198	50	5	c5336d9b802393d6fd6f8446ea4bb6befeb97bfd
ToppCell	10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-Prolif_T-F_2\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	BRCA2 GAPDH ATAD5 HMGB2 SMC2	2.83e-06	198	50	5	bcfe7b6d91f2e2f145cb2660b65fd2a6c1134b86
ToppCell	10x5'-Lung-Myeloid_Mac-Cycling_Myeloid-Mac\|Lung / Manually curated celltypes from each tissue	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	2.90e-06	199	50	5	dee1cf8ee850a2bd57349418a9bcc0948fe9ac9e
ToppCell	3'_v3-bone_marrow-Lymphocytic_NK-Cycling_NK\|bone_marrow / Manually curated celltypes from each tissue	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	2.90e-06	199	50	5	6321140a1ebc1ff793fb6221a31e884368e42fa5
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	2.90e-06	199	50	5	4af38f5e9d2229d64f7ecdf9c00b4d67e5f86a51
ToppCell	normal_Pleural_Fluid-T/NK_cells-Undetermined\|T/NK_cells / Location, Cell class and cell subclass	GAPDH ATAD5 HMGB2 SMC2 CDC25C	2.90e-06	199	50	5	a0c20b97cb38e493b47a06e9501fc165a78c61b2
ToppCell	Dividing_Macrophages\|World / lung cells shred on cell class, cell subclass, sample id	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	2.90e-06	199	50	5	5c755b6876e164dc847ef7c723f850f227cf3a87
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-FOXM1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	2.90e-06	199	50	5	98575fcce726589e93fbb4df1aab03e57cb56076
ToppCell	LPS_IL1RA-Endothelial-Endothelial-FOXM1\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	2.90e-06	199	50	5	be2276c9a1994579ba1d2998b49bf549c1324d44
ToppCell	Mild-T/NK_proliferative\|Mild / Disease group and Cell class	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	2.90e-06	199	50	5	64a5c91243ee999ea21ffddd450d3e5fdbf6470b
ToppCell	(1)_T_cells-(1)_T_cell_dividing\|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	2.90e-06	199	50	5	33afdd1b1b951b360ababf440bc556fd9e1c1db2
ToppCell	Non-neuronal-Dividing\|World / Primary Cells by Cluster	EEF1D BRCA2 HMGB2 SMC2 CDC25C	2.97e-06	200	50	5	50fa7b34a05f2c5ebbc7d113bd8e31326688a231
ToppCell	Brain_organoid-organoid_Velasco_nature-6_mon-Neuronal-Ventral_Precursors\|6_mon / Sample Type, Dataset, Time_group, and Cell type.	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	2.97e-06	200	50	5	c8ea0db79b1521f8c90d0d749280c354d3907c3a
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-FOXM1\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	2.97e-06	200	50	5	4cfe08878a6981bf7b3567f9e82192d8f060ddde
ToppCell	Control-Control-Lymphocyte-T/NK-T/NK_proliferative\|Control / Disease, condition lineage and cell class	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	2.97e-06	200	50	5	6cf63dd57f6bc0c42e7182322dd24ff9afbe9186
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Stem_cells-Neuroepithelial_cell\|2m / Sample Type, Dataset, Time_group, and Cell type.	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	2.97e-06	200	50	5	0d9b8d51a7630e70e60c76c763ff82df4c559152
ToppCell	Control_saline-Endothelial-Endothelial-FOXM1\|Control_saline / Treatment groups by lineage, cell group, cell type	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	2.97e-06	200	50	5	9bbc7b5561151f6ff65f40b3226271def732e5d9
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-5w-Stem_cells-Neuroepithelial_cell\|5w / Sample Type, Dataset, Time_group, and Cell type.	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	2.97e-06	200	50	5	c865efaaaecccbf9c833d6c1cbe85809a3ec306d
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-6_mon-Proliferating-Cycling_Progenitors_nGenesUnder4k\|6_mon / Sample Type, Dataset, Time_group, and Cell type.	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	2.97e-06	200	50	5	8223d2c9b9e05b1d26e3de1bc0226d175af2e7b2
ToppCell	control-T/NK_proliferative\|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	2.97e-06	200	50	5	1da366e35a05f73253629663eeea1fed4ebd7b52
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Stem_cells\|2m / Sample Type, Dataset, Time_group, and Cell type.	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	2.97e-06	200	50	5	0675f580ccef705875854247bbfd4ee2bcf126a1
ToppCell	Biopsy_Control_(H.)-Immune-Proliferating_Macrophages\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	2.97e-06	200	50	5	ce9fad55f779afd3d6c5a9c5a15e2d9f548b7c7e
ToppCell	(0)_NK_cells-(0)_NK_dividing\|(0)_NK_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	2.97e-06	200	50	5	1a630bb327070ffcb111ec36bd8fd4be3627ca2a
ToppCell	metastatic_Lymph_Node-T/NK_cells-Undetermined\|T/NK_cells / Location, Cell class and cell subclass	BRCA2 GAPDH ATAD5 HMGB2 SMC2	2.97e-06	200	50	5	9c2095dcf70f1288d55d0ff4a97efd4fd8d0c9ee
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Proliferating-cycling_ventral_progenitors\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	2.97e-06	200	50	5	9359faa749f41aaef70b4874f20b4eed2dc12cc2
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-5w-Stem_cells\|5w / Sample Type, Dataset, Time_group, and Cell type.	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	2.97e-06	200	50	5	2ee167b8bddd11fd5b1f61f87fcdf757aee3193e
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Proliferating\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	2.97e-06	200	50	5	cea58274efbe7f9e3c3ef9fbb768ebfb917e21d9
ToppCell	NS-critical-d_07-13-Lymphoid-NKT-proliferating\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	2.97e-06	200	50	5	7f5cd05bb1b9a83baceddb7d7f0a9ec9781cda29
ToppCell	Biopsy_Other_PF-Immune-Proliferating_Macrophages\|Biopsy_Other_PF / Sample group, Lineage and Cell type	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	2.97e-06	200	50	5	61473e8613f39a92002d5b631e6bd563735566e4
ToppCell	Non-neuronal-Dividing-Radial_Glia-vRG\|World / Primary Cells by Cluster	EEF1D BRCA2 HMGB2 SMC2 CDC25C	2.97e-06	200	50	5	7596143925cd403ec7baceef87d19d570e48586a
ToppCell	tumor_Lung-T/NK_cells-Undetermined\|T/NK_cells / Location, Cell class and cell subclass	GAPDH ATAD5 HMGB2 SMC2 CDC25C	2.97e-06	200	50	5	a1ef1b4824b2d56f6b2af15d698f58fc5590c392
ToppCell	Biopsy_IPF-Immune-Proliferating_Macrophages\|Biopsy_IPF / Sample group, Lineage and Cell type	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	2.97e-06	200	50	5	8abb2c25422717e994468ac02d8260344341467f
ToppCell	Non-neuronal-Dividing-Radial_Glia\|World / Primary Cells by Cluster	EEF1D BRCA2 HMGB2 SMC2 CDC25C	2.97e-06	200	50	5	ecbbad00e16041a9e1cd88d8bd7279a1b52c0aa4
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Stem_cells-Neuroepithelial_cell\|6m / Sample Type, Dataset, Time_group, and Cell type.	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	2.97e-06	200	50	5	55501f83409e0174c756a13ad8077f5b59975e27
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Stem_cells\|6m / Sample Type, Dataset, Time_group, and Cell type.	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	2.97e-06	200	50	5	b9aad527d3ad5bc701e93fa2afdebf695b2a74bb
ToppCell	Sepsis-Leuk-UTI-Lymphocyte-T/NK-T/NK_proliferative\|Leuk-UTI / Disease, condition lineage and cell class	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	2.97e-06	200	50	5	093e97395be23092229521cc55aaaee8befbc149
ToppCell	critical-Lymphoid-NKT-proliferating\|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	2.97e-06	200	50	5	d698458b90bf8256fe664618ef27620aa910b02a
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-6_mon-Proliferating\|6_mon / Sample Type, Dataset, Time_group, and Cell type.	BRCA2 ATAD5 HMGB2 SMC2 CDC25C	2.97e-06	200	50	5	8f9e76048ae6f45218a09a95a2c4b31e8a8937b2
ToppCell	PND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	BRCA2 ATAD5 HMGB2 SMC2	3.05e-05	159	50	4	e9c51e611ebd427bbe51e3e036c14122c36ea372
ToppCell	LPS-antiTNF-Endothelial-Endothelial-FOXM1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BRCA2 HMGB2 SMC2 CDC25C	3.36e-05	163	50	4	5285318c52aa31c9b22dc2ffff078e32e408604d
ToppCell	Dividing_Macrophages-Donor_08\|World / lung cells shred on cell class, cell subclass, sample id	BRCA2 HMGB2 SMC2 CDC25C	3.87e-05	169	50	4	eb0c993ef2eea73bc4881182520922ce9ae9368f
ToppCell	Dividing_Macrophages-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	BRCA2 HMGB2 SMC2 CDC25C	3.87e-05	169	50	4	bc859a103cad567caf50c3c3882d2d2017807c73
ToppCell	PND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ATAD5 HMGB2 SMC2 AIM2	4.05e-05	171	50	4	845f312f8cbe29d820da25f0e6d75deb382bbfd8
ToppCell	367C-Lymphocytic-NK_cells-Proliferating_NK_cell\|367C / Donor, Lineage, Cell class and subclass (all cells)	BRCA2 ATAD5 SMC2 CDC25C	4.05e-05	171	50	4	4ede6e916e593f208f2f8ccf82ef2335e061fc86
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	BRCA2 ATAD5 HMGB2 CDC25C	4.33e-05	174	50	4	84da9faff088d05233183b425385beb054c92d1b
ToppCell	3'-Distal_airway-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BRCA2 HMGB2 SMC2 CDC25C	4.33e-05	174	50	4	46cbb462173a684ceb9e680f9259dc3b133763f7
ToppCell	AT1-AT2_cells-HP_01\|World / lung cells shred on cell class, cell subclass, sample id	ANK2 MAP2 ETNPPL ABCA8	4.43e-05	175	50	4	9a95ab5c361ebaa8747983c5a0d69025682a19ad
ToppCell	367C-Lymphocytic-NK_cells-Proliferating_NK_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	BRCA2 ATAD5 SMC2 CDC25C	4.43e-05	175	50	4	0b1aaa028ba844d4bcb4509fdab8bee648373935
ToppCell	PND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HMGB2 ZNF683 SMC2 CDC25C	4.43e-05	175	50	4	ae7e0448ffd11b8908d0f6d99ff737faf5eca4bf
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_G2M\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HMGB2 MYO1B SMC2 CDC25C	4.43e-05	175	50	4	3e56695a9db97cb1d3503425c48eb79bbf99213e
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HMGB2 MYO1B SMC2 CDC25C	4.63e-05	177	50	4	2b63f0529ef73e0eede9b7ef1f08b0a0426a9c82
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-Alveolar_macrophage_proliferating_L.1.0.7.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BRCA2 HMGB2 SMC2 CDC25C	5.05e-05	181	50	4	73b1b59810f60e3e39ca1d5073a5a0d4f5377e6e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	BRCA2 HMGB2 SMC2 CDC25C	5.16e-05	182	50	4	336cd05e46a741185ce3c59ee67a4b07fa6a5101
ToppCell	368C-Epithelial_cells-Epithelial-F_(Ciliated)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	TMEM232 NEK5 LCA5L SPAG17	5.16e-05	182	50	4	975f6275777fc578eba528e50f69891c66ec44ad
ToppCell	368C-Epithelial_cells-Epithelial-F_(Ciliated)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	TMEM232 NEK5 LCA5L SPAG17	5.16e-05	182	50	4	f8c28fa76751062c4cfba0db8af1b377f947f739
ToppCell	TCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-5\|TCGA-Liver / Sample_Type by Project: Shred V9	BRCA2 ATAD5 HMGB2 SMC2	5.27e-05	183	50	4	f604a8b62c7088fad8365dbf8d910fc980bd3ba8
ToppCell	367C-Lymphocytic-NK_cells-Proliferating_NK_cell\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	BRCA2 ATAD5 SMC2 CDC25C	5.27e-05	183	50	4	a716b446c2bf5aa294b8f580aa845098fae76354
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NSD1 KMT2A REL NIPBL	5.38e-05	184	50	4	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	Dividing_Macrophages-IPF_01\|World / lung cells shred on cell class, cell subclass, sample id	BRCA2 ATAD5 SMC2 CDC25C	5.38e-05	184	50	4	f15ce786d25c6546804a6d1efcc2ad645f2ef54e
Computational	Neighborhood of ZNF198	CREBRF EPC2 TOMM70 KMT5B RABGAP1L	2.23e-05	117	32	5	GCM_ZNF198
Computational	Genes in the cancer module 198.	MAP2 CSTF3 KMT2A HMGB2 SMC2 CDC25C	2.33e-04	303	32	6	MODULE_198
Drug	AC1NRACZ	PPIL4 TRIM13 PPIB	2.30e-06	12	51	3	CID005287816
Drug	Harmol hydrochloride monohydrate [40580-83-4]; Down 200; 15.8uM; MCF7; HT_HG-U133A	DNAJC17 ATAD5 RABGAP1L CDC25C NIPBL BICD1	4.24e-06	191	51	6	6022_DN
Drug	GW5638	GAPDH PPIL4 PPIB	1.37e-05	21	51	3	CID005288494
Disease	Weaver syndrome	NSD1 KMT2A	2.92e-05	5	51	2	C0265210
Disease	Cornelia De Lange Syndrome	KMT2A NIPBL	8.15e-05	8	51	2	C0270972
Disease	Alzheimer's disease (implicated_via_orthology)	ANK2 MAP2 GAPDH	1.33e-04	57	51	3	DOID:10652 (implicated_via_orthology)
Disease	Colorectal Carcinoma	ANK2 MAP2 GAPDH MYO1B SPAG17 ABCA8 RASAL2	1.95e-04	702	51	7	C0009402
Disease	sleep duration	CNBD1 MAP2 KMT2A CDC25C FAM3D	4.00e-04	362	51	5	EFO_0005271
Disease	syndrome (implicated_via_orthology)	NSD1 SCAF4	4.40e-04	18	51	2	DOID:225 (implicated_via_orthology)
Disease	facial asymmetry measurement	CNBD1 CDC25C	4.92e-04	19	51	2	EFO_0009751
Disease	Neurodevelopmental Disorders	ANK2 KMT5B KMT2A	5.66e-04	93	51	3	C1535926
Disease	interleukin-8 measurement	EPC2 KMT2A	1.32e-03	31	51	2	EFO_0004811
Disease	endometrial cancer (is_implicated_in)	BRCA2 CDC25C	1.78e-03	36	51	2	DOID:1380 (is_implicated_in)
Disease	Malignant neoplasm of urinary bladder	BPTF BRCA2 KMT2A	1.88e-03	141	51	3	C0005684

Protein segments in the cluster

Peptide	Gene	Start	Entry
DNKIYPKNTKKKRVD	ATAD5	1436	Q96QE3
EASDVVRQKKKYPKK	EPC2	326	Q52LR7
KAEIKALKEKYNKSV	BICD1	431	Q96G01
CKDYVKKAKVKINPV	CREBRF	231	Q8IUR6
EKVDKQYKSVTKPKP	AIM2	86	O14862
YKVLQEQIKEKKAAK	C1orf131	211	Q8NDD1
KDNKPKIYLKGECLK	BPTF	1536	Q12830
QYAEKKAKKPALVAK	EEF1D	181	P29692
PYKFQKGKDVKKEFV	ETNPPL	151	Q8TBG4
RKEPKAKSDKYLKQQ	RBM20	761	Q5T481
VKKDKPEKELKAFCA	RBM27	36	Q9P2N5
EEYDQIFAPKKKQKK	NSD1	1286	Q96L73
LKDKVKPKQDTKYDL	PPIL4	351	Q8WUA2
KQKRDYKKEPKQEES	ANK2	2606	Q01484
KEIQVKKYKCGLIKP	FAM3D	46	Q96BQ1
KKKRKPKVDYQQVFT	LSM11	326	P83369
QKAAKLKEKYEKDIA	HMGB2	146	P26583
ALKEKVIKAVVPAKY	MAT2A	221	P31153
KVVLYKNLPIKKDKE	KMT5B	481	Q4FZB7
SKNPEQKYKAKKGVK	NEK5	566	Q6P3R8
AEYVPEKVKKAEKKL	CSTF3	11	Q12996
EKVKKAEKKLEENPY	CSTF3	16	Q12996
QDKDKPLKKRKQDSY	NIPBL	496	Q6KC79
EKKKKKDKNNYVGLV	RASAL2	236	Q9UJF2
KQPVVKEKEKKKYNV	LCA5L	86	O95447
KFKDNTIPDKVKKKY	CDC25C	231	P30307
ACNIKVPTKKLKKYE	RABGAP1L	776	Q5R372
DETSYKGKKIPKDQK	BRCA2	596	P51587
EVLNPRKKCKKKKYV	CPNE9	256	Q8IYJ1
KAADKEVKKAYRQKA	DNAJC17	21	Q9NVM6
PSKAYLQKQAKAVKK	KMT2A	1201	Q03164
IVEKFIKKCKPEYKV	SCAF4	46	O95104
QKILEYEEQKKQKKP	DENND2D	451	Q9H6A0
YEEQKKQKKPREKTV	DENND2D	456	Q9H6A0
KDVKAAVKYLLNKKP	OR13C3	331	Q8NGS6
AKKLVNPKYALVKAK	FAM83G	341	A6ND36
KKGEYVFPAKKKLQE	MOV10	601	Q9HCE1
KPAKYDDIKKVVKQA	GAPDH	251	P04406
KQPGEKKAAKLKEKY	HMGB1P1	141	B2RPK0
KKKGPKVTVKVYFDL	PPIB	36	P23284
AKCVNYDEKNLKIKP	SHPRH	686	Q149N8
KSPYKEKSKEEQVKI	SPAG17	986	Q6Q759
TKEYKGKPDKIEALK	ABCA8	486	O94911
LKIPAKGYAKIKEEK	CNBD1	291	Q8NA66
KGIVEKYNKIKISPK	TRIM13	76	O60858
DQTKYPNKKLESVKK	TMEM232	546	C9JQI7
GKEKAKEKYKNREPL	TOMM70	236	O94826
PDEKDTYGNKAKKQK	REL	281	Q04864
YKKIAAQKTIEKKEA	SMC2	176	O95347
KKAVYKKAELAKKTE	MAP2	1461	P11137
KELPEKKKMKYIQDF	UBTF	151	P17480
KKFTVKYPQNKDKLG	ZNF683	121	Q8IZ20
ENNILAKKKPYKCDK	ZFP90	201	Q8TF47
NKNPKYKKLKDAIEE	MYO1B	971	O43795