Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionphosphopyruvate hydratase activity

ENO1 ENO2 ENO3

4.11e-0642033GO:0004634
GeneOntologyMolecularFunctionextracellular matrix structural constituent

IMPG1 HMCN2 HSPG2 FRAS1 COL12A1 COL17A1 TGFBI HMCN1 VCAN MUC6

2.35e-0518820310GO:0005201
GeneOntologyCellularComponentphosphopyruvate hydratase complex

ENO1 ENO2 ENO3

3.64e-0642043GO:0000015
GeneOntologyCellularComponentbasement membrane

HMCN2 USH2A HSPG2 FRAS1 COL17A1 TGFBI HMCN1

1.98e-041222047GO:0005604
GeneOntologyCellularComponentexternal encapsulating structure

IMPG1 HMCN2 AGT USH2A HSPG2 FRAS1 COL12A1 COL17A1 COL20A1 PKHD1L1 TGFBI CELA3B CELA3A HMCN1 VCAN ADAMTS14 MUC6

2.63e-0465820417GO:0030312
GeneOntologyCellularComponentdistal axon

MAP1A PTPRF KCNC1 KCNC3 PTPRS USH2A MICAL1 PNMT BRSK2 SLC18A2 SMO ENO1 ENO2

3.64e-0443520413GO:0150034
GeneOntologyCellularComponentneuronal cell body

MAP1A STAU1 DLGAP3 HMCN2 PTPRF KCNC1 KCNC3 PTPRS VPS13A USH2A PNMT RTN4 ATP13A2 RGS12 MTOR SLC18A2 SMO WDFY3 ENO2

5.59e-0483520419GO:0043025
GeneOntologyCellularComponentextracellular matrix

IMPG1 HMCN2 AGT USH2A HSPG2 FRAS1 COL12A1 COL17A1 COL20A1 TGFBI CELA3B CELA3A HMCN1 VCAN ADAMTS14 MUC6

7.41e-0465620416GO:0031012
GeneOntologyCellularComponentcollagen-containing extracellular matrix

IMPG1 HMCN2 AGT USH2A HSPG2 FRAS1 COL12A1 COL17A1 COL20A1 TGFBI CELA3B CELA3A HMCN1 VCAN

7.42e-0453020414GO:0062023
GeneOntologyCellularComponentDNA helicase complex

BLM HELQ

9.30e-0452042GO:0033202
GeneOntologyCellularComponentsomatodendritic compartment

ABL2 MAP1A MARK3 ADCY9 STAU1 DLGAP3 HMCN2 PTPRF KCNC1 KCNC3 PTPRS VPS13A USH2A HTR1D PNMT RTN4 ATP13A2 RGS12 MTOR SLC18A2 MARK4 SMO WDFY3 ENO2

9.35e-04122820424GO:0036477
DomainIg-like_fold

IGFN1 BTNL8 MYCBP2 CADM4 PHYHIP TMEM81 FNDC1 FNDC7 HMCN2 PTPRF PTPRS NFKB2 USH2A PLXNA1 HSPG2 COL12A1 CD300LF COL20A1 MYOM3 RELA VSTM2B ADGRA2 PKHD1L1 HMCN1 VCAN IL4R

4.02e-0870620026IPR013783
Domain-

IGFN1 BTNL8 MYCBP2 CADM4 PHYHIP TMEM81 FNDC1 FNDC7 PTPRF PTPRS NFKB2 USH2A PLXNA1 HSPG2 COL12A1 CD300LF COL20A1 MYOM3 RELA VSTM2B ADGRA2 PKHD1L1 HMCN1 VCAN IL4R

4.77e-08663200252.60.40.10
DomainEnolase_N

ENO1 ENO2 ENO3

1.21e-0632003PF03952
DomainEnolase

ENO1 ENO2 ENO3

1.21e-0632003IPR000941
DomainEnolase_C

ENO1 ENO2 ENO3

1.21e-0632003IPR020810
DomainEnolase_N

ENO1 ENO2 ENO3

1.21e-0632003IPR020811
DomainEnolase_CS

ENO1 ENO2 ENO3

1.21e-0632003IPR020809
DomainEnolase_C

ENO1 ENO2 ENO3

1.21e-0632003PF00113
DomainDAPK1

DAPK2 DAPK1 DAPK3

1.21e-0632003IPR020676
DomainEnolase_N

ENO1 ENO2 ENO3

1.21e-0632003SM01193
DomainEnolase_C

ENO1 ENO2 ENO3

1.21e-0632003SM01192
DomainENOLASE

ENO1 ENO2 ENO3

1.21e-0632003PS00164
DomainMFS_dom

SLC17A2 SPNS1 UNC93A SLC22A20P SLC2A9 FLVCR2 SLC17A5 SLC17A1 SLC18A2 MFSD13A

1.83e-0613420010IPR020846
Domain-

ENO1 ENO2 ENO3

4.80e-06420033.30.390.10
Domain-

ENO1 ENO2 ENO3

4.80e-06420033.20.20.120
DomainEnolase_C-like

ENO1 ENO2 ENO3

4.80e-0642003IPR029065
DomainEnolase_N-like

ENO1 ENO2 ENO3

4.80e-0642003IPR029017
DomainFN3

IGFN1 PHYHIP FNDC1 FNDC7 PTPRF PTPRS USH2A COL12A1 COL20A1 MYOM3 IL4R

5.12e-0618520011SM00060
Domainfn3

IGFN1 PHYHIP FNDC1 FNDC7 PTPRF PTPRS USH2A COL12A1 COL20A1 MYOM3

9.98e-0616220010PF00041
DomainFN3

IGFN1 PHYHIP FNDC1 FNDC7 PTPRF PTPRS USH2A COL12A1 COL20A1 MYOM3 IL4R

1.03e-0519920011PS50853
DomainFN3_dom

IGFN1 PHYHIP FNDC1 FNDC7 PTPRF PTPRS USH2A COL12A1 COL20A1 MYOM3 IL4R

1.62e-0520920011IPR003961
DomainMFS

SLC17A2 SPNS1 SLC22A20P SLC2A9 FLVCR2 SLC17A5 SLC17A1 SLC18A2

2.12e-051082008PS50850
DomainVWFA

ITGB3 HMCN2 VWA3A COL12A1 COL20A1 HMCN1 CACNA2D3

2.80e-05822007PS50234
DomainVWA

ITGB3 HMCN2 VWA3A COL12A1 COL20A1 HMCN1 CACNA2D3

3.28e-05842007SM00327
DomainVWF_A

ITGB3 HMCN2 VWA3A COL12A1 COL20A1 HMCN1 CACNA2D3

9.42e-05992007IPR002035
DomainZF_CCHC_HIVEP

HIVEP1 HIVEP3

1.14e-0422002PS51811
Domain-

ITGB3 VWA3A COL12A1 COL20A1 HMCN1 CACNA2D3

1.41e-047420063.40.50.410
DomainMFS_1

SLC17A2 SPNS1 FLVCR2 SLC17A5 SLC17A1 SLC18A2

1.76e-04772006PF07690
DomainMFS

SLC17A2 SPNS1 FLVCR2 SLC17A5 SLC17A1 SLC18A2

1.76e-04772006IPR011701
DomainIPT

NFKB2 PLXNA1 RELA PKHD1L1

1.85e-04272004SM00429
DomainIG

IGFN1 BTNL8 CADM4 TMEM81 HMCN2 PTPRF PTPRS HSPG2 CD300LF MYOM3 VSTM2B ADGRA2 HMCN1 VCAN

1.86e-0442120014SM00409
DomainIg_sub

IGFN1 BTNL8 CADM4 TMEM81 HMCN2 PTPRF PTPRS HSPG2 CD300LF MYOM3 VSTM2B ADGRA2 HMCN1 VCAN

1.86e-0442120014IPR003599
DomainEGF_CA

FAT2 HEG1 HMCN2 HSPG2 CUBN HMCN1 VCAN

3.45e-041222007SM00179
DomainIPT

NFKB2 PLXNA1 RELA PKHD1L1

3.63e-04322004IPR002909
DomainEGF-like_Ca-bd_dom

FAT2 HEG1 HMCN2 HSPG2 CUBN HMCN1 VCAN

3.80e-041242007IPR001881
DomainLaminin_G

FAT2 USH2A HSPG2 COL12A1 COL20A1

3.87e-04582005IPR001791
DomainSEA

IMPG1 HSPG2 MUC16

4.04e-04142003SM00200
DomainEGF

ITGB3 FAT2 HEG1 HSPG2 CUBN HMCN1 VCAN

4.19e-041262007PF00008
DomainGPCR_2_secretin-like

ADGRG4 FZD9 ADGRA2 ADGRG2 SMO

4.54e-04602005IPR000832
DomainGPCR_2-like

ADGRG4 FZD9 ADGRA2 ADGRG2 SMO

4.54e-04602005IPR017981
DomainG_PROTEIN_RECEP_F2_4

ADGRG4 FZD9 ADGRA2 ADGRG2 SMO

4.90e-04612005PS50261
Domain-

ADGRG4 FAT2 USH2A HSPG2 COL12A1 WDFY3

5.51e-049520062.60.120.200
DomainG2F

HMCN2 HMCN1

6.75e-0442002PF07474
DomainMARK/par1

MARK3 MARK4

6.75e-0442002IPR033624
DomainNIDOGEN_G2

HMCN2 HMCN1

6.75e-0442002PS50993
DomainK_chnl_volt-dep_Kv3

KCNC1 KCNC3

6.75e-0442002IPR003974
DomainGFP

HMCN2 HMCN1

6.75e-0442002IPR009017
DomainG2_nidogen/fibulin_G2F

HMCN2 HMCN1

6.75e-0442002IPR006605
DomainIG_LIKE

IGFN1 BTNL8 CADM4 TMEM81 HMCN2 PTPRF PTPRS HSPG2 CD300LF MYOM3 VSTM2B ADGRA2 HMCN1 VCAN

8.59e-0449120014PS50835
DomainCa/CaM-dep_Ca-dep_prot_Kinase

MARK3 DAPK2 DAPK3 BRSK2 MARK4

8.64e-04692005IPR020636
DomainIg_I-set

IGFN1 CADM4 HMCN2 PTPRF PTPRS HSPG2 MYOM3 HMCN1

1.04e-031902008IPR013098
DomainI-set

IGFN1 CADM4 HMCN2 PTPRF PTPRS HSPG2 MYOM3 HMCN1

1.04e-031902008PF07679
DomainIg-like_dom

IGFN1 BTNL8 CADM4 TMEM81 HMCN2 PTPRF PTPRS HSPG2 CD300LF MYOM3 VSTM2B ADGRA2 HMCN1 VCAN

1.08e-0350320014IPR007110
DomainKA1

MARK3 MARK4

1.12e-0352002PF02149
DomainIPT_NFkappaB

NFKB2 RELA

1.12e-0352002IPR033926
DomainKA1_dom

MARK3 MARK4

1.12e-0352002IPR001772
DomainRHD_CS

NFKB2 RELA

1.12e-0352002IPR030492
DomainKA1

MARK3 MARK4

1.12e-0352002PS50032
Domain-

MARK3 MARK4

1.12e-03520023.30.310.80
DomainEGF-like_dom

IMPG1 FAT2 HEG1 HMCN2 HSPG2 FRAS1 CUBN HMCN1 VCAN

1.49e-032492009IPR000742
DomainSEA

IMPG1 HSPG2 MUC16

1.60e-03222003PF01390
DomainEGF_1

ITGB3 FAT2 HEG1 HMCN2 USH2A HSPG2 CUBN HMCN1 VCAN

1.76e-032552009PS00022
DomainSEA

IMPG1 HSPG2 MUC16

1.83e-03232003PS50024
DomainSEA_dom

IMPG1 HSPG2 MUC16

1.83e-03232003IPR000082
DomainAPC_su10/DOC_dom

MYCBP2 HERC2

2.31e-0372002IPR004939
DomainDOC

MYCBP2 HERC2

2.31e-0372002PS51284
DomainKA1/Ssp2_C

MARK3 MARK4

2.31e-0372002IPR028375
DomainANAPC10

MYCBP2 HERC2

2.31e-0372002PF03256
DomainAPC10

MYCBP2 HERC2

2.31e-0372002SM01337
DomainConA-like_dom

BTNL8 ADGRG4 FAT2 USH2A HSPG2 COL12A1 COL20A1 WDFY3

2.54e-032192008IPR013320
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

MYCBP2 PFAS MBD6 ARHGEF11 ADCY9 HEG1 PTPRF PTPRS NFKB2 MLLT6 HERC2 MCF2L PLXNA1 ABCC10 HSPG2 FRAS1 DOCK9 AOC2 HECTD4 MYOM3 ADGRA2 ATP13A2 KCNH3 HIVEP3 ARAP3 TRIB3 MTOR FURIN MARK4 WDFY3 IL4R RAB11FIP3

1.09e-1311052053235748872
Pubmed

The death-associated protein kinases: structure, function, and beyond.

DAPK2 DAPK1 DAPK3

2.02e-073205316756490
Pubmed

The role of STAT3/mTOR-regulated autophagy in angiotensin II-induced senescence of human glomerular mesangial cells.

STAT3 AGT MTOR

2.02e-073205330389500
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

CCDC8 CTNNAL1 MYCBP2 TRPS1 DAPK3 PFAS ADCY9 BLM PTPRF PTPRS VPS13A HERC2 RELA NIBAN2 ARHGAP5 FAM171A2 WDR11 SLC4A1AP AIFM1 KCTD3 UBR3 SSH2

3.05e-0710492052227880917
Pubmed

A Moonlighting Human Protein Is Involved in Mitochondrial Import of tRNA.

ENO1 ENO2 ENO3

8.04e-074205325918939
Pubmed

Interferon induces NF-kappa B-inducing kinase/tumor necrosis factor receptor-associated factor-dependent NF-kappa B activation to promote cell survival.

NFKB2 MAP3K14 RELA

8.04e-074205316009713
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

CCDC8 HIVEP1 ABL2 MYCBP2 MARK3 DAPK2 DAPK3 STAT3 RUSC2 WDR62 MAP3K14 BRSK2 RGS12 FAM171A2 MTOR SLC25A1 MARK4 SSH2 PATJ

9.69e-078612051936931259
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

ENDOD1 MARK3 CADM4 DAPK1 ADCY9 PTPRF PLXNA1 COL17A1 EPB41L4B DOCK9 NIBAN2 RGS12 FAM171A2 MTOR PATJ

1.67e-065692051530639242
Pubmed

A new member of the I kappaB protein family, I kappaB epsilon, inhibits RelA (p65)-mediated NF-kappaB transcription.

NFKB2 NFKBIE RELA

2.00e-06520539315679
Pubmed

Genetic variation in the nuclear factor kappaB pathway in relation to susceptibility to rheumatoid arthritis.

NFKB2 NFKBIE MAP3K14 RELA

2.02e-0616205418434448
Pubmed

Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.

HSPG2 FRAS1 COL20A1 TGFBI HMCN1 VCAN

2.20e-0664205622261194
Pubmed

Roles of tau protein in health and disease.

MAP1A MARK3 BRSK2 MTOR MARK4

3.77e-0640205528386764
Pubmed

Cathepsin X cleaves the C-terminal dipeptide of alpha- and gamma-enolase and impairs survival and neuritogenesis of neuronal cells.

ENO1 ENO2 ENO3

3.98e-066205319433310
Pubmed

Control of RelB during dendritic cell activation integrates canonical and noncanonical NF-κB pathways.

NFKB2 NFKBIE RELA

3.98e-066205323086447
Pubmed

Expression of mouse dchs1, fjx1, and fat-j suggests conservation of the planar cell polarity pathway identified in Drosophila.

DCHS2 FAT2 DCHS1

6.94e-067205316059920
Pubmed

Hiv-1 Tat can substantially enhance the capacity of NIK to induce IkappaB degradation.

NFKB2 MAP3K14 RELA

6.94e-067205311511100
Pubmed

Leukocyte antigen-related protein tyrosine phosphatase negatively regulates hydrogen peroxide-induced vascular smooth muscle cell apoptosis.

STAT3 PTPRF ENO1

6.94e-067205318854310
Pubmed

Regulator of G protein signaling 12 drives inflammatory arthritis by activating synovial fibroblasts through MYCBP2/KIF2A signaling.

MYCBP2 HERC2 RGS12

6.94e-067205336700049
Pubmed

Molecular reclassification of Crohn's disease by cluster analysis of genetic variants.

IRGM STAT3 HERC2 DNAH12

9.51e-0623205420886065
Pubmed

Integral and associated lysosomal membrane proteins.

SPNS1 ABCC10 ATP13A2 SLC17A5 WDR11 MTOR ENPEP

1.04e-05126205717897319
Pubmed

Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinase.

NFKB2 NFKBIE RELA

1.11e-058205310195896
Pubmed

Nanog maintains pluripotency of mouse embryonic stem cells by inhibiting NFkappaB and cooperating with Stat3.

STAT3 NFKB2 RELA

1.65e-059205318223644
Pubmed

Genetic risk profiling and prediction of disease course in Crohn's disease patients.

IRGM STAT3 HERC2 DNAH12

2.15e-0528205419422935
Pubmed

Regulation of NF-κB by the p105-ABIN2-TPL2 complex and RelAp43 during rabies virus infection.

NFKB2 NFKBIE RELA

2.35e-0510205329084252
Pubmed

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.

HMCN2 AGT HSPG2 COL12A1 LCN2 TGFBI VCAN

2.71e-05146205727068509
Pubmed

Comparison of tear protein levels in breast cancer patients and healthy controls using a de novo proteomic approach.

MROH7 MCF2L LCN2 SSH2 ENO1 ENO2 ENO3

3.09e-05149205722664934
Pubmed

Common polymorphisms influencing serum uric acid levels contribute to susceptibility to gout, but not to coronary artery disease.

SLC17A2 SLC2A9 SLC17A1

3.22e-0511205319890391
Pubmed

Boldine suppresses dextran sulfate sodium-induced mouse experimental colitis: NF-κB and IL-6/STAT3 as potential targets.

STAT3 RELA

3.46e-052205226891685
Pubmed

Motor dysfunction and altered synaptic transmission at the parallel fiber-Purkinje cell synapse in mice lacking potassium channels Kv3.1 and Kv3.3.

KCNC1 KCNC3

3.46e-052205212930807
Pubmed

Role of crosstalk between STAT3 and mTOR signaling in driving sensitivity to chemotherapy in osteosarcoma cell lines.

STAT3 MTOR

3.46e-052205233448097
Pubmed

Excessive STAU1 condensate drives mTOR translation and autophagy dysfunction in neurodegeneration.

STAU1 MTOR

3.46e-052205238913026
Pubmed

Kv3.3 subunits control presynaptic action potential waveform and neurotransmitter release at a central excitatory synapse.

KCNC1 KCNC3

3.46e-052205235510987
Pubmed

Attenuation of EPO-dependent erythroblast formation by death-associated protein kinase-2.

DAPK2 DAPK1

3.46e-052205218535204
Pubmed

Phosphoproteomic analysis reveals hyperactivation of mTOR/STAT3 and LCK/Calcineurin axes in pediatric early T-cell precursor ALL.

STAT3 MTOR

3.46e-052205228082737
Pubmed

Glycyrrhizic acid inhibits leukemia cell growth and migration via blocking AKT/mTOR/STAT3 signaling.

STAT3 MTOR

3.46e-052205226191214
Pubmed

Lack of angiotensin II conversion to angiotensin III increases water but not alcohol consumption in aminopeptidase A-deficient mice.

AGT ENPEP

3.46e-052205216889841
Pubmed

Subcellular localization of the voltage-gated potassium channels Kv3.1b and Kv3.3 in the cerebellar dentate nucleus of glutamic acid decarboxylase 67-green fluorescent protein transgenic mice.

KCNC1 KCNC3

3.46e-052205218682278
Pubmed

Roles of STAT3 in protein secretion pathways during the acute-phase response.

STAT3 RELA

3.46e-052205223460517
Pubmed

Pegylated IFN-α suppresses hepatitis C virus by promoting the DAPK-mTOR pathway.

DAPK1 MTOR

3.46e-052205227930338
Pubmed

Nuclear translocation of STAT3 and NF-κB are independent of each other but NF-κB supports expression and activation of STAT3.

STAT3 RELA

3.46e-052205228089769
Pubmed

HUPO BPP pilot study: a proteomics analysis of the mouse brain of different developmental stages.

ENO1 ENO2

3.46e-052205217922513
Pubmed

NF-κB inducing kinase is a therapeutic target for systemic lupus erythematosus.

MAP3K14 RELA

3.46e-052205229330524
Pubmed

Importance of the alternative NF-κB activation pathway in inflammation-associated gastrointestinal carcinogenesis.

NFKB2 RELA

3.46e-052205227102559
Pubmed

Effects of the curly tail genotype on neuroepithelial integrity and cell proliferation during late stages of primary neurulation.

HSPG2 GRHL3

3.46e-052205211787818
Pubmed

Effects of mTOR-STAT3 on the migration and invasion abilities of hepatoma cell and mTOR-STAT3 expression in liver cancer.

STAT3 MTOR

3.46e-052205225063062
Pubmed

SF3B3-regulated mTOR alternative splicing promotes colorectal cancer progression and metastasis.

SF3B3 MTOR

3.46e-052205238671459
Pubmed

Unconventional p65/p52 NF-κB module regulates key tumor microenvironment-related genes in breast tumor-associated macrophages (TAMs).

NFKB2 RELA

3.46e-052205239278618
Pubmed

Ablation of Kv3.1 and Kv3.3 potassium channels disrupts thalamocortical oscillations in vitro and in vivo.

KCNC1 KCNC3

3.46e-052205218495891
Pubmed

TRIB3 Interacts with STAT3 to Promote Cancer Angiogenesis.

STAT3 TRIB3

3.46e-052205236245025
Pubmed

NF-κB RelA Is Required for Hepatoprotection during Pneumonia and Sepsis.

STAT3 RELA

3.46e-052205231160364
Pubmed

Complete structure of the human gene encoding neuron-specific enolase.

ENO1 ENO2

3.46e-05220522045099
Pubmed

Persistent Activation of NF-κB in BRCA1-Deficient Mammary Progenitors Drives Aberrant Proliferation and Accumulation of DNA Damage.

BRCA1 NFKB2

3.46e-052205227292187
Pubmed

ANG II activates effectors of mTOR via PI3-K signaling in human coronary smooth muscle cells.

AGT MTOR

3.46e-052205215317677
Pubmed

Isolation of murine neuron-specific and non-neuronal enolase cDNA clones.

ENO1 ENO2

3.46e-05220523801001
Pubmed

Spinocerebellar ataxia-13 Kv3.3 potassium channels: arginine-to-histidine mutations affect both functional and protein expression on the cell surface.

KCNC1 KCNC3

3.46e-052205223734863
Pubmed

HIPK2 directs cell type-specific regulation of STAT3 transcriptional activity in Th17 cell differentiation.

STAT3 HIPK2

3.46e-052205235344430
Pubmed

Biochemical characterization of the mouse muscle-specific enolase: developmental changes in electrophoretic variants and selective binding to other proteins.

ENO1 ENO3

3.46e-05220529169614
Pubmed

Stage-dependent therapeutic efficacy in PI3K/mTOR-driven squamous cell carcinoma of the skin.

MTOR GRHL3

3.46e-052205229238073
Pubmed

Purkinje-cell-restricted restoration of Kv3.3 function restores complex spikes and rescues motor coordination in Kcnc3 mutants.

KCNC1 KCNC3

3.46e-052205218448641
Pubmed

Integrin beta3 Leu33Pro polymorphism increases BRCA1-associated ovarian cancer risk.

ITGB3 BRCA1

3.46e-052205217220212
Pubmed

Allele-dependent changes of olivocerebellar circuit properties in the absence of the voltage-gated potassium channels Kv3.1 and Kv3.3.

KCNC1 KCNC3

3.46e-052205215217387
Pubmed

Expanding the Interactome of the Noncanonical NF-κB Signaling Pathway.

NFKB2 MAP3K14

3.46e-052205227416764
Pubmed

NF-κB inducing kinase, a central signaling component of the non-canonical pathway of NF-κB, contributes to ovarian cancer progression.

NFKB2 MAP3K14

3.46e-052205224533079
Pubmed

Within the hemopoietic system, LAR phosphatase is a T cell lineage-specific adhesion receptor-like protein whose phosphatase activity appears dispensable for T cell development, repertoire selection and function.

PTPRF PAX5

3.46e-052205211241288
Pubmed

Alcohol hypersensitivity, increased locomotion, and spontaneous myoclonus in mice lacking the potassium channels Kv3.1 and Kv3.3.

KCNC1 KCNC3

3.46e-052205211517255
Pubmed

Identification of a novel class of elastase isozyme, human pancreatic elastase III, by cDNA and genomic gene cloning.

CELA3B CELA3A

3.46e-05220522826474
Pubmed

Hepatocyte-specific mutation of both NF-κB RelA and STAT3 abrogates the acute phase response in mice.

STAT3 RELA

3.46e-052205222466650
Pubmed

Tetrandrine suppresses β‑glucan‑induced macrophage activation via inhibiting NF‑κB, ERK and STAT3 signaling pathways.

STAT3 RELA

3.46e-052205227121946
Pubmed

Presynaptic Kv3 channels are required for fast and slow endocytosis of synaptic vesicles.

KCNC1 KCNC3

3.46e-052205233508244
Pubmed

Ser289 phosphorylation activates both DAPK1 and DAPK2 but in response to different intracellular signaling pathways.

DAPK2 DAPK1

3.46e-052205231116076
Pubmed

Distribution of serum neuron-specific enolase and the establishment of a population reference interval in healthy adults.

ENO1 ENO2

3.46e-052205230779465
Pubmed

Sodium butyrate-induced DAPK-mediated apoptosis in human gastric cancer cells.

DAPK2 DAPK1

3.46e-052205222160140
Pubmed

Kv3 potassium channels control the duration of different arousal states by distinct stochastic and clock-like mechanisms.

KCNC1 KCNC3

3.46e-052205216553620
Pubmed

Receptor-mediated induction of aminopeptidase A (APA) of human glomerular epithelial cells (HGEC) by glucocorticoids.

AGT ENPEP

3.46e-05220521756856
Pubmed

Genetic Analysis of Human Chymotrypsin-Like Elastases 3A and 3B (CELA3A and CELA3B) to Assess the Role of Complex Formation between Proelastases and Procarboxypeptidases in Chronic Pancreatitis.

CELA3B CELA3A

3.46e-052205227999401
Pubmed

Serum CA125 and NSE: biomarkers of disease severity in patients with silicosis.

MUC16 ENO2

3.46e-052205224642341
Pubmed

Differential expression of muscle-specific enolase in embryonic and fetal myogenic cells during mouse development.

ENO1 ENO3

3.46e-05220522090519
Pubmed

NIK promotes tissue destruction independently of the alternative NF-κB pathway through TNFR1/RIP1-induced apoptosis.

NFKB2 MAP3K14

3.46e-052205226045047
Pubmed

mTOR mediates human trophoblast invasion through regulation of matrix-remodeling enzymes and is associated with serine phosphorylation of STAT3.

STAT3 MTOR

3.46e-052205219331815
Pubmed

Behavioral motor dysfunction in Kv3-type potassium channel-deficient mice.

KCNC1 KCNC3

3.46e-052205216923152
Pubmed

Accumulation of p100, a precursor of NF-κB2, enhances osteoblastic differentiation in vitro and bone formation in vivo in aly/aly mice.

NFKB2 MAP3K14

3.46e-052205222282470
Pubmed

The prognostic values of CA125, CA19.9, NSE, AND SCC for stage I NSCLC are limited.

MUC16 ENO2

3.46e-052205222674301
Pubmed

Tribbles homolog 3 attenuates mammalian target of rapamycin complex-2 signaling and inflammation in the diabetic kidney.

TRIB3 MTOR

3.46e-052205224676635
Pubmed

HIPK2 mediates M1 polarization of microglial cells via STAT3: A new mechanism of depression-related neuroinflammation.

STAT3 HIPK2

3.46e-052205236924038
Pubmed

[Association of single nucleotide polymorphisms of CSPG2 and HSPG2 genes with intracranial aneurysm in ethnic Han Chinese population].

HSPG2 VCAN

3.46e-052205223568740
Pubmed

Pals-associated tight junction protein functionally links dopamine and angiotensin II to the regulation of sodium transport in renal epithelial cells.

AGT PATJ

3.46e-052205219563532
Pubmed

Molecular cloning of complementary DNA encoding one of the human pancreatic protease E isozymes.

CELA3B CELA3A

3.46e-05220522460440
Pubmed

Nucleotide sequences of cDNAs alpha and gamma enolase mRNAs from mouse brain.

ENO1 ENO2

3.46e-05220522362815
Pubmed

Peptidylarginine deiminase modulates the physiological roles of enolase via citrullination: links between altered multifunction of enolase and neurodegenerative diseases.

ENO1 ENO2

3.46e-052205222551201
Pubmed

[STAT3 and NF-κB is activated in papillary thyroid carcinoma tissues].

STAT3 RELA

3.46e-052205227667468
Pubmed

Increased motor drive and sleep loss in mice lacking Kv3-type potassium channels.

KCNC1 KCNC3

3.46e-052205215005717
Pubmed

An epithelial Nfkb2 pathway exacerbates intestinal inflammation by supplementing latent RelA dimers to the canonical NF-κB module.

NFKB2 RELA

3.46e-052205234155144
Pubmed

Physical and functional interactions between STAT3 and ZIP kinase.

DAPK3 STAT3

3.46e-052205216219639
Pubmed

Mammalian target of rapamycin inhibitors, temsirolimus and torin 1, attenuate stemness-associated properties and expression of mesenchymal markers promoted by phorbol-myristate-acetate and oncostatin-M in glioblastoma cells.

STAT3 MTOR

3.46e-052205228351321
Pubmed

Mammalian hemicentin 1 is assembled into tracks in the extracellular matrix of multiple tissues.

HMCN2 HMCN1

3.46e-052205232035013
Pubmed

Epigenetic induction of lipocalin 2 expression drives acquired resistance to 5-fluorouracil in colorectal cancer through integrin β3/SRC pathway.

ITGB3 LCN2

3.46e-052205234588619
Pubmed

A hepatocyte-specific transcriptional program driven by Rela and Stat3 exacerbates experimental colitis in mice by modulating bile synthesis.

STAT3 RELA

3.46e-052205239137024
Pubmed

Rescue of motor coordination by Purkinje cell-targeted restoration of Kv3.3 channels in Kcnc3-null mice requires Kcnc1.

KCNC1 KCNC3

3.46e-052205220016089
Pubmed

Schisandrin A reverses doxorubicin-resistant human breast cancer cell line by the inhibition of P65 and Stat3 phosphorylation.

STAT3 RELA

3.46e-052205229181822
Pubmed

Collagen XVII Shedding Suppresses Re-Epithelialization by Directing Keratinocyte Migration and Dampening mTOR Signaling.

COL17A1 MTOR

3.46e-052205226827763
InteractionTOP3B interactions

MYCBP2 PSENEN PFAS MBD6 ARHGEF11 ADCY9 STAU1 HEG1 PTPRF PTPRS NFKB2 MLLT6 HERC2 MCF2L PLXNA1 ABCC10 HSPG2 FRAS1 DOCK9 AOC2 HECTD4 MYOM3 ADGRA2 ATP13A2 KCNH3 HIVEP3 ARAP3 TRIB3 MTOR FURIN MARK4 WDFY3 IL4R DDX28 RAB11FIP3

1.26e-06147020135int:TOP3B
GeneFamilyAnkyrin repeat domain containing|Death associated protein kinases

DAPK2 DAPK1 DAPK3

4.69e-06514231021
GeneFamilyFibronectin type III domain containing

IGFN1 FNDC1 FNDC7 PTPRF PTPRS USH2A COL12A1 COL20A1 MYOM3

4.86e-061601429555
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

IGFN1 HMCN2 PTPRF PTPRS HSPG2 MYOM3 HMCN1

2.83e-041611427593
GeneFamilySolute carriers

SLC17A2 SLC41A3 SLC22A20P SLC25A42 SLC2A9 SLC13A3 FLVCR2 SLC17A5 SLC17A1 SLC18A2 SLC25A1

2.91e-0439514211752
GeneFamilyCadherin related

DCHS2 FAT2 DCHS1

2.98e-0417142324
GeneFamilyAnkyrin repeat domain containing|NF-kappa B complex subunits

NFKB2 RELA

6.03e-04514221254
GeneFamilyAdhesion G protein-coupled receptors, subfamily G

ADGRG4 ADGRG2

1.25e-0371422917
GeneFamilyFibulins

HMCN2 HMCN1

1.66e-0381422556
GeneFamilyG protein-coupled receptors, Class F frizzled

FZD9 SMO

3.22e-03111422286
GeneFamilyPotassium voltage-gated channels

KCNC1 KCNC3 KCNH3

3.79e-03401423274
GeneFamilyImmunoglobulin like domain containing

CADM4 TMEM81 HMCN2 HSPG2 MYOM3 ADGRA2

4.22e-031931426594
CoexpressionNABA_CORE_MATRISOME

IMPG1 FNDC1 FNDC7 HMCN2 USH2A VWA3A HSPG2 FRAS1 COL12A1 COL17A1 COL20A1 TGFBI HMCN1 VCAN

3.52e-0827520314M5884
CoexpressionNABA_CORE_MATRISOME

IMPG1 FNDC1 FNDC7 HMCN2 VWA3A HSPG2 FRAS1 COL12A1 COL17A1 COL20A1 TGFBI HMCN1 VCAN

2.09e-0727020313MM17057
CoexpressionLAKE_ADULT_KIDNEY_C3_PROXIMAL_TUBULE_EPITHELIAL_CELLS_S1_S2

TRPS1 VPS13A FRAS1 SLC2A9 SLC13A3 CUBN SLC17A1 WDFY3 PATJ ENPEP RAB11FIP3

1.33e-0622120311M39222
CoexpressionKOINUMA_TARGETS_OF_SMAD2_OR_SMAD3

CTNNAL1 MARK3 BNC1 FAT2 PTPRF WDR89 COL12A1 COL17A1 RTN4 MAP3K14 NIBAN2 RGS12 EEF2KMT TGFBI AIFM1 FURIN WDFY3 GRHL3 ENO1 IL4R

9.79e-0684320320M2356
CoexpressionGSE37532_VISCERAL_ADIPOSE_TISSUE_VS_LN_DERIVED_PPARG_KO_TREG_CD4_TCELL_DN

PFAS MBD6 DLGAP3 MTA3 SLC25A42 MUC16 NSUN3 FURIN

1.33e-051392038M8948
CoexpressionLINDVALL_IMMORTALIZED_BY_TERT_DN

BLM FNDC1 HSPG2 ARHGAP5 VCAN ENO2

2.22e-05732036M1561
CoexpressionMILI_PSEUDOPODIA_HAPTOTAXIS_DN

ENDOD1 SPNS1 HEG1 PTPRF PTPRS NFKB2 NFKBIE ABHD1 PLXNA1 WDR62 HSPG2 RTN4 PIGU ADGRA2 SF3B3 MIGA2 IL4R

2.48e-0568120317M5314
CoexpressionGSE360_L_DONOVANI_VS_M_TUBERCULOSIS_MAC_DN

STAU1 HEG1 NFKB2 SCN9A ABCC10 RELA ARHGAP5 SLC18A2 MUC6

2.66e-051992039M5242
CoexpressionGSE22103_UNSTIM_VS_LPS_STIM_NEUTROPHIL_UP

HIVEP1 MLLT6 EXOSC3 RELA NIBAN2 NUP35 HIVEP3 MARK4 IL4R

2.76e-052002039M7794
CoexpressionMILI_PSEUDOPODIA_HAPTOTAXIS_DN

ENDOD1 SPNS1 HEG1 PTPRF PTPRS NFKB2 NFKBIE ABHD1 PLXNA1 WDR62 HSPG2 RTN4 PIGU ADGRA2 SF3B3 MIGA2 IL4R

3.68e-0570320317MM1055
CoexpressionNABA_MATRISOME

IMPG1 FNDC1 FNDC7 HMCN2 AGT USH2A PLXNA1 VWA3A HSPG2 FRAS1 COL12A1 COL17A1 COL20A1 MUC16 TGFBI CELA3B CELA3A HMCN1 VCAN ADAMTS14 MUC6

5.14e-05102620321M5889
CoexpressionRASHI_RESPONSE_TO_IONIZING_RADIATION_2

HIVEP1 STAT3 NFKB2 HIPK2 RELA LCN2 TRIB3

5.56e-051252037M5888
CoexpressionGSE6269_HEALTHY_VS_STAPH_PNEUMO_INF_PBMC_DN

MAP1A ARHGEF11 COL17A1 FLVCR2 LCN2 FURIN VCAN WDFY3

5.66e-051702038M5649
CoexpressionRASHI_RESPONSE_TO_IONIZING_RADIATION_2

HIVEP1 STAT3 NFKB2 HIPK2 RELA LCN2 TRIB3

6.14e-051272037MM1113
ToppCellBAL-Mild-cDC_0|Mild / Compartment, Disease Groups and Clusters

ABL2 ADCY9 DLGAP3 PTPRF TOMM40L SNX32 CD300LF PIGU FURIN VCAN

4.65e-09163205107047d3ba847930f42a6d5f71e18d49f3071c6409
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DAPK2 DAPK1 PTPRF FHIP1A HSPG2 FRAS1 FLVCR2 DENND3 PATJ CACNA2D3

1.27e-0818120510b45b11428d13950369347e051d4d517efb2bd4fd
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DAPK1 RIPOR3 MCF2L FRAS1 SUSD4 COL12A1 HIPK2 RGS12 PATJ CACNA2D3

1.34e-0818220510eb138aa1dca9373f1586600f258df06dcf56d81f
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DAPK2 DAPK1 PTPRF FHIP1A HSPG2 FRAS1 FLVCR2 DENND3 PATJ CACNA2D3

1.65e-08186205103aebe163799109ffc67e4e10ee47c2dd0886a92c
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC17A2 AADACL2 USH2A VWA3A FRAS1 COL12A1 PKHD1L1 HMCN1 CACNA2D3

5.90e-081602059c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC17A2 AADACL2 USH2A VWA3A FRAS1 COL12A1 PKHD1L1 HMCN1 CACNA2D3

5.90e-08160205925c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellControl-Epithelial_alveolar-AT_1-Differentiating_AT1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DAPK2 DAPK1 FHIP1A HSPG2 FRAS1 FLVCR2 DENND3 PATJ CACNA2D3

1.40e-0717720599af14a056eb6d88c6f11b09f6d4c0d3448d647d5
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DAPK2 DAPK1 PTPRF FHIP1A HSPG2 FRAS1 NIBAN2 PATJ CACNA2D3

1.95e-07184205942ce855b4f8475a8298192feec785bdc69bc5bb0
ToppCell343B-Epithelial_cells-Epithelial-I_(AT1)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DAPK2 FNDC1 HEG1 PLXNA1 HSPG2 COL12A1 TRGV9 DENND3 ADGRG2

1.95e-071842059c7073d1b2c4fdb154d87678b92a0629c02116972
ToppCell343B-Epithelial_cells-Epithelial-I_(AT1)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DAPK2 FNDC1 HEG1 PLXNA1 HSPG2 COL12A1 TRGV9 DENND3 ADGRG2

1.95e-0718420591ed558a88215b248431c524ea16f13d9022ae98c
ToppCellfacs-Brain_Non-Myeloid-Cerebellum|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PHYHIP FAT2 FNDC7 KCNC1 KCNC3 SYT13 LCN2 PATJ ENO2

2.04e-071852059c083a4974590b9ed3ecafedd3e9cdebc5047fe39
ToppCellfacs-Trachea-18m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l54|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CTNNAL1 RIPOR3 TMEM81 TC2N SUSD4 DOCK9 LCN2 PKHD1L1 ARAP3

2.04e-07185205959acaf025353405948dc34ccccf37ec5c08ea903
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADCY9 MCF2L SLC25A42 SLC2A9 SLC13A3 CUBN SLC17A1 ENPEP RAB11FIP3

2.14e-0718620595784d255e9ca449d375d81938d0fbbd8a7eb44f6
ToppCellCOVID-19-kidney-Mito-rich_PCT|kidney / Disease (COVID-19 only), tissue and cell type

AGT SLC2A9 MYOM3 SLC13A3 CUBN SLC17A1 PATJ ENPEP RAB11FIP3

2.24e-071872059738ec2611b4be6a08eedad16b57fba84e1f11fef
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC25A42 SLC2A9 MYOM3 SLC13A3 CUBN SLC17A1 PATJ ENPEP RAB11FIP3

2.34e-071882059f3edcefeef2ce19086032d98b243c02a6d542b38
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC25A42 SLC2A9 MYOM3 SLC13A3 CUBN SLC17A1 PATJ ENPEP RAB11FIP3

2.34e-0718820590792432cd4c564dea1102241ea9884f7ced7658c
ToppCellfacs-Aorta-Heart-3m-Mesenchymal-fibroblast|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BNC1 FNDC1 HEG1 PTPRF PTPRS FRAS1 ADGRA2 VCAN SMO

2.67e-0719120599214655dca96d766737c9f30b624d7fe7050342e
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

DCHS2 HTR3C BNC1 ACSBG2 USH2A FRAS1 CELA3B BPIFB4 MUC6

2.92e-071932059315840bc48899f3a36d57b19197509de19716e3d
ToppCellRV-10._Endothelium_II|RV / Chamber and Cluster_Paper

DAPK1 HEG1 HSPG2 DOCK9 HIPK2 PKHD1L1 ARAP3 HMCN1 IL4R

2.92e-07193205901c2df9206f1527c578e808978e58196c35e72f5
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FHIP1A FRAS1 SLC13A3 CUBN SLC17A1 PATJ ENPEP CACNA2D3 RAB11FIP3

2.92e-07193205982e8a4c40299ffcdfd5a0da711bb9de6fb8a2eaa
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FHIP1A FRAS1 SLC2A9 SLC13A3 CUBN SLC17A1 PATJ ENPEP RAB11FIP3

3.05e-0719420597002937e8903e037332a215d00fbc7c7843b33f2
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

DAPK2 DAPK1 PTPRF PLXNA1 FRAS1 FLVCR2 DENND3 PATJ CACNA2D3

3.78e-071992059d43c605a4ff221cf78d91678c15d2ad20f831c7f
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

DAPK2 DAPK1 PTPRF PLXNA1 FRAS1 FLVCR2 DENND3 PATJ CACNA2D3

3.94e-072002059ddfb1f006365bf16203ee49f20200f68220cc288
ToppCellLPS_IL1RA|World / Treatment groups by lineage, cell group, cell type

ITGB3 STAT3 HEG1 NFKB2 NFKBIE COL12A1 DOCK9 ENO1 IL4R

3.94e-072002059a02fa5b3c4723a6eaa3c685588666c710478dd25
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c4-CD14-CD16|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

RUSC2 TOMM40L AADACL2 ADGRA2 SLC17A5 CELA3B ARAP3 WDFY3

4.42e-071482058fd0d8386b94adb1bdc993fbb44d2d87852bfd7f0
ToppCellPND07-28-samps-Mesenchymal-Mesothelial|PND07-28-samps / Age Group, Lineage, Cell class and subclass

PHYHIP ADCY9 BNC1 FHIP1A FRAS1 EPB41L4B MUC16 PKHD1L1

6.60e-071562058574f761962a7dd3308bd41fc529dd3ea1b8625f8
ToppCellPND07-28-samps-Mesenchymal-Mesothelial-Mesothelial|PND07-28-samps / Age Group, Lineage, Cell class and subclass

PHYHIP ADCY9 BNC1 FHIP1A FRAS1 EPB41L4B MUC16 PKHD1L1

6.60e-071562058605d95a900e1443d3f6aae163ef2e893d3293203
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_0|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ABL2 TRPS1 ADCY9 DLGAP3 SNX32 NFKB2 VCAN CACNA2D3

7.62e-071592058ded4e3626a62fb6334403b7213b467fb7e8131c3
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_0|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ABL2 TRPS1 ADCY9 DLGAP3 SNX32 NFKB2 VCAN CACNA2D3

7.62e-0715920582f6c60ddff2208a68146f9786143d9aefd528840
ToppCellEntopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Pdgfa_(Mural.Rgs5Acta2.Pdgfa)-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

FNDC7 FHIP1A CD300LF PCDHGA7 AOC2 LIPT1 ADAMTS14

1.00e-0611420572cc5d2da5573650c5232a01e2d2128082c4bffcb
ToppCellEntopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Pdgfa_(Mural.Rgs5Acta2.Pdgfa)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

FNDC7 FHIP1A CD300LF PCDHGA7 AOC2 LIPT1 ADAMTS14

1.00e-061142057fceb7cc590a47380145fc0d854c9f2350dbb0a59
ToppCellwk_15-18-Epithelial-Airway_epithelial_progenitor-epi-prox-progenitor_intermediate_|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

DAPK2 DAPK1 PTPRF ZNF608 FHIP1A FRAS1 SUSD4 MUC6

1.01e-061652058f6887c64af0f26e33316bc5587487e24d76ece2a
ToppCellB_cells-pDCs|World / Immune cells in Kidney/Urine in Lupus Nephritis

MAP1A CADM4 PTPRS SCN9A FHIP1A HSPG2 TGFBI DNAH12

1.15e-061682058dc8f94424f60ab56facdcffa969e7f3466ee1b6e
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC25A42 SLC2A9 MYOM3 SLC13A3 CUBN SLC17A1 ENPEP RAB11FIP3

1.32e-061712058f5014e3c387fe3118944af392abe10d6b9b0abab
ToppCellfacs-Marrow-B-cells-24m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WDR89 USH2A SYT13 FRAS1 COL12A1 HMCN1 PAX5 CACNA2D3

1.57e-061752058887e75fc90e59a6394d62f3c048a9cfdf6707725
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DAPK2 PTPRF FHIP1A FRAS1 EPB41L4B DENND3 PATJ CACNA2D3

1.86e-06179205804ce3673e46606f63d9c87bcba3a64c96817d812
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MCF2L SLC25A42 SLC2A9 SLC13A3 CUBN SLC17A1 ENPEP RAB11FIP3

1.94e-061802058f8bdfd7bf7b3d52c659a29d8f5f80858e79da83e
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SCN9A SLC25A42 SLC2A9 SLC13A3 CUBN SLC17A1 ENPEP RAB11FIP3

1.94e-0618020581363b3254470f6ff98630d1df83a1bdbacc137e0
ToppCell3'_v3-blood-Myeloid_Dendritic-pDC|blood / Manually curated celltypes from each tissue

HIVEP1 MAP1A CADM4 DAPK1 PTPRS SCN9A RAB40B FHIP1A

2.02e-06181205866d890a105f955dca91d6e5e6c730d1a68ee9233
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DAPK1 RIPOR3 FRAS1 COL12A1 HIPK2 RGS12 PATJ CACNA2D3

2.02e-0618120589d782ba5cf5a172cb4f447763fc50e5b13ef7dd9
ToppCellCOVID-19-kidney-PCT-S1|COVID-19 / Disease (COVID-19 only), tissue and cell type

FRAS1 SLC2A9 SLC13A3 CUBN SLC17A1 PATJ ENPEP RAB11FIP3

2.19e-0618320586878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MCF2L SLC25A42 SLC2A9 SLC13A3 CUBN SLC17A1 ENPEP RAB11FIP3

2.19e-06183205884b64cf728629c3af9a8d2ed15b93adf562c54b8
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MCF2L SLC25A42 SLC2A9 SLC13A3 CUBN SLC17A1 ENPEP RAB11FIP3

2.19e-061832058facd6dbe0851b537d70a899ac7485714ab27d071
ToppCellCOVID-19-kidney-PCT-S1|kidney / Disease (COVID-19 only), tissue and cell type

VPS13A SLC2A9 MYOM3 SLC13A3 CUBN SLC17A1 ENPEP RAB11FIP3

2.28e-06184205851ed1ebfdef45149541917c66cbacad87072e51f
ToppCellPND07-28-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_C|PND07-28-samps / Age Group, Lineage, Cell class and subclass

DES FNDC1 AGT COL12A1 TGFBI HMCN1 ADGRG2 CACNA2D3

2.37e-061852058427176ad9ab8d9511200fb0a132cfd1e835fe35c
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DAPK2 DAPK1 TC2N PTPRF FHIP1A FRAS1 PATJ CACNA2D3

2.47e-0618620584e94158db52df41d71e67b02b9895a358eebee0f
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADCY9 MCF2L SLC25A42 SLC2A9 SLC13A3 CUBN SLC17A1 RAB11FIP3

2.57e-0618720583ae3b8de1a195d4d5057cf3c64fcdb5f48681ce5
ToppCellCOVID-19-kidney-tDL|kidney / Disease (COVID-19 only), tissue and cell type

ADCY9 VPS13A SLC2A9 SLC13A3 CUBN SLC17A1 ENPEP RAB11FIP3

2.57e-061872058d35d27ca3c0e65f92f4508e1cb98a743f44fdcdf
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DAPK2 DAPK1 PTPRF FHIP1A FRAS1 NIBAN2 PATJ CACNA2D3

2.57e-06187205858d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MCF2L SLC25A42 SLC2A9 SLC13A3 CUBN SLC17A1 ENPEP RAB11FIP3

2.57e-061872058dcf6475ece5b34d9d58a0d1f51c18acedb19c119
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MCF2L SLC25A42 SLC2A9 SLC13A3 CUBN SLC17A1 ENPEP RAB11FIP3

2.57e-061872058f1356273bd3587b6883295edf15cb9cdb706c057
ToppCellRA-10._Endothelium_II|World / Chamber and Cluster_Paper

DAPK1 HSPG2 DOCK9 HIPK2 PKHD1L1 HMCN1 VCAN IL4R

2.78e-06189205875c248b9de5e2fb7a0baa8cdbab516e575cc4394
ToppCellCOVID-19-kidney-PCT-S2|kidney / Disease (COVID-19 only), tissue and cell type

SLC2A9 MYOM3 SLC13A3 CUBN SLC17A1 PATJ ENPEP RAB11FIP3

2.78e-0618920580be5c669b6b308bd98ddb70c84877c62a6244bbd
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF608 SLC2A9 MYOM3 FLVCR2 CUBN SLC17A1 ENPEP RAB11FIP3

2.89e-061902058989d4eefd22d66ecb857836f8fdbcf41e3047f84
ToppCellfacs-Lung-nan-3m-Mesenchymal-pulmonary_interstitial_fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DES AGT SLC25A42 COL12A1 PNMT TGFBI ADGRG2 CACNA2D3

2.89e-061902058c7bd087f36321cec61b98657433b4d19d135791f
ToppCellfacs-Lung-nan-3m-Mesenchymal-Myofibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DES AGT SLC25A42 COL12A1 PNMT TGFBI ADGRG2 CACNA2D3

2.89e-061902058834218fcc59df5e7e52de154272f3d55d81d0dac
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MCF2L SLC2A9 SLC13A3 CUBN SLC17A1 PATJ ENPEP RAB11FIP3

3.01e-0619120581c1d13144259b998d4a0e85142f7afef2ef1e63f
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MCF2L SLC2A9 SLC13A3 CUBN SLC17A1 PATJ ENPEP RAB11FIP3

3.01e-0619120583c464645d0e7e423f791bd63bf5bcf11f6b590d3
ToppCellHealthy-pDC|World / disease group, cell group and cell class

MAP1A CADM4 DAPK2 PTPRS SCN9A FHIP1A ATP13A2 TGFBI

3.01e-0619120586e1d825dc33b915b95f13ccd237a552160a4be98
ToppCellrenal_cortex_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 SLC2A9 SLC13A3 CUBN SLC17A1 SSH2 PATJ RAB11FIP3

3.13e-061922058e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCellHealthy-pDC|Healthy / disease group, cell group and cell class

MAP1A CADM4 DAPK2 PTPRS SCN9A FHIP1A ATP13A2 TGFBI

3.13e-06192205833d695a28d22b4af111df9591830a33bb7ef7b2d
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TRPS1 APOBR SLC22A20P NIBAN2 SLA TGFBI FURIN VCAN

3.25e-061932058d9bb77214bb92e8392cf74e3bfdf177a96fd71ea
ToppCellRV-10._Endothelium_II|World / Chamber and Cluster_Paper

DAPK1 HSPG2 DOCK9 HIPK2 PKHD1L1 ARAP3 HMCN1 IL4R

3.25e-0619320582531266bc57339d4e2b22a88817008e32b8c1598
ToppCellLPS-antiTNF-Endothelial-Endothelial-Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CTNNAL1 HEG1 ZNF608 MCF2L SUSD4 DOCK9 ARAP3 HMCN1

3.25e-0619320586e1982d089a9de628e6006d23ff78a223fbd9f47
ToppCelldroplet-Bladder-nan-24m-Epithelial-bladder_mesenchymal_cell_(Car3+)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IRGM FNDC1 HSPG2 COL12A1 TGFBI VCAN ENPEP IL4R

3.25e-0619320582d891c00b8f0aace17d4c300b63e2341dcffa199
ToppCellLV-10._Endothelium_II|LV / Chamber and Cluster_Paper

HEG1 HSPG2 DOCK9 HIPK2 PKHD1L1 ARAP3 HMCN1 IL4R

3.38e-061942058b6cc849fa08599bff9839ef382d190cc964e273e
ToppCellfacs-Lung-3m-Mesenchymal-myofibroblast-myofibroblast_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DES AGT SLC25A42 COL12A1 PNMT TGFBI ADGRG2 CACNA2D3

3.51e-061952058c6bb16c0076639c6ddef1a15d8cba44bc29c077d
ToppCellfacs-Lung-3m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DES AGT SLC25A42 COL12A1 PNMT TGFBI ADGRG2 CACNA2D3

3.51e-061952058ea89f80d3d7e9f737442f7c1aa1791d277ffc90c
ToppCellPND01-03-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_B|PND01-03-samps / Age Group, Lineage, Cell class and subclass

FNDC1 AGT COL12A1 TGFBI ADGRG2 VCAN ADAMTS14

3.60e-0613820578d70e64843f7c3be8ee4203cc126fdf1001f0df5
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_hypoxia|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ABL2 APOBR NIBAN2 SLA TGFBI FURIN VCAN ENO1

3.64e-061962058a44a648bf209ce037bfc7b3adfcb220aab60728c
ToppCellPND10-Mesenchymal|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DES FNDC1 AGT TGFBI HMCN1 ADGRG2 VCAN ENPEP

3.64e-061962058ace167a40adb7022b365be3c2b1cbd4ba963739a
ToppCellIPF-Epithelial|IPF / Disease state, Lineage and Cell class

PTPRF AADACL2 FHIP1A VWA3A EPB41L4B DYNC2H1 DNAH12 PATJ

3.64e-06196205887d9881cfec461a5d89b688a83749b618c519485
ToppCellP03-Mesenchymal-myocytic_cell-aortic_smooth_muscle_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

DES FNDC1 AGT COL12A1 TGFBI HMCN1 ADGRG2 ADAMTS14

3.78e-0619720582cec938caf6ffd031cea37277071487e59b2c71c
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DES FNDC1 AGT COL12A1 TGFBI HMCN1 ADGRG2 ADAMTS14

3.78e-061972058090a251194da3e2806989d9a522588f83f52da7f
ToppCellControl_saline-Epithelial_alveolar-AT_1-Differentiating_AT1|Control_saline / Treatment groups by lineage, cell group, cell type

DAPK2 DAPK1 PTPRF PLXNA1 MICAL1 FRAS1 FLVCR2 DENND3

3.93e-06198205885f424cd9bb3117c9e322031024aabb87696ce47
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_only / Treatment groups by lineage, cell group, cell type

MYCBP2 STAT3 DES NFKB2 NFKBIE HIVEP3 VCAN IL4R

4.07e-061992058fde2b65afde69f402f1b7b056eaa266e9fd5b227
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

CTNNAL1 HEG1 ZNF608 MCF2L COL12A1 DOCK9 ARAP3 HMCN1

4.23e-062002058dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Neuronal-Intermediate|GW16 / Sample Type, Dataset, Time_group, and Cell type.

HIVEP1 ABL2 DAPK3 SYT13 SUSD4 ZNF540 KCTD3 ENPEP

4.23e-062002058a3fcd901cb281920f1bafdfd676399a6dc37355e
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Col15a1_(Col15a1)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

ABL2 RIPOR3 FNDC7 FHIP1A COL12A1 PAX5

7.78e-0610220560bbc6344d0baee47326a16a89773bb5c68a7b040
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Col15a1_(Col15a1)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

ABL2 RIPOR3 FNDC7 FHIP1A COL12A1 PAX5

7.78e-06102205611fbdb428824023603e9d4ee41e957ba84e7c29e
ToppCellHippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1|Hippocampus / BrainAtlas - Mouse McCarroll V32

ABL2 ACSS3 HSPG2 COL12A1 SLC13A3 FLVCR2 TGFBI

9.14e-06159205792049a8d8fc9997d8d0d76500c72596a9b2394e0
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

HERC2 MCF2L DOCK9 MYOM3 CUBN PIGU PATJ

9.92e-0616120575fba13f0aa5002f7eefe219e2c6a07e163f1a50d
ToppCellPND10-Endothelial-Endothelial_lymphatic|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CTNNAL1 DAPK2 FZD9 MROH7 SUSD4 PKHD1L1 RAB11FIP3

1.12e-051642057f13b8d9b7f42193f333d9a77571a1dde6bbb48d8
ToppCellPND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CTNNAL1 DAPK2 FZD9 MROH7 SUSD4 PKHD1L1 RAB11FIP3

1.12e-0516420574cfc9f92e49f86d3639e018b35b6a60dc62f494a
ToppCellPND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CTNNAL1 DAPK2 FZD9 MROH7 SUSD4 PKHD1L1 RAB11FIP3

1.12e-0516420577a8e5ef52a8fd2877d59ef0696af8a7af90bbed6
ToppCellPND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CTNNAL1 DAPK2 FZD9 MROH7 SUSD4 PKHD1L1 RAB11FIP3

1.12e-0516420575e5bd81414ea2d64f73cdef19a0a78c17bec8c18
ToppCellPCW_13-14-Hematologic_ErythroMegGranulo-Hem_ErythroMeg-im_megakaryocyte2_(17)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

RIPOR3 ITGB3 TC2N LCN2 SLA PKHD1L1 SLC18A2

1.16e-051652057d2ab667ff53f538b12ee4e07ea4b4d118600a228
ToppCelldroplet-Heart-nan-24m-Hematologic-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GMEB2 BLM BRCA1 ABCC10 SLC2A9 DENND3 MARK4

1.26e-051672057bad33497ceeab968a7eb8a48b921c6f936390743
ToppCell10x5'-lymph-node_spleen-Myeloid_Dendritic-pDC|lymph-node_spleen / Manually curated celltypes from each tissue

MAP1A CADM4 PTPRS SCN9A FHIP1A TGFBI CACNA2D3

1.31e-051682057cfed36fece51871a5abbcde71f6bd5e7212357ff
ToppCellPND28-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MAP1A DES AGT PNMT TGFBI ADGRG2 CACNA2D3

1.36e-05169205742a9b8c77d2a4d68b01e4db38f8a1af53c9c814f
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC8 VWA3A TDRD5 DYNC2H1 CUBN DNAH12 CFAP418

1.36e-0516920578bca402e144819cb9a8d431d6bf9429be2fff6d6
ToppCellPND28-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MAP1A DES AGT PNMT TGFBI ADGRG2 CACNA2D3

1.36e-05169205788aa2246ede582c2e11de63228d76f520889ecb3
ToppCellPND28-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MAP1A DES AGT PNMT TGFBI ADGRG2 CACNA2D3

1.36e-051692057a6a5b00912b653fad2ca7f096deaf35c9ef85e5b
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCN9A WDR89 USH2A FRAS1 CUBN LCN2 PKHD1L1

1.36e-05169205712bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BTNL8 HEG1 DOCK9 PKHD1L1 HIVEP3 ARAP3 IL4R

1.58e-051732057f193c63cc536d891c9d23043765e320252bb6e65
ToppCellCTRL-Lymphoid-pDC|Lymphoid / Disease state, Lineage and Cell class

MAP1A CADM4 PFAS PTPRS SCN9A FHIP1A TGFBI

1.64e-051742057ff4315e9fad198cc323fc987deb8652da137cf98
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DAPK2 PTPRF ABCC10 SUSD4 EPB41L4B AOC2 FLVCR2

1.70e-05175205796219e58dcb327fd27190be78193e7a0d611e62b
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DAPK2 PTPRF ABCC10 SUSD4 EPB41L4B AOC2 FLVCR2

1.70e-051752057cb974fbebe8cb58c7d3f7defabb4e056f2fee5fa
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTNNAL1 DAPK2 ITGB3 TC2N SUSD4 LCN2 PKHD1L1

1.70e-051752057f6e1d7297a4dbb38e1ab4f738d91f0e62abaee69
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WDR89 USH2A FRAS1 COL12A1 HMCN1 PAX5 CACNA2D3

1.77e-051762057c6484334187f64cd00cd35e77d8ae436556b4260
DrugAC1L18ZV

BLM AOC2 ENO1 ENO2 ENO3

4.24e-08122055CID000000329
DrugN-succinylphenylglycine

ENO1 ENO2 ENO3

7.19e-0732053CID000448582
DrugAC1MOUJL

ENO1 ENO2 ENO3

7.19e-0732053CID003400924
DrugC03356

ENO1 ENO2 ENO3

7.19e-0732053CID000439988
Drug3-bromo-2-(bromomethyl)propionic acid

ENO1 ENO2 ENO3

7.19e-0732053CID000318915
DrugC04309

ENO1 ENO2 ENO3

7.19e-0732053CID000440293
Drug2,3-diketo-1-phosphohexane

ENO1 ENO2 ENO3

7.19e-0732053CID000192519
DrugFillalbin [4540-25-4]; Down 200; 13.8uM; PC3; HT_HG-U133A

DAPK3 ADCY9 RUSC2 MCF2L WDR62 BRSK2 RGS12 TGFBI SLC18A2 MARK4 ENO3

1.66e-06195205114092_DN
Drugdimethyl chlorophosphate

ENO1 ENO2 ENO3

2.86e-0642053CID000101863
Drug[2-(oxidoamino)-2-oxoethyl]phosphonic acid

ENO1 ENO2 ENO3

2.86e-0642053CID011969443
Drug3-aminoenolpyruvate-2-phosphate

ENO1 ENO2 ENO3

2.86e-0642053CID003037152
Drug2-ptz

ENO1 ENO2 ENO3

2.86e-0642053CID000445375
Drugtricyclohexylammonium

ENO1 ENO2 ENO3

2.86e-0642053CID000226271
Drugsaracatinib

SRMS STAT3 AGT MTOR AIFM1

3.87e-06272055CID010302451
Drugtetrahydroaldosterone-3-glucuronide

STAT3 DES ENO1 ENO2 ENO3

5.61e-06292055CID000167918
DrugN-methylacrylamide

ENO1 ENO2 ENO3

7.10e-0652053CID000014471
DrugAC1L1CAI

ENO1 ENO2 ENO3

7.10e-0652053CID000000145
Drugtartronate semialdehyde phosphate

ENO1 ENO2 ENO3

7.10e-0652053CID000151938
Drug2-phospho-3-butenoic acid

ENO1 ENO2 ENO3

7.10e-0652053CID000191423
Drug1-Pdmsp

ENO1 ENO2 ENO3

7.10e-0652053CID000000561
DrugBMS-345541

STAT3 NFKB2 MAP3K14 RELA AIFM1

9.31e-06322055CID009813758
DrugNiclosamide

CYP1A2 UNC93A ITGB3 STAT3 FZD9 RELA MTOR AIFM1 ENO2 ENO3

9.59e-0619120510ctd:D009534
DrugFreon 22

ITGB3 ENO1 ENO2 ENO3

1.07e-05162054CID000006372
DrugCyclobenzaprine hydrochloride [6202-23-9]; Up 200; 12.8uM; PC3; HT_HG-U133A

DAPK3 HEG1 HTR1D SLC2A9 RGS12 DENND3 SLC17A5 TRIB3 MARK4 PAX5

1.20e-05196205104252_UP
Drugdimidium

ENO1 ENO2 ENO3

1.41e-0562053CID000068207
DrugZ(2-Cl)-OSu

ENO1 ENO2 ENO3

1.41e-0562053CID000580665
Drug4-(N,N-dimethylamino)cinnamoyl-CoA

ENO1 ENO2 ENO3

1.41e-0562053CID000445461
DrugAC1L1A7Z

AOC2 ENO1 ENO2 ENO3

1.77e-05182054CID000000874
Drugpurpurin-18

EXOSC3 ENO1 ENO2 ENO3

2.23e-05192054CID005489047
Drugiomeprol

STAT3 RELA LCN2

2.45e-0572053ctd:C057937
DrugN-tert-butylacrylamide

ENO1 ENO2 ENO3

2.45e-0572053CID000007877
Drugglycidol phosphate

ENO1 ENO2 ENO3

2.45e-0572053CID000152659
Druglavendustin C6

ENO1 ENO2 ENO3

2.45e-0572053CID000126839
DrugCPEP

ENO1 ENO2 ENO3

2.45e-0572053CID000360637
Drugenoxacin

CYP1A2 ENO1 ENO2 ENO3

2.76e-05202054CID000003229
Drugmacrophomate

ENO1 ENO2 ENO3

3.90e-0582053CID010889109
Druglosartan

CYP1A2 ITGB3 ACTL7A FAT2 AGT HSPG2 COL12A1 COL17A1 PNMT HAT1 TGFBI VCAN ENPEP

4.14e-0537820513CID000003961
DrugAC1L19IJ

ENO1 ENO2 ENO3

5.81e-0592053CID000000562
DrugAC1L1A4W

ENO1 ENO2 ENO3

5.81e-0592053CID000000837
Drug3-isoreserpine

ADCY9 VPS13A ABCD4 ABCC10 HTR1D PNMT SLC17A5 SF3B3 SLC18A2

5.88e-051902059CID000005052
DrugIopanoic acid [96-83-3]; Down 200; 7uM; MCF7; HT_HG-U133A

DAPK3 RUSC2 MCF2L AOC2 TGFBI MARK4 WDFY3 PATJ ENPEP

6.91e-0519420595448_DN
DrugIN1076

SRMS ITGB3 STAT3 MTOR ENO1 ENO2 ENO3

7.06e-051122057CID000005309
DrugHarmaline hydrochloride dihydrate [6027-98-1]; Up 200; 14uM; MCF7; HT_HG-U133A

SLC17A2 APOBR MCF2L HSPG2 HIPK2 RGS12 MARK4 PAX5 IL4R

7.19e-0519520592805_UP
Drug6-mercaptopurine monohydrate; Down 200; 10uM; PC3; HG-U133A

CTNNAL1 TRPS1 BRCA1 MCF2L HIPK2 HIVEP3 ARHGAP5 SMO RAB11FIP3

7.19e-051952059667_DN
DrugPiroxicam [36322-90-4]; Down 200; 12uM; PC3; HT_HG-U133A

DAPK3 RUSC2 BNC1 NFKB2 PLXNA1 HIPK2 ATP13A2 DENND3 SLC17A5

7.47e-0519620592089_DN
DrugSalbutamol [18559-94-9]; Down 200; 16.8uM; MCF7; HT_HG-U133A

DAPK3 DYNC2H1 DOCK9 SLC17A5 SF3B3 MARK4 WDFY3 ENPEP IL4R

7.77e-0519720592306_DN
DrugNefopam hydrochloride [23327-57-3]; Up 200; 13.8uM; MCF7; HT_HG-U133A

ITGB3 PTPRS ACSBG2 WDR62 HIPK2 ADGRA2 DENND3 VCAN DDX28

7.77e-0519720593627_UP
DrugGliclazide [21187-98-4]; Up 200; 12.4uM; PC3; HT_HG-U133A

MAP1A ADCY9 SCN9A MCF2L DOCK9 PBRM1 SLC18A2 PATJ RAB11FIP3

7.77e-0519720595089_UP
DrugHQ-cysteine

AIFM1 ENPEP

8.07e-0522052CID000161996
DrugGuanabenz acetate [23256-50-0]; Up 200; 13.8uM; MCF7; HT_HG-U133A

ITGB3 DES HEG1 PTPRS HIVEP3 TGFBI VCAN MARK4 PATJ

8.08e-0519820591544_UP
DrugMifepristone [84371-65-3]; Up 200; 9.4uM; MCF7; HT_HG-U133A

IMPG1 MAP1A APOBR ITGB3 RUSC2 ABCD4 ACSBG2 DYNC2H1 VCAN

8.08e-0519820593185_UP
Drugpefloxacin

CYP1A2 ENO1 ENO2 ENO3

8.17e-05262054CID000051081
Drugpyrene-4,5-dione

ENO1 ENO2 ENO3

8.24e-05102053CID000160814
DrugL-fuconic acid

ENO1 ENO2 ENO3

8.24e-05102053CID000345732
Drugphosphoenolthiopyruvate

ENO1 ENO2 ENO3

8.24e-05102053CID000194910
Drugxylonate

ENO1 ENO2 ENO3

8.24e-05102053CID000010264
Drug15(S)-15-methyl Prostaglandin E2; Down 200; 10uM; PC3; HT_HG-U133A

ITGB3 RUSC2 HEG1 WDR62 HHLA1 HIVEP3 ARAP3 VCAN WDFY3

8.40e-0519920597494_DN
DrugCalciferol [50-14-6]; Down 200; 10uM; HL60; HT_HG-U133A

CYP1A2 TRPS1 RUSC2 DES PLXNA1 DYNC2H1 MAP3K14 FLVCR2 HIVEP3

8.40e-0519920592442_DN
DrugAmiloride hydrochloride dihydrate [17440-83-4]; Up 200; 13.2uM; MCF7; HT_HG-U133A

OR7E24 CADM4 DAPK2 DAPK3 ITGB3 DOCK9 ADGRA2 DENND3 RAB11FIP3

8.73e-0520020594109_UP
DrugAC1NBU2S

NOP9 NFKB2 AGT RELA ADGRA2 AIFM1 CACNA2D3

9.30e-051172057CID004473765
DrugChalcone

CYP1A2 STAT3 HAT1 RELA

9.52e-05272054ctd:D002599
Drugallo-threonine

SPNS1 DAPK1 DAPK3 TRIB3 ENO1 ENO2 ENO3

1.04e-041192057CID000000205
DrugSM 164

NFKB2 MAP3K14 RELA

1.13e-04112053ctd:C533467
Drugcandesartan

SLC17A2 ITGB3 NFKB2 AGT HAT1 RELA SLC17A1 ENPEP

1.14e-041622058CID000002541
DrugGlu-Ala

ENO1 ENO2 ENO3 ENPEP

1.27e-04292054CID000100098
Drug1-phenylpentan-3-amine

DES ENO1 ENO2 ENO3

1.27e-04292054CID005195771
Drugmucic acid

CYP1A2 SLC17A5 SLC17A1 ENO1 ENO2 ENO3

1.45e-04882056CID000000607
Drugnicaraven

SPNS1 MCF2L MAP3K14 MTOR

1.46e-04302054CID000071234
DrugLG61

ENO1 ENO2 ENO3

1.49e-04122053CID000520177
Diseasecortical thickness

MYCBP2 MARK3 TRPS1 MBD6 STAU1 FZD9 BNC1 PTPRF ABCC10 HSPG2 COL12A1 HTR1D DOCK9 SLA ADGRA2 ATP13A2 DENND3 FURIN VCAN KCTD3 SSH2 CACNA2D3

5.42e-06111319622EFO_0004840
DiseaseExocrine pancreatic insufficiency

CELA3B MTOR

4.39e-0521962C0267963
DiseaseCarcinoma

TRPS1 STAT3 BLM DES BRCA1 FURIN ENO1

1.18e-041641967C0007097
Disease1,3,7-trimethylurate measurement

CYP1A2 PTPRF FRAS1

1.24e-04151963EFO_0021172
Diseasemean arterial pressure

SLC17A2 CYP1A2 DAPK1 AGT ABCC10 HECTD4 HIPK2 HIVEP3 ARAP3 FURIN MARK4 ENPEP

1.38e-0449919612EFO_0006340
Diseasevisual impairment and progressive phthisis bulbi (implicated_via_orthology)

MARK3 MARK4

2.61e-0441962DOID:0070356 (implicated_via_orthology)
Diseaseneuroimaging measurement

CYP1A2 DCHS2 CTNNAL1 MARK3 TRPS1 MBD6 ARHGEF11 FZD9 BRCA1 HTR1D DOCK9 BRSK2 SLC13A3 ATP13A2 DENND3 FURIN VCAN SSH2

2.97e-04106919618EFO_0004346
DiseaseAnimal Mammary Neoplasms

TRPS1 STAT3 DES BRCA1 FURIN ENO1

3.85e-041421966C0024667
DiseaseMammary Carcinoma, Animal

TRPS1 STAT3 DES BRCA1 FURIN ENO1

3.85e-041421966C1257925
DiseaseNeurodevelopmental Disorders

BRSK2 HIVEP3 PAX5 WDFY3 CACNA2D3

3.98e-04931965C1535926
DiseaseAgents acting on the renin-angiotensin system use measurement

CYP1A2 TRPS1 ADCY9 AGT ABCC10 HIPK2 RGS12 SF3B3 ENPEP

4.30e-043351969EFO_0009931
Diseaseprimary progressive multiple sclerosis (is_implicated_in)

ADAMTS14 IL4R

4.33e-0451962DOID:0050784 (is_implicated_in)
DiseaseUreteral obstruction

AGT HIPK2 RELA

5.27e-04241963C0041956
Diseasepancreatic cancer (is_marker_for)

MUC16 RELA SMO MUC6 IL4R

5.81e-041011965DOID:1793 (is_marker_for)
DiseaseMammary Neoplasms, Experimental

TRPS1 STAT3 DES BRCA1 FURIN ENO1

6.12e-041551966C0024668
DiseaseLiver Cirrhosis, Experimental

SLC17A2 CYP1A2 ITGB3 AGT NFKBIE RAB40B COL12A1 RTN4 RELA LCN2 SLA TRIB3 SLC17A1 ENPEP

7.11e-0477419614C0023893
DiseaseCarcinomatosis

TRPS1 STAT3 DES BRCA1 FURIN ENO1

7.97e-041631966C0205699
DiseaseCarcinoma, Spindle-Cell

TRPS1 STAT3 DES BRCA1 FURIN ENO1

7.97e-041631966C0205697
DiseaseUndifferentiated carcinoma

TRPS1 STAT3 DES BRCA1 FURIN ENO1

7.97e-041631966C0205698
DiseaseAnaplastic carcinoma

TRPS1 STAT3 DES BRCA1 FURIN ENO1

7.97e-041631966C0205696
DiseaseUlcerative Colitis

IRGM STAT3 HERC2 RELA

8.28e-04631964C0009324
DiseaseMalignant neoplasm of breast

STAT3 DES NOP9 BRCA1 SNX32 MROH7 HERC2 MICAL1 DYNC2H1 RELA CUBN HELQ PBRM1 ARAP3 MTOR ENO1 ENPEP

8.71e-04107419617C0006142
DiseaseColorectal Carcinoma

CYP1A2 HTR3C TOMM40L PTPRS VPS13A ABCD4 RTN4 HAT1 CUBN HIVEP3 ARAP3 ZNF540 DCHS1

8.87e-0470219613C0009402
Diseasehyperuricemia (implicated_via_orthology)

STAT3 SLC2A9

9.02e-0471962DOID:1920 (implicated_via_orthology)
Diseaseresponse to interferon-beta

DENND3 GRHL3

9.02e-0471962GO_0035456
Diseaseremission

HSPG2 CELA3B

9.02e-0471962EFO_0009785
DiseaseIschemic stroke, factor VII measurement

MCF2L HECTD4 PIGU

9.29e-04291963EFO_0004619, HP_0002140
DiseaseBreast Carcinoma

STAT3 DES NOP9 BRCA1 SNX32 HERC2 DYNC2H1 RELA PBRM1 MTOR ENO1

1.00e-0353819611C0678222
DiseaseOvarian Mucinous Adenocarcinoma

DAPK3 MAP3K14 MTOR

1.13e-03311963C1335167
Diseaserenal cell carcinoma (is_implicated_in)

STAT3 RELA PBRM1 IL4R

1.17e-03691964DOID:4450 (is_implicated_in)
Diseasemonocyte percentage of leukocytes

MARK3 TRPS1 ARHGEF11 ADCY9 BRCA1 NFKBIE CFAP206 MAP3K14 CELA3B DNAH12 MARK4 WDFY3 SSH2

1.28e-0373119613EFO_0007989
DiseaseBrain Tumor, Primary

DAPK1 RELA SMO

1.36e-03331963C0750974
DiseasePrimary malignant neoplasm of brain

DAPK1 RELA SMO

1.36e-03331963C0750979
DiseaseRecurrent Brain Neoplasm

DAPK1 RELA SMO

1.36e-03331963C0750977
DiseaseBenign neoplasm of brain, unspecified

DAPK1 RELA SMO

1.36e-03331963C0496899
DiseaseNeoplasms, Intracranial

DAPK1 RELA SMO

1.36e-03331963C1527390
Diseasejoint hypermobility measurement

FNDC1 COL12A1 VCAN

1.36e-03331963EFO_0007905
Diseasemitral valve prolapse (is_implicated_in)

AGT DCHS1

1.53e-0391962DOID:988 (is_implicated_in)
DiseaseSarcomatoid Renal Cell Carcinoma

DAPK1 RELA PBRM1 MTOR IL4R

1.68e-031281965C1266043
DiseaseChromophobe Renal Cell Carcinoma

DAPK1 RELA PBRM1 MTOR IL4R

1.68e-031281965C1266042
DiseaseCollecting Duct Carcinoma of the Kidney

DAPK1 RELA PBRM1 MTOR IL4R

1.68e-031281965C1266044
DiseasePapillary Renal Cell Carcinoma

DAPK1 RELA PBRM1 MTOR IL4R

1.68e-031281965C1306837
DiseaseRenal Cell Carcinoma

DAPK1 RELA PBRM1 MTOR IL4R

1.68e-031281965C0007134
DiseaseAtrophic

CYP1A2 STAT3

1.91e-03101962C0333641
DiseaseMalignant neoplasm of brain

DAPK1 RELA SMO

2.05e-03381963C0153633
Diseasecolon cancer (biomarker_via_orthology)

STAT3 LCN2 MTOR

2.21e-03391963DOID:219 (biomarker_via_orthology)
DiseaseBrain Neoplasms

DAPK1 RELA SMO

2.21e-03391963C0006118
Diseaseforced expiratory volume, body mass index

HECTD4 PCDHA1

2.32e-03111962EFO_0004314, EFO_0004340
DiseaseInherited neuropathies

KCNC3 SCN9A TDP1

2.38e-03401963C0598589
DiseaseSchizophrenia

CYP1A2 CSMD2 ARHGEF11 ITGB3 BRCA1 RTN4 RELA LCN2 RGS12 PBRM1 WDR11 MTOR SLC18A2 ENO2

2.44e-0388319614C0036341
Diseaseretinal vasculature measurement

CYP1A2 HERC2 SYT13 HSPG2 HIPK2 NIBAN2 FLVCR2 DENND3 CELA3B PATJ

2.52e-0351719610EFO_0010554
DiseaseNeoplasm of uncertain or unknown behavior of breast

BRCA1 HERC2 PBRM1

2.56e-03411963C0496956
DiseaseBreast adenocarcinoma

BRCA1 HERC2 PBRM1

2.56e-03411963C0858252
DiseaseNodular glomerulosclerosis

AGT RELA TGFBI

2.56e-03411963C0017667
Diseaseuric acid measurement

SPNS1 ADCY9 FRAS1 SLC2A9 DYNC2H1 HECTD4 CUBN NSUN3 SLC17A1 MARK4 CACNA2D3

2.68e-0361019611EFO_0004761
Diseasehyperinsulinism (is_implicated_in)

PTPRF AGT

2.77e-03121962DOID:2018 (is_implicated_in)
DiseasePrecursor B-Cell Lymphoblastic Leukemia-Lymphoma

STAT3 PAX5

2.77e-03121962C0023485
Diseaseeye color

HERC2 MUC16 HIVEP3 ENPEP

3.09e-03901964EFO_0003949
DiseaseDiabetic Nephropathy

AGT RELA TGFBI

3.13e-03441963C0011881
DiseaseConventional (Clear Cell) Renal Cell Carcinoma

DAPK1 RELA PBRM1 MTOR IL4R

3.16e-031481965C0279702
Diseasejuvenile polyposis syndrome (implicated_via_orthology)

HIVEP1 HIVEP3

3.26e-03131962DOID:0050787 (implicated_via_orthology)
Diseaseskin melanoma (is_marker_for)

STAT3 AGT

3.26e-03131962DOID:8923 (is_marker_for)
DiseaseAcute Promyelocytic Leukemia

DAPK2 STAT3 SMO

3.55e-03461963C0023487
Diseasevital capacity

SLC17A2 STAU1 PLXNA1 HSPG2 MICAL1 SLC2A9 EPB41L4B MAP3K14 PCDHA1 PIGU ATP13A2 KCNH3 CELA3B HMCN1 AIFM1 PATJ CACNA2D3

3.78e-03123619617EFO_0004312
Diseasegastric ulcer (implicated_via_orthology)

AGT MUC6

3.79e-03141962DOID:10808 (implicated_via_orthology)
DiseaseMalformations of Cortical Development

WDR62 MTOR

3.79e-03141962C1955869
Diseasetrimethylamine-N-oxide measurement

RTN4 CUBN

3.79e-03141962EFO_0010541
Diseaseneuronal ceroid lipofuscinosis (implicated_via_orthology)

SPNS1 ATP13A2

3.79e-03141962DOID:14503 (implicated_via_orthology)
Diseaseactinic keratosis

TRPS1 HERC2

3.79e-03141962EFO_0002496
DiseaseCortical Dysplasia

WDR62 MTOR

3.79e-03141962C0431380
Diseasebrain measurement, neuroimaging measurement

DCHS2 MARK3 TRPS1 MBD6 BRSK2 ATP13A2 DENND3 PBRM1 VCAN SSH2

3.91e-0355019610EFO_0004346, EFO_0004464
DiseaseNon-Small Cell Lung Carcinoma

DAPK1 STAT3 MTOR ENO1 ENO2

3.95e-031561965C0007131
Diseasetransient cerebral ischemia (biomarker_via_orthology)

ITGB3 AGT LCN2 MTOR AIFM1

4.06e-031571965DOID:224 (biomarker_via_orthology)
Diseasebirth weight, pelvic organ prolapse

DOCK9 ARAP3 CACNA2D3

4.25e-03491963EFO_0004344, EFO_0004710
DiseaseNephrosis

DES AGT

4.35e-03151962C0027720
Diseasechenodeoxycholate measurement

SLC22A20P HMCN1

4.35e-03151962EFO_0010471
Diseaseblood cobalt measurement

USH2A SLC2A9 MUC16 ADAMTS14

4.67e-031011964EFO_0007577
Diseasegout, hyperuricemia

SLC2A9 NSUN3

4.95e-03161962EFO_0004274, EFO_0009104
Diseaseneutrophil count

HIVEP1 MYCBP2 RIPOR3 BRCA1 SNX32 CD300LF DYNC2H1 HECTD4 PCDHA1 LCN2 HIVEP3 CELA3A SLC25A1 FURIN MARK4 SSH2 MFSD13A ENO1

5.11e-03138219618EFO_0004833
Diseaseglucose-dependent insulinotropic peptide measurement

SLC41A3 SLC13A3 CACNA2D3

5.30e-03531963EFO_0008464
Diseaseserum alanine aminotransferase measurement

MARK3 TRPS1 SRMS FZD9 COL12A1 EPB41L4B HECTD4 PIGU RGS12 NSUN3 MARK4 GRHL3 PATJ

5.58e-0386919613EFO_0004735
DiseaseHepatomegaly

CYP1A2 DAPK2 RELA

5.58e-03541963C0019209
Diseasepre-malignant neoplasm (biomarker_via_orthology)

STAT3 SMO

5.59e-03171962DOID:0060071 (biomarker_via_orthology)
DiseaseLeukemia, Myelocytic, Acute

DAPK1 STAT3 BLM BRCA1 ENO2

6.10e-031731965C0023467
Diseaseovarian cancer (is_implicated_in)

STAT3 BRCA1 MUC16

6.18e-03561963DOID:2394 (is_implicated_in)
Diseasepeak expiratory flow

CYP1A2 PTPRF MLLT6 MICAL1 DOCK9 PIGU ATP13A2 SSH2 CACNA2D3

6.32e-034981969EFO_0009718
DiseaseAlzheimer's disease (implicated_via_orthology)

HIVEP1 TOMM40L HIVEP3

6.49e-03571963DOID:10652 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
AGAGEVLLSISYLPA

SYT13

286

Q7L8C5
ALYTTSSGGPEDIVL

TDRD5

676

Q8NAT2
SLDIPIGELYGLSES

ACSBG2

411

Q5FVE4
LPLSNLYETLGVVGS

TGFBI

101

Q15582
LPGTSYEELLSLLRG

COL17A1

1156

Q9UMD9
ITYILLSGASPFLGD

DAPK1

206

P53355
LSLESPLLGAGIYTS

MLLT6

541

P55198
LGPLYTNITADIGTD

B4GALT3

331

O60512
ILGGLSYSLPGLTDS

AADACL2

301

Q6P093
GYASLELPGDSTLLS

ARAP3

246

Q8WWN8
LTDSTGVILSQSYPG

CSMD2

2361

Q7Z408
FPYSGDKILVEGIST

VCAN

656

P13611
ESSPGQLSISLRYEG

ABL2

201

P42684
VSALGSVPLISITGY

BTNL8

131

Q6UX41
GILGSVQYTFSSLPL

BPIFB4

356

P59827
GGILASIYLPKSLTE

ADGRG4

2601

Q8IZF6
SLYSPGVQLGALVTT

ADGRA2

1011

Q96PE1
GYEAIGLVDSSLPTV

AIFM1

491

O95831
TIILTISPDNYGLGS

ADGRG2

751

Q8IZP9
SLESYNSGPLSEGTI

BNC1

841

Q01954
SGAYVALTLLGSSPS

ARHGEF11

111

O15085
LFGTYLTKNGSEIPS

ARL9

156

Q6T311
SIEGLGKSCSPVYLG

CFAP418

96

Q96NL8
TPSGLTAYISSEGRI

HTR3C

136

Q8WXA8
GVYGDLSPAELSTLV

ABCD4

296

O14678
FLLTEGRPGYLEIST

DENND3

746

A2RUS2
PSGASTGIYEALELR

ENO2

36

P09104
LSGKLSDYGVTVPCS

ADAMTS14

31

Q8WXS8
SPTAVFGTLASLYLG

AGT

126

P01019
SYVLLRSGLGSPTDI

CFAP206

136

Q8IYR0
PLLGGYTVLASSGST

GMEB2

426

Q9UKD1
SYVTLIPGSSYGISL

MROH7

296

Q68CQ1
TQYLLTLLETDGGLP

R3HDM4

76

Q96D70
PAGIDYKTTTILLDG

RAB40B

46

Q12829
SLYNITLKATDGGTP

PCDHGA7

416

Q9Y5G6
SLSGAGSYLALPALT

HSPG2

3931

P98160
DLTKYLDPSGLGVIS

RAB11FIP3

241

O75154
KGRPDLYTSTLITDG

CYP1A2

106

P05177
YLELIGNSLPGTTAK

NIBAN2

131

Q96TA1
IVTGRDLASTTLPGY

PAX5

301

Q02548
ELLGGPSLRSAYITS

KCNH3

441

Q9ULD8
TIFALAYVLLTSPGG

AOC2

16

O75106
LVPSYTGGSLLEDLA

MBD3L1

96

Q8WWY6
TGYSLATSQVTLPLG

MUC16

9666

Q8WXI7
KDIGVISLPYTSNGL

MUC6

116

Q6W4X9
PGLVGLSLSYALSLT

ABCC10

1181

Q5T3U5
TILYTLTGPGSELFS

DCHS1

1251

Q96JQ0
EGAVLYISPSGTELS

MBD6

31

Q96DN6
PGGILVYSTCTLSKA

NSUN3

256

Q9H649
YLSTRGSSVDGSPLL

NOP9

306

Q86U38
GTVTEGSSPAYLKEI

PBRM1

171

Q86U86
PSYGTLLRISGSEVE

FRAS1

1756

Q86XX4
TQGLPAEYLLSAGTK

HIPK2

416

Q9H2X6
LSSKGSSGAPVYVDL

MAP1A

2681

P78559
SYTLVSKLGLPSEGI

MAGEB6

261

Q8N7X4
LISKLYPGESIGQTS

HERC2

1061

O95714
IPTSDYSAISQLALG

IMPG1

481

Q17R60
TVPGATSYLLTAEDG

FNDC7

51

Q5VTL7
LRLESPGEASSGLYS

HMCN2

1681

Q8NDA2
GTFLSSLLKSPYQGI

LIPT1

186

Q9Y234
SLTYTLSLLGGPEAE

NFKBIE

216

O00221
LPGTGSATTTLENYL

IRGM

91

A1A4Y4
GEDKSSKGYILPLST

KIAA2026

1606

Q5HYC2
GIYSVTFTLLSGPSR

BRSK2

606

Q8IWQ3
GSGEDLYILTGTVPS

ENDOD1

191

O94919
YSDSLLTLPAIVGIG

PLXNA1

1236

Q9UIW2
KTGVLTVTGPLDYES

FAT2

2221

Q9NYQ8
SYLLPSGGSVTLSES

EEF2KMT

111

Q96G04
ITYILLSGASPFLGE

DAPK3

206

O43293
AAETGSGKTLSYLLP

DDX28

171

Q9NUL7
VGYDLTPDSGTTLRK

DNAH12

786

Q6ZR08
SEILLGYLGVPAASS

MIGA2

561

Q7L4E1
VVAGSDPLGLIAYLS

MICAL1

591

Q8TDZ2
ELTPSSGDGLYLLTM

ENPEP

176

Q07075
LGVTAEYSPASRSLG

HEG1

931

Q9ULI3
ISSGLNILYPGETEI

HECTD4

341

Q9Y4D8
EGLSLLDLGVSPYSG

PIGU

46

Q9H490
GALGDYLSFTIPLGT

PSENEN

86

Q9NZ42
GIPTYVLLNTSGIST

HMCN1

341

Q96RW7
DITTTRYSIGGLSPN

PTPRS

381

Q13332
IDGVILYSLGTSSPF

DCHS2

2911

Q6V1P9
DIGANALLTYTLSPS

PCDHA1

161

Q9Y5I3
DSEGVATLPLSYRLG

FAM171A2

76

A8MVW0
EFTLGNIKSYPGLTS

LCN2

111

P80188
LVPGTDYGTQESISL

BRCA1

771

P38398
QDLEGTPYLESGISL

BRCA1

1556

P38398
TDYVEIGSSSILGSP

CUBN

871

O60494
FVLVPLSGYLVLGSS

FZD9

401

O00144
INSLLSSGEVPGLYT

DYNC2H1

2726

Q8NCM8
PSGASTGIYEALELR

ENO1

36

P06733
YALETGLAGIPSSDS

EXOC5

461

O00471
YGTLTIGTSIDPLSS

ATP13A2

16

Q9NQ11
LATGLSGLYSSLPTK

FHIP1A

246

Q05DH4
SGLYSSLPTKLEEKG

FHIP1A

251

Q05DH4
DPLVDSLGSGIVYSA

IL4R

701

P24394
TLLHTYSVLSPTGGE

HAT1

141

O14929
GPSKLEAGSVDSYLL

GRHL3

151

Q8TE85
ILPFYLEVGLSGLSS

KCNC1

286

P48547
KLTSLDIPATYLTGD

BLM

726

P54132
LLGAISGIASPYTTS

DOCK9

1226

Q9BZ29
SLYLFTRGEGPLKTS

CTNNAL1

606

Q9UBT7
GLSVPLTDQGTTLYL

COL12A1

2191

Q99715
YTDIKGTPFSLGVAL

CACNA2D3

606

Q8IZS8
SPSKGYTLQIFELTG

COL20A1

86

Q9P218
ITYILLSGASPFLGD

DAPK2

216

Q9UIK4
LSSLLLVAVASGYGP

CELA3A

6

P09093
LTYPGDTTSALVDGL

FNDC1

411

Q4ZHG4
GTLTKFTLVLYGTAP

FURIN

561

P09958
SLPKEDISYASLTLG

CD300LF

241

Q8TDQ1
IPGYSRSLTTGQLSD

DLGAP3

451

O95886
TTRTPSSYGAGELLD

DES

76

P17661
LTLPGLVSADNGTYT

CADM4

276

Q8NFZ8
TPANYLIGSLATTDL

HTR1D

71

P28221
PLTAGVIGTTKLLYD

ADCY9

1171

O60503
LSSLLLVAVASGYGP

CELA3B

6

P08861
YPESEGISSGLLNIS

FLVCR2

431

Q9UPI3
VILYTLVSGSLPFDG

MARK3

241

P27448
SLGVILYTLVSGSLP

MARK4

241

Q96L34
TYLTSIPSLQDAGIG

MCF2L

116

O15068
NYSELIPGTTVGVLS

ITGB3

346

P05106
AKIPYVTLSTGGIET

SLC2A9

351

Q9NRM0
IPVAGLSDSGLYTVV

IGFN1

1006

Q86VF2
PSGASTGIYEALELR

ENO3

36

P13929
IYSLPTSGGKTLVAE

HELQ

356

Q8TDG4
PVSYLGSKFLGSDLE

CCDC8

131

Q9H0W5
GLTAPLVTTLGEYST

SLC22A20P

471

A6NK97
ISIPYSASIGGTATL

SLC13A3

236

Q8WWT9
ISYAGAQLGTVISLP

SLC17A5

201

Q9NRA2
EYSLGLTPTGILIFE

EPB41L4B

286

Q9H329
VDVGGSEPASLSYLS

EXOSC3

131

Q9NQT5
VPITSYDTAGSFLLL

KCTD3

316

Q9Y597
LSTGSILLGLSYVAP

MFSD13A

301

Q14CX5
LLTTVGSLLPGITYS

PTPRF

471

P10586
LAGIGYSSAVTPKVL

OR5B17

66

Q8NGF7
ILLGPLSVTGASYVA

OR6A2

211

O95222
LGKSLLTGDYIPGTE

MAP3K14

546

Q99558
VRSIYDDISSPGLGS

NUP35

91

Q8NFH5
TSDEIIGLSYGVVSP

OR13D1

301

Q8NGV5
VGLSPALTAVLYDLS

MTOR

511

P42345
YDLSSAISVLVPLGG

MTA3

246

Q9BTC8
AISLSTGRESYIPGI

SLA

61

Q13239
ALSLGQSTDSLGTYP

SMG8

696

Q8ND04
LTLTEYRLHGTGSLP

RUSC2

841

Q8N2Y8
YLGNLSTVLPTEGTL

RTN4

251

Q9NQC3
PIINYTFTSGLSGVL

HHLA1

211

C9JL84
TPLIQYDTSTGLGLV

USH2A

5006

O75445
YDTSTGLGLVLTTPG

USH2A

5011

O75445
LGEAVTGLLLIYPTS

TEX47

81

Q8TBZ9
YGDTPTVSIKGILTL

TC2N

256

Q8N9U0
GSSYREGLTPVLSLL

RIC8B

356

Q9NVN3
GTGLVGYLSSAVLPS

OR7E24

271

Q6IFN5
SPDIQGIILSSTSYG

SLC17A1

76

Q14916
YPSIGQLKTLDLSGT

PRAMEF20

316

Q5VT98
VTLVANTLGYSDLGP

SCN9A

1271

Q15858
SISYDGTVRKESGIP

TRGV9

71

Q99603
PYLTGLGDLLGSSSV

SLC41A3

446

Q96GZ6
TPGAIGLYTLHVTID

MYCBP2

2416

O75592
IIYTEPVDLSLGTLG

PHYHIP

286

Q92561
PSYTISIVGLSGTEK

ARHGAP5

11

Q13017
AGTTAASLTYPLDLV

SLC25A42

141

Q86VD7
TPQTSLGSLSDLIYA

SEBOX

166

Q9HB31
IRPSESSLGGYSLSV

SRMS

146

Q9H3Y6
LLLPGITGSSQDTYV

ABHD1

126

Q96SE0
PSITGRLDYAGSDLT

ACTL7A

236

Q9Y615
ILYTSGTTGLPKGVI

ACSS3

296

Q9H6R3
SLGTFVSYLLGDAVP

APOBR

21

Q0VD83
IDIGSGPTVYQLLSA

PNMT

76

P11086
YTQASLGLLTPVSGT

TRPS1

806

Q9UHF7
DLSETNVYLIGSTPG

TDP1

346

Q9NUW8
YSLPGTLAKSEILET

ZNF35

91

P13682
NLVSLGYSGSKPDVI

ZNF540

41

Q8NDQ6
GYSGSKPDVITLLEQ

ZNF540

46

Q8NDQ6
LSVYEGDTLLGTASP

VPS13A

2006

Q96RL7
SLTTYGVSELKPAGI

WDFY3

341

Q8IZQ1
IVGYLGSIELPSTSS

RGS12

231

O14924
ARELLYGGTSPTAET

STAU1

456

O95793
YLLPRAGLELTSSEG

SSH2

1356

Q76I76
LGGPRATSILSYLSD

RIPOR3

371

Q96MK2
LSTVLPGLTYLTVAG

SAGE1

551

Q9NXZ1
EASGIYVKSIIPGSA

PATJ

391

Q8NI35
TTLAEKLLGPGVNYS

STAT3

526

P40763
VGPEILSSRASYSGK

TRIB3

226

Q96RU7
SGTGRSYTTDPLLSL

VSTM2B

256

A6NLU5
GVGEASYSTIAPTLI

SPNS1

161

Q9H2V7
LKELSDPAGAIIYTS

PFAS

526

O15067
LPSYDEAVSGGLSAL

SUSD4

376

Q5VX71
SSINYGIILTLIPSG

SLC17A2

96

O00624
PLGSVEKDTGSALSY

HIVEP3

1946

Q5T1R4
YTLIPTSILLGLGAA

UNC93A

91

Q86WB7
GLSSLLYGSIPKAAV

SLC25A1

86

P53007
AISPSQGSYEEGTIL

PKHD1L1

1071

Q86WI1
KTTLIPGGSESLVYT

SF3B3

1106

Q15393
SVLPYGATSTLLAGD

SMO

81

Q99835
EYSKPETGLTLLASA

WDR62

541

O43379
GSLGLAFYLPLVVTT

TMEM81

11

Q6P7N7
KSGIIPGSYSFESVL

UBR3

816

Q6ZT12
SAALYGIPEISSTGK

ZNF608

121

Q9ULD9
YTATLTLGNPDLIGE

TOMM40L

146

Q969M1
CSLGTKEPTYLLGID

WDR89

16

Q96FK6
PLLAVGTSNGSVLVY

WDR11

486

Q9BZH6
DYIPISAALSSLGTQ

SNX32

241

Q86XE0
GVAFLPASISYLIGT

SLC18A2

331

Q05940
YTGPGTVRISLVTKD

RELA

66

Q04206
KLLSPRSLGSTDSGY

HIVEP1

661

P15822
SLPLTYGVASSVGTI

TBRG1

101

Q3YBR2
LEGLYLLTDGKPDTS

VWA3A

1051

A6NCI4
PFYLEVGLSGLSSKA

KCNC3

391

Q14003
PYSLETLKGGTILGT

SLC4A1AP

166

Q9BWU0
PLTYSLEKSVIGSGT

MYOM3

531

Q5VTT5
TSPSGSLLRSYELAG

NFKB2

811

Q00653