Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	Mon1-Ccz1 complex	CCZ1B CCZ1	6.28e-05	5	53	2	GO:0035658
GeneOntologyCellularComponent	basolateral plasma membrane	ARRB2 SLCO4C1 SLCO2B1 DSTYK SLC16A7 SLC38A3	1.54e-04	320	53	6	GO:0016323
GeneOntologyCellularComponent	basal plasma membrane	ARRB2 SLCO4C1 SLCO2B1 DSTYK SLC16A7 SLC38A3	2.65e-04	354	53	6	GO:0009925
GeneOntologyCellularComponent	basal part of cell	ARRB2 SLCO4C1 SLCO2B1 DSTYK SLC16A7 SLC38A3	3.77e-04	378	53	6	GO:0045178
GeneOntologyCellularComponent	semaphorin receptor complex	PLXNC1 PLXNB2	4.83e-04	13	53	2	GO:0002116
MousePheno	uremia	PTTG1 SLCO2B1 MTMR2 PDZD8 ZDHHC13 SLC38A3 PTTG2 MOCOS	2.73e-05	437	40	8	MP:0009644
Domain	DUF1712	CCZ1B CCZ1	7.60e-06	2	52	2	PF08217
Domain	Securin_separation-inh_met	PTTG1 PTTG2	7.60e-06	2	52	2	IPR018008
Domain	DUF1712_fun	CCZ1B CCZ1	7.60e-06	2	52	2	IPR013176
Domain	Securin	PTTG1 PTTG2	7.60e-06	2	52	2	PF04856
Domain	Securin_separation_inhibitor	PTTG1 PTTG2	7.60e-06	2	52	2	IPR006940
Domain	Ig_E-set	ARRB2 PLXNC1 PLXNB2 SNRNP200	2.00e-04	104	52	4	IPR014756
Domain	Plexin_cytopl	PLXNC1 PLXNB2	2.70e-04	9	52	2	PF08337
Domain	Plexin_cytoplasmic_RasGAP_dom	PLXNC1 PLXNB2	2.70e-04	9	52	2	IPR013548
Domain	Plexin	PLXNC1 PLXNB2	2.70e-04	9	52	2	IPR031148
Domain	OA_transporter	SLCO4C1 SLCO2B1	4.93e-04	12	52	2	IPR004156
Domain	OATP	SLCO4C1 SLCO2B1	4.93e-04	12	52	2	PF03137
Domain	-	LGALS12 WDFY3 ADGRV1	2.35e-03	95	52	3	2.60.120.200
Domain	IPT	PLXNC1 PLXNB2	2.55e-03	27	52	2	SM00429
Domain	TIG	PLXNC1 PLXNB2	3.36e-03	31	52	2	PF01833
Domain	Sema	PLXNC1 PLXNB2	3.36e-03	31	52	2	SM00630
Domain	Semap_dom	PLXNC1 PLXNB2	3.36e-03	31	52	2	IPR001627
Domain	Sema	PLXNC1 PLXNB2	3.36e-03	31	52	2	PF01403
Domain	SEMA	PLXNC1 PLXNB2	3.36e-03	31	52	2	PS51004
Domain	PSI	PLXNC1 PLXNB2	3.57e-03	32	52	2	PF01437
Domain	IPT	PLXNC1 PLXNB2	3.57e-03	32	52	2	IPR002909
Domain	Plexin_repeat	PLXNC1 PLXNB2	3.57e-03	32	52	2	IPR002165
Domain	MFS_dom	SLCO4C1 SLCO2B1 SLC16A7	6.18e-03	134	52	3	IPR020846
Domain	PSI	PLXNC1 PLXNB2	6.67e-03	44	52	2	IPR016201
Domain	PSI	PLXNC1 PLXNB2	7.28e-03	46	52	2	SM00423
Pubmed	Mice lacking pituitary tumor transforming gene show testicular and splenic hypoplasia, thymic hyperplasia, thrombocytopenia, aberrant cell cycle progression, and premature centromere division.	PTTG1 PTTG2	6.83e-06	3	53	2	11682618
Pubmed	PTTG is a secretory protein in human pituitary adenomas and in mouse pituitary tumor cell lines.	PTTG1 PTTG2	6.83e-06	3	53	2	17652795
Pubmed	Pituitary Tumor Transforming Gene 1 Orchestrates Gene Regulatory Variation in Mouse Ventral Midbrain During Aging.	PTTG1 PTTG2	6.83e-06	3	53	2	33173537
Pubmed	Pituitary tumor transforming gene (PTTG) transforming and transactivation activity.	PTTG1 PTTG2	6.83e-06	3	53	2	10713046
Pubmed	Pituitary tumor transforming gene-null male mice exhibit impaired pancreatic beta cell proliferation and diabetes.	PTTG1 PTTG2	6.83e-06	3	53	2	12626748
Pubmed	PI3KC3 complex subunit NRBF2 is required for apoptotic cell clearance to restrict intestinal inflammation.	CCZ1B CCZ1	6.83e-06	3	53	2	32160108
Pubmed	Maternal age-dependent APC/C-mediated decrease in securin causes premature sister chromatid separation in meiosis II.	PTTG1 PTTG2	6.83e-06	3	53	2	28516917
Pubmed	PTTG1 Reprograms Asparagine Metabolism to Promote Hepatocellular Carcinoma Progression.	PTTG1 PTTG2	6.83e-06	3	53	2	37159932
Pubmed	Sex-steroid milieu determines diabetes rescue in pttg-null mice.	PTTG1 PTTG2	6.83e-06	3	53	2	16731783
Pubmed	Pttg1/securin is required for the branching morphogenesis of the mammary gland and suppresses mammary tumorigenesis.	PTTG1 PTTG2	6.83e-06	3	53	2	24395789
Pubmed	Mechanisms for growth factor-induced pituitary tumor transforming gene-1 expression in pituitary folliculostellate TtT/GF cells.	PTTG1 PTTG2	6.83e-06	3	53	2	16959877
Pubmed	Characterization of the murine pituitary tumor transforming gene (PTTG) and its promoter.	PTTG1 PTTG2	6.83e-06	3	53	2	10650958
Pubmed	Regulation of pituitary tumor transforming gene (PTTG) expression and phosphorylation in thyroid cells.	PTTG1 PTTG2	6.83e-06	3	53	2	23867215
Pubmed	The lifespan quantitative trait locus gene Securin controls hematopoietic progenitor cell function.	PTTG1 PTTG2	6.83e-06	3	53	2	31073078
Pubmed	A prometaphase mechanism of securin destruction is essential for meiotic progression in mouse oocytes.	PTTG1 PTTG2	6.83e-06	3	53	2	34262048
Pubmed	Characterization of the pituitary tumor transforming gene 1 knockout mouse retina.	PTTG1 PTTG2	6.83e-06	3	53	2	21203837
Pubmed	Pituitary tumor transforming gene as a novel regulatory factor of liver fibrosis.	PTTG1 PTTG2	6.83e-06	3	53	2	25936962
Pubmed	Mad2 is required for inhibiting securin and cyclin B degradation following spindle depolymerisation in meiosis I mouse oocytes.	PTTG1 PTTG2	6.83e-06	3	53	2	16322543
Pubmed	PTTG1 alleviates acute alcoholic liver injury by inhibiting endoplasmic reticulum stress-induced hepatocyte pyroptosis.	PTTG1 PTTG2	6.83e-06	3	53	2	36737842
Pubmed	Murine pituitary tumor-transforming gene functions as a securin protein in insulin-secreting cells.	PTTG1 PTTG2	6.83e-06	3	53	2	17065388
Pubmed	Discordant proliferation and differentiation in pituitary tumor-transforming gene-null bone marrow stem cells.	PTTG1 PTTG2	6.83e-06	3	53	2	17626243
Pubmed	Pituitary tumor transforming gene: an update.	PTTG1 PTTG2	6.83e-06	3	53	2	15281346
Pubmed	Pituitary senescence: the evolving role of Pttg.	PTTG1 PTTG2	6.83e-06	3	53	2	20153804
Pubmed	Securin and not CDK1/cyclin B1 regulates sister chromatid disjunction during meiosis II in mouse eggs.	PTTG1 PTTG2	6.83e-06	3	53	2	18639540
Pubmed	Pituitary hypoplasia in Pttg-/- mice is protective for Rb+/- pituitary tumorigenesis.	PTTG1 PTTG2	1.36e-05	4	53	2	15919720
Pubmed	Anaphase B precedes anaphase A in the mouse egg.	PTTG1 PTTG2	1.36e-05	4	53	2	22342753
Pubmed	Securin and separase phosphorylation act redundantly to maintain sister chromatid cohesion in mammalian cells.	PTTG1 PTTG2	1.36e-05	4	53	2	16030258
Pubmed	Tumorigenic potential of pituitary tumor transforming gene (PTTG) in vivo investigated using a transgenic mouse model, and effects of cross breeding with p53 (+/-) transgenic mice.	PTTG1 PTTG2	1.36e-05	4	53	2	23164239
Pubmed	Contribution of neuronal calcium sensor 1 (Ncs-1) to anxiolytic-like and social behavior mediated by valproate and Gsk3 inhibition.	ARRB2 NCS1	1.36e-05	4	53	2	32165725
Pubmed	Abnormal megakaryocyte development and platelet function in Nbeal2(-/-) mice.	PTTG1 PTTG2	1.36e-05	4	53	2	23861251
Pubmed	Degradation of securin in mouse and pig oocytes is dependent on ubiquitin-proteasome pathway and is required for proteolysis of the cohesion subunit, Rec8, at the metaphase-to-anaphase transition.	PTTG1 PTTG2	1.36e-05	4	53	2	16720305
Pubmed	The pituitary tumor-transforming gene promotes angiogenesis in a mouse model of follicular thyroid cancer.	PTTG1 PTTG2	1.36e-05	4	53	2	17127711
Pubmed	Spatial learning and long-term memory impairments in RasGrf1 KO, Pttg1 KO, and double KO mice.	PTTG1 PTTG2	1.36e-05	4	53	2	30259712
Pubmed	Tumor suppressor activity of KLF6 mediated by downregulation of the PTTG1 oncogene.	PTTG1 PTTG2	1.36e-05	4	53	2	20116377
Pubmed	Expression of PTTG and prc1 genes during telencephalic neurogenesis.	PTTG1 PTTG2	1.36e-05	4	53	2	10727870
Pubmed	Pituitary tumor-transforming gene 1 regulates the patterning of retinal mosaics.	PTTG1 PTTG2	1.36e-05	4	53	2	24927528
Pubmed	The selective continued linkage of centromeres from mitosis to interphase in the absence of mammalian separase.	PTTG1 PTTG2	1.36e-05	4	53	2	16533944
Pubmed	Separase: a universal trigger for sister chromatid disjunction but not chromosome cycle progression.	PTTG1 PTTG2	1.36e-05	4	53	2	16533945
Pubmed	Aberrant accumulation of PTTG1 induced by a mutated thyroid hormone beta receptor inhibits mitotic progression.	PTTG1 PTTG2	1.36e-05	4	53	2	17039256
Pubmed	Pituitary tumor transforming gene 1 induces tumor necrosis factor-α production from keratinocytes: implication for involvement in the pathophysiology of psoriasis.	PTTG1 PTTG2	1.36e-05	4	53	2	23677169
Pubmed	Transcriptional profiling reveals functional links between RasGrf1 and Pttg1 in pancreatic beta cells.	PTTG1 PTTG2	1.36e-05	4	53	2	25421944
Pubmed	Identification of two evolutionarily conserved genes regulating processing of engulfed apoptotic cells.	CCZ1B CCZ1	1.36e-05	4	53	2	20305638
Pubmed	Preimplantation mouse embryos depend on inhibitory phosphorylation of separase to prevent chromosome missegregation.	PTTG1 PTTG2	1.36e-05	4	53	2	19124608
Pubmed	A single amino acid substitution (Cys249Trp) in Crb1 causes retinal degeneration and deregulates expression of pituitary tumor transforming gene Pttg1.	PTTG1 PTTG2	1.36e-05	4	53	2	17234588
Pubmed	Induction of Dlk1 by PTTG1 inhibits adipocyte differentiation and correlates with malignant transformation.	PTTG1 PTTG2	1.36e-05	4	53	2	19477929
Pubmed	The pituitary tumour-transforming gene 1/delta-like homologue 1 pathway plays a key role in liver fibrogenesis.	PTTG1 PTTG2	1.36e-05	4	53	2	35050550
Pubmed	Homologue disjunction in mouse oocytes requires proteolysis of securin and cyclin B1.	PTTG1 PTTG2	1.36e-05	4	53	2	14593421
Pubmed	The complex of TFII-I, PARP1, and SFPQ proteins regulates the DYX1C1 gene implicated in neuronal migration and dyslexia.	GTF2I DNAAF4	1.36e-05	4	53	2	18445785
Pubmed	Securin regulates entry into M-phase by modulating the stability of cyclin B.	PTTG1 PTTG2	1.36e-05	4	53	2	18364698
Pubmed	Securin is not required for cellular viability, but is required for normal growth of mouse embryonic fibroblasts.	PTTG1 PTTG2	1.36e-05	4	53	2	11516952
Pubmed	Glypican-1 regulates anaphase promoting complex/cyclosome substrates and cell cycle progression in endothelial cells.	PTTG1 PTTG2	1.36e-05	4	53	2	18417614
Pubmed	Senescence mediates pituitary hypoplasia and restrains pituitary tumor growth.	PTTG1 PTTG2	2.27e-05	5	53	2	17975001
Pubmed	p21(Cip1) restrains pituitary tumor growth.	PTTG1 PTTG2	2.27e-05	5	53	2	18981426
Pubmed	The meiosis I-to-meiosis II transition in mouse oocytes requires separase activity.	PTTG1 PTTG2	2.27e-05	5	53	2	14561405
Pubmed	MEIKIN expression and its C-terminal phosphorylation by PLK1 is closely related the metaphase-anaphase transition by affecting cyclin B1 and Securin stabilization in meiotic oocyte.	PTTG1 PTTG2	2.27e-05	5	53	2	39093409
Pubmed	Targeting mitotic exit leads to tumor regression in vivo: Modulation by Cdk1, Mastl, and the PP2A/B55α,δ phosphatase.	PTTG1 PTTG2	2.27e-05	5	53	2	21156286
Pubmed	PTTG-binding factor (PBF) is a novel regulator of the thyroid hormone transporter MCT8.	PTTG1 PTTG2	2.27e-05	5	53	2	22535767
Pubmed	Smurf1 targets Securin for ubiquitin-dependent degradation and regulates the metaphase-to-anaphase transition.	PTTG1 PTTG2	2.27e-05	5	53	2	28658604
Pubmed	The Rae1-Nup98 complex prevents aneuploidy by inhibiting securin degradation.	PTTG1 PTTG2	2.27e-05	5	53	2	16355229
Pubmed	Altered expression of securin (Pttg1) and serpina3n in the auditory system of hearing-impaired Tff3-deficient mice.	PTTG1 PTTG2	2.27e-05	5	53	2	21076990
Pubmed	mTOR promotes pituitary tumor development through activation of PTTG1.	PTTG1 PTTG2	3.40e-05	6	53	2	27524416
Pubmed	Involvement of histone deacetylase 1/2 in adrenocorticotropic hormone synthesis and proliferation of corticotroph tumor AtT-20 cells.	PTTG1 PTTG2	3.40e-05	6	53	2	33181265
Pubmed	Function of COP9 signalosome in regulation of mouse oocytes meiosis by regulating MPF activity and securing degradation.	PTTG1 PTTG2	3.40e-05	6	53	2	21991377
Pubmed	Loss of Cdc20 causes a securin-dependent metaphase arrest in two-cell mouse embryos.	PTTG1 PTTG2	4.76e-05	7	53	2	17325031
Pubmed	The expression of plexins during mouse embryogenesis.	PLXNC1 PLXNB2	6.34e-05	8	53	2	15661641
Pubmed	Mechanisms of pH-gradient driven transport mediated by organic anion polypeptide transporters.	SLCO4C1 SLCO2B1	6.34e-05	8	53	2	19129463
Pubmed	Establishment and Dysfunction of the Blood-Brain Barrier.	SLCO2B1 SLC16A7 SLC38A3	7.00e-05	52	53	3	26590417
Pubmed	FAM105A/OTULINL Is a Pseudodeubiquitinase of the OTU-Class that Localizes to the ER Membrane.	SIRT2 PRDX4 PDZD8 CERS1 PLXNB2 ADCY9	7.73e-05	468	53	6	31056421
Pubmed	Identification of disease-relevant modulators of the SHH pathway in the developing brain.	PTTG1 PTTG2	8.15e-05	9	53	2	34463328
Pubmed	Nuclear pore protein NUP88 activates anaphase-promoting complex to promote aneuploidy.	PTTG1 PTTG2	1.02e-04	10	53	2	26731471
Pubmed	Separase phosphosite mutation leads to genome instability and primordial germ cell depletion during oogenesis.	PTTG1 PTTG2	1.24e-04	11	53	2	21494564
Pubmed	A noncanonical PWI domain in the N-terminal helicase-associated region of the spliceosomal Brr2 protein.	SNRNP200 SF3B2	1.24e-04	11	53	2	25849387
Pubmed	Organic anion transporting polypeptides of the OATP/ SLC21 family: phylogenetic classification as OATP/ SLCO superfamily, new nomenclature and molecular/functional properties.	SLCO4C1 SLCO2B1	1.24e-04	11	53	2	14579113
Pubmed	Transmembrane semaphorin signalling controls laminar stratification in the mammalian retina.	PLXNC1 PLXNB2	1.49e-04	12	53	2	21270798
Pubmed	Specificity and Redundancy of Profilin 1 and 2 Function in Brain Development and Neuronal Structure.	PTTG1 PTTG2	1.76e-04	13	53	2	34571959
Pubmed	Diminished pancreatic beta-cell mass in securin-null mice is caused by beta-cell apoptosis and senescence.	PTTG1 PTTG2	1.76e-04	13	53	2	19213844
Pubmed	Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates.	PLXNC1 PLXNB2	1.76e-04	13	53	2	10520995
Pubmed	TIF1β association with HP1 is essential for post-gastrulation development, but not for Sertoli cell functions during spermatogenesis.	PTTG1 PTTG2	2.36e-04	15	53	2	21163256
Pubmed	Quantitative Proteomics Links the LRRC59 Interactome to mRNA Translation on the ER Membrane.	PRDX4 PDZD8 PLXNB2 SNRNP200 ADCY9	2.66e-04	375	53	5	32788342
Pubmed	Molecular characterization of the ankle-link complex in cochlear hair cells and its role in the hair bundle functioning.	ADGRV1 ADCY9	2.70e-04	16	53	2	17567809
Pubmed	A new role for FBP21 as regulator of Brr2 helicase activity.	SNRNP200 SF3B2	2.70e-04	16	53	2	28838205
Pubmed	Inhibitory phosphorylation of separase is essential for genome stability and viability of murine embryonic germ cells.	PTTG1 PTTG2	2.70e-04	16	53	2	18232736
Pubmed	Plexin-A3 mediates semaphorin signaling and regulates the development of hippocampal axonal projections.	PLXNC1 PLXNB2	3.05e-04	17	53	2	11683995
Pubmed	Semaphorin signaling facilitates cleft formation in the developing salivary gland.	PLXNC1 PLXNB2	3.05e-04	17	53	2	17626059
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CPEB3 WDFY3 PLXNB2	3.24e-04	87	53	3	12465718
Pubmed	Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1.	SIRT2 GTF2I SNRNP200 SF3B2	3.28e-04	215	53	4	35973513
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	WDFY3 ADGRV1 SNRNP200 ADCY9	3.90e-04	225	53	4	12168954
Pubmed	Murine candidate bleomycin induced pulmonary fibrosis susceptibility genes identified by gene expression and sequence analysis of linkage regions.	PTTG1 PTTG2	4.70e-04	21	53	2	15937080
Pubmed	RioK1, a new interactor of protein arginine methyltransferase 5 (PRMT5), competes with pICln for binding and modulates PRMT5 complex composition and substrate specificity.	SIRT2 GTF2I SNRNP200 SF3B2 SDAD1	4.72e-04	425	53	5	21081503
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	NRDE2 SIRT2 ARRB2 GTF2I DSTYK SNRNP200 SF3B2 SDAD1	6.83e-04	1284	53	8	17353931
Pubmed	Smarca4 deficiency induces Pttg1 oncogene upregulation and hyperproliferation of tubular and interstitial cells during kidney development.	PTTG1 PTTG2	7.23e-04	26	53	2	37727504
Pubmed	Notch2 regulates BMP signaling and epithelial morphogenesis in the ciliary body of the mouse eye.	PTTG1 PTTG2	7.80e-04	27	53	2	23676271
Pubmed	Genomic analysis of mouse retinal development.	CCZ1B CCZ1 INTS7 PDZD8 WDFY3 PIK3R5 SLC38A3	8.02e-04	1006	53	7	15226823
Pubmed	The TIP60 Complex Is a Conserved Coactivator of HIF1A.	GTF2I SNRNP200 SF3B2	8.27e-04	120	53	3	27320910
Pubmed	Physiological and pathophysiological characteristics of ataxin-3 isoforms.	GTF2I PRDX4 SNRNP200 SF3B2	8.95e-04	281	53	4	30455355
Pubmed	Identification of ventricular-side-enriched molecules regulated in a stage-dependent manner during cerebral cortical development.	PTTG1 PTTG2	9.64e-04	30	53	2	16420439
Pubmed	KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4.	GTF2I SNRNP200 SF3B2	1.04e-03	130	53	3	35545047
Pubmed	Proteotyping of knockout mouse strains reveals sex- and strain-specific signatures in blood plasma.	PTTG1 PTTG2	1.24e-03	34	53	2	34050187
Pubmed	Joint influence of small-effect genetic variants on human longevity.	NRDE2 SDAD1	1.24e-03	34	53	2	20834067
Pubmed	The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome.	SNRNP200 SF3B2	1.24e-03	34	53	2	15146077
GeneFamily	Plexins	PLXNC1 PLXNB2	1.45e-04	9	37	2	683
GeneFamily	Olfactory receptors, family 8	OR8B2 OR8B3	4.51e-03	49	37	2	155
GeneFamily	Solute carriers	SLCO4C1 SLCO2B1 SLC16A7 SLC38A3	8.39e-03	395	37	4	752
CoexpressionAtlas	DevelopingLowerUrinaryTract_adult_bladder_emap-29457_k-means-cluster#3_top-relative-expression-ranked_1000	DNAAF4 SLCO2B1 CPEB3 CYP4F2 SLC16A7 ADCY9	7.16e-06	208	48	6	gudmap_developingLowerUrinaryTract_adult_bladder_1000_k3
CoexpressionAtlas	Stem Cells, SC.MDP.BM, Sca1- Flt3+ MCSFR+ cKithi, Bone marrow, avg-3	G6PC3 PRDX4 TMEM97 LBP PLXNB2 SLC16A7 KMO	3.12e-05	402	48	7	GSM791105_500
CoexpressionAtlas	Mesoderm Day 5_vs_Mesoderm Day 15-Confounder_removed-fold2.0_adjp0.05	CCZ1B PTTG1 GTF2I G6PC3 CCZ1 DNAAF4 MTMR2 SLAIN1 ZDHHC13 PIK3R5 NCS1	1.02e-04	1276	48	11	PCBC_ratio_MESO-5_vs_MESO-15_cfr-2X-p05
CoexpressionAtlas	DevelopingLowerUrinaryTract_P1_ureter_emap-30363_k-means-cluster#1_top-relative-expression-ranked_1000	SLCO2B1 CPEB3 CYP4F2 SLC16A7	1.61e-04	121	48	4	gudmap_developingLowerUrinaryTract_P1_ureter_1000_k1
CoexpressionAtlas	DevelopingLowerUrinaryTract_P1_ureter_emap-30363_k-means-cluster#4_top-relative-expression-ranked_500	SLCO2B1 CYP4F2 SLC16A7	1.64e-04	47	48	3	gudmap_developingLowerUrinaryTract_P1_ureter_500_k4
ToppCell	COVID-19-lung-Macrophage_CD163hi_MERTKhi\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ARRB2 PLXNC1 SLCO2B1 PIK3R5 KMO	3.61e-06	196	53	5	7026c1fc33425e5476063d17c79e4b79356a9e01
ToppCell	COVID-19-Myeloid-Transitioning_MDM\|COVID-19 / group, cell type (main and fine annotations)	ARRB2 PLXNC1 SLCO2B1 PIK3R5 KMO	3.61e-06	196	53	5	4929cfed1f150c1fde4d79cb49895c2ea467a18f
ToppCell	droplet-Marrow-BM-30m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLCO4C1 DSTYK ADGRV1 ADCY9	4.34e-05	164	53	4	b77995958c938e10a526118f75d78cee72e0b207
ToppCell	droplet-Spleen-SPLEEN-30m-Myeloid-granulocyte\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARRB2 SLCO4C1 LBP MOCOS	4.76e-05	168	53	4	c0ff30e2c47005514131a0866cf10a1c228128fc
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic-Monocyte-derived_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ARRB2 PLXNC1 SLCO2B1 PIK3R5	5.22e-05	172	53	4	72fbfa890995e47048b47199c170cc7dcd7661f8
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ARRB2 PLXNC1 SLCO2B1 PIK3R5	5.22e-05	172	53	4	2ca6f0d1181aabe0d0e3e8f2e193f08dbda42dea
ToppCell	LPS-IL1RA-Myeloid-Monocytes,_Macrophages-Monocytes-Macrophages\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ARRB2 PLXNC1 PIK3R5 KMO	6.23e-05	180	53	4	97241f62ee133dcb0d4855ffda5dd1349de9f7b2
ToppCell	LPS-IL1RA-Myeloid-Monocytes,_Macrophages\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ARRB2 PLXNC1 PIK3R5 KMO	6.23e-05	180	53	4	41896546cd1cc458e08c0d4e19aa4860e5d4fcd6
ToppCell	cellseq2-Immune-Immune_Myeloid-Myeloid_Dendritic-cDC2\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ARRB2 PLXNC1 SLCO2B1 LGALS12	6.64e-05	183	53	4	9840706f972387241bf1d4ba8af25efc3214a91b
ToppCell	cellseq2-Immune-Immune_Myeloid-Myeloid_Dendritic\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ARRB2 PLXNC1 SLCO2B1 LGALS12	6.64e-05	183	53	4	409cb52cf4c967e52bf75a6680bcbe87f638c75d
ToppCell	B_cells-ABCs\|B_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	ARRB2 SLCO4C1 PLXNC1 PIK3R5	6.64e-05	183	53	4	bf9c6fe3ce4e44e4056027257eab8448c39c4fb8
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Monocytic-Monocyte-derived_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ARRB2 PLXNC1 SLCO2B1 PIK3R5	7.37e-05	188	53	4	0d7296ad26e97ad91c6927a6cfe4e6e70a74c5a6
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Monocytic\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ARRB2 PLXNC1 SLCO2B1 PIK3R5	7.68e-05	190	53	4	7c402aa47f1bd7decacc366c1ed1a37e39b95c73
ToppCell	droplet-Marrow-BM-1m-Lymphocytic-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GTF2I G6PC3 TMEM97 KMO	7.83e-05	191	53	4	4187f31ec399b4c7c3608e94e3c32b7a54b1c3d4
ToppCell	Control-Myeloid\|Control / group, cell type (main and fine annotations)	ARRB2 SLCO2B1 PIK3R5 KMO	7.83e-05	191	53	4	9c4acc5f3c2f9c0c5520863bb22f391774372347
ToppCell	Severe-Treg\|World / Disease group and Cell class	DNAAF4 PRDX4 LGALS12 ADGRV1	7.83e-05	191	53	4	0a80b8c317e8da4d4722cfd13cdabc32b58021eb
ToppCell	droplet-Marrow-BM-1m-Lymphocytic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GTF2I G6PC3 TMEM97 KMO	7.83e-05	191	53	4	8e8bc200524a44ebe132f823ab7c15dac65d4952
ToppCell	COVID-19-lung-Macrophage_PPARGhi_CD5Lhi\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ARRB2 SLCO2B1 PIK3R5 KMO	7.99e-05	192	53	4	bcfb9c005166bc0b4f8ee2dfc0c1540e8bf0e1ff
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Immune\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ARRB2 PLXNC1 SLCO2B1 PIK3R5	8.32e-05	194	53	4	96f16bcd393a0d3f8df479b172b5360ae5a1e663
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ARRB2 PLXNC1 SLCO2B1 PIK3R5	8.49e-05	195	53	4	91a3c439f10c03c5d51d904f512b6a08040edc76
ToppCell	COVID-19-Myeloid-Monocyte-derived_macrophages\|COVID-19 / group, cell type (main and fine annotations)	ARRB2 SLCO2B1 PIK3R5 KMO	8.49e-05	195	53	4	c172c5599379c29123340621a36bfb1fc90c2115
ToppCell	Macrophages-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	ARRB2 PLXNC1 SLCO2B1 PIK3R5	8.49e-05	195	53	4	eb104f3bb08ab9eca31273c0523a5c90de1f30a9
ToppCell	COVID-19-lung-Macrophage_CD163hi_MERTKhi\|lung / Disease (COVID-19 only), tissue and cell type	ARRB2 SLCO2B1 PIK3R5 KMO	8.49e-05	195	53	4	148fff8c3c9ba45ec36e98dff1be57e3f8294506
ToppCell	COVID-19-lung-Macrophage_metabolically_active\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ARRB2 LINGO1 SLCO2B1 PIK3R5	8.65e-05	196	53	4	1b7928f4eee94d4bb6ea410bab68a471dba12979
ToppCell	COVID-19-lung-Macrophage_metabolically_active\|lung / Disease (COVID-19 only), tissue and cell type	ARRB2 SLCO2B1 PIK3R5 KMO	8.65e-05	196	53	4	a753d76d764c181eecb0e17a794a2e7d0ff70136
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ARRB2 PLXNC1 SLCO2B1 PIK3R5	8.83e-05	197	53	4	8af4a1e35ce9fb4ea3d26ab619599efb7eac43a5
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ARRB2 PLXNC1 SLCO2B1 PIK3R5	8.83e-05	197	53	4	6ca6e17b7cc5f7ea8d4b6ca1ff670969bee65a45
ToppCell	COVID-19-lung-Macrophage_LDB2hi_OSMRhi_YAP1hi\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ARRB2 PLXNC1 SLCO2B1 PIK3R5	8.83e-05	197	53	4	e42910a653a1b5bd90c090e9665a84871ed2873f
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macrophage_intermediate\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ARRB2 SLCO2B1 LGALS12 PIK3R5	8.83e-05	197	53	4	e2983ae16c72371fbf0e5c123de9f4d900724e5e
ToppCell	COVID-19-lung-Macrophage_LDB2hi_OSMRhi_YAP1hi\|lung / Disease (COVID-19 only), tissue and cell type	ARRB2 PLXNC1 SLCO2B1 PIK3R5	8.83e-05	197	53	4	3896729740d151f0eb845f1961c7b969bfbdd28d
ToppCell	Parenchymal-NucSeq-Immune_Myeloid-Macrophage_other-Macro_CHIT1\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PLXNC1 SLCO2B1 PIK3R5 KMO	9.00e-05	198	53	4	6a4161680b46b2c12353a693c403b5a4bb3da03f
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	LINGO1 WDFY3 ADGRV1 ADCY9	9.00e-05	198	53	4	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ARRB2 PLXNC1 SLCO2B1 PIK3R5	9.00e-05	198	53	4	96883ad8e189a46ed5b7eaafc0543e53682d26ed
ToppCell	COVID-19-Myeloid\|COVID-19 / group, cell type (main and fine annotations)	ARRB2 SLCO2B1 PIK3R5 KMO	9.00e-05	198	53	4	33f0a919188a67d2a876b52c61a1cec2c9747969
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macro_CHIT1\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PLXNC1 SLCO2B1 PIK3R5 KMO	9.00e-05	198	53	4	0b41b3d6c2db795320e8b65d40d85fb8b618cc34
ToppCell	Tracheal-10x5prime-Immune_Myeloid-Macrophage_other-Macro_CHIT1\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	PLXNC1 SLCO2B1 PIK3R5 KMO	9.00e-05	198	53	4	9430ce7016b1a4724de036aab3e3e4082d24e436
ToppCell	Fetal_29-31_weeks-Immune\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ARRB2 SLCO2B1 PIK3R5 PARP15	9.00e-05	198	53	4	5dff131356b8c22743bd27b2b21f86ee6e4a0a0d
ToppCell	COVID-19-kidney-Macrophages\|kidney / Disease (COVID-19 only), tissue and cell type	ARRB2 PLXNC1 SLCO2B1 PIK3R5	9.00e-05	198	53	4	161324541fe5da5cbb58142ea94fefd39b7dfb04
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ARRB2 PLXNC1 SLCO2B1 PIK3R5	9.18e-05	199	53	4	04adf46975aa4194ea40c7480f8a517def5d929c
ToppCell	COPD-Myeloid-Macrophage\|Myeloid / Disease state, Lineage and Cell class	NRDE2 SLCO2B1 PIK3R5 NCS1	9.18e-05	199	53	4	1cf1b2d6debf9e3389f1829dcaa2857e9533a080
ToppCell	Tracheal-10x5prime-Immune_Myeloid-Macrophage_other-Macro_CCL\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ARRB2 PLXNC1 SLCO2B1 PIK3R5	9.18e-05	199	53	4	c72279fa3ca2ebc42a1446507673df154b8033c7
ToppCell	Tracheal-NucSeq-Immune_Myeloid-Macrophage_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ARRB2 SLCO2B1 PIK3R5 KMO	9.18e-05	199	53	4	98c0d57c247d39bc771d81f4387f8dd01222628e
ToppCell	Tracheal-NucSeq-Immune_Myeloid-Macrophage_alveolar-Macro_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ARRB2 SLCO2B1 PIK3R5 KMO	9.18e-05	199	53	4	b818d46a39c8782188d82dc8931b8eec9d549dd1
ToppCell	Tracheal-NucSeq-Immune_Myeloid-Macrophage_other-Macro_AW_CX3CR1\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ARRB2 PLXNC1 SLCO2B1 PIK3R5	9.18e-05	199	53	4	744b63fba33b176ab7dde11646ccb313665505f7
ToppCell	Parenchymal-NucSeq-Immune_Myeloid\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ARRB2 SLCO2B1 PIK3R5 KMO	9.18e-05	199	53	4	7ee2805fd9143eba11bf6832267b62189683608b
ToppCell	cellseq-Immune-Immune_Myeloid-IM\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ARRB2 PLXNC1 SLCO2B1 PIK3R5	9.18e-05	199	53	4	b3267d5a7ae0461f5e9e6a3ab6783317a8c42506
ToppCell	Tracheal-NucSeq-Immune_Myeloid-Macrophage_other-Macro_CHIT1\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ARRB2 PLXNC1 SLCO2B1 PIK3R5	9.18e-05	199	53	4	6ce7612ee2ae211eb0f73391e96089ad5431c537
ToppCell	Tracheal-NucSeq-Immune_Myeloid-Macrophage_other-Macrophage_intermediate\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ARRB2 SLCO2B1 PIK3R5 KMO	9.18e-05	199	53	4	54167894a16e975d0541cbe3e515bcfa183044f6
ToppCell	cellseq-Immune-Immune_Myeloid-IM-IM\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ARRB2 PLXNC1 SLCO2B1 PIK3R5	9.18e-05	199	53	4	01dacee8bb392639d475be3cb27ba3eeff1e57f1
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Macrophage_other\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ARRB2 SLCO2B1 PIK3R5 KMO	9.36e-05	200	53	4	78d75d381cb2b9a4c9eb7c32a07b014eaee39195
ToppCell	Tracheal-10x5prime-Immune_Myeloid\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ARRB2 SLCO2B1 PIK3R5 KMO	9.36e-05	200	53	4	fc6aebc20ecaa67606154540a691242dc0aea867
ToppCell	Bronchial-NucSeq-Immune_Myeloid\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ARRB2 SLCO2B1 PIK3R5 KMO	9.36e-05	200	53	4	2f5b71e55c2de0e77fdae6667eb57f333acc6cd1
ToppCell	Tracheal-NucSeq-Immune_Myeloid-Monocytic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ARRB2 PLXNC1 SLCO2B1 PIK3R5	9.36e-05	200	53	4	48ce43a27e78b2883e588e1a63fa5352c2deeeb7
ToppCell	Entopeduncular-Macroglia-OLIGODENDROCYTE\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	SPEF2 SLAIN1 ADGRV1	4.97e-04	130	53	3	0a6b87635e650df431a88f2e6396abead84d901d
ToppCell	droplet-Pancreas-Exocrine-21m-Epithelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRDX4 TMEM97 SLC38A3	5.31e-04	133	53	3	91e4556658e49f92946d48b194df64c5fc5758fe
ToppCell	COVID-19_Mild-Myeloid_G-Neutrophil\|COVID-19_Mild / Disease group, lineage and cell class	PLXNC1 CYP4F2 ERICH6	5.55e-04	135	53	3	e9eb2bebb6d19c439c83f46c12ca0d676db69de8
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligodendroglioma-5\|TCGA-Brain / Sample_Type by Project: Shred V9	RNF103 SLAIN1 ADGRV1	5.79e-04	137	53	3	a7c76201b8901b2ef7ebbb4dfe0cec0dc4534ef5
ToppCell	droplet-Pancreas-Exocrine-21m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRDX4 TMEM97 SLC38A3	7.97e-04	153	53	3	39ac25c48e73538f1c10f37bea386e0e88d3e8d0
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW19\|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.	DSTYK SPEF2 PTTG2	8.28e-04	155	53	3	9d53caee196b5c2bbc90c4f54f693b64d4086065
ToppCell	facs-Liver-Hepatocytes\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLCO2B1 SLC16A7 SLC38A3	8.43e-04	156	53	3	e2cda3ad4e5f44a80133864c5a38b766afb952ce
ToppCell	droplet-Liver-Hepatocytes-24m-Lymphocytic-NK/T\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DNAAF4 SLAIN1 PADI1	8.59e-04	157	53	3	16581e2399a211633f870dce326c75ff4b6a5fe6
ToppCell	droplet-Liver-Hepatocytes-24m-Lymphocytic-NK_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DNAAF4 SLAIN1 PADI1	8.59e-04	157	53	3	cbb08d5c151f0622123276926a2a15bb7d271e90
ToppCell	Control-Epithelial_airway\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DNAAF4 ADGRV1 PADI1	8.75e-04	158	53	3	35aee1c3b92169e73569331022833cb44ab7e7e8
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-plasmacytoid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZDHHC13 KMO PADI1	9.24e-04	161	53	3	ed93cb6c133855a5c244821e1a260aae8ab4df9a
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-Plasmacytoid_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZDHHC13 KMO PADI1	9.24e-04	161	53	3	0089d7bb305c592392791862a3341fc92af8f3e2
ToppCell	VE-CD8-CD4_Treg\|VE / Condition, Cell_class and T cell subcluster	PTTG1 ADGRV1 SDAD1	9.24e-04	161	53	3	a114f4f75859d9ef900e5146686438d051241429
ToppCell	PCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_macrophage-im_macrophage_(16)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	SLCO2B1 PIK3R5 PARP15	9.41e-04	162	53	3	2b47fd256490d0c2d9ad5950aa26410aeb6ec995
ToppCell	droplet-Pancreas-Exocrine-21m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRDX4 TMEM97 SLC38A3	9.41e-04	162	53	3	922ecea81063095b8dd9ac9f9792bf551edbb848
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_low-phase\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	G6PC3 KMO ERICH6	9.57e-04	163	53	3	2d6fd2562d78be9f83fa35d811eb7e27eb8cc5d1
ToppCell	B_cells-ABCs\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	SLCO4C1 KMO PARP15	9.74e-04	164	53	3	f45013706a917f0f0d69c23f288128f252cd60c7
ToppCell	facs-Heart-LV-3m-Mesenchymal-atrial_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLCO4C1 PIK3R5 ERICH6	9.92e-04	165	53	3	af59a095ecc6758abc13d763c00e44447c488167
ToppCell	droplet-Pancreas-Exocrine-21m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRDX4 TMEM97 SLC38A3	9.92e-04	165	53	3	c17e00ec9dbe30fcded65a461231dbb13665ddac
ToppCell	facs-Heart-LV-3m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLCO4C1 PIK3R5 ERICH6	9.92e-04	165	53	3	84eca6a0f5e996b6955ae79fa102af239098fe8f
ToppCell	droplet-Spleen-nan-24m-Myeloid-granulocyte\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARRB2 LBP MOCOS	9.92e-04	165	53	3	3cdb921f5b9facf04f81995d5641ac14ef3dbb6f
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRDX4 PCDHB2 ERICH6	1.03e-03	167	53	3	b4ef07117d14da3d5fbced949e4dfcb01c392295
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRDX4 PCDHB2 ERICH6	1.03e-03	167	53	3	94fc7df7ca55cd722a8dbd153201a29891217473
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRDX4 PCDHB2 ERICH6	1.03e-03	167	53	3	eff3723fe60755272eca237459165e436e919ece
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SLCO2B1 PIK3R5 KMO	1.04e-03	168	53	3	26fce414439ccd204e3acb41f2b4f75072df5a26
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SLCO2B1 PIK3R5 KMO	1.04e-03	168	53	3	61a5435b27b01ff1a509ea463a6af220c5d2c9b3
ToppCell	PCW_07-8.5-Immune_Lymphocytic-Immune_Lymphocytic_B-im_B_cell_(15)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	LGALS12 PIK3R5 PARP15	1.04e-03	168	53	3	2ec53f91de3bff8a106430a78b81ee6870f0c55e
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ARRB2 SLCO2B1 PIK3R5	1.06e-03	169	53	3	b2fdf9f842dc7c181bc951a8a6932c916ed835ef
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic-Monocyte-derived_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ARRB2 SLCO2B1 PIK3R5	1.06e-03	169	53	3	2322f03a115c662f808ebfc892192b7d38d48181
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid-Macrophage-macrophage,_alveolar-Macro_c3-EREG\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	PLXNC1 PIK3R5 KMO	1.08e-03	170	53	3	9ac1ef57f14418a5dd2aa16861c3df698c28f5ed
ToppCell	droplet-Lung-1m-Hematologic-myeloid-interstitial_macrophage\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ARRB2 SLCO2B1 NCS1	1.08e-03	170	53	3	f664c7559e383b37845c123e41a3be316d869ba0
ToppCell	droplet-Lung-1m-Hematologic-myeloid-interstitial_macrophage-interstitial_macrophage_l12\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ARRB2 SLCO2B1 NCS1	1.08e-03	170	53	3	0272eb1487c2545d4aa06f5d1cd77f823e1441e9
ToppCell	droplet-Lung-nan-18m-Myeloid-Interstitial_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARRB2 SLCO2B1 ZDHHC13	1.10e-03	171	53	3	7ca404539344e14dcd90c746c9122f713a7db78b
ToppCell	droplet-Lung-nan-18m-Myeloid-lung_macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARRB2 SLCO2B1 ZDHHC13	1.10e-03	171	53	3	ab113c8e773b0af47a87aed50e96be3ba71c3c82
ToppCell	facs-Marrow-T_cells-18m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLCO4C1 LBP MOCOS	1.10e-03	171	53	3	95e87987a2332fa646849fb0de785f1e0b8a07dd
ToppCell	facs-Marrow-T_cells-18m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLCO4C1 LBP MOCOS	1.10e-03	171	53	3	36657e277aad75c4f157c1726c48e09b5836cf37
ToppCell	3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PIGV ZDHHC13 MOCOS	1.12e-03	172	53	3	5401ac7739f95fb8681cfb4747ab6e447a3c2ae8
ToppCell	3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PIGV ZDHHC13 MOCOS	1.12e-03	172	53	3	b3da7f488d191214d7bb74fbac189fe8c29ee6cd
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SLCO2B1 LGALS12 PARP15	1.12e-03	172	53	3	3a37569a5902f3c65ff8d3912421309a8c82ee9b
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic-Mast_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SLCO2B1 LGALS12 PARP15	1.12e-03	172	53	3	cc9d9dae290f11f8c348c78228af4e49469dc93b
ToppCell	MS-CD8-proli_CD4\|MS / Condition, Cell_class and T cell subcluster	SLAIN1 PIK3R5 ADCY9	1.12e-03	172	53	3	0b6dd257110b3f17fa71ab18a165b091a9d5ae9a
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CPEB3 ADGRV1 SLC16A7	1.12e-03	172	53	3	1565f38266891c3acf49778838de134c5dee5460
ToppCell	3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PIGV ZDHHC13 MOCOS	1.12e-03	172	53	3	74dd4a7acb2cf857fed20219e4d7dc1adfbaa398
ToppCell	390C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	SLCO2B1 PCDHB2 WDFY3	1.14e-03	173	53	3	1f725ff16e28636b20ef26f3fa9be8b47c89378d
ToppCell	droplet-Lung-LUNG-1m-Myeloid-lung_macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARRB2 SLCO2B1 NCS1	1.14e-03	173	53	3	69b404e92aad3e6dff67e75466f073f20a71f13f
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Granulocytic-Neutrophil\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ARRB2 PLXNC1 LGALS12	1.14e-03	173	53	3	dfa56753319c92ae5b337793c4d6d5f70afce546
ToppCell	droplet-Lung-LUNG-1m-Myeloid-Interstitial_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARRB2 SLCO2B1 NCS1	1.14e-03	173	53	3	26bba58f9fb215d1d155504906cd77e8774f6936
Drug	Troleandomycin [2751-09-9]; Up 200; 5uM; HL60; HG-U133A	RNF103 DERL2 MTMR2 PIGV PLXNB2 PADI1	5.85e-06	198	52	6	1965_UP
Disease	cutaneous melanoma, hair color	DSTYK ADGRV1 PLXNB2	1.43e-04	62	48	3	EFO_0000389, EFO_0003924
Disease	Sjogren's Syndrome	PTTG1 GTF2I	2.00e-04	13	48	2	C1527336
Disease	Sicca Syndrome	PTTG1 GTF2I	2.00e-04	13	48	2	C0086981
Disease	Hermansky-Pudlak syndrome (implicated_via_orthology)	CCZ1B CCZ1	2.33e-04	14	48	2	DOID:3753 (implicated_via_orthology)
Disease	basophil percentage of leukocytes	DSTYK SPEF2 LGALS12 LBP	6.57e-04	243	48	4	EFO_0007992
Disease	conotruncal heart malformations	PLXNC1 ADGRV1 SLC38A3	8.56e-04	114	48	3	MONDO_0016581
Disease	cytokine measurement	SLCO4C1 SLCO2B1 SPEF2 ZDHHC13 NCS1	8.97e-04	461	48	5	EFO_0004873
Disease	cutaneous melanoma	DSTYK ADGRV1 PLXNB2	1.02e-03	121	48	3	EFO_0000389
Disease	Polynesian Bronchiectasis	DNAAF4 SPEF2	1.49e-03	35	48	2	C4317124
Disease	Ciliary Dyskinesia, Primary, 1, With Or Without Situs Inversus	DNAAF4 SPEF2	1.49e-03	35	48	2	C4551906
Disease	Kartagener Syndrome	DNAAF4 SPEF2	1.49e-03	35	48	2	C0022521
Disease	hair color	DSTYK ADGRV1 PIGV PLXNB2	1.64e-03	311	48	4	EFO_0003924
Disease	Primary Ciliary Dyskinesia	DNAAF4 SPEF2	2.67e-03	47	48	2	C4551720

Protein segments in the cluster

Peptide	Gene	Start	Entry
PFVSFKPVFLALNRY	ERICH6	531	Q7L0X2
AFPDKIPEFNEFYFL	ADGRV1	1191	Q8WXG9
FRKDLFIATYQAFPP	ARRB2	76	P32121
LFFLKNFYAEAFFPD	PADI1	571	Q9ULC6
LFQKYPFPILINSAF	INTS7	51	Q9NVH2
LPFFLKPSVENFYTL	PCDHB2	391	Q9Y5E7
SPKLFVVFFDNQAYP	PARP15	656	Q460N3
FYPKFNDKLAEGFPL	LBP	436	P18428
IYKQFFPFGDPTKFA	NCS1	51	P62166
FLGDPKILFLFYFPA	G6PC3	31	Q9BUM1
PPAVKYFFDFLDEQA	PLXNB2	1651	O15031
PNSRAPFAIKYFFDF	PLXNC1	1376	O60486
PFAIKYFFDFLDAQA	PLXNC1	1381	O60486
SAPFLFYPQRFFEVL	LGALS12	276	Q96DT0
PFTNFPIDKVLSVFY	OR4K3	261	Q96R72
RFKPFFPYQTLQGFE	PDZD8	291	Q8NEN9
LYDEKPLTFFNPLFS	NRDE2	671	Q9H7Z3
DNPFFDLSVYFLPVA	DUSP13	106	Q9UII6
FFAPIIFLAPYAKDQ	SLC16A7	261	O60669
KYAFPVSNNLPLFAF	MTMR2	181	Q13614
EFKDFPDVLLPNYFT	LINGO1	406	Q96FE5
DFVPISFYKIFGFPT	MOCOS	256	Q96EN8
PEFQQPLFFLFLVVY	OR8B3	21	Q8NGG8
YFSFPVFFFKVPKLG	DSTYK	271	Q6XUX3
FFQKYFPDAIPLIGE	KMO	256	O15229
FPPKGYAFLLFQEES	CPEB3	481	Q8NE35
QEKQFPPALLSFFIY	CCZ1	16	P86791
QEKQFPPALLSFFIY	CCZ1B	16	P86790
YFFKPPINQFSLNFL	ADCY9	741	O60503
SLRTVPDIPFYFFFN	CERS1	271	P27544
PDIPFYFFFNALLLL	CERS1	276	P27544
AIAPKDKFFYSFLEP	CYP4F2	116	P78329
TENYLKVNFPPFLFE	DNAAF4	36	Q8WXU2
KVNFPPFLFEAFLYA	DNAAF4	41	Q8WXU2
ITPFQLYFNPELIFK	DERL2	36	Q9GZP9
KVPFALFESFPEDFY	GTF2I	756	P78347
KIYLFANLDQPPAFF	RNF103	236	O00237
KFFPFNPLDFESFDL	PTTG1	116	O95997
PEFRQPLFFLFLVIY	OR8B2	21	Q96RD0
FFFRLFADYEKDPPQ	SPEF2	1611	Q9C093
QFPFYDSIPQELFRK	STK40	271	Q8N2I9
PFLIFIFPAIFYFRI	SLC38A3	441	Q99624
LVFFFYPLDFTFVCP	PRDX4	111	Q13162
PEAPFVYFKPAAGFF	SLAIN1	121	Q8ND83
FFALAKELYPGQFKP	SIRT2	131	Q8IXJ6
YPEIEKFFPFNLLDF	PTTG2	111	Q9NZH5
FLFNFYPFLQRFLQP	SDAD1	331	Q9NVU7
YEHNFAFFPGFPLAL	PIGV	81	Q9NUD9
PEIYEPNFIFFKRIF	SF3B2	376	Q13435
LIPEFFYLPEFLFNS	WDFY3	2846	Q8IZQ1
LFFPDLAGAPFYFSF	ZDHHC13	366	Q8IUH4
PLLTRFFKLQFFYVP	PIK3R5	546	Q8WYR1
AVALAAIPYFFFPKE	SLCO2B1	286	O94956
FFNGFAIFLYKPPPS	SLCO4C1	681	Q6ZQN7
FQLPFFPIATYAFLK	TMEM97	76	Q5BJF2
AFESLYQDKFPFFNP	SNRNP200	1316	O75643
KIPYFEPLTLFNLFA	TAS2R8	176	Q9NYW2