Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	calmodulin-dependent protein phosphatase activity	PPP3CA PPP3CB PPP3CC	2.45e-05	5	272	3	GO:0033192
GeneOntologyMolecularFunction	protein kinase activity	SMG1 TRIO INSRR IRAK2 PHKA1 PTK2B PHKG2 MYLK3 NRK ALK MAP3K19 CAMK2B AAK1 GRK1 CASK PIKFYVE TNNI3K IGF1R IKBKE MTOR ROS1 SBK2	2.72e-05	600	272	22	GO:0004672
GeneOntologyMolecularFunction	calcium/calmodulin-dependent protein kinase activity	PHKA1 PTK2B PHKG2 MYLK3 CAMK2B	2.85e-05	27	272	5	GO:0004683
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	DAB2IP TRIO DOCK11 IQSEC2 ARHGAP11A ANKRD27 GPSM2 SIPA1L2 ARHGAP11B CCZ1B ARHGEF28 RHOD DOCK9 ARFGEF3 ARAP3 RASAL3 CCZ1 DOCK7 RAPGEFL1	7.27e-05	507	272	19	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	DAB2IP TRIO DOCK11 IQSEC2 ARHGAP11A ANKRD27 GPSM2 SIPA1L2 ARHGAP11B CCZ1B ARHGEF28 RHOD DOCK9 ARFGEF3 ARAP3 RASAL3 CCZ1 DOCK7 RAPGEFL1	7.27e-05	507	272	19	GO:0030695
GeneOntologyMolecularFunction	calmodulin binding	MYO1G RYR2 PHKA1 PHKG2 ASPM CAMK2B UBR4 CASK PPP3CA PPP3CB PPP3CC KCNH5	7.91e-05	230	272	12	GO:0005516
GeneOntologyMolecularFunction	guanyl-nucleotide exchange factor activity	TRIO DOCK11 IQSEC2 ANKRD27 CCZ1B ARHGEF28 RHOD DOCK9 ARFGEF3 CCZ1 DOCK7 RAPGEFL1	8.24e-05	231	272	12	GO:0005085
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	SMG1 TRIO INSRR IRAK2 PHKA1 PTK2B PHKG2 SGMS1 MYLK3 CHPT1 NRK ALK MAP3K19 CAMK2B AAK1 PARP14 GRK1 CASK PIKFYVE TNNI3K IGF1R IKBKE MTOR TNKS ROS1 POLG2 G6PC1 SBK2	8.75e-05	938	272	28	GO:0016772
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	SMG1 TRIO INSRR IRAK2 PHKA1 PTK2B PHKG2 MYLK3 NRK ALK MAP3K19 CAMK2B AAK1 GRK1 CASK PIKFYVE TNNI3K IGF1R IKBKE MTOR ROS1 G6PC1 SBK2	1.15e-04	709	272	23	GO:0016773
GeneOntologyMolecularFunction	calcium-dependent protein serine/threonine phosphatase activity	PPP3CA PPP3CB PPP3CC	1.33e-04	8	272	3	GO:0004723
GeneOntologyMolecularFunction	protein serine/threonine kinase activity	SMG1 TRIO PHKA1 PTK2B PHKG2 MYLK3 NRK MAP3K19 CAMK2B AAK1 GRK1 CASK PIKFYVE TNNI3K IKBKE MTOR SBK2	1.42e-04	446	272	17	GO:0004674
GeneOntologyMolecularFunction	dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity	ALG10B ALG10	1.85e-04	2	272	2	GO:0106073
GeneOntologyMolecularFunction	cysteine-tRNA ligase activity	CARS2 CARS1	1.85e-04	2	272	2	GO:0004817
GeneOntologyMolecularFunction	semaphorin receptor binding	SEMA3A SEMA6D SEMA5B SEMA3E	2.43e-04	23	272	4	GO:0030215
GeneOntologyMolecularFunction	kinase activity	SMG1 TRIO INSRR IRAK2 PHKA1 PTK2B PHKG2 SGMS1 MYLK3 NRK ALK MAP3K19 CAMK2B AAK1 GRK1 CASK PIKFYVE TNNI3K IGF1R IKBKE MTOR ROS1 SBK2	3.38e-04	764	272	23	GO:0016301
GeneOntologyMolecularFunction	insulin receptor activity	INSRR IGF1R	5.50e-04	3	272	2	GO:0005009
GeneOntologyMolecularFunction	chemorepellent activity	SEMA3A SEMA6D SEMA5B SEMA3E	6.12e-04	29	272	4	GO:0045499
GeneOntologyMolecularFunction	phosphorylase kinase activity	PHKA1 PHKG2	1.09e-03	4	272	2	GO:0004689
GeneOntologyBiologicalProcess	glycogen catabolic process	INS PHKA1 PHKG2 ATG2B G6PC1 INS-IGF2	5.38e-06	35	268	6	GO:0005980
GeneOntologyBiologicalProcess	glucan catabolic process	INS PHKA1 PHKG2 ATG2B G6PC1 INS-IGF2	6.39e-06	36	268	6	GO:0009251
GeneOntologyBiologicalProcess	polysaccharide catabolic process	INS PHKA1 PHKG2 ATG2B G6PC1 INS-IGF2	8.86e-06	38	268	6	GO:0000272
GeneOntologyBiologicalProcess	regulation of glycogen catabolic process	INS PHKA1 PHKG2 INS-IGF2	2.52e-05	14	268	4	GO:0005981
GeneOntologyBiologicalProcess	negative regulation of DNA metabolic process	ERCC1 RTEL1 ANKLE1 SHLD1 MSH3 ANKRD1 TNKS SLFN11 CERS1 HCRT	3.65e-05	155	268	10	GO:0051053
GeneOntologyBiologicalProcess	protein autophosphorylation	SMG1 INS INSRR IRAK2 PTK2B ALK CAMK2B GRK1 PIKFYVE IGF1R MTOR ROS1	4.64e-05	228	268	12	GO:0046777
GeneOntologyBiologicalProcess	regulation of carbohydrate catabolic process	INS PHKA1 PHKG2 HSD11B1 SLC25A12 MTOR INS-IGF2	9.58e-05	82	268	7	GO:0043470
GeneOntologyBiologicalProcess	energy reserve metabolic process	INS PHKA1 PHKG2 KL ATG2B MTOR G6PC1 INS-IGF2	1.23e-04	114	268	8	GO:0006112
GeneOntologyBiologicalProcess	cell morphogenesis involved in neuron differentiation	TRIO ANKRD27 SEMA3A SEMA6D SEMA5B UBE3A ARHGEF28 HDAC6 FEZF2 CAMK2B SMURF1 SPG11 LHX3 LMO4 GRK1 CASK IGF1R PPP3CA PPP3CB CELSR3 DOCK7 RERE SEMA3E	1.26e-04	748	268	23	GO:0048667
GeneOntologyBiologicalProcess	neuron projection morphogenesis	DAB2IP TRIO ANKRD27 SEMA3A SEMA6D SEMA5B UBE3A ARHGEF28 HDAC6 FEZF2 CAMK2B SMURF1 SPG11 LHX3 LMO4 CASK LIFR IGF1R PPP3CA PPP3CB CELSR3 DOCK7 RERE SEMA3E	1.36e-04	802	268	24	GO:0048812
GeneOntologyBiologicalProcess	positive regulation of granulosa cell proliferation	MTA3 MTOR	1.68e-04	2	268	2	GO:1904197
GeneOntologyBiologicalProcess	regulation of granulosa cell proliferation	MTA3 MTOR	1.68e-04	2	268	2	GO:1904195
GeneOntologyBiologicalProcess	cysteinyl-tRNA aminoacylation	CARS2 CARS1	1.68e-04	2	268	2	GO:0006423
GeneOntologyBiologicalProcess	granulosa cell proliferation	MTA3 MTOR	1.68e-04	2	268	2	GO:1990739
GeneOntologyBiologicalProcess	peptidyl-tyrosine autophosphorylation	PTK2B ALK IGF1R ROS1	1.70e-04	22	268	4	GO:0038083
GeneOntologyBiologicalProcess	negative regulation of calcium ion import across plasma membrane	PPP3CA PPP3CB PPP3CC	1.72e-04	9	268	3	GO:1905949
GeneOntologyBiologicalProcess	plasma membrane bounded cell projection morphogenesis	DAB2IP TRIO ANKRD27 SEMA3A SEMA6D SEMA5B UBE3A ARHGEF28 HDAC6 FEZF2 CAMK2B SMURF1 SPG11 LHX3 LMO4 CASK LIFR IGF1R PPP3CA PPP3CB CELSR3 DOCK7 RERE SEMA3E	1.86e-04	819	268	24	GO:0120039
GeneOntologyBiologicalProcess	cell projection morphogenesis	DAB2IP TRIO ANKRD27 SEMA3A SEMA6D SEMA5B UBE3A ARHGEF28 HDAC6 FEZF2 CAMK2B SMURF1 SPG11 LHX3 LMO4 CASK LIFR IGF1R PPP3CA PPP3CB CELSR3 DOCK7 RERE SEMA3E	2.11e-04	826	268	24	GO:0048858
GeneOntologyBiologicalProcess	positive regulation of glycogen metabolic process	INS PHKA1 PHKG2 INS-IGF2	2.41e-04	24	268	4	GO:0070875
GeneOntologyBiologicalProcess	SA node cell to atrial cardiac muscle cell signaling	RYR2 CACNA1G ANK2	2.43e-04	10	268	3	GO:0086018
GeneOntologyBiologicalProcess	SA node cell action potential	RYR2 CACNA1G ANK2	2.43e-04	10	268	3	GO:0086015
GeneOntologyCellularComponent	calcineurin complex	PPP3CA PPP3CB PPP3CC	4.33e-05	6	274	3	GO:0005955
MousePheno	abnormal telencephalon morphology	RTP1 TRIO IQSEC2 COPB2 PEX11B ARHGAP11A SEMA3A FZD9 UBE3A PIK3R2 PKD1 ASPM PEX2 HSD11B1 ARHGAP11B MICAL1 VN1R5 ANK2 FEZF2 SPG11 LMO4 THOC6 PPP3CA SLC25A12 CELSR3 MTOR PCSK6 TPH2 RERE	1.35e-05	812	211	29	MP:0000787
MousePheno	abnormal forebrain morphology	RTP1 TRIO IQSEC2 COPB2 PEX11B ARHGAP11A SEMA3A FZD9 KL UBE3A PIK3R2 PKD1 ASPM PEX2 HSD11B1 ALK ARHGAP11B MICAL1 VN1R5 ANK2 FEZF2 SPG11 LHX3 LMO4 ALG10B THOC6 PPP3CA SLC25A12 CELSR3 MTOR PCSK6 ALG10 TPH2 RERE	2.76e-05	1072	211	34	MP:0000783
Domain	Ank	ANKRD39 ANKS1B ANKLE1 ANKRD27 EHMT2 NFKBIA TONSL ESPN ANKRD42 ANK2 ESPNL TNNI3K ANKRD1 ANKRD60 TNKS	1.17e-06	228	269	15	PF00023
Domain	Ankyrin_rpt	RTP1 ANKRD39 ANKS1B ANKLE1 ANKRD27 EHMT2 NFKBIA TONSL ESPN ANKRD42 ANK2 ESPNL TNNI3K ANKRD1 ANKRD60 TNKS	1.37e-06	262	269	16	IPR002110
Domain	Ank_2	ANKRD39 ANKS1B ANKLE1 ANKRD27 EHMT2 NFKBIA TONSL ESPN ANKRD42 ANK2 ESPNL ANKRD1 ANKRD60 TNKS	3.01e-06	215	269	14	PF12796
Domain	ANK	ANKRD39 ANKS1B ANKLE1 ANKRD27 EHMT2 NFKBIA TONSL ESPN ANKRD42 ANK2 ESPNL TNNI3K ANKRD1 ANKRD60 TNKS	3.84e-06	251	269	15	SM00248
Domain	ANK_REPEAT	ANKRD39 ANKS1B ANKLE1 ANKRD27 EHMT2 NFKBIA TONSL ESPN ANKRD42 ANK2 ESPNL TNNI3K ANKRD1 ANKRD60 TNKS	4.23e-06	253	269	15	PS50088
Domain	Ankyrin_rpt-contain_dom	ANKRD39 ANKS1B ANKLE1 ANKRD27 EHMT2 NFKBIA TONSL ESPN ANKRD42 ANK2 ESPNL TNNI3K ANKRD1 ANKRD60 TNKS	4.44e-06	254	269	15	IPR020683
Domain	ANK_REP_REGION	ANKRD39 ANKS1B ANKLE1 ANKRD27 EHMT2 NFKBIA TONSL ESPN ANKRD42 ANK2 ESPNL TNNI3K ANKRD1 ANKRD60 TNKS	4.44e-06	254	269	15	PS50297
Domain	Tyr_kinase_rcpt_2_CS	INSRR ALK IGF1R ROS1	1.28e-05	11	269	4	IPR002011
Domain	-	ANKRD39 ANKS1B ANKLE1 ANKRD27 EHMT2 NFKBIA TONSL ESPN ANKRD42 ANK2 ESPNL ANKRD1 ANKRD60 TNKS	1.54e-05	248	269	14	1.25.40.20
Domain	-	ZNF142 ZFPM1 ZNF230 ZNF655 ZNF620 ZNF264 ZNF160 ZFP82 ZNF821 ZFAT FEZF2 WT1 OSR2 ZNF835 HINFP BCL6B ZNF532 ZNF665 ZNF197 ZNF69 ZNF70 ZFHX2 ZNF74 ZNF79 ZNF222	1.79e-05	679	269	25	3.30.160.60
Domain	RECEPTOR_TYR_KIN_II	INSRR ALK IGF1R ROS1	1.90e-05	12	269	4	PS00239
Domain	Znf_C2H2/integrase_DNA-bd	ZNF142 ZFPM1 ZNF230 ZNF655 ZNF620 ZNF264 ZNF160 ZFP82 ZNF821 ZFAT FEZF2 WT1 OSR2 ZNF835 HINFP BCL6B ZNF532 ZNF665 ZNF197 ZNF69 ZNF70 ZFHX2 ZNF74 ZNF79 ZNF222	2.57e-05	694	269	25	IPR013087
Domain	DUF3398	DOCK11 DOCK9 DOCK7	5.72e-05	6	269	3	PF11878
Domain	DOCK_C/D_N	DOCK11 DOCK9 DOCK7	5.72e-05	6	269	3	IPR021816
Domain	ZINC_FINGER_C2H2_2	ZNF142 ZFPM1 ZNF230 ZNF655 ZNF620 ZNF264 ZNF160 ZFP82 ZNF821 ZFAT FEZF2 WT1 OSR2 ZNF835 HINFP BCL6B ZNF532 ZNF665 ZNF197 HELZ2 ZNF69 ZNF70 ZFHX2 ZNF74 ZNF79 ZNF222	5.83e-05	775	269	26	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF142 ZFPM1 ZNF230 ZNF655 ZNF620 ZNF264 ZNF160 ZFP82 ZNF821 ZFAT FEZF2 WT1 OSR2 ZNF835 HINFP BCL6B ZNF532 ZNF665 ZNF197 HELZ2 ZNF69 ZNF70 ZFHX2 ZNF74 ZNF79 ZNF222	6.08e-05	777	269	26	PS00028
Domain	Znf_C2H2-like	ZNF142 ZFPM1 ZNF230 ZNF655 ZNF620 ZNF264 ZNF160 ZFP82 ZNF821 ZFAT FEZF2 WT1 OSR2 ZNF835 HINFP BCL6B ZNF532 ZNF665 ZNF197 HELZ2 ZNF69 ZNF70 ZFHX2 ZNF74 ZNF79 ZNF222	9.01e-05	796	269	26	IPR015880
Domain	AlbA_2	SLFN13 SLFN11 SLFNL1	9.91e-05	7	269	3	PF04326
Domain	Schlafen	SLFN13 SLFN11 SLFNL1	9.91e-05	7	269	3	IPR029684
Domain	Schlafen_AAA_dom	SLFN13 SLFN11 SLFNL1	9.91e-05	7	269	3	IPR007421
Domain	ZnF_C2H2	ZNF142 ZFPM1 ZNF230 ZNF655 ZNF620 ZNF264 ZNF160 ZFP82 ZNF821 ZFAT FEZF2 WT1 OSR2 ZNF835 HINFP BCL6B ZNF532 ZNF665 ZNF197 HELZ2 ZNF69 ZNF70 ZFHX2 ZNF74 ZNF79 ZNF222	1.15e-04	808	269	26	SM00355
Domain	Kinase-like_dom	SMG1 TRIO INSRR IRAK2 PTK2B PHKG2 MYLK3 NRK ALK MAP3K19 CAMK2B AAK1 GRK1 CASK TNNI3K IGF1R IKBKE MTOR ROS1 SBK2	1.22e-04	542	269	20	IPR011009
Domain	PROTEIN_KINASE_ATP	TRIO INSRR IRAK2 PTK2B PHKG2 MYLK3 NRK ALK MAP3K19 CAMK2B AAK1 GRK1 CASK TNNI3K IGF1R IKBKE ROS1 SBK2	1.27e-04	459	269	18	PS00107
Domain	TPR_REGION	SH3TC1 TONSL GPSM2 UTY TTC24 DNAH10 PTPN23 TTC7A CDC23 CFAP46	1.43e-04	165	269	10	PS50293
Domain	TPR	SH3TC1 TONSL GPSM2 UTY TTC24 DNAH10 PTPN23 TTC7A CDC23 CFAP46	1.43e-04	165	269	10	PS50005
Domain	TPR-like_helical_dom	COPB2 SH3TC1 TONSL GPSM2 UTY TTC24 COPS3 TRAPPC8 TTC7A MTOR CDC23 CFAP46	1.50e-04	233	269	12	IPR011990
Domain	Semaphorin	SEMA3A SEMA6D SEMA5B SEMA3E	1.70e-04	20	269	4	IPR027231
Domain	zf-C2H2	ZNF142 ZFPM1 ZNF230 ZNF655 ZNF620 ZNF264 ZNF160 ZFP82 ZFAT FEZF2 WT1 OSR2 ZNF835 HINFP BCL6B ZNF665 ZNF197 ZNF69 ZNF70 ZFHX2 ZNF74 ZNF79 ZNF222	1.84e-04	693	269	23	PF00096
Domain	Alg10	ALG10B ALG10	2.07e-04	2	269	2	IPR016900
Domain	Cys-tRNA-ligase	CARS2 CARS1	2.07e-04	2	269	2	IPR015803
Domain	Cys-tRNA/MSH_ligase	CARS2 CARS1	2.07e-04	2	269	2	IPR024909
Domain	DUF1712	CCZ1B CCZ1	2.07e-04	2	269	2	PF08217
Domain	tRNA-synt_1_cat_dom	CARS2 CARS1	2.07e-04	2	269	2	IPR032678
Domain	DIE2_ALG10	ALG10B ALG10	2.07e-04	2	269	2	PF04922
Domain	DUF1712_fun	CCZ1B CCZ1	2.07e-04	2	269	2	IPR013176
Domain	Znf_C2H2	ZNF142 ZFPM1 ZNF230 ZNF655 ZNF620 ZNF264 ZNF160 ZFP82 ZNF821 ZFAT FEZF2 WT1 OSR2 ZNF835 HINFP BCL6B ZNF532 ZNF665 ZNF197 ZNF69 ZNF70 ZFHX2 ZNF74 ZNF79 ZNF222	2.67e-04	805	269	25	IPR007087
Domain	Prot_kinase_dom	TRIO INSRR IRAK2 PTK2B PHKG2 MYLK3 NRK ALK MAP3K19 CAMK2B AAK1 GRK1 CASK TNNI3K IGF1R IKBKE ROS1 SBK2	2.75e-04	489	269	18	IPR000719
Domain	PROTEIN_KINASE_DOM	TRIO INSRR IRAK2 PTK2B PHKG2 MYLK3 NRK ALK MAP3K19 CAMK2B AAK1 GRK1 CASK TNNI3K IGF1R IKBKE ROS1 SBK2	3.04e-04	493	269	18	PS50011
Domain	TPR_7	TONSL GPSM2 TTC24	3.29e-04	10	269	3	PF13176
Domain	DHR-1_domain	DOCK11 DOCK9 DOCK7	4.48e-04	11	269	3	IPR027007
Domain	DHR_2	DOCK11 DOCK9 DOCK7	4.48e-04	11	269	3	PS51651
Domain	DHR_1	DOCK11 DOCK9 DOCK7	4.48e-04	11	269	3	PS51650
Domain	DHR-2	DOCK11 DOCK9 DOCK7	4.48e-04	11	269	3	PF06920
Domain	DOCK	DOCK11 DOCK9 DOCK7	4.48e-04	11	269	3	IPR026791
Domain	DOCK_C	DOCK11 DOCK9 DOCK7	4.48e-04	11	269	3	IPR010703
Domain	DOCK-C2	DOCK11 DOCK9 DOCK7	4.48e-04	11	269	3	PF14429
Domain	DHR-2	DOCK11 DOCK9 DOCK7	4.48e-04	11	269	3	IPR027357
Domain	CARMIL_C	CARMIL3 CARMIL2	6.14e-04	3	269	2	IPR031943
Domain	DUF2075	SLFN13 SLFN11	6.14e-04	3	269	2	PF09848
Domain	tRNA-synt_1e	CARS2 CARS1	6.14e-04	3	269	2	PF01406
Domain	Tyr_kinase_insulin-like_rcpt	INSRR IGF1R	6.14e-04	3	269	2	IPR016246
Domain	DUF2075	SLFN13 SLFN11	6.14e-04	3	269	2	IPR018647
Domain	CARMIL_C	CARMIL3 CARMIL2	6.14e-04	3	269	2	PF16000
Domain	PP2Ac	PPP3CA PPP3CB PPP3CC	7.59e-04	13	269	3	SM00156
Domain	Ser/Thr-sp_prot-phosphatase	PPP3CA PPP3CB PPP3CC	7.59e-04	13	269	3	IPR006186
Domain	SER_THR_PHOSPHATASE	PPP3CA PPP3CB PPP3CC	7.59e-04	13	269	3	PS00125
Domain	-	SH3TC1 TONSL GPSM2 UTY TTC24 TRAPPC8 TTC7A MTOR CDC23 CFAP46	8.67e-04	207	269	10	1.25.40.10
Domain	TPR_8	TONSL GPSM2 UTY TTC7A CDC23	9.75e-04	53	269	5	PF13181
Domain	Semap_dom	SEMA3A SEMA6D SEMA5B SEMA3E	9.75e-04	31	269	4	IPR001627
Domain	SEMA	SEMA3A SEMA6D SEMA5B SEMA3E	9.75e-04	31	269	4	PS51004
Domain	Sema	SEMA3A SEMA6D SEMA5B SEMA3E	9.75e-04	31	269	4	SM00630
Domain	Sema	SEMA3A SEMA6D SEMA5B SEMA3E	9.75e-04	31	269	4	PF01403
Domain	tRNAsynth_Ia_anticodon-bd	CARS2 MARS2 CARS1	1.18e-03	15	269	3	IPR009080
Domain	PC1	PKD1 PKD1L3	1.22e-03	4	269	2	IPR000434
Domain	Protein_kinase_ATP_BS	INSRR PTK2B PHKG2 MYLK3 NRK ALK MAP3K19 CAMK2B GRK1 TNNI3K IGF1R IKBKE ROS1 SBK2	1.26e-03	379	269	14	IPR017441
Domain	ARM-type_fold	SMG1 DOCK11 NOC2L ITPR2 AP2B1 ASPM EIF3K CIP2A DOCK9 UBR4 ARFGEF3 MTOR LTA4H	1.33e-03	339	269	13	IPR016024
Domain	TPR-contain_dom	SH3TC1 TONSL GPSM2 UTY TTC24 PTPN23 TTC7A CDC23	1.51e-03	150	269	8	IPR013026
Domain	Rho_GTPase_activation_prot	DAB2IP ARHGAP11A PIK3R2 ARHGAP11B ARAP3 RASAL3	1.71e-03	88	269	6	IPR008936
Domain	TPR_1	SH3TC1 GPSM2 UTY TTC24 TTC7A CDC23	1.91e-03	90	269	6	IPR001440
Domain	TPR_1	SH3TC1 GPSM2 UTY TTC24 TTC7A CDC23	1.91e-03	90	269	6	PF00515
Domain	FATC	SMG1 MTOR	2.01e-03	5	269	2	PF02260
Domain	Furin_repeat	INSRR IGF1R PCSK6	2.05e-03	18	269	3	IPR006212
Domain	FU	INSRR IGF1R PCSK6	2.05e-03	18	269	3	SM00261
Domain	Ser/Thr_kinase_AS	TRIO IRAK2 PHKG2 MYLK3 NRK MAP3K19 CAMK2B AAK1 GRK1 CASK TNNI3K IKBKE SBK2	2.11e-03	357	269	13	IPR008271
Domain	PROTEIN_KINASE_ST	TRIO IRAK2 PHKG2 MYLK3 NRK MAP3K19 CAMK2B AAK1 GRK1 CASK TNNI3K IKBKE SBK2	2.38e-03	362	269	13	PS00108
Domain	AA_TRNA_LIGASE_I	CARS2 MARS2 CARS1	2.41e-03	19	269	3	PS00178
Domain	TPR	SH3TC1 TONSL GPSM2 UTY TTC24 TTC7A CDC23	2.68e-03	129	269	7	SM00028
Domain	L_dom-like	FBXL8 CARMIL3 INSRR PRAMEF1 STK11IP FBXL3 FBXO38 TONSL PKD1 CARMIL2 IGF1R LRRC53	2.97e-03	328	269	12	IPR032675
Domain	RIH_assoc-dom	RYR2 ITPR2	2.98e-03	6	269	2	IPR013662
Domain	Ins145_P3_rec	RYR2 ITPR2	2.98e-03	6	269	2	PF08709
Domain	RIH_assoc	RYR2 ITPR2	2.98e-03	6	269	2	PF08454
Domain	RIH_dom	RYR2 ITPR2	2.98e-03	6	269	2	IPR000699
Domain	Ins145_P3_rcpt	RYR2 ITPR2	2.98e-03	6	269	2	IPR014821
Domain	Ryanodine_recept-rel	RYR2 ITPR2	2.98e-03	6	269	2	IPR015925
Domain	FAT	SMG1 MTOR	2.98e-03	6	269	2	PS51189
Domain	FATC	SMG1 MTOR	2.98e-03	6	269	2	PS51190
Domain	-	RYR2 ITPR2	2.98e-03	6	269	2	1.25.10.30
Domain	FATC_dom	SMG1 MTOR	2.98e-03	6	269	2	IPR003152
Domain	RYDR_ITPR	RYR2 ITPR2	2.98e-03	6	269	2	PF01365
Domain	PIK_FAT	SMG1 MTOR	2.98e-03	6	269	2	IPR014009
Domain	FATC	SMG1 MTOR	2.98e-03	6	269	2	SM01343
Pathway	BIOCARTA_HDAC_PATHWAY	INS IGF1R PPP3CA PPP3CB PPP3CC INS-IGF2	1.68e-06	26	207	6	MM1371
Pathway	KEGG_OOCYTE_MEIOSIS	INS ADCY2 ITPR2 CAMK2B IGF1R PPP3CA PPP3CB PPP3CC ESPL1 CDC23	6.25e-06	113	207	10	M16817
Pathway	KEGG_CALCIUM_SIGNALING_PATHWAY	ADCY2 RYR2 ITPR2 PHKA1 PTK2B PHKG2 MYLK3 CACNA1G CAMK2B PPP3CA PPP3CB PPP3CC	1.25e-05	178	207	12	M2890
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	TTYH1 ZSWIM8 ERCC1 TRIO IQSEC2 ANKS1B RNF40 STAB1 MAN1A2 MTA3 AP2B1 EHMT2 UBE3A ZNF655 PKD1 GPSM2 CARS2 MGAT5B ZNF821 HDAC6 ANK2 FEZF2 UBR4 HECTD4 MSH3 SIM2 LMO4 CASK FAIM PPP3CA PPP3CB CELSR3 ZNF532 CIAO3 PCSK6 ZNF197 TNKS	2.01e-11	1285	279	37	35914814
Pubmed	Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition.	FBXL8 INSRR IRAK2 RNF40 FBXL3 FBXO38 PTK2B MYLK3 ALK DET1 CAMK2B NR1H3 SIM2 TNNI3K IGF1R IKBKE ZNF74 SLFN11	1.66e-09	372	279	18	22939624
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SMG1 RNF40 ARHGAP11A ANKRD27 STAB1 MTA3 SEMA5B CACNA1G ARHGAP11B ZFP82 PDPR CEP162 HECTD4 AAK1 SPG11 CELSR3 ZNF532 PLCH2 PCNX1 ESPL1 SEMA3E	2.48e-09	529	279	21	14621295
Pubmed	Identification of novel fusion partners of ALK, the anaplastic lymphoma kinase, in anaplastic large-cell lymphoma and inflammatory myofibroblastic tumor.	ALK CARS1 RNF213	5.11e-07	3	279	3	12112524
Pubmed	Cloning and characterization of molecular isoforms of the catalytic subunit of calcineurin using nonisotopic methods.	PPP3CA PPP3CB PPP3CC	5.11e-07	3	279	3	2162844
Pubmed	Mitochondrial dysfunction and increased reactive oxygen species impair insulin secretion in sphingomyelin synthase 1-null mice.	INS SGMS1 INS-IGF2	5.11e-07	3	279	3	21115496
Pubmed	Stimulation of autophagy improves endoplasmic reticulum stress-induced diabetes.	INS MTOR INS-IGF2	5.11e-07	3	279	3	23274896
Pubmed	Klotho attenuates renal hypertrophy and glomerular injury in Ins2Akita diabetic mice.	INS KL INS-IGF2	5.11e-07	3	279	3	26586006
Pubmed	The proline-rich N-terminal sequence of calcineurin Abeta determines substrate binding.	PPP3CA PPP3CB PPP3CC	5.11e-07	3	279	3	19154138
Pubmed	Ablation of Rnf213 retards progression of diabetes in the Akita mouse.	INS RNF213 INS-IGF2	5.11e-07	3	279	3	23410753
Pubmed	Chromosomal mapping of the human genes for the calmodulin-dependent protein phosphatase (calcineurin) catalytic subunit.	PPP3CA PPP3CB PPP3CC	5.11e-07	3	279	3	1659808
Pubmed	mTORC1-independent reduction of retinal protein synthesis in type 1 diabetes.	INS MTOR INS-IGF2	5.11e-07	3	279	3	24740573
Pubmed	Defining the membrane proteome of NK cells.	MYO1G MAN1A1 GPAA1 CYP20A1 RNF40 PEX11B ANKRD27 ITPR2 MAN1A2 PIGA SGMS1 AP2B1 RBM19 PEX2 EIF3K ATG9A HSD11B1 ITM2B CARMIL2 DOCK9 UBR4 RNF213 MSH3 PARP14 RASAL3 MTOR HELZ2	9.95e-07	1168	279	27	19946888
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	DAB2IP TRIO RNF40 ANKLE1 ZFPM1 STK11IP ITPR2 SH3TC1 PLEKHM2 RBM19 PKD1 ATG9A SIPA1L2 DOCK9 UBR4 HECTD4 PIKFYVE IGF1R ARAP3 CELSR3 SLC16A5 ADAMTSL5 MTOR HELZ2 PCNX1 ESPL1	1.15e-06	1105	279	26	35748872
Pubmed	Genome-scale RNAi screen for host factors required for HIV replication.	SRD5A2 CHST13 SEMA5B RBM19 UTY RHOD FEZF2 AAK1 SMURF1 THOC6 TNFSF11 PCSK6 ANKRD1 OR52A1	1.57e-06	361	279	14	18976975
Pubmed	Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.	ZSWIM8 KLHDC2 IQSEC2 DAXX PAQR6 TRIM6 NPIPB5 ARHGAP11A TMEM161A SGMS1 SEMA6D PKD1 EIF3K ATG9A ARHGEF28 HDAC6 CEP162 DOCK9 OSR2 COPS3 CASK CIAO3 ZNF79	1.97e-06	925	279	23	28986522
Pubmed	Autocrine Action of IGF2 Regulates Adult β-Cell Mass and Function.	INS IGF1R INS-IGF2	2.03e-06	4	279	3	26384384
Pubmed	Molecular and phylogenetic analysis of calmodulin-dependent protein phosphatase (calcineurin) catalytic subunit genes.	PPP3CA PPP3CB PPP3CC	2.03e-06	4	279	3	1318721
Pubmed	Deletion of calcineurin and myocyte enhancer factor 2 (MEF2) binding domain of Cabin1 results in enhanced cytokine gene expression in T cells.	PPP3CA PPP3CB PPP3CC	2.03e-06	4	279	3	11714752
Pubmed	Insulin Dissociates the Effects of Liver X Receptor on Lipogenesis, Endoplasmic Reticulum Stress, and Inflammation.	INS NR1H3 INS-IGF2	2.03e-06	4	279	3	26511317
Pubmed	Regulation of dendritic cell function by insulin/IGF-1/PI3K/Akt signaling through klotho expression.	INS KL INS-IGF2	2.03e-06	4	279	3	27808000
Pubmed	Urinary semaphorin 3A correlates with diabetic proteinuria and mediates diabetic nephropathy and associated inflammation in mice.	INS SEMA3A INS-IGF2	2.03e-06	4	279	3	25249008
Pubmed	Glucoregulatory activity of vesiculin in insulin sensitive and resistant mice.	INS IGF1R INS-IGF2	2.03e-06	4	279	3	31018156
Pubmed	Hepatocyte nuclear factor-1 acts as an accessory factor to enhance the inhibitory action of insulin on mouse glucose-6-phosphatase gene transcription.	INS G6PC1 INS-IGF2	2.03e-06	4	279	3	9689059
Pubmed	The p48 DNA-binding subunit of transcription factor PTF1 is a new exocrine pancreas-specific basic helix-loop-helix protein.	INS PTF1A INS-IGF2	2.03e-06	4	279	3	8861960
Pubmed	Involvement of mTOR in Type 2 CRF Receptor Inhibition of Insulin Signaling in Muscle Cells.	INS MTOR INS-IGF2	2.03e-06	4	279	3	25875045
Pubmed	Decreased IGF1R attenuates senescence and improves function in pancreatic β-cells.	INS IGF1R INS-IGF2	2.03e-06	4	279	3	37441495
Pubmed	Antiaging gene Klotho enhances glucose-induced insulin secretion by up-regulating plasma membrane levels of TRPV2 in MIN6 β-cells.	INS KL INS-IGF2	2.03e-06	4	279	3	22597535
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	DAB2IP SMG1 RTEL1 STAB1 CACNA1G DOCK9 PTPN23 TTC7A HELZ2 PCNX1 UNC80	2.34e-06	225	279	11	12168954
Pubmed	Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.	DAB2IP TRIO IQSEC2 ANKS1B PTK2B AP2B1 ANK2 CAMK2B AAK1 PPP3CA PPP3CB MTOR	3.31e-06	281	279	12	28706196
Pubmed	TNFα signaling regulates cystic epithelial cell proliferation through Akt/mTOR and ERK/MAPK/Cdk2 mediated Id2 signaling.	NFKBIA PKD1 TNFSF11	5.05e-06	5	279	3	26110849
Pubmed	Sweet taste receptor signaling in beta cells mediates fructose-induced potentiation of glucose-stimulated insulin secretion.	INS TAS1R2 INS-IGF2	5.05e-06	5	279	3	22315413
Pubmed	Elevated expression of calcineurin subunits during active mineralization of developing mouse molar teeth.	PPP3CA PPP3CB PPP3CC	5.05e-06	5	279	3	22984995
Pubmed	Are calcineurin genes associated with endurance phenotype traits?	PPP3CA PPP3CB PPP3CC	5.05e-06	5	279	3	20107831
Pubmed	Polymorphisms in the calcineurin genes are associated with the training responsiveness of cardiac phenotypes in Chinese young adults.	PPP3CA PPP3CB PPP3CC	5.05e-06	5	279	3	20593291
Pubmed	Distinct roles for CARMIL isoforms in cell migration.	TRIO CARMIL3 CARMIL2	5.05e-06	5	279	3	19846667
Pubmed	Effects of ghrelin administration on decreased growth hormone status in obese animals.	INS DOCK7 INS-IGF2	5.05e-06	5	279	3	17595213
Pubmed	Calcineurin: form and function.	PPP3CA PPP3CB PPP3CC	5.05e-06	5	279	3	11015619
Pubmed	MicroRNA dysregulation in liver and pancreas of CMP-Neu5Ac hydroxylase null mice disrupts insulin/PI3K-AKT signaling.	INS CMAHP INS-IGF2	5.05e-06	5	279	3	25243123
Pubmed	Impaired insulin/IGF-1 is responsible for diabetic gastroparesis by damaging myenteric cholinergic neurones and interstitial cells of Cajal.	INS IGF1R INS-IGF2	5.05e-06	5	279	3	28931726
Pubmed	Beclin1 is essential for the pancreas development.	INS PTF1A INS-IGF2	5.05e-06	5	279	3	37739117
Pubmed	Age-regulated function of autophagy in the mouse inner ear.	INS ATG9A IGF1R INS-IGF2	5.16e-06	15	279	4	26235979
Pubmed	Endothelial cell interactions initiate dorsal pancreas development by selectively inducing the transcription factor Ptf1a.	INS PTF1A WT1 INS-IGF2	6.84e-06	16	279	4	14736742
Pubmed	A Sox9/Fgf feed-forward loop maintains pancreatic organ identity.	INS PTF1A G6PC1 INS-IGF2	6.84e-06	16	279	4	22874919
Pubmed	Cloning of six new genes with zinc finger motifs mapping to short and long arms of human acrocentric chromosome 22 (p and q11.2).	ZNF69 ZNF70 ZNF74	1.00e-05	6	279	3	1639391
Pubmed	Evidence of a developmental origin for β-cell heterogeneity using a dual lineage-tracing technology.	INS PTF1A INS-IGF2	1.00e-05	6	279	3	31160417
Pubmed	Mammalian brain phosphoproteins as substrates for calcineurin.	PPP3CA PPP3CB PPP3CC	1.00e-05	6	279	3	6330098
Pubmed	Insulin-like growth factor 2 is a key mitogen driving liver repopulation in mice.	INS IGF1R INS-IGF2	1.00e-05	6	279	3	29348399
Pubmed	Role of calcineurin, hnRNPA2 and Akt in mitochondrial respiratory stress-mediated transcription activation of nuclear gene targets.	NFKBIA IGF1R PPP3CA	1.00e-05	6	279	3	20153290
Pubmed	Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray.	DAB2IP INS PDE10A SORT1 SGMS1 UTY ANK2 AAK1 IGF1R SLC25A12 SLFN13 PCNX1 INS-IGF2	1.10e-05	371	279	13	15747579
Pubmed	Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.	EHMT2 ZNF655 ZNF620 ZNF264 ZNF160 ZFP82 RMND5B ZNF197 ZNF74	1.71e-05	181	279	9	37372979
Pubmed	The protein serine/threonine phosphatases PP2A, PP1 and calcineurin: A triple threat in the regulation of the neuronal cytoskeleton.	PPP3CA PPP3CB PPP3CC	1.75e-05	7	279	3	28126489
Pubmed	Low affinity Ca2+-binding sites of calcineurin B mediate conformational changes in calcineurin A.	PPP3CA PPP3CB PPP3CC	1.75e-05	7	279	3	11123943
Pubmed	Insulin-like growth factor II acts through an endogenous growth pathway regulated by imprinting in early mouse embryos.	INS IGF1R INS-IGF2	1.75e-05	7	279	3	1317321
Pubmed	Calcineurin binds the transcription factor NFAT1 and reversibly regulates its activity.	PPP3CA PPP3CB PPP3CC	1.75e-05	7	279	3	8631904
Pubmed	Characterization of pancreatic NMDA receptors as possible drug targets for diabetes treatment.	INS DOCK7 INS-IGF2	1.75e-05	7	279	3	25774850
Pubmed	Pancreas agenesis mutations disrupt a lead enhancer controlling a developmental enhancer cluster.	INS PTF1A INS-IGF2	1.75e-05	7	279	3	35998583
Pubmed	Irs-2 coordinates Igf-1 receptor-mediated beta-cell development and peripheral insulin signalling.	INS IGF1R INS-IGF2	1.75e-05	7	279	3	10471495
Pubmed	Expression of genes for insulin and insulin-like growth factors and receptors in early postimplantation mouse embryos and embryonal carcinoma cells.	INS IGF1R INS-IGF2	1.75e-05	7	279	3	1701096
Pubmed	Molecular genetics of successful smoking cessation: convergent genome-wide association study results.	TRIO ADCY2 ITPR2 RBM19 MYO18B USH2A TDRD5	1.79e-05	101	279	7	18519826
Pubmed	Growth-limiting role of endothelial cells in endoderm development.	INS PTF1A WT1 INS-IGF2	2.65e-05	22	279	4	21281624
Pubmed	Invariant Sema5A inhibition serves an ensheathing function during optic nerve development.	SEMA3A SEMA5B SEMA3E	2.78e-05	8	279	3	12506007
Pubmed	Gαi/o-coupled receptor signaling restricts pancreatic β-cell expansion.	INS PTF1A INS-IGF2	2.78e-05	8	279	3	25695968
Pubmed	Pdx-1 and Ptf1a concurrently determine fate specification of pancreatic multipotent progenitor cells.	INS PTF1A INS-IGF2	2.78e-05	8	279	3	18294628
Pubmed	SEL1L deficiency impairs growth and differentiation of pancreatic epithelial cells.	INS PTF1A INS-IGF2	2.78e-05	8	279	3	20170518
Pubmed	Pancreatic SEC23B deficiency is sufficient to explain the perinatal lethality of germline SEC23B deficiency in mice.	INS PTF1A INS-IGF2	2.78e-05	8	279	3	27297878
Pubmed	AKAP79/150 anchoring of calcineurin controls neuronal L-type Ca2+ channel activity and nuclear signaling.	PPP3CA PPP3CB PPP3CC	2.78e-05	8	279	3	17640527
Pubmed	Glucocorticoid signalling affects pancreatic development through both direct and indirect effects.	INS PTF1A INS-IGF2	2.78e-05	8	279	3	17001468
Pubmed	Biological pathway-based genome-wide association analysis identified the vasoactive intestinal peptide (VIP) pathway important for obesity.	NFKBIA PPP3CA PPP3CB PPP3CC	3.18e-05	23	279	4	20379146
Pubmed	Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations.	INS INSRR PIK3R2 NFKBIA NR1H3 IGF1R PPP3CA EHHADH MTOR G6PC1	3.81e-05	250	279	10	18660489
Pubmed	Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex.	PDE6A POF1B PHKA1 UBE3A SLC27A2 CAMK2B UBR4 RNF213 TRAPPC8 MTOR DOCK7	3.92e-05	304	279	11	32235678
Pubmed	In vitro fertilization causes epigenetic modifications to the onset of gene expression from the zygotic genome in mice.	INS IGF1R INS-IGF2	4.14e-05	9	279	3	11159375
Pubmed	Balanced interactions of calcineurin with AKAP79 regulate Ca2+-calcineurin-NFAT signaling.	PPP3CA PPP3CB PPP3CC	4.14e-05	9	279	3	22343722
Pubmed	SPATA33 localizes calcineurin to the mitochondria and regulates sperm motility in mice.	PPP3CA PPP3CB PPP3CC	4.14e-05	9	279	3	34446558
Pubmed	Expression patterns of epiplakin1 in pancreas, pancreatic cancer and regenerating pancreas.	INS PTF1A INS-IGF2	4.14e-05	9	279	3	18498355
Pubmed	PlexinA1 signaling directs the segregation of proprioceptive sensory axons in the developing spinal cord.	CADM4 SEMA3A FZD9 SEMA6D SEMA5B ITM2B SEMA3E	4.64e-05	117	279	7	17145500
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	SMG1 TRIO POF1B ITPR2 PHKA1 PTK2B PHKG2 MTA3 AP2B1 PIK3R2 NRK PEX2 EIF3K CAMK2B AAK1 CCNQ IGF1R IKBKE ESPL1 CDC23	5.33e-05	910	279	20	36736316
Pubmed	Systematic protein-protein interaction mapping for clinically relevant human GPCRs.	TTYH1 ERCC1 GPAA1 PAQR6 ADCY2 SLC22A17 TMEM161A CHPT1 EHMT2 SLC5A6 PKD1 YIPF3 UBR4 CCNQ SSPN PLCH2 CERS1	5.59e-05	697	279	17	28298427
Pubmed	Reduction of Ptf1a gene dosage causes pancreatic hypoplasia and diabetes in mice.	INS PTF1A INS-IGF2	5.88e-05	10	279	3	18591390
Pubmed	Trait-associated noncoding variant regions affect TBX3 regulation and cardiac conduction.	RYR2 RBM19 CACNA1G	5.88e-05	10	279	3	32672536
Pubmed	Role of nutrient-driven O-GlcNAc-post-translational modification in pancreatic exocrine and endocrine islet development.	INS PTF1A INS-IGF2	5.88e-05	10	279	3	32165492
Pubmed	A Specific CNOT1 Mutation Results in a Novel Syndrome of Pancreatic Agenesis and Holoprosencephaly through Impaired Pancreatic and Neurological Development.	INS PTF1A INS-IGF2	5.88e-05	10	279	3	31006513
Pubmed	Effects of mutations in the insulin-like growth factor signaling system on embryonic pancreas development and beta-cell compensation to insulin resistance.	INS IGF1R INS-IGF2	5.88e-05	10	279	3	12101187
Pubmed	Mesenchyme-derived IGF2 is a major paracrine regulator of pancreatic growth and function.	INS PTF1A INS-IGF2	5.88e-05	10	279	3	33057429
Pubmed	A piggyBac insertion disrupts Foxl2 expression that mimics BPES syndrome in mice.	COPB2 OSR2 FAIM	5.88e-05	10	279	3	24565867
Pubmed	Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins.	GPAA1 CARMIL3 COPB2 DAXX TMEM214 SLC22A17 TMEM161A AP2B1 UBE3A SIPA1L2 YIPF3 UBR4 AAK1 SLC25A12	5.89e-05	499	279	14	22810586
Pubmed	Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand.	INS SLC27A2 EHHADH G6PC1 INS-IGF2	6.12e-05	52	279	5	23260145
Pubmed	Mammalian target of rapamycin signaling inhibition ameliorates vascular calcification via Klotho upregulation.	KL MTOR	6.41e-05	2	279	2	26061549
Pubmed	Neuritic dystrophy and neuronopathy in Akita (Ins2(Akita)) diabetic mouse sympathetic ganglia.	INS INS-IGF2	6.41e-05	2	279	2	19111542
Pubmed	Progressive Thinning of Retinal Nerve Fiber Layer/Ganglion Cell Layer (RNFL/GCL) as Biomarker and Pharmacological Target of Diabetic Retinopathy.	INS INS-IGF2	6.41e-05	2	279	2	37628852
Pubmed	Decreased Satellite Cell Number and Function in Humans and Mice With Type 1 Diabetes Is the Result of Altered Notch Signaling.	INS INS-IGF2	6.41e-05	2	279	2	27335233
Pubmed	Bioinformatics Analysis of Weighted Genes in Diabetic Retinopathy.	INS INS-IGF2	6.41e-05	2	279	2	30480744
Pubmed	The implications of hyperoxia, type 1 diabetes and sex on cardiovascular physiology in mice.	INS INS-IGF2	6.41e-05	2	279	2	34845324
Pubmed	Thymic expression of mutated B16:A preproinsulin messenger RNA does not reverse acceleration of NOD diabetes associated with insulin 2 (thymic expressed insulin) knockout.	INS INS-IGF2	6.41e-05	2	279	2	16289958
Pubmed	Metabolomics Reveals a Key Role for Fumarate in Mediating the Effects of NADPH Oxidase 4 in Diabetic Kidney Disease.	INS INS-IGF2	6.41e-05	2	279	2	26203118
Pubmed	Identification of novel diabetes impaired miRNA-transcription factor co-regulatory networks in bone marrow-derived Lin-/VEGF-R2+ endothelial progenitor cells.	INS INS-IGF2	6.41e-05	2	279	2	29995913
Pubmed	Maternal diabetes adversely affects preovulatory oocyte maturation, development, and granulosa cell apoptosis.	INS INS-IGF2	6.41e-05	2	279	2	15718275
Pubmed	Protooncogenic Role of ARHGAP11A and ARHGAP11B in Invasive Ductal Carcinoma: Two Promising Breast Cancer Biomarkers.	ARHGAP11A ARHGAP11B	6.41e-05	2	279	2	38046902
Pubmed	Parental diabetes: the Akita mouse as a model of the effects of maternal and paternal hyperglycemia in wildtype offspring.	INS INS-IGF2	6.41e-05	2	279	2	23209676
Pubmed	Hyper-Variability in Circulating Insulin, High Fat Feeding Outcomes, and Effects of Reducing Ins2 Dosage in Male Ins1-Null Mice in a Specific Pathogen-Free Facility.	INS INS-IGF2	6.41e-05	2	279	2	27055260
Interaction	CALM3 interactions	IQSEC2 INSRR ITPR2 PHKA1 PHKG2 MYLK3 ASPM EIF3K ALK HDAC6 CAMK2B UBR4 IGF1R PPP3CA PPP3CB PPP3CC DOCK7 ROS1	9.64e-07	343	270	18	int:CALM3
GeneFamily	Ankyrin repeat domain containing	ANKRD39 ANKS1B ANKLE1 ANKRD27 EHMT2 NFKBIA TONSL ESPN ANKRD42 ANK2 ESPNL ARAP3 ANKRD1 ANKRD60 TNKS	7.83e-08	242	199	15	403
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF142 ZFPM1 ZNF230 ZNF655 ZNF620 ZNF264 ZNF160 ZFP82 ZNF821 ZFAT FEZF2 WT1 OSR2 ZNF835 HINFP BCL6B ZNF532 ZNF665 ZNF197 ZNF69 ZNF70 ZFHX2 ZNF74 ZNF79 ZNF222	3.60e-07	718	199	25	28
GeneFamily	Schlafen family	SLFN13 SLFN11 SLFNL1	4.45e-05	7	199	3	1110
GeneFamily	Immunoglobulin like domain containing\|Semaphorins	SEMA3A SEMA6D SEMA5B SEMA3E	6.01e-05	20	199	4	736
GeneFamily	Alpha-1,2-glucosyltransferases	ALG10B ALG10	1.21e-04	2	199	2	448
GeneFamily	Tetratricopeptide repeat domain containing\|Bardet-Biedl syndrome associated\|BBSome	SH3TC1 GPSM2 UTY TTC24 TTC7A CDC23 CFAP46	2.83e-04	115	199	7	769
GeneFamily	Protein phosphatase catalytic subunits\|EF-hand domain containing	PPP3CA PPP3CB PPP3CC	3.46e-04	13	199	3	693
GeneFamily	Mannosidases alpha class 1	MAN1A1 MAN1A2	7.13e-04	4	199	2	1193
GeneFamily	Receptor Tyrosine Kinases\|CD molecules	INSRR ALK IGF1R ROS1	9.54e-04	40	199	4	321
GeneFamily	Aminoacyl tRNA synthetases, Class I	CARS2 MARS2 CARS1	1.12e-03	19	199	3	131
ToppCell	3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell-Neuroendocrine\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FZD9 ESPN ANK2 FEZF2 PKD1L3 LRRC53 ESPL1 PCDH8 UNC80 KCNH5	3.57e-07	190	279	10	40d8b3403f4e38436b961cd3a2e69826cbae3042
ToppCell	3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FZD9 ESPN ANK2 FEZF2 PKD1L3 LRRC53 ESPL1 PCDH8 UNC80 KCNH5	3.57e-07	190	279	10	a9a705455019e28d655636de73b07540798f82e6
ToppCell	3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell-Neuroendocrine-Neuroendocrine_L.0.7.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FZD9 ESPN ANK2 FEZF2 PKD1L3 LRRC53 ESPL1 PCDH8 UNC80 KCNH5	3.57e-07	190	279	10	f6cbf6d292f488ada5f7581e1dceba6198b933d1
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_SEMA6D\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RTP1 PTK2B SEMA6D CMAHP MGAT5B LMO4 PLCH2 ROS1 KCNH5	1.52e-06	173	279	9	9a2d42f8d9cb834856522661d524abb91c4637c5
ToppCell	droplet-Limb_Muscle-nan-24m-Macroglial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CADM4 SRD5A2 ANKS1B PAQR6 SLC22A17 GPSM2 CAMK2B UNC80 SEMA3E	2.76e-06	186	279	9	ea936e66ae4b7b40564711fad60ac0137327995f
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	SEMA6D NRK CACNA1G ANK2 OSR2 LMO4 EFCC1 UNC80 SEMA3E	2.89e-06	187	279	9	5258674d0346e5c51a4b965efcdc1790c970845d
ToppCell	3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ITPR2 FZD9 ESPN ANK2 FEZF2 CAMK2B LRRC53 ESPL1 KCNH5	3.02e-06	188	279	9	1f912ea015f50570e848259d948a0ba682d64bb4
ToppCell	Bronchial-10x5prime-Epithelial-Epi_alveolar-Dividing_AT2\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	PDE6A CADM4 ZNF835 CELSR3 ADAMTSL5 ANKRD1 ROS1 TMEM262 SLFNL1	4.42e-06	197	279	9	49689a03ab31e53386dbe15c77c09ca3a14ebf4e
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_B0\|367C / Donor, Lineage, Cell class and subclass (all cells)	ITPR2 SH3TC1 USP42 PKD1 ZNF264 FAIM IKBKE TMEM39A	4.63e-06	149	279	8	41f28138bde45d0b814e116837e5a32b5e80d54a
ToppCell	368C-Myeloid-Macrophage-FABP4+_Macrophage\|368C / Donor, Lineage, Cell class and subclass (all cells)	MAN1A1 TNFSF13 PAQR5 SORT1 RRAGD PIK3R2 ARHGEF28 LTA4H	5.63e-06	153	279	8	e0fbbfd4d13031412e0b985322c8b99c56eb7af5
ToppCell	E15.5-Mesenchymal-mesenchymal_fibroblast-tracheal_fibroblast\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SLC22A23 RNF40 SLC22A17 FZD9 CACNA1G SIM2 THOC6 AGBL2	8.19e-06	161	279	8	9703b7e67d9fadb6129cad166bd01be915042e44
ToppCell	368C-Fibroblasts-Fibroblast-C_(Myofibroblast)\|368C / Donor, Lineage, Cell class and subclass (all cells)	RYR2 SGMS1 ZNF620 HSD11B1 MSH3 ALG10B ZNF197 ZNF222	1.12e-05	168	279	8	1bc6a1915d48f547385ed4f44e118bcc8a4a7b6c
ToppCell	368C-Fibroblasts-Fibroblast-C_(Myofibroblast)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	RYR2 SGMS1 ZNF620 HSD11B1 MSH3 ALG10B ZNF197 ZNF222	1.12e-05	168	279	8	69f534de0f9a293047bea03cb1b78551087a8df5
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RTP1 SEMA6D CMAHP MGAT5B LMO4 PLCH2 ROS1 KCNH5	1.22e-05	170	279	8	3174ea9cf93892a8b41de10fd4ff6f06bb41502d
ToppCell	Tuft-tuft-4\|World / Class top	MAN1A1 NOC2L ITPR2 PIGA CAMK2B SLC25A12 ETHE1 ZFHX2	1.44e-05	174	279	8	d6f306ebf66061bf9e9742000bfedce12d277452
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TEKT3 NYNRIN ZFP82 CIP2A RAB36 WDR97 IKBKE AGBL2	1.44e-05	174	279	8	e2243f1e48e3275753a2b3a69d06eefce69a8ded
ToppCell	CV-Severe-7\|CV / Virus stimulation, Condition and Cluster	SMG1 NPIPB5 ARHGAP11A UTY RNF213 PARP14 ALG10 TNKS	1.56e-05	176	279	8	3de0c7d77210049e5616db21eed1490a17a5ec2d
ToppCell	390C-Lymphocytic-ILC-ILC-1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	STK11IP TONSL SLC27A2 TTC24 ZFAT CARMIL2 THOC6 WDR97	1.77e-05	179	279	8	3edcd1356e49b1f5514c585861999e079ca5e579
ToppCell	3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_B-Branch_B2_(eMN)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TMC3 ARHGEF28 ANK2 CAMK2B KCNH4 ZFHX2 UNC80 KCNH5	1.84e-05	180	279	8	368ff7fcfd21ad248f96a83a8b191040ba7d8670
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TMC3 SEMA3A KL SEMA5B FEZF2 IKBKE SEMA3E KCNH5	2.07e-05	183	279	8	65f2a5895d166189a095cf7ea9dda171f0419b08
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CARMIL3 CADM4 PAQR6 SLC22A17 TONSL MSS51 CAMK2B SEMA3E	2.07e-05	183	279	8	8330c39184ce076e1f95fd3725b68af551d89db0
ToppCell	droplet-Lung-nan-3m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTYH1 STAB1 SEMA3A PHKA1 PIGA BCL6B PCSK6 EFCC1	2.24e-05	185	279	8	6a85399cfdb9b89683c874e7f046957f9a601dc2
ToppCell	droplet-Lung-nan-3m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTYH1 STAB1 SEMA3A PHKA1 PIGA BCL6B PCSK6 EFCC1	2.24e-05	185	279	8	64791056cdbb739136dbef08f4b16e2b5427faad
ToppCell	systemic_lupus_erythematosus-managed-Lymphocytic_NK-NK_bright-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	TTYH1 PAQR6 NFKBIA UTY TNFSF11 SLFN13 PLCH2 ANKRD60	2.24e-05	185	279	8	3b2da51aec057b462749ae39afb8f253afcf38d5
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_B0\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	ITPR2 SH3TC1 USP42 PKD1 ZNF264 FAIM IKBKE TMEM39A	2.33e-05	186	279	8	74c238759c5d3fd39127ec0060d0c2cb16b326d4
ToppCell	368C-Lymphocytic-CD4_T-cell-Treg_cell_3\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	MAN1A1 ANKS1B TATDN2 SH3TC1 RBM19 RNF213 SLFNL1 CDC23	2.42e-05	187	279	8	689b3cc76f1e04bd35a7d3ce19e9f08744a7835b
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_B0\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	ITPR2 SH3TC1 USP42 PKD1 ZNF264 FAIM IKBKE TMEM39A	2.42e-05	187	279	8	816d37a70f7ec382a268fe828b3dfe737a36a4bf
ToppCell	facs-Heart-RA-24m-Mesenchymal-ventricular_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RYR2 MYLK3 RRAGD TMEM163 MYO18B TNNI3K ANKRD1 SBK2	2.61e-05	189	279	8	b98f60875b1a12b2ec9dc91889298ae57f98602f
ToppCell	facs-Heart-RA-24m-Mesenchymal-ventricular_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RYR2 MYLK3 RRAGD TMEM163 MYO18B TNNI3K ANKRD1 SBK2	2.61e-05	189	279	8	e758b264c0a47127e33e66c395cf5a3224c7305b
ToppCell	3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_B-Branch_B1_(eMN)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ALK ARHGEF28 ANK2 ARFGEF3 CELSR3 ZFHX2 UNC80 KCNH5	2.92e-05	192	279	8	d8f5df2c2a50e567f24ebecc8033ac97ba89d9c5
ToppCell	droplet-Heart-nan-24m-Mesenchymal-cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RYR2 MYLK3 RRAGD TMEM163 MYO18B TNNI3K ANKRD1 SBK2	2.92e-05	192	279	8	f6a4e348406a852ace9fb21db8fbdff539217645
ToppCell	droplet-Heart-nan-24m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RYR2 MYLK3 RRAGD TMEM163 MYO18B TNNI3K ANKRD1 SBK2	2.92e-05	192	279	8	1a0c25106ae08eac912a4edd5fc1a3ee776f69c2
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PAQR5 ITPR2 SEMA6D RRAGD NRK ANK2 SIM2 ARFGEF3	2.92e-05	192	279	8	ee27d27e3d269764dbe8711d0b37ff9331a298a9
ToppCell	3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_B\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ALK ARHGEF28 ANK2 ARFGEF3 CELSR3 ZFHX2 UNC80 KCNH5	3.03e-05	193	279	8	9661ea0ee7273928c7de2a9f49e853595fa77699
ToppCell	wk_08-11-Hematologic-Meg-ery-Definitive_erythroblast\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	SLC22A23 ANKLE1 ZFPM1 PTK2B ESPN ATG2B HECTD4 PKD1L3	3.03e-05	193	279	8	be75abfdf5301cf33df8ee9ed92504d44fdf19a6
ToppCell	facs-Large_Intestine-Distal-18m-Epithelial-Reg4/cKit+_deep_crypt_secretory_cells_(Distal)\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP20A1 TMEM214 FZD9 ST3GAL6 MICAL1 ARFGEF3 SLC25A12 TMEM39A	3.15e-05	194	279	8	0797245ebfa389a6f66874cb0f11297f1456e600
ToppCell	facs-Large_Intestine-Distal-18m-Epithelial-secretory_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP20A1 TMEM214 FZD9 ST3GAL6 MICAL1 ARFGEF3 SLC25A12 TMEM39A	3.15e-05	194	279	8	0241b4b88d6210b4c1b8aa99db17115b18142f01
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CARMIL3 INS INSRR TMEM163 UTY HDAC6 RERE UNC80	3.26e-05	195	279	8	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	facs-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIO INS INSRR ANK2 ARFGEF3 IGF1R ZFHX2 UNC80	3.26e-05	195	279	8	bd8e24dd598990204998d1dd853ba7a53dc0107e
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CARMIL3 INS INSRR TMEM163 UTY HDAC6 RERE UNC80	3.26e-05	195	279	8	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FZD9 KLHDC7A WT1 PKD1L3 CELSR3 LRRC53 UNC80 KCNH5	3.38e-05	196	279	8	95544097577f20ed7f4144bd940471cde0617554
ToppCell	IPF-Lymphoid-T\|Lymphoid / Disease state, Lineage and Cell class	RYR2 SH3TC1 NFKBIA DOCK9 AAK1 CASK PCNX1 PRORP	3.38e-05	196	279	8	6e70c48a63d9673eb16b0847c1bd88eecc2f7a3c
ToppCell	Neuronal\|World / cells hierarchy compared to all cells using T-Statistic	ANKS1B RYR2 MAN1A2 UBE3A PKD1 CAMK2B AAK1 UNC80	3.91e-05	200	279	8	48d801219bc771d6c7e151dc88ca4c179988de85
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW08-Mesenchymal\|GW08 / Sample Type, Dataset, Time_group, and Cell type.	ZNF142 RRAGD SH3TC1 OSR2 TSEN54 LIFR SLFN11 UNC80	3.91e-05	200	279	8	e5b7d9622b96bb20c81ac76b4e60e8b44fa9cca1
ToppCell	MS-CD4-CD8_1\|MS / Condition, Cell_class and T cell subcluster	TMC3 MYLK3 KLHDC7A SIPA1L2 CIP2A ARAP3 ZNF222	4.52e-05	150	279	7	7dc95c58b98d8c4c6c49fb1a03ec6ac24fb41f54
ToppCell	facs-Liver-Non-hepatocytes-3m-Lymphocytic-NK_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MSS51 UTY MICAL1 DET1 CAMK2B PPP3CC RASAL3	5.34e-05	154	279	7	75eac6970259a6916fcfa6d3400509cfa2d98d9d
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Tac1_Htr1d\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SEMA3A ST3GAL6 SLC27A2 WT1 TNNI3K TNFSF11 PCDH8	5.57e-05	155	279	7	79264ff283e36a059040a5aa9fe7337be694cb52
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Pld5\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ZFPM1 PTK2B KCNS1 ESPN LMO4 KCNH4 KCNH5	6.54e-05	159	279	7	a082e770fa757c4a1d3ed13d53f83297e36faf05
ToppCell	COVID-19-kidney-Technical/muscle_(Mes)\|kidney / Disease (COVID-19 only), tissue and cell type	ADCY2 RYR2 SEMA3A MYO18B USH2A ALK KCNH5	6.54e-05	159	279	7	5335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADCY2 RYR2 SEMA3A USH2A DNAH10 SIM2 UNC80	6.80e-05	160	279	7	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADCY2 RYR2 SEMA3A USH2A DNAH10 SIM2 UNC80	6.80e-05	160	279	7	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	facs-Lung-nan-3m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INS RYR2 CHST13 SEMA5B DNAH10 PLCH2 RAPGEFL1	6.80e-05	160	279	7	f2cdee5a9e3b0eb125d6be7b5d239eb04333ae41
ToppCell	Globus_pallidus-Neuronal-Excitatory\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	PDE10A PTK2B KCNS1 CAMK2B KCNH4 PPP3CA KCNH5	6.80e-05	160	279	7	f843287ed57d2d5a3b3f6dfb03b6934e330e6645
ToppCell	Globus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	PDE10A PTK2B KCNS1 CAMK2B KCNH4 PPP3CA KCNH5	7.07e-05	161	279	7	ebcd5066e82b7760b9da6adc02d11258d1309dab
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ANKS1B USH2A TDRD5 DNAH10 CIP2A ROS1 UNC80	7.35e-05	162	279	7	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	droplet-Lung-nan-18m-Lymphocytic-plasma_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAN1A1 CARMIL3 PIGA CMAHP SRBD1 PKD1L3 PPP3CC	7.64e-05	163	279	7	5efecdd8a069a822bc9d35b407092925a865e629
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c04-ANXA2\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CARMIL3 ASPM MSS51 ARHGAP11B CCNQ ZNF79 DCAF4	7.64e-05	163	279	7	ce07bc424ef99c547588b07f5c8b39ff0773ca9b
ToppCell	Control-APC-like-Monocytes\|Control / group, cell type (main and fine annotations)	TNFSF13 STK11IP SLC5A6 TDRD5 IKBKE ZNF665 FCRL5	7.64e-05	163	279	7	4bc80a2c741d462724b6f3902377d48c57478932
ToppCell	droplet-Lung-nan-18m-Lymphocytic-Plasma_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAN1A1 CARMIL3 PIGA CMAHP SRBD1 PKD1L3 PPP3CC	7.64e-05	163	279	7	0d94a427f86e62aba12c397c6d7b8cd297f3a0e5
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-plasma_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MAN1A1 CARMIL3 PIGA CMAHP SRBD1 PKD1L3 PPP3CC	7.94e-05	164	279	7	b92e7c91910d518627376166c6ea9ed333b3d07e
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-plasma_cell-plasma_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MAN1A1 CARMIL3 PIGA CMAHP SRBD1 PKD1L3 PPP3CC	7.94e-05	164	279	7	a1e43c6b3e2553f5604100db6e92bf244b70c36d
ToppCell	facs-Lung-nan-3m-Epithelial-type_I_pneumocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CADM4 POF1B SEMA3A ARHGEF28 ARFGEF3 ANKRD1 SEMA3E	8.57e-05	166	279	7	11b0ae82b3068ef91715dbdd49fe8e9791b4a480
ToppCell	facs-Lung-nan-3m-Epithelial-Alveolar_Epithelial_Type_1\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CADM4 POF1B SEMA3A ARHGEF28 ARFGEF3 ANKRD1 SEMA3E	8.57e-05	166	279	7	fcc1aec31ebd39432d4cb284dc8fadf34e3c566a
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.1.3\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IRAK2 PIGA NFKBIA WDR97 GLIPR1L2 TMEM262 PRORP	8.90e-05	167	279	7	8fede587572d465cb63f7828141a574185bbb819
ToppCell	droplet-Kidney-nan-18m-Epithelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MSS51 MGAT5B TDRD5 WT1 ADAMTSL5 EFCC1 SEMA3E	9.58e-05	169	279	7	87116c33c5ca8cb1862e103e5607b1df4d264569
ToppCell	facs-Lung-18m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l21\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ASPM METTL22 ZFP82 ESPN PPP3CB RASAL3 IKBKE	9.94e-05	170	279	7	bda900c836e0f2c1d7b442beb50b672d025b2420
ToppCell	facs-Lung-3m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l21\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RBM19 CMAHP METTL22 ZFAT PKD1L3 BCDIN3D IKBKE	1.03e-04	171	279	7	f1fdc0ec3399ed6955976d02be7e5fc329a64276
ToppCell	COVID-19_Mild-Neu_2\|COVID-19_Mild / 5 Neutrophil clusters in COVID-19 patients	SORT1 GPSM2 CAMK2B CCNQ ARFGEF3 CIAO3 ETHE1	1.07e-04	172	279	7	f5fd08b42c002d4693646b27e7b708eceb49524f
ToppCell	facs-Heart-Unknown-3m-Mesenchymal-atrial_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RYR2 MYLK3 TMEM163 MYO18B TNNI3K ANKRD1 SBK2	1.07e-04	172	279	7	ee8ce9e8c9a6d3ee2be113f77743958005f4b3f0
ToppCell	facs-Heart-Unknown-3m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RYR2 MYLK3 TMEM163 MYO18B TNNI3K ANKRD1 SBK2	1.07e-04	172	279	7	bd468a7ea6ec832dcf6a816a1e0c03fa0f176dad
ToppCell	facs-Diaphragm-Limb_Muscle-24m-Mesenchymal\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RYR2 NFKBIA USH2A ESPN DNAH10 KCNH4 ANKRD1	1.11e-04	173	279	7	66f37c1437705734b20601656fa4aa1d92ca30be
ToppCell	facs-Diaphragm-Limb_Muscle-24m-Mesenchymal-nan\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RYR2 NFKBIA USH2A ESPN DNAH10 KCNH4 ANKRD1	1.11e-04	173	279	7	649b08a409095592cccf31883be69c754411280d
ToppCell	ASK452-Immune-B_cell\|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq	ITPR2 STAB1 SLC5A6 ZFP82 SHLD1 RASAL3 DOCK7	1.15e-04	174	279	7	69723f5666abc3af5f0431901a60246c9915ef81
ToppCell	PBMC-Convalescent-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-14\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ARHGAP11A ZNF264 ZNF821 DET1 PTPN23 SSPN FCRL5	1.19e-04	175	279	7	87e557f7508c88b2087db5d57e77d5e2c92ca083
ToppCell	3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ZNF142 DOCK11 CIP2A SPG11 TTC7A GLIPR1L2 DCAF4	1.23e-04	176	279	7	76fdf211bce101e83a27d822cb399487bd107027
ToppCell	COVID-19-Heart-CM_3\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PDE10A RYR2 SORT1 ST3GAL6 MYO18B ANK2 ANKRD1	1.23e-04	176	279	7	9df7a124ebafb0087da0cda133a394275d7bed81
ToppCell	CV-Severe-7\|Severe / Virus stimulation, Condition and Cluster	SMG1 NPIPB5 ARHGAP11A UTY RNF213 ALG10 TNKS	1.28e-04	177	279	7	82fdd6185b368f54f03de389427cbe3071d21a99
ToppCell	wk_15-18-Mesenchymal-Chondrocyte-ASPN+_chondrocyte\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	ADCY2 FZD9 NRK KCNS1 ZFAT SIM2 SLC25A12	1.32e-04	178	279	7	a55130670aa95a87b833dd3cd2de461d779e4c06
ToppCell	PND28-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CADM4 POF1B SEMA3A ARHGEF28 RHOD ANKRD1 SEMA3E	1.32e-04	178	279	7	a3af5d9c55858e36be0498081029ecb0acaeb3d3
ToppCell	PND28-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CADM4 POF1B SEMA3A ARHGEF28 RHOD ANKRD1 SEMA3E	1.32e-04	178	279	7	b3b88989bd602cfb55bb5c47731deb99288a8952
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MAN1A1 ITPR2 PTK2B KCNS1 MGAT5B LMO4 PCDH8	1.32e-04	178	279	7	ccea3c8908d72f5fecd151a133048c8e9758304c
ToppCell	Dividing_Macrophages-IPF_02\|World / lung cells shred on cell class, cell subclass, sample id	RTEL1 ARHGAP11A ASPM ARHGAP11B TRAPPC8 ESPL1 PCDH8	1.32e-04	178	279	7	1893fadac2ec3d5de0a641e57b7b2f962012a9ba
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SRD5A2 PLAAT2 MAP3K19 WDR97 SLFN13 AGBL2 CFAP46	1.32e-04	178	279	7	3b12db04006db6e94fc45649a4b3a63b92f21a61
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RTP1 MYLK3 SEMA6D CMAHP MGAT5B LMO4 KCNH5	1.32e-04	178	279	7	0e1bedf991189d0ef9b40dac9281bdf4739333a1
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTK2B SEMA6D CMAHP MGAT5B LMO4 ROS1 KCNH5	1.37e-04	179	279	7	8766a5a066091879f521acfc612abf563ff78808
ToppCell	droplet-Bladder-nan-24m-Epithelial-endothelial_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTYH1 CADM4 ANKS1B PAQR6 CAMK2B PCSK6 SEMA3E	1.37e-04	179	279	7	3d6bb3cfe89d60f2f00aead9341f9967e5313763
ToppCell	wk_15-18-Epithelial-PNS-KCNIP4+_neuron\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	TMC3 MGAT5B ALK ARHGEF28 ANK2 FSCN3 KCNH4	1.37e-04	179	279	7	e20bfdfb6d5af8556eb66b81a19fbe4e3e28334a
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TMC3 SEMA3A KL SEMA5B FEZF2 SEMA3E KCNH5	1.37e-04	179	279	7	f65889bf1e41396979cce44a5e63f49dea2bbd9b
ToppCell	390C-Lymphocytic-ILC-ILC-1\|390C / Donor, Lineage, Cell class and subclass (all cells)	STK11IP TONSL SLC27A2 TTC24 ZFAT CARMIL2 WDR97	1.37e-04	179	279	7	e7045e27f0eb88f552b31c04b56d78e5ccd7a36c
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PAQR5 SEMA6D RRAGD NRK ANK2 SIM2 ARFGEF3	1.42e-04	180	279	7	a17dbe03597b81e7a1fe2bf2d23e59e55c615a2a
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PAQR5 SEMA6D RRAGD NRK ANK2 SIM2 ARFGEF3	1.42e-04	180	279	7	eee71184ebed2694d3e60f579a44b3cf7dd2cd35
ToppCell	10x5'-bone_marrow-Hematopoietic_progenitors-Cycling_pre-Myeloid-1\|bone_marrow / Manually curated celltypes from each tissue	TNFSF13 ARHGAP11A MYLK3 ASPM GPSM2 CIP2A ESPL1	1.47e-04	181	279	7	ccd0ed30cea3fb41d34f28b3e8d80a94493bef3c
ToppCell	wk_15-18-Hematologic-Meg-ery-Definitive_erythroblast\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	SLC22A23 PTK2B ATG9A MYO18B ESPN ATG2B HECTD4	1.52e-04	182	279	7	93841f730ca1a735eaaf5f2ccbe5c45ab0e029d1
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Macroglial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTYH1 CADM4 ANKS1B GPSM2 CAMK2B UNC80 SEMA3E	1.52e-04	182	279	7	82ca6d5ed48b4c487ce00b9309255abb8f20b61d
ToppCell	droplet-Lung-nan-21m-Lymphocytic-Ly6g5b+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ST3GAL6 LMO4 IGF1R TNFSF11 RASAL3 SLFNL1 KCNH5	1.57e-04	183	279	7	302bd0f1f8025f385a764f2a9adafdd7f1f67ea3
ToppCell	Control-T/NK_proliferative\|Control / Disease group and Cell class	IQSEC2 ARHGAP11A ASPM GPSM2 ARHGAP11B NR1H3 ESPL1	1.57e-04	183	279	7	09c2b4e630f1c338f02c1242e3598e870d6b0a28
ToppCell	droplet-Kidney-nan-21m-Epithelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAT5B TDRD5 DNAH10 FSCN3 WT1 ADAMTSL5 SEMA3E	1.57e-04	183	279	7	f55081068213cc1cdb2acad58ff10f6b48b44c72
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RYR2 NRK USH2A DNAH10 ARFGEF3 ROS1 UNC80	1.62e-04	184	279	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RYR2 NRK USH2A DNAH10 ARFGEF3 ROS1 UNC80	1.62e-04	184	279	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	droplet-Limb_Muscle-nan-21m-Macroglial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTYH1 CADM4 ANKS1B PAQR6 CAMK2B UNC80 SEMA3E	1.62e-04	184	279	7	9f8cd5ab5af6c35a1be25d70a125b9a3f4dd667a
Drug	MolPort-016-580-972	PTK2B PIK3R2 NFKBIA TONSL SIM2 PIKFYVE TNFSF11 MTOR	1.49e-07	51	271	8	CID009938589

Protein segments in the cluster

Peptide	Gene	Start	Entry
DNCEHFVNHLRYGVS	PLAAT2	111	Q9NWW9
YFHHVLRTEGHAIVC	TDRD5	646	Q8NAT2
ALLHCRSLHKDYGAA	TTYH1	366	Q9H313
FLNVTNYCHLAHELR	DCAF4	136	Q8WV16
CNAAFGAHDFHRIYI	RNF40	986	O75150
VKEYDRAAHFLHGCN	CDC23	96	Q9UJX2
VHLEQYADTFRRHGL	ARAP3	16	Q8WWN8
LHCFQHVVAVEAYTR	ANKLE1	536	Q8NAG6
DELICHIGSLASVYH	AP2B1	561	P63010
EHIRYATDTFAGLCH	COPS3	91	Q9UNS2
PFNHEILREAYALCH	COPS6	251	Q7L5N1
NILLHDRGHYVLCDF	AAK1	181	Q2M2I8
AVRTGHYECAEHLIA	ANKRD1	226	Q15327
AQECLHHAQDYGGLL	COPB2	686	P35606
EFLAHLSSLCHYLLV	BCDIN3D	181	Q7Z5W3
VDTIYHRQGCRHFSL	CARMIL2	181	Q6F5E8
LESYLCSFVHLNHPL	FAM106A	26	Q4KMX7
VASHRGHFDAVQYLL	ANKRD60	226	Q9BZ19
GLSDLYHLRLAHACS	CFAP46	1496	Q8IYW2
ALRIHEHAAIYLTAC	BTBD11	226	A6QL63
VLLNARCDLHAVNYH	EHMT2	836	Q96KQ7
RCDLHAVNYHGDTPL	EHMT2	841	Q96KQ7
HIAARESYHDCVLLF	EHMT2	856	Q96KQ7
HLPQAQRYCEGHFSL	ALG10B	41	Q5I7T1
LLHEYRNGASIHEFC	CCM2	321	Q9BSQ5
LHRASYCGHTEIARL	ANKRD39	101	Q53RE8
YCGHTEIARLLLSHG	ANKRD39	106	Q53RE8
DSYHGALCLRFQAQH	CCNQ	176	Q8N1B3
SHCLELGAASAHYIA	HSD11B1	76	P28845
YSLHIIDLHTGRLCD	DET1	191	Q7L5Y6
ERRHLDLIYNFGCHL	DAXX	326	Q9UER7
DQYLQEVFHHLDCRG	EFCC1	56	Q9HA90
VSFSDGRVLCYLIHH	ASPM	1136	Q8IZT6
VFAEACSHDHLRFIG	ATG2B	566	Q96BY7
HYAAFHGRLGCLQLL	ANKRD42	136	Q8N9B4
AEFLTFHYARLCGAL	RASAL3	436	Q86YV0
HSVCHLYFRGANAAL	RAB17	81	Q9H0T7
FNALCHSTHLYGRRL	RBM19	891	Q9Y4C8
YTPEACLQLREHFHG	RAB36	91	O95755
CLLADHTVHVLRYFF	ARHGAP11B	161	Q3KRB8
ICFGRRYDHNHQELL	CYP1A1	201	P04798
VNQHLCGSHLVEALY	INS	26	P01308
HFQCAAGAFAYLREH	PTPN23	146	Q9H3S7
FVHCIETHGRHVEYL	ITPR2	1296	Q14571
SRYLLSVCGFRFHHQ	NPIPB12	486	F8W0I5
RFDYIGHSHQLFHVC	PAQR5	246	Q9NXK6
HTVYLERHICGRLFG	LTA4H	321	P09960
FFRRSVIKGAHYICH	NR1H3	121	Q13133
CLDELLEIHRHFFYS	ARHGEF28	896	Q8N1W1
LTALHVAAHCGHYRV	ANK2	366	Q01484
YACSGGHHELVALLL	ANKRD27	816	Q96NW4
ALHCAAQYGHSEVVA	ANKS1B	131	Q7Z6G8
LLADLHAFCQAHSYD	PRUNE1	266	Q86TP1
KEFAEHITNHYLGLC	DAB2IP	346	Q5VWQ8
AARELNIYCHLDHNF	MSH3	266	P20585
LEALRYCHDNNIIHR	CASK	126	O14936
YLACQEGHLHLAQFL	ESPNL	176	Q6ZVH7
ALHLAVTFLHYGCAT	OR10AC1	246	Q8NH08
LVLNTCIIHYRHQEF	KIAA0100	371	Q14667
THYLLGNFRDAVIAH	GPSM2	211	P81274
FLAALAQGVLEHHTY	GPAA1	581	O43292
HIIHAAIFICNYAPG	GLIPR1L2	181	Q4G1C9
VHFGCFAVSVAQHLY	IL17REL	76	Q6ZVW7
NIDHLGFFIYRLCHD	ITM2B	211	Q9Y287
CAVEYLHGLEIIHSN	IRAK2	321	O43187
GTIQLSAHRGLYHDF	MSS51	321	Q4VC12
DRFHYINGSLFCEHD	LMO4	126	P61968
CGDEVARYLDHLLAH	PHKA1	656	P46020
FDEPLCAHEARNYHT	LRRC53	336	A6NM62
SLGEYQCLLELHGFH	ASMTL	586	O95671
GYTARERDVAQCHLH	IQSEC2	146	Q5JU85
LSDFNGHSHCTRYLR	ESPN	311	B1AK53
APRHQEYLFEGHLCV	IKBKE	346	Q14164
FQTIHCAPGDLIYHA	KCNH5	566	Q8NCM2
LHGCCSHLTYLNLAR	CARMIL3	386	Q8ND23
ALGCHYRIAHAEAQV	EHHADH	106	Q08426
TCALFLSLRYHNLHP	ERCC1	136	P07992
FTLYRIDIHSCNHEA	IGF1R	796	P08069
LERIHAYIQHQDFCR	MGAT5B	631	Q3V5L5
FYEHLTRSLQHSLCG	PCNX1	1556	Q96RV3
ATQCLSCRRGFYHHQ	PCSK6	761	P29122
LYQFHHEGAALERRS	FCRL5	411	Q96RD9
VAICYPLRHANIFTH	OR52A1	126	Q9UKL2
QVRCALYGHEHFRLQ	PCDH8	426	O95206
YSLERHVCLGFVHNF	PDPR	806	Q8NCN5
FTRQICEGVHYLHQH	MYLK3	616	Q32MK0
LCHDLDHRGFSNSYL	PDE10A	551	Q9Y233
LEERCYDLFRNHHLA	PEX2	116	P28328
HLSYLHNCETRRGQI	PDE6A	226	P16499
AFCHDIDHRGTNNLY	PDE6A	596	P16499
ACRVSFHSLEAYLAH	ZFPM1	821	Q8IX07
ALEGHQEHRAEICFY	KCNH4	86	Q9UQ05
QVVRRAQDFVYHLHC	LHX3	101	Q9UBR4
ISRYLLSVCGFRFHH	NPIPB5	606	A8MRT5
GEHLYVLERLCVNGH	MICAL1	701	Q8TDZ2
LHGALEHYVNCLDLV	POLG2	186	Q9UHN1
CLHLASIHGYLGIVE	NFKBIA	186	P25963
HFYRTGHLHVLDELC	KCNS1	116	Q96KK3
RGNLAHCYSAEELVH	HOXA11	76	P31270
GRLNFCQSHVILHTY	OR52P1	166	Q8NH57
DYIGHSHQLFHICAV	PAQR6	251	Q6TCH4
QAFHYVCQRLGVSHI	HECTD4	196	Q9Y4D8
FCGRHFTKSYNLLIH	OSR2	176	Q8N2R0
LEYLHSQAHCIGFPE	NOC2L	531	Q9Y3T9
LYHCLLEHLQRIGGS	POF1B	271	Q8WVV4
VRHLIDNCAFRLYGH	PHKG2	346	P15735
HRLLHYCGSDFVFQA	ADAMTSL5	371	Q6ZMM2
EFLSHQLHEYCYRDG	PTF1A	51	Q7RTS3
ELLTFCIQHHTFYIR	PPP4R3C	516	Q6ZMV5
LVRSLCAKHGLHYVN	FADS2B	441	A8MWK0
RAHLDYCHGDVINHF	OR6V1	161	Q8N148
GRYFLLCHSSLLDHL	PARP14	476	Q460N5
CSVVDLINHYRHESL	PIK3R2	396	O00459
NQLSHEVLCHIFRYL	FBXO38	31	Q6PIJ6
VAYLECSARLHDNVH	RHOD	166	O00212
HCHAAAATYILEAGK	COMMD3	61	Q9UBI1
CVSHHDQLFRDEYAL	PIKFYVE	421	Q9Y2I7
FAPLVQYGCHSHLRF	FZD9	76	O00144
QYGCHSHLRFFLCSL	FZD9	81	O00144
AAVLLHFKGYSHCVD	EXOC5	216	O00471
IIFICGNLAGAYHKH	ADCY2	196	Q08462
LYAHLCRFLALCLGH	ESPL1	1596	Q14674
EHVVQACHRFIQASY	BCL6B	121	Q8N143
CYVHVAALVAEFLHR	DOCK11	1641	Q5JSL3
FLRIICSHEHYVTLN	DOCK7	1121	Q96N67
QCHEEGLESHLRSYV	DOCK9	901	Q9BZ29
HLCTSHYLDLFITGV	CACNA1G	1606	O43497
DQCHGLRELALNYHL	FBXL3	221	Q9UKT7
AHHYAATLCALEVRA	FBXL8	296	Q96CD0
VCLSRIYLAAHFPHQ	G6PC1	166	P35575
GRCYLRHFNELEHEL	ATG9A	336	Q7Z3C6
RVCEYVGTLEHNHFS	ARFGEF3	1016	Q5TH69
FFHRYLQTLHLQSCD	CCZ1	171	P86791
HFSIGNHDCYIKAVS	FAIM	141	Q9NVQ4
LLHFRDGCYHLETST	FSCN3	181	Q9NQT6
CEASNKHGHARALYV	CADM4	291	Q8NFZ8
FFHRYLQTLHLQSCD	CCZ1B	171	P86790
VLLYCDFHGHSRKNN	AGBL2	551	Q5U5Z8
SYHRLHALAADLGCL	CERS1	231	P27544
ALHQAYCHIAHSLGD	CEP162	291	Q5TB80
FICHVVGITYQHIDR	EIF3K	141	Q9UBQ5
RLLYAVNTHCHADHI	ETHE1	71	O95571
HYLELGAEIARTCHE	MAN1A1	496	P33908
GHYLELGAEIARTCH	MAN1A2	481	O60476
GLRHFTEYRIDIHAC	INSRR	776	P14616
HCRLVALDGHLYAIG	KLHDC7A	581	Q5VTJ3
AVCVDRVLYLFGGHH	KLHDC2	96	Q9Y2U9
FAEYARLCFQELGHH	KL	666	Q9UEF7
SGSLHEFLVNLHERY	CYP20A1	51	Q6UW02
LLTCHSAEYVGHLRA	HDAC6	536	Q9UBN7
YCRLQGEHQGSLIIH	PTK2B	351	Q14289
NHSILAFHYLHAGLC	CELSR3	2746	Q9NYQ7
AAEHTLLHRLFLCYQ	HELZ2	711	Q9BYK8
FYTAQIICGLEHLHQ	GRK1	296	Q15835
LDSSADLIRHVYFHC	HINFP	76	Q9BQA5
IYNHGCTGLFERHKL	DNAH10	3711	Q8IVF4
LRGNHECRHLTEYFT	PPP3CB	156	P16298
AQYACSLLGHALQRH	PEX11B	21	O96011
GLIDYNFHCFRKAIH	RRAGD	351	Q9NQL2
HRCAAQLASALEYIH	SBK2	161	P0C263
CIDRLHVYSSAAHFA	RYR2	501	Q92736
HTLRLYSAVCALGNH	RYR2	1656	Q92736
YSAVCALGNHRVAHA	RYR2	1661	Q92736
IRNVFHCEAHRILYV	SLFN13	616	Q68D06
LCLYDGFLTLVDLHH	MFSD13A	131	Q14CX5
RGHFLHNIYPCAFID	BVES	186	Q8NE79
LLRGNHECRHLTEYF	PPP3CA	146	Q08209
LQGVAYLHENCVVHR	MAP3K19	1171	Q56UN5
VNQHLCGSHLVEALY	INS-IGF2	26	F8WCM5
VCGKVFNAHYNLTRH	FEZF2	281	Q8TBJ5
HFVEIRCYIDNLHFS	LIFR	216	P42702
DASCHGHAYRLQSAI	PKD1	3691	P98161
ISRYLLSVCGFRFHH	NPIPB13	611	A6NJU9
TYAHLAAVACGLERF	NYNRIN	1351	Q9P2P1
SCRLYELLHGAGNHA	HCRT	46	O43612
CEHLDHALLYGLQDL	PLEKHM2	46	Q8IWE5
FALHIPYCRSRAIDH	OR2L13	161	Q8N349
HDGAFYRAVLALHQD	MTOR	1541	P42345
YICREILQGLAHLHA	NRK	156	Q7Z2Y5
KRNYSHHNGLDELTC	MTA3	576	Q9BTC8
HRQDYGAVFLCDHRF	RTEL1	701	Q9NZ71
KQYLELHASGRFHCS	RTP1	81	P59025
HVHVIGEDAACIAYI	CAMK2B	606	Q13554
HCLHGLRGIYSQLET	STK11IP	121	Q8N1F8
NGVIHSYELQFHVAC	USH2A	4856	O75445
QAYICAVQLDHGHAA	UTY	336	O14607
CLLADHTVHVLRYFF	ARHGAP11A	161	Q6P4F7
GHDLEFCLYGREEHL	SORT1	696	Q99523
AHLGHACSYVRFDII	CARS2	86	Q9HA77
YLHGLCASTSDLHRN	TMC3	821	Q7Z5M5
VRYFLHTGHLTIAGC	CARS1	391	P49589
CQYAHPGLALHTVRE	TATDN2	721	Q93075
EALYLLECGSIHLFH	TSEN54	116	Q7Z6J9
CQLLASLFGLYFHQH	TMEM161A	461	Q9NX61
LGFTNFIAHAIRHCY	SLC22A17	311	Q8WUG5
VNSLTGYGIHHCFAR	SLC22A23	436	A1A5C7
GYFLHHIIFACCTLI	SLC22A23	596	A1A5C7
FYHSAALLIGIHGCI	SLC27A2	266	O14975
LHCRSYGQDHLDTGL	SLC5A6	581	Q9Y289
RSVLRGCLEQLHHYA	SMG1	2631	Q96Q15
GCLEQLHHYATVALQ	SMG1	2636	Q96Q15
EAQHYCHVQRGFLAH	PKD1L3	46	Q7Z443
GCDVFHLRYAHHLLL	SIM2	271	Q14190
GLLCHHTSYLDQRVA	SIPA1L2	1596	Q9P2F8
LAFYICHEVHLAGFK	ST3GAL6	266	Q9Y274
GCSVLQRHSRDTHFY	SHLD1	156	Q8IYI0
IRNVFHCEAHRILYV	SLFN11	616	Q7Z7L1
CHHLRNTSDGVGYFR	TEKT3	271	Q9BXF9
ALCLHAGASRLAQHY	SH3TC1	911	Q8TE82
CVLAVAFAAHHYSQL	SSPN	136	Q14714
RCHHYTSDNELEGRL	PRAMEF1	241	O95521
YHAAALRGKCNISHF	RERE	236	Q9P2R6
NYLCHAVEHGFIQTL	SEMA3A	646	Q14563
AYDHFRSCLHALEQL	METTL22	351	Q9BUU2
FLLYATLHSGNHCRF	PRORP	481	O15091
ILHTDVVYLHCGQGF	SRBD1	561	Q8N5C6
LDHTFCVEHNAFGRI	SMURF1	551	Q9HCE7
HHVRRYVCAFLNSEG	SLFNL1	241	Q499Z3
GCQYLEENHFIHRDI	ALK	1236	Q9UM73
HLPQAQRYCEGHFSL	ALG10	41	Q5BKT4
SECAGRLLHTQYHAV	CIAO3	451	Q9H6Q4
LCQADLIYISHLHSD	CMAHP	81	Q9Y471
VYAHCKLLLADENGH	SLC25A12	501	O75746
LTRYEHFSSCLHQVL	CIP2A	271	Q8TCG1
LRHVLVDDAHGLLYC	CHST13	96	Q8NET6
VIFSCSNYFHVILHG	CHPT1	236	Q8WUD6
VVLGDHINTFLQHYC	C17orf64	86	Q86WR6
DCGKVFRHNSYLAIH	ZNF665	546	Q9H7R5
SHIYQLSQCLIERGH	PIGA	51	P37287
FHFYNPDVALVLHCR	SPG11	1901	Q96JI7
FLLRGNHECRHLTDY	PPP3CC	141	P48454
NICELHYTRDLGHDR	RNF213	416	Q63HN8
YHVHDLIGAQLVDCI	STK19	341	P49842
ALKSHIQGSHCEVFY	ZNF532	856	Q9HCE3
LYAVLVHTGFNCHAG	USP42	356	Q9H9J4
LCGHGATKYQALELH	ZFAT	436	Q9P243
ILHQRFHTGENLYEC	ZNF197	666	O14709
HECGKVFRHNSYLAT	ZNF160	316	Q9HCG1
HLIERYYHQLTEGCG	UBE3A	31	Q05086
IVHLEDHLFCQYLFR	UGT1A10	211	Q9HAW8
HGDQCFNVALAYHAL	TTC24	116	A2A3L6
RQAIEFACHQFYILH	UNC80	2251	Q8N2C7
DFYVSCRGHLFSRQH	ZFHX2	2156	Q9C0A1
HLAFDILRHNTGYCV	SLC16A5	226	O15375
YGQHCERSLEELLHY	RMND5B	21	Q96G75
CFSIYHGSHRESLDL	PLCH2	121	O75038
CFHQDSRAHLLLTDY	TMEM39A	201	Q9NV64
ATIGRTHLDIYDHCQ	TONSL	111	Q96HA7
LHEACNYGHLEIVRF	TONSL	566	Q96HA7
CLHLYSHLTDLEGAF	WDR97	526	A6NE52
LHNACSYGHYEVAEL	TNKS	721	O95271
VFAVGFLCHDLRSHS	TMEM214	491	Q6NUQ4
LQHQRFHTGEKLYEC	ZNF620	296	Q6ZNG0
LCGAQYRIHTHGVFR	WT1	281	P19544
GHTDYIHCLALRERS	THOC6	166	Q86W42
TVLLGLFCVHYFHRT	SRD5A2	81	P31213
VVGIFCILLAHDHYT	SGMS1	316	Q86VZ5
DGRACYGHLLHEVQK	STAB1	351	Q9NY15
DEAHCLRLDAIYHNI	ROS1	311	P08922
SRSLHGCYLEELHVL	SEMA5B	506	Q9P283
GHLYSALLADALCRH	MARS2	61	Q96GW9
LAYRVFHCTQYIRHG	TPH2	291	Q8IWU9
AVYAVAHALHSLLGC	TAS1R2	391	Q8TE23
ATFEELCHNYAHERL	MYO18B	961	Q8IUG5
SLELFCGHQEHYLTR	nan	581	Q3C1V9
LYANICFRHHETSGD	TNFSF11	216	O14788
GIFIRDVHNFCITYH	TMEM262	31	E9PQX1
CGKVFLESAALIHHY	ZNF264	376	O43296
EVLFACAEALHAHGY	ZSWIM8	771	A7E2V4
GSDFCHTSYLLEHQR	ZNF655	336	Q8N720
LFGHCIVLFITYNIH	YIPF3	226	Q9GZM5
ECGKAFRQYAHLTRH	ZFP82	286	Q8N141
CGKAFRHRSALIEHY	ZNF70	396	Q9UC06
VFHTNDFEGCHLYRV	VN1R5	216	Q7Z5H4
GKAFHCLSLYLIHER	ZNF69	226	Q9UC07
SFCYISALRIHQRVH	ZNF230	176	Q9UIE0
HLAGVLLHSLSEECY	TTC7A	286	Q9ULT0
YCSAFILHQRIHTGE	ZNF835	121	Q9Y2P0
KGFSCHAYLLVHRRI	ZNF74	451	Q16587
HSLQLKACFVHTGVY	TRAPPC8	1386	Q9Y2L5
DCGSREQLIAHVYQH	ZNF821	126	O75541
DAGECANYVRVLHHY	SEMA3E	111	O15041
LCDYSGYLRHDITRH	ZNF142	1261	P52746
RCVHELEFVDYVFHG	RAPGEFL1	441	Q9UHV5
HHALYVAFSSCIIRI	SEMA6D	496	Q8NFY4
VHYDCHLAAVRLARG	UBR4	4886	Q5T4S7
FCSRFGHHDIVKYLL	TNNI3K	241	Q59H18
SACYHGHIRLVQFLL	TNNI3K	346	Q59H18
HSAHREYIACVILGV	TMEM163	146	Q8TC26
AFSYCAAFIQHQRIH	ZNF79	341	Q15937
REINLLAYHGACHGA	WBP1	91	Q96G27
CYSAGVFHLHQGDIL	TNFSF13	211	O75888
EAVRYLHNCRIAHLD	TRIO	2901	O75962
LEKHYDCSVLGSQHF	TRIM6	336	Q9C030
GKSFCYISALHIHQR	ZNF222	151	Q9UK12
GKLDENHCRHQVAYL	MYO1G	611	B0I1T2