Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	growth factor binding	TSKU ERBB4 KL EPHA2 LRP2 LTBP4	3.34e-05	156	78	6	GO:0019838
GeneOntologyMolecularFunction	extracellular matrix structural constituent	MATN2 LAMA5 MUC2 LTBP4 SSPOP FBN3	9.41e-05	188	78	6	GO:0005201
GeneOntologyMolecularFunction	calcium ion binding	EYS CAMKK2 SUSD1 DSG3 MATN2 NOTCH2NLA LRP2 NOTCH2NLC LTBP4 FBN3 NOTCH4	1.51e-04	749	78	11	GO:0005509
GeneOntologyBiologicalProcess	mammary gland development	FASN ERBB4 KALRN EPHA2 INSL4 RREB1 NOTCH4	2.68e-06	162	78	7	GO:0030879
GeneOntologyCellularComponent	extracellular matrix	TSKU EYS SMC3 MAMDC2 MATN2 LAMA5 MUC2 LTBP4 SSPOP FBN3	1.77e-04	656	79	10	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	TSKU EYS SMC3 MAMDC2 MATN2 LAMA5 MUC2 LTBP4 SSPOP FBN3	1.82e-04	658	79	10	GO:0030312
Domain	EGF_2	EYS SUSD1 EPHA2 MATN2 NOTCH2NLA LRP2 LAMA5 NOTCH2NLC LTBP4 SSPOP ADAM22 FBN3 NOTCH4	8.08e-11	265	79	13	PS01186
Domain	ASX_HYDROXYL	EYS SUSD1 MATN2 NOTCH2NLA LRP2 NOTCH2NLC LTBP4 FBN3 NOTCH4	3.78e-10	100	79	9	PS00010
Domain	EGF-type_Asp/Asn_hydroxyl_site	EYS SUSD1 MATN2 NOTCH2NLA LRP2 NOTCH2NLC LTBP4 FBN3 NOTCH4	6.40e-10	106	79	9	IPR000152
Domain	EGF-like_CS	EYS SUSD1 EPHA2 MATN2 NOTCH2NLA LRP2 LAMA5 NOTCH2NLC LTBP4 ADAM22 FBN3 NOTCH4	9.62e-10	261	79	12	IPR013032
Domain	Growth_fac_rcpt_	EYS ERBB4 SUSD1 EPHA2 MATN2 LRP2 LAMA5 LTBP4 FBN3 NOTCH4	1.09e-09	156	79	10	IPR009030
Domain	EGF_CA	EYS SUSD1 MATN2 NOTCH2NLA LRP2 NOTCH2NLC LTBP4 FBN3 NOTCH4	2.25e-09	122	79	9	SM00179
Domain	EGF-like_Ca-bd_dom	EYS SUSD1 MATN2 NOTCH2NLA LRP2 NOTCH2NLC LTBP4 FBN3 NOTCH4	2.60e-09	124	79	9	IPR001881
Domain	EGF_CA	SUSD1 MATN2 NOTCH2NLA LRP2 NOTCH2NLC LTBP4 FBN3 NOTCH4	2.90e-09	86	79	8	PF07645
Domain	EGF_3	EYS SUSD1 MATN2 NOTCH2NLA LRP2 NOTCH2NLC LTBP4 SSPOP ADAM22 FBN3 NOTCH4	4.22e-09	235	79	11	PS50026
Domain	EGF	EYS SUSD1 MATN2 NOTCH2NLA LRP2 LAMA5 NOTCH2NLC LTBP4 ADAM22 FBN3 NOTCH4	4.22e-09	235	79	11	SM00181
Domain	EGF_Ca-bd_CS	EYS SUSD1 NOTCH2NLA LRP2 NOTCH2NLC LTBP4 FBN3 NOTCH4	7.61e-09	97	79	8	IPR018097
Domain	EGF-like_dom	EYS SUSD1 MATN2 NOTCH2NLA LRP2 LAMA5 NOTCH2NLC LTBP4 ADAM22 FBN3 NOTCH4	7.71e-09	249	79	11	IPR000742
Domain	EGF_CA	EYS SUSD1 NOTCH2NLA LRP2 NOTCH2NLC LTBP4 FBN3 NOTCH4	8.95e-09	99	79	8	PS01187
Domain	EGF_1	EYS SUSD1 NOTCH2NLA LRP2 LAMA5 NOTCH2NLC LTBP4 SSPOP ADAM22 FBN3 NOTCH4	9.87e-09	255	79	11	PS00022
Domain	EGF	EYS MATN2 NOTCH2NLA LRP2 NOTCH2NLC FBN3 NOTCH4	1.04e-06	126	79	7	PF00008
Domain	TIL_dom	LRP2 MUC2 SSPOP	2.56e-05	14	79	3	IPR002919
Domain	Galactose-bd-like	GLB1 EPHA2 LAMA5 PTPRU SSPOP	4.87e-05	94	79	5	IPR008979
Domain	EPHD	KMT2D JADE2 RAI1	1.06e-04	22	79	3	PS51805
Domain	cEGF	MATN2 LRP2 FBN3	1.77e-04	26	79	3	IPR026823
Domain	cEGF	MATN2 LRP2 FBN3	1.77e-04	26	79	3	PF12662
Domain	hEGF	EYS FBN3 NOTCH4	2.21e-04	28	79	3	PF12661
Domain	TNFR/NGFR_Cys_rich_reg	CD40 LAMA5 TNFRSF10B	3.63e-04	33	79	3	IPR001368
Domain	TB	LTBP4 FBN3	3.66e-04	7	79	2	PF00683
Domain	-	LTBP4 FBN3	4.87e-04	8	79	2	3.90.290.10
Domain	TB	LTBP4 FBN3	6.24e-04	9	79	2	PS51364
Domain	TB_dom	LTBP4 FBN3	6.24e-04	9	79	2	IPR017878
Domain	TIL	MUC2 SSPOP	1.13e-03	12	79	2	PF01826
Domain	C8	MUC2 SSPOP	1.13e-03	12	79	2	PF08742
Domain	Unchr_dom_Cys-rich	MUC2 SSPOP	1.34e-03	13	79	2	IPR014853
Domain	C8	MUC2 SSPOP	1.34e-03	13	79	2	SM00832
Domain	VWD	MUC2 SSPOP	2.04e-03	16	79	2	SM00216
Domain	VWF_type-D	MUC2 SSPOP	2.04e-03	16	79	2	IPR001846
Domain	MAM_1	MAMDC2 PTPRU	2.04e-03	16	79	2	PS00740
Domain	VWFD	MUC2 SSPOP	2.04e-03	16	79	2	PS51233
Domain	VWD	MUC2 SSPOP	2.04e-03	16	79	2	PF00094
Domain	Acyl_Trfase/lysoPLipase	FASN PNPLA3	2.31e-03	17	79	2	IPR016035
Domain	MAM	MAMDC2 PTPRU	2.31e-03	17	79	2	SM00137
Domain	MAM	MAMDC2 PTPRU	2.59e-03	18	79	2	PF00629
Domain	MAM_dom	MAMDC2 PTPRU	2.59e-03	18	79	2	IPR000998
Domain	MAM_2	MAMDC2 PTPRU	2.59e-03	18	79	2	PS50060
Domain	CTCK_1	MUC2 SSPOP	2.59e-03	18	79	2	PS01185
Domain	VWC_out	MUC2 SSPOP	2.88e-03	19	79	2	SM00215
Domain	-	GLB1 EPHA2 SSPOP	3.66e-03	73	79	3	2.60.120.260
Domain	TNFR_c6	CD40 TNFRSF10B	3.86e-03	22	79	2	PF00020
Domain	fn3	FNDC7 KALRN EPHA2 PTPRU	4.95e-03	162	79	4	PF00041
Domain	Cys_knot_C	MUC2 SSPOP	4.98e-03	25	79	2	IPR006207
Domain	CTCK_2	MUC2 SSPOP	4.98e-03	25	79	2	PS01225
Domain	TNFR	CD40 TNFRSF10B	5.38e-03	26	79	2	SM00208
Domain	PHD	KMT2D JADE2 RAI1	6.37e-03	89	79	3	SM00249
Domain	TNFR_NGFR_1	CD40 TNFRSF10B	6.66e-03	29	79	2	PS00652
Domain	TNFR_NGFR_2	CD40 TNFRSF10B	6.66e-03	29	79	2	PS50050
Domain	Znf_PHD	KMT2D JADE2 RAI1	6.77e-03	91	79	3	IPR001965
Domain	ZF_PHD_2	KMT2D JADE2 RAI1	7.63e-03	95	79	3	PS50016
Domain	ZF_PHD_1	KMT2D JADE2 RAI1	7.85e-03	96	79	3	PS01359
Domain	FN3	FNDC7 KALRN EPHA2 PTPRU	7.86e-03	185	79	4	SM00060
Pubmed	G908R NOD2 variant in a family with sarcoidosis.	KALRN EPHA2 IL17RA	4.50e-08	4	79	3	29554915
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	JPH1 ERBB4 ARRDC4 POLR2C LRP2 TNFRSF10B RREB1 DHX34 LTBP4 DICER1 RAI1 HDAC1 HMG20B	1.32e-06	1116	79	13	31753913
Pubmed	Regulation of LSD1 histone demethylase activity by its associated factors.	RREB1 HDAC1 HMG20B	2.45e-06	12	79	3	16140033
Pubmed	Congenital Diaphragmatic Hernia Overview	KMT2D SMC3 LRP2 LTBP4	3.74e-06	46	79	4	20301533
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	RANBP2 FASN KMT2D RAPH1 LRP2 RREB1 HDAC1 HMG20B	5.04e-06	418	79	8	34709266
Pubmed	Fatty acid synthase modulates intestinal barrier function through palmitoylation of mucin 2.	FASN MUC2	5.09e-06	2	79	2	22341463
Pubmed	Mechanistic Roles of Matrilin-2 and Klotho in Modulating the Inflammatory Activity of Human Aortic Valve Cells.	KL MATN2	5.09e-06	2	79	2	32046115
Pubmed	Aldosterone induces renal fibrosis by promoting HDAC1 expression, deacetylating H3K9 and inhibiting klotho transcription.	KL HDAC1	5.09e-06	2	79	2	30592280
Pubmed	Somatic mutations of DICER1 and KMT2D are frequent in intraocular medulloepitheliomas.	KMT2D DICER1	5.09e-06	2	79	2	26841698
Pubmed	LTBP4, SPP1, and CD40 Variants: Genetic Modifiers of Duchenne Muscular Dystrophy Analyzed in Serbian Patients.	CD40 LTBP4	1.53e-05	3	79	2	36011296
Pubmed	Interaction network of human early embryonic transcription factors.	RANBP2 KMT2D ZNF521 RREB1 RAI1 HDAC1 HMG20B	1.56e-05	351	79	7	38297188
Pubmed	Evolution and cell-type specificity of human-specific genes preferentially expressed in progenitors of fetal neocortex.	NOTCH2NLA NOTCH2NLC	3.05e-05	4	79	2	29561261
Pubmed	Evolution of Human Brain Size-Associated NOTCH2NL Genes Proceeds toward Reduced Protein Levels.	NOTCH2NLA NOTCH2NLC	3.05e-05	4	79	2	32330268
Pubmed	The inositol Inpp5k 5-phosphatase affects osmoregulation through the vasopressin-aquaporin 2 pathway in the collecting system.	AVP LRP2	3.05e-05	4	79	2	21938401
Pubmed	Concerted activity of IgG1 antibodies and IL-4/IL-25-dependent effector cells trap helminth larvae in the tissues following vaccination with defined secreted antigens, providing sterile immunity to challenge infection.	CD40 IL17RA	3.05e-05	4	79	2	25816012
Pubmed	The stem cell-associated transcription co-factor, ZNF521, interacts with GLI1 and GLI2 and enhances the activity of the Sonic hedgehog pathway.	ZNF521 HDAC1	3.05e-05	4	79	2	31558698
Pubmed	Control of interneuron dendritic growth through NRG1/erbB4-mediated kalirin-7 disinhibition.	ERBB4 KALRN	3.05e-05	4	79	2	21483438
Pubmed	Human-Specific NOTCH2NL Genes Affect Notch Signaling and Cortical Neurogenesis.	NOTCH2NLA NOTCH2NLC	5.07e-05	5	79	2	29856954
Pubmed	Human-Specific NOTCH2NL Genes Expand Cortical Neurogenesis through Delta/Notch Regulation.	NOTCH2NLA NOTCH2NLC	5.07e-05	5	79	2	29856955
Pubmed	The functional interactome landscape of the human histone deacetylase family.	SMC3 ZNF521 RREB1 DICER1 HDAC1 HMG20B	5.22e-05	289	79	6	23752268
Pubmed	Genetic mapping of the human and mouse phospholipase C genes.	AVP CD40 PLCG2	5.86e-05	33	79	3	8672127
Pubmed	Genome-wide scan revealed that polymorphisms in the PNPLA3, SAMM50, and PARVB genes are associated with development and progression of nonalcoholic fatty liver disease in Japan.	PNPLA3 PTPRU	7.60e-05	6	79	2	23535911
Pubmed	Distinct Roles of HDAC3 in the Core Circadian Negative Feedback Loop Are Critical for Clock Function.	FBXL3 HDAC1	7.60e-05	6	79	2	26776516
Pubmed	Characterization of BHC80 in BRAF-HDAC complex, involved in neuron-specific gene repression.	HDAC1 HMG20B	7.60e-05	6	79	2	15325272
Pubmed	Large-scale proteomics and phosphoproteomics of urinary exosomes.	FASN EYS KL GLB1 KALRN DSG3 JADE2 LRP2 LAMA5 RREB1	1.01e-04	1016	79	10	19056867
Pubmed	Identification of multi-SH3 domain-containing protein interactome in pancreatic cancer: a yeast two-hybrid approach.	LIMD1 LAMA5 TTC1 LTBP4	1.03e-04	106	79	4	18654987
Pubmed	The SUMO E3 ligase RanBP2 promotes modification of the HDAC4 deacetylase.	RANBP2 HDAC1	1.06e-04	7	79	2	12032081
Pubmed	A core-BRAF35 complex containing histone deacetylase mediates repression of neuronal-specific genes.	HDAC1 HMG20B	1.06e-04	7	79	2	12032298
Pubmed	A genome-wide search for quantitative trait loci affecting the cortical surface area and thickness of Heschl's gyrus.	GCNT7 KALRN IL17RA	1.30e-04	43	79	3	25130324
Pubmed	Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes.	RREB1 HDAC1 HMG20B	1.49e-04	45	79	3	21258344
Pubmed	The role of WDR5 in silencing human fetal globin gene expression.	KMT2D HDAC1	1.82e-04	9	79	2	22689669
Pubmed	Location of the 9257 and ataxia mutations on mouse chromosome 18.	DSG3 ZNF521	1.82e-04	9	79	2	8662222
Pubmed	An ACT1 mutation selectively abolishes interleukin-17 responses in humans with chronic mucocutaneous candidiasis.	CD40 IL17RA	2.27e-04	10	79	2	24120361
Pubmed	Gene structure and chromosomal localization of the mouse homologue of rat OX40 protein.	EPHA2 CD40	2.27e-04	10	79	2	7737295
Pubmed	Proteomic analysis of DZIP3 interactome and its role in proliferation and metastasis in gastric cancer cells.	LIMD1 SMC3 HDAC1	2.43e-04	53	79	3	36841324
Pubmed	Spindle Assembly Checkpoint Inhibition Can Resensitize p53-Null Stem Cells to Cancer Chemotherapy.	KMT2D NKAIN4 DCAF10 POLR2C	2.75e-04	137	79	4	30862715
Pubmed	Requirement of tumor necrosis factor receptor-associated factor (TRAF)6 in interleukin 17 signal transduction.	CD40 IL17RA	2.76e-04	11	79	2	10748240
Pubmed	The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.	RANBP2 FASN RAPH1 EPHA2 MYPN	3.00e-04	256	79	5	33397691
Pubmed	Many Th Cell Subsets Have Fas Ligand-Dependent Cytotoxic Potential.	CD40 TNFRSF10B	3.31e-04	12	79	2	29436413
Pubmed	UM171 Preserves Epigenetic Marks that Are Reduced in Ex Vivo Culture of Human HSCs via Potentiation of the CLR3-KBTBD4 Complex.	RANBP2 FASN LIMD1 SMC3 TTC1	3.64e-04	267	79	5	33417871
Pubmed	Histone demethylase JMJD2B coordinates H3K4/H3K9 methylation and promotes hormonally responsive breast carcinogenesis.	KMT2D HDAC1	3.91e-04	13	79	2	21502505
Pubmed	An essential role for CoREST in nucleosomal histone 3 lysine 4 demethylation.	HDAC1 HMG20B	3.91e-04	13	79	2	16079794
Pubmed	Functional proteomics mapping of a human signaling pathway.	TSKU KMT2D LIMD1 AP1G1 SUSD1 LAMA5 PLCG2	3.98e-04	591	79	7	15231748
Pubmed	Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.	MATN2 LAMA5 MUC2 LTBP4	4.19e-04	153	79	4	25037231
Pubmed	Endothelial Jarid2/Jumonji is required for normal cardiac development and proper Notch1 expression.	ERBB4 NOTCH4	4.55e-04	14	79	2	21402699
Pubmed	Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy.	FMO2 EPHA2 ALDH4A1	4.66e-04	66	79	3	19898482
Pubmed	Global analysis of host-pathogen interactions that regulate early-stage HIV-1 replication.	RANBP2 POLR2C PTPRU RREB1 HDAC1	4.75e-04	283	79	5	18854154
Pubmed	Identifying leukocyte gene expression patterns associated with plasma lipid levels in human subjects.	FASN TPRA1 CD40	4.87e-04	67	79	3	16806233
Pubmed	Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.	FASN GLB1 SUSD1 SMC3 LAMA5 LTBP4 FBXL3	4.94e-04	613	79	7	22268729
Pubmed	Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis.	MUC2 NOTCH4	5.25e-04	15	79	2	23583980
Pubmed	TRIM28 functions as the SUMO E3 ligase for PCNA in prevention of transcription induced DNA breaks.	RANBP2 POLR2C	5.25e-04	15	79	2	32900933
Pubmed	The BRCT-domain containing protein PTIP links PAX2 to a histone H3, lysine 4 methyltransferase complex.	KMT2D SMC3	5.25e-04	15	79	2	17925232
Pubmed	Coordinated histone modifications mediated by a CtBP co-repressor complex.	RREB1 HDAC1	5.25e-04	15	79	2	12700765
Pubmed	The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.	MATN2 LAMA5 MUC2 LTBP4	5.82e-04	167	79	4	22159717
Pubmed	Chfr is linked to tumour metastasis through the downregulation of HDAC1.	RANBP2 HDAC1	5.99e-04	16	79	2	19182791
Pubmed	Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.	MATN2 LAMA5 LTBP4 SSPOP	6.94e-04	175	79	4	28071719
Pubmed	DNA damage shifts circadian clock time via Hausp-dependent Cry1 stabilization.	RANBP2 FASN DICER1 FBXL3	6.94e-04	175	79	4	25756610
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	RANBP2 LIMD1 RAPH1 LRP2 CCT6B TTC1 LTBP4 RGS12	7.12e-04	853	79	8	28718761
Pubmed	SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.	RANBP2 FASN DCAF10 RNF113A DICER1 HDAC1 HMG20B	7.30e-04	655	79	7	35819319
Pubmed	USP10 deubiquitinates Tau, mediating its aggregation.	JADE2 LAMA5	7.61e-04	18	79	2	35987808
Pubmed	A candidate X-linked mental retardation gene is a component of a new family of histone deacetylase-containing complexes.	HDAC1 HMG20B	7.61e-04	18	79	2	12493763
Pubmed	Conserved Mitotic Phosphorylation of a Proteasome Subunit Regulates Cell Proliferation.	SMC3 POLR2C HDAC1	8.17e-04	80	79	3	34831298
Pubmed	The regulation of HIV-1 transcription: molecular targets for chemotherapeutic intervention.	POLR2C HDAC1	8.50e-04	19	79	2	16838299
Pubmed	Daxx Inhibits HIV-1 Reverse Transcription and Uncoating in a SUMO-Dependent Manner.	RANBP2 HDAC1	8.50e-04	19	79	2	32545337
Pubmed	Transcriptional fates of human-specific segmental duplications in brain.	NOTCH2NLA NOTCH2NLC	8.50e-04	19	79	2	30228200
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	RANBP2 FASN KMT2D SMC3 RNF113A RREB1 RAI1 HDAC1 HMG20B	8.85e-04	1103	79	9	34189442
Pubmed	HIV-1 Tat and host AFF4 recruit two transcription elongation factors into a bifunctional complex for coordinated activation of HIV-1 transcription.	POLR2C HDAC1	9.43e-04	20	79	2	20471948
Pubmed	FBXW7 Triggers Degradation of KMT2D to Favor Growth of Diffuse Large B-cell Lymphoma Cells.	KMT2D FBXL3	9.43e-04	20	79	2	32350066
Pubmed	The transcriptional repressor Blimp1/Prdm1 regulates postnatal reprogramming of intestinal enterocytes.	GLB1 MUC2	1.04e-03	21	79	2	21670299
Pubmed	Genetic loci controlling body fat, lipoprotein metabolism, and insulin levels in a multifactorial mouse model.	CD40 LRP2	1.04e-03	21	79	2	9616220
Pubmed	Hdac1 and Hdac2 act redundantly to control p63 and p53 functions in epidermal progenitor cells.	FASN HDAC1	1.04e-03	21	79	2	21093383
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	RANBP2 FASN GLB1 AP1G1 SMC3 DMAC2 ALDH4A1	1.11e-03	704	79	7	29955894
Pubmed	SUMOylation of DDX39A Alters Binding and Export of Antiviral Transcripts to Control Innate Immunity.	RANBP2 FNDC7 JADE2 POLR2C DMAC2 KCNMB4 ZXDB AFG1L	1.12e-03	915	79	8	32393512
Pubmed	Identification of single nucleotide polymorphisms in the tumor necrosis factor (TNF) and TNF receptor superfamily in the Korean population.	CD40 TNFRSF10B	1.14e-03	22	79	2	15301860
Pubmed	Morphogenesis in skin is governed by discrete sets of differentially expressed microRNAs.	LAMA5 DICER1	1.14e-03	22	79	2	16462742
Pubmed	Constitutive activation of hedgehog signaling adversely affects epithelial cell fate during palatal fusion.	DSG3 LAMA5	1.25e-03	23	79	2	29981310
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CAMKK2 JADE2 LAMA5 DHX34 DICER1 RAI1	1.31e-03	529	79	6	14621295
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	LIMD1 EPHA2 MYPN DICER1	1.34e-03	209	79	4	36779422
Pubmed	A general approach for investigating enzymatic pathways and substrates for ubiquitin-like modifiers.	RANBP2 KALRN	1.36e-03	24	79	2	16620772
Pubmed	Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.	TPRA1 CAMKK2 GLB1 DICER1 ZNHIT3 FBXL3	1.40e-03	536	79	6	15840001
Pubmed	Affinity purification strategies for proteomic analysis of transcription factor complexes.	SMC3 POLR2C HDAC1	1.43e-03	97	79	3	23937658
Pubmed	Exchangeable gene trap using the Cre/mutated lox system.	TPRA1 CAMKK2 GLB1 DICER1 ZNHIT3 FBXL3	1.43e-03	538	79	6	10512203
Pubmed	Identification of tyrosine kinases expressed in the male mouse gubernaculum during development.	ERBB4 EPHA2	1.48e-03	25	79	2	15254900
Pubmed	Holoprosencephaly Overview	KMT2D SMC3	1.48e-03	25	79	2	20301702
Pubmed	BioID Performed on Golgi Enriched Fractions Identify C10orf76 as a GBF1 Binding Protein Essential for Golgi Maintenance and Secretion.	RANBP2 FASN RAPH1 MYPN	1.51e-03	216	79	4	31519766
Pubmed	TFAM is required for maturation of the fetal and adult intestinal epithelium.	GUCA2A MUC2	1.60e-03	26	79	2	29684311
Pubmed	Proteomics characterization of extracellular space components in the human aorta.	MATN2 LAMA5 LTBP4	1.60e-03	101	79	3	20551380
Pubmed	Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition.	ERBB4 CAMKK2 EPHA2 PRKG2 FBXL3	1.61e-03	372	79	5	22939624
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	RANBP2 FASN SMC3 EPHA2 CCT6B ANKMY2 PTPRU DICER1	1.66e-03	974	79	8	28675297
Pubmed	Loss of Cubilin, the intrinsic factor-vitamin B12 receptor, impairs visceral endoderm endocytosis and endodermal patterning in the mouse.	AP1G1 LRP2	1.72e-03	27	79	2	31308417
Pubmed	Intestinal NCoR1, a regulator of epithelial cell maturation, controls neonatal hyperbilirubinemia.	GLB1 LRP2	1.72e-03	27	79	2	28167773
Pubmed	Genetic link between renal birth defects and congenital heart disease.	LRP2 LAMA5	1.85e-03	28	79	2	27002738
Pubmed	High glucose mediates the ChREBP/p300 transcriptional complex to activate proapoptotic genes Puma and BAX and contributes to intervertebral disc degeneration.	FASN PNPLA3	1.99e-03	29	79	2	34461288
Pubmed	The Catalytically Inactive Mutation of the Ubiquitin-Conjugating Enzyme CDC34 Affects its Stability and Cell Proliferation.	RANBP2 FASN SMC3 HDAC1	2.12e-03	237	79	4	29564676
Pubmed	Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex.	RANBP2 FASN SMC3 EPHA2 HDAC1	2.18e-03	399	79	5	37536630
Coexpression	NABA_ECM_GLYCOPROTEINS	TSKU EYS FNDC7 MATN2 LAMA5 LTBP4 SSPOP FBN3	1.27e-07	196	78	8	M3008
Coexpression	NABA_CORE_MATRISOME	TSKU EYS FNDC7 MATN2 LAMA5 LTBP4 SSPOP FBN3	1.65e-06	275	78	8	M5884
Coexpression	NABA_ECM_GLYCOPROTEINS	TSKU FNDC7 MATN2 LAMA5 LTBP4 SSPOP	2.30e-05	191	78	6	MM17059
Coexpression	GSE23308_CTRL_VS_CORTICOSTERONE_TREATED_MACROPHAGE_MINERALCORTICOID_REC_KO_UP	GLB1 DMAC2 ALDH4A1 RREB1 HMG20B AFG1L	2.98e-05	200	78	6	M7746
ToppCell	Transverse-Macrophage-LYVE1_Macrophage\|Macrophage / Region, Cell class and subclass	KL RAPH1 MAMDC2 ERCC6L2 ABCA9 FBXL3	1.48e-06	199	79	6	fd75dccb37d96448edf72b7d042b06833d4ead24
ToppCell	facs-Large_Intestine-Distal-18m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CAMKK2 KALRN PNPLA3 PLCG2 ADAM22	1.50e-05	175	79	5	f24b664b9056b5976bf2222e8013f15c09e049ad
ToppCell	PCW_05-06-Endothelial-Endothelial_mature-endo_arterial_(9)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	EYS KL CD40 PLCG2 NOTCH4	1.72e-05	180	79	5	5861b44acfb8fe92c281c8355bf19c059b3dcd64
ToppCell	droplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NKAIN4 MAMDC2 LRP2 LTBP4 ABCA9	2.07e-05	187	79	5	4e553721fa5598cb211f44e3226280b7e6885484
ToppCell	droplet-Pancreas-Exocrine-18m-Mesenchymal\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NKAIN4 MAMDC2 LRP2 LTBP4 ABCA9	2.07e-05	187	79	5	d36e7fc6125e7a4310499365022d38f34b757a73
ToppCell	droplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NKAIN4 MAMDC2 LRP2 LTBP4 ABCA9	2.07e-05	187	79	5	827eae63fabf6892a82ce7779b5f395958d3d628
ToppCell	E16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal\|E16.5-samps / Age Group, Lineage, Cell class and subclass	FMO2 NKAIN4 CD40 PRKG2 LTBP4	2.29e-05	191	79	5	3379d145d34f89150f7b06d1340022cfc6b4a6ce
ToppCell	PCW_05-06-Endothelial-Endothelial_immature-endo_immature_arterial2_(6)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	EYS KL CD40 PLCG2 NOTCH4	2.29e-05	191	79	5	e3fc5c92491b6e334abffbf085c00a0b5fa1aed2
ToppCell	COVID-19-kidney-VWF+PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	KALRN ZNF521 KCNMB4 PLCG2 NOTCH4	2.29e-05	191	79	5	2f00d0b7b2ffce8eb3eb5bbae49a0d425b23c982
ToppCell	Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|World / Lineage, Cell type, age group and donor	JPH1 ERBB4 LAMA5 PRKG2 FBN3	2.29e-05	191	79	5	d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCell	LA\|World / Chamber and Cluster_Paper	FASN MAMDC2 LRP2 PNPLA3 ABCA9	2.40e-05	193	79	5	d4bf89437216baf489ea0239136dcedf3b6714af
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FMO2 KALRN MATN2 LTBP4 ABCA9	2.52e-05	195	79	5	cad6563cc51d212554152c727fc2c249c6a07e4d
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FMO2 KALRN MATN2 LTBP4 ABCA9	2.52e-05	195	79	5	783bfa8110161cbd6def50ce849cae676c39c458
ToppCell	E17.5-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FMO2 NKAIN4 MATN2 CD40 PRKG2	2.52e-05	195	79	5	b072fdc2131173f562e55dd78226eaf2c57d3690
ToppCell	Caecum-T_cell-Tfh\|T_cell / Region, Cell class and subclass	RAPH1 KCNMB4 DNAH9 ABCA9 ZXDB	2.59e-05	196	79	5	fe2ee5788028e6b671674f0cc50e2b6379f50976
ToppCell	367C-Epithelial_cells-Epithelial-H_(AT1)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	TSKU ALDH4A1 TNFRSF10B LTBP4 RGS12	2.59e-05	196	79	5	e8db58e82300981f981402618a1befb91f6690fd
ToppCell	367C-Epithelial_cells-Epithelial-H_(AT1)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	TSKU ALDH4A1 TNFRSF10B LTBP4 RGS12	2.59e-05	196	79	5	2cf42b702ea15adfa6bbd86a3c9613271863f86c
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FMO2 KALRN MATN2 LTBP4 ABCA9	2.65e-05	197	79	5	09946ee8dfb15a2a32da06e5b331f3277ee934f4
ToppCell	proximal-mesenchymal-Adventitial_Fibroblast\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FMO2 MAMDC2 MATN2 LTBP4 ABCA9	2.85e-05	200	79	5	58c5870030192b337e7d883044948634fcd17d2c
ToppCell	Biopsy_IPF-Epithelial-Basal\|Biopsy_IPF / Sample group, Lineage and Cell type	TSKU FMO2 DSG3 LAMA5 LTBP4	2.85e-05	200	79	5	5cea84581201cee7ba8141b96e65864f4fd67113
ToppCell	proximal-mesenchymal-Adventitial_Fibroblast-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FMO2 MAMDC2 MATN2 LTBP4 ABCA9	2.85e-05	200	79	5	05486d86868f6a93429226063cca270f00dd8714
ToppCell	proximal-3-mesenchymal-Adventitial_Fibroblast\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FMO2 MAMDC2 MATN2 LTBP4 ABCA9	2.85e-05	200	79	5	869d45b71efd395d050873db5fee2ed0443d5e6f
ToppCell	Parenchymal-10x3prime_v2-Stromal-Fibroblastic-Fibro_peribronchial\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	FMO2 MAMDC2 MATN2 LTBP4 ABCA9	2.85e-05	200	79	5	efdf7066b7dd43e35dbc0d2719b75f250cf54af2
ToppCell	normal_Lung-Fibroblasts-COL14A1+_matrix_FBs\|normal_Lung / Location, Cell class and cell subclass	TSKU FMO2 MATN2 LTBP4 ABCA9	2.85e-05	200	79	5	ee3d06865a6300e1279edf6664320b71647f5efb
ToppCell	Control-Endothelial-Endothelial-Activated_Gen_Cap\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	AVP EPHA2 TNFRSF10B NOTCH4	6.40e-05	121	79	4	a5962d1c476e6966870832b72d511607e047248b
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DSG3 PLCG2 FBN3 OR2H2	1.13e-04	140	79	4	e64f6aa57bc069cfe970089bd1c298433bfaf771
ToppCell	metastatic_Lymph_Node-Myeloid_cells-Alveolar_Mac\|Myeloid_cells / Location, Cell class and cell subclass	BCL2L15 DSG3 ARRDC4 DNAH9	1.16e-04	141	79	4	399380de5ea09e22fd128e3e55fffeffc4874c15
ToppCell	10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_granulocytic-basophil\|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	AVP MAMDC2 ZNF521 PRKG2	1.47e-04	150	79	4	408b7c2c3a42f5455c8c26a83d9e366a1c8d5ecc
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_bronchial_vessel-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	KL KALRN CD40 NOTCH4	1.71e-04	156	79	4	ff39712c7a2dc1b85c598d5105789aa291dea726
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	JPH1 ERBB4 LAMA5 PRKG2	1.84e-04	159	79	4	8680b054622f573a82b1625fb93c2d5db81d1034
ToppCell	severe_influenza-cDC\|World / disease group, cell group and cell class (v2)	EPHA2 ZNF521 PRKG2 RGS12	1.93e-04	161	79	4	802f8cafb5f499e3b2ec0193d6eb1ac9320b9287
ToppCell	severe_influenza-cDC\|severe_influenza / disease group, cell group and cell class (v2)	EPHA2 ZNF521 PRKG2 RGS12	1.93e-04	161	79	4	7716315b8bda904b346cea47edc2c0b507a345c2
ToppCell	10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_dendritic\|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	AVP ZNF521 PRKG2 MUC2	1.97e-04	162	79	4	233011408f022647932c81ebab78f9813e3c6833
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell_prolif\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FMO2 MATN2 LTBP4 NOTCH4	2.02e-04	163	79	4	1feb4ef7b8abcfca9a72c8d13c40548de79e7db2
ToppCell	IIF-Other-HSPC\|IIF / Disease, Lineage and Cell Type	TSKU AVP MAMDC2 ZNF521	2.02e-04	163	79	4	1e0d38fbed38ac48478868a1480172a1a3f7c1b7
ToppCell	Influenza_Severe-cDC\|World / Disease group and Cell class	EPHA2 ZNF521 PRKG2 RGS12	2.07e-04	164	79	4	c984228f73b9aa1aaf948541f64f41ed874770cd
ToppCell	Multiple_Sclerosis-Other-HSPC\|Multiple_Sclerosis / Disease, Lineage and Cell Type	AVP MAMDC2 ZNF521 PRKG2	2.07e-04	164	79	4	6af5529507d695b347adee4be5ead70f56c9cf55
ToppCell	Influenza_Severe-cDC\|Influenza_Severe / Disease group and Cell class	EPHA2 ZNF521 PRKG2 RGS12	2.16e-04	166	79	4	b40bdf0f7f381e25be61188e9f6c294d25a8b824
ToppCell	facs-Lung-24m-Hematologic-myeloid-interstitial_macrophage-interstitial_macrophage_l12\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SAP25 MATN2 ABCA9 ADAM22	2.16e-04	166	79	4	7be2b5c62e2be3437ea50b9a473cf9fc7f05e0b1
ToppCell	facs-Lung-24m-Hematologic-myeloid-interstitial_macrophage\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SAP25 MATN2 ABCA9 ADAM22	2.16e-04	166	79	4	8418b191e7f16cb39301df3ddbfb1bab6c0632d6
ToppCell	Adult-Endothelial-endothelial_cell_of_vein-D175\|Adult / Lineage, Cell type, age group and donor	GCNT7 KALRN ZNF521 KCNMB4	2.32e-04	169	79	4	e1f0298236e4a1c59077c14f0dd29a78fac12648
ToppCell	facs-Marrow-KLS-3m-Hematologic-Unknown_Progenitor\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FNDC7 MATN2 KCNMB4 SSPOP	2.32e-04	169	79	4	b798b91567d2f49082e2d8a337169f241c8d2080
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FMO2 MAMDC2 MATN2 ABCA9	2.42e-04	171	79	4	15cb4670ff4234ac46aea8a5911138d6913c4482
ToppCell	COVID-pDC\|COVID / Condition, Cell_class and T cell subcluster	SUSD1 EPHA2 ZNF521 NOTCH4	2.48e-04	172	79	4	3ecbb000495dde32f6153ef6bdea9c8802ff3985
ToppCell	(07)_Ionocytes-(2)_GFP_FOXI1\|(07)_Ionocytes / shred by cell type by condition	FASN SMC3 EPHA2 NOTCH2NLA	2.48e-04	172	79	4	5776b638b845d054f6e884e7df0412477f48517d
ToppCell	COVID-pDC-\|COVID / Condition, Cell_class and T cell subcluster	SUSD1 EPHA2 ZNF521 NOTCH4	2.48e-04	172	79	4	a7827faa1afab51fdaf0cb1a2babcd2e00d411e5
ToppCell	facs-Large_Intestine-Distal-24m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CAMKK2 KALRN PNPLA3 PLCG2	2.53e-04	173	79	4	f0eb48c1283bdde313bb75f6ffc0d2626922d24b
ToppCell	TCGA-Breast-Solid_Tissue_Normal-Breast_normal_tissue-Breast_normal_tissue-3\|TCGA-Breast / Sample_Type by Project: Shred V9	KL FMO2 MAMDC2 ABCA9	2.59e-04	174	79	4	7f8f5fafae08676d2b90cab9802c3c9320f1370e
ToppCell	severe_COVID-19-HSPC\|severe_COVID-19 / disease group, cell group and cell class (v2)	AVP MAMDC2 ZNF521 PRKG2	2.59e-04	174	79	4	6d35bacf073537b272ff821e604c899fb9ce6a7c
ToppCell	368C-Endothelial_cells-Endothelial-D\|368C / Donor, Lineage, Cell class and subclass (all cells)	LAMA5 PLCG2 PRKG2 NOTCH4	2.65e-04	175	79	4	c4088b5f9fa145869cf5dd8bee7680b1c8fada42
ToppCell	368C-Endothelial_cells-Endothelial-D-\|368C / Donor, Lineage, Cell class and subclass (all cells)	LAMA5 PLCG2 PRKG2 NOTCH4	2.65e-04	175	79	4	ca0d3e3a0a271cccdd3881b055fecb626712478d
ToppCell	Adult-Endothelial-endothelial_cell_of_bronchial_vessel-D175\|Adult / Lineage, Cell type, age group and donor	KL KALRN ZNF521 NOTCH4	2.76e-04	177	79	4	c9f269765c7d5d29caab75910e51645606ed562e
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SUSD1 PLCG2 ADAM22 FBN3	2.76e-04	177	79	4	f35b04c3557ebbdeba37dec54c8f45880eafb422
ToppCell	ILEUM-inflamed-(9)_Enteric_neurons\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	MAMDC2 MATN2 KCNMB4 ABCA9	2.82e-04	178	79	4	d9142151819afb0dc22bfb32a9c9dba5f553067d
ToppCell	ILEUM-inflamed-(9)_Neuro_cell\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	MAMDC2 MATN2 KCNMB4 ABCA9	2.82e-04	178	79	4	611504b0a9e6318b18fba83787b03f9245c82252
ToppCell	PCW_13-14-Endothelial-Endothelial_mature-endo_arterial_(9)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	EYS KL PLCG2 NOTCH4	2.82e-04	178	79	4	c227da59dc7beb73f84405bf13356bdeb59d9338
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	EPHA2 PNPLA3 PLCG2 RAI1	2.88e-04	179	79	4	6e965e424eebef50f0202cff75f458be395cfca1
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	JPH1 ERBB4 LAMA5 PRKG2	2.88e-04	179	79	4	cb38b54261a7af5ee3347e64c8aa880a77ed0763
ToppCell	-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	FMO2 MAMDC2 LTBP4 ABCA9	2.88e-04	179	79	4	10fadbaa1b6d21cbf9f354d717cc4c225619f4fd
ToppCell	ASK452-Immune-B_cell\|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq	MATN2 ZNF521 PTPRU DNAH9	2.88e-04	179	79	4	c3cf49c069e66db16d2fce1de4c52a4c4fe7e832
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FMO2 KALRN ZNF521 NOTCH4	2.88e-04	179	79	4	8f9e538c822940785130297712b75131812a4603
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MAMDC2 MATN2 LTBP4 ADAM22	2.88e-04	179	79	4	02c90d8306016365ed811f0c63cfb3ac7b85464c
ToppCell	severe-Others-CD34+_GATA2+_cells\|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	AVP MAMDC2 ZNF521 PRKG2	2.88e-04	179	79	4	dd789a1b7327d6f9ed5272f3eb54bd43f7ae8d78
ToppCell	LA-01._Fibroblast_I\|LA / Chamber and Cluster_Paper	FMO2 MAMDC2 LTBP4 ABCA9	2.88e-04	179	79	4	dcb6ec9ae72b13fe388b72dace2815293fafe8ee
ToppCell	droplet-Kidney-nan-3m-Epithelial-kidney_proximal_straight_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KL FMO2 LRP2 ALDH4A1	2.95e-04	180	79	4	b34d933cdabf692f02eaaf65c2aaca1fb9510627
ToppCell	COVID-19-kidney-PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	KALRN KCNMB4 PLCG2 NOTCH4	2.95e-04	180	79	4	493cf8d1a8f2a1ed2672f394a0338b110fd81d88
ToppCell	MatrixFB-Fibroblast-A\|MatrixFB / shred on cell class and cell subclass (v4)	FMO2 LIMD1 CD40 PRKG2	2.95e-04	180	79	4	adc64ad6033af705dd7b9163a83e20ef5c59f6eb
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FMO2 NKAIN4 LRP2 ZNF521	3.01e-04	181	79	4	330d4322f4c4373f706273c1f4e218b59051b7fd
ToppCell	COVID-19-Endothelial_cells-Endothelial_cells_(other)\|COVID-19 / group, cell type (main and fine annotations)	KALRN LAMA5 KCNMB4 NOTCH4	3.01e-04	181	79	4	26eb4ee57a70dbf54e096b73129fda9dfda1f6ec
ToppCell	COVID-19-Endothelial_cells-Capillary_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	KALRN LAMA5 HERC3 NOTCH4	3.01e-04	181	79	4	c5f9c92af1384d9089c65afdf41c6feb8345a3ae
ToppCell	P28-Mesenchymal-mesenchymal_fibroblast\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FMO2 MAMDC2 PRKG2 LTBP4	3.01e-04	181	79	4	091e7975badd1ffa463a8ec87908be20781ecfd6
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FMO2 NKAIN4 LRP2 ZNF521	3.01e-04	181	79	4	3f4d5d79c1286614514b0e8134079d6128a2a23e
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Macroglial-Schwann_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NKAIN4 MAMDC2 MATN2 KCNMB4	3.07e-04	182	79	4	d568a8aec7e27ce632e248baea2ccd0e8dd255ac
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAMDC2 MATN2 LTBP4 ABCA9	3.07e-04	182	79	4	3dfa9187e9d2bab1d199079d29209c4648220ada
ToppCell	P28-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FMO2 MAMDC2 PRKG2 LTBP4	3.07e-04	182	79	4	19c5e3a9d9b3728303b682102e276adfe93aa759
ToppCell	(00)_Basal-(0)_uninjured\|(00)_Basal / shred by cell type and Timepoint	FMO2 ARRDC4 PTPRU LTBP4	3.07e-04	182	79	4	c02c9cab4389d80f318f4bb8d703c1e719672624
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	JPH1 ERBB4 FMO2 EPHA2	3.07e-04	182	79	4	215c303df42f13597b2c7a95cb157c6bc7aca9a1
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Macroglial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NKAIN4 MAMDC2 MATN2 KCNMB4	3.07e-04	182	79	4	e89cc30db8e5c77a8bbddd1d5a4b5af09f1ccd67
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Macroglial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NKAIN4 MAMDC2 MATN2 KCNMB4	3.07e-04	182	79	4	82ca6d5ed48b4c487ce00b9309255abb8f20b61d
ToppCell	P07-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FMO2 MAMDC2 MATN2 LTBP4	3.20e-04	184	79	4	01257e5c12e38b849fd3d9496c43ded666249ba5
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KALRN LRP2 SSPOP DNAH9	3.20e-04	184	79	4	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	PBMC-Severe-Hematopoietic-HSPC\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	AVP MAMDC2 ZNF521 PRKG2	3.20e-04	184	79	4	a6169613c6493b947a176493f542368bfa935dab
ToppCell	PBMC-Severe-Hematopoietic-HSPC-HSPC\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	AVP MAMDC2 ZNF521 PRKG2	3.20e-04	184	79	4	51d0447699e3b8f01abbde83f26b748bc9f3c723
ToppCell	droplet-Lung-nan-3m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMO2 MAMDC2 PRKG2 LTBP4	3.20e-04	184	79	4	89ac32e374a4379e4a6c6ea7603b1378b77c147f
ToppCell	P28-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FMO2 MAMDC2 PRKG2 LTBP4	3.20e-04	184	79	4	924400f47e6b2cdf7b0d538df75857935cf0209b
ToppCell	droplet-Kidney-nan-18m\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KL FMO2 LRP2 ALDH4A1	3.20e-04	184	79	4	e02859bbac36dbbd55d7ae8cb5e46b764d7c6381
ToppCell	PCW_10-12-Endothelial-Endothelial_mature-endo_arterial_(9)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	EYS KL PLCG2 NOTCH4	3.20e-04	184	79	4	a809b0fa52df8a159f60f87eefcef61220af5e34
ToppCell	PBMC-Severe-Hematopoietic-HSPC-HSPC-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	AVP MAMDC2 ZNF521 PRKG2	3.20e-04	184	79	4	f7b0bb45a9055ab34e98b251217f6ec38c75ca22
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell-D122\|Adult / Lineage, Cell type, age group and donor	MAMDC2 ZNF521 LTBP4 ABCA9	3.20e-04	184	79	4	2b7e6f91e11c228f0521e099886867d9e998e78d
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KALRN LRP2 SSPOP DNAH9	3.20e-04	184	79	4	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KALRN LRP2 SSPOP DNAH9	3.20e-04	184	79	4	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	droplet-Lung-nan-3m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMO2 MAMDC2 PRKG2 LTBP4	3.20e-04	184	79	4	4df6027fa635996c1eddb920f88a5265772df1cd
ToppCell	PBMC-Severe-Hematopoietic-HSPC-HSPC\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	AVP MAMDC2 ZNF521 PRKG2	3.20e-04	184	79	4	cc01c19180861f491a8dc16d60fabd1215fc4525
ToppCell	PBMC-Severe-Hematopoietic-HSPC-HSPC-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	AVP MAMDC2 ZNF521 PRKG2	3.20e-04	184	79	4	492c680f0769ba4e651d09c2e8e5d5d271ed08aa
ToppCell	PBMC-Severe-Hematopoietic-HSPC\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	AVP MAMDC2 ZNF521 PRKG2	3.20e-04	184	79	4	26edbf84216538b80f1ffcc079ee6e385a71fbf9
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MAMDC2 MATN2 LTBP4 ADAM22	3.27e-04	185	79	4	6712512100ccef456d2e2bd201d0987986c92ac9
ToppCell	droplet-Kidney-KIDNEY-1m-Mesenchymal-podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NKAIN4 EPHA2 MATN2 ZNF521	3.27e-04	185	79	4	ca69499ba8c39b7ed6717d05685d6f70066a77bd
ToppCell	droplet-Kidney-nan-3m-Epithelial-Epcam____kidney_proximal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KL FMO2 LRP2 ALDH4A1	3.27e-04	185	79	4	3e3217c99719fd1d2fa94e16be7712a7e5077152
ToppCell	droplet-Kidney-nan-3m-Epithelial-kidney_proximal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KL FMO2 LRP2 ALDH4A1	3.27e-04	185	79	4	0ff4148b4701003d9d594e0da8261176fb13aa59
ToppCell	COVID-19-kidney-FLT1+PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	KALRN KCNMB4 PLCG2 NOTCH4	3.27e-04	185	79	4	673308ca0514a4d3629d61fe91e9d8fb31b72166
Drug	Lithocholic acid [434-13-9]; Up 200; 10.6uM; MCF7; HT_HG-U133A	CAMKK2 INSL4 MUC2 DHX34 LTBP4 DICER1 ADAM22 RGS12	3.81e-07	197	78	8	3899_UP
Drug	Flunisolide [3385-03-3]; Up 200; 9.2uM; PC3; HT_HG-U133A	FASN KL CAMKK2 KALRN JADE2 PTPRU DHX34	4.33e-06	192	78	7	4303_UP
Drug	1xqc	TSKU PLCG2 FBN3	6.26e-06	11	78	3	CID005287617
Drug	Mukaiyama's reagent	TSKU GLB1	1.16e-05	2	78	2	CID000171631
Drug	Bordeaux red	TSKU DSG3	1.16e-05	2	78	2	CID005351791
Disease	beta-nerve growth factor measurement	FASN NOTCH4 AFG1L	1.82e-04	42	77	3	EFO_0008035
Disease	hematocrit	RAPH1 SUSD1 KALRN JADE2 LRP2 PNPLA3 RREB1 LTBP4 NOTCH4 RAI1	2.92e-04	1011	77	10	EFO_0004348
Disease	Schizophrenia	ERBB4 CAMKK2 AVP LRP2 DICER1 RGS12 NOTCH4 RAI1 HDAC1	4.83e-04	883	77	9	C0036341
Disease	xanthine measurement	EYS ADAM22	5.15e-04	13	77	2	EFO_0010548
Disease	homostachydrine measurement	EYS ERBB4	5.15e-04	13	77	2	EFO_0021164
Disease	colitis (implicated_via_orthology)	CD40 MUC2	5.15e-04	13	77	2	DOID:0060180 (implicated_via_orthology)
Disease	membranous glomerulonephritis (biomarker_via_orthology)	LRP2 PTPRU	5.99e-04	14	77	2	DOID:10976 (biomarker_via_orthology)
Disease	acute graft vs. host disease, donor genotype effect measurement	EYS KALRN	6.90e-04	15	77	2	EFO_0004599, EFO_0007892
Disease	neuroticism measurement, cognitive function measurement	ERBB4 KALRN JADE2 PTPRU ZNHIT3 RAI1 AFG1L	6.95e-04	566	77	7	EFO_0007660, EFO_0008354
Disease	perinatal necrotizing enterocolitis (biomarker_via_orthology)	CD40 MUC2	8.91e-04	17	77	2	DOID:8677 (biomarker_via_orthology)
Disease	thyroid peroxidase antibody measurement	KALRN ERCC6L2 DICER1	8.95e-04	72	77	3	EFO_0005666
Disease	C-C motif chemokine 3 measurement	PLCG2 ZNHIT3	1.00e-03	18	77	2	EFO_0008051
Disease	Intellectual Disability	FASN RNF113A LRP2 ALDH4A1 FBXL3 RAI1	1.12e-03	447	77	6	C3714756
Disease	hepatocellular carcinoma (is_implicated_in)	ERBB4 SMC3 PNPLA3 DICER1	1.31e-03	181	77	4	DOID:684 (is_implicated_in)
Disease	coffee consumption measurement	EYS JADE2 MYPN RAI1	1.33e-03	182	77	4	EFO_0006781
Disease	saturated fatty acids to total fatty acids percentage	PNPLA3 NOTCH4	1.37e-03	21	77	2	EFO_0022305
Disease	nose morphology measurement, mouth morphology measurement	CD40 FBN3	1.37e-03	21	77	2	EFO_0007843, EFO_0007955
Disease	nephrosis (biomarker_via_orthology)	LRP2 PTPRU	1.50e-03	22	77	2	DOID:2527 (biomarker_via_orthology)
Disease	body weight	FASN EYS ERBB4 SUSD1 JADE2 ZNF521 PRKG2 TTC1 ZNHIT3 AFG1L	1.59e-03	1261	77	10	EFO_0004338
Disease	chronic hepatitis B virus infection	CD40 NOTCH4	1.79e-03	24	77	2	EFO_0004239
Disease	serum alanine aminotransferase measurement	EPHA2 LAMA5 PNPLA3 TNFRSF10B RGS12 NOTCH4 OR2H2 AFG1L	1.92e-03	869	77	8	EFO_0004735
Disease	peak expiratory flow	EYS MYPN ERCC6L2 RREB1 LTBP4 FBN3	1.93e-03	498	77	6	EFO_0009718
Disease	Adenocarcinoma of large intestine	ERBB4 CAMKK2 PRKG2	2.05e-03	96	77	3	C1319315
Disease	Depressive Symptoms	FASN AVP	2.10e-03	26	77	2	C0086132
Disease	coronary artery disease (is_implicated_in)	KL KALRN PNPLA3	2.30e-03	100	77	3	DOID:3393 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
GEFREFENGSICVEC	ERBB4	541	Q15303
DCFEPVSPEFCGKEA	ABCA9	466	Q8IUA7
FIETGEECDCGTPAE	ADAM22	451	Q9P0K1
GTVADCTFEELCERP	AFG1L	341	Q8WV93
CDDSVGYFVEPCIVE	ALDH4A1	421	P30038
FCEVPVEAVDAGDCD	DMAC2	121	Q9NW81
CEIVVDCGPFTDRSG	DICER1	251	Q9UPY3
TCDDVNECESFPGVC	FBN3	866	Q75N90
EGEVCCPVFACIQEF	ARRDC4	376	Q8NCT1
PCASDAGCIFIEENF	RAI1	1881	Q7Z5J4
LPPTFFCGVCSDTDE	RANBP2	2731	P49792
EECFCGSSVTVPEIE	RAPH1	386	Q70E73
GDFTFECNCLPETVR	NOTCH2NLA	201	Q7Z3S9
PGECTFEQDECTFTQ	MAMDC2	506	Q7Z304
SCEPEFKADCASGIF	AP1G1	391	O43747
VGCCSFIADDLDDSF	DSG3	831	P32926
VCYFSEVSCDGDVPD	IL17RA	501	Q96F46
FCPDRQVDDFVCEVP	OR2H2	166	O95918
TEDSFVCQCSEGFLI	MATN2	461	O00339
ECDEQFSGPFCEVSA	EYS	281	Q5T1H1
CNECLDGVPFTVDSE	LIMD1	566	Q9UGP4
VGEDCPVFDGLFEFC	HDAC1	96	Q13547
LSFCDVTEIPCGDVY	FNDC7	676	Q5VTL7
GEDVEETFCLNFTIC	HERC3	846	Q15034
TISFGDVDCDFCPVE	JPH1	256	Q9HDC5
CSSDDPELCAVTFVD	GLB1	626	P16278
YDEDVVCDVCRSPEG	JADE2	196	Q9NQC1
FDGVCGAPEDIECRS	MUC2	1326	Q02817
DEVVDALVCSCFIPF	PNPLA3	136	Q9NST1
EECTCVYEFQEGAPV	DCAF10	436	Q5QP82
CETFPEDEALGVSCS	FAM169B	101	Q8N8A8
EETCINVCRVDFSFP	KALRN	2886	O60229
VCDGIFDCPNGTDES	LRP2	1331	P98164
ETDCFDASDEPASCG	LRP2	2886	P98164
ACPFVEVEICGAEYD	PLCG2	1081	P16885
ERCDVCAEGFTGFPS	LAMA5	456	O15230
DPFCCEVICDDGTSV	INSL4	121	Q14641
VGSDDEEIPFKCFIC	RNF113A	251	O15541
EIAEDPGTCEICAYA	GUCA2A	96	Q02747
GDFTFECNCLPETVR	NOTCH2NLC	201	P0DPK4
GSFDEPTSKFCVACV	PRKG2	546	Q13237
GCTFEEASDPAVPCE	PTPRU	26	Q92729
EVVECGFYPDELCSA	GCNT7	41	Q6ZNI0
LGECEVSCSAFVEFV	FBXL3	366	Q9UKT7
PEGATSCECEEGFFR	EPHA2	301	P29317
QVGFVDVEFCTTCGE	ANKMY2	311	Q8IV38
CADVNECLEGDFCFP	LTBP4	876	Q8N2S1
SFIVVTECEPGCAVD	CAMKK2	51	Q96RR4
CVDEGLEPTCFERTE	FMO2	21	Q99518
QIGEVFECTFTCGAD	KCNMB4	61	Q86W47
PETLERFCPEEFTVC	KL	956	Q9UEF7
RFCPEEFTVCTECSF	KL	961	Q9UEF7
EEYVAFSEPCDCSGQ	DNAH9	1661	Q9NYC9
ACDLCSDFSDEEPVG	ERCC6L2	761	Q5T890
TPGCEAEAETEAICF	FASN	2356	P49327
CEACGKDFLFTPTEV	DHX34	1121	Q14147
DCDGFSTFDVPIFTE	HMG20B	176	Q9P0W2
DAGFPVVCCEDVFLS	SAP25	71	Q8TEE9
GEEKFTFIEECVNPC	CCT6B	356	Q92526
ECEPAFYTCVEVTAG	SMC3	541	Q9UQE7
CPESCEAQDTVFTLD	SSPOP	4666	A2VEC9
PGFSGTRCEEDIDEC	NOTCH4	541	Q99466
EEFCPECSVEFTLDV	POLR2C	91	P19387
CVDEVDSGEPCSFDV	BCL2L15	36	Q5TBC7
FVCGCQVVSVFTEEE	NKAIN4	161	Q8IVV8
FDIIEGLCCVDATTF	TPRA1	251	Q86W33
ENSFKCEVCEESFPT	ZXDB	361	P98169
ECKECGNAFSFPSEI	ZNF20	256	P17024
FECTADPDTNGCLEF	RGS12	361	O14924
AAELVDAFCAPDTVC	RREB1	741	Q92766
IPNDGTFCTDIDECE	SUSD1	116	Q6UWL2
QKCSQCEEGFDFPED	ZNF521	246	Q96K83
IFCGESFGTEVELQC	ZNF521	786	Q96K83
FGVCCNDESCVTEPE	AVP	101	P01185
NDESCVTEPECREGF	AVP	106	P01185
VCQCEEGTFREEDSP	TNFRSF10B	136	O14763
VSPEFVDEALCACEE	TTLL3	191	Q9Y4R7
FPGCQCEVETFGLFD	TSKU	21	Q8WUA8
ECFHDCSASFEEEPG	TTC1	61	Q99614
FVEFADCCLGIVEPS	ZNHIT3	136	Q15649
CTEFTETECLPCGES	CD40	51	P25942
ETECLPCGESEFLDT	CD40	56	P25942
AADEGFDCVSCQPYV	KMT2D	1546	O14686
VEEFVVAEECSPCSN	JTB	51	O76095
VIAEVFAEDSGCFTC	MYPN	501	Q86TC9