Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	HOXB9 TCF7 CPHXL TCF7L2 VENTX NEUROD1 HOXC11 FOXN4 NFIB GLI2 ARX ZFHX2 FOXN3 SOX8 TBX1 FOXF1 SMAD1 PROP1	2.56e-06	1271	81	18	GO:0000987
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	HOXB9 TCF7 CPHXL TCF7L2 VENTX NEUROD1 HOXC11 FOXN4 NFIB GLI2 ARX ZFHX2 FOXN3 SOX8 FOXG1 TBX1 FOXF1 SMAD1 PROP1	2.71e-06	1412	81	19	GO:0000981
GeneOntologyMolecularFunction	DNA-binding transcription activator activity, RNA polymerase II-specific	TCF7L2 VENTX NEUROD1 HOXC11 NFIB GLI2 ARX TBX1 FOXF1 SMAD1 PROP1	1.57e-05	560	81	11	GO:0001228
GeneOntologyMolecularFunction	DNA-binding transcription activator activity	TCF7L2 VENTX NEUROD1 HOXC11 NFIB GLI2 ARX TBX1 FOXF1 SMAD1 PROP1	1.73e-05	566	81	11	GO:0001216
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	HOXB9 TCF7 CPHXL TCF7L2 VENTX NEUROD1 HOXC11 NFIB GLI2 ARX ZFHX2 SOX8 TBX1 FOXF1 SMAD1 PROP1	3.35e-05	1244	81	16	GO:0000978
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	HOXB9 TCF7 CPHXL TCF7L2 VENTX NEUROD1 HOXC11 NFIB GLI2 ARX ZFHX2 SOX8 TBX1 FOXF1 SMAD1 PROP1	2.18e-04	1459	81	16	GO:0000977
GeneOntologyBiologicalProcess	cell fate commitment	TCF7L2 NEUROD1 FOXN4 NFIB GLI2 ARX SOX8 PTCH1 FOXG1 TBX1 SMAD1	9.66e-08	338	82	11	GO:0045165
GeneOntologyBiologicalProcess	embryonic morphogenesis	HOXB9 TCF7 TCF7L2 NEUROD1 HOXC11 FOXN4 GLI2 CECR2 TRIOBP SOX8 PTCH1 FOXG1 TBX1 FOXF1 SMAD1	1.20e-07	713	82	15	GO:0048598
GeneOntologyBiologicalProcess	embryonic organ morphogenesis	HOXB9 TCF7 TCF7L2 NEUROD1 HOXC11 FOXN4 GLI2 TRIOBP FOXG1 TBX1 FOXF1	1.41e-07	351	82	11	GO:0048562
GeneOntologyBiologicalProcess	embryonic organ development	HOXB9 TCF7 TCF7L2 NEUROD1 HOXC11 EGFR FOXN4 GLI2 TRIOBP PTCH1 FOXG1 TBX1 FOXF1	3.11e-07	561	82	13	GO:0048568
GeneOntologyBiologicalProcess	animal organ morphogenesis	DLG5 HOXB9 TCF7 TCF7L2 NEUROD1 HOXC11 EGFR FOXN4 NFIB GLI2 TRIOBP FOXN3 SIK3 SOX8 PTCH1 FOXG1 TBX1 FOXF1 PROP1	4.11e-07	1269	82	19	GO:0009887
GeneOntologyBiologicalProcess	positive regulation of transcription by RNA polymerase II	HOXB9 TAF8 TCF7L2 VENTX NEUROD1 HOXC11 EGFR FOXN4 NFIB GLI2 ARX POGZ SOX8 DOT1L ARID5A TBX1 FOXF1 SMAD1 PROP1	1.62e-06	1390	82	19	GO:0045944
GeneOntologyBiologicalProcess	neuron projection development	TANC2 DLG5 PRTG PRDM8 NEUROD1 EGFR NFIB GLI2 CECR2 ARX FBXO7 TRIOBP FRYL ACTL9 PTCH1 CSMD3 PIAS2 FOXG1	2.29e-06	1285	82	18	GO:0031175
GeneOntologyBiologicalProcess	neuron development	TANC2 DLG5 PRTG PRDM8 NEUROD1 EGFR NFIB GLI2 CECR2 ARX FBXO7 TRIOBP KCNQ2 FRYL ACTL9 PTCH1 CSMD3 PIAS2 FOXG1	3.45e-06	1463	82	19	GO:0048666
GeneOntologyBiologicalProcess	digestive tract morphogenesis	TCF7 TCF7L2 EGFR GLI2 FOXF1	3.71e-06	59	82	5	GO:0048546
GeneOntologyBiologicalProcess	central nervous system development	DLG5 PRDM8 TCF7L2 NEUROD1 ATN1 EGFR FOXN4 NFIB GLI2 ARX KCNQ2 SOX8 PTCH1 FOXG1 TBX1 SMAD1 PROP1	3.84e-06	1197	82	17	GO:0007417
GeneOntologyBiologicalProcess	hindgut morphogenesis	TCF7 TCF7L2 GLI2	5.00e-06	9	82	3	GO:0007442
GeneOntologyBiologicalProcess	hindgut development	TCF7 TCF7L2 GLI2	7.12e-06	10	82	3	GO:0061525
GeneOntologyBiologicalProcess	pattern specification process	HOXB9 NEUROD1 HOXC11 FOXN4 GLI2 PTCH1 FOXG1 TBX1 FOXF1 SMAD1 PROP1	7.29e-06	526	82	11	GO:0007389
GeneOntologyBiologicalProcess	negative regulation of DNA-templated transcription	RALGAPA1 PRDM8 ZNF469 TCF7 TCF7L2 ATN1 NFIB GLI2 ARX ZNF318 FOXN3 SOX8 PTCH1 ARID5A FOXG1 TBX1 FOXF1 PROP1	7.50e-06	1399	82	18	GO:0045892
GeneOntologyBiologicalProcess	negative regulation of RNA biosynthetic process	RALGAPA1 PRDM8 ZNF469 TCF7 TCF7L2 ATN1 NFIB GLI2 ARX ZNF318 FOXN3 SOX8 PTCH1 ARID5A FOXG1 TBX1 FOXF1 PROP1	8.60e-06	1413	82	18	GO:1902679
GeneOntologyBiologicalProcess	embryo development	TANC2 HOXB9 TAF8 TCF7 TCF7L2 NEUROD1 HOXC11 EGFR FOXN4 GLI2 CECR2 TRIOBP SOX8 PTCH1 FOXG1 TBX1 FOXF1 SMAD1	1.08e-05	1437	82	18	GO:0009790
GeneOntologyBiologicalProcess	embryonic digestive tract development	TCF7 TCF7L2 GLI2 FOXF1	1.11e-05	35	82	4	GO:0048566
GeneOntologyBiologicalProcess	head development	DLG5 PRDM8 TCF7L2 NEUROD1 EGFR NFIB GLI2 ARX KCNQ2 PTCH1 FOXG1 TBX1 SMAD1 PROP1	1.44e-05	919	82	14	GO:0060322
GeneOntologyBiologicalProcess	negative regulation of transcription by RNA polymerase II	RALGAPA1 ZNF469 TCF7 TCF7L2 ATN1 NFIB GLI2 ARX SOX8 PTCH1 ARID5A FOXG1 TBX1 FOXF1 PROP1	1.51e-05	1053	82	15	GO:0000122
GeneOntologyBiologicalProcess	regionalization	HOXB9 NEUROD1 HOXC11 FOXN4 GLI2 PTCH1 FOXG1 TBX1 FOXF1 PROP1	1.96e-05	478	82	10	GO:0003002
GeneOntologyBiologicalProcess	forebrain development	PRDM8 TCF7L2 NEUROD1 EGFR NFIB GLI2 ARX KCNQ2 FOXG1 PROP1	2.38e-05	489	82	10	GO:0030900
GeneOntologyBiologicalProcess	central nervous system neuron differentiation	PRDM8 FOXN4 NFIB GLI2 ARX PTCH1 FOXG1	2.52e-05	217	82	7	GO:0021953
GeneOntologyBiologicalProcess	neuron fate commitment	FOXN4 NFIB GLI2 FOXG1 TBX1	3.12e-05	91	82	5	GO:0048663
GeneOntologyBiologicalProcess	brain development	DLG5 PRDM8 TCF7L2 NEUROD1 EGFR NFIB GLI2 ARX KCNQ2 PTCH1 FOXG1 SMAD1 PROP1	3.23e-05	859	82	13	GO:0007420
GeneOntologyBiologicalProcess	central nervous system neuron development	PRDM8 NFIB GLI2 ARX FOXG1	4.69e-05	99	82	5	GO:0021954
GeneOntologyBiologicalProcess	epithelium development	DLG5 TCF7 TCF7L2 NEUROD1 EGFR FOXN4 NFIB GLI2 CECR2 ARX TRIOBP EXTL3 SOX8 PTCH1 TBX1 FOXF1 SMAD1	5.45e-05	1469	82	17	GO:0060429
GeneOntologyBiologicalProcess	chordate embryonic development	TANC2 HOXB9 TAF8 TCF7 TCF7L2 HOXC11 EGFR GLI2 CECR2 SOX8 PTCH1 TBX1 FOXF1	5.58e-05	906	82	13	GO:0043009
GeneOntologyBiologicalProcess	dorsal/ventral pattern formation	FOXN4 GLI2 PTCH1 FOXG1 PROP1	6.79e-05	107	82	5	GO:0009953
GeneOntologyBiologicalProcess	embryo development ending in birth or egg hatching	TANC2 HOXB9 TAF8 TCF7 TCF7L2 HOXC11 EGFR GLI2 CECR2 SOX8 PTCH1 TBX1 FOXF1	7.20e-05	929	82	13	GO:0009792
GeneOntologyBiologicalProcess	embryonic digestive tract morphogenesis	TCF7 TCF7L2 FOXF1	7.65e-05	21	82	3	GO:0048557
GeneOntologyBiologicalProcess	embryonic genitalia morphogenesis	TCF7 TCF7L2	9.32e-05	4	82	2	GO:0030538
GeneOntologyBiologicalProcess	branching morphogenesis of an epithelial tube	DLG5 GLI2 SOX8 PTCH1 TBX1 FOXF1	1.39e-04	198	82	6	GO:0048754
GeneOntologyBiologicalProcess	embryonic hindgut morphogenesis	TCF7 TCF7L2	1.55e-04	5	82	2	GO:0048619
GeneOntologyBiologicalProcess	cell morphogenesis involved in neuron differentiation	TANC2 PRTG PRDM8 NFIB GLI2 ARX TRIOBP ACTL9 PTCH1 PIAS2 FOXG1	1.78e-04	748	82	11	GO:0048667
GeneOntologyBiologicalProcess	morphogenesis of an epithelial fold	EGFR GLI2 CECR2	2.05e-04	29	82	3	GO:0060571
GeneOntologyBiologicalProcess	cell morphogenesis	TANC2 PRTG PRDM8 EGFR NFIB GLI2 ARX PALM3 TRIOBP FRYL ACTL9 PTCH1 PIAS2 FOXG1	2.39e-04	1194	82	14	GO:0000902
GeneOntologyBiologicalProcess	epithelial tube morphogenesis	DLG5 FOXN4 GLI2 CECR2 SOX8 PTCH1 TBX1 FOXF1	2.69e-04	421	82	8	GO:0060562
GeneOntologyBiologicalProcess	central nervous system projection neuron axonogenesis	PRDM8 NFIB GLI2	2.76e-04	32	82	3	GO:0021952
GeneOntologyBiologicalProcess	neuron projection morphogenesis	TANC2 PRTG PRDM8 EGFR NFIB GLI2 ARX ACTL9 PTCH1 PIAS2 FOXG1	3.24e-04	802	82	11	GO:0048812
GeneOntologyBiologicalProcess	digestive tract development	TCF7 TCF7L2 EGFR GLI2 FOXF1	3.52e-04	152	82	5	GO:0048565
GeneOntologyBiologicalProcess	telencephalon development	PRDM8 NEUROD1 EGFR NFIB ARX KCNQ2 FOXG1	3.55e-04	332	82	7	GO:0021537
GeneOntologyBiologicalProcess	morphogenesis of a branching epithelium	DLG5 GLI2 SOX8 PTCH1 TBX1 FOXF1	3.57e-04	236	82	6	GO:0061138
GeneOntologyBiologicalProcess	gland development	HOXB9 TCF7L2 EGFR NFIB GLI2 PTCH1 TBX1 FOXF1 PROP1	3.69e-04	558	82	9	GO:0048732
GeneOntologyBiologicalProcess	plasma membrane bounded cell projection morphogenesis	TANC2 PRTG PRDM8 EGFR NFIB GLI2 ARX ACTL9 PTCH1 PIAS2 FOXG1	3.87e-04	819	82	11	GO:0120039
GeneOntologyBiologicalProcess	cell projection morphogenesis	TANC2 PRTG PRDM8 EGFR NFIB GLI2 ARX ACTL9 PTCH1 PIAS2 FOXG1	4.16e-04	826	82	11	GO:0048858
GeneOntologyBiologicalProcess	proximal/distal pattern formation	HOXB9 HOXC11 GLI2	4.27e-04	37	82	3	GO:0009954
GeneOntologyBiologicalProcess	negative regulation of type B pancreatic cell apoptotic process	TCF7L2 NEUROD1	4.30e-04	8	82	2	GO:2000675
GeneOntologyBiologicalProcess	anterior/posterior pattern specification	HOXB9 NEUROD1 HOXC11 GLI2 TBX1 FOXF1	4.55e-04	247	82	6	GO:0009952
GeneOntologyBiologicalProcess	diencephalon development	TCF7L2 GLI2 ARX PROP1	4.57e-04	90	82	4	GO:0021536
GeneOntologyBiologicalProcess	endocrine system development	TCF7L2 NEUROD1 GLI2 TBX1 PROP1	4.58e-04	161	82	5	GO:0035270
GeneOntologyBiologicalProcess	tube morphogenesis	DLG5 TCF7 TCF7L2 EGFR FOXN4 NFIB GLI2 CECR2 SOX8 PTCH1 TBX1 FOXF1 SMAD1	4.71e-04	1125	82	13	GO:0035239
GeneOntologyBiologicalProcess	inner ear development	NEUROD1 GLI2 CECR2 TRIOBP FOXG1 TBX1	5.16e-04	253	82	6	GO:0048839
GeneOntologyBiologicalProcess	regulation of neuron differentiation	NEUROD1 ATN1 GLI2 ZFHX2 SOX8 FOXG1	5.38e-04	255	82	6	GO:0045664
GeneOntologyBiologicalProcess	digestive system development	TCF7 TCF7L2 EGFR GLI2 FOXF1	5.41e-04	167	82	5	GO:0055123
GeneOntologyBiologicalProcess	metanephros development	DLG5 HOXC11 SOX8 PTCH1	5.61e-04	95	82	4	GO:0001656
GeneOntologyBiologicalProcess	morphogenesis of a branching structure	DLG5 GLI2 SOX8 PTCH1 TBX1 FOXF1	5.72e-04	258	82	6	GO:0001763
GeneOntologyBiologicalProcess	neuron fate specification	NFIB GLI2 TBX1	6.22e-04	42	82	3	GO:0048665
GeneOntologyBiologicalProcess	sensory organ development	NEUROD1 EGFR FOXN4 NFIB GLI2 CECR2 TRIOBP SOX8 FOXG1 TBX1	6.22e-04	730	82	10	GO:0007423
GeneOntologyBiologicalProcess	epithelial cell differentiation	DLG5 NEUROD1 NFIB GLI2 ARX TRIOBP EXTL3 SOX8 PTCH1 TBX1 FOXF1	6.41e-04	870	82	11	GO:0030855
GeneOntologyBiologicalProcess	central nervous system neuron axonogenesis	PRDM8 NFIB GLI2	6.66e-04	43	82	3	GO:0021955
GeneOntologyBiologicalProcess	negative regulation of cell differentiation	PRTG TCF7L2 EGFR GLI2 FBXO7 EXTL3 SOX8 PTCH1 FOXG1 TBX1 SMAD1	6.72e-04	875	82	11	GO:0045596
GeneOntologyBiologicalProcess	gland morphogenesis	EGFR NFIB GLI2 PTCH1 PROP1	7.22e-04	178	82	5	GO:0022612
GeneOntologyBiologicalProcess	skeletal system development	HOXB9 HOXC11 NFIB GLI2 FOXN3 SIK3 ARID5A TBX1 SMAD1	7.42e-04	615	82	9	GO:0001501
GeneOntologyBiologicalProcess	regulation of miRNA metabolic process	ZSWIM8 EGFR NFIB SMAD1	7.61e-04	103	82	4	GO:2000628
GeneOntologyBiologicalProcess	pituitary gland development	TCF7L2 GLI2 PROP1	7.62e-04	45	82	3	GO:0021983
GeneOntologyBiologicalProcess	regulation of mesenchymal cell proliferation	NFIB TBX1 FOXF1	7.62e-04	45	82	3	GO:0010464
GeneOntologyBiologicalProcess	tissue morphogenesis	DLG5 EGFR FOXN4 GLI2 CECR2 SOX8 PTCH1 TBX1 FOXF1 SMAD1	7.66e-04	750	82	10	GO:0048729
GeneOntologyBiologicalProcess	nuclear transport	NOP9 NEUROD1 POM121 RGPD8 STRADA KCNQ2 RGPD5	7.68e-04	378	82	7	GO:0051169
GeneOntologyBiologicalProcess	nucleocytoplasmic transport	NOP9 NEUROD1 POM121 RGPD8 STRADA KCNQ2 RGPD5	7.68e-04	378	82	7	GO:0006913
GeneOntologyBiologicalProcess	morphogenesis of an epithelium	DLG5 EGFR FOXN4 GLI2 CECR2 SOX8 PTCH1 TBX1 FOXF1	7.77e-04	619	82	9	GO:0002009
GeneOntologyBiologicalProcess	renal system development	DLG5 HOXC11 GLI2 SOX8 PTCH1 FOXF1 SMAD1	8.68e-04	386	82	7	GO:0072001
GeneOntologyBiologicalProcess	ear development	NEUROD1 GLI2 CECR2 TRIOBP FOXG1 TBX1	9.60e-04	285	82	6	GO:0043583
GeneOntologyBiologicalProcess	axon guidance	PRTG NFIB GLI2 ARX PTCH1 FOXG1	9.60e-04	285	82	6	GO:0007411
GeneOntologyBiologicalProcess	neuron projection guidance	PRTG NFIB GLI2 ARX PTCH1 FOXG1	9.78e-04	286	82	6	GO:0097485
GeneOntologyBiologicalProcess	regulation of epithelial cell proliferation	TCF7L2 EGFR NFIB GLI2 ARX EXTL3 PTCH1 TBX1	9.98e-04	514	82	8	GO:0050678
GeneOntologyBiologicalProcess	ventral spinal cord interneuron fate commitment	FOXN4 GLI2	1.00e-03	12	82	2	GO:0060579
GeneOntologyBiologicalProcess	cell fate commitment involved in pattern specification	FOXN4 GLI2	1.00e-03	12	82	2	GO:0060581
GeneOntologyBiologicalProcess	midgut development	EGFR FOXF1	1.00e-03	12	82	2	GO:0007494
GeneOntologyBiologicalProcess	axon development	PRTG PRDM8 NEUROD1 NFIB GLI2 ARX ACTL9 PTCH1 FOXG1	1.00e-03	642	82	9	GO:0061564
GeneOntologyBiologicalProcess	growth	TAF8 TCF7L2 ATN1 EGFR GLI2 ARX MUC12 EXTL3 SIK3 BCAR1 PTCH1 TBX1 SMAD1	1.12e-03	1235	82	13	GO:0040007
GeneOntologyBiologicalProcess	neural tube development	TCF7 TCF7L2 GLI2 CECR2 PTCH1	1.27e-03	202	82	5	GO:0021915
GeneOntologyBiologicalProcess	miRNA metabolic process	ZSWIM8 EGFR NFIB SMAD1	1.30e-03	119	82	4	GO:0010586
GeneOntologyBiologicalProcess	commissural neuron axon guidance	NFIB PTCH1	1.38e-03	14	82	2	GO:0071679
GeneOntologyBiologicalProcess	ventral spinal cord interneuron differentiation	FOXN4 GLI2	1.38e-03	14	82	2	GO:0021514
GeneOntologyBiologicalProcess	cerebral cortex cell migration	EGFR ARX FOXG1	1.44e-03	56	82	3	GO:0021795
GeneOntologyBiologicalProcess	cell fate specification	NFIB GLI2 PTCH1 TBX1	1.47e-03	123	82	4	GO:0001708
GeneOntologyBiologicalProcess	ventral spinal cord development	FOXN4 GLI2 PTCH1	1.52e-03	57	82	3	GO:0021517
GeneOntologyBiologicalProcess	regulation of type B pancreatic cell apoptotic process	TCF7L2 NEUROD1	1.59e-03	15	82	2	GO:2000674
GeneOntologyBiologicalProcess	mesenchymal cell proliferation	NFIB TBX1 FOXF1	1.68e-03	59	82	3	GO:0010463
GeneOntologyBiologicalProcess	inner ear morphogenesis	GLI2 TRIOBP FOXG1 TBX1	1.75e-03	129	82	4	GO:0042472
GeneOntologyBiologicalProcess	axonogenesis	PRTG PRDM8 NFIB GLI2 ARX ACTL9 PTCH1 FOXG1	1.84e-03	566	82	8	GO:0007409
GeneOntologyBiologicalProcess	cochlea development	GLI2 CECR2 TBX1	1.85e-03	61	82	3	GO:0090102
GeneOntologyBiologicalProcess	pallium development	NEUROD1 EGFR ARX KCNQ2 FOXG1	1.92e-03	222	82	5	GO:0021543
GeneOntologyBiologicalProcess	cell differentiation in spinal cord	FOXN4 GLI2 PTCH1	2.03e-03	63	82	3	GO:0021515
GeneOntologyBiologicalProcess	negative regulation of programmed cell death	TCF7 TCF7L2 NEUROD1 DPP9 EGFR CD27 SH3RF2 GLI2 FBXO7 SOX8 TBX1 PROP1	2.21e-03	1171	82	12	GO:0043069
GeneOntologyBiologicalProcess	genitalia morphogenesis	TCF7 TCF7L2	2.29e-03	18	82	2	GO:0035112
GeneOntologyBiologicalProcess	type B pancreatic cell apoptotic process	TCF7L2 NEUROD1	2.29e-03	18	82	2	GO:0097050
GeneOntologyBiologicalProcess	amacrine cell differentiation	NEUROD1 FOXN4	2.29e-03	18	82	2	GO:0035881
GeneOntologyCellularComponent	chromatin	HOXB9 TCF7 TCF7L2 VENTX NEUROD1 HOXC11 FOXN4 NFIB CECR2 ARX ZFHX2 POGZ FOXN3 ACTL9 SOX8 WDR76 PIAS2 FOXG1 TBX1 FOXF1 SMAD1 PROP1	2.77e-08	1480	81	22	GO:0000785
GeneOntologyCellularComponent	transcription regulator complex	HOXB9 TAF8 TCF7 TCF7L2 NEUROD1 SOX8 ARID5A FOXF1 SMAD1 PROP1	1.00e-04	596	81	10	GO:0005667
GeneOntologyCellularComponent	RNA polymerase II transcription regulator complex	HOXB9 TAF8 TCF7 TCF7L2 NEUROD1 SMAD1	6.59e-04	272	81	6	GO:0090575
GeneOntologyCellularComponent	nuclear protein-containing complex	PRDM8 HOXB9 TAF8 TCF7 TCF7L2 THEMIS NEUROD1 POM121 RGPD8 CECR2 INTS15 TEP1 SMAD1 RGPD5	7.69e-04	1377	81	14	GO:0140513
GeneOntologyCellularComponent	beta-catenin-TCF complex	TCF7 TCF7L2	1.13e-03	13	81	2	GO:1990907
MousePheno	lethality during fetal growth through weaning, incomplete penetrance	PRTG NEUROD1 ATN1 DPP9 EGFR FOXN4 SH3RF2 NFIB STRADA GLI2 CECR2 ARX KCNQ2 FRYL POGZ FOXN3 SIK3 PTCH1 TBX1 FOXF1 PROP1	1.68e-08	1124	65	21	MP:0011112
MousePheno	postnatal lethality, incomplete penetrance	PRTG NEUROD1 ATN1 DPP9 EGFR FOXN4 SH3RF2 NFIB STRADA GLI2 ARX KCNQ2 FRYL FOXN3 FOXF1 PROP1	4.58e-08	669	65	16	MP:0011086
MousePheno	postnatal lethality	PRTG NEUROD1 ATN1 DPP9 EGFR FOXN4 SH3RF2 NFIB STRADA GLI2 ARX FBXO7 KCNQ2 FRYL FOXN3 PTCH1 TBX1 FOXF1 SMAD1 PROP1	5.06e-08	1084	65	20	MP:0002082
MousePheno	abnormal basisphenoid bone morphology	PRTG TCF7L2 GLI2 FOXN3 PTCH1 TBX1	2.41e-07	57	65	6	MP:0000106
MousePheno	abnormal respiratory system development	ZSWIM8 NEUROD1 EGFR NFIB GLI2 PTCH1 FOXG1 FOXF1	7.17e-07	160	65	8	MP:0003115
MousePheno	abnormal response to social novelty	SH3RF2 DLGAP4 ARX POGZ CSMD3	3.03e-06	49	65	5	MP:0020395
MousePheno	abnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell morphology	THEMIS FOXN4 CD27 MAP3K14 SIK3	3.70e-06	51	65	5	MP:0008397
MousePheno	abnormal sphenoid bone morphology	PRTG TCF7L2 GLI2 FOXN3 PTCH1 TBX1	5.02e-06	95	65	6	MP:0000104
MousePheno	small lung saccule	ZSWIM8 NFIB GLI2	5.29e-06	8	65	3	MP:0010827
MousePheno	abnormal pulmonary acinus morphology	ZSWIM8 NEUROD1 EGFR NFIB GLI2 KCNQ2 SPAG17 FOXF1 PROP1	6.13e-06	284	65	9	MP:0010911
MousePheno	abnormal pulmonary alveolar system morphology	ZSWIM8 NEUROD1 EGFR NFIB GLI2 KCNQ2 SPAG17 FOXF1 PROP1	8.56e-06	296	65	9	MP:0010899
MousePheno	abnormal lung saccule morphology	ZSWIM8 NFIB GLI2 FOXF1	9.27e-06	29	65	4	MP:0010825
MousePheno	perinatal lethality, complete penetrance	ZSWIM8 TCF7L2 NEUROD1 DPP9 EGFR NFIB GLI2 ARX KCNQ2 SPAG17 FOXG1 TBX1 FOXF1	1.96e-05	712	65	13	MP:0011089
MousePheno	abnormal basicranium morphology	PRTG TCF7L2 GLI2 FOXN3 PTCH1 TBX1	2.22e-05	123	65	6	MP:0010029
MousePheno	abnormal pulmonary alveolus morphology	NEUROD1 EGFR NFIB GLI2 KCNQ2 SPAG17 FOXF1 PROP1	2.26e-05	255	65	8	MP:0002270
MousePheno	respiratory distress	ZSWIM8 EGFR NFIB SPAG17 FOXG1 FOXF1 PROP1	4.32e-05	204	65	7	MP:0001954
MousePheno	perinatal lethality	ZSWIM8 TCF7L2 NEUROD1 DPP9 EGFR NFIB GLI2 CECR2 ARX KCNQ2 SIK3 SPAG17 FOXG1 TBX1 FOXF1 PROP1	4.37e-05	1130	65	16	MP:0002081
MousePheno	abnormal lung development	ZSWIM8 NEUROD1 EGFR NFIB GLI2 FOXF1	4.99e-05	142	65	6	MP:0001176
MousePheno	abnormal respiratory system morphology	ZSWIM8 PRTG TCF7L2 NEUROD1 RGPD8 EGFR NFIB GLI2 KCNQ2 PTCH1 SPAG17 FOXG1 TBX1 FOXF1 PROP1	5.61e-05	1027	65	15	MP:0002132
MousePheno	abnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell number	THEMIS FOXN4 CD27 SIK3	7.71e-05	49	65	4	MP:0012773
MousePheno	abnormal upper incisor morphology	FOXN3 PTCH1 TBX1	8.82e-05	19	65	3	MP:0030137
MousePheno	abnormal forebrain morphology	DLG5 PRDM8 TCF7L2 NEUROD1 EGFR NFIB CECR2 ARX KCNQ2 POGZ PTCH1 SPAG17 CSMD3 FOXG1 PROP1	9.14e-05	1072	65	15	MP:0000783
MousePheno	abnormal hippocampus development	NEUROD1 NFIB ARX	1.03e-04	20	65	3	MP:0000808
MousePheno	respiratory failure	ZSWIM8 EGFR NFIB SPAG17 FOXG1 TBX1	1.15e-04	165	65	6	MP:0001953
MousePheno	abnormal hippocampus CA4 region morphology	NEUROD1 ARX	1.27e-04	4	65	2	MP:0008269
MousePheno	abnormal craniofacial morphology	DLG5 PRTG PRDM8 TCF7L2 DPP9 EGFR FOXN4 NFIB STRADA GLI2 CECR2 FOXN3 SIK3 PTCH1 FOXG1 TBX1 SMAD1	1.27e-04	1372	65	17	MP:0000428
MousePheno	craniofacial phenotype	DLG5 PRTG PRDM8 TCF7L2 DPP9 EGFR FOXN4 NFIB STRADA GLI2 CECR2 FOXN3 SIK3 PTCH1 FOXG1 TBX1 SMAD1	1.27e-04	1372	65	17	MP:0005382
MousePheno	decreased respiration	ZSWIM8 EGFR NFIB SPAG17 FOXG1 TBX1	1.35e-04	170	65	6	MP:0014274
MousePheno	atelectasis	EGFR NFIB KCNQ2 SPAG17 PROP1	1.43e-04	108	65	5	MP:0001177
MousePheno	abnormal craniofacial development	TCF7L2 EGFR NFIB GLI2 FOXN3 PTCH1 FOXG1 TBX1 SMAD1	1.44e-04	425	65	9	MP:0003935
MousePheno	abnormal head morphology	DLG5 PRTG PRDM8 TCF7L2 DPP9 EGFR FOXN4 STRADA GLI2 CECR2 KCNQ2 FOXN3 PTCH1 FOXG1 TBX1	1.49e-04	1120	65	15	MP:0000432
MousePheno	abnormal incisor morphology	STRADA GLI2 FOXN3 PTCH1 TBX1	1.56e-04	110	65	5	MP:0005358
MousePheno	abnormal mandibular ramus morphology	GLI2 PTCH1 TBX1	1.59e-04	23	65	3	MP:0010150
MousePheno	neonatal lethality, complete penetrance	ZSWIM8 TCF7L2 DPP9 NFIB ARX KCNQ2 SPAG17 FOXG1 TBX1 FOXF1	1.64e-04	534	65	10	MP:0011087
MousePheno	abnormal regulatory T cell number	THEMIS FOXN4 CD27 MAP3K14 SIK3	1.92e-04	115	65	5	MP:0004972
MousePheno	dilated kidney collecting duct	DLG5 EGFR FRYL	2.05e-04	25	65	3	MP:0004860
MousePheno	abnormal regulatory T cell morphology	THEMIS FOXN4 CD27 MAP3K14 SIK3	2.09e-04	117	65	5	MP:0004941
MousePheno	abnormal lung epithelium morphology	NEUROD1 EGFR NFIB GLI2 SPAG17	2.17e-04	118	65	5	MP:0006382
MousePheno	decreased regulatory T cell number	THEMIS CD27 MAP3K14 SIK3	2.19e-04	64	65	4	MP:0004974
MousePheno	abnormal parietal bone morphology	GLI2 FOXN3 SIK3 PTCH1	2.19e-04	64	65	4	MP:0000109
MousePheno	abnormal facial morphology	PRTG PRDM8 TCF7L2 DPP9 EGFR FOXN4 STRADA GLI2 CECR2 FOXN3 PTCH1 FOXG1 TBX1	2.39e-04	910	65	13	MP:0003743
MousePheno	abnormal neurocranium morphology	PRTG TCF7L2 GLI2 FOXN3 SIK3 PTCH1 TBX1	2.43e-04	269	65	7	MP:0000074
MousePheno	neonatal lethality	ZSWIM8 TCF7L2 DPP9 NFIB ARX KCNQ2 SIK3 SPAG17 FOXG1 TBX1 FOXF1 PROP1	2.73e-04	799	65	12	MP:0002058
MousePheno	lens dislocation	INTS15 LTBP2	3.16e-04	6	65	2	MP:0031428
MousePheno	abnormal intestinal enteroendocrine cell morphology	TCF7L2 NEUROD1	3.16e-04	6	65	2	MP:0010802
MousePheno	abnormal telencephalon morphology	DLG5 PRDM8 NEUROD1 EGFR NFIB ARX KCNQ2 POGZ PTCH1 SPAG17 CSMD3 FOXG1	3.17e-04	812	65	12	MP:0000787
MousePheno	abnormal cranium morphology	PRTG PRDM8 TCF7L2 EGFR FOXN4 STRADA GLI2 FOXN3 SIK3 PTCH1 FOXG1 TBX1	3.20e-04	813	65	12	MP:0000438
MousePheno	abnormal craniofacial bone morphology	PRTG PRDM8 TCF7L2 EGFR FOXN4 STRADA GLI2 FOXN3 SIK3 PTCH1 FOXG1 TBX1	3.74e-04	827	65	12	MP:0002116
MousePheno	abnormal viscerocranium morphology	PRTG PRDM8 EGFR FOXN4 STRADA GLI2 FOXN3 SIK3 PTCH1 TBX1	3.81e-04	593	65	10	MP:0005274
MousePheno	abnormal digestive system morphology	PRTG TCF7 TCF7L2 NEUROD1 DPP9 EGFR NFIB STRADA GLI2 MAP3K14 FOXN3 PTCH1 TBX1 FOXF1 SMAD1	4.26e-04	1233	65	15	MP:0000462
MousePheno	abnormal submandibular gland development	EGFR NFIB	4.40e-04	7	65	2	MP:0013541
MousePheno	neonatal lethality, incomplete penetrance	DPP9 NFIB KCNQ2 SIK3 TBX1 FOXF1 PROP1	4.51e-04	298	65	7	MP:0011088
MousePheno	abnormal somatosensory cortex morphology	ARX KCNQ2 POGZ	4.74e-04	33	65	3	MP:0000859
MousePheno	abnormal exocrine gland morphology	PRDM8 TCF7 TCF7L2 NEUROD1 EGFR CD27 NFIB MAP3K14 ARX EXTL3 PTCH1 SMAD1	4.95e-04	853	65	12	MP:0013558
MousePheno	abnormal breathing pattern	ZSWIM8 EGFR NFIB SPAG17 FOXG1 FOXF1 PROP1	4.98e-04	303	65	7	MP:0001951
MousePheno	abnormal respiratory function	ZSWIM8 PRDM8 EGFR NFIB SPAG17 FOXG1 FOXF1 PROP1	5.00e-04	399	65	8	MP:0002327
MousePheno	perinatal lethality, incomplete penetrance	DPP9 EGFR NFIB CECR2 KCNQ2 SIK3 TBX1 FOXF1 PROP1	5.00e-04	503	65	9	MP:0011090
MousePheno	abnormal pulmonary alveolus epithelium morphology	EGFR NFIB GLI2 SPAG17	5.17e-04	80	65	4	MP:0010898
MousePheno	abnormal basioccipital bone morphology	GLI2 FOXN3 TBX1	5.18e-04	34	65	3	MP:0000079
MousePheno	decreased CD4-positive, alpha-beta T cell number	TCF7 THEMIS CD27 FBXO7 SIK3 ARID5A	5.41e-04	220	65	6	MP:0008075
MousePheno	lethality during fetal growth through weaning, complete penetrance	ZSWIM8 TCF7L2 NEUROD1 DPP9 EGFR NFIB GLI2 ARX FBXO7 KCNQ2 PTCH1 SPAG17 FOXG1 TBX1 FOXF1	5.78e-04	1269	65	15	MP:0011111
MousePheno	absent third pharyngeal arch	PTCH1 TBX1	5.85e-04	8	65	2	MP:0010642
MousePheno	increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number	THEMIS FOXN4 SIK3	6.14e-04	36	65	3	MP:0010168
MousePheno	cyanosis	ZSWIM8 EGFR NFIB SPAG17 FOXG1 PROP1	6.23e-04	226	65	6	MP:0001575
MousePheno	decreased alpha-beta T cell number	TCF7 THEMIS CD27 FBXO7 NLRP1 SIK3 ARID5A	6.27e-04	315	65	7	MP:0012765
MousePheno	abnormal tooth morphology	PRDM8 FOXN4 STRADA GLI2 FOXN3 PTCH1 TBX1	6.63e-04	318	65	7	MP:0002100
MousePheno	abnormal parietal lobe morphology	ARX KCNQ2 POGZ	6.66e-04	37	65	3	MP:0000794
MousePheno	abnormal dental arch morphology	PRDM8 FOXN4 STRADA GLI2 FOXN3 PTCH1 TBX1	6.76e-04	319	65	7	MP:0030254
MousePheno	abnormal palate morphology	PRTG EGFR STRADA GLI2 FOXN3 PTCH1 TBX1	7.01e-04	321	65	7	MP:0003755
MousePheno	absent upper incisors	GLI2 TBX1	7.50e-04	9	65	2	MP:0004790
MousePheno	abnormal respiratory epithelium morphology	NEUROD1 EGFR NFIB GLI2 SPAG17 FOXG1	7.64e-04	235	65	6	MP:0010942
MousePheno	abnormal nervous system electrophysiology	NEUROD1 SH3RF2 DLGAP4 ARX ZFHX2 KCNQ2 SIK3	8.10e-04	329	65	7	MP:0002272
MousePheno	abnormal alpha-beta T cell number	TCF7 THEMIS FOXN4 CD27 MAP3K14 FBXO7 NLRP1 SIK3 ARID5A	8.54e-04	542	65	9	MP:0012763
MousePheno	abnormal prepulse inhibition	TANC2 PRDM8 FOXN4 CD27 PALM3 TRIOBP KCNQ2 FOXN3 TBX1	8.54e-04	542	65	9	MP:0003088
MousePheno	abnormal CD4-positive, alpha beta T cell morphology	TCF7 THEMIS FOXN4 CD27 MAP3K14 FBXO7 SIK3 ARID5A	9.06e-04	437	65	8	MP:0002432
MousePheno	abnormal response to novelty	TANC2 RALGAPA1 ATN1 SH3RF2 CECR2 DLGAP4 ARX KCNQ2 POGZ CSMD3 TBX1	9.22e-04	787	65	11	MP:0003107
MousePheno	abnormal terminal bronchiole morphology	EGFR NFIB	9.35e-04	10	65	2	MP:0002268
MousePheno	premature death	ATN1 EGFR GLI2 CECR2 MAP3K14 ARX KCNQ2 NLRP1 FRYL PTCH1 SPAG17 FOXF1 PROP1	9.47e-04	1051	65	13	MP:0002083
MousePheno	abnormal mouth morphology	PRTG PRDM8 DPP9 EGFR FOXN4 STRADA GLI2 FOXN3 PTCH1 TBX1	9.83e-04	670	65	10	MP:0000452
MousePheno	impaired lung alveolus development	NEUROD1 EGFR FOXF1	1.11e-03	44	65	3	MP:0006027
MousePheno	abnormal social investigation	SH3RF2 DLGAP4 ARX POGZ CSMD3	1.18e-03	171	65	5	MP:0001360
MousePheno	abnormal oxygen level	ZSWIM8 EGFR NFIB SPAG17 FOXG1 PROP1	1.19e-03	256	65	6	MP:0001574
MousePheno	decreased vocalization	SH3RF2 DLGAP4 TBX1	1.26e-03	46	65	3	MP:0020351
MousePheno	absent gastric milk in neonates	PRTG TCF7L2 DPP9 SPAG17	1.29e-03	102	65	4	MP:0009546
MousePheno	abnormal mandible morphology	EGFR GLI2 FOXN3 PTCH1 TBX1	1.34e-03	176	65	5	MP:0000458
MousePheno	absent hippocampal commissure	PRDM8 ARX	1.36e-03	12	65	2	MP:0008223
MousePheno	abnormal lens topology	INTS15 LTBP2	1.36e-03	12	65	2	MP:0020486
MousePheno	absent eyelids	EGFR CECR2	1.36e-03	12	65	2	MP:0001341
MousePheno	abnormal pancreatic delta cell number	NEUROD1 ARX	1.36e-03	12	65	2	MP:0020579
MousePheno	microphthalmia	DLG5 EGFR INTS15 NLRP1 FOXN3 EXTL3 TBX1	1.41e-03	362	65	7	MP:0001297
MousePheno	absent presphenoid bone	GLI2 PTCH1	1.61e-03	13	65	2	MP:0004449
MousePheno	abnormal nasal placode morphology	PTCH1 FOXG1	1.61e-03	13	65	2	MP:0006292
MousePheno	small second pharyngeal arch	PTCH1 TBX1	1.61e-03	13	65	2	MP:0006344
MousePheno	abnormal lung alveolus development	NEUROD1 EGFR FOXF1	1.61e-03	50	65	3	MP:0010995
MousePheno	abnormal nervous system development	DLG5 PRDM8 NEUROD1 EGFR NFIB GLI2 CECR2 ARX PTCH1 SPAG17 CSMD3 FOXG1 TBX1 SMAD1	1.62e-03	1257	65	14	MP:0003861
MousePheno	abnormal respiration	ZSWIM8 PRDM8 EGFR NFIB SPAG17 FOXG1 TBX1 FOXF1 PROP1	1.70e-03	598	65	9	MP:0001943
MousePheno	abnormal hippocampus region morphology	NEUROD1 NFIB ARX	1.70e-03	51	65	3	MP:0008262
MousePheno	abnormal neuron differentiation	DLG5 PRDM8 GLI2 PTCH1 FOXG1 TBX1	1.71e-03	275	65	6	MP:0009937
MousePheno	abnormal cerebral hemisphere morphology	PRDM8 NEUROD1 EGFR NFIB ARX KCNQ2 POGZ CSMD3 FOXG1	1.72e-03	599	65	9	MP:0008540
MousePheno	abnormal brain size	DLG5 EGFR STRADA ARX POGZ CSMD3 FOXG1	1.73e-03	375	65	7	MP:0000771
Domain	TF_fork_head_CS_2	FOXN4 FOXN3 FOXG1 FOXF1	4.44e-05	46	80	4	IPR030456
Domain	TF_fork_head_CS_1	FOXN4 FOXN3 FOXG1 FOXF1	4.84e-05	47	80	4	IPR018122
Domain	FH	FOXN4 FOXN3 FOXG1 FOXF1	5.71e-05	49	80	4	SM00339
Domain	FORK_HEAD_1	FOXN4 FOXN3 FOXG1 FOXF1	5.71e-05	49	80	4	PS00657
Domain	FORK_HEAD_2	FOXN4 FOXN3 FOXG1 FOXF1	5.71e-05	49	80	4	PS00658
Domain	Fork_head_dom	FOXN4 FOXN3 FOXG1 FOXF1	5.71e-05	49	80	4	IPR001766
Domain	FORK_HEAD_3	FOXN4 FOXN3 FOXG1 FOXF1	5.71e-05	49	80	4	PS50039
Domain	Forkhead	FOXN4 FOXN3 FOXG1 FOXF1	5.71e-05	49	80	4	PF00250
Domain	CTNNB1-bd_N	TCF7 TCF7L2	1.08e-04	4	80	2	IPR013558
Domain	CTNNB1_binding	TCF7 TCF7L2	1.08e-04	4	80	2	PF08347
Domain	TCF/LEF	TCF7 TCF7L2	1.08e-04	4	80	2	IPR024940
Domain	Homeobox_CS	HOXB9 VENTX HOXC11 ARX ZFHX2 PROP1	1.47e-04	186	80	6	IPR017970
Domain	-	HOXB9 VENTX HOXC11 ARX ZFHX2 POGZ PROP1	2.10e-04	283	80	7	1.10.10.60
Domain	Homeobox	HOXB9 VENTX HOXC11 ARX ZFHX2 PROP1	5.03e-04	234	80	6	PF00046
Domain	HOMEOBOX_1	HOXB9 VENTX HOXC11 ARX ZFHX2 PROP1	5.26e-04	236	80	6	PS00027
Domain	HOX	HOXB9 VENTX HOXC11 ARX ZFHX2 PROP1	5.38e-04	237	80	6	SM00389
Domain	Homeodomain-like	HOXB9 VENTX HOXC11 ARX ZFHX2 POGZ PROP1	5.51e-04	332	80	7	IPR009057
Domain	HOMEOBOX_2	HOXB9 VENTX HOXC11 ARX ZFHX2 PROP1	5.62e-04	239	80	6	PS50071
Domain	Homeobox_dom	HOXB9 VENTX HOXC11 ARX ZFHX2 PROP1	5.62e-04	239	80	6	IPR001356
Domain	Grip	RGPD8 RGPD5	9.72e-04	11	80	2	SM00755
Domain	GRIP	RGPD8 RGPD5	9.72e-04	11	80	2	PF01465
Domain	Ran_BP1	RGPD8 RGPD5	1.16e-03	12	80	2	PF00638
Domain	MAD_homology1_Dwarfin-type	NFIB SMAD1	1.16e-03	12	80	2	IPR003619
Domain	GRIP_dom	RGPD8 RGPD5	1.16e-03	12	80	2	IPR000237
Domain	DWA	NFIB SMAD1	1.16e-03	12	80	2	SM00523
Domain	GRIP	RGPD8 RGPD5	1.16e-03	12	80	2	PS50913
Domain	RANBD1	RGPD8 RGPD5	1.16e-03	12	80	2	PS50196
Domain	MH1	NFIB SMAD1	1.16e-03	12	80	2	PF03165
Domain	RanBD	RGPD8 RGPD5	1.37e-03	13	80	2	SM00160
Domain	Ran_bind_dom	RGPD8 RGPD5	1.37e-03	13	80	2	IPR000156
Domain	HMG_box	TCF7 TCF7L2 SOX8	1.52e-03	53	80	3	PF00505
Domain	HMG_BOX_2	TCF7 TCF7L2 SOX8	1.60e-03	54	80	3	PS50118
Domain	HMG	TCF7 TCF7L2 SOX8	1.60e-03	54	80	3	SM00398
Domain	-	TCF7 TCF7L2 SOX8	1.69e-03	55	80	3	1.10.30.10
Domain	AT_hook	CECR2 DOT1L	2.09e-03	16	80	2	PF02178
Domain	HMG_box_dom	TCF7 TCF7L2 SOX8	2.73e-03	65	80	3	IPR009071
Domain	HTH_motif	HOXB9 ARX PROP1	3.24e-03	69	80	3	IPR000047
Domain	NACHT	NLRP1 TEP1	4.32e-03	23	80	2	PS50837
Domain	NACHT_NTPase	NLRP1 TEP1	4.32e-03	23	80	2	IPR007111
Domain	ZnF_U1	ZFHX2 ZNF318	6.82e-03	29	80	2	SM00451
Domain	Znf_U1	ZFHX2 ZNF318	6.82e-03	29	80	2	IPR003604
Domain	Catenin_binding_dom	TCF7 TCF7L2	6.82e-03	29	80	2	IPR027397
Domain	-	TCF7 TCF7L2	6.82e-03	29	80	2	4.10.900.10
Domain	Znf_C2H2-like	CBLL1 PRDM8 ZNF469 CBLL2 GLI2 ZFHX2 ZNF318 POGZ GPATCH8	6.88e-03	796	80	9	IPR015880
Domain	ZnF_C2H2	CBLL1 PRDM8 ZNF469 CBLL2 GLI2 ZFHX2 ZNF318 POGZ GPATCH8	7.56e-03	808	80	9	SM00355
Domain	CARD	DLG5 NLRP1	7.77e-03	31	80	2	IPR001315
Domain	HMGI/Y_DNA-bd_CS	CECR2 DOT1L	7.77e-03	31	80	2	IPR000637
Pathway	KEGG_BASAL_CELL_CARCINOMA	TCF7 TCF7L2 GLI2 PTCH1	7.52e-05	55	58	4	M17807
Pathway	REACTOME_RUNX3_REGULATES_WNT_SIGNALING	TCF7 TCF7L2	2.47e-04	6	58	2	MM15542
Pathway	KEGG_MEDICUS_PATHOGEN_SALMONELLA_AVRA_TO_BETA_CATENIN_SIGNALING_PATHWAY	TCF7 TCF7L2	2.47e-04	6	58	2	M47736
Pathway	REACTOME_GLI_PROTEINS_BIND_PROMOTERS_OF_HH_RESPONSIVE_GENES_TO_PROMOTE_TRANSCRIPTION	GLI2 PTCH1	3.45e-04	7	58	2	M27501
Pathway	KEGG_MEDICUS_PATHOGEN_KSHV_LANA_TO_WNT_SIGNALING_PATHWAY	TCF7 TCF7L2	3.45e-04	7	58	2	M47465
Pathway	REACTOME_REGULATION_OF_MITF_M_DEPENDENT_GENES_INVOLVED_IN_CELL_CYCLE_AND_PROLIFERATION	TCF7 TCF7L2	4.58e-04	8	58	2	MM17229
Pathway	REACTOME_BINDING_OF_TCF_LEF_CTNNB1_TO_TARGET_GENE_PROMOTERS	TCF7 TCF7L2	4.58e-04	8	58	2	M27359
Pathway	KEGG_MEDICUS_VARIANT_CDH1_REDUCED_EXPRESSION_TO_BETA_CATENIN_SIGNALING_PATHWAY	TCF7 TCF7L2	4.58e-04	8	58	2	M47413
Pathway	REACTOME_RUNX3_REGULATES_WNT_SIGNALING	TCF7 TCF7L2	4.58e-04	8	58	2	M27821
Pubmed	A census of human transcription factors: function, expression and evolution.	HOXB9 TCF7 TCF7L2 VENTX NEUROD1 HOXC11 FOXN4 NFIB GLI2 ARX ZFHX2 FOXN3 SOX8 FOXG1 TBX1 FOXF1 SMAD1 PROP1	3.28e-12	908	82	18	19274049
Pubmed	Human transcription factor protein interaction networks.	MRPL4 HOXB9 TAF8 TCF7 TCF7L2 HOXC11 ATN1 GSE1 NFIB GLI2 FBRSL1 RPRD2 ZNF318 POGZ GPATCH8 DOT1L ANKHD1 PIAS2	4.82e-09	1429	82	18	35140242
Pubmed	Impact of cytosine methylation on DNA binding specificities of human transcription factors.	HOXB9 TCF7 VENTX NEUROD1 HOXC11 NFIB GLI2 ARX SOX8 FOXG1 TBX1 PROP1	5.83e-09	544	82	12	28473536
Pubmed	Protein interactome reveals converging molecular pathways among autism disorders.	ZSWIM8 ATN1 RGPD8 CEP72 DLGAP4 ARX FBXO7 TRIOBP RPRD2 FRYL COIL	8.54e-08	560	82	11	21653829
Pubmed	TCF4 deficiency expands ventral diencephalon signaling and increases induction of pituitary progenitors.	TCF7 TCF7L2 SMAD1 PROP1	2.03e-07	22	82	4	17919533
Pubmed	Hedgehog-GLI signaling regulates the behavior of cells with stem cell properties in the developing neocortex.	NEUROD1 EGFR GLI2	2.51e-07	6	82	3	14681189
Pubmed	Conditional and constitutive expression of a Tbx1-GFP fusion protein in mice.	NEUROD1 FOXG1 TBX1	2.51e-07	6	82	3	23971992
Pubmed	Lef1 is required for the transition of Wnt signaling from mesenchymal to epithelial cells in the mouse embryonic mammary gland.	TCF7 GLI2 PTCH1	4.39e-07	7	82	3	16678815
Pubmed	Forkhead box F2 regulation of platelet-derived growth factor and myocardin/serum response factor signaling is essential for intestinal development.	EGFR GLI2 PTCH1 FOXF1	4.83e-07	27	82	4	25631042
Pubmed	A Retinoic Acid-Hedgehog Cascade Coordinates Mesoderm-Inducing Signals and Endoderm Competence during Lung Specification.	GLI2 PTCH1 FOXF1 SMAD1	6.52e-07	29	82	4	27320915
Pubmed	GLI transcriptional repression is inert prior to Hedgehog pathway activation.	GLI2 PTCH1 FOXF1	7.01e-07	8	82	3	35145123
Pubmed	pRb-mediated control of epithelial cell proliferation and Indian hedgehog expression in mouse intestinal development.	TCF7L2 NEUROD1 GLI2 PTCH1	7.51e-07	30	82	4	17257418
Pubmed	Distinct Sonic Hedgehog signaling dynamics specify floor plate and ventral neuronal progenitors in the vertebrate neural tube.	GLI2 ARX PTCH1	1.05e-06	9	82	3	20516201
Pubmed	Patched1 patterns Fibroblast growth factor 10 and Forkhead box F1 expression during pulmonary branch formation.	GLI2 PTCH1 FOXF1	1.50e-06	10	82	3	28939119
Pubmed	Fusion of lung lobes and vessels in mouse embryos heterozygous for the forkhead box f1 targeted allele.	GLI2 PTCH1 FOXF1	1.50e-06	10	82	3	11943666
Pubmed	Interaction network of human early embryonic transcription factors.	HOXB9 TCF7L2 ATN1 GSE1 NFIB FBRSL1 POGZ PIAS2	1.85e-06	351	82	8	38297188
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	RALGAPA1 TCF7L2 DPP9 EGFR ERV3-1 NFIB GLI2 FBRSL1 TRIOBP ZFHX2 RPRD2 FRYL FOXN3 BCAR1 TEP1	1.86e-06	1489	82	15	28611215
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	TANC2 ZSWIM8 ZNF469 TAF8 ATN1 GSE1 CECR2 FBRSL1 ZNF318 POGZ SIK3 ANKHD1 TEP1	2.05e-06	1116	82	13	31753913
Pubmed	CPLANE protein INTU regulates growth and patterning of the mouse lungs through cilia-dependent Hh signaling.	GLI2 PTCH1 FOXF1	2.06e-06	11	82	3	39029571
Pubmed	Hippocampus development and generation of dentate gyrus granule cells is regulated by LEF1.	TCF7 TCF7L2 FOXG1	2.74e-06	12	82	3	10631168
Pubmed	CTCF Regulates Otic Neurogenesis via Histone Modification in the Neurog1 Locus.	NEUROD1 FOXG1 TBX1	2.74e-06	12	82	3	30008200
Pubmed	The ATP-dependent chromatin remodeling enzyme CHD7 regulates pro-neural gene expression and neurogenesis in the inner ear.	NEUROD1 FOXG1 TBX1	2.74e-06	12	82	3	20736290
Pubmed	High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men.	TCF7 EGFR GLI2 MAP3K14 LTBP2 PTCH1 SMAD1 PROP1	3.52e-06	383	82	8	19453261
Pubmed	Excess NF-κB induces ectopic odontogenesis in embryonic incisor epithelium.	MAP3K14 PTCH1 SMAD1	3.55e-06	13	82	3	25376721
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	RALGAPA1 DLG5 CECR2 FBRSL1 TRIOBP RPRD2 POGZ SIK3 ANKHD1	4.46e-06	529	82	9	14621295
Pubmed	Lrp4 modulates extracellular integration of cell signaling pathways in development.	GLI2 PTCH1 SMAD1	4.51e-06	14	82	3	19116665
Pubmed	Primary Cilia are Required for Cell-Type Determination and Angiogenesis in Pituitary Development.	GLI2 PTCH1 FOXF1 PROP1	4.74e-06	47	82	4	39001875
Pubmed	Erk and MAPK signaling is essential for intestinal development through Wnt pathway modulation.	EGFR GLI2 PTCH1 SMAD1	4.74e-06	47	82	4	32747435
Pubmed	Ptch1 and Gli regulate Shh signalling dynamics via multiple mechanisms.	GLI2 PTCH1	5.49e-06	2	82	2	25833741
Pubmed	Tissue-specific roles of Tbx1 in the development of the outer, middle and inner ear, defective in 22q11DS patients.	FOXG1 TBX1	5.49e-06	2	82	2	16600992
Pubmed	Inflammasome sensor NLRP1 disease variant M1184V promotes autoproteolysis and DPP9 complex formation by stabilizing the FIIND domain.	DPP9 NLRP1	5.49e-06	2	82	2	36309085
Pubmed	Gastric cancer (GC) patients with hedgehog pathway activation: PTCH1 and GLI2 as independent prognostic factors.	GLI2 PTCH1	5.49e-06	2	82	2	23371028
Pubmed	Human DPP9 represses NLRP1 inflammasome and protects against autoinflammatory diseases via both peptidase activity and FIIND domain binding.	DPP9 NLRP1	5.49e-06	2	82	2	30291141
Pubmed	Hedgehog signaling, keratin 6 induction, and sebaceous gland morphogenesis: implications for pachyonychia congenita and related conditions.	GLI2 PTCH1	5.49e-06	2	82	2	18688029
Pubmed	Genome-Wide Epigenetic Landscape of Lung Adenocarcinoma Links HOXB9 DNA Methylation to Intrinsic EGFR-TKI Resistance and Heterogeneous Responses.	HOXB9 EGFR	5.49e-06	2	82	2	34036228
Pubmed	Prevention of premature fusion of calvarial suture in GLI-Kruppel family member 3 (Gli3)-deficient mice by removing one allele of Runt-related transcription factor 2 (Runx2).	GLI2 PTCH1 SMAD1	5.63e-06	15	82	3	22547067
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	HOXB9 TCF7 TCF7L2 FOXN4 GLI2 ZFHX2 ZNF318 POGZ FOXN3 FOXG1	6.65e-06	709	82	10	22988430
Pubmed	Spatial and temporal inhibition of FGFR2b ligands reveals continuous requirements and novel targets in mouse inner ear morphogenesis.	NEUROD1 FOXG1 TBX1	6.92e-06	16	82	3	30504125
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	ZNF469 TCF7L2 POM121 ATN1 GLI2 BCAR1 PTCH1 SMAD1	8.20e-06	430	82	8	35044719
Pubmed	A sonic hedgehog-dependent signaling relay regulates growth of diencephalic and mesencephalic primordia in the early mouse embryo.	TCF7L2 PTCH1 FOXG1	8.39e-06	17	82	3	12361972
Pubmed	Stage-specific regulation of oligodendrocyte development by Wnt/β-catenin signaling.	TCF7L2 GLI2 PTCH1	8.39e-06	17	82	3	24948802
Pubmed	Tbx2 and Tbx3 Act Downstream of Shh to Maintain Canonical Wnt Signaling during Branching Morphogenesis of the Murine Lung.	PTCH1 FOXG1 SMAD1	1.00e-05	18	82	3	27720610
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	ZSWIM8 DLG5 GSE1 RGPD8 FBRSL1 ZNF318 BCAR1 DOT1L PIAS2	1.04e-05	588	82	9	38580884
Pubmed	Otic ablation of smoothened reveals direct and indirect requirements for Hedgehog signaling in inner ear development.	PTCH1 FOXG1 TBX1	1.19e-05	19	82	3	21831920
Pubmed	SP8 regulates signaling centers during craniofacial development.	GLI2 PTCH1 FOXG1	1.19e-05	19	82	3	23872235
Pubmed	Multiple roles for HOXA3 in regulating thymus and parathyroid differentiation and morphogenesis in mouse.	PTCH1 FOXG1 TBX1	1.19e-05	19	82	3	25249461
Pubmed	The ciliary G-protein-coupled receptor Gpr161 negatively regulates the Sonic hedgehog pathway via cAMP signaling.	GLI2 PTCH1 FOXG1	1.19e-05	19	82	3	23332756
Pubmed	A Shh/Gli-driven three-node timer motif controls temporal identity and fate of neural stem cells.	GLI2 ARX PTCH1	1.19e-05	19	82	3	32938678
Pubmed	Fuz regulates craniofacial development through tissue specific responses to signaling factors.	TCF7L2 GLI2 PTCH1	1.40e-05	20	82	3	21935430
Pubmed	Sequential roles of Hedgehog and Wnt signaling in osteoblast development.	TCF7 TCF7L2 PTCH1	1.40e-05	20	82	3	15576404
Pubmed	Receptor tyrosine kinase-like orphan receptor 2 (ROR2) and Indian hedgehog regulate digit outgrowth mediated by the phalanx-forming region.	TCF7L2 PTCH1 SMAD1	1.40e-05	20	82	3	20660756
Pubmed	Pinin modulates expression of an intestinal homeobox gene, Cdx2, and plays an essential role for small intestinal morphogenesis.	TCF7L2 GLI2 PTCH1	1.40e-05	20	82	3	20637749
Pubmed	Function of Wnt/β-catenin in counteracting Tcf3 repression through the Tcf3-β-catenin interaction.	TCF7 TCF7L2 PTCH1	1.40e-05	20	82	3	22573616
Pubmed	Sox9 is required for invagination of the otic placode in mice.	NEUROD1 SOX8 FOXG1	1.40e-05	20	82	3	18377888
Pubmed	Single cell transcriptomics identifies a signaling network coordinating endoderm and mesoderm diversification during foregut organogenesis.	GLI2 FOXF1 SMAD1	1.63e-05	21	82	3	32855417
Pubmed	VGLL1 stabilization of cytoplasmic TAZ promotes EGFR expression and maintains tumor initiating cells in breast cancer independent of TEAD.	EGFR VGLL1	1.64e-05	3	82	2	38417636
Pubmed	Smad1, beta-catenin and Tcf4 associate in a molecular complex with the Myc promoter in dysplastic renal tissue and cooperate to control Myc transcription.	TCF7L2 SMAD1	1.64e-05	3	82	2	15576399
Pubmed	Hhip regulates tumor-stroma-mediated upregulation of tumor angiogenesis.	GLI2 PTCH1	1.64e-05	3	82	2	28127049
Pubmed	EGFR Mutation Promotes Glioblastoma through Epigenome and Transcription Factor Network Remodeling.	EGFR FOXG1	1.64e-05	3	82	2	26455392
Pubmed	The role of sonic hedgehog homologue signal pathway in hypospadias aetiology.	GLI2 PTCH1	1.64e-05	3	82	2	34275739
Pubmed	Loss of FOXN3 in colon cancer activates beta-catenin/TCF signaling and promotes the growth and migration of cancer cells.	TCF7L2 FOXN3	1.64e-05	3	82	2	28039460
Pubmed	Structural and biochemical mechanisms of NLRP1 inhibition by DPP9.	DPP9 NLRP1	1.64e-05	3	82	2	33731929
Pubmed	DPP9 sequesters the C terminus of NLRP1 to repress inflammasome activation.	DPP9 NLRP1	1.64e-05	3	82	2	33731932
Pubmed	Structural basis of plasticity in protein tyrosine phosphatase 1B substrate recognition.	EGFR BCAR1	1.64e-05	3	82	2	10889023
Pubmed	DPP9 restrains NLRP1 activation.	DPP9 NLRP1	1.64e-05	3	82	2	33785922
Pubmed	The epidermal growth factor receptor engages receptor interacting protein and nuclear factor-kappa B (NF-kappa B)-inducing kinase to activate NF-kappa B. Identification of a novel receptor-tyrosine kinase signalosome.	EGFR MAP3K14	1.64e-05	3	82	2	11116146
Pubmed	NeuroD1 Dictates Tumor Cell Differentiation in Medulloblastoma.	NEUROD1 PTCH1	1.64e-05	3	82	2	32579914
Pubmed	Gli1 is important for medulloblastoma formation in Ptc1+/- mice.	GLI2 PTCH1	1.64e-05	3	82	2	15806168
Pubmed	TBX1 and Basal Cell Carcinoma: Expression and Interactions with Gli2 and Dvl2 Signaling.	GLI2 TBX1	1.64e-05	3	82	2	31963474
Pubmed	Disrupting Interactions Between β-Catenin and Activating TCFs Reconstitutes Ground State Pluripotency in Mouse Embryonic Stem Cells.	TCF7 TCF7L2	1.64e-05	3	82	2	28577307
Pubmed	Human brain factor 1, a new member of the fork head gene family.	FOXG1 FOXF1	1.64e-05	3	82	2	7959731
Pubmed	Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci.	GLI2 LTBP2 EXTL3 PTCH1 SPAG17	1.82e-05	136	82	5	25429064
Pubmed	Specification of the mammalian cochlea is dependent on Sonic hedgehog.	NEUROD1 PTCH1 TBX1	1.88e-05	22	82	3	12231626
Pubmed	NDST1-dependent heparan sulfate regulates BMP signaling and internalization in lung development.	PTCH1 TBX1 SMAD1	1.88e-05	22	82	3	19299468
Pubmed	Hedgehog signaling patterns the oral-aboral axis of the mandibular arch.	PTCH1 FOXF1 SMAD1	1.88e-05	22	82	3	30638444
Pubmed	Neural crest cells require Meis2 for patterning the mandibular arch via the Sonic hedgehog pathway.	PTCH1 FOXF1 SMAD1	2.16e-05	23	82	3	32616504
Pubmed	Dosage-dependent hedgehog signals integrated with Wnt/beta-catenin signaling regulate external genitalia formation as an appendicular program.	TCF7 GLI2 PTCH1	2.16e-05	23	82	3	19906864
Pubmed	Dual mechanism underlying failure of neural tube closure in the Zic2 mutant mouse.	GLI2 PTCH1 SMAD1	2.47e-05	24	82	3	36916392
Pubmed	Dentate gyrus morphogenesis is regulated by β-catenin function in hem-derived fimbrial glia.	TCF7L2 NEUROD1 NFIB	2.80e-05	25	82	3	36196585
Pubmed	Wnt signaling determines ventral spinal cord cell fates in a time-dependent manner.	GLI2 PTCH1 SMAD1	2.80e-05	25	82	3	18927156
Pubmed	The Wnt effector transcription factor 7-like 2 positively regulates oligodendrocyte differentiation in a manner independent of Wnt/β-catenin signaling.	TCF7 TCF7L2 SMAD1	3.16e-05	26	82	3	25810530
Pubmed	Type 1 fibroblast growth factor receptor in cranial neural crest cell-derived mesenchyme is required for palatogenesis.	GLI2 PTCH1 SMAD1	3.16e-05	26	82	3	23754280
Pubmed	The prognostic significance and therapeutic potential of hedgehog signaling in intrahepatic cholangiocellular carcinoma.	GLI2 PTCH1	3.28e-05	4	82	2	23493353
Pubmed	Hedgehog signaling in neonatal and adult lung.	GLI2 PTCH1	3.28e-05	4	82	2	23371063
Pubmed	SOXE group transcription factors regulates the expression of FoxG1 during inner ear development.	SOX8 FOXG1	3.28e-05	4	82	2	35878429
Pubmed	Epidermal growth factor modulates tyrosine phosphorylation of a novel tensin family member, tensin3.	EGFR BCAR1	3.28e-05	4	82	2	15140944
Pubmed	TCF transcription factors: molecular switches in carcinogenesis.	TCF7 TCF7L2	3.28e-05	4	82	2	10528152
Pubmed	Transient retinoic acid signaling confers anterior-posterior polarity to the inner ear.	NEUROD1 TBX1	3.28e-05	4	82	2	21173260
Pubmed	Inhibition of Dpp8/9 Activates the Nlrp1b Inflammasome.	DPP9 NLRP1	3.28e-05	4	82	2	29396289
Pubmed	Identification of a novel Ran binding protein 2 related gene (RANBP2L1) and detection of a gene cluster on human chromosome 2q11-q12.	RGPD8 RGPD5	3.28e-05	4	82	2	9480752
Pubmed	Mapping canonical Wnt signaling in the developing and adult retina.	TCF7 TCF7L2	3.28e-05	4	82	2	17065530
Pubmed	Hedgehog signaling drives medulloblastoma growth via CDK6.	GLI2 PTCH1	3.28e-05	4	82	2	29202464
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	MRPL4 EGFR NFIB INTS15 RPRD2 ZNF318 SIK3 PIAS2 FOXF1	3.61e-05	689	82	9	36543142
Pubmed	Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus.	HOXB9 TCF7L2 FOXN4 ZFHX2 FOXN3 FOXG1	3.82e-05	263	82	6	20932939
Pubmed	Role of neuroepithelial Sonic hedgehog in hypothalamic patterning.	ARX PTCH1 FOXG1	3.97e-05	28	82	3	19474326
Pubmed	Loss of Sox9 in the periotic mesenchyme affects mesenchymal expansion and differentiation, and epithelial morphogenesis during cochlea development in the mouse.	PTCH1 TBX1 SMAD1	3.97e-05	28	82	3	20346939
Pubmed	Convergent extension movements in growth plate chondrocytes require gpi-anchored cell surface proteins.	PTCH1 FOXG1 SMAD1	3.97e-05	28	82	3	19762422
Pubmed	An atlas of combinatorial transcriptional regulation in mouse and man.	HOXB9 TCF7 VENTX NEUROD1 HOXC11 SOX8 PIAS2 VGLL1 FOXG1 SMAD1	4.10e-05	877	82	10	20211142
Pubmed	Direct and indirect requirements of Shh/Gli signaling in early pituitary development.	GLI2 FOXG1 PROP1	4.42e-05	29	82	3	20934421
Pubmed	Distinct effects of Hedgehog signaling on neuronal fate specification and cell cycle progression in the embryonic mouse retina.	NEUROD1 GLI2 PTCH1	4.42e-05	29	82	3	19474320
Interaction	TLE3 interactions	CBLL1 TCF7L2 VENTX POM121 ATN1 GSE1 NFIB GLI2 CECR2 FBXO7 FBRSL1 ZNF318 GPATCH8 DOT1L FOXG1	2.33e-11	376	81	15	int:TLE3
Interaction	FAM168B interactions	HOXB9 TCF7L2 VENTX POM121 POGZ ARID5A	1.20e-07	58	81	6	int:FAM168B
Interaction	FEV interactions	HOXB9 TAF8 TCF7L2 GSE1 NFIB FBRSL1 POGZ GPATCH8 PIAS2	1.25e-07	203	81	9	int:FEV
Interaction	SP7 interactions	TCF7L2 ATN1 GSE1 NFIB FBRSL1 RPRD2 ZNF318 POGZ GPATCH8 PIAS2	3.84e-07	304	81	10	int:SP7
Interaction	TBXT interactions	TCF7L2 ATN1 GSE1 NFIB FBRSL1 POGZ DOT1L	4.27e-07	116	81	7	int:TBXT
Interaction	TEAD1 interactions	HOXB9 TCF7L2 GSE1 EGFR NFIB FBRSL1 PIAS2 VGLL1	5.39e-07	176	81	8	int:TEAD1
Interaction	RBPMS interactions	HOXB9 TCF7L2 VENTX POM121 ATN1 GSE1 SH3RF2 POGZ ANKHD1 ARID5A	1.06e-06	340	81	10	int:RBPMS
Interaction	NFIC interactions	TCF7L2 GSE1 NFIB FBXO7 FBRSL1 POGZ DOT1L COIL	2.04e-06	210	81	8	int:NFIC
Interaction	SOX5 interactions	GSE1 RGPD8 NFIB POGZ PIAS2 ARID5A SMAD1	4.02e-06	162	81	7	int:SOX5
Interaction	TLX1 interactions	HOXB9 TCF7L2 ATN1 GSE1 NFIB FBRSL1 POGZ	6.69e-06	175	81	7	int:TLX1
Interaction	ACTMAP interactions	TCF7L2 VENTX POGZ ARID5A PROP1	1.28e-05	75	81	5	int:ACTMAP
Interaction	TRIP6 interactions	HOXB9 POM121 ATN1 GSE1 EGFR CECR2 SIK3 BCAR1 SMAD1	1.35e-05	358	81	9	int:TRIP6
Interaction	EEF1AKMT2 interactions	GSE1 RGPD8 FBXO7 ZNF318	2.65e-05	43	81	4	int:EEF1AKMT2
Interaction	PRR20B interactions	TCF7L2 VENTX POGZ ANKHD1 ARID5A	3.11e-05	90	81	5	int:PRR20B
Interaction	PRR20C interactions	TCF7L2 VENTX POGZ ANKHD1 ARID5A	3.11e-05	90	81	5	int:PRR20C
Interaction	PRR20D interactions	TCF7L2 VENTX POGZ ANKHD1 ARID5A	3.11e-05	90	81	5	int:PRR20D
Interaction	ATXN1L interactions	ZSWIM8 NFIB GPATCH8 COIL ANKHD1 ARID5A	3.15e-05	150	81	6	int:ATXN1L
Interaction	ODAM interactions	VENTX POGZ ARID5A	3.37e-05	16	81	3	int:ODAM
Interaction	POLR1C interactions	NOP9 HOXB9 EGFR MAP3K14 TRIOBP RPRD2 DOT1L WDR76	3.56e-05	311	81	8	int:POLR1C
Interaction	AR interactions	TAF8 TCF7L2 ATN1 GSE1 EGFR NFIB GLI2 RPRD2 ZNF318 DOT1L PIAS2 ARID5A FOXG1 SMAD1	3.74e-05	992	81	14	int:AR
Interaction	NUP43 interactions	POM121 ATN1 GSE1 RGPD8 EGFR ZNF318 POGZ GPATCH8 COIL CSMD3 RGPD5	3.95e-05	625	81	11	int:NUP43
Interaction	SMUG1 interactions	TCF7L2 VENTX ZNF318 PROP1	4.12e-05	48	81	4	int:SMUG1
Interaction	SMG7 interactions	ZSWIM8 GSE1 EGFR RPRD2 ZNF318 GPATCH8 DOT1L COIL	4.26e-05	319	81	8	int:SMG7
Interaction	NPIPB6 interactions	RGPD8 EGFR RGPD5	4.89e-05	18	81	3	int:NPIPB6
Interaction	KRTAP19-5 interactions	HOXB9 TCF7L2 ATN1 ANKHD1 ARID5A	4.93e-05	99	81	5	int:KRTAP19-5
Interaction	PRR20E interactions	TCF7L2 VENTX POGZ ANKHD1 ARID5A	5.42e-05	101	81	5	int:PRR20E
Interaction	EGR2 interactions	TCF7L2 ATN1 FBRSL1 POGZ SOX8 PIAS2	6.55e-05	171	81	6	int:EGR2
Interaction	PRR20A interactions	TCF7L2 VENTX POGZ ANKHD1 ARID5A	7.80e-05	109	81	5	int:PRR20A
Interaction	TIMM13 interactions	TCF7L2 EGFR STRADA MAP3K14 GPATCH8 WDR76	7.93e-05	177	81	6	int:TIMM13
Interaction	TAF1 interactions	TAF8 ATN1 GSE1 FBRSL1 WDR76 COIL SMAD1	8.46e-05	260	81	7	int:TAF1
Interaction	PAX8 interactions	HOXB9 GSE1 FBXO3 NFIB FBRSL1	8.50e-05	111	81	5	int:PAX8
Interaction	TIMM8B interactions	TCF7L2 STRADA MAP3K14 GPATCH8	9.95e-05	60	81	4	int:TIMM8B
Interaction	DAZAP2 interactions	TCF7 TCF7L2 VENTX POGZ ARID5A PROP1	1.04e-04	186	81	6	int:DAZAP2
Interaction	KRTAP6-2 interactions	HOXB9 TCF7L2 VENTX ATN1 POGZ ARID5A	1.07e-04	187	81	6	int:KRTAP6-2
Interaction	NFIA interactions	HOXB9 TCF7L2 GSE1 NFIB FBXO7 COIL	1.11e-04	188	81	6	int:NFIA
Interaction	TSC1 interactions	TCF7L2 VENTX ATN1 EGFR TRIOBP POGZ ARID5A FOXG1	1.11e-04	366	81	8	int:TSC1
Interaction	HOXC13 interactions	EGFR COIL FOXG1	1.19e-04	24	81	3	int:HOXC13
Interaction	TEKT4 interactions	GSE1 EGFR ARID5A VGLL1 PROP1	1.28e-04	121	81	5	int:TEKT4
Interaction	VSX1 interactions	HOXB9 TCF7 NFIB FBRSL1	1.44e-04	66	81	4	int:VSX1
Interaction	CSMD3 interactions	EGFR CSMD3	1.58e-04	5	81	2	int:CSMD3
Interaction	UXT interactions	EGFR CECR2 FBXO7 RPRD2 PIAS2	1.60e-04	127	81	5	int:UXT
Interaction	JPH4 interactions	ZSWIM8 POM121 TRIOBP GPATCH8	1.62e-04	68	81	4	int:JPH4
Interaction	KRTAP12-2 interactions	HOXB9 VENTX ATN1 CBLL2 ARID5A	1.66e-04	128	81	5	int:KRTAP12-2
Interaction	TLX3 interactions	HOXB9 TCF7L2 HOXC11 GSE1 NFIB FBRSL1 POGZ	1.70e-04	291	81	7	int:TLX3
Interaction	LEF1 interactions	TCF7 TCF7L2 SMAD1 PROP1	1.72e-04	69	81	4	int:LEF1
Interaction	PAX9 interactions	ATN1 GSE1 NFIB FBRSL1 PIAS2	1.79e-04	130	81	5	int:PAX9
Interaction	RFX2 interactions	FOXN4 FOXN3 PIAS2	1.91e-04	28	81	3	int:RFX2
Interaction	BAG2 interactions	EGFR MAP3K14 FBXO7 KCNQ2 RPRD2 ZNF318 DOT1L WDR76 ANKHD1 TEP1	1.91e-04	622	81	10	int:BAG2
Interaction	TLE1 interactions	VENTX ATN1 NFIB FOXG1 TBX1 PROP1	2.18e-04	213	81	6	int:TLE1
Interaction	AKIRIN2 interactions	RGPD8 EGFR FBXO7 RGPD5	2.25e-04	74	81	4	int:AKIRIN2
Interaction	SNRNP40 interactions	CBLL1 POM121 ATN1 GSE1 EGFR ZNF318 POGZ GPATCH8 DOT1L COIL	2.31e-04	637	81	10	int:SNRNP40
Interaction	OLIG3 interactions	ATN1 ARID5A PROP1	2.35e-04	30	81	3	int:OLIG3
Interaction	ESRP1 interactions	RGPD8 GPATCH8 ARID5A RGPD5	2.62e-04	77	81	4	int:ESRP1
Interaction	KRTAP8-1 interactions	VENTX POGZ ARID5A PROP1	2.89e-04	79	81	4	int:KRTAP8-1
Interaction	NUP35 interactions	TCF7L2 POM121 ATN1 GSE1 NFIB GPATCH8 BCAR1 ANKHD1	3.02e-04	424	81	8	int:NUP35
Interaction	KLF3 interactions	TCF7L2 GSE1 NFIB FBRSL1 POGZ PIAS2	3.14e-04	228	81	6	int:KLF3
Interaction	KRTAP15-1 interactions	ATN1 EGFR ANKHD1 ARID5A	3.18e-04	81	81	4	int:KRTAP15-1
Interaction	MUC12 interactions	EGFR MUC12	3.31e-04	7	81	2	int:MUC12
Interaction	PRSS42P interactions	EGFR DLGAP4	3.31e-04	7	81	2	int:PRSS42P
Interaction	SOX7 interactions	TCF7L2 NFIB CECR2 DOT1L	3.34e-04	82	81	4	int:SOX7
Interaction	HOXD13 interactions	COIL FOXG1 FOXF1 SMAD1	3.34e-04	82	81	4	int:HOXD13
Interaction	CNOT9 interactions	EGFR CEP72 GLI2 RPRD2 ZNF318 ANKHD1	3.37e-04	231	81	6	int:CNOT9
Interaction	TIMM8A interactions	TCF7L2 STRADA MAP3K14 SIK3	3.50e-04	83	81	4	int:TIMM8A
Interaction	DTX2 interactions	GSE1 EGFR NFIB RPRD2 POGZ PIAS2 ARID5A	3.65e-04	330	81	7	int:DTX2
Interaction	PAX2 interactions	GSE1 NFIB FBRSL1 POGZ	3.83e-04	85	81	4	int:PAX2
Interaction	TAF5 interactions	TAF8 EGFR WDR76 SMAD1	4.00e-04	86	81	4	int:TAF5
Interaction	FBLN5 interactions	POM121 ATN1 FOXG1 FOXF1 SOD3	4.54e-04	159	81	5	int:FBLN5
Interaction	NR2E1 interactions	ATN1 GSE1 RGPD5	4.77e-04	38	81	3	int:NR2E1
Interaction	GTF3C5 interactions	EGFR DOT1L COIL FOXG1 SMAD1	4.80e-04	161	81	5	int:GTF3C5
Interaction	KRTAP6-3 interactions	HOXB9 TCF7L2 VENTX ARID5A PROP1	4.80e-04	161	81	5	int:KRTAP6-3
Interaction	RBFOX1 interactions	VENTX ATN1 POGZ ARID5A	5.17e-04	92	81	4	int:RBFOX1
Interaction	LENG8 interactions	ATN1 GSE1 EGFR ANKHD1 ARID5A	5.23e-04	164	81	5	int:LENG8
GeneFamily	Forkhead boxes	FOXN4 FOXN3 FOXG1 FOXF1	8.04e-06	43	54	4	508
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HRGL2B	TCF7L2 EGFR NFIB KCNQ2 SOX8 PTCH1 SPAG17 CSMD3 PIAS2	9.50e-06	439	82	9	M39054
Coexpression	GSE7568_CTRL_VS_3H_TGFB_TREATED_MACROPHAGES_WITH_IL4_AND_DEXAMETHASONE_DN	MRPL4 TCF7 RPRD2 ZNF318 SIK3 WDR76	1.43e-05	167	82	6	M361
CoexpressionAtlas	FacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#4	ZSWIM8 PRTG CECR2 FOXN3 GPATCH8 SOX8 FOXF1	8.03e-05	275	80	7	Facebase_RNAseq_e9.5_Maxillary Arch_2500_K4
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_500	GSE1 CECR2 ARX FBRSL1 ZFHX2 FRYL SOX8 WDR76 FOXG1	8.26e-05	482	80	9	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_500
CoexpressionAtlas	FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_500	PRTG TCF7L2 CECR2 ST6GALNAC5 MAP3K14 ARX PALM3 ZFHX2 WDR76	1.01e-04	495	80	9	Facebase_RNAseq_e8.5_Floor Plate_500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_500	PRTG TCF7L2 GSE1 CD27 CECR2 ARX ZFHX2 FRYL FOXG1	1.03e-04	496	80	9	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_500
ToppCell	10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like-AC-like-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NEUROD1 SHF EGFR NFIB KCNQ2 EXTL3 TBX1	7.19e-08	194	82	7	8b81f039f5b25d35a4d5a41b27d4d9360ba22f15
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-IPC_like\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	PRDM8 NEUROD1 GSE1 NFIB CECR2 KCNQ2 FOXG1	8.27e-08	198	82	7	6d12ecaa9532c134d9c4562534dcb59a6420b4d3
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-IPC_like-IPs_and_early_cortical_neurons\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	PRDM8 NEUROD1 GSE1 NFIB CECR2 KCNQ2 FOXG1	8.27e-08	198	82	7	7943e4f67c3d6efb5c8b00aa0ff3cfe7be10c48d
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-Neuronal-Neuron\|10w / Sample Type, Dataset, Time_group, and Cell type.	PRDM8 NEUROD1 GSE1 NFIB CECR2 KCNQ2	1.89e-06	200	82	6	332905a686356cd1e024d40679be98e9d8b1b5e8
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Neuronal-Neuron\|6m / Sample Type, Dataset, Time_group, and Cell type.	PRDM8 NEUROD1 SHF GSE1 KCNQ2 SOX8	1.89e-06	200	82	6	b5019b9d48f32cffd4645a5c0f3e0ac504ea8019
ToppCell	343B-Myeloid-Macrophage-SPP1+_Macrophage_2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	TCF7 CEP72 CD27 FRYL ZNF318	8.55e-06	150	82	5	744050a1b665c6989f37141348af3df7579a73c9
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Lamp5\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	EGFR NFIB ARX LTBP2 ARID5A	1.32e-05	164	82	5	08819970174a3eb4eee8e1e675075828665b845e
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c04-COTL1\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	FBXO3 RPRD2 POGZ WDR76 CSMD3	1.44e-05	167	82	5	3b717d33aaf1ef0869cc4bca8432ba8008875cc5
ToppCell	TCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma-Intrahepatic-2\|TCGA-Bile_Duct / Sample_Type by Project: Shred V9	CBLL1 RPRD2 LTBP2 PTCH1 SOD3	1.48e-05	168	82	5	c70bf73bb800e4722cedc35bbc17ea3113d1012d
ToppCell	E18.5-samps-Mesenchymal-Myofibroblast\|E18.5-samps / Age Group, Lineage, Cell class and subclass	TCF7 NFIB LTBP2 PTCH1 FOXF1	2.23e-05	183	82	5	de08f9ea02b7244d5a8788064631d10f06565337
ToppCell	tumor_Lung-Endothelial_cells-Lymphatic_ECs\|tumor_Lung / Location, Cell class and cell subclass	NFIB TRIOBP BCAR1 TBX1 SMAD1	2.48e-05	187	82	5	87ecdc5f24aced95a37e653429f0fc493ff4aa3e
ToppCell	wk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_1\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	TCF7L2 NFIB LTBP2 PTCH1 FOXF1	2.67e-05	190	82	5	d24af6af3271e34afab744352afd28be8a7cc5c3
ToppCell	nucseq\|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	TANC2 RGPD8 FOXN3 SIK3 ANKHD1	2.88e-05	193	82	5	779276e775cb2492e8dd36436295a536084a6415
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-OPC-like-OPC-like-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NFIB NLRP1 SOX8 SPAG17 SOD3	2.88e-05	193	82	5	c3522693439c23830d8a3f20854539ccb7a666e0
ToppCell	facs-Skin-Anagen-3m-Epithelial-outer_bulge\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HOXB9 NFIB DLGAP4 EXTL3 TBX1	2.95e-05	194	82	5	5d30d3d41d5f19cdf3077cc609aa2738762cb8c5
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-4\|TCGA-Prostate / Sample_Type by Project: Shred V9	ZNF469 MAP3K14 NLRP1 ARID5A FOXF1	3.02e-05	195	82	5	5562665dd3beb70e2358aa32611a337bef5731c1
ToppCell	IPF-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	TANC2 GSE1 ST6GALNAC5 LTBP2 FOXN3	3.18e-05	197	82	5	f304d42fc4936fe20996e07c8dccc698a6e5e5ef
ToppCell	10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NEUROD1 SHF EGFR KCNQ2 TBX1	3.25e-05	198	82	5	7225a6194c52b01c581e58d3cda107c4af96dc4f
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-5w-Neuronal-Intermediate\|5w / Sample Type, Dataset, Time_group, and Cell type.	TANC2 DLG5 ATN1 GSE1 ARX	3.41e-05	200	82	5	c92e4fc0442404481fcac623d691dae6215b852d
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DLG5 SH3RF2 FOXN3 CSMD3	1.16e-04	136	82	4	7cd22169fb71c6caf9feb203ad98be8480a54fba
ToppCell	PND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TCF7 THEMIS CD27 ARID5A	1.49e-04	145	82	4	a9f5a32abcf3eb2c66bd65f2521a6dd4ce56c635
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c05-FOS\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TCF7 THEMIS CD27 SOX8	1.57e-04	147	82	4	463af96748349c8fec2911b353a7e7e4cb072280
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-IPC_like\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	TCF7 NEUROD1 FBRSL1 KCNQ2	1.61e-04	148	82	4	a261c6d3d9cf0311c053fca66c37d39e66db6ad8
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-IPC_like-IPs_and_early_cortical_neurons\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	TCF7 NEUROD1 FBRSL1 KCNQ2	1.61e-04	148	82	4	c0237ba7d4040b6a497094b362dfb8b3a97a7d06
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PRTG PRDM8 MUC12 PTCH1	1.65e-04	149	82	4	aedbae2dffa1e880e5c6a146b6d5a135e7f54308
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-IPC_like\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	NEUROD1 GSE1 NFIB FOXG1	1.97e-04	156	82	4	7e6805ebc7bc2f9c5965321d16922c155719970f
ToppCell	3'_v3-Lung-Lymphocytic_T_CD8-Tnaive/CM_CD8\|Lung / Manually curated celltypes from each tissue	TCF7 THEMIS CD27 KCNQ2	1.97e-04	156	82	4	d691a4defda046c1bbcb13ef38ee9abbb628c33c
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-IPC_like-IPs_and_early_cortical_neurons\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	NEUROD1 GSE1 NFIB FOXG1	1.97e-04	156	82	4	741de05295b2d012ac8576378f37709a97c8fb50
ToppCell	wk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_2\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	NFIB LTBP2 PTCH1 FOXF1	2.02e-04	157	82	4	b9d04ee417c0d8ea0801d10f1c54e138587009fd
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PRTG SLC12A3 CECR2 LTBP2	2.07e-04	158	82	4	7960337d87afecf2692ab65e5991f052ceddfacc
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Lsp1\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	EGFR NFIB LTBP2 ARID5A	2.12e-04	159	82	4	0dccc4275b9b4f8554dd556da7218e130bff8fd1
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Lymphocytic-T_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC12A3 ERV3-1 CD27 PALM3	2.17e-04	160	82	4	97c899df1b57fd2bd1867e02bfedf1920c00ad17
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_neural-A\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PRDM8 NEUROD1 SHF GSE1	2.22e-04	161	82	4	bd520c9a1927d5d5355b4421e6b90b58bfb76a42
ToppCell	CV-Healthy-3\|CV / Virus stimulation, Condition and Cluster	ZSWIM8 PRDM8 TCF7L2 PIAS2	2.22e-04	161	82	4	fd4a79385ea967b9900dc76a3add813b894a3a28
ToppCell	facs-Lung-ENDOMUCIN-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCF7 CD27 INTS15 PALM3	2.33e-04	163	82	4	4af92b211d12c5b88b65bb746242cd702b545bd0
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Lsp1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	EGFR NFIB LTBP2 ARID5A	2.33e-04	163	82	4	bba830a302919c8b33f914a8839877fc21dd28a0
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	EGFR NFIB LTBP2 ARID5A	2.33e-04	163	82	4	8d17f44faf0549fe71a9a45f811f50d767275414
ToppCell	facs-Lung-ENDOMUCIN-18m-Lymphocytic-CD4+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCF7 CD27 INTS15 PALM3	2.33e-04	163	82	4	d24774e0aa612322c22fdb3b314aef275fa01d68
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c12-MKI67-TYROBP\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ZNF469 SH3RF2 FOXG1 TBX1	2.39e-04	164	82	4	4ef776d1bab4103d42d3a4f22cdfb49e8d2bc5a0
ToppCell	droplet-Liver-LIVER-NPC-1m-Lymphocytic-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THEMIS FRYL WDR76 SOD3	2.44e-04	165	82	4	8c7a6f9e2ca0ce077426d3d0726e3f5a4c03b296
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TCF7 THEMIS CD27 WDR76	2.44e-04	165	82	4	5f606959a060b1ae241217889560c6761ac73bbb
ToppCell	droplet-Lung-3m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2-17-52\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NOP9 ZFHX2 NLRP1 DOT1L	2.50e-04	166	82	4	de319c960b0cd90b294f677d1ea1b013a2ce2d53
ToppCell	3'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-L_cells_(PYY+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HOXB9 NEUROD1 ARX ZNF318	2.50e-04	166	82	4	eb9c81fa7573de7aff6670e7dad313f02129809f
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TCF7 THEMIS CD27 PALM3	2.56e-04	167	82	4	754e6412d3b9cc0b126e59593df2f5956b4712ef
ToppCell	3'-Child04-06-SmallIntestine-Epithelial-neuro-epithelial-L_cells_(PYY+)\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HOXB9 NEUROD1 SHF ARX	2.56e-04	167	82	4	5accd0bc7c95089feb2c09376d12cd8bd3773775
ToppCell	facs-Lung-18m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l21\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TCF7 THEMIS CD27 PALM3	2.61e-04	168	82	4	6c758eb120faf06ff72d157b495e399191c79ec9
ToppCell	PND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TCF7 THEMIS CD27 WDR76	2.61e-04	168	82	4	ade02beb8d663fce4be2aefa10392ab849a4bbe7
ToppCell	facs-Lung-18m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TCF7 THEMIS CD27 PALM3	2.61e-04	168	82	4	68ee3b3b012b56584e313813feb16e632e3f72d2
ToppCell	10x3'2.3-week_12-13-Lymphocytic_T-T_NK-Treg\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	PRDM8 TCF7 THEMIS CD27	2.61e-04	168	82	4	99117480687e2b8e7521d3ae9e020791757ec48e
ToppCell	Int-URO-Lymphocyte-T_NK-CD4_TEM\|Int-URO / Disease, Lineage and Cell Type	TCF7 THEMIS CD27 KCNQ2	2.67e-04	169	82	4	5b2fb89cbc9b92d609994d6e5aa35a67c3cc8f22
ToppCell	facs-Heart-LV-18m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DLG5 PRDM8 EGFR SOD3	2.67e-04	169	82	4	849a8f8509c58d65462a09c84d58b6ecdc8934f5
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-OPC-like-OPC-like_Prolif-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PRTG EGFR NFIB FRYL	2.67e-04	169	82	4	2833a8a7094e4d407eb923f2bc59b9b112c6bae4
ToppCell	normal_Pleural_Fluid-Myeloid_cells-CD163+CD14+_DCs\|Myeloid_cells / Location, Cell class and cell subclass	CD27 STRADA TMEM39B NLRP1	2.67e-04	169	82	4	bea8aba1f3cc3d0e8d448c1c45f5354d26ebf850
ToppCell	droplet-Lung-nan-18m-Lymphocytic-Regulatory_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCF7 THEMIS CD27 SH3RF2	2.74e-04	170	82	4	064786c1f1ad7665358964765910b0ad46d14685
ToppCell	facs-Lung-18m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l5\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TCF7 THEMIS CD27 PALM3	2.74e-04	170	82	4	67e78e3c1d4cd3c6eaa5d0a9785b6cd8a3b08039
ToppCell	droplet-Lung-nan-18m-Lymphocytic-regulatory_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCF7 THEMIS CD27 SH3RF2	2.74e-04	170	82	4	6725747df336697708b94999b3ebb40f1721da16
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-regulatory_T_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TCF7 THEMIS CD27 SH3RF2	2.80e-04	171	82	4	10492832db8ebc3cf85503c441f33bd94df9458e
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-regulatory_T_cell-regulatory_T_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TCF7 THEMIS CD27 SH3RF2	2.80e-04	171	82	4	7c0a1b0676f6749ee710c6bdeca6d6f7fac79b69
ToppCell	facs-GAT-Fat-24m-Lymphocytic-CD8-positive,_alpha-beta_T_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCF7 THEMIS CD27 ARID5A	2.86e-04	172	82	4	a9f0ccaca0d83bfec79e3251e346a165c34c242b
ToppCell	Globus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	NEUROD1 ACTL9 PROP1	2.92e-04	70	82	3	677deb7c7c100756a4cdc788d61feb45039a9a97
ToppCell	facs-Lung-EPCAM-18m-Lymphocytic-CD4+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCF7 THEMIS CD27 PALM3	2.99e-04	174	82	4	fedadde222df1952d6456f4f3413c01579146e1f
ToppCell	facs-Lung-EPCAM-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCF7 THEMIS CD27 PALM3	2.99e-04	174	82	4	e69a011ae9698368923223d3af3243e609c08c83
ToppCell	5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PRTG EGFR PTCH1 CSMD3	2.99e-04	174	82	4	f90ca117b729436cf452e2ddcec26ba525c5c13b
ToppCell	facs-SCAT-Fat-24m-Lymphocytic-T_cell\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCF7 THEMIS CD27 ZFHX2	2.99e-04	174	82	4	6ca9433d398aa3b48ecdc522dd545119e7c77dd4
ToppCell	facs-BAT-Fat-18m-Lymphocytic-T_cell\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCF7 THEMIS CD27 ARID5A	3.05e-04	175	82	4	bf1ef77d5fed2135ac83a4f7e445ab59d1538696
ToppCell	AT1-AT2_cells-HP_01\|World / lung cells shred on cell class, cell subclass, sample id	SH3RF2 ST6GALNAC5 PALM3 VGLL1	3.05e-04	175	82	4	9a95ab5c361ebaa8747983c5a0d69025682a19ad
ToppCell	3'-Adult-Distal_Rectal-Epithelial-Tuft-related-Microfold_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MUC12 SOX8 FOXG1 SOD3	3.05e-04	175	82	4	8a37b2811f39bb9baa537e8755a29d559eb8185a
ToppCell	facs-Skin-nan-24m-Epithelial-outer_bulge\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NFIB ZFHX2 LTBP2 TBX1	3.05e-04	175	82	4	f1166b567bca80dac3abe90c3dc544c831006640
ToppCell	facs-Trachea-nan-18m-Lymphocytic-nan\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCF7 THEMIS CD27 PALM3	3.12e-04	176	82	4	14c6c3fdb53f9dfc02b951bc955b90213110c089
ToppCell	Control-Lymphocyte-T_NK-CD8_TCM\|Control / Disease, Lineage and Cell Type	TCF7 THEMIS CD27 KCNQ2	3.12e-04	176	82	4	1a7948eb86ee1da607db4d0576312b2859d94523
ToppCell	facs-Trachea-nan-18m-Lymphocytic\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCF7 THEMIS CD27 PALM3	3.12e-04	176	82	4	9dd862dcee6947a53189728f6b4cd40e7b67cb71
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DLG5 EGFR FOXN3 CSMD3	3.12e-04	176	82	4	6c7edf1cb38644500bce6c5a1dd90bbe17415cdb
ToppCell	normal_Pleural_Fluid-Myeloid_cells-CD163+CD14+_DCs\|normal_Pleural_Fluid / Location, Cell class and cell subclass	TANC2 STRADA TMEM39B NLRP1	3.12e-04	176	82	4	7a74217b7fa1032b918f00a3972dff5fab74671a
ToppCell	facs-Trachea-nan-18m-Lymphocytic-T_cell\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCF7 THEMIS CD27 PALM3	3.12e-04	176	82	4	d990e7af8120210100d13caa0465b27cf77a451a
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DLG5 EGFR FOXN3 CSMD3	3.26e-04	178	82	4	51d2188406f04329311b2efd1108fc36617a860e
ToppCell	3'-Adult-Distal_Rectal-Epithelial-Tuft-related\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MUC12 SOX8 FOXG1 SOD3	3.26e-04	178	82	4	a95bb77a2c2ce7c38989e6f971812f7ee9f5bd4b
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF469 NEUROD1 SH3RF2 ST6GALNAC5	3.26e-04	178	82	4	ccea3c8908d72f5fecd151a133048c8e9758304c
ToppCell	10x3'2.3-week_12-13-Mesenchymal_osteo-stroma-early_osteoblast\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	PRTG GLI2 ARX PTCH1	3.26e-04	178	82	4	e32f5ed7a492edfa7073416008b1fcfae6b854ad
ToppCell	COVID-19-Heart-Lymph_EC\|Heart / Disease (COVID-19 only), tissue and cell type	TANC2 PRDM8 TBX1 SMAD1	3.33e-04	179	82	4	411620201a860716a8773b92f50f7b94ef34a586
ToppCell	3'-Child09-12-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HOXB9 NEUROD1 ST6GALNAC5 SPAG17	3.33e-04	179	82	4	8ce5000088b727783a0619baa16a2cd036d21f54
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	EGFR FOXN3 SIK3 CSMD3	3.40e-04	180	82	4	cfc8bfbfd3617aabbb49f9730c29b673ca157e74
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-5\|TCGA-Colorectal / Sample_Type by Project: Shred V9	TCF7L2 SH3RF2 TRIOBP PIAS2	3.47e-04	181	82	4	8fcc9e77fee7c248df26b6c59b10e672242e2084
ToppCell	facs-MAT-Fat-18m-Lymphocytic-CD8-positive,_alpha-beta_T_cell\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCF7 THEMIS CD27 ARID5A	3.47e-04	181	82	4	6bb4b19f7804319dd7cfa450c7d1c7b4e90f2450
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRDM8 SLC12A3 CECR2 FOXF1	3.62e-04	183	82	4	bc24145855bf4d027a8058bf92bc796c10f241bb
ToppCell	Healthy-CD8+_T_naive\|Healthy / disease group, cell group and cell class	TCF7 THEMIS CD27 SOX8	3.62e-04	183	82	4	5e7a611cfb8a21106bb07361878ccc77ff251502
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DLGAP4 PALM3 DOT1L PIAS2	3.62e-04	183	82	4	91079a11685dd466bd27a0cf5afbf3734c08a05e
ToppCell	10x5'v1-week_17-19-Lymphocytic_T-T_NK-Treg\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	PRDM8 TCF7 THEMIS CD27	3.62e-04	183	82	4	5fb933acfe6bc555c90dba71e75d4be658763945
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF469 NEUROD1 SH3RF2 ST6GALNAC5	3.62e-04	183	82	4	1645d4a55cd8c22d6eb47fc5c6b1e576c454f111
ToppCell	wk_20-22-Mesenchymal-Myofibro_&_SMC-Myofibro_3\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	HOXB9 NFIB PTCH1 FOXF1	3.62e-04	183	82	4	f4ea7113ce9099222743d9ff02388d3d8a9e987b
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRDM8 SLC12A3 CECR2 FOXF1	3.62e-04	183	82	4	4c325ee6da070513097a11445ec95b0415ffd8a2
ToppCell	CV-Healthy-7\|CV / Virus stimulation, Condition and Cluster	TCF7 GSE1 RGPD8 TEP1	3.69e-04	184	82	4	0e5cc77aaa73ceb791f8be7456177577fd2e5586
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF469 NEUROD1 SH3RF2 ST6GALNAC5	3.69e-04	184	82	4	34e316ad8e7b8667cd8ad61397281802a252744f
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NEUROD1 EGFR SH3RF2 ST6GALNAC5	3.69e-04	184	82	4	30fddbc9696476d4d7f08e53f84ea994a4ed873a
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NEUROD1 EGFR SH3RF2 ST6GALNAC5	3.69e-04	184	82	4	96926efa220f03d0787322c9519bb9e8f64f74d0
ToppCell	5'-Adult-LargeIntestine-Hematopoietic-T_cells-SELL+_CD8_T\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TCF7 THEMIS NLRP1 ARID5A	3.69e-04	184	82	4	d5b8604142ae70abbfa4ea881ce55b2a3a2a46a6
ToppCell	15-Trachea-Epithelial-Multiciliated_precursor\|Trachea / Age, Tissue, Lineage and Cell class	ZNF469 FOXN4 MUC12 SPAG17	3.77e-04	185	82	4	9a8b8360d99375b726ca8e3c9a3f9b08919892d7
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HOXB9 HOXC11 ARX CSMD3	3.85e-04	186	82	4	bdc87e4631a8ea73e262e541aa84a28f24c94b00
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TANC2 MUC12 PTCH1 FOXF1	3.85e-04	186	82	4	8ea708070166c858cd9bd871670655b0114c32a5
ToppCell	5'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell-CD4_T_cells-CD4_T_cells_L.1.1.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TCF7 THEMIS CD27 KCNQ2	3.92e-04	187	82	4	c0a18ab7d88420e20e478ccdce6a2cb0a60a7824
ToppCell	Control-Lymphocyte-T_NK-CD8_Naive\|Control / Disease, Lineage and Cell Type	TCF7 THEMIS CD27 SOX8	3.92e-04	187	82	4	cf8bebef36e1ec76a22f229e5c073b3a201d1b93
Drug	Mebendazole [31431-39-7]; Down 200; 13.6uM; PC3; HT_HG-U133A	TANC2 HOXB9 TCF7L2 ATN1 FBXO3 NFIB DLGAP4 NLRP1	4.13e-07	194	80	8	3671_DN
Drug	glyphosate	HOXB9 HOXC11 FOXN4 CD27 GLI2 FOXN3 PTCH1 FOXF1	8.98e-07	215	80	8	CID000003496
Drug	Nimodipine [66085-59-4]; Down 200; 9.6uM; HL60; HT_HG-U133A	MRPL4 TCF7L2 DLGAP4 INTS15 LTBP2 WDR76 SMAD1	5.31e-06	193	80	7	3103_DN
Drug	Butylparaben [94-26-8]; Down 200; 20.6uM; HL60; HT_HG-U133A	DLGAP4 INTS15 ZFHX2 NLRP1 PTCH1 ARID5A FOXG1	5.88e-06	196	80	7	3069_DN
Drug	Acetopromazine maleate salt [3598-37-6]; Down 200; 9uM; MCF7; HT_HG-U133A	TCF7 CEP72 POGZ EXTL3 WDR76 TEP1	6.31e-05	194	80	6	6832_DN
Drug	0179445-0000 [211246-22-9]; Down 200; 1uM; MCF7; HT_HG-U133A	ATN1 EGFR DLGAP4 LTBP2 FOXN3 EXTL3	6.31e-05	194	80	6	4758_DN
Drug	Sulfapyridine [144-83-2]; Down 200; 16uM; MCF7; HT_HG-U133A	TCF7 TMEM39B POGZ WDR76 TEP1 FOXG1	6.49e-05	195	80	6	6799_DN
Drug	Betonicine [515-25-3]; Up 200; 25.2uM; MCF7; HT_HG-U133A	TCF7 NEUROD1 ZFHX2 NLRP1 POGZ PIAS2	6.49e-05	195	80	6	3642_UP
Drug	Apramycin [37321-09-8]; Up 200; 7.4uM; HL60; HT_HG-U133A	DLG5 NFIB DLGAP4 NLRP1 EXTL3 SOD3	6.67e-05	196	80	6	2914_UP
Drug	Loracarbef [121961-22-6]; Down 200; 10.8uM; PC3; HT_HG-U133A	RALGAPA1 ATN1 NFIB TRIOBP FOXN3 EXTL3	6.67e-05	196	80	6	5073_DN
Drug	Fenspiride hydrochloride [5053-08-7]; Down 200; 13.4uM; MCF7; HT_HG-U133A	RALGAPA1 DLG5 ZFHX2 LTBP2 FOXN3 FOXG1	6.86e-05	197	80	6	2269_DN
Drug	Trichlormethiazide [133-67-5]; Up 200; 10.6uM; PC3; HT_HG-U133A	HOXC11 PTCH1 ARID5A TBX1 SMAD1 SOD3	6.86e-05	197	80	6	4198_UP
Drug	Mexiletine hydrochloride [5370-01-4]; Down 200; 18.6uM; MCF7; HT_HG-U133A	TCF7L2 ATN1 NFIB ZFHX2 TMEM39B FOXG1	6.86e-05	197	80	6	2324_DN
Drug	Azaperone [1649-18-9]; Down 200; 12.2uM; MCF7; HT_HG-U133A	DLG5 TCF7L2 DLGAP4 ZNF318 TEP1 FOXG1	6.86e-05	197	80	6	7231_DN
Drug	haloperidol; Up 200; 10uM; HL60; HT_HG-U133A	ZSWIM8 ATN1 TRIOBP ZFHX2 LTBP2 PTCH1	7.06e-05	198	80	6	6163_UP
Drug	Fenofibrate [49562-28-9]; Down 200; 11uM; MCF7; HT_HG-U133A	TCF7 DLGAP4 TRIOBP LTBP2 ZNF318 SIK3	7.06e-05	198	80	6	7474_DN
Drug	Todralazine hydrochloride [3778-76-5]; Up 200; 14.8uM; PC3; HT_HG-U133A	RALGAPA1 TCF7 HOXC11 GLI2 FOXN3 TBX1	7.06e-05	198	80	6	5087_UP
Drug	Demeclocycline hydrochloride [64-73-3]; Down 200; 8uM; PC3; HT_HG-U133A	HOXC11 ATN1 NFIB DLGAP4 FOXN3 FOXG1	7.06e-05	198	80	6	3706_DN
Drug	Kanamycin A sulfate [25389-94-0]; Up 200; 6.8uM; MCF7; HT_HG-U133A	ATN1 SLC12A3 EGFR ST6GALNAC5 FOXN3 TBX1	7.26e-05	199	80	6	5686_UP
Drug	Alverine citrate salt [5560-59-8]; Down 200; 8.4uM; MCF7; HT_HG-U133A	ATN1 EGFR ZFHX2 FOXN3 EXTL3 FOXG1	7.26e-05	199	80	6	2273_DN
Drug	Sulfamethoxazole [723-46-6]; Up 200; 15.8uM; PC3; HT_HG-U133A	TCF7L2 EGFR FOXN3 PTCH1 WDR76 SOD3	7.26e-05	199	80	6	7366_UP
Drug	Leucomisine [17946-87-1]; Up 200; 16.2uM; MCF7; HT_HG-U133A	ZSWIM8 TCF7L2 DLGAP4 FOXN3 FOXG1 SMAD1	7.26e-05	199	80	6	3546_UP
Drug	1,4-diaminocyclohexane	GLI2 PTCH1	7.28e-05	4	80	2	ctd:C088969
Drug	NodRm-1	ATN1 NLRP1	7.28e-05	4	80	2	CID006450093
Drug	Esculin Hydrate [531-75-9]; Down 200; 11.8uM; HL60; HT_HG-U133A	TANC2 HOXB9 TCF7L2 MAP3K14 NLRP1 PTCH1	7.46e-05	200	80	6	3052_DN
Drug	tiopronin	NLRP1 TEP1 SOD3	9.09e-05	25	80	3	CID000005483
Disease	Neurodevelopmental Disorders	TANC2 TCF7L2 KCNQ2 POGZ FOXG1	4.91e-06	93	78	5	C1535926
Disease	pulse pressure measurement	MRPL4 PRDM8 TCF7L2 DLGAP4 FBRSL1 TRIOBP FRYL LTBP2 ZNF318 POGZ GPATCH8 BCAR1 DOT1L ARID5A	1.53e-05	1392	78	14	EFO_0005763
Disease	cortical surface area measurement	TANC2 PRTG ZNF469 TCF7L2 EGFR NFIB MAP3K14 TRIOBP FRYL EXTL3 PTCH1 SPAG17 FOXG1	4.82e-05	1345	78	13	EFO_0010736
Disease	Basal Cell Nevus Syndrome	GLI2 PTCH1	6.86e-05	5	78	2	C0004779
Disease	Dystonia	ARX FBXO7 KCNQ2 FOXG1	8.14e-05	86	78	4	C0013421
Disease	Pituitary Hormone Deficiency, Combined, 1	GLI2 PROP1	1.03e-04	6	78	2	C2751608
Disease	fish oil supplement exposure measurement, high density lipoprotein cholesterol measurement	SLC12A3 SIK3	1.44e-04	7	78	2	EFO_0004612, EFO_0600007
Disease	Glycosuria	TCF7L2 NEUROD1	1.44e-04	7	78	2	HP_0003076
Disease	Gastrointestinal Stromal Sarcoma	GLI2 PTCH1 FOXF1	2.65e-04	47	78	3	C3179349
Disease	Holoprosencephaly sequence	GLI2 PTCH1	3.06e-04	10	78	2	cv:C0079541
Disease	Gastrointestinal Stromal Tumors	GLI2 PTCH1 FOXF1	3.18e-04	50	78	3	C0238198
Disease	breast carcinoma	TCF7L2 SLC12A3 EGFR GLI2 FOXN3 SIK3 DOT1L PTCH1 SPAG17 TBX1	3.46e-04	1019	78	10	EFO_0000305
Disease	nervous system disorder	NEUROD1 KCNQ2 FOXG1	3.78e-04	53	78	3	C0027765
Disease	Alobar Holoprosencephaly	GLI2 PTCH1	7.08e-04	15	78	2	C0431363
Disease	autism spectrum disorder (implicated_via_orthology)	SH3RF2 DLGAP4 POGZ TBX1	7.18e-04	152	78	4	DOID:0060041 (implicated_via_orthology)
Disease	Lobar Holoprosencephaly	GLI2 PTCH1	8.08e-04	16	78	2	C0431362
Disease	Semilobar Holoprosencephaly	GLI2 PTCH1	8.08e-04	16	78	2	C0751617
Disease	Holoprosencephaly	GLI2 PTCH1	9.14e-04	17	78	2	C0079541
Disease	Familial Progressive Myoclonic Epilepsy	PRDM8 ATN1	9.14e-04	17	78	2	C0751777
Disease	Atypical Inclusion-Body Disease	PRDM8 ATN1	9.14e-04	17	78	2	C0751776
Disease	Myoclonic Epilepsies, Progressive	PRDM8 ATN1	9.14e-04	17	78	2	C0751778
Disease	Biotin-Responsive Encephalopathy	PRDM8 ATN1	9.14e-04	17	78	2	C0751780
Disease	May-White Syndrome	PRDM8 ATN1	9.14e-04	17	78	2	C0751782
Disease	Dentatorubral-Pallidoluysian Atrophy	PRDM8 ATN1	9.14e-04	17	78	2	C0751781
Disease	stomach cancer (is_implicated_in)	GSE1 PTCH1 TEP1	9.29e-04	72	78	3	DOID:10534 (is_implicated_in)
Disease	Action Myoclonus-Renal Failure Syndrome	PRDM8 ATN1	1.03e-03	18	78	2	C0751779
Disease	Intellectual Disability	TANC2 RALGAPA1 ATN1 NFIB POGZ FOXG1	1.20e-03	447	78	6	C3714756
Disease	corneal hysteresis	ZNF469 TCF7L2	1.27e-03	20	78	2	EFO_0010066
Disease	Cleft Palate	ATN1 PTCH1 TBX1	1.31e-03	81	78	3	C0008925
Disease	osteoarthritis, hip	RPRD2 LTBP2 SPAG17	1.88e-03	92	78	3	EFO_1000786
Disease	red blood cell density measurement	RALGAPA1 PRDM8 TCF7L2 STRADA FBXO7 FBRSL1 PALM3 SIK3	2.26e-03	880	78	8	EFO_0007978
Disease	Pancreatic Neoplasm	EGFR BCAR1 PTCH1	2.39e-03	100	78	3	C0030297
Disease	TYPE 2 DIABETES MELLITUS	TCF7L2 NEUROD1	2.49e-03	28	78	2	125853
Disease	Pigmented Basal Cell Carcinoma	GLI2 PTCH1	2.49e-03	28	78	2	C1368275
Disease	Type 2 diabetes mellitus	TCF7L2 NEUROD1	2.49e-03	28	78	2	cv:C0011860
Disease	Malignant neoplasm of pancreas	EGFR BCAR1 PTCH1	2.53e-03	102	78	3	C0346647
Disease	sexual dimorphism measurement	RALGAPA1 SLC12A3 GLI2 DLGAP4 FRYL LTBP2 SIK3 DOT1L PTCH1	2.54e-03	1106	78	9	EFO_0021796
Disease	Colorectal Carcinoma	TCF7L2 GSE1 EGFR ACTL9 SPAG17 CSMD3 TBX1	2.57e-03	702	78	7	C0009402

Protein segments in the cluster

Peptide	Gene	Start	Entry
SPHPSPFSRFPSLNH	ERV3-1	386	Q14264
HQHTFAPFPAGLPPT	FBRSL1	456	Q9HCM7
HPMDHPSAFYSPPHN	AKAP2	21	Q9Y2D5
APPVTTYAAPHFFHL	ARID5A	576	Q03989
SGFILSPNFPHPYPH	CSMD3	1596	Q7Z407
SPNFPHPYPHSRDCD	CSMD3	1601	Q7Z407
LSPHPQPTHLPYVSE	CD27	136	P26842
QTPHHPFPSPATDLY	BCAR1	151	P56945
HPSYLAPHPFPHPAF	GSE1	251	Q14687
ASFEPHPSVTPTGYH	ATN1	181	P54259
ASPFPASQALPSYPH	ATN1	396	P54259
PAHLPPPHSQVSYSQ	ATN1	546	P54259
THDHPLLFSDPPFSP	ACTL9	141	Q8TC94
PRPHTYFTPHPDSMD	CEP72	291	Q9P209
PHSPFYQLPPSVQRH	DOT1L	456	Q8TEK3
HYAPPPSPSSPVNHQ	CBLL2	281	Q8N7E2
RAYSSPVAALPPHHP	CECR2	1381	Q9BXF3
PPSSTFPRIHYNSHF	DLGAP4	66	Q9Y2H0
QAILPPAPSSYFSHP	NFIB	371	O00712
SHHSSYQPLCLPFPV	RGPD5	506	Q99666
SHHSSYQPLCLPFPV	RGPD8	506	O14715
SPHAALPPGFYPHIH	INTS15	396	Q96N11
SANPSAHPVPTYAPA	PALM3	631	A6NDB9
PDSHPHLSPEALGYF	NOP9	51	Q86U38
PFTFHPVPHAALYPT	GPATCH8	1451	Q9UKJ3
SFLPELSSVHPPHYF	FBXO3	291	Q9UK99
AGQTSYFFPHVPHPS	FOXG1	411	P55316
PAPPYHSPEDSREHV	KCNQ2	666	O43526
GHSPSFPYSPSEPHL	NLRP1	91	Q9C000
HPPPLERSPYSNVFH	FRYL	671	O94915
LQFDYPPPATPHCTA	COIL	11	P38432
SPGHSSRHSNPPLYP	DLG5	1156	Q8TDM6
GESPFNAPHPYVNPH	GLI2	111	P10070
PPPPPHHLYAKANTS	PRTG	721	Q2VWP7
LSPHASGSLPSVYHP	HOXB9	66	P17482
VTAPPPHHYNPNSLP	CBLL1	416	Q75N03
PPSPPTHRAHHVYPS	POM121	186	Q96HA1
NPAPSRDPHYQDPHS	EGFR	1116	P00533
CPPDYVPPEIFHFHT	DPP9	601	Q86TI2
PSSTHTIPFYPNPLH	FBXO7	416	Q9Y3I1
FHLFPHTPFDPVLPS	EXTL3	611	O43909
TPYHPHPHVFNTPPT	FOXN3	206	O00409
HPHVFNTPPTCPQAY	FOXN3	211	O00409
PSELQPHYVASHPEP	LTBP2	1711	Q14767
PHYVASHPEPPAGFE	LTBP2	1716	Q14767
HPSAPHATPAGFYSS	HOXC11	126	O43248
SPYLDASPFPPHHPA	ARX	411	Q96QS3
QYPDSPHPVPHRSLF	RPRD2	961	Q5VT52
CLHPPPSSVPYFHGE	CPHXL	251	A0A1W2PPM1
PPSLTDYSVPFHHTP	PIAS2	526	O75928
HPFPYSRLPHPFPFH	MAP3K14	256	Q99558
PPYPQPHVAVHSSQE	FOXN4	171	Q96NZ1
YPHHDSSVPASPLLP	FOXF1	236	Q12946
IPSHFPEFPDPHTYI	TAF8	146	Q7Z7C8
TPRPSNGDSPSHPYH	STRADA	331	Q7RTN6
NGDSPSHPYHRTFSP	STRADA	336	Q7RTN6
PLPHATQGPAATPYH	MRPL4	296	Q9BYD3
PDFPNHFPTYVHCSL	POGZ	761	Q7Z3K3
GPLHHYPSPSPESSN	PRDM8	231	Q9NQV8
PPPPYSSHSFAHETQ	PTCH1	641	Q13635
FPPSAHQQPPHYTTS	SIK3	931	Q9Y2K2
SHYRPSPPHTSPAHQ	TANC2	1496	Q9HCD6
PDFCRDPNHPSVPYH	ST6GALNAC5	256	Q9BVH7
PPAHSPTSHWDQPVY	SOX8	426	P57073
ASSPPRYLQHDPFPF	TRIOBP	1026	Q9H2D6
ESPHQPEPKITYPFH	SPAG17	1006	Q6Q759
SHPFPHSPNSSYPNS	SMAD1	181	Q15797
SSFPVSLPLAYPHPH	ANKHD1	1841	Q8IWZ3
YESSASHPPPRPPKH	THEMIS	546	Q8N1K5
SPPFSSVPEIVHHYA	SHF	386	Q7M4L6
HPNYPPAHLLPTSSL	PP632	51	Q6XCG6
PFLAYPPPSHLTALH	ZFHX2	156	Q9C0A1
VFSPAPYHHLPSDAD	RALGAPA1	2021	Q6GYQ0
PPSYNLPDHPHFHWA	TEP1	981	Q99973
ESTGPHYNPLAVPHP	SOD3	126	P08294
YSNEHFTPGNPPPHL	TCF7L2	206	Q9NQB0
PSPPAAYDSSHPSHL	SLC12A3	31	P55017
CFPHPYSHALPSQPS	PROP1	166	O75360
SLYEHFNSPHPTPAP	TCF7	161	P36402
PRAPPPYPTHHFSLS	ZNF469	706	Q96JG9
HPYTALQPHLPCSPQ	ZSWIM8	1506	A7E2V4
FHPHSQPVSCLYFSP	WDR76	356	Q9H967
QNYSPPPTKHYTSHP	SH3RF2	646	Q8TEC5
DPATPGRVHYHPDSP	TBX1	186	O43435
YSHPFPARHLVPEPQ	VGLL1	146	Q99990
SSQDHPLYSGHPSLP	ZNF318	406	Q5VUA4
HSPFSGSLHAPPAFY	VENTX	156	O95231
YPPSHPPSHTSLNFH	TMEM39B	106	Q9GZU3
YHRSPGSTPTTHFPA	MUC12	2721	Q9UKN1
HLPTASASFPVHPYS	NEUROD1	206	Q13562