Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionneuroligin family protein binding

NRXN1 NRXN2

2.97e-055352GO:0097109
GeneOntologyMolecularFunctionprotein domain specific binding

SLC34A2 DMD MUC17 SLC34A1 CNOT1 SHANK3 SON GABRR3

1.08e-04875358GO:0019904
GeneOntologyMolecularFunctionphosphorylation-dependent protein binding

ANK2 ANK3

1.33e-0410352GO:0140031
GeneOntologyMolecularFunctionsodium:phosphate symporter activity

SLC34A2 SLC34A1

1.95e-0412352GO:0005436
GeneOntologyMolecularFunctionsolute:sodium symporter activity

SLC5A11 SLC34A2 SLC34A1

3.83e-0481353GO:0015370
GeneOntologyMolecularFunctionstructural molecule activity

DMD BSN ANK2 ANK3 MUC17 SHANK3 NUP153

7.73e-04891357GO:0005198
GeneOntologyMolecularFunctionphosphate transmembrane transporter activity

SLC34A2 SLC34A1

8.04e-0424352GO:0005315
GeneOntologyMolecularFunctioncytoskeletal anchor activity

ANK2 ANK3

8.04e-0424352GO:0008093
GeneOntologyMolecularFunctionsolute:monoatomic cation symporter activity

SLC5A11 SLC34A2 SLC34A1

1.18e-03119353GO:0015294
GeneOntologyMolecularFunctionPDZ domain binding

DMD MUC17 SLC34A1

1.29e-03123353GO:0030165
GeneOntologyMolecularFunctionstructural constituent of cytoskeleton

DMD ANK2 ANK3

1.52e-03130353GO:0005200
GeneOntologyMolecularFunctionspectrin binding

ANK2 ANK3

1.62e-0334352GO:0030507
GeneOntologyMolecularFunctionsymporter activity

SLC5A11 SLC34A2 SLC34A1

2.28e-03150353GO:0015293
GeneOntologyMolecularFunctionstructural constituent of synapse

BSN SHANK3

2.46e-0342352GO:0098918
GeneOntologyMolecularFunctionion channel regulator activity

ANK2 NRXN1 NRXN2

2.84e-03162353GO:0099106
GeneOntologyMolecularFunctioninorganic anion transmembrane transporter activity

SLC34A2 SLC34A1 GABRR3

3.30e-03171353GO:0015103
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC5A11 SLC34A2 SLC34A1

3.30e-03171353GO:0015081
GeneOntologyMolecularFunctiontransmembrane transporter binding

CBARP ANK2 ANK3

3.36e-03172353GO:0044325
GeneOntologyMolecularFunctionchannel regulator activity

ANK2 NRXN1 NRXN2

3.47e-03174353GO:0016247
GeneOntologyMolecularFunctiontransporter regulator activity

ANK2 NRXN1 NRXN2

3.64e-03177353GO:0141108
GeneOntologyMolecularFunctioncalcium channel regulator activity

NRXN1 NRXN2

4.03e-0354352GO:0005246
GeneOntologyMolecularFunctionzinc ion binding

TET2 ZMYM1 DMD SMPDL3A SHANK3 NUP153

4.15e-03891356GO:0008270
GeneOntologyMolecularFunctionmodification-dependent protein binding

BPTF ANK2 ANK3

5.55e-03206353GO:0140030
GeneOntologyBiologicalProcessvocal learning

NRXN1 NRXN2 SHANK3

1.56e-077353GO:0042297
GeneOntologyBiologicalProcessimitative learning

NRXN1 NRXN2 SHANK3

1.56e-077353GO:0098596
GeneOntologyBiologicalProcessobservational learning

NRXN1 NRXN2 SHANK3

3.73e-079353GO:0098597
GeneOntologyBiologicalProcessregulation of transporter activity

SLC5A11 CBARP DMD ANK2 ANK3 NRXN1 SHANK3

5.95e-07299357GO:0032409
GeneOntologyBiologicalProcesslearned vocalization behavior or vocal learning

NRXN1 NRXN2 SHANK3

7.32e-0711353GO:0098598
GeneOntologyBiologicalProcessauditory behavior

NRXN1 NRXN2 SHANK3

1.61e-0614353GO:0031223
GeneOntologyBiologicalProcessguanylate kinase-associated protein clustering

NRXN1 SHANK3

2.80e-062352GO:0097117
GeneOntologyBiologicalProcessmechanosensory behavior

NRXN1 NRXN2 SHANK3

2.99e-0617353GO:0007638
GeneOntologyBiologicalProcessregulation of membrane potential

DMD ANK2 ANK3 NRXN1 SLC34A1 SHANK3 SEZ6 GABRR3

3.42e-06559358GO:0042391
GeneOntologyBiologicalProcessregulation of monoatomic ion transmembrane transporter activity

CBARP DMD ANK2 ANK3 NRXN1 SHANK3

4.14e-06256356GO:0032412
GeneOntologyBiologicalProcessregulation of transmembrane transporter activity

CBARP DMD ANK2 ANK3 NRXN1 SHANK3

5.16e-06266356GO:0022898
GeneOntologyBiologicalProcessvocalization behavior

NRXN1 NRXN2 SHANK3

8.84e-0624353GO:0071625
GeneOntologyBiologicalProcessneuroligin clustering involved in postsynaptic membrane assembly

NRXN1 NRXN2

1.67e-054352GO:0097118
GeneOntologyBiologicalProcesspositive regulation of ion transmembrane transporter activity

DMD ANK2 ANK3 SHANK3

2.15e-0597354GO:0032414
GeneOntologyBiologicalProcesspostsynaptic density assembly

NRXN1 NRXN2 SHANK3

2.58e-0534353GO:0097107
GeneOntologyBiologicalProcesspresynaptic active zone assembly

BSN NRXN1

2.79e-055352GO:1904071
GeneOntologyBiologicalProcessgephyrin clustering involved in postsynaptic density assembly

NRXN1 NRXN2

2.79e-055352GO:0097116
GeneOntologyBiologicalProcesspositive regulation of transporter activity

DMD ANK2 ANK3 SHANK3

3.17e-05107354GO:0032411
GeneOntologyBiologicalProcessresponse to auditory stimulus

NRXN1 NRXN2 SHANK3

3.34e-0537353GO:0010996
GeneOntologyBiologicalProcessregulation of grooming behavior

NRXN1 SHANK3

4.18e-056352GO:2000821
GeneOntologyBiologicalProcessNMDA glutamate receptor clustering

NRXN1 SHANK3

4.18e-056352GO:0097114
GeneOntologyBiologicalProcessregulation of transmembrane transport

CBARP DMD ANK2 ANK3 NRXN1 SLC34A1 SHANK3

5.01e-05589357GO:0034762
GeneOntologyBiologicalProcesspostsynaptic specialization assembly

NRXN1 NRXN2 SHANK3

5.65e-0544353GO:0098698
GeneOntologyBiologicalProcessexcitatory synapse assembly

NRXN1 NRXN2 SHANK3

6.46e-0546353GO:1904861
GeneOntologyBiologicalProcessmonoatomic ion transport

SLC5A11 SLC34A2 HAVCR1 CBARP DMD ANK2 ANK3 SLC34A1 SHANK3 GABRR3

6.56e-0513743510GO:0006811
GeneOntologyBiologicalProcessregulation of cation channel activity

CBARP DMD ANK2 ANK3

8.55e-05138354GO:2001257
GeneOntologyBiologicalProcesspositive regulation of transmembrane transport

DMD ANK2 ANK3 SLC34A1 SHANK3

9.18e-05273355GO:0034764
GeneOntologyBiologicalProcesssodium ion transport

SLC5A11 SLC34A2 DMD ANK3 SLC34A1

9.51e-05275355GO:0006814
GeneOntologyBiologicalProcessregulation of neurotransmitter receptor activity

NRXN1 NRXN2 SHANK3

1.17e-0456353GO:0099601
GeneOntologyBiologicalProcesspostsynaptic membrane organization

NRXN1 NRXN2 SHANK3

1.17e-0456353GO:0001941
GeneOntologyBiologicalProcesspresynaptic active zone organization

BSN NRXN1

1.25e-0410352GO:1990709
GeneOntologyBiologicalProcesspostsynaptic density organization

NRXN1 NRXN2 SHANK3

1.30e-0458353GO:0097106
GeneOntologyBiologicalProcesspostsynaptic density protein 95 clustering

NRXN1 NRXN2

1.52e-0411352GO:0097119
GeneOntologyBiologicalProcesspostsynaptic membrane assembly

NRXN1 NRXN2

1.52e-0411352GO:0097104
GeneOntologyBiologicalProcessintracellular phosphate ion homeostasis

SLC34A2 SLC34A1

1.52e-0411352GO:0030643
GeneOntologyBiologicalProcessmembrane assembly

ANK3 NRXN1 NRXN2

1.74e-0464353GO:0071709
GeneOntologyBiologicalProcesscell junction organization

MYADM BSN ANK2 ANK3 NRXN1 NRXN2 SHANK3 SEZ6

1.81e-04974358GO:0034330
GeneOntologyBiologicalProcesscell junction maintenance

MYADM BSN NRXN1

1.82e-0465353GO:0034331
GeneOntologyBiologicalProcesssodium-dependent phosphate transport

SLC34A2 SLC34A1

2.16e-0413352GO:0044341
GeneOntologyBiologicalProcessmetal ion transport

SLC5A11 SLC34A2 HAVCR1 CBARP DMD ANK2 ANK3 SLC34A1

2.17e-041000358GO:0030001
GeneOntologyBiologicalProcesspostsynaptic specialization organization

NRXN1 NRXN2 SHANK3

2.36e-0471353GO:0099084
GeneOntologyBiologicalProcessmembrane biogenesis

ANK3 NRXN1 NRXN2

2.57e-0473353GO:0044091
GeneOntologyBiologicalProcesssocial behavior

NRXN1 NRXN2 SHANK3

2.67e-0474353GO:0035176
GeneOntologyBiologicalProcessbiological process involved in intraspecies interaction between organisms

NRXN1 NRXN2 SHANK3

2.89e-0476353GO:0051703
GeneOntologyBiologicalProcesspositive regulation of monoatomic ion transmembrane transport

DMD ANK2 ANK3 SHANK3

3.04e-04192354GO:0034767
GeneOntologyBiologicalProcesslocalization within membrane

ARFGEF2 MYADM ANK2 ANK3 NRXN1 NRXN2 SHANK3

3.29e-04798357GO:0051668
GeneOntologyBiologicalProcesspositive regulation of sodium ion transmembrane transporter activity

DMD ANK3

3.31e-0416352GO:2000651
GeneOntologyBiologicalProcessneuron cell-cell adhesion

NRXN1 NRXN2

3.31e-0416352GO:0007158
GeneOntologyBiologicalProcessreceptor clustering

NRXN1 NRXN2 SHANK3

3.75e-0483353GO:0043113
GeneOntologyBiologicalProcessadult behavior

NRXN1 NRXN2 SHANK3 SEZ6

3.76e-04203354GO:0030534
GeneOntologyBiologicalProcesssodium ion transmembrane transport

SLC34A2 DMD ANK3 SLC34A1

4.12e-04208354GO:0035725
GeneOntologyBiologicalProcesscardiac muscle cell action potential

DMD ANK2 ANK3

4.30e-0487353GO:0086001
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

SLC34A2 CBARP DMD ANK2 ANK3 SLC34A1 SHANK3 GABRR3

4.53e-041115358GO:0034220
GeneOntologyBiologicalProcessregulation of synaptic vesicle cycle

BSN NRXN1

4.70e-0419352GO:0098693
GeneOntologyBiologicalProcessregulation of calcium ion transmembrane transporter activity

CBARP DMD ANK2

5.07e-0492353GO:1901019
GeneOntologyBiologicalProcessregulation of protein kinase C signaling

MYADM SEZ6

5.21e-0420352GO:0090036
GeneOntologyBiologicalProcesspostsynapse assembly

NRXN1 NRXN2 SHANK3

5.23e-0493353GO:0099068
GeneOntologyBiologicalProcessmonoatomic cation transport

SLC5A11 SLC34A2 HAVCR1 CBARP DMD ANK2 ANK3 SLC34A1

5.79e-041157358GO:0006812
GeneOntologyBiologicalProcessneurotransmitter-gated ion channel clustering

NRXN1 SHANK3

6.33e-0422352GO:0072578
GeneOntologyBiologicalProcesspositive regulation of sodium ion transmembrane transport

DMD ANK3

6.33e-0422352GO:1902307
GeneOntologyBiologicalProcessregulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion

DMD ANK2

6.33e-0422352GO:0010881
GeneOntologyBiologicalProcesssynaptic vesicle clustering

BSN NRXN1

6.33e-0422352GO:0097091
GeneOntologyBiologicalProcessregulation of monoatomic ion transmembrane transport

CBARP DMD ANK2 ANK3 SHANK3

6.49e-04417355GO:0034765
GeneOntologyBiologicalProcesscellular component maintenance

MYADM BSN NRXN1

6.66e-04101353GO:0043954
GeneOntologyBiologicalProcessmembrane depolarization during cardiac muscle cell action potential

ANK2 ANK3

6.92e-0423352GO:0086012
GeneOntologyBiologicalProcessphosphate ion homeostasis

SLC34A2 SLC34A1

6.92e-0423352GO:0055062
GeneOntologyBiologicalProcessmembrane organization

HAVCR1 MYADM ANK2 ANK3 NRXN1 NRXN2 SHANK3

7.42e-04914357GO:0061024
GeneOntologyBiologicalProcessgrooming behavior

NRXN1 SHANK3

7.54e-0424352GO:0007625
GeneOntologyBiologicalProcessresponse to mechanical stimulus

DMD NRXN1 NRXN2 SHANK3

7.85e-04247354GO:0009612
GeneOntologyBiologicalProcesspositive regulation of membrane potential

ANK3 SLC34A1

8.19e-0425352GO:0045838
GeneOntologyBiologicalProcessresponse to magnesium ion

ANK3 SLC34A1

8.19e-0425352GO:0032026
GeneOntologyBiologicalProcessregulation of AMPA receptor activity

NRXN1 SHANK3

8.19e-0425352GO:2000311
GeneOntologyBiologicalProcessanterograde trans-synaptic signaling

DMD BSN NRXN1 NRXN2 SHANK3 SEZ6 GABRR3

8.28e-04931357GO:0098916
GeneOntologyBiologicalProcesschemical synaptic transmission

DMD BSN NRXN1 NRXN2 SHANK3 SEZ6 GABRR3

8.28e-04931357GO:0007268
GeneOntologyBiologicalProcesstrans-synaptic signaling

DMD BSN NRXN1 NRXN2 SHANK3 SEZ6 GABRR3

8.71e-04939357GO:0099537
GeneOntologyBiologicalProcesssynapse organization

BSN ANK3 NRXN1 NRXN2 SHANK3 SEZ6

9.36e-04685356GO:0050808
GeneOntologyBiologicalProcessprotein localization to synapse

BSN NRXN1 NRXN2

9.70e-04115353GO:0035418
GeneOntologyBiologicalProcessregulation of cardiac muscle contraction by calcium ion signaling

DMD ANK2

1.03e-0328352GO:0010882
GeneOntologyBiologicalProcesspositive regulation of monoatomic ion transport

DMD ANK2 ANK3 SHANK3

1.03e-03266354GO:0043270
GeneOntologyBiologicalProcessprotein localization to membrane

MYADM ANK2 ANK3 NRXN1 NRXN2 SHANK3

1.09e-03705356GO:0072657
GeneOntologyBiologicalProcesssynaptic signaling

DMD BSN NRXN1 NRXN2 SHANK3 SEZ6 GABRR3

1.09e-03976357GO:0099536
GeneOntologyBiologicalProcessphosphate ion transport

SLC34A2 SLC34A1

1.26e-0331352GO:0006817
GeneOntologyBiologicalProcessregulation of system process

DMD ANK2 NRXN1 NRXN2 SHANK3 PPP1R12B

1.34e-03734356GO:0044057
GeneOntologyBiologicalProcessexcitatory postsynaptic potential

NRXN1 SHANK3 SEZ6

1.38e-03130353GO:0060079
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

SLC34A2 CBARP DMD ANK2 ANK3 SLC34A1 GABRR3

1.39e-031017357GO:0098660
GeneOntologyBiologicalProcessregulation of signaling receptor activity

NRXN1 NRXN2 SHANK3

1.41e-03131353GO:0010469
GeneOntologyBiologicalProcessregulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum

DMD ANK2

1.43e-0333352GO:0010880
GeneOntologyBiologicalProcessmembrane depolarization during action potential

ANK2 ANK3

1.70e-0336352GO:0086010
GeneOntologyBiologicalProcesssynapse assembly

BSN NRXN1 NRXN2 SHANK3

1.77e-03308354GO:0007416
GeneOntologyBiologicalProcessrelease of sequestered calcium ion into cytosol by sarcoplasmic reticulum

DMD ANK2

1.79e-0337352GO:0014808
GeneOntologyCellularComponentsynaptic membrane

DMD BSN ANK2 ANK3 NRXN1 NRXN2 SHANK3 GABRR3

5.30e-06583368GO:0097060
GeneOntologyCellularComponentcostamere

DMD ANK2 ANK3

7.06e-0622363GO:0043034
GeneOntologyCellularComponentGABA-ergic synapse

ARFGEF2 DMD BSN NRXN1 GABRR3

8.66e-06164365GO:0098982
GeneOntologyCellularComponentneuron to neuron synapse

ARFGEF2 DMD BSN ANK2 ANK3 NRXN1 SHANK3

2.62e-05523367GO:0098984
GeneOntologyCellularComponentZ disc

DMD ANK2 ANK3 PPP1R12B

1.29e-04151364GO:0030018
GeneOntologyCellularComponentbrush border

SLC34A2 HAVCR1 MUC17 SLC34A1

1.32e-04152364GO:0005903
GeneOntologyCellularComponentasymmetric synapse

ARFGEF2 DMD BSN ANK2 ANK3 SHANK3

1.49e-04477366GO:0032279
GeneOntologyCellularComponentapical plasma membrane

SLC5A11 SLC34A2 HAVCR1 ANK2 MUC17 SLC34A1

1.67e-04487366GO:0016324
GeneOntologyCellularComponentI band

DMD ANK2 ANK3 PPP1R12B

1.85e-04166364GO:0031674
GeneOntologyCellularComponentpostsynapse

ARFGEF2 DMD BSN ANK2 ANK3 SHANK3 SEZ6 GABRR3

2.75e-041018368GO:0098794
GeneOntologyCellularComponentbrush border membrane

SLC34A2 MUC17 SLC34A1

3.92e-0483363GO:0031526
GeneOntologyCellularComponentapical part of cell

SLC5A11 SLC34A2 HAVCR1 ANK2 MUC17 SLC34A1

4.75e-04592366GO:0045177
GeneOntologyCellularComponentcell surface

MUC16 HAVCR1 DMD BSN ANK3 NRXN1 MUC17 SLC34A1

4.95e-041111368GO:0009986
GeneOntologyCellularComponentcluster of actin-based cell projections

SLC34A2 HAVCR1 MUC17 SLC34A1

5.68e-04223364GO:0098862
GeneOntologyCellularComponentpostsynaptic membrane

DMD ANK2 ANK3 SHANK3 GABRR3

6.12e-04405365GO:0045211
GeneOntologyCellularComponentcell projection membrane

SLC34A2 DMD MUC17 SLC34A1 SHANK3

8.10e-04431365GO:0031253
GeneOntologyCellularComponentexcitatory synapse

BSN NRXN1 SHANK3

8.23e-04107363GO:0060076
GeneOntologyCellularComponentsarcomere

DMD ANK2 ANK3 PPP1R12B

8.58e-04249364GO:0030017
GeneOntologyCellularComponentGolgi lumen

MUC16 MUC5B MUC17

8.69e-04109363GO:0005796
GeneOntologyCellularComponentsomatodendritic compartment

ARFGEF2 BPTF DMD BSN ANK3 NRXN1 SHANK3 SEZ6

9.58e-041228368GO:0036477
GeneOntologyCellularComponentpostsynaptic density

DMD BSN ANK2 ANK3 SHANK3

9.93e-04451365GO:0014069
GeneOntologyCellularComponentmyofibril

DMD ANK2 ANK3 PPP1R12B

1.21e-03273364GO:0030016
GeneOntologyCellularComponentinhibitory synapse

BSN NRXN1

1.30e-0331362GO:0060077
GeneOntologyCellularComponentcontractile muscle fiber

DMD ANK2 ANK3 PPP1R12B

1.51e-03290364GO:0043292
GeneOntologyCellularComponentpostsynaptic specialization

DMD BSN ANK2 ANK3 SHANK3

1.61e-03503365GO:0099572
GeneOntologyCellularComponentpresynaptic active zone

BSN NRXN1 NRXN2

1.82e-03141363GO:0048786
GeneOntologyCellularComponentdendrite

ARFGEF2 BPTF BSN ANK3 SHANK3 SEZ6

3.19e-03858366GO:0030425
GeneOntologyCellularComponentdendritic tree

ARFGEF2 BPTF BSN ANK3 SHANK3 SEZ6

3.23e-03860366GO:0097447
GeneOntologyCellularComponentexocytic vesicle membrane

CBARP DMD BSN

3.58e-03179363GO:0099501
GeneOntologyCellularComponentsynaptic vesicle membrane

CBARP DMD BSN

3.58e-03179363GO:0030672
GeneOntologyCellularComponentA band

ANK2 PPP1R12B

3.62e-0352362GO:0031672
GeneOntologyCellularComponentpresynapse

ARFGEF2 CBARP DMD BSN NRXN1 NRXN2

3.74e-03886366GO:0098793
GeneOntologyCellularComponentsarcolemma

DMD ANK2 ANK3

4.23e-03190363GO:0042383
GeneOntologyCellularComponentperinuclear region of cytoplasm

ARFGEF2 BPTF DMD ANK2 SLC34A1 SEZ6

4.83e-03934366GO:0048471
GeneOntologyCellularComponentintercalated disc

ANK2 ANK3

6.12e-0368362GO:0014704
GeneOntologyCellularComponentpresynaptic active zone membrane

NRXN1 NRXN2

7.98e-0378362GO:0048787
GeneOntologyCellularComponentT-tubule

ANK2 ANK3

8.17e-0379362GO:0030315
GeneOntologyCellularComponentdendritic spine

ARFGEF2 SHANK3 SEZ6

8.26e-03242363GO:0043197
GeneOntologyCellularComponentneuron spine

ARFGEF2 SHANK3 SEZ6

8.73e-03247363GO:0044309
GeneOntologyCellularComponentlateral plasma membrane

DMD ANK3

1.05e-0290362GO:0016328
MousePhenoabnormal CNS synaptic transmission

BPTF CBARP MUC5B AFF2 BSN ANK2 NRXN1 NRXN2 SHANK3 SEZ6

8.04e-069852710MP:0002206
MousePhenoabnormal synaptic transmission

BPTF CBARP MUC5B AFF2 BSN ANK2 NRXN1 NRXN2 SHANK3 SEZ6

1.67e-0510702710MP:0003635
MousePhenoabnormal synaptic physiology

BPTF CBARP MUC5B AFF2 BSN ANK2 NRXN1 NRXN2 SHANK3 SEZ6

1.76e-0510762710MP:0021009
MousePhenodecreased stereotypic behavior

CBARP SHANK3

9.99e-058272MP:0003908
DomainNa_Pi_cotrans

SLC34A2 SLC34A1

1.02e-053352PF02690
DomainNa/Pi_transpt

SLC34A2 SLC34A1

1.02e-053352IPR003841
DomainSyndecan

NRXN1 NRXN2

7.12e-057352PF01034
DomainSyndecan/Neurexin_dom

NRXN1 NRXN2

7.12e-057352IPR027789
DomainANK_REPEAT

MUC16 ANK2 ANK3 SHANK3 PPP1R12B

1.02e-04253355PS50088
DomainANK_REP_REGION

MUC16 ANK2 ANK3 SHANK3 PPP1R12B

1.04e-04254355PS50297
DomainZU5

ANK2 ANK3

1.22e-049352SM00218
DomainZU5

ANK2 ANK3

1.52e-0410352PS51145
DomainZU5_dom

ANK2 ANK3

2.23e-0412352IPR000906
DomainTIL

MUC5B ZAN

2.23e-0412352PF01826
DomainC8

MUC5B ZAN

2.23e-0412352PF08742
DomainZU5

ANK2 ANK3

2.23e-0412352PF00791
DomainUnchr_dom_Cys-rich

MUC5B ZAN

2.63e-0413352IPR014853
DomainC8

MUC5B ZAN

2.63e-0413352SM00832
DomainSEA

MUC16 MUC17

3.06e-0414352SM00200
DomainNeurexin-like

NRXN1 NRXN2

3.06e-0414352IPR003585
Domain4.1m

NRXN1 NRXN2

3.06e-0414352SM00294
DomainTIL_dom

MUC5B ZAN

3.06e-0414352IPR002919
Domain-

MUC16 MUC17

3.53e-04153523.30.70.960
DomainVWFD

MUC5B ZAN

4.03e-0416352PS51233
DomainVWD

MUC5B ZAN

4.03e-0416352SM00216
DomainVWF_type-D

MUC5B ZAN

4.03e-0416352IPR001846
DomainVWD

MUC5B ZAN

4.03e-0416352PF00094
DomainVWC_out

MUC5B ZAN

5.72e-0419352SM00215
DomainAnk_2

ANK2 ANK3 SHANK3 PPP1R12B

6.76e-04215354PF12796
DomainSEA

MUC16 MUC17

7.70e-0422352PF01390
DomainSEA

MUC16 MUC17

8.42e-0423352PS50024
DomainSEA_dom

MUC16 MUC17

8.42e-0423352IPR000082
DomainEGF_3

ZAN NRXN1 NRXN2 MUC17

9.42e-04235354PS50026
DomainEGF

ZAN NRXN1 NRXN2 MUC17

9.42e-04235354SM00181
Domain-

ANK2 ANK3 SHANK3 PPP1R12B

1.15e-032483541.25.40.20
DomainDEATH

ANK2 ANK3

1.16e-0327352SM00005
DomainEGF-like_dom

ZAN NRXN1 NRXN2 MUC17

1.17e-03249354IPR000742
DomainANK

ANK2 ANK3 SHANK3 PPP1R12B

1.20e-03251354SM00248
DomainAnkyrin_rpt-contain_dom

ANK2 ANK3 SHANK3 PPP1R12B

1.26e-03254354IPR020683
DomainEGF_1

ZAN NRXN1 NRXN2 MUC17

1.27e-03255354PS00022
DomainEGF-like_CS

ZAN NRXN1 NRXN2 MUC17

1.39e-03261354IPR013032
DomainAnkyrin_rpt

ANK2 ANK3 SHANK3 PPP1R12B

1.41e-03262354IPR002110
DomainEGF_2

ZAN NRXN1 NRXN2 MUC17

1.47e-03265354PS01186
DomainEGF

ZAN NRXN1 NRXN2

1.68e-03126353PF00008
DomainDeath

ANK2 ANK3

1.74e-0333352PF00531
DomainVWFC_1

MUC5B ZAN

2.07e-0336352PS01208
DomainDeath_domain

ANK2 ANK3

2.30e-0338352IPR000488
DomainDEATH_DOMAIN

ANK2 ANK3

2.30e-0338352PS50017
DomainLAM_G_DOMAIN

NRXN1 NRXN2

2.30e-0338352PS50025
DomainVWC

MUC5B ZAN

2.30e-0338352SM00214
DomainVWFC_2

MUC5B ZAN

2.30e-0338352PS50184
DomainLaminin_G_2

NRXN1 NRXN2

2.54e-0340352PF02210
DomainVWF_dom

MUC5B ZAN

2.80e-0342352IPR001007
DomainLamG

NRXN1 NRXN2

3.07e-0344352SM00282
DomainLaminin_G

NRXN1 NRXN2

5.28e-0358352IPR001791
PathwayREACTOME_DEFECTIVE_GALNT3_CAUSES_HFTC

MUC16 MUC5B MUC17

3.86e-0616283M27410
PathwayREACTOME_DEFECTIVE_C1GALT1C1_CAUSES_TNPS

MUC16 MUC5B MUC17

4.68e-0617283M27412
PathwayREACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS

MUC16 MUC5B MUC17

9.11e-0621283MM15706
PathwayREACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS

MUC16 MUC5B MUC17

1.21e-0523283M556
PathwayREACTOME_DECTIN_2_FAMILY

MUC16 MUC5B MUC17

1.77e-0526283M27483
PathwayREACTOME_NEUREXINS_AND_NEUROLIGINS

NRXN1 NRXN2 SHANK3

3.35e-0532283MM15326
PathwayREACTOME_SODIUM_COUPLED_PHOSPHATE_COTRANSPORTERS

SLC34A2 SLC34A1

3.79e-055282M27345
PathwayREACTOME_SODIUM_COUPLED_PHOSPHATE_COTRANSPORTERS

SLC34A2 SLC34A1

3.79e-055282MM15085
PathwayREACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS

MUC16 MUC5B MUC17

2.23e-0460283MM15636
PathwayREACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS

MUC16 MUC5B MUC17

2.45e-0462283M546
PathwayREACTOME_PROTEIN_PROTEIN_INTERACTIONS_AT_SYNAPSES

NRXN1 NRXN2 SHANK3

3.09e-0467283MM15327
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

MUC16 MUC5B MUC17

3.23e-0468283M27303
PathwayREACTOME_SURFACTANT_METABOLISM

SLC34A2 SLC34A1

9.38e-0423282MM15279
PathwayREACTOME_SLC_TRANSPORTER_DISORDERS

SLC34A2 SLC34A1 NUP153

9.69e-0499283M27474
PathwayREACTOME_O_LINKED_GLYCOSYLATION

MUC16 MUC5B MUC17

1.28e-03109283MM15164
PathwayWP_HIPPOCAMPAL_SYNAPTOGENESIS_AND_NEUROGENESIS

NRXN1 NRXN2

1.29e-0327282M45550
PathwayREACTOME_O_LINKED_GLYCOSYLATION

MUC16 MUC5B MUC17

1.35e-03111283M27416
PathwayREACTOME_DISEASES_OF_METABOLISM

MUC16 SLC34A2 MUC5B MUC17

1.41e-03250284M27554
PathwayREACTOME_SURFACTANT_METABOLISM

SLC34A2 SLC34A1

1.60e-0330282M27566
PathwayREACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS

ANK2 ANK3

1.71e-0331282M877
PathwayWP_DISRUPTION_OF_POSTSYNAPTIC_SIGNALING_BY_CNV

NRXN1 NRXN2

1.93e-0333282M39875
PathwayREACTOME_C_TYPE_LECTIN_RECEPTORS_CLRS

MUC16 MUC5B MUC17

2.62e-03140283M27484
PathwayREACTOME_DISEASES_OF_GLYCOSYLATION

MUC16 MUC5B MUC17

2.78e-03143283M27275
PathwayREACTOME_NEURONAL_SYSTEM

NRXN1 NRXN2 SHANK3 GABRR3

4.09e-03335284MM14503
Pubmed

An ankyrin-based mechanism for functional organization of dystrophin and dystroglycan.

DMD ANK2 ANK3

1.02e-08536319109891
Pubmed

Differential interactions of cerebellin precursor protein (Cbln) subtypes and neurexin variants for synapse formation of cortical neurons.

BSN NRXN1 NRXN2

8.52e-08936321356198
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

ZMYM1 AFF2 BSN ANK3 CTDSPL2 NUP153 SON

2.58e-0743036735044719
Pubmed

Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux.

MUC16 MUC5B MUC17

8.22e-071836318834073
Pubmed

The nuclear pore protein Nup153 associates with chromatin and regulates cardiac gene expression in dystrophic mdx hearts.

DMD NUP153

1.04e-06236228513807
Pubmed

Mutations in NRXN1 and NRXN2 in a patient with early-onset epileptic encephalopathy and respiratory depression.

NRXN1 NRXN2

1.04e-06236230709877
Pubmed

The ankyrin-B C-terminal domain determines activity of ankyrin-B/G chimeras in rescue of abnormal inositol 1,4,5-trisphosphate and ryanodine receptor distribution in ankyrin-B (-/-) neonatal cardiomyocytes.

ANK2 ANK3

1.04e-06236211781319
Pubmed

Structural basis of diverse membrane target recognitions by ankyrins.

ANK2 ANK3

1.04e-06236225383926
Pubmed

The role of an intracellular cysteine stretch in the sorting of the type II Na/phosphate cotransporter.

SLC34A2 SLC34A1

1.04e-06236217574207
Pubmed

Neurexins: synaptic cell surface proteins related to the alpha-latrotoxin receptor and laminin.

NRXN1 NRXN2

1.04e-0623621621094
Pubmed

Type II Na+-Pi cotransporters in osteoblast mineral formation: regulation by inorganic phosphate.

SLC34A2 SLC34A1

1.04e-06236217310099
Pubmed

Heterozygous deletion of α-neurexin I or α-neurexin II results in behaviors relevant to autism and schizophrenia.

NRXN1 NRXN2

1.04e-06236226595880
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

ARFGEF2 MYADM DMD BSN ANK2 ANK3 NRXN2 CNOT1 SHANK3 PPP1R12B

1.29e-061431361037142655
Pubmed

Cbln1 regulates axon growth and guidance in multiple neural regions.

NRXN1 NRXN2 LHX9

1.55e-062236336395107
Pubmed

Endogenous β-neurexins on axons and within synapses show regulated dynamic behavior.

NRXN1 NRXN2

3.12e-06336234133920
Pubmed

Conditional Knockout of Neurexins Alters the Contribution of Calcium Channel Subtypes to Presynaptic Ca2+ Influx.

NRXN1 NRXN2

3.12e-06336238891114
Pubmed

Expression of renal and intestinal Na/Pi cotransporters in the absence of GABARAP.

SLC34A2 SLC34A1

3.12e-06336220354864
Pubmed

Growth-related renal type II Na/Pi cotransporter.

SLC34A2 SLC34A1

3.12e-06336211880379
Pubmed

Truncating mutations in NRXN2 and NRXN1 in autism spectrum disorders and schizophrenia.

NRXN1 NRXN2

3.12e-06336221424692
Pubmed

DUSP28 links regulation of Mucin 5B and Mucin 16 to migration and survival of AsPC-1 human pancreatic cancer cells.

MUC16 MUC5B

3.12e-06336227230679
Pubmed

The within-subject application of diffusion tensor MRI and CLARITY reveals brain structural changes in Nrxn2 deletion mice.

NRXN1 NRXN2

3.12e-06336230858964
Pubmed

Neurexins 1-3 Each Have a Distinct Pattern of Expression in the Early Developing Human Cerebral Cortex.

NRXN1 NRXN2

3.12e-06336228013231
Pubmed

The ammonium transporter RhBG: requirement of a tyrosine-based signal and ankyrin-G for basolateral targeting and membrane anchorage in polarized kidney epithelial cells.

ANK2 ANK3

3.12e-06336215611082
Pubmed

alpha-Neurexins are required for efficient transmitter release and synaptic homeostasis at the mouse neuromuscular junction.

NRXN1 NRXN2

3.12e-06336216406382
Pubmed

Ketamine Restores Thalamic-Prefrontal Cortex Functional Connectivity in a Mouse Model of Neurodevelopmental Disorder-Associated 2p16.3 Deletion.

NRXN1 NRXN2

3.12e-06336231812984
Pubmed

Human ankyrins and their contribution to disease biology: An update.

ANK2 ANK3

3.12e-06336233410423
Pubmed

Structure and evolution of neurexin genes: insight into the mechanism of alternative splicing.

NRXN1 NRXN2

3.12e-06336212036300
Pubmed

β-Neurexins Control Neural Circuits by Regulating Synaptic Endocannabinoid Signaling.

NRXN1 NRXN2

3.12e-06336226213384
Pubmed

Neurexin gene family variants as risk factors for autism spectrum disorder.

NRXN1 NRXN2

3.12e-06336229045040
Pubmed

Alternative Splicing of Presynaptic Neurexins Differentially Controls Postsynaptic NMDA and AMPA Receptor Responses.

NRXN1 NRXN2

3.12e-06336231005376
Pubmed

Structural and functional characterization of the IgSF21-neurexin2α complex and its related signaling pathways in the regulation of inhibitory synapse organization.

NRXN1 NRXN2

3.12e-06336238571813
Pubmed

Deletion of β-Neurexins in Mice Alters the Distribution of Dense-Core Vesicles in Presynapses of Hippocampal and Cerebellar Neurons.

NRXN1 NRXN2

3.12e-06336235173587
Pubmed

Dopaminergic neurons establish a distinctive axonal arbor with a majority of non-synaptic terminals.

BSN NRXN1

3.12e-06336234320240
Pubmed

Upregulation of the Na⁺-coupled phosphate cotransporters NaPi-IIa and NaPi-IIb by B-RAF.

SLC34A2 SLC34A1

3.12e-06336224258620
Pubmed

Neurexins are differentially expressed in the embryonic nervous system of mice.

NRXN1 NRXN2

3.12e-0633627722633
Pubmed

Regulated Dynamic Trafficking of Neurexins Inside and Outside of Synaptic Terminals.

NRXN1 NRXN2

3.12e-06336226446217
Pubmed

Analysis of the human neurexin genes: alternative splicing and the generation of protein diversity.

NRXN1 NRXN2

3.12e-06336211944992
Pubmed

Alternative splicing of neurexins 1-3 is modulated by neuroinflammation in the prefrontal cortex of a murine model of multiple sclerosis.

NRXN1 NRXN2

3.12e-06336233058888
Pubmed

Important contribution of alpha-neurexins to Ca2+-triggered exocytosis of secretory granules.

NRXN1 NRXN2

3.12e-06336217035546
Pubmed

Neurexins: three genes and 1001 products.

NRXN1 NRXN2

3.12e-0633629448462
Pubmed

Deletion of α-neurexin II results in autism-related behaviors in mice.

NRXN1 NRXN2

3.12e-06336225423136
Pubmed

Ankyrin-dependent Na+ channel clustering prevents neuromuscular synapse fatigue.

ANK2 ANK3

3.12e-06336234289389
Pubmed

Interactome Analysis Reveals Regulator of G Protein Signaling 14 (RGS14) is a Novel Calcium/Calmodulin (Ca2+/CaM) and CaM Kinase II (CaMKII) Binding Partner.

BSN ANK2 ANK3 SHANK3 PPP1R12B

4.11e-0623336529518331
Pubmed

Tet2- and Tet3- Mediated Cytosine Hydroxymethylation in Six2 Progenitor Cells in Mice Is Critical for Nephron Progenitor Differentiation and Nephron Endowment.

TET2 HAVCR1 SLC34A1

5.44e-063336336522157
Pubmed

Postsynaptic N-methyl-D-aspartate receptor function requires alpha-neurexins.

NRXN1 NRXN2

6.24e-06436214983056
Pubmed

Deorphanizing FAM19A proteins as pan-neurexin ligands with an unusual biosynthetic binding mechanism.

NRXN1 NRXN2

6.24e-06436232706374
Pubmed

The sodium phosphate cotransporter family and nicotinamide phosphoribosyltransferase contribute to the daily oscillation of plasma inorganic phosphate concentration.

SLC34A2 SLC34A1

6.24e-06436229398136
Pubmed

GluRδ2 assembles four neurexins into trans-synaptic triad to trigger synapse formation.

BSN NRXN1

6.24e-06436222457515
Pubmed

Targeted deletion of the tybe IIb Na(+)-dependent Pi-co-transporter, NaPi-IIb, results in early embryonic lethality.

SLC34A2 SLC34A1

6.24e-06436219233126
Pubmed

CASK: a novel dlg/PSD95 homolog with an N-terminal calmodulin-dependent protein kinase domain identified by interaction with neurexins.

NRXN1 NRXN2

6.24e-0643628786425
Pubmed

Ankyrin-B interactions with spectrin and dynactin-4 are required for dystrophin-based protection of skeletal muscle from exercise injury.

DMD ANK2

6.24e-06436221186323
Pubmed

Deletion of alpha-neurexins does not cause a major impairment of axonal pathfinding or synapse formation.

NRXN1 NRXN2

6.24e-06436217347997
Pubmed

Neurexins cluster Ca2+ channels within the presynaptic active zone.

NRXN1 NRXN2

6.24e-06436232134527
Pubmed

Autism-associated miR-873 regulates ARID1B, SHANK3 and NRXN2 involved in neurodevelopment.

NRXN2 SHANK3

6.24e-06436233262327
Pubmed

Neurexins play a crucial role in cerebellar granule cell survival by organizing autocrine machinery for neurotrophins.

NRXN1 NRXN2

6.24e-06436235385735
Pubmed

Neurexins regulate presynaptic GABAB-receptors at central synapses.

NRXN1 NRXN2

6.24e-06436233888718
Pubmed

CK2-regulated schwannomin-interacting protein IQCJ-SCHIP-1 association with AnkG contributes to the maintenance of the axon initial segment.

ANK2 ANK3

1.04e-05536225950943
Pubmed

Conditional Deletion of All Neurexins Defines Diversity of Essential Synaptic Organizer Functions for Neurexins.

NRXN1 NRXN2

1.04e-05536228472659
Pubmed

Concerted roles of LRRTM1 and SynCAM 1 in organizing prefrontal cortex synapses and cognitive functions.

NRXN1 NRXN2

1.04e-05536236709330
Pubmed

Glial ankyrins facilitate paranodal axoglial junction assembly.

ANK2 ANK3

1.04e-05536225362471
Pubmed

Trans-synaptic interaction of GluRdelta2 and Neurexin through Cbln1 mediates synapse formation in the cerebellum.

NRXN1 NRXN2

1.04e-05536220537373
Pubmed

Neuroligins and neurexins link synaptic function to cognitive disease.

NRXN1 NRXN2

1.04e-05536218923512
Pubmed

Acetylcholinesterase-transgenic mice display embryonic modulations in spinal cord choline acetyltransferase and neurexin Ibeta gene expression followed by late-onset neuromotor deterioration.

NRXN1 NRXN2

1.04e-0553629223334
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

ARFGEF2 MUC16 CBARP HCFC2 AFF2 ANK3 INPP5B

1.28e-0577736735844135
Pubmed

ELF a beta-spectrin is a neuronal precursor cell marker in developing mammalian brain; structure and organization of the elf/beta-G spectrin gene.

DMD ANK2

1.56e-05636212149647
Pubmed

Expression of Muc19/Smgc gene products during murine sublingual gland development: cytodifferentiation and maturation of salivary mucous cells.

MUC16 MUC5B

1.56e-05636219110483
Pubmed

Alpha-neurexins couple Ca2+ channels to synaptic vesicle exocytosis.

NRXN1 NRXN2

1.56e-05636212827191
Pubmed

Structures, alternative splicing, and neurexin binding of multiple neuroligins.

NRXN1 NRXN2

1.56e-0563628576240
Pubmed

In vivo assembly of the axon initial segment in motor neurons.

ANK2 ANK3

1.56e-05636223728480
Pubmed

Presynaptic α2δ-2 Calcium Channel Subunits Regulate Postsynaptic GABAA Receptor Abundance and Axonal Wiring.

NRXN1 NRXN2

1.56e-05636230683685
Pubmed

Analysis of the role of membrane polarity in polycystic kidney disease of transgenic SBM mice.

ANK2 ANK3

2.18e-0573627495297
Pubmed

Novel obscurins mediate cardiomyocyte adhesion and size via the PI3K/AKT/mTOR signaling pathway.

DMD ANK3

2.91e-05836228826662
Pubmed

Neuroligin-1 Signaling Controls LTP and NMDA Receptors by Distinct Molecular Pathways.

NRXN1 NRXN2

2.91e-05836230871858
Pubmed

Combinatorial expression of neurexins and LAR-type phosphotyrosine phosphatase receptors instructs assembly of a cerebellar circuit.

NRXN1 NRXN2

2.91e-05836237591863
Pubmed

Cellular localization of the vesicular inhibitory amino acid transporter in the mouse and human retina.

DMD BSN

2.91e-05836212115694
Pubmed

Using mouse models of autism spectrum disorders to study the neurotoxicology of gene-environment interactions.

NRXN1 SHANK3

3.73e-05936223010509
Pubmed

Potent and specific Atg8-targeting autophagy inhibitory peptides from giant ankyrins.

ANK2 ANK3

3.73e-05936229867141
Pubmed

Molecular self-avoidance in synaptic neurexin complexes.

NRXN1 NRXN2

3.73e-05936234919427
Pubmed

Expression of Phosphate Transporters during Dental Mineralization.

SLC34A2 SLC34A1

3.73e-05936228892649
Pubmed

PDZ-domain-mediated interaction of the Eph-related receptor tyrosine kinase EphB3 and the ras-binding protein AF6 depends on the kinase activity of the receptor.

NRXN1 NRXN2

3.73e-0593629707552
Pubmed

Cell organization, growth, and neural and cardiac development require αII-spectrin.

ANK2 ANK3

4.66e-051036222159418
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

BSN ANK2 ANK3 NRXN1 CNOT1 SHANK3 NUP153

5.05e-0596336728671696
Pubmed

Absence of alpha-syntrophin leads to structurally aberrant neuromuscular synapses deficient in utrophin.

DMD ANK3

5.70e-051136210995443
Pubmed

SPARCL1 Promotes Excitatory But Not Inhibitory Synapse Formation and Function Independent of Neurexins and Neuroligins.

NRXN1 NRXN2

5.70e-051136232973045
Pubmed

Behavioral phenotypes of genetic mouse models of autism.

NRXN1 SHANK3

5.70e-051136226403076
Pubmed

Inhibition of RIF1 by SCAI Allows BRCA1-Mediated Repair.

BSN NUP153

6.83e-051236228700933
Pubmed

Advancing the understanding of autism disease mechanisms through genetics.

NRXN1 SHANK3

8.07e-051336227050589
Pubmed

Pikachurin, a dystroglycan ligand, is essential for photoreceptor ribbon synapse formation.

DMD BSN

8.07e-051336218641643
Pubmed

Ankyrin-G induces nucleoporin Nup358 to associate with the axon initial segment of neurons.

ANK3 NUP153

8.07e-051336231427429
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

CBARP DMD ANK3 CTDSPL2 CNOT1 NUP153 PPP1R12B

8.64e-05104936727880917
Pubmed

The contribution of rare and common variants in 30 genes to risk nicotine dependence.

NRXN1 NRXN2

9.41e-051436225450229
Pubmed

TLR3 downregulates expression of schizophrenia gene Disc1 via MYD88 to control neuronal morphology.

NRXN1 SHANK3

9.41e-051436227979975
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

HAVCR1 MYADM ZMYM1 ANK3 CNOT1 INPP5B NUP153

1.06e-04108436711544199
Pubmed

Ankyrin-G regulated epithelial phenotype is required for mouse lens morphogenesis and growth.

ANK2 ANK3

1.08e-041536230562487
Pubmed

Elevated fibroblast growth factor 23 exerts its effects on placenta and regulates vitamin D metabolism in pregnancy of Hyp mice.

SLC34A2 SLC34A1

1.24e-041636224470103
Pubmed

Tissue distribution, ontogeny, and hormonal regulation of xenobiotic transporters in mouse kidneys.

SLC34A2 SLC34A1

1.24e-041636219679677
Pubmed

Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.

ANK2 ANK3 NRXN1 SHANK3

1.30e-0425136427507650
Pubmed

MEF2C regulates cortical inhibitory and excitatory synapses and behaviors relevant to neurodevelopmental disorders.

NRXN1 SHANK3

1.40e-041736227779093
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

CBARP BSN ANK2 ANK3 NRXN1 CNOT1 SHANK3

1.44e-04113936736417873
Pubmed

Kv7/KCNQ potassium channels in cortical hyperexcitability and juvenile seizure-related death in Ank2-mutant mice.

ANK2 ANK3

1.58e-041836237321992
InteractionANK2 interactions

ANK2 ANK3 SHANK3 PPP1R12B

2.18e-0598344int:ANK2
InteractionZAN interactions

ZAN SHANK3

2.75e-055342int:ZAN
InteractionRGS14 interactions

BSN ANK2 ANK3 SHANK3 PPP1R12B

4.82e-05240345int:RGS14
InteractionKCTD13 interactions

ARFGEF2 MYADM DMD BSN ANK2 ANK3 NRXN2 CNOT1 SHANK3 PPP1R12B

6.85e-0513943410int:KCTD13
GeneFamilyCD molecules|Mucins

MUC16 MUC5B MUC22 MUC17

2.32e-0821274648
GeneFamilyAnkyrin repeat domain containing

ANK2 ANK3 SHANK3 PPP1R12B

4.31e-04242274403
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HSERT

AFF2 ANK2 NRXN1 NRXN2 SHANK3 SEZ6

3.12e-05450366M39072
CoexpressionHEVNER_CORTICAL_PLATE_POSTMITOTIC_NEURONS

BSN ANK2 ANK3 SEZ6

3.59e-05136364MM407
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HNBML5

AFF2 BSN ANK2 ANK3 NRXN1 NRXN2

3.74e-05465366M39066
CoexpressionNABA_ECM_AFFILIATED

MUC16 MUC5B MUC22 MUC17

8.56e-05170364M5880
CoexpressionHU_FETAL_RETINA_AMACRINE

ANK3 NRXN1 LHX9

9.36e-0564363M39261
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

HCFC2 AFF2 BSN ANK2 ANK3 NRXN1 NRXN2 SHANK3

1.03e-041106368M39071
CoexpressionGSE28783_ANTI_MIR33_VS_CTRL_ATHEROSCLEROSIS_MACROPHAGE_DN

ARFGEF2 AFF2 SMPDL3A NUP153

1.54e-04198364M8355
CoexpressionGSE22025_UNTREATED_VS_PROGESTERONE_TREATED_CD4_TCELL_UP

CBARP BSN ANK2 INPP5B

1.54e-04198364M8377
CoexpressionAtlasFacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_2500_k-means-cluster#5

TET2 HCFC2 DMD ANK2 NRXN1 NRXN2 INPP5B

9.12e-05688347Facebase_RNAseq_e10.5_Mandibular Arch_2500_K5
CoexpressionAtlasFacebaseRNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_2500_k-means-cluster#4

TET2 HCFC2 DMD ANK2 NRXN1 NRXN2 INPP5B

1.22e-04721347Facebase_RNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_2500_K4
CoexpressionAtlasFacebaseRNAseq_e9.5_Facial Mesenchyne_top-relative-expression-ranked_2500_k-means-cluster#5

TET2 HCFC2 DMD ANK2 NRXN1 NRXN2 INPP5B

1.23e-04722347Facebase_RNAseq_e9.5_Facial Mesenchyne_2500_K5
CoexpressionAtlasFacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_2500_k-means-cluster#3

TET2 HCFC2 DMD ANK2 NRXN1 NRXN2 INPP5B

1.32e-04730347Facebase_RNAseq_e8.5_Paraxial Mesoderm_2500_K3
CoexpressionAtlasFacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#5

TET2 HCFC2 DMD ANK2 NRXN1 NRXN2 INPP5B

1.34e-04732347Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_2500_K5
CoexpressionAtlasFacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_2500_k-means-cluster#5

TET2 HCFC2 DMD ANK2 NRXN1 NRXN2 INPP5B

1.47e-04743347Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_2500_K5
CoexpressionAtlasFacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#2

TET2 HCFC2 DMD ANK2 NRXN1 NRXN2 INPP5B

1.52e-04747347Facebase_RNAseq_e9.5_Maxillary Arch_2500_K2
CoexpressionAtlasFacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_2500_k-means-cluster#2

TET2 HCFC2 DMD ANK2 NRXN1 NRXN2 INPP5B

1.52e-04747347Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_2500_K2
CoexpressionAtlasDevelopingKidney_e15.5_Cap mesenchyme_emap-27738_k-means-cluster#5_top-relative-expression-ranked_500

ARFGEF2 ANK3 CTDSPL2

2.63e-0478343gudmap_developingKidney_e15.5_Cap mesenchyme_500_k5
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MUC5B DMD ZAN NRXN1 MROH2A

3.68e-07184365ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MUC5B DMD ZAN NRXN1 MROH2A

3.68e-071843652cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MUC5B DMD ZAN NRXN1 MROH2A

3.68e-071843652b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Neuronal-Cortical_neuron|10w / Sample Type, Dataset, Time_group, and Cell type.

ANK2 ANK3 NRXN1 NRXN2 LHX9

5.56e-0720036568c90376e2779434e4ad8dc6dd3b44baa700e2f4
ToppCellnucseq-Epithelial-Epithelial_Glandular|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MUC16 MUC5B MUC17 MGAM2

1.29e-05179364859cd8ee414ad6207c046ada2e655e49322dd01c
ToppCellwk_15-18-Epithelial-PNS-KCNIP4+_neuron|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

BSN ANK2 NRXN1 SEZ6

1.29e-05179364e20bfdfb6d5af8556eb66b81a19fbe4e3e28334a
ToppCellnucseq-Epithelial-Epithelial_Glandular-Goblet|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MUC16 MUC5B MUC17 MGAM2

1.32e-051803643dc80bc636bf0e6ffc9762853132a9fe59fd1f66
ToppCellnucseq-Epithelial-Epithelial_Glandular-Goblet-Goblet|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MUC16 MUC5B MUC17 MGAM2

1.32e-05180364668a2d8e1d5a390309d5eb62c836f5903144bea9
ToppCellControl-Epithelial_cells-Airway_mucous|Control / group, cell type (main and fine annotations)

MUC16 MUC5B MUC17 MGAM2

1.41e-0518336415d24a4fb1ffe6cbafbd54fcd7dde9ddcfbe03b2
ToppCell3'-Adult-SmallIntestine-Epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC5A11 SLC34A2 MUC17 MGAM2

1.44e-05184364ed7a8e79e5723a5f5a03f542203d9e50bdef5f50
ToppCellLV-15._Ventricular_Cardiomyocyte_III|LV / Chamber and Cluster_Paper

DMD ANK2 ANK3 PPP1R12B

1.44e-05184364ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCellControl-Epithelial_cells-Airway_goblet|Control / group, cell type (main and fine annotations)

MUC16 MUC5B MUC17 MGAM2

1.44e-05184364d92a71441e4e19f8c301999d8186f8e48e3cd162
ToppCellLV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

DMD ANK2 ANK3 PPP1R12B

1.47e-051853646baccb26f999145e51b91d94315bf8d4655bef31
ToppCell5'-Adult-LargeIntestine-Neuronal-Glial_mature|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DMD ANK2 ANK3 NRXN1

1.47e-05185364f607b6ee579562e2f92103fa5c7053df0170a229
ToppCell5'-Adult-LargeIntestine-Neuronal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DMD ANK2 ANK3 NRXN1

1.47e-05185364317f2c854f00aa5957319b818c85eeed7d72ec7f
ToppCell5'-Adult-LargeIntestine-Neuronal-Glial_mature-Adult_Glia|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DMD ANK2 ANK3 NRXN1

1.47e-051853647bb8fdfe04f85d25056380ec58222366de323a21
ToppCellLA-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

DMD ANK2 ANK3 PPP1R12B

1.57e-051883646d249fe92d51a19da19ec14bb2262d394255d577
ToppCellRV-06._Ventricular_Cardiomyocyte_II|RV / Chamber and Cluster_Paper

DMD ANK2 ANK3 PPP1R12B

1.63e-05190364fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCellLV-06._Ventricular_Cardiomyocyte_II|LV / Chamber and Cluster_Paper

DMD ANK2 ANK3 PPP1R12B

1.67e-0519136425f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCellLA-03._Atrial_Cardiomyocyte|LA / Chamber and Cluster_Paper

DMD ANK2 ANK3 PPP1R12B

1.67e-051913645d1b674eb7703830b7ce8bbeac3363cabd0e6ae9
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CBARP BSN NRXN2 SEZ6

1.74e-05193364be28070c049e7cb68bcd54f582226eb2f5e4bc1c
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CBARP BSN NRXN2 SEZ6

1.74e-051933640c652ebe22ce5d2927599dd97ef1920547858395
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CBARP BSN NRXN2 SEZ6

1.74e-051933648689a70a33a7c3823dc647d41ac0160e7c3ae396
ToppCellCOVID-19-Heart-CM_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

DMD ANK2 ANK3 PPP1R12B

1.74e-05193364dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCell21-Trachea-Epithelial-Epithelial|Trachea / Age, Tissue, Lineage and Cell class

ANK2 NRXN1 NRXN2 MUC17

1.74e-051933649a8bb44a37f3202e3123a6680bd5545dc91a6d40
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_Prolif-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NRXN1 NRXN2 CTDSPL2 SON

1.77e-051943647a66bd7d4fc9c6db861cedd2487f241e406869d1
ToppCellRA-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

DMD ANK2 ANK3 PPP1R12B

1.77e-0519436489812fb164065041357bb37a3c2d87028ec3de4e
ToppCellRA-03._Atrial_Cardiomyocyte|RA / Chamber and Cluster_Paper

DMD ANK2 ANK3 PPP1R12B

1.77e-05194364c3535f7cc0076653c72db582047cff053c322397
ToppCellCOVID-19-Heart-CM_1|Heart / Disease (COVID-19 only), tissue and cell type

DMD ANK2 ANK3 PPP1R12B

1.81e-05195364f1ef50331eda8f1239dba6ea970df4eaccf032f1
ToppCellBronchial-10x5prime-Epithelial-Epi_submucosal-gland-SMG_Duct|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MUC16 SLC34A2 MUC5B BSN

1.81e-05195364fc2a1d84b3d013e5cb9e7b9cdd740e4010897d20
ToppCellCOVID-19-Heart-CM_2|Heart / Disease (COVID-19 only), tissue and cell type

DMD ANK2 ANK3 PPP1R12B

1.81e-0519536475fc81bddb246dca3b437fb60827b1d4fe416405
ToppCellfacs-Thymus-Thymus_Epithelium|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMD ANK2 NRXN2 MROH2A

1.84e-051963646bc1187dfc4860a4e09032d7ea87ba3d9fe9f363
ToppCellfacs-Thymus-Thymus_Epithelium-18m|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMD ANK2 NRXN2 MROH2A

1.84e-05196364c8c89e469402e11aa2a9561e859b6fd1fb66c39b
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_monocytic-monocyte|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DMD ANK2 ANK3 NRXN1

1.88e-05197364b2f4d7c301c0b24003374923b31d6d058e40b213
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal-midbrain/hindbrain_cells|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

ANK2 ANK3 NRXN1 LHX9

1.88e-05197364c7078f6fcf27319ba8c5ebe700bcae7f1e7e39c1
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal-6|World / Primary Cells by Cluster

BPTF ANK2 ANK3 NRXN1

1.96e-051993641b1bccf4293f11048709d15a3c892c0edf3da3d2
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

DMD ANK3 NRXN2 PPP1R12B

1.96e-051993646b3a0e5d52a30d0eed30e6a670f5b53bc233f70c
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal|World / Primary Cells by Cluster

BPTF ANK2 ANK3 NRXN1

1.96e-051993644bee94c116c0da5eba951cb4cea7cc9dcdd6e30f
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Neuronal|10w / Sample Type, Dataset, Time_group, and Cell type.

ANK2 ANK3 NRXN1 NRXN2

2.00e-05200364979258173b82f37aeaaedd53b4a527da1dbe1b80
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-Neuronal|2m / Sample Type, Dataset, Time_group, and Cell type.

ANK3 NRXN1 LHX9 SEZ6

2.00e-0520036460b86c4a4e247b2673d31b085b440a6e574393bb
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-Neuronal-Cortical_neuron|2m / Sample Type, Dataset, Time_group, and Cell type.

ANK3 NRXN1 LHX9 SEZ6

2.00e-05200364db2dbd31dd02c0d1c1070ed5548ce949227e4775
ToppCellBronchus_Control_(B.)-Epithelial-TX|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

MUC16 SLC34A2 MUC5B ANK3

2.00e-05200364f5bc7d30aa03dd0f95eb64255bd1a2543be8d327
ToppCellFrontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Reln_(Cajal-Retzius)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

SLC5A11 MROH2A LHX9

1.12e-041163631bfd3b0ec4cb5a04c6dfe7861a544eb277e473a3
ToppCellFrontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Reln_(Cajal-Retzius)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

SLC5A11 MROH2A LHX9

1.12e-04116363a3dcd18807d14e207438f321be62797384fd3907
ToppCellBronchial-10x5prime-Stromal-Schwann-Schwann_nonmyelinating|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ANK2 ANK3 NRXN1

1.12e-04116363b0a3c109c5f20ab699e53bf8ab3903d102f5f315
ToppCellFrontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

SLC5A11 MROH2A LHX9

1.12e-04116363685484ea4cbefb5aff5f0cd999fdfadc5a5676e1
ToppCellRV-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

DMD PPP1R12B GABRR3

1.30e-041223631cb1dd03b2aaedbe04f3ed907568c3b7f54767b3
ToppCellLA-10._Endothelium_II|LA / Chamber and Cluster_Paper

NRXN1 SHANK3 GABRR3

1.72e-04134363048fa6ccf305d22d9a53db4ab385f39f558010d8
ToppCellPBMC-Control-Hematopoietic-Platelet-Platelet-plt_5|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MUC16 MUC22 SLC34A1

1.79e-0413636327a41463e6f16deb5b1d4f17fefded9959038c07
ToppCellPBMC-Control-Hematopoietic-Platelet-Platelet-plt_5|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MUC16 MUC22 SLC34A1

1.79e-0413636388b5c839d0446c6d6b7e81fc4d48f5e7e96eea11
ToppCellP15-Epithelial-epithelial_progenitor_cell-epithelial_progenitor_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SLC34A2 MUC5B ANK3

2.25e-04147363aba44c7057096483c4293a7ebcf8ccc8baed0231
ToppCellLA-15._Ventricular_Cardiomyocyte_III|LA / Chamber and Cluster_Paper

DMD ANK3 PPP1R12B

2.25e-041473638970eb6b82589f39439c61a57d999661ec8342de
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_Peritubular_Capilary_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MUC16 MYADM MGAM2

2.25e-04147363c8e5bdc3538089acd35a4b41390afaec0ac6d1aa
ToppCellP15-Epithelial-epithelial_progenitor_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SLC34A2 MUC5B ANK3

2.49e-0415236300d5503d462cfa009fb4cac79ecee11725a18b9a
ToppCellPND01-03-samps-Mesenchymal-Pericyte|PND01-03-samps / Age Group, Lineage, Cell class and subclass

ZAN NRXN1 SLC34A1

2.49e-04152363fc9472bc19f997103da535b035105f01429cb08e
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MUC16 SLC34A2 HAVCR1

2.54e-04153363499670e716fc85ce76630fc813cec86f8419f2a1
ToppCellTCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

SLC5A11 HAVCR1 SLC34A1

2.58e-0415436389a60a79d07466d7ad05888d10a72d3b1ab384af
ToppCellTCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal-Connective_tissue_normal|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

SLC5A11 HAVCR1 SLC34A1

2.58e-04154363f1fea1a87e977221fa125b62287368be9af4987d
ToppCellTCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal-Connective_tissue_normal-Connective_tissue_normal|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

SLC5A11 HAVCR1 SLC34A1

2.58e-04154363b5604c0b0b9b283352a3f612f40883b9123475d1
ToppCellTCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal-Connective_tissue_normal-Connective_tissue_normal-1|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

SLC5A11 HAVCR1 SLC34A1

2.58e-04154363160b170a3ade8b246843c9854af332475c047ba0
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 MUC5B ANK3

2.73e-04157363c43f2e1ea53b375a7432f17f87cfef3b2261003d
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-Tregs|GI_small-bowel / Manually curated celltypes from each tissue

SLC5A11 HAVCR1 AFF2

2.73e-04157363c44bd530e396b08f16f284e185dcb830843959ea
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal-ventral_progenitors_and_neurons_1|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

ANK2 ANK3 NRXN1

3.16e-041653639795ce31689bc63f5a2d68725ef00b23a90c3846
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ZAN NRXN1 SLC34A1

3.28e-041673633edb0570e583bb527165bcd8a4c25a042054043b
ToppCell3'-Adult-SmallIntestine-Epithelial-epithelial_progenitor_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC34A2 MUC17 MGAM2

3.34e-041683634e2e4c88ada772e9ba6e72c9ae3a05c063e93318
ToppCellCOVID-19-Heart-Neuronal|COVID-19 / Disease (COVID-19 only), tissue and cell type

ANK2 ANK3 NRXN1

3.34e-0416836388c2c574f428c2502b5fe099bd73b0758f668ef6
ToppCell3'-Adult-SmallIntestine-Epithelial-epithelial_progenitor_cell-TA|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC34A2 MUC17 MGAM2

3.34e-04168363ee4dab089adef2f47a9d39d91934523331a8b81c
ToppCellTCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-5|TCGA-Bladder / Sample_Type by Project: Shred V9

BSN NRXN1 SEZ6

3.39e-041693639c4e83fe8225d16173a103bf5a57b17d623be923
ToppCell3'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Glia_3_(BCAN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DMD NRXN1 NRXN2

3.39e-041693632456b3e7776e8a2214972be1b4d66a3ca5480ae0
ToppCelldroplet-Liver-LIVER-NPC-1m-Lymphocytic-macrophage/monocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HCFC2 CTDSPL2 PPP1R12B

3.45e-041703633ad9f950b87ee98f025ab9b4a8ed551e6a9b4764
ToppCelldroplet-Limb_Muscle-nan-21m-Lymphocytic-B_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC34A2 HAVCR1 SLC34A1

3.57e-0417236362734d231290ca725276dc62faa2ac87bd1b37b8
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DMD AFF2 NRXN1

3.57e-0417236303a0aff6b7971093a4347b5ed12546d78374c56f
ToppCelldroplet-Thymus-nan-21m-Lymphocytic-B_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HAVCR1 MYADM SLC34A1

3.63e-041733630a0cd40bb5f61431fe34758626c8a63ec610a8a5
ToppCelldroplet-Lung-nan-21m-Myeloid-Proliferating_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HAVCR1 SLC34A1 NUP153

3.63e-041733632eb6e9fc3a3654f6f86fbd112e80a18814afd103
ToppCellCOVID-19-Heart-Neuronal|Heart / Disease (COVID-19 only), tissue and cell type

ANK2 ANK3 NRXN1

3.63e-041733636fb5f9e6536a5d57fd8e6657b494047a2d0bc9c7
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c08-IL2RB|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

HAVCR1 ANK3 LHX9

3.63e-041733635295ed31648abf8edff214cf67cd4769f20f9e6d
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AFF2 BSN NRXN1

3.70e-04174363f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MUC16 CBARP NRXN2

3.70e-041743634da79da7a09ee1e345102c5331675ebcdbe56171
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AFF2 NRXN1 SEZ6

3.88e-041773632b63f0529ef73e0eede9b7ef1f08b0a0426a9c82
ToppCellILEUM-inflamed-(9)_Enteric_neurons|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

ANK2 ANK3 NRXN1

3.95e-04178363d9142151819afb0dc22bfb32a9c9dba5f553067d
ToppCellfacs-Limb_Muscle-Muscle_Diaphragm-18m-Mesenchymal-skeletal_muscle_satellite_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC34A2 ANK3 SON

3.95e-0417836356b19f9c9585538fb8a4c3eea2d132b254cf11ef
ToppCell(5)_Glands_mucous|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

MUC16 SLC34A2 MUC5B

3.95e-04178363f0f19b0d78f2cc5df4d4c321a953a6e447d5114a
ToppCellILEUM-inflamed-(9)_Neuro_cell|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

ANK2 ANK3 NRXN1

3.95e-04178363611504b0a9e6318b18fba83787b03f9245c82252
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 MUC5B ANK3

4.01e-041793636e965e424eebef50f0202cff75f458be395cfca1
ToppCell(5)_Epithelial_cells-(5)_Glands_mucous|(5)_Epithelial_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

MUC16 SLC34A2 MUC5B

4.08e-04180363a4118adaf4b09e2ca01b662ed60e7bbf32a24d58
ToppCell5'-Adult-SmallIntestine-Neuronal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ANK2 ANK3 NRXN1

4.08e-041803635e6e38ee0758ef2342a6a821c78ed24b57bb7b11
ToppCelldroplet-Lung-immune-endo-depleted-3m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AFF2 NRXN1 NRXN2

4.08e-041803630153667e44fdbc3c0d444dcb023069925a2b69a2
ToppCell5'-Adult-SmallIntestine-Neuronal-Glial_mature-Adult_Glia|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ANK2 ANK3 NRXN1

4.08e-04180363b88cd7ae922782176c057342d1b9eb9b8e5e7204
ToppCelldroplet-Lung-immune-endo-depleted-3m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AFF2 NRXN1 NRXN2

4.08e-0418036340a28b410f46215d6d7cf8a02a18078eb046b5b0
ToppCell5'-Adult-SmallIntestine-Neuronal-Glial_mature|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ANK2 ANK3 NRXN1

4.08e-04180363ebd6e719a03f25155fa8181be19469d04d6d10a6
ToppCell3'_v3-blood-Myeloid_Dendritic-pDC|blood / Manually curated celltypes from each tissue

DMD ZAN SHANK3

4.15e-0418136366d890a105f955dca91d6e5e6c730d1a68ee9233
ToppCell5'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Glia_2_(ELN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC34A2 NRXN1 NRXN2

4.15e-04181363098dbb3e0ff531c9720a233123250c1e39a97d4c
ToppCellPCW_10-12-Neuronal-Neuronal_postreplicative|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

DMD ANK2 NRXN1

4.15e-041813631aebb62ed4439db444ee9d30688212b86ee3d9ef
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

SLC5A11 NRXN1 SLC34A1

4.15e-04181363c80ffa2ded5975a88e9a1a7d333196f95237bf0a
ToppCellPCW_10-12-Neuronal-Neuronal_postreplicative-neuro_NA|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

DMD ANK2 NRXN1

4.15e-041813636aee2ddee4790250ef3b2ef0038bd9839925c995
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC5A11 HAVCR1 SLC34A1

4.15e-041813639542c19edc9bd2cba68c01c2a8407705398e3011
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC5A11 HAVCR1 SLC34A1

4.15e-041813638f04f8cac5d705dc5f6cf6f4516d6e45b0aa4ae5
ToppCellPCW_10-12-Neuronal|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

DMD ANK2 NRXN1

4.15e-04181363381b553e2cae65ce6be100662a5f9f963353840c
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC5A11 HAVCR1 SLC34A1

4.21e-04182363e1e58176f533092b6b974ca1ce8b02192a6e193d
ToppCellEpithelial-lung_neuroendocrine_cell_(PNEC)|World / Lineage, Cell type, age group and donor

BSN ANK2 NRXN1

4.21e-0418236357bf4ffb304324e2e392e196336a530d9f78fe0d
ComputationalNeighborhood of RTN1

ANK2 NRXN1 NRXN2

1.77e-0452233GNF2_RTN1
DrugO,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate

BPTF ANK3 NRXN1 NRXN2 SHANK3

1.46e-05211345ctd:C009618
Drugenzacamene

BSN NRXN1 NRXN2 SHANK3

4.00e-05129344ctd:C038939
Drugoctylmethoxycinnamate

BSN NRXN1 NRXN2 SHANK3

5.35e-05139344ctd:C118580
Drugnalidixic acid

SLC34A2 AFF2 ANK2 ANK3 SLC34A1

5.36e-05277345CID000004421
Drugarsenic pentoxide

SLC34A2 SLC34A1

6.03e-058342ctd:C042120
Drug3-doxylandrostanol

ANK2 ANK3

7.74e-059342CID000189075
Drugbutylparaben

BSN NRXN1 NRXN2 SHANK3

8.59e-05157344ctd:C038091
DrugC7 5

SLC34A2 SLC34A1

9.67e-0510342CID004248455
DrugAC1NSPXR

ANK2 ANK3

1.18e-0411342CID005313815
Drug26-nor-25-doxylcholestanol

ANK2 ANK3

1.18e-0411342CID000125890
Drug20,25-diazacholesterol

ANK2 ANK3

1.18e-0411342CID000009402
DiseaseSemantic-Pragmatic Disorder

NRXN1 SHANK3

7.90e-0511362C0454655
DiseaseAuditory Processing Disorder, Central

NRXN1 SHANK3

7.90e-0511362C0751257
DiseaseLanguage Delay

NRXN1 SHANK3

7.90e-0511362C0023012
DiseaseLanguage Development Disorders

NRXN1 SHANK3

7.90e-0511362C0023014
DiseaseSpeech Delay

NRXN1 SHANK3

7.90e-0511362C0241210
DiseaseAutism Spectrum Disorders

NRXN1 NRXN2 SHANK3

1.54e-0485363C1510586
DiseaseSchizophrenia

NRXN1 SHANK3

2.19e-0418362cv:C0036341
DiseaseAlzheimer disease, educational attainment

ARFGEF2 TET2 BSN NRXN1

2.29e-04247364EFO_0011015, MONDO_0004975
Diseasechronic kidney disease (biomarker_via_orthology)

HAVCR1 SLC34A1

5.36e-0428362DOID:784 (biomarker_via_orthology)
Diseasemetabolite measurement

BPTF ZMYM1 DMD ANK3 SLC34A1

5.61e-04560365EFO_0004725
Diseaseresponse to aromatase inhibitor

MUC16 CNOT1

7.01e-0432362GO_0061477
Diseaseanti-GAD65 autoimmune neurological syndromes

ZAN MUC22

8.40e-0435362EFO_0803379
Diseaseautism spectrum disorder (implicated_via_orthology)

NRXN1 NRXN2 SHANK3

8.45e-04152363DOID:0060041 (implicated_via_orthology)
Diseasesex interaction measurement, Crohn's disease

BSN MUC22

9.38e-0437362EFO_0000384, EFO_0008343
DiseaseProteinuria

MUC16 HAVCR1

1.27e-0343362C0033687
Diseaseforced expiratory volume, response to bronchodilator

TET2 SLC34A2 NRXN1 NRXN2

2.05e-03445364EFO_0004314, GO_0097366
DiseaseNecrosis

HAVCR1 DMD

2.06e-0355362C0027540
DiseaseIntellectual Disability

BPTF NRXN1 NRXN2 SHANK3

2.09e-03447364C3714756
Diseasetriglycerides in LDL measurement

BPTF HAVCR1

2.14e-0356362EFO_0022320

Protein segments in the cluster

PeptideGeneStartEntry
TMATAATTTTTTTAT

CBARP

6

Q8N350
MEQVDEITTSTTTST

CTDSPL2

181

Q05D32
TTISTITSTITTGLM

AFF2

1021

P51816
TSMESTVSSGTQTTV

ARFGEF2

616

Q9Y6D5
LTQTTVMETVTTVTT

DMD

676

P11532
ITEVTTMTSTVATES

BPTF

1711

Q12830
VLTTTTTTVATGSMA

MUC5B

2661

Q9HC84
VLTTTTTTVATGSMA

MUC5B

3361

Q9HC84
VLTTTTTTVATGSMA

MUC5B

4651

Q9HC84
VTEEVTTTTTTITEK

ANK2

816

Q01484
NVTTSTMEDTTISRS

MUC16

4861

Q8WXI7
KTESTEMTITTQTGS

MUC16

9071

Q8WXI7
MVTSLVTSSRAVTST

MUC16

11151

Q8WXI7
EMSTSIMETTTTLAT

NRXN1

311

P58400
TSVSSTVSSTQTMVT

HCFC2

511

Q9Y5Z7
TMVIDATVTTTSTKD

MGAM2

2351

Q2M2H8
IISETTMASTTGSET

MUC22

171

E2RYF6
TMASTTGSETATVST

MUC22

176

E2RYF6
KVITASSMSSETTVA

MUC22

246

E2RYF6
TTTVSITGTETTMVS

MUC22

356

E2RYF6
TTTCTEGSEMTAVST

MUC22

666

E2RYF6
TAVSATGSEMTTVST

MUC22

766

E2RYF6
TTTSTEGSEMTTVST

MUC22

806

E2RYF6
TTVSTTDSETTMVST

MUC22

896

E2RYF6
TMVSTTGSERTITST

MUC22

906

E2RYF6
TTVTTMGSETTTAST

MUC22

1216

E2RYF6
TTASTTGSEMTTVFT

MUC22

1386

E2RYF6
TGSEMTTVFTTVSET

MUC22

1391

E2RYF6
STDTVINVITNMTTT

SMPDL3A

121

Q92484
LATATTVSITMASSV

BSN

1726

Q9UPA5
TVVTSVTSNMDSHES

LHX9

371

Q9NQ69
MPVTVTRTTITTTTT

MYADM

1

Q96S97
EMSTSIMETTTTLAT

NRXN1

1316

Q9ULB1
QSSSTSTSIIVSMVS

SLC34A1

161

Q06495
ATTIMETTTTMATTT

NRXN2

316

P58401
FSMVASSVTTTESIK

FAM189B

51

P81408
TVLTMSTIITAVSAS

GABRR3

306

A8MPY1
KIVTEETMTTTTVTE

ANK3

816

Q12955
SEITDMVRSSTITVS

INPP5B

296

P32019
ITSMSVSTTLVASSE

MUC17

631

Q685J3
TTMVASSETSTLSTT

MUC17

1051

Q685J3
DTVKIITSSVSGMTT

MROH2A

506

A6NES4
TTVLTTMTVSTTTSV

HAVCR1

176

Q96D42
MILSTVTLITVSTVS

SLC5A11

526

Q8WWX8
VSTMVTTSTTTTVAK

CNOT1

1036

A5YKK6
LVQSSSTSTSIVVSM

SLC34A2

156

O95436
STSTSIVVSMVSSSL

SLC34A2

161

O95436
ETTSTISTVSSMSTL

SHANK3

1371

Q9BYB0
DEETTTTTTIITTTI

SEZ6

221

Q53EL9
TVVSESAETMTASSS

NUP153

761

P49790
MESSSVSVVSVVHDT

ZMYM1

316

Q5SVZ6
LAERTMSVTTDSTVT

TET2

1971

Q6N021
QSVVTTSELSTMTVS

SON

656

P18583
TEETTTSVEETTIST

ZAN

826

Q9Y493
ESSETTTNTTTAKEM

PPP1R12B

761

O60237