Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	actin filament binding	LIMA1 NRAP MYO5B MYO9A SPTAN1 MYO1B MYO18B	8.90e-06	227	65	7	GO:0051015
GeneOntologyMolecularFunction	cytoskeletal protein binding	CEP350 LIMA1 DST NRAP MYO5B CENPF MYO9A SPTAN1 EML6 MYO1B MYO18B DNM1 CFAP157	4.48e-05	1099	65	13	GO:0008092
GeneOntologyMolecularFunction	actin binding	LIMA1 DST NRAP MYO5B MYO9A SPTAN1 MYO1B MYO18B	1.57e-04	479	65	8	GO:0003779
GeneOntologyMolecularFunction	microfilament motor activity	MYO5B MYO9A MYO1B	2.56e-04	38	65	3	GO:0000146
GeneOntologyMolecularFunction	intracellularly cAMP-activated cation channel activity	HCN4 HCN1	4.62e-04	10	65	2	GO:0005222
GeneOntologyMolecularFunction	microtubule binding	CEP350 DST CENPF EML6 DNM1 CFAP157	4.93e-04	308	65	6	GO:0008017
GeneOntologyMolecularFunction	phosphatidylinositol-3,4,5-trisphosphate binding	HCN1 MYO1B DNM1	5.45e-04	49	65	3	GO:0005547
GeneOntologyMolecularFunction	cytoskeletal motor activity	MYO5B MYO9A MYO1B MYO18B	5.94e-04	118	65	4	GO:0003774
GeneOntologyMolecularFunction	sodium channel activity	HCN4 HCN1 SCNN1D	6.49e-04	52	65	3	GO:0005272
GeneOntologyMolecularFunction	phosphatidylinositol bisphosphate binding	HCN1 PLEKHA5 MYO1B DNM1	6.53e-04	121	65	4	GO:1902936
GeneOntologyMolecularFunction	nuclear estrogen receptor binding	ZNF366 PIK3R1 TACC1	6.87e-04	53	65	3	GO:0030331
GeneOntologyMolecularFunction	intracellularly cyclic nucleotide-activated monoatomic cation channel activity	HCN4 HCN1	7.95e-04	13	65	2	GO:0005221
GeneOntologyMolecularFunction	cyclic nucleotide-activated monoatomic ion channel activity	HCN4 HCN1	7.95e-04	13	65	2	GO:0043855
GeneOntologyMolecularFunction	tubulin binding	CEP350 DST CENPF EML6 DNM1 CFAP157	2.66e-03	428	65	6	GO:0015631
GeneOntologyMolecularFunction	cAMP binding	HCN4 HCN1	2.98e-03	25	65	2	GO:0030552
GeneOntologyMolecularFunction	voltage-gated sodium channel activity	HCN4 HCN1	3.22e-03	26	65	2	GO:0005248
GeneOntologyMolecularFunction	K63-linked polyubiquitin modification-dependent protein binding	ASCC2 MINDY2	3.22e-03	26	65	2	GO:0070530
GeneOntologyMolecularFunction	nuclear receptor binding	ZNF366 PIK3R1 TMF1 TACC1	3.23e-03	187	65	4	GO:0016922
GeneOntologyMolecularFunction	phosphatidylinositol binding	HCN1 PLEKHA5 MYO1B WDFY3 DNM1	3.66e-03	316	65	5	GO:0035091
GeneOntologyMolecularFunction	phosphatidylinositol-4,5-bisphosphate binding	HCN1 MYO1B DNM1	3.68e-03	95	65	3	GO:0005546
GeneOntologyMolecularFunction	phosphatidylinositol phosphate binding	HCN1 PLEKHA5 MYO1B DNM1	4.03e-03	199	65	4	GO:1901981
GeneOntologyCellularComponent	myosin complex	MYO5B MYO9A MYO1B MYO18B	3.62e-05	59	66	4	GO:0016459
GeneOntologyCellularComponent	HCN channel complex	HCN4 HCN1	5.87e-05	4	66	2	GO:0098855
GeneOntologyCellularComponent	actin cytoskeleton	LIMA1 DST MYO5B MYO9A SPTAN1 SCNN1D ANKRD26 MYO1B MYO18B	7.86e-05	576	66	9	GO:0015629
GeneOntologyCellularComponent	cell cortex region	MYO5B TCHP RIMS1	3.88e-04	45	66	3	GO:0099738
GeneOntologyCellularComponent	ciliary transition fiber	TCHP CENPF	4.35e-04	10	66	2	GO:0097539
GeneOntologyCellularComponent	apical cortex	MYO5B TCHP	4.35e-04	10	66	2	GO:0045179
GeneOntologyCellularComponent	unconventional myosin complex	MYO9A MYO18B	5.30e-04	11	66	2	GO:0016461
GeneOntologyCellularComponent	microtubule organizing center	CEP350 FAM184A TCHP CENPF KIAA1217 ANKRD26 TACC1 ZNF365 TTC19 CFAP157	5.79e-04	919	66	10	GO:0005815
GeneOntologyCellularComponent	centrosome	CEP350 FAM184A TCHP CENPF KIAA1217 ANKRD26 TACC1 ZNF365 TTC19	6.73e-04	770	66	9	GO:0005813
GeneOntologyCellularComponent	fascia adherens	NRAP SPTAN1	7.49e-04	13	66	2	GO:0005916
GeneOntologyCellularComponent	intercalated disc	DST NRAP SPTAN1	1.30e-03	68	66	3	GO:0014704
GeneOntologyCellularComponent	Z disc	DST NRAP SPTAN1 MYO18B	1.33e-03	151	66	4	GO:0030018
GeneOntologyCellularComponent	I band	DST NRAP SPTAN1 MYO18B	1.88e-03	166	66	4	GO:0031674
GeneOntologyCellularComponent	presynaptic active zone membrane	CELSR3 HCN1 RIMS1	1.93e-03	78	66	3	GO:0048787
Domain	Myosin_head_motor_dom	MYO5B MYO9A MYO1B MYO18B	7.96e-06	38	63	4	IPR001609
Domain	MYOSIN_MOTOR	MYO5B MYO9A MYO1B MYO18B	7.96e-06	38	63	4	PS51456
Domain	Myosin_head	MYO5B MYO9A MYO1B MYO18B	7.96e-06	38	63	4	PF00063
Domain	MYSc	MYO5B MYO9A MYO1B MYO18B	7.96e-06	38	63	4	SM00242
Domain	Ion_trans_N	HCN4 HCN1	6.69e-05	4	63	2	PF08412
Domain	TEX28/TMCC	TMCC2 TMCC1	6.69e-05	4	63	2	IPR019394
Domain	Ion_trans_N	HCN4 HCN1	6.69e-05	4	63	2	IPR013621
Domain	Tmemb_cc2	TMCC2 TMCC1	6.69e-05	4	63	2	PF10267
Domain	IQ	MYO5B MYO9A MYO1B MYO18B	9.64e-05	71	63	4	PF00612
Domain	IQ	MYO5B MYO9A MYO1B MYO18B	1.61e-04	81	63	4	SM00015
Domain	IQ_motif_EF-hand-BS	MYO5B MYO9A MYO1B MYO18B	2.42e-04	90	63	4	IPR000048
Domain	IQ	MYO5B MYO9A MYO1B MYO18B	2.74e-04	93	63	4	PS50096
Domain	K_chnl_volt-dep_EAG/ELK/ERG	HCN4 HCN1	9.93e-04	14	63	2	IPR003938
Domain	cNMP-bd_CS	HCN4 HCN1	1.30e-03	16	63	2	IPR018488
Domain	Spectrin	DST SPTAN1	2.71e-03	23	63	2	PF00435
Domain	Spectrin_repeat	DST SPTAN1	4.29e-03	29	63	2	IPR002017
Domain	EGF_LAM_2	CELSR3 LAMB1	4.58e-03	30	63	2	PS50027
Domain	EGF_LAM_1	CELSR3 LAMB1	4.58e-03	30	63	2	PS01248
Domain	CNMP_BINDING_1	HCN4 HCN1	5.20e-03	32	63	2	PS00888
Domain	CNMP_BINDING_2	HCN4 HCN1	5.20e-03	32	63	2	PS00889
Domain	Spectrin/alpha-actinin	DST SPTAN1	5.20e-03	32	63	2	IPR018159
Domain	SPEC	DST SPTAN1	5.20e-03	32	63	2	SM00150
Domain	cNMP	HCN4 HCN1	5.86e-03	34	63	2	SM00100
Domain	Znf_FYVE-rel	RIMS1 WDFY3	5.86e-03	34	63	2	IPR017455
Domain	cNMP_binding	HCN4 HCN1	5.86e-03	34	63	2	PF00027
Domain	cNMP-bd_dom	HCN4 HCN1	6.20e-03	35	63	2	IPR000595
Domain	CNMP_BINDING_3	HCN4 HCN1	6.20e-03	35	63	2	PS50042
Domain	Laminin_EGF	CELSR3 LAMB1	6.20e-03	35	63	2	PF00053
Domain	EGF_Lam	CELSR3 LAMB1	6.20e-03	35	63	2	SM00180
Domain	SH3_domain	DST PIK3R1 SPTAN1 FYB2	6.49e-03	220	63	4	IPR001452
Domain	Znf_FYVE	RIMS1 WDFY3	7.28e-03	38	63	2	IPR000306
Domain	cNMP-bd-like	HCN4 HCN1	7.28e-03	38	63	2	IPR018490
Domain	Laminin_EGF	CELSR3 LAMB1	7.28e-03	38	63	2	IPR002049
Domain	ZF_FYVE	RIMS1 WDFY3	8.04e-03	40	63	2	PS50178
Pathway	REACTOME_RHOV_GTPASE_CYCLE	DST MYO9A PIK3R1 SPTAN1	4.61e-06	37	43	4	M41819
Pathway	REACTOME_RHOV_GTPASE_CYCLE	DST MYO9A PIK3R1 SPTAN1	4.61e-06	37	43	4	MM15610
Pathway	REACTOME_RHOU_GTPASE_CYCLE	DST PIK3R1 SPTAN1	2.24e-04	39	43	3	MM15607
Pathway	REACTOME_RHOU_GTPASE_CYCLE	DST PIK3R1 SPTAN1	2.41e-04	40	43	3	M41816
Pathway	REACTOME_RND3_GTPASE_CYCLE	DST PIK3R1 ANKRD26	2.79e-04	42	43	3	M41826
Pathway	REACTOME_RND1_GTPASE_CYCLE	DST PIK3R1 ANKRD26	2.79e-04	42	43	3	M41828
Pathway	REACTOME_RND3_GTPASE_CYCLE	DST PIK3R1 ANKRD26	2.79e-04	42	43	3	MM15677
Pathway	REACTOME_RND2_GTPASE_CYCLE	DST PIK3R1 ANKRD26	3.00e-04	43	43	3	M41827
Pathway	REACTOME_RND1_GTPASE_CYCLE	DST PIK3R1 ANKRD26	3.00e-04	43	43	3	MM15679
Pathway	REACTOME_RND2_GTPASE_CYCLE	DST PIK3R1 ANKRD26	3.21e-04	44	43	3	MM15678
Pathway	REACTOME_RHO_GTPASE_CYCLE	DST MYO9A PIK3R1 SPTAN1 DOCK7 ANKRD26 FAM91A1	3.30e-04	439	43	7	MM15595
Pathway	REACTOME_RHO_GTPASE_CYCLE	DST MYO9A PIK3R1 SPTAN1 DOCK7 ANKRD26 FAM91A1	3.84e-04	450	43	7	M27078
Pathway	REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3	DST CENPF MYO9A PIK3R1 SPTAN1 DOCK7 ANKRD26 FAM91A1	6.71e-04	649	43	8	MM15690
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	LIMA1 PTPN9 DST HCN4 CENPF HCN1 KIAA1217 SPTAN1 DOCK7 TMED9 PLEKHA5 RIMS1 WDFY3 DNM1	2.88e-09	963	66	14	28671696
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	CEP350 LIMA1 DST MYO9A KIAA1217 SPTAN1 DOCK7 ANKRD26 PLEKHA5 BECN1 TMCC1	6.24e-07	861	66	11	36931259
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	CEP350 CHCHD3 GDAP1L1 DST CELSR3 PIK3R1 HCN1 SPTAN1 LAMB1 WDFY3 DNM1 BECN1 ZNF365	7.44e-07	1285	66	13	35914814
Pubmed	Protein partners of dynamin-1 in the retina.	LIMA1 SPTAN1 DNM1	7.76e-07	10	66	3	23746204
Pubmed	Intersectin (ITSN) family of scaffolds function as molecular hubs in protein interaction networks.	DST PIK3R1 TMF1 TACC1 BECN1	2.31e-06	111	66	5	22558309
Pubmed	Identification and overlapping expression of multiple unconventional myosin genes in vertebrate cell types.	MYO5B MYO9A MYO1B	2.34e-06	14	66	3	8022818
Pubmed	Inhibition of the PI3K/AKT Signaling Pathway or Overexpression of Beclin1 Blocks Reinfection of Streptococcus pneumoniae After Infection of Influenza A Virus in Severe Community-Acquired Pneumonia.	PIK3R1 BECN1	3.55e-06	2	66	2	31267272
Pubmed	Dynamin inhibits phosphatidylinositol 3-kinase in hematopoietic cells.	PIK3R1 DNM1	3.55e-06	2	66	2	11341978
Pubmed	Molecular composition and functional properties of f-channels in murine embryonic stem cell-derived pacemaker cells.	HCN4 HCN1	3.55e-06	2	66	2	19135060
Pubmed	Peripheral N- and C-terminal domains determine deactivation kinetics of HCN channels.	HCN4 HCN1	3.55e-06	2	66	2	17548059
Pubmed	Colocalization of hyperpolarization-activated, cyclic nucleotide-gated channel subunits in rat retinal ganglion cells.	HCN4 HCN1	3.55e-06	2	66	2	21456027
Pubmed	Hyperpolarization-activated channels HCN1 and HCN4 mediate responses to sour stimuli.	HCN4 HCN1	3.55e-06	2	66	2	11675786
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	DST TMCC2 PLEKHA5 WDFY3 SMC5 WDR48	4.51e-06	225	66	6	12168954
Pubmed	Analysis of interaction partners for eukaryotic translation elongation factor 1A M-domain by functional proteomics.	DST TTC14 ANKRD26	7.27e-06	20	66	3	21689717
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	CEP350 SPTAN1 DOCK7 ANKRD26 ASCC2 TAF2 SMC5 PHF10 WDR48	8.97e-06	724	66	9	36232890
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	CHCHD3 HCN4 HCN1 KIAA1217 SPTAN1 TMCC2 DOCK7 FAM91A1 TACC1 RIMS1 TMCC1	9.14e-06	1139	66	11	36417873
Pubmed	The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.	LIMA1 CENPF SPTAN1 FAM91A1 PLEKHA5 WDR48	9.42e-06	256	66	6	33397691
Pubmed	EP3 activation facilitates bladder excitability via HCN channels on ICCs.	HCN4 HCN1	1.06e-05	3	66	2	28131828
Pubmed	A LIMA1 variant promotes low plasma LDL cholesterol and decreases intestinal cholesterol absorption.	LIMA1 MYO5B	1.06e-05	3	66	2	29880681
Pubmed	HCN channels in the mammalian cochlea: Expression pattern, subcellular location, and age-dependent changes.	HCN4 HCN1	1.06e-05	3	66	2	33181864
Pubmed	Ventricular HCN channels decrease the repolarization reserve in the hypertrophic heart.	HCN4 HCN1	1.06e-05	3	66	2	22652004
Pubmed	Cytoplasmic cAMP-sensing domain of hyperpolarization-activated cation (HCN) channels uses two structurally distinct mechanisms to regulate voltage gating.	HCN4 HCN1	1.06e-05	3	66	2	21187420
Pubmed	Novel insights into the distribution of cardiac HCN channels: an expression study in the mouse heart.	HCN4 HCN1	1.06e-05	3	66	2	21945247
Pubmed	Tetramerization dynamics of C-terminal domain underlies isoform-specific cAMP gating in hyperpolarization-activated cyclic nucleotide-gated channels.	HCN4 HCN1	1.06e-05	3	66	2	22006928
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	CHCHD3 FAM184A ABCB7 TCHP PIK3R1 SPTAN1 ANKRD26 ASCC2 LAMB1 PLEKHA5 TACC1 TMCC1	2.06e-05	1487	66	12	33957083
Pubmed	Functional expression of the human HCN3 channel.	HCN4 HCN1	2.12e-05	4	66	2	16043489
Pubmed	Investigation of hyperpolarization-activated cyclic nucleotide-gated channels in interstitial cells of Cajal of human bladder.	HCN4 HCN1	2.12e-05	4	66	2	22748890
Pubmed	Identification of a gene encoding a hyperpolarization-activated pacemaker channel of brain.	HCN4 HCN1	2.12e-05	4	66	2	9630217
Pubmed	Interactive cloning with the SH3 domain of N-src identifies a new brain specific ion channel protein, with homology to eag and cyclic nucleotide-gated channels.	HCN4 HCN1	2.12e-05	4	66	2	9405696
Pubmed	Role of subunit heteromerization and N-linked glycosylation in the formation of functional hyperpolarization-activated cyclic nucleotide-gated channels.	HCN4 HCN1	2.12e-05	4	66	2	12928435
Pubmed	Genetic analysis of hyperpolarization-activated cyclic nucleotide-gated cation channels in sudden unexpected death in epilepsy cases.	HCN4 HCN1	2.12e-05	4	66	2	21615589
Pubmed	Hyperpolarization-activated and cyclic nucleotide-gated channels are differentially expressed in juxtaglomerular cells in the olfactory bulb of mice.	HCN4 HCN1	2.12e-05	4	66	2	20140458
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	LIMA1 DST TCHP SPTAN1 DOCK7 ANKRD26 PLEKHA5	2.21e-05	446	66	7	24255178
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	CHCHD3 LIMA1 DST MYO5B CENPF KIAA1217 SPTAN1 DOCK7 ASCC2 PLEKHA5 MYO1B	2.28e-05	1257	66	11	36526897
Pubmed	Faciogenital Dysplasia 5 supports cancer stem cell traits in basal-like breast cancer by enhancing EGFR stability.	LIMA1 DST SPTAN1 DOCK7 MYO1B	3.23e-05	191	66	5	33762435
Pubmed	Developmental HCN channelopathy results in decreased neural progenitor proliferation and microcephaly in mice.	HCN4 HCN1	3.53e-05	5	66	2	34429357
Pubmed	Thalamocortical control of cell-type specificity drives circuits for processing whisker-related information in mouse barrel cortex.	CELSR3 RIMS1	3.53e-05	5	66	2	37770450
Pubmed	Regulation of HCN channel surface expression by a novel C-terminal protein-protein interaction.	HCN4 HCN1	3.53e-05	5	66	2	15564593
Pubmed	CFAP157 is a murine downstream effector of FOXJ1 that is specifically required for flagellum morphogenesis and sperm motility.	CEP350 CFAP157	3.53e-05	5	66	2	27965440
Pubmed	Huntingtin interacting proteins are genetic modifiers of neurodegeneration.	CHCHD3 PIK3R1 SPTAN1 TACC1 DNM1	3.74e-05	197	66	5	17500595
Pubmed	The P-body component USP52/PAN2 is a novel regulator of HIF1A mRNA stability.	CHCHD3 LIMA1 MYO5B SPTAN1 DOCK7 MYO1B	3.79e-05	328	66	6	23398456
Pubmed	A human MAP kinase interactome.	CEP350 DST MYO9A PIK3R1 SPTAN1 LAMB1 PLEKHA5	3.81e-05	486	66	7	20936779
Pubmed	Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.	CELSR3 HCN4 PIK3R1 RIMS1 MYO18B DNM1	3.86e-05	329	66	6	17474147
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	CEP350 DST MYO9A DOCK7 PLEKHA5	4.96e-05	209	66	5	36779422
Pubmed	USP1 (ubiquitin specific peptidase 1) targets ULK1 and regulates its cellular compartmentalization and autophagy.	BECN1 WDR48	5.29e-05	6	66	2	30335599
Pubmed	Differential expression of hyperpolarization-activated cyclic nucleotide-gated channel subunits during hippocampal development in the mouse.	HCN4 HCN1	5.29e-05	6	66	2	25761792
Pubmed	PtdIns(3)P controls cytokinesis through KIF13A-mediated recruitment of FYVE-CENT to the midbody.	BECN1 TTC19	5.29e-05	6	66	2	20208530
Pubmed	New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.	LIMA1 ABCB7 DST CELSR3 KIAA1217 SPTAN1 MINDY2	5.36e-05	513	66	7	25798074
Pubmed	Ptbp2 represses adult-specific splicing to regulate the generation of neuronal precursors in the embryonic brain.	CEP350 DEPDC5 DNM1	5.68e-05	39	66	3	22802532
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	LIMA1 DST KIAA1217 SPTAN1 PLEKHA5 SMC5	6.35e-05	360	66	6	33111431
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	LIMA1 DST MYO5B MYO9A KIAA1217 SPTAN1 DOCK7 TMED9 PLEKHA5 RIMS1 DNM1	7.38e-05	1431	66	11	37142655
Pubmed	Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex.	PIK3R1 BECN1	7.40e-05	7	66	2	19270693
Pubmed	Transcription profiling of HCN-channel isotypes throughout mouse cardiac development.	HCN4 HCN1	7.40e-05	7	66	2	19421833
Pubmed	A comprehensive proteomics-based interaction screen that links DYRK1A to RNF169 and to the DNA damage response.	CENPF KIAA1217 SPTAN1 DOCK7	7.71e-05	118	66	4	30979931
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	CHCHD3 LIMA1 DST MYO5B CENPF SPTAN1 EML6 ANKRD26 MYO1B RIMS1 MINDY2	7.90e-05	1442	66	11	35575683
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	NLRP11 LIMA1 DST MYO1B TEX15	8.45e-05	234	66	5	36243803
Pubmed	A new role for the architecture of microvillar actin bundles in apical retention of membrane proteins.	LIMA1 MYO5B MYO1B	8.75e-05	45	66	3	22114352
Pubmed	Using brain cell-type-specific protein interactomes to interpret neurodevelopmental genetic signals in schizophrenia.	HCN4 HCN1 RIMS1	9.35e-05	46	66	3	37207277
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	LIMA1 DST KIAA1217 SPTAN1 FAM91A1 PLEKHA5 MYO1B	9.78e-05	565	66	7	25468996
Pubmed	Epidermolysis Bullosa Simplex	DST TGM5	9.86e-05	8	66	2	20301543
Pubmed	Transmembrane and coiled-coil domain family 1 is a novel protein of the endoplasmic reticulum.	TMCC2 TMCC1	9.86e-05	8	66	2	24454821
Pubmed	Regulation of membrane traffic by phosphoinositide 3-kinases.	PIK3R1 BECN1	9.86e-05	8	66	2	16467569
Pubmed	Mapping of unconventional myosins in mouse and human.	MYO5B MYO9A MYO1B	1.06e-04	48	66	3	8884266
Pubmed	Mechanisms and Consequences of Dopamine Depletion-Induced Attenuation of the Spinophilin/Neurofilament Medium Interaction.	KIAA1217 SPTAN1 MYO1B DNM1	1.16e-04	131	66	4	28634551
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DOCK7 FAM91A1 SMC5 DENND11 ZNF365 WDR48	1.24e-04	407	66	6	12693553
Pubmed	The unique N-terminal domain of the cAMP phosphodiesterase PDE4D4 allows for interaction with specific SH3 domains.	PIK3R1 SPTAN1	1.27e-04	9	66	2	10571082
Pubmed	The cell proliferation antigen Ki-67 organises heterochromatin.	LIMA1 DST CENPF DOCK7 PHF10 WDR48	1.29e-04	410	66	6	26949251
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	CEP350 CHCHD3 LIMA1 DST MYO5B CENPF DOCK7 TMED9 MYO1B	1.32e-04	1024	66	9	24711643
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	DST CENPF DOCK7 TMF1 PLEKHA5 HMG20B	1.44e-04	418	66	6	34709266
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	DST PIK3R1 KIAA1217 ANKRD26 PLEKHA5 WDR48	1.49e-04	421	66	6	36976175
Pubmed	A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.	CEP350 MYO5B TMF1 LAMB1 PLEKHA5 BECN1 TTC19	1.54e-04	608	66	7	16713569
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	CEP350 PTPN9 MYO5B PIK3R1 SPTAN1 TMF1 FAM91A1 MYO1B WDR48	1.58e-04	1049	66	9	27880917
Pubmed	International Union of Pharmacology. LI. Nomenclature and structure-function relationships of cyclic nucleotide-regulated channels.	HCN4 HCN1	1.58e-04	10	66	2	16382102
Pubmed	Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.	LIMA1 MYO5B SPTAN1 MYO1B WDR48	1.71e-04	272	66	5	31010829
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	CHCHD3 LIMA1 MYO5B TCHP PIK3R1 DOCK7 EIF3K PLEKHA5 FYB2 WDR48	1.84e-04	1321	66	10	27173435
Pubmed	Specificity of the binding of synapsin I to Src homology 3 domains.	PIK3R1 DNM1	1.93e-04	11	66	2	10899172
Pubmed	Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.	DST CENPF SPTAN1 ZNF365	2.00e-04	151	66	4	17043677
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	CEP350 CHCHD3 PTPN9 APOL3 TMED9 TAF2 WDFY3	2.06e-04	638	66	7	31182584
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	CEP350 DST TCHP SPTAN1 DOCK7 ANKRD26 FAM91A1	2.21e-04	645	66	7	25281560
Pubmed	RNF38 suppress growth and metastasis via ubiquitination of ACTN4 in nasopharyngeal carcinoma.	LIMA1 SPTAN1 MYO1B	2.28e-04	62	66	3	35568845
Pubmed	De novo genic mutations among a Chinese autism spectrum disorder cohort.	RIMS1 WDFY3	2.31e-04	12	66	2	27824329
Pubmed	Arrhythmia induced by spatiotemporal overexpression of calreticulin in the heart.	HCN4 HCN1	2.31e-04	12	66	2	17482496
Pubmed	DDX39B facilitates the malignant progression of hepatocellular carcinoma via activation of SREBP1-mediated de novo lipid synthesis.	LIMA1 SPTAN1 MYO1B	2.39e-04	63	66	3	37052853
Pubmed	Proximity interactions of the ubiquitin ligase Mind bomb 1 reveal a role in regulation of epithelial polarity complex proteins.	TCHP ANKRD26 ASCC2 PLEKHA5	3.07e-04	169	66	4	31462741
Pubmed	Pacsin 2 is required for the maintenance of a normal cardiac function in the developing mouse heart.	HCN4 HCN1	3.18e-04	14	66	2	29107716
Pubmed	Poly(ADP-ribosyl)ation of BRD7 by PARP1 confers resistance to DNA-damaging chemotherapeutic agents.	LIMA1 MYO9A PIK3R1 ASCC2 FAM91A1 PHF10	3.23e-04	486	66	6	30940648
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CEP350 MYO5B TMCC2 TTC14 ANKRD26 TMCC1	3.48e-04	493	66	6	15368895
Pubmed	Cytoplasmic dynein-1 cargo diversity is mediated by the combinatorial assembly of FTS-Hook-FHIP complexes.	MYO5B TMF1 FAM91A1	3.54e-04	72	66	3	34882091
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	CENPF ASCC2 PLEKHA5 SMC5 TGM5 TTC19	3.64e-04	497	66	6	36774506
Pubmed	Nuclear EGFR renders cells radio-resistant by binding mRNA species and triggering a metabolic switch to increase lactate production.	MYO9A SPTAN1	3.67e-04	15	66	2	26320552
Pubmed	Hyperpolarization-activated cyclic nucleotide-gated channels in olfactory sensory neurons regulate axon extension and glomerular formation.	HCN4 HCN1	3.67e-04	15	66	2	21147989
Pubmed	Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.	LIMA1 DST CENPF SPTAN1 DOCK7 MYO1B	4.00e-04	506	66	6	30890647
Pubmed	Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain.	MYO5B DENND11 MINDY2	4.16e-04	76	66	3	10574461
Pubmed	Rab40-Cullin5 complex regulates EPLIN and actin cytoskeleton dynamics during cell migration.	LIMA1 DST	4.18e-04	16	66	2	33999101
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	DST CENPF SPTAN1 EML6 TACC1	4.27e-04	332	66	5	37433992
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	FAM184A DST ASCC2 TMF1 EIF3K FAM91A1 TMED9 TAF2 TMCC1 HMG20B	4.96e-04	1497	66	10	31527615
Pubmed	Misexpression of Tbx18 in cardiac chambers of fetal mice interferes with chamber-specific developmental programs but does not induce a pacemaker-like gene signature.	HCN4 HCN1	5.32e-04	18	66	2	27180262
Pubmed	The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.	DST CENPF SPTAN1 TAF2	5.47e-04	197	66	4	20811636
Pubmed	Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.	CEP350 ABCB7 MYO5B CENPF ASCC2 EIF3K PLEKHA5	5.62e-04	754	66	7	33060197
Pubmed	Proteomic analysis of NMDA receptor-adhesion protein signaling complexes.	PIK3R1 SPTAN1 DNM1	5.97e-04	86	66	3	10862698
Interaction	TNIK interactions	DST CENPF HCN1 KIAA1217 SPTAN1 DOCK7 PLEKHA5 RIMS1 DNM1	4.02e-06	381	66	9	int:TNIK
Interaction	PFN1 interactions	CEP350 MYO9A PIK3R1 KIAA1217 SPTAN1 DOCK7 ANKRD26 TMF1 PLEKHA5 DNM1	5.74e-06	509	66	10	int:PFN1
Interaction	EBAG9 interactions	DST PIK3R1 SPTAN1 ANKRD26 TMF1 FAM91A1 PLEKHA5 TACC1	6.42e-06	303	66	8	int:EBAG9
Interaction	EPB41L4A interactions	DST KIAA1217 SPTAN1 ANKRD26 PLEKHA5 MYO1B	6.51e-06	140	66	6	int:EPB41L4A
Interaction	TBCK interactions	CHCHD3 LIMA1 MYO5B SPTAN1 MYO1B	7.25e-06	82	66	5	int:TBCK
Interaction	RAC2 interactions	CHCHD3 ABCB7 DST PIK3R1 SPTAN1 TMF1 FAM91A1 PLEKHA5 MYO1B TACC1 MYO18B	1.09e-05	674	66	11	int:RAC2
Interaction	AFDN interactions	LIMA1 DST TCHP KIAA1217 ANKRD26 TMF1 PLEKHA5 SMC5	1.28e-05	333	66	8	int:AFDN
Interaction	RHOV interactions	DST MYO9A PIK3R1 SPTAN1 ANKRD26 PLEKHA5 MYO1B	1.44e-05	243	66	7	int:RHOV
Interaction	STX6 interactions	PTPN9 DST SPTAN1 ANKRD26 TMF1 FAM91A1 PLEKHA5 MYO1B TACC1	1.47e-05	448	66	9	int:STX6
Interaction	RHOD interactions	CHCHD3 PIK3R1 SPTAN1 DOCK7 ANKRD26 FAM91A1 PLEKHA5 MYO1B TACC1 TTC19	1.58e-05	572	66	10	int:RHOD
Interaction	FER interactions	LIMA1 PIK3R1 TMF1 DNM1	2.16e-05	50	66	4	int:FER
Interaction	PEX5L interactions	HCN4 HCN1 KIAA1217 SPTAN1	2.93e-05	54	66	4	int:PEX5L
Interaction	GOLGA1 interactions	CEP350 DST TCHP ANKRD26 TMF1 FAM91A1	2.99e-05	183	66	6	int:GOLGA1
Interaction	MAPRE1 interactions	CEP350 LIMA1 DST KIAA1217 SPTAN1 ANKRD26 PLEKHA5 TACC1 TMCC1	4.33e-05	514	66	9	int:MAPRE1
Interaction	DAPK1 interactions	LIMA1 MYO5B SPTAN1 DOCK7 MYO1B BECN1	6.27e-05	209	66	6	int:DAPK1
Interaction	C11orf52 interactions	DST PIK3R1 SPTAN1 DOCK7 ANKRD26 PLEKHA5 MYO1B	6.96e-05	311	66	7	int:C11orf52
Interaction	DYRK1A interactions	CENPF KIAA1217 SPTAN1 DOCK7 LAMB1 PLEKHA5 DNM1 DENND11 ZNF365	7.50e-05	552	66	9	int:DYRK1A
Interaction	RND2 interactions	CHCHD3 DST PIK3R1 SPTAN1 ANKRD26 FAM91A1 PLEKHA5 TACC1	9.19e-05	440	66	8	int:RND2
Interaction	CDCA5 interactions	LIMA1 MYO5B CENPF SPTAN1 SMC5	9.58e-05	140	66	5	int:CDCA5
Interaction	ZFPL1 interactions	DST SPTAN1 ANKRD26 TMF1 FAM91A1 PLEKHA5 MYO1B TACC1	1.04e-04	448	66	8	int:ZFPL1
Interaction	MAPRE3 interactions	CEP350 DST CENPF KIAA1217 PLEKHA5 TACC1	1.06e-04	230	66	6	int:MAPRE3
Interaction	PHLPP1 interactions	LIMA1 CENPF KIAA1217 SPTAN1 FAM91A1 PLEKHA5 WDR48	1.07e-04	333	66	7	int:PHLPP1
Interaction	GJA1 interactions	DST PIK3R1 KIAA1217 SPTAN1 ANKRD26 TMF1 PLEKHA5 TACC1 BECN1	1.14e-04	583	66	9	int:GJA1
Interaction	RAB4A interactions	PTPN9 DST KIAA1217 SPTAN1 TMF1 FAM91A1 PLEKHA5 TACC1	1.19e-04	457	66	8	int:RAB4A
Interaction	NEUROG3 interactions	DST MYO9A SPTAN1 MYO1B PHF10	1.28e-04	149	66	5	int:NEUROG3
Interaction	PCNT interactions	CEP350 FAM184A DST TCHP SPTAN1 DNM1	1.37e-04	241	66	6	int:PCNT
Interaction	FLOT1 interactions	LIMA1 DST PIK3R1 KIAA1217 SPTAN1 ANKRD26 PLEKHA5 MYO1B	1.56e-04	475	66	8	int:FLOT1
Interaction	RNF19B interactions	PIK3R1 APOL3 FAM91A1 WDR48	1.59e-04	83	66	4	int:RNF19B
Interaction	MYO19 interactions	CHCHD3 LIMA1 MYO5B SPTAN1 DOCK7 MYO1B	1.75e-04	252	66	6	int:MYO19
Interaction	STYK1 interactions	DST PIK3R1 PLEKHA5 MYO1B BECN1	1.84e-04	161	66	5	int:STYK1
Interaction	TMOD1 interactions	LIMA1 MYO5B SPTAN1 MYO1B TACC1	1.84e-04	161	66	5	int:TMOD1
Interaction	YWHAE interactions	LIMA1 DST NRAP MYO9A PIK3R1 SPTAN1 DOCK7 ANKRD26 PLEKHA5 DEPDC5 SMC5 TMCC1 WDR48	1.86e-04	1256	66	13	int:YWHAE
Interaction	YWHAH interactions	CEP350 LIMA1 DST MYO9A KIAA1217 SPTAN1 DOCK7 ANKRD26 PLEKHA5 RIMS1 BECN1 TMCC1	2.14e-04	1102	66	12	int:YWHAH
Interaction	DIRAS3 interactions	DST SPTAN1 ANKRD26 FAM91A1 PLEKHA5 BECN1	2.16e-04	262	66	6	int:DIRAS3
Interaction	CALD1 interactions	LIMA1 DST SPTAN1 LAMB1 MYO1B SMC5	2.29e-04	265	66	6	int:CALD1
Interaction	RHOH interactions	CHCHD3 ABCB7 DST PIK3R1 SPTAN1 ANKRD26 FAM91A1 PLEKHA5	2.59e-04	512	66	8	int:RHOH
Interaction	LZTS2 interactions	CHCHD3 FAM184A TCHP MYO9A PIK3R1 KIAA1217 SPTAN1 PLEKHA5	2.59e-04	512	66	8	int:LZTS2
Interaction	RND3 interactions	DST PIK3R1 KIAA1217 SPTAN1 ANKRD26 PLEKHA5	2.69e-04	273	66	6	int:RND3
Interaction	HCN4 interactions	HCN4 HCN1	3.75e-04	9	66	2	int:HCN4
Interaction	STIL interactions	CEP350 TCHP KIAA1217 ANKRD26 C6orf141	3.96e-04	190	66	5	int:STIL
Interaction	SFN interactions	CEP350 LIMA1 DST MYO9A SPTAN1 DOCK7 ANKRD26 PLEKHA5 TMCC1	4.05e-04	692	66	9	int:SFN
Interaction	SPICE1 interactions	CEP350 FAM184A TCHP PLEKHA5 TGM5	4.06e-04	191	66	5	int:SPICE1
Interaction	KCNE3 interactions	CEP350 DST PIK3R1 ANKRD26 PLEKHA5 FAM199X	4.14e-04	296	66	6	int:KCNE3
Interaction	PARD3 interactions	DST TCHP KIAA1217 ANKRD26 PLEKHA5 MYO1B	4.29e-04	298	66	6	int:PARD3
Interaction	EZR interactions	LIMA1 DST PIK3R1 SPTAN1 DOCK7 ANKRD26 PLEKHA5 MYO1B	4.33e-04	553	66	8	int:EZR
Interaction	CYFIP1 interactions	LIMA1 PTPN9 PIK3R1 SPTAN1 DNM1 SMC5	4.68e-04	303	66	6	int:CYFIP1
Interaction	VCL interactions	LIMA1 DST NRAP SPTAN1 ASCC2 PLEKHA5	4.85e-04	305	66	6	int:VCL
Interaction	DISC1 interactions	CEP350 LIMA1 ABCB7 DST SPTAN1 SMC5 ZNF365	4.98e-04	429	66	7	int:DISC1
Interaction	PLEC interactions	LIMA1 DST MYO9A SPTAN1 PLEKHA5 MYO18B C6orf141	5.05e-04	430	66	7	int:PLEC
Interaction	PCM1 interactions	CEP350 FAM184A TCHP MYO9A KIAA1217 ANKRD26 SMC5	5.33e-04	434	66	7	int:PCM1
Interaction	LYN interactions	LIMA1 DST PIK3R1 KIAA1217 SPTAN1 DOCK7 ANKRD26 PLEKHA5 MYO1B	5.40e-04	720	66	9	int:LYN
Interaction	RAB35 interactions	DST PIK3R1 SPTAN1 DOCK7 ANKRD26 FAM91A1 PLEKHA5 TACC1	5.48e-04	573	66	8	int:RAB35
Interaction	RAB3IP interactions	CHCHD3 LIMA1 HCN1 PLEKHA5	5.52e-04	115	66	4	int:RAB3IP
Interaction	HCN3 interactions	HCN4 HCN1	5.70e-04	11	66	2	int:HCN3
Interaction	LATS1 interactions	CEP350 TCHP KIAA1217 SPTAN1 ANKRD26 PLEKHA5 MYO1B	5.79e-04	440	66	7	int:LATS1
Interaction	FGD5 interactions	LIMA1 DST SPTAN1 DOCK7 MYO1B	5.86e-04	207	66	5	int:FGD5
Interaction	SYNE3 interactions	CEP350 DST TCHP KIAA1217 ANKRD26 LAMB1 TACC1	6.10e-04	444	66	7	int:SYNE3
Interaction	H2BC9 interactions	CEP350 DST SPTAN1 DEPDC5 WDFY3 TEX15 SMC5	6.27e-04	446	66	7	int:H2BC9
Interaction	RHOT2 interactions	CHCHD3 DST CENPF KIAA1217 TACC1 WDFY3	6.34e-04	321	66	6	int:RHOT2
Interaction	MED4 interactions	CEP350 FAM184A DST TCHP SPTAN1 ANKRD26 FAM91A1	6.61e-04	450	66	7	int:MED4
Interaction	LRRC39 interactions	LIMA1 MYO5B	6.83e-04	12	66	2	int:LRRC39
Interaction	SLC9A2 interactions	PIK3R1 SPTAN1	6.83e-04	12	66	2	int:SLC9A2
Interaction	GJD3 interactions	DST SPTAN1 ANKRD26 TMF1 FAM91A1 PLEKHA5 TACC1	6.96e-04	454	66	7	int:GJD3
Interaction	PPM1H interactions	LIMA1 TMF1 FAM91A1 PLEKHA5	7.11e-04	123	66	4	int:PPM1H
Interaction	ACTB interactions	LIMA1 DST NRAP TCHP SPTAN1 TMCC2 MYO1B MYO18B DNM1 SMC5 PHF10	7.25e-04	1083	66	11	int:ACTB
Cytoband	Ensembl 112 genes in cytogenetic band chr22q12	APOL3 ASCC2 DEPDC5 MYO18B	3.76e-04	235	66	4	chr22q12
Cytoband	22q12.1	ASCC2 MYO18B	9.82e-04	32	66	2	22q12.1
Cytoband	9q34.11	SPTAN1 CFAP157	2.68e-03	53	66	2	9q34.11
GeneFamily	Transmembrane and coiled-coil domain containing	TMCC2 TMCC1	1.73e-05	3	44	2	774
GeneFamily	Cyclic nucleotide gated channels	HCN4 HCN1	2.57e-04	10	44	2	250
GeneFamily	LIM domain containing	LIMA1 NRAP	9.07e-03	59	44	2	1218
GeneFamily	EF-hand domain containing	DST SPTAN1 TBC1D8B	1.61e-02	219	44	3	863
GeneFamily	WD repeat domain containing	EML6 WDFY3 WDR48	2.57e-02	262	44	3	362
Coexpression	GSE22611_UNSTIM_VS_2H_MDP_STIM_MUTANT_NOD2_TRANSDUCED_HEK293T_CELL_DN	LIMA1 ASCC2 TMF1 TAF2 SMC5 METTL6	7.52e-06	186	66	6	M8175
Coexpression	LAKE_ADULT_KIDNEY_C13_THICK_ASCENDING_LIMB	MYO9A KIAA1217 ANKRD26 LAMB1 TACC1	2.02e-05	131	66	5	M39232
Coexpression	DAZARD_RESPONSE_TO_UV_NHEK_DN	CEP350 DST CENPF WDFY3 SMC5 TMCC1	1.09e-04	300	66	6	M8702
Coexpression	GSE9988_ANTI_TREM1_VS_VEHICLE_TREATED_MONOCYTES_DN	TCHP APOL3 DEPDC5 TACC1 DENND11	1.40e-04	197	66	5	M5853
Coexpression	GSE3982_CTRL_VS_PMA_STIM_EOSINOPHIL_UP	CENPF TMCC2 ANKRD26 TMF1 PLEKHA5	1.40e-04	197	66	5	M5363
Coexpression	GSE14308_NAIVE_CD4_TCELL_VS_INDUCED_TREG_UP	PIK3R1 KIAA1217 ANKRD26 FAM199X SMC5	1.47e-04	199	66	5	M3391
Coexpression	GSE5589_WT_VS_IL6_KO_LPS_AND_IL6_STIM_MACROPHAGE_45MIN_DN	LIMA1 MYO9A DOCK7 PLEKHA5 C6orf141	1.47e-04	199	66	5	M6646
Coexpression	GSE40666_UNTREATED_VS_IFNA_STIM_STAT4_KO_EFFECTOR_CD8_TCELL_90MIN_DN	MYO9A TMF1 MYO1B DENND11 TBC1D8B	1.47e-04	199	66	5	M9236
Coexpression	GSE12845_NAIVE_VS_DARKZONE_GC_TONSIL_BCELL_DN	CEP350 PTPN9 SPTAN1 ANKRD26 DEPDC5	1.51e-04	200	66	5	M3202
Coexpression	GSE17721_LPS_VS_CPG_16H_BMDC_DN	GDAP1L1 KIAA1217 MYO1B TEX15 PHF10	1.51e-04	200	66	5	M4009
Coexpression	GSE17721_CTRL_VS_LPS_0.5H_BMDC_UP	ABCB7 CENPF HCN1 ASCC2 MYO1B	1.51e-04	200	66	5	M3679
Coexpression	GSE10239_NAIVE_VS_MEMORY_CD8_TCELL_UP	ABCB7 FAM91A1 TAF2 SMC5 MINDY2	1.51e-04	200	66	5	M3048
Coexpression	BERENJENO_TRANSFORMED_BY_RHOA_REVERSIBLY_UP	PIK3R1 DNM1	1.73e-04	8	66	2	M16834
Coexpression	HE_LIM_SUN_FETAL_LUNG_C2_DC1_CELL	LIMA1 DST MYO9A ZNF366 APOL3 PLEKHA5	1.77e-04	328	66	6	M45723
ToppCell	renal_medulla_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	MYO9A KIAA1217 EML6 LAMB1 TACC1 WDFY3	3.74e-07	189	66	6	830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCell	facs-Brain_Myeloid-Hippocampus\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DST PIK3R1 FAM91A1 MYO1B TACC1 MYO18B	4.49e-07	195	66	6	a1478021a3ed0e779716393124ca2a7770c433b7
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HCN1 SPTAN1 EML6 PLEKHA5 RIMS1 DNM1	4.91e-07	198	66	6	8ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-1m-Neuronal-Interneuron\|1m / Sample Type, Dataset, Time_group, and Cell type.	CEP350 GDAP1L1 DST HCN4 SPTAN1 TMCC2	5.21e-07	200	66	6	fc839e9c33ea1d4ee0f42f21fd32a54e7cbe1f5a
ToppCell	PBMC-Control-Myeloid-cDC-cDC-cDC_11\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	LIMA1 DST ZNF366 HCN1 PLEKHA5	4.39e-06	163	66	5	a09449a502627aa369db600dba5bda93de7ce5c0
ToppCell	PBMC-Control-Myeloid-cDC-cDC-cDC_11\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	LIMA1 DST ZNF366 HCN1 PLEKHA5	4.52e-06	164	66	5	ed888b55d9c685096fd785878fcb264f4fee88d6
ToppCell	TCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma-Intrahepatic-2\|TCGA-Bile_Duct / Sample_Type by Project: Shred V9	HCN4 MYO9A TMCC2 TACC1 MINDY2	5.08e-06	168	66	5	c70bf73bb800e4722cedc35bbc17ea3113d1012d
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FAM184A MYO5B KIAA1217 PLEKHA5 MYO1B	5.86e-06	173	66	5	b799c06a6a5754668e789f70c0c8bc1508568575
ToppCell	PND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYO5B EML6 DOCK7 TEX15 GPR179	6.20e-06	175	66	5	96219e58dcb327fd27190be78193e7a0d611e62b
ToppCell	PND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYO5B EML6 DOCK7 TEX15 GPR179	6.20e-06	175	66	5	cb974fbebe8cb58c7d3f7defabb4e056f2fee5fa
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma\|TCGA-Brain / Sample_Type by Project: Shred V9	DST SPTAN1 ANKRD26 WDFY3 DENND11	6.55e-06	177	66	5	e8ab340b20cd41554c3841fe980e078e878af35f
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EML6 DOCK7 MYO1B ZNF365 FYB2	7.11e-06	180	66	5	788d5fbf688365b5d92d3aa19b9f8e9448f8be5a
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|LV / Chamber and Cluster_Paper	DST NRAP PLEKHA5 MYO18B FYB2	7.91e-06	184	66	5	ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like_Prolif-E\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MYO5B HCN4 CENPF TEX15 TGM5	8.78e-06	188	66	5	0476d7ee3e0ce78c3c5b111e9ade01098f9ea7ec
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	EML6 DOCK7 LAMB1 MYO1B FYB2	9.01e-06	189	66	5	8ff3c3232eff9de4b5c9b22ecb82bc509d773f58
ToppCell	(5)_Fibroblasts-(5)_Fibroblast-C_(Myofibroblast)\|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)	FAM184A DST PIK3R1 LAMB1 TACC1	9.24e-06	190	66	5	71e112dfb8c3190fe0286b45a046ea789eb6a8db
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEP350 LIMA1 TMF1 MYO1B SMC5	9.48e-06	191	66	5	60c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEP350 LIMA1 TMF1 MYO1B SMC5	9.48e-06	191	66	5	973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCell	facs-Brain_Myeloid-Hippocampus-3m-Myeloid\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEP350 DST PIK3R1 TMF1 TACC1	9.97e-06	193	66	5	06b65110db974f4ef90d3511ff34428976a52c9c
ToppCell	facs-Brain_Myeloid-Hippocampus-3m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEP350 DST PIK3R1 TMF1 TACC1	9.97e-06	193	66	5	9c16032bc03df8760ae199e8f19fdafa4c3f1827
ToppCell	facs-Brain_Myeloid-Hippocampus-3m\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEP350 DST PIK3R1 TMF1 TACC1	9.97e-06	193	66	5	a4f91bca5eaa985982d33a528f7566ffde154d47
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LIMA1 DST KIAA1217 PLEKHA5 C6orf141	9.97e-06	193	66	5	739fb2a57772a800a2e94bdd6c71285bb2c162a7
ToppCell	facs-Brain_Myeloid-Hippocampus-3m-Myeloid-nan\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEP350 DST PIK3R1 TMF1 TACC1	9.97e-06	193	66	5	b39d7feaac4ff8f7409cd3d15e8f3c6391367275
ToppCell	COVID-19-Heart-CM_2\|Heart / Disease (COVID-19 only), tissue and cell type	DST NRAP PLEKHA5 MYO18B FYB2	1.05e-05	195	66	5	75fc81bddb246dca3b437fb60827b1d4fe416405
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HCN1 EML6 PLEKHA5 RIMS1 DNM1	1.07e-05	196	66	5	676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCell	primary_auditory_cortex_(A1C)-Neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HCN1 EML6 PLEKHA5 RIMS1 DNM1	1.13e-05	198	66	5	6d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HCN1 EML6 PLEKHA5 RIMS1 DNM1	1.13e-05	198	66	5	4ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCell	Parenchymal-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FAM184A MYO5B MYO9A KIAA1217 MYO1B	1.16e-05	199	66	5	5cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCell	Neuronal\|World / cells hierarchy compared to all cells using T-Statistic	HCN1 EML6 PLEKHA5 RIMS1 DNM1	1.18e-05	200	66	5	48d801219bc771d6c7e151dc88ca4c179988de85
ToppCell	critical-Epithelial-FOXN4+\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	CEP350 CENPF TACC1 SMC5 PHF10	1.18e-05	200	66	5	f39db4250ce220a3eb58edee3f7fc3671701d46f
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD8-Tnaive/CM_CD8\|GI_small-bowel / Manually curated celltypes from each tissue	FAM184A TMCC2 C6orf141 CFAP157	5.73e-05	141	66	4	b2857b73fd754b879b922c7720b5ac3024976822
ToppCell	PBMC-Severe-Myeloid-cDC-cDC-cDC_11\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	DST ZNF366 PLEKHA5 TEX15	8.07e-05	154	66	4	5967a0a33456d5930fc492a700ebb015ac050abb
ToppCell	PBMC-Severe-Myeloid-cDC-cDC-cDC_11\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DST ZNF366 PLEKHA5 TEX15	8.27e-05	155	66	4	fab281db4c275d51240b122be78713c839ba5a95
ToppCell	COVID-19_Severe-NK_CD56bright\|COVID-19_Severe / disease group, cell group and cell class	CELSR3 PIK3R1 DENND11 CFAP157	9.13e-05	159	66	4	9e2067f0d76769717f7048dab505fadd36bbb83e
ToppCell	COVID-19_Severe-multiplets\|World / disease group, cell group and cell class	CENPF ZNF366 TEX15 TGM5	1.00e-04	163	66	4	6db4271c2d47a9c333964f36d2c32207115e52cd
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_11\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	LIMA1 DST ZNF366 PLEKHA5	1.08e-04	166	66	4	b1bebcbe17386cb102b11d551e62d46156ce0c68
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_11\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	LIMA1 DST ZNF366 PLEKHA5	1.10e-04	167	66	4	e44743b20a7435c579d8e999ddc4ca119d6753f2
ToppCell	Control-Epithelial_cells-ECM-high_epithelial\|Control / group, cell type (main and fine annotations)	DST MYO1B TACC1 FYB2	1.18e-04	170	66	4	e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCell	10x3'2.3-week_12-13-Myeloid_DC-DC-DC1\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	DST ZNF366 APOL3 SCNN1D	1.21e-04	171	66	4	04346d4eb726875e3537e215ea081a0318ca4ddd
ToppCell	tumor_Lymph_Node_/_Brain-T/NK_cells-CD8+/CD4+_Mixed_Th\|T/NK_cells / Location, Cell class and cell subclass	MYO5B MYO9A SCNN1D WDFY3	1.26e-04	173	66	4	42c911ed16fabdabef063830e8407192d8bde950
ToppCell	Bac-SEP-Myeloid-cDC1\|Bac-SEP / Disease, Lineage and Cell Type	DST ZNF366 PLEKHA5 TGM5	1.26e-04	173	66	4	f88269327441858ddb8c49b9dd619b76fd53b1da
ToppCell	Control-Epithelial_cells-AT1\|Control / group, cell type (main and fine annotations)	DST MYO5B MYO1B FYB2	1.29e-04	174	66	4	548d7f2b958a2bfd2c95eb049ceaab55a559c77d
ToppCell	Thalamus-Neuronal-Excitatory\|Thalamus / BrainAtlas - Mouse McCarroll V32	CELSR3 HCN4 RIMS1 TEX15	1.35e-04	176	66	4	d2bbf13d21fb7582d7e5f90cd61a4ebe1cfccd66
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Epithelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CELSR3 CENPF KLKB1 TTC19	1.41e-04	178	66	4	6178706db4a855d72abc156537604d575624df56
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Epithelial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CELSR3 CENPF KLKB1 TTC19	1.41e-04	178	66	4	f02076ece0fa899e620971c887ad4da7f48684ed
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-enteroendocrine_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GDAP1L1 CELSR3 HCN4 TMCC2	1.41e-04	178	66	4	30ca37f70d267cc9b40ca3e211f16d30360c3e6b
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FAM184A MYO5B KIAA1217 MYO1B	1.44e-04	179	66	4	cb38b54261a7af5ee3347e64c8aa880a77ed0763
ToppCell	PCW_10-12-Endothelial-Endothelial_mature-lymphatic\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	APOL3 FBXO39 C6orf141 KLKB1	1.44e-04	179	66	4	ab3d08b51cd7a37582305615ee221c7a2af83b40
ToppCell	PCW_10-12-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	APOL3 FBXO39 C6orf141 KLKB1	1.44e-04	179	66	4	35fe9961e228ce255e3317fc244efa35b5adbf8b
ToppCell	Control-Epithelial-Goblet\|Control / Disease state, Lineage and Cell class	MYO5B KIAA1217 RIMS1 FYB2	1.47e-04	180	66	4	5293d23b8b8ea587239ffde561b70bad01632521
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HCN1 PLEKHA5 RIMS1 DNM1	1.47e-04	180	66	4	f6a2208960d0df1500c974cc44c3c054cd7475a9
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MYO5B KIAA1217 MYO1B KLKB1	1.50e-04	181	66	4	bd7e9437839bca543ca5945df43d6525e6a312a8
ToppCell	Healthy-multiplets\|World / disease group, cell group and cell class	LIMA1 ZNF366 PLEKHA5 TGM5	1.50e-04	181	66	4	f8dbac3cd500cc8d80853312b00d124c27b8fd85
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L2-4_RORB_GRIK1\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PIK3R1 LAMB1 MYO1B ZNF365	1.50e-04	181	66	4	57994ff4ecffb15653aee00644d9f887f5e3461d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EML6 DOCK7 MYO1B FYB2	1.54e-04	182	66	4	f96095b81188b52db8fcfca4837129cfcd9bd7b7
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MYO5B KIAA1217 MYO1B KLKB1	1.57e-04	183	66	4	d2074b13b4831ec18c81273d9a1ff673c3f6a16d
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	EML6 MYO1B MYO18B FYB2	1.57e-04	183	66	4	b5ede5a0048c585b73c00e88aeddbcaf669347b1
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EML6 LAMB1 MYO1B FYB2	1.57e-04	183	66	4	d340ab5a77e8d819a1dfb4ca3e9a4b9bc988923c
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1-D122\|Adult / Lineage, Cell type, age group and donor	DST MYO5B MYO1B FYB2	1.60e-04	184	66	4	561592edc3083fad41b91811151b442207c65dd9
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DST MYO5B MYO1B FYB2	1.63e-04	185	66	4	1c222f7285d6e3dae0354dc7e853ddc0ea55e63e
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1-D175\|Adult / Lineage, Cell type, age group and donor	DST MYO5B MYO1B ZNF365	1.63e-04	185	66	4	32b4e68e551d435a732f253f6ad83408c759a642
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	EML6 DOCK7 MYO18B FYB2	1.63e-04	185	66	4	d602a9b35e86e6f2a14a58e40fc4fb97f5fa3b08
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	NRAP PLEKHA5 MYO18B FYB2	1.63e-04	185	66	4	6baccb26f999145e51b91d94315bf8d4655bef31
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MYO9A EML6 LAMB1 WDFY3	1.67e-04	186	66	4	5c4ffe4e4d5536ae9f8794277fe032c693e7dd56
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MYO5B LAMB1 PLEKHA5 DNM1	1.67e-04	186	66	4	b87acc80b7baa41681e4ed11d5537b9fbf5832f5
ToppCell	Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	HCN4 HCN1 EML6 RIMS1	1.67e-04	186	66	4	b45cce768e4bf91da194fd9660cab7520dfb15ac
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MYO5B PLEKHA5 WDFY3 DNM1	1.70e-04	187	66	4	9d77ca45f7563bd6f2a0c1be5d99d93ad30983f7
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DST MYO5B MYO1B FYB2	1.70e-04	187	66	4	d4b0afd9b92c47c8aa348bbd1af7eb54c3d478f2
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	EML6 LAMB1 MYO1B FYB2	1.70e-04	187	66	4	f6217d0dd425eac76900b44a4e48f45475f3ac36
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EML6 DOCK7 MYO1B FYB2	1.70e-04	187	66	4	e3095455d2f255854f339f6b05fa87852af0700f
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EML6 DOCK7 MYO1B FYB2	1.77e-04	189	66	4	3a295c215b5c18e7c673f92b7af5be523421682c
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	NRAP KIAA1217 MYO18B FYB2	1.77e-04	189	66	4	0a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK7 LAMB1 MYO1B FYB2	1.81e-04	190	66	4	4836ea19308d2a96694f12ab0653b7ce7b101d2f
ToppCell	COVID-19-Epithelial_cells-Airway_goblet\|COVID-19 / group, cell type (main and fine annotations)	MYO5B KIAA1217 RIMS1 FYB2	1.81e-04	190	66	4	51ca9ef4df3220487152fcf684147730637c7cc1
ToppCell	facs-Heart-LV-24m-Mesenchymal-ventricular_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRAP MYO5B CENPF MYO18B	1.85e-04	191	66	4	543da1197c7e62f2c9cbd4a51414bbaaa6d1a92f
ToppCell	PND01-03-samps-Mesenchymal-Matrix_fibroblast-MatrixFB-A\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	PIK3R1 PLEKHA5 TACC1 METTL6	1.85e-04	191	66	4	e7c605b56934d1383237c1f946dbccef25d91368
ToppCell	facs-Heart-LV-24m-Mesenchymal-ventricular_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRAP MYO5B CENPF MYO18B	1.85e-04	191	66	4	9d7d680da3979e256191b534ebd14c5383e0cf93
ToppCell	Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|World / Lineage, Cell type, age group and donor	FAM184A MYO5B KIAA1217 MYO1B	1.85e-04	191	66	4	d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCell	Children_(3_yrs)-Epithelial\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FAM184A MYO5B KIAA1217 MYO1B	1.85e-04	191	66	4	e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	EML6 LAMB1 MYO1B FYB2	1.85e-04	191	66	4	96b78b4e819ea6052334bfcbc7abbf35897df885
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEP350 LIMA1 TMF1 MYO1B	1.85e-04	191	66	4	09db184cb90fe282a14474d7217068c58092c6f8
ToppCell	Epithelial\|World / Lineage, Cell type, age group and donor	FAM184A MYO5B KIAA1217 MYO1B	1.88e-04	192	66	4	499e8893afea5e6d3371e0bd018f7e86a524d669
ToppCell	COPD-Epithelial\|COPD / Disease state, Lineage and Cell class	MYO5B KIAA1217 MYO1B FYB2	1.88e-04	192	66	4	0644fad5df18f0021f6f49cca996d8cf47f972ff
ToppCell	droplet-Heart-nan-24m-Mesenchymal-cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRAP MYO5B HCN1 MYO18B	1.88e-04	192	66	4	f6a4e348406a852ace9fb21db8fbdff539217645
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	EML6 LAMB1 MYO1B FYB2	1.88e-04	192	66	4	fd08ae787e936cfdb1ab8f19b0fd63005b462709
ToppCell	human_hepatoblastoma-Tumor_cells-T8\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	DST MYO1B KLKB1 FYB2	1.88e-04	192	66	4	e785135262f4c9cc66c403bf362bb34643b212c5
ToppCell	Adult-Epithelial\|Adult / Lineage, Cell type, age group and donor	FAM184A MYO5B KIAA1217 MYO1B	1.88e-04	192	66	4	efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCell	droplet-Heart-nan-24m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRAP MYO5B HCN1 MYO18B	1.88e-04	192	66	4	1a0c25106ae08eac912a4edd5fc1a3ee776f69c2
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FAM184A MYO9A TTC14 TACC1	1.88e-04	192	66	4	ee27d27e3d269764dbe8711d0b37ff9331a298a9
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	EML6 LAMB1 MYO1B FYB2	1.88e-04	192	66	4	bae236c9f1fac77bce28d0a9cf090100d391ff77
ToppCell	NS-moderate-d_0-4\|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	FAM184A PLEKHA5 FYB2 CFAP157	1.92e-04	193	66	4	ea345d34440b25f65358a53dc72831998d1c3620
ToppCell	COVID-19-kidney-CD-PC\|kidney / Disease (COVID-19 only), tissue and cell type	EML6 LAMB1 MYO1B FYB2	1.92e-04	193	66	4	738689d009e4b118d7ce3171a207294b95cbe78b
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LIMA1 DOCK7 MYO1B MINDY2	1.96e-04	194	66	4	46070fbb0ee0eb9e1801c43b73a15707471056dc
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LIMA1 EML6 MYO1B FYB2	1.96e-04	194	66	4	4579b4a44f7c731553a284843c296866027d7c0e
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LIMA1 DOCK7 MYO1B MINDY2	1.96e-04	194	66	4	abacb6a8d7a9003f2f6c2be0305507f1c1c50347
ToppCell	nucseq-Epithelial-Epithelial_Alveolar\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FAM184A MYO5B MYO9A MYO1B	1.96e-04	194	66	4	53f3e49e91b1096f3226010e2de767efb490dfe4
ToppCell	moderate-Epithelial-FOXN4+\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	CEP350 CENPF SMC5 PHF10	1.96e-04	194	66	4	dff3fb10372053951d41e0ccd41aac3ece6009bd
ToppCell	10x5'v1-week_17-19-Endothelial-stroma-sinusoidal_EC\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	KIAA1217 LAMB1 FBXO39 C6orf141	2.00e-04	195	66	4	22a481927147ec4ae9d59e6af7c87df0e9cb51e4
ToppCell	PBMC-Control-cDC_11\|Control / Compartment, Disease Groups and Clusters	LIMA1 ZNF366 APOL3 PLEKHA5	2.00e-04	195	66	4	74d560ff0f47512441c305885c5c16272f711b8e
ToppCell	356C-Epithelial_cells-Epithelial-I_(AT1)\|356C / Donor, Lineage, Cell class and subclass (all cells)	DST MYO5B MYO1B FYB2	2.00e-04	195	66	4	07a3ef6b0f1201fe2bcb9ea426b8f7a69beb4904
Drug	AC1L1KMJ	LIMA1 DST MYO5B PIK3R1 SPTAN1 LAMB1 MYO1B DNM1 WDR48	9.10e-06	476	66	9	CID000030956
Drug	resveratrol; Down 200; 10uM; MCF7; HT_HG-U133A_EA	PTPN9 CENPF PIK3R1 PLEKHA5 TACC1 WDR48	1.21e-05	176	66	6	958_DN
Drug	formycin triphosphate	MYO5B MYO9A MYO1B MYO18B	1.45e-05	51	66	4	CID000122274
Drug	B0683	MYO5B MYO9A TMF1 MYO1B MYO18B	2.29e-05	117	66	5	CID006398969
Drug	purealin	MYO5B MYO9A MYO1B MYO18B	2.43e-05	58	66	4	CID006419303
Disease	sick sinus syndrome (implicated_via_orthology)	HCN4 HCN1	1.39e-05	3	64	2	DOID:13884 (implicated_via_orthology)
Disease	EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 1	HCN1 DNM1	6.91e-05	6	64	2	C3463992
Disease	diet measurement	CHCHD3 DST PIK3R1 HCN1 KIAA1217 ASCC2 DEPDC5 RIMS1 TEX15 MINDY2	8.19e-05	1049	64	10	EFO_0008111
Disease	alcohol-related neurodevelopmental disorder (implicated_via_orthology)	TMCC2 TMCC1	1.29e-04	8	64	2	DOID:0050667 (implicated_via_orthology)
Disease	X-linked infantile spasms	HCN1 DNM1	1.29e-04	8	64	2	C4552072
Disease	1-stearoyl-2-linoleoyl-GPI (18:0/18:2) measurement	MYO5B DOCK7	3.56e-04	13	64	2	EFO_0800413
Disease	Tremor, Rubral	ABCB7 HCN1	5.45e-04	16	64	2	C0750940
Disease	Ataxia, Appendicular	ABCB7 HCN1	5.45e-04	16	64	2	C0750937
Disease	Ataxia, Motor	ABCB7 HCN1	5.45e-04	16	64	2	C0278161
Disease	Abnormal coordination	ABCB7 HCN1	5.45e-04	16	64	2	C0520966
Disease	Ataxia, Truncal	ABCB7 HCN1	5.45e-04	16	64	2	C0427190
Disease	Ataxia, Sensory	ABCB7 HCN1	5.45e-04	16	64	2	C0240991
Disease	Neurodevelopmental Disorders	RIMS1 WDFY3 DNM1	1.10e-03	93	64	3	C1535926
Disease	unipolar depression, neuroticism measurement	ZNF366 KIAA1217	1.24e-03	24	64	2	EFO_0003761, EFO_0007660
Disease	Ataxia	ABCB7 HCN1	1.35e-03	25	64	2	C0004134
Disease	lysophosphatidylcholine 18:2 measurement	RIMS1 ZNF365	1.69e-03	28	64	2	EFO_0010361
Disease	Alzheimer disease, polygenic risk score	DST ZNF366 HCN1 ASCC2 RIMS1 MINDY2	1.69e-03	586	64	6	EFO_0030082, MONDO_0004975
Disease	Drug habituation	CHCHD3 FAM184A ZNF366	2.02e-03	115	64	3	C0013170
Disease	Substance-Related Disorders	CHCHD3 FAM184A ZNF366	2.02e-03	115	64	3	C0236969
Disease	Drug abuse	CHCHD3 FAM184A ZNF366	2.02e-03	115	64	3	C0013146
Disease	Drug Use Disorders	CHCHD3 FAM184A ZNF366	2.02e-03	115	64	3	C0013222
Disease	Drug Dependence	CHCHD3 FAM184A ZNF366	2.02e-03	115	64	3	C1510472
Disease	Substance Dependence	CHCHD3 FAM184A ZNF366	2.02e-03	115	64	3	C0038580
Disease	Substance Use Disorders	CHCHD3 FAM184A ZNF366	2.02e-03	115	64	3	C0038586
Disease	Organic Mental Disorders, Substance-Induced	CHCHD3 FAM184A ZNF366	2.02e-03	115	64	3	C0029231
Disease	Prescription Drug Abuse	CHCHD3 FAM184A ZNF366	2.02e-03	115	64	3	C4316881
Disease	Substance abuse problem	CHCHD3 FAM184A ZNF366	2.07e-03	116	64	3	C0740858

Protein segments in the cluster

Peptide	Gene	Start	Entry
AQDYLARVKQEEQRY	TACC1	716	O75410
AAQRQRYEQYSVVVE	ASCC2	581	Q9H1I8
RQYQYENEKAEREVV	ANKRD26	1206	Q9UPS8
QVRKQENEFRDYAYN	CFAP157	171	Q5JU67
VNEAKRTQQEYYERE	FAM184A	446	Q8NB25
NARQKQGIYEEYEDI	PTPN9	296	P43378
NIISDYDQIIDYVER	GDAP1L1	106	Q96MZ0
YEDFYKVVVQNERRE	DEPDC5	251	O75140
SVEEQIKRNRYYDED	LIMA1	741	Q9UHB6
QLQSDVRYTEDYEQQ	NRAP	221	Q86VF7
QAYLEETYRQAKERE	GPR179	856	Q6PRD1
REYKEKREQYSDFNQ	NLRP11	476	P59045
QYYQELLKSAEREEQ	DST	1046	Q03001
TEQRNVYKDYRQLEL	DNM1	591	Q05193
REYEKQVVLYSIRNQ	FAM91A1	31	Q658Y4
RLDQEEAQYQREYSE	BECN1	221	Q14457
EAQYQREYSEFKRQQ	BECN1	226	Q14457
NDEQVEYIEYLSRKV	FAM199X	186	Q6PEV8
ARIYTNRYETNEEDK	FBXO39	401	Q8N4B4
KYEDNQRYLEDKAQE	LAMB1	1746	P07942
EYNTQFQEKSREYDR	PIK3R1	451	P27986
DSSRRQYQEKYKQVE	HCN4	521	Q9Y3Q4
YEEVVNEYVFRETVN	METTL6	236	Q8TCB7
YRVTTEQYQKAAEEV	CHCHD3	156	Q9NX63
DEEKQRKEEDYQTRY	RIMS1	341	Q86UR5
QEKERQRITDHYKEY	PHF10	166	Q8WUB8
DSSRRQYQEKYKQVE	HCN1	401	O60741
DQKEYQRELERNYHR	DOCK7	2086	Q96N67
DTNKQYEVEIQTYRE	CENPF	2716	P49454
KYVLVRVEDYQVTQE	C6orf141	156	Q5SZD1
EKRELYDVYVDNQNV	DENND11	326	A4D1U4
YDTDEVRQYIVRQQE	CEP350	591	Q5VT06
RTYAAIEDEYVQQKD	APOL3	131	O95236
RYVETQAKENAYDLE	EIF3K	31	Q9UBQ5
EECQKRYQDYKITQR	KLKB1	546	P03952
EAQINYDRQVYKEDL	EML6	636	Q6ZMW3
DYEARQEYVIVVQAT	CELSR3	1131	Q9NYQ7
NIVYQELNYRSVEEA	SCNN1D	666	P51172
KQRYLDEAEREKQQY	HMG20B	116	Q9P0W2
EEEDRRASQYYQEQE	MINDY2	551	Q8NBR6
IQANVERKDVADYYE	TEX47	56	Q8TBZ9
QEERYRYERLEEQLN	TMCC2	556	O75069
YQSYERARDIQEAVE	TMCC2	596	O75069
YQLRYERDVVAQQES	TAF2	651	Q6P1X5
ENRELYEDVYKTKNN	FYB2	516	Q5VWT5
IKDESRNVYYELNDV	KIAA1217	236	Q5T5P2
ETVKYFNNERYEAQR	ABCB7	341	O75027
IGNYRTQLYDKQREE	TMED9	61	Q9BVK6
RRQEEQKHDDYVYDI	SLC7A6OS	186	Q96CW6
RERYTQAKEIYQEAL	TTC19	331	Q6DKK2
YQVELENLKDEYVRT	TMF1	866	P82094
QVSYVIRDEVEKYNR	WDR48	16	Q8TAF3
RVELAEKQLEYYQSQ	ZNF365	281	Q70YC5
AVVRDLVDTQYKEYQ	WDFY3	2316	Q8IZQ1
IRESNEKYGNIRYED	TBC1D8B	746	Q0IIM8
KEELYQNLTREQADY	SPTAN1	2426	Q13813
KIAYQSYERARDIQE	TMCC1	536	O94876
QRYRLNTNQGEYERE	TTC14	701	Q96N46
EQENKRYENEYERAR	TCHP	181	Q9BT92
TENYKYEEGSLQERQ	TGM5	441	O43548
QQRESSQYYQRRLEE	MYO18B	2016	Q8IUG5
RVDVNVQIDDSYYVD	ZNF366	231	Q8N895
NIQRDYKETAYVEDR	TEX15	436	Q9BXT5
EYDKLEYDVTVTRNQ	PLEKHA5	721	Q9HAU0
QRNERYKQDVERFYE	SMC5	241	Q8IY18
YRDQFTDQQKLIYEE	MYO1B	926	O43795
EEERSRYQNLVKEYS	MYO5B	1061	Q9ULV0
EKSRLVYQEHNERNY	MYO9A	321	B2RTY4