Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionsodium:bicarbonate symporter activity

SLC4A7 SLC4A8 SLC4A10

6.24e-076643GO:0008510
GeneOntologyMolecularFunctionmonoatomic cation:bicarbonate symporter activity

SLC4A7 SLC4A8 SLC4A10

8.78e-0613643GO:0140410
GeneOntologyMolecularFunctionsodium,bicarbonate:chloride antiporter activity

SLC4A8 SLC4A10

3.03e-053642GO:0140892
GeneOntologyMolecularFunctionsolute:monoatomic cation symporter activity

SLC4A7 SLC4A8 SLC5A6 SLC4A10 SLC45A1

3.98e-05119645GO:0015294
GeneOntologyMolecularFunctiontransporter activity

SLC4A7 SLC4A8 CLCN2 SLC38A9 SLC5A6 SLC4A10 PEX1 ATP13A5 NDUFA4 SLC45A1 TMEM41B SLC38A6 RHCE CHRNB4

4.61e-0512896414GO:0005215
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

SLC4A7 SLC4A8 SLC5A6 SLC4A10 ATP13A5 NDUFA4 SLC45A1

4.91e-05301647GO:0022853
GeneOntologyMolecularFunction1-phosphatidylinositol 4-kinase activity

PI4K2B PI4K2A

6.04e-054642GO:0004430
GeneOntologyMolecularFunctionsymporter activity

SLC4A7 SLC4A8 SLC5A6 SLC4A10 SLC45A1

1.19e-04150645GO:0015293
GeneOntologyMolecularFunctionmonoatomic anion transmembrane transporter activity

SLC4A7 SLC4A8 CLCN2 SLC5A6 SLC4A10

1.23e-04151645GO:0008509
GeneOntologyMolecularFunctionsolute:sodium symporter activity

SLC4A7 SLC4A8 SLC5A6 SLC4A10

1.33e-0481644GO:0015370
GeneOntologyMolecularFunctionbicarbonate transmembrane transporter activity

SLC4A7 SLC4A8 SLC4A10

1.46e-0432643GO:0015106
GeneOntologyMolecularFunctionsolute:inorganic anion antiporter activity

SLC4A7 SLC4A8 SLC4A10

1.46e-0432643GO:0005452
GeneOntologyMolecularFunctioninorganic anion transmembrane transporter activity

SLC4A7 SLC4A8 CLCN2 SLC5A6 SLC4A10

2.20e-04171645GO:0015103
GeneOntologyMolecularFunctionlipid kinase activity

PI4K2B PI4K2A AGK

3.07e-0441643GO:0001727
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLC4A7 SLC4A8 CLCN2 SLC38A9 SLC5A6 SLC4A10 ATP13A5 NDUFA4 SLC45A1 SLC38A6 RHCE CHRNB4

3.23e-0411806412GO:0022857
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLC4A7 SLC4A8 SLC38A9 SLC5A6 SLC4A10 SLC38A6

3.48e-04293646GO:0008514
GeneOntologyMolecularFunctionarginine binding

SLC38A9 NOS2

3.59e-049642GO:0034618
GeneOntologyMolecularFunctionL-glutamine transmembrane transporter activity

SLC38A9 SLC38A6

3.59e-049642GO:0015186
GeneOntologyMolecularFunctionchloride:bicarbonate antiporter activity

SLC4A8 SLC4A10

7.71e-0413642GO:0140900
GeneOntologyMolecularFunctionbicarbonate:monoatomic anion antiporter activity

SLC4A8 SLC4A10

7.71e-0413642GO:0140829
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC4A7 SLC4A8 SLC5A6 SLC4A10 ATP13A5 NDUFA4 SLC45A1

8.15e-04477647GO:0022804
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

SLC4A7 SLC4A8 CLCN2 SLC5A6 SLC4A10 ATP13A5 NDUFA4 SLC45A1 CHRNB4

9.13e-04793649GO:0015075
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

SLC4A7 SLC4A8 SLC5A6 SLC4A10 ATP13A5 NDUFA4 SLC45A1 CHRNB4

1.23e-03664648GO:0008324
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC4A7 SLC4A8 SLC5A6 SLC4A10

2.21e-03171644GO:0015081
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC4A7 SLC4A8 SLC5A6 SLC4A10 SLC45A1

2.58e-03296645GO:0015291
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

SLC4A7 SLC4A8 CLCN2 SLC5A6 SLC4A10 NDUFA4 SLC45A1 RHCE

2.81e-03758648GO:0015318
GeneOntologyMolecularFunctionphosphatidylinositol kinase activity

PI4K2B PI4K2A

3.13e-0326642GO:0052742
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

SLC4A7 SLC4A8 SLC5A6 SLC4A10 NDUFA4 SLC45A1 RHCE

3.84e-03627647GO:0022890
DomainANION_EXCHANGER_2

SLC4A7 SLC4A8 SLC4A10

1.27e-067633PS00220
DomainANION_EXCHANGER_1

SLC4A7 SLC4A8 SLC4A10

1.27e-067633PS00219
DomainBand3_cytoplasmic_dom

SLC4A7 SLC4A8 SLC4A10

3.03e-069633IPR013769
DomainBand_3_cyto

SLC4A7 SLC4A8 SLC4A10

3.03e-069633PF07565
Domain-

SLC4A7 SLC4A8 SLC4A10

3.03e-0696333.40.1100.10
DomainHCO3_cotransp

SLC4A7 SLC4A8 SLC4A10

4.32e-0610633PF00955
DomainHCO3_transpt_C

SLC4A7 SLC4A8 SLC4A10

4.32e-0610633IPR011531
DomainPTrfase/Anion_transptr

SLC4A7 SLC4A8 SLC4A10

4.32e-0610633IPR016152
DomainHCO3_transpt_euk

SLC4A7 SLC4A8 SLC4A10

4.32e-0610633IPR003020
DomainAnion_exchange

SLC4A7 SLC4A10

1.11e-045632IPR001717
DomainNa/HCO3_transpt

SLC4A8 SLC4A10

1.11e-045632IPR003024
DomainATPase_AAA_CS

PEX1 PSMC2 FIGNL1

1.26e-0429633IPR003960
DomainAAA

PEX1 PSMC2 FIGNL1

2.03e-0434633PS00674
DomainAAA

PEX1 PSMC2 FIGNL1

7.18e-0452633PF00004
DomainATPase_AAA_core

PEX1 PSMC2 FIGNL1

8.03e-0454633IPR003959
DomainAAA+_ATPase

DNAH10 PEX1 PSMC2 FIGNL1

1.42e-03144634IPR003593
DomainAAA

DNAH10 PEX1 PSMC2 FIGNL1

1.42e-03144634SM00382
DomainAa_trans

SLC38A9 SLC38A6

1.47e-0317632PF01490
DomainAA_transpt_TM

SLC38A9 SLC38A6

1.47e-0317632IPR013057
DomainPI3/4_kinase_cat_dom

PI4K2B PI4K2A

1.65e-0318632IPR000403
DomainPI3_PI4_kinase

PI4K2B PI4K2A

1.65e-0318632PF00454
DomainPI3_4_KINASE_3

PI4K2B PI4K2A

1.65e-0318632PS50290
DomainPI3_4_KINASE_1

PI4K2B PI4K2A

1.65e-0318632PS00915
DomainPI3_4_KINASE_2

PI4K2B PI4K2A

1.65e-0318632PS00916
DomainEGF_LAM_2

NTN3 LAMA4

4.58e-0330632PS50027
DomainEGF_LAM_1

NTN3 LAMA4

4.58e-0330632PS01248
DomainLaminin_EGF

NTN3 LAMA4

6.20e-0335632PF00053
DomainEGF_Lam

NTN3 LAMA4

6.20e-0335632SM00180
DomainLaminin_EGF

NTN3 LAMA4

7.28e-0338632IPR002049
PathwayREACTOME_BICARBONATE_TRANSPORTERS

SLC4A7 SLC4A8 SLC4A10

5.91e-0610533M27335
PathwayREACTOME_BICARBONATE_TRANSPORTERS

SLC4A7 SLC4A8 SLC4A10

5.91e-0610533MM15073
Pubmed

Immunocytochemical identification of electroneutral Na⁺-coupled HCO₃⁻ transporters in freshly dissociated mouse medullary raphé neurons.

SLC4A7 SLC4A8 SLC4A10

6.81e-08567323500099
Pubmed

Some human KIR haplotypes contain two KIR2DL5 genes: KIR2DL5A and KIR2DL5B.

KIR2DL5B KIR2DL5A

3.66e-06267212185535
Pubmed

K+-Driven Cl-/HCO3- Exchange Mediated by Slc4a8 and Slc4a10.

SLC4A8 SLC4A10

3.66e-06267238674160
Pubmed

Gene structure and promoter variation of expressed and nonexpressed variants of the KIR2DL5 gene.

KIR2DL5B KIR2DL5A

3.66e-06267211086080
Pubmed

Association of KIR2DL5B gene with celiac disease supports the susceptibility locus on 19q13.4.

KIR2DL5B KIR2DL5A

3.66e-06267217215859
Pubmed

Chronic continuous hypoxia decreases the expression of SLC4A7 (NBCn1) and SLC4A10 (NCBE) in mouse brain.

SLC4A7 SLC4A10

3.66e-06267217928512
Pubmed

The high-resolution crystal structure of phosphatidylinositol 4-kinase IIβ and the crystal structure of phosphatidylinositol 4-kinase IIα containing a nucleoside analogue provide a structural basis for isoform-specific inhibitor design.

PI4K2B PI4K2A

3.66e-06267226143926
Pubmed

Acylglycerol kinase promotes paclitaxel resistance in nasopharyngeal carcinoma cells by regulating FOXM1 via the JAK2/STAT3 pathway.

FOXM1 AGK

3.66e-06267234116927
Pubmed

Type II PI4-kinases control Weibel-Palade body biogenesis and von Willebrand factor structure in human endothelial cells.

PI4K2B PI4K2A

1.10e-05367227068535
Pubmed

Nos2 inactivation promotes the development of medulloblastoma in Ptch1(+/-) mice by deregulation of Gap43-dependent granule cell precursor migration.

PTCH1 NOS2

1.10e-05367222438824
Pubmed

Regulation of the human NBC3 Na+/HCO3- cotransporter by carbonic anhydrase II and PKA.

SLC4A7 SLC4A8

1.10e-05367214736710
Pubmed

The FOXM1 inhibitor RCM-1 suppresses goblet cell metaplasia and prevents IL-13 and STAT6 signaling in allergen-exposed mice.

FOXM1 STAT6

1.10e-05367228420758
Pubmed

Type II phosphatidylinositol 4-kinase beta is a cytosolic and peripheral membrane protein that is recruited to the plasma membrane and activated by Rac-GTP.

PI4K2B PI4K2A

1.10e-05367212324459
Pubmed

Promoter variants of KIR2DL5 add to diversity and may impact gene expression.

KIR2DL5B KIR2DL5A

1.10e-05367218461314
Pubmed

The COOH termini of NBC3 and the 56-kDa H+-ATPase subunit are PDZ motifs involved in their interaction.

SLC4A7 SLC4A8

1.10e-05367212444018
Pubmed

Characterization of type II phosphatidylinositol 4-kinase isoforms reveals association of the enzymes with endosomal vesicular compartments.

PI4K2B PI4K2A

1.10e-05367211923287
Pubmed

KIR2DL5, a novel killer-cell receptor with a D0-D2 configuration of Ig-like domains.

KIR2DL5B KIR2DL5A

2.19e-05467210820258
Pubmed

Distinct plasma-membrane PtdIns(4)P and PtdIns(4,5)P2 dynamics in secretagogue-stimulated beta-cells.

PI4K2B PI4K2A

2.19e-05467220375060
Pubmed

A SCL4A10 gene product maps selectively to the basolateral plasma membrane of choroid plexus epithelial cells.

SLC4A7 SLC4A10

2.19e-05467214592810
Pubmed

Killer-cell immunoglobulin-like receptors (KIR) in severe A (H1N1) 2009 influenza infections.

KIR2DL5B KIR2DL5A

2.19e-05467222652695
Pubmed

The cystic fibrosis transmembrane conductance regulator interacts with and regulates the activity of the HCO3- salvage transporter human Na+-HCO3- cotransport isoform 3.

SLC4A7 SLC4A8

2.19e-05467212403779
Pubmed

Hypoxic inhibition of JMJD3 reduces H3K27me3 demethylation and induction of the STAT6 target gene CCL18.

SPINT2 STAT6

2.19e-05467227737800
Pubmed

Molecular expression of SLC4-derived Na+-dependent anion transporters in selected human tissues.

SLC4A7 SLC4A8

2.19e-05467217715183
Pubmed

Investigation of killer cell immunoglobulin-like receptor (KIR) gene diversity: KIR2DL2, KIR2DL5 and KIR2DS5.

KIR2DL5B KIR2DL5A

2.19e-05467218498296
Pubmed

Stabilization of phosphatidylinositol 4-kinase type IIbeta by interaction with Hsp90.

PI4K2B PI4K2A

3.64e-05567221330372
Pubmed

Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

HAUS6 FLYWCH1 MAGI3 EPG5

4.46e-0510167410997877
Pubmed

Early Hearing Loss upon Disruption of Slc4a10 in C57BL/6 Mice.

SLC4A7 SLC4A10

5.46e-05667231001720
Pubmed

Type I interferon restricts type 2 immunopathology through the regulation of group 2 innate lymphoid cells.

NOS2 STAT6

7.63e-05767226595887
Pubmed

Mutations in Traf3ip1 reveal defects in ciliogenesis, embryonic development, and altered cell size regulation.

PTCH1 STAT6

1.63e-041067221945076
Pubmed

Scaffolding protein SPIDR/KIAA0146 connects the Bloom syndrome helicase with homologous recombination repair.

RMI1 FIGNL1

1.63e-041067223509288
Pubmed

The DNA sequence of human chromosome 7.

ERVFC1-1 PEX1 PSMC2 AGK FIGNL1 GLCCI1

2.09e-0444167612853948
Pubmed

Severe neurologic impairment in mice with targeted disruption of the electrogenic sodium bicarbonate cotransporter NBCe2 (Slc4a5 gene).

SLC4A7 SLC4A10

2.38e-041267221705333
Pubmed

Different KIRs confer susceptibility and protection to adults with latent autoimmune diabetes in Latvian and Asian Indian populations.

KIR2DL5B KIR2DL5A

2.81e-041367219120281
Pubmed

Th2 and eosinophil responses suppress inflammatory arthritis.

NOS2 STAT6

3.28e-041467227273006
Pubmed

Evolutionary origin of amino acid transporter families SLC32, SLC36 and SLC38 and physiological, pathological and therapeutic aspects.

SLC38A9 SLC38A6

3.78e-041567223506890
Pubmed

Identification and analysis of genes from the mouse otic vesicle and their association with developmental subprocesses through in situ hybridization.

DENND2A PTCH1 GLCCI1

4.02e-047467315031102
Pubmed

[Polymorphism of killer cell immunoglobulin-like receptors gene family in Zhejiang Han population].

KIR2DL5B KIR2DL5A

4.31e-041667216403292
Pubmed

AP-SWATH Reveals Direct Involvement of VCP/p97 in Integrated Stress Response Signaling Through Facilitating CReP/PPP1R15B Degradation.

DERL1 PEX1 FIGNL1

4.34e-047667329599191
Pubmed

Emx2 stimulates odorant receptor gene expression.

OR6F1 CYP2G1P

4.88e-041767218854508
Pubmed

[Analysis of natural killer cell immunoglobulin-like receptor genes in Chinese].

KIR2DL5B KIR2DL5A

4.88e-041767219218127
Pubmed

Association of KIR2DS1 and KIR2DS3 with fatal outcome in Ebola virus infection.

KIR2DL5B KIR2DL5A

4.88e-041767220878400
Pubmed

Killer cell immunoglobulin-like receptor gene diversity in the Tibetan ethnic minority group of China.

KIR2DL5B KIR2DL5A

4.88e-041767220650299
Pubmed

Killer cell immunoglobulin-like receptor gene polymorphisms in patients with leukemia: possible association with susceptibility to the disease.

KIR2DL5B KIR2DL5A

4.88e-041767219450876
Pubmed

Distribution of killer-cell immunoglobulin-like receptor genes in Eastern mainland Chinese Han and Taiwanese Han populations.

KIR2DL5B KIR2DL5A

4.88e-041767219761533
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

TICRR ADRA1D IARS1 ALDH16A1 PRICKLE2 MAGI3 CHRNB4

5.34e-0473667729676528
Pubmed

Signatures of natural selection and coevolution between killer cell immunoglobulin-like receptors (KIR) and HLA class I genes.

KIR2DL5B KIR2DL5A

5.48e-041867220200544
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

IQSEC3 PRICKLE2 SLC4A10 BCAN GLCCI1

5.59e-0434767517114649
Pubmed

Human chromosome 7: DNA sequence and biology.

PEX1 PSMC2 AGK NDUFA4 FIGNL1 GLCCI1

5.87e-0453667612690205
Pubmed

Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.

DNAH10 TMEM132D PRICKLE2 PTPRT

6.01e-0419967423382691
Pubmed

The forkhead box m1 transcription factor is essential for embryonic development of pulmonary vasculature.

FOXM1 LAMA4

6.12e-041967215817462
Pubmed

Fraction of exhaled nitric oxide values in childhood are associated with 17q11.2-q12 and 17q12-q21 variants.

NOS2 PTPRT

6.12e-041967224315451
Pubmed

HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.

FOXM1 EPPK1 IARS1 PRICKLE2 PEX1 PSMC2 TMEM41B

6.16e-0475467735906200
Pubmed

Compound KIR-HLA genotype analyses in the Iranian population by a novel PCR-SSP assay.

KIR2DL5B KIR2DL5A

6.79e-042067220193031
Pubmed

HLA and KIR frequencies in Sicilian Centenarians.

KIR2DL5B KIR2DL5A

6.79e-042067220426625
Pubmed

Regulatory pathway analysis by high-throughput in situ hybridization.

BCAN PTPRT CHRNB4

7.35e-049167317953485
Pubmed

A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.

HAUS6 ALDH16A1 PI4K2A PSMC2 AGK CLUH

7.37e-0456067635241646
Pubmed

Distribution of KIR genes in the population of unrelated individuals homozygous for ancestral haplotype AH8.1 (HLA-A1B8DR3).

KIR2DL5B KIR2DL5A

8.24e-042267220492596
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

HAUS6 SPINT2 TMTC4 PI4K2A SLC4A10 PSMC2 SLC45A1 STAT6

9.69e-04106167833845483
Pubmed

Extracellular HIV-1 viral protein R affects astrocytic glyceraldehyde 3-phosphate dehydrogenase activity and neuronal survival.

FOXM1 NOS2

9.82e-042467223728617
Pubmed

Myocardium defects and ventricular hypoplasia in mice homozygous null for the Forkhead Box M1 transcription factor.

FOXM1 LAMA4

9.82e-042467217366632
Pubmed

Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex.

EPPK1 SLC4A7 IARS1 PSMC2 CLUH

1.04e-0339967537536630
Pubmed

Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss.

SLC4A7 CLCN2 PEX1 EPG5

1.08e-0323367432290105
Pubmed

Forkhead box F2 regulation of platelet-derived growth factor and myocardin/serum response factor signaling is essential for intestinal development.

FOXM1 PTCH1

1.24e-032767225631042
Pubmed

Stasimon/Tmem41b localizes to mitochondria-associated ER membranes and is essential for mouse embryonic development.

SLC5A6 PSMC2 TMEM41B

1.38e-0311367330352685
Pubmed

LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells.

HAUS6 EPPK1 SPINT2 IARS1 SLC4A10 PEX1

1.45e-0363967623443559
Pubmed

Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.

EPPK1 PRICKLE2 AGK MAGI3 NDUFA4

1.45e-0343067532581705
Pubmed

A genome-wide association study of behavioral disinhibition.

TMEM132D MROH7

1.54e-033067223942779
Pubmed

FOXF1 transcription factor promotes lung morphogenesis by inducing cellular proliferation in fetal lung mesenchyme.

FOXM1 PTCH1

1.64e-033167230153454
Pubmed

UM171 Preserves Epigenetic Marks that Are Reduced in Ex Vivo Culture of Human HSCs via Potentiation of the CLR3-KBTBD4 Complex.

SLC4A7 IARS1 ALDH16A1 AGK

1.78e-0326767433417871
Cytoband1q44

OR6F1 OR2L5 OR2L13

5.73e-041106731q44
Cytoband7p21.3

NDUFA4 GLCCI1

7.74e-04286727p21.3
CytobandEnsembl 112 genes in cytogenetic band chr1q44

OR6F1 OR2L5 OR2L13

8.90e-04128673chr1q44
GeneFamilySolute carriers

SLC4A7 SLC4A8 SLC38A9 SLC5A6 SLC4A10 SLC45A1 SLC38A6

5.78e-05395467752
GeneFamilyAAA ATPases

PEX1 PSMC2 FIGNL1

3.30e-0453463413
GeneFamilyCD molecules|Killer cell immunoglobulin like receptors

KIR2DL5B KIR2DL5A

9.44e-0418462620
ToppCellLPS-antiTNF-Unknown-Endothelial-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TICRR ADRA1D SLC4A8 DNAH10

3.92e-0513264402491930097b75aaeedab9e8200711b0dc610944
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Tubular|TCGA-Stomach / Sample_Type by Project: Shred V9

TICRR HROB CLCN2 FIGNL1

4.67e-0513864493497c0a5d5e54006653b2dedc7a7041e1a613e6
ToppCellBAL-Control-cDC_4|Control / Compartment, Disease Groups and Clusters

HROB SLC4A7 MROH7 RHCE

5.66e-051456443b2a2965dc18abd39d5ed70c0fcad0210e7f12c8
ToppCellCOVID-19-Epithelial_cells-Airway_mucous|COVID-19 / group, cell type (main and fine annotations)

DNAH10 MUC16 RSPH9 PTPRT

6.62e-051516448216462e723fec2797387929dde095370947e10a
ToppCellDividing_Macrophages-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

FOXM1 TICRR HROB SLC45A1

6.80e-05152644e39cfc346b35235546b303e7d73e4d9d7120a5fb
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

TMEM132D PRICKLE2 MAGI3 GLCCI1

9.56e-05166644c20479fe7a4306320d7f26e78bf956225f00f35a
ToppCellfacs-Heart-RV-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IQSEC3 EPPK1 SLC4A8 SPINT2

1.17e-04175644d8e385320f554d974538b7cdc4f8e4767f1455f2
ToppCellfacs-Heart-RV-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IQSEC3 EPPK1 SLC4A8 SPINT2

1.17e-04175644cf15465855602ba135752c18755e3e058dbd42ec
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Endothelial-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLCN2 DNAH10 PTCH1 EPG5

1.39e-04183644919c9861073d12fd12aecd7469b1478b13838c43
ToppCell343B-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

THOP1 DERL1 SLC4A10 EPG5

1.42e-041846442c2125b8030af83f7a6d59a7102d4de8e0ac1988
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Adult / Lineage, Cell type, age group and donor

PRICKLE2 MAGI3 TMEM41B GLCCI1

1.45e-04185644673f0c688ae6984bc8027df2da335787924f4137
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Children_(3_yrs) / Lineage, Cell type, age group and donor

TMEM132D PRICKLE2 MAGI3 GLCCI1

1.45e-0418564498b8ee42b89d97e4c9db01740e0c193503c68f2c
ToppCellCOVID-19-Epithelial_cells-Airway_ciliated|COVID-19 / group, cell type (main and fine annotations)

DNAH10 MUC16 RSPH9 PTPRT

1.45e-0418564418a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCellfacs-Skin-Telogen-3m-Epithelial-actively_dividing_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXM1 TICRR TMPRSS3 FIGNL1

1.48e-041866449feef5936985e936b3d88f9d1bb012abb6468570
ToppCellfacs-Skin-Telogen-3m-Epithelial-keratinocyte_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXM1 TICRR TMPRSS3 FIGNL1

1.48e-0418664489f5b06bc56674af304912d481ac697c7c870904
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DNAH10 MUC16 RSPH9 PTPRT

1.64e-04191644e417bf491f8b8d7838a61f7f4f6b1740ba97aa3f
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DNAH10 MUC16 RSPH9 PTPRT

1.64e-041916449d31c8424d35bdc0c27188b68bfd0f731af3600b
ToppCellnucseq-Epithelial-Epithelial_Airway|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DNAH10 MUC16 RSPH9 PTPRT

1.64e-041916441c528f72c9ef3ef3a850b05e4a9715190832270c
ToppCellNS-critical-d_16-33-Epithelial-Secretory-diff|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SPINT2 MUC16 ATP13A5 NOS2

1.67e-0419264402b11233b4da2d85b96498b3c6e22e3a31b3d049
ToppCellCOPD-Epithelial-Ciliated|World / Disease state, Lineage and Cell class

DNAH10 MUC16 RSPH9 PTPRT

1.67e-04192644eab1105cd1a98cfcd3d74dc5c9b89e1799bba59e
ToppCellfacs-Marrow-B-cells-18m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THOP1 TMPRSS3 GLCCI1 RSPH9

1.71e-041936449c2f58b4c89dc084a1a6e53952ea793e87a96660
ToppCellfacs-Marrow-B-cells-18m-Lymphocytic-late_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THOP1 TMPRSS3 GLCCI1 RSPH9

1.71e-04193644db881cc129b45031fd84d052768cef53508de196
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FOXM1 TICRR HAUS6 MPV17L2

1.71e-04193644e45ce9cf8421512b57f157c24b64793b47b4ba4b
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FOXM1 TICRR HROB VSIG4

1.71e-04193644444de545117dae8ab24a22880583ac2f0b2d6eac
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_OPC|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

LAMA4 BCAN GLCCI1 PTPRT

1.74e-04194644920955e775617d6156c5ee8b90d2cecd01a70e12
ToppCellCOVID-19-Epithelial-Ciliated_cells|COVID-19 / Condition, Lineage and Cell class

DNAH10 MUC16 RSPH9 PTPRT

1.74e-0419464443be5fbd51dd58839cb03ca3ddd05a458e1ddb74
ToppCellIPF-Multiplet-Multiplet|IPF / Disease state, Lineage and Cell class

DNAH10 PRICKLE2 RSPH9 PTPRT

1.77e-04195644fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCellIPF-Multiplet-Multiplet|World / Disease state, Lineage and Cell class

DNAH10 PRICKLE2 RSPH9 PTPRT

1.77e-0419564421dbdc803c6947024dc2416e9e21c2ef0af9bc31
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXM1 TMPRSS3 FIGNL1 RSPH9

1.77e-04195644294c74336fafc1bad237d851efb4a487475078eb
ToppCellIPF-Multiplet|IPF / Disease state, Lineage and Cell class

DNAH10 PRICKLE2 RSPH9 PTPRT

1.77e-04195644eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-late_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXM1 TMPRSS3 FIGNL1 RSPH9

1.77e-041956445749ea833be84e262e3d0a4fe1a9a373f0ef545f
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Club|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PI4K2B PRICKLE2 MAGI3 GLCCI1

1.81e-04196644ed76eeb37400ca154feae9b7ebaddb6c434f8b81
ToppCellCOVID-19-Epithelial-Ciliated_cells|Epithelial / Condition, Lineage and Cell class

DNAH10 MUC16 RSPH9 PTPRT

1.81e-04196644de7aa31354b019d7321a8ef965d59ce2e8b89276
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_airway_secretory-Secretory_Club|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

PI4K2B SPINT2 MAGI3 GLCCI1

1.81e-04196644d5f9168001e60bafec17fe6c702e68f5528edc20
ToppCellIPF-Epithelial|IPF / Disease state, Lineage and Cell class

DNAH10 PRICKLE2 RSPH9 PTPRT

1.81e-0419664487d9881cfec461a5d89b688a83749b618c519485
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DENND2A LAMA4 BCAN PTCH1

1.84e-0419764444673c38384453207871d3fd8e8ba9093cc06bc5
ToppCellBAL-Mild-Epithelial-Epithelial|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DNAH10 MUC16 RSPH9 PTPRT

1.92e-041996441ee4010d8557564e25e8ee00b914c2dfd9037838
ToppCellBAL-Mild-Epithelial-Epithelial|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

DNAH10 MUC16 RSPH9 PTPRT

1.92e-041996441df69c0cb5f759f6a2152521842506a75bb95cae
ToppCellMild-Epithelial-Epithelial-|Mild / Condition, Lineage, Cell class and cell subclass

DNAH10 MUC16 RSPH9 PTPRT

1.92e-0419964481115bbd2c10bfdd38376d2075f03a59c31870d2
ToppCellBAL-Mild-Epithelial|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DNAH10 MUC16 RSPH9 PTPRT

1.92e-0419964474087b4b5e567310fc4ac58fb267ff651a180680
ToppCellBAL-Mild-Epithelial|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

DNAH10 MUC16 RSPH9 PTPRT

1.92e-0419964400b5ce099c50a5e1786ce2b3a06ee0931a8205a4
ToppCellMild-Epithelial|Mild / Condition, Lineage, Cell class and cell subclass

DNAH10 MUC16 RSPH9 PTPRT

1.92e-04199644ec5fff80e2a8a94fbaf1fdcc6d45c8d7c6252e18
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.6.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IQSEC3 HAUS6 MPV17L2 VSIG4

1.92e-04199644fde8e3ba19d19069a4d3b8db55bfe6220cf634d5
ToppCellMild-Epithelial-Epithelial|Mild / Condition, Lineage, Cell class and cell subclass

DNAH10 MUC16 RSPH9 PTPRT

1.92e-0419964491308b255783ad4029e5575028c18d7550832c51
ToppCellMild_COVID-19-Epithelial|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）

DNAH10 MUC16 RSPH9 PTPRT

1.92e-0419964472689bda7476930887ae007682fcab27f956f050
ToppCellMacroglial-Polydendrocytes-PDGFRA-|Macroglial / cells hierarchy compared to all cells using T-Statistic

TMEM132D SLC4A10 BCAN PTPRT

1.95e-04200644f17b5a54e8f9eba9dcd0808ba4e8d275ac41bce2
ToppCellMacroglial-Polydendrocytes-PDGFRA--|Macroglial / cells hierarchy compared to all cells using T-Statistic

TMEM132D SLC4A10 BCAN PTPRT

1.95e-04200644cc3409518f8b436ea92deb955e81114b3f410ff7
ToppCellMacroglial-Polydendrocytes-PDGFRA|Macroglial / cells hierarchy compared to all cells using T-Statistic

TMEM132D SLC4A10 BCAN PTPRT

1.95e-04200644c24a3099e3d96d8b72f6d05286bb355d661a0377
ToppCellMacroglial-Polydendrocytes-PDGFRA---|Macroglial / cells hierarchy compared to all cells using T-Statistic

TMEM132D SLC4A10 BCAN PTPRT

1.95e-042006444fc3de4bff7ed2bf40b38462c4b4e9b87af6a4ca
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar-Dividing_AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FOXM1 RMI1 TICRR HROB

1.95e-04200644af3dc76b4507bf4edd265169f5dfbbb8a19eb394
ToppCellMacroglial-Polydendrocytes-PDGFRA----L1-6|Macroglial / cells hierarchy compared to all cells using T-Statistic

TMEM132D SLC4A10 BCAN PTPRT

1.95e-04200644310cd53db1c137f6af74e6ae682221d7ac27310c
ToppCellMacroglial-Polydendrocytes|Macroglial / cells hierarchy compared to all cells using T-Statistic

TMEM132D SLC4A10 BCAN PTPRT

1.95e-04200644961858738ce35db8760c8c2e136f8369bc444ccf
Diseaseanemia (implicated_via_orthology)

SLC4A7 SLC4A8 SLC4A10

3.76e-0615613DOID:2355 (implicated_via_orthology)
Diseasesensory peripheral neuropathy, remission

FOXM1 PTPRT

1.03e-0323612EFO_0009785, MONDO_0002321
Diseaselung squamous cell carcinoma (is_implicated_in)

PTCH1 CHRNB4

1.13e-0324612DOID:3907 (is_implicated_in)
Diseasepancreatic cancer (is_marker_for)

MUC16 PTCH1 NOS2

1.21e-03101613DOID:1793 (is_marker_for)
DiseasePrecancerous Conditions

FOXM1 TMEM132D PRICKLE2

1.55e-03110613C0032927
DiseaseCondition, Preneoplastic

FOXM1 TMEM132D PRICKLE2

1.55e-03110613C0282313
DiseaseDrug-Induced Stevens Johnson Syndrome

DERL1 NOS2

1.65e-0329612C1274933
DiseaseToxic Epidermal Necrolysis

DERL1 NOS2

1.65e-0329612C0014518
DiseaseMycoplasma-Induced Stevens-Johnson Syndrome

DERL1 NOS2

1.65e-0329612C3658301
DiseaseStevens-Johnson Syndrome Toxic Epidermal Necrolysis Spectrum

DERL1 NOS2

1.65e-0329612C3658302
Diseaseamyotrophic lateral sclerosis (implicated_via_orthology)

ATP13A5 EPG5

1.76e-0330612DOID:332 (implicated_via_orthology)
DiseaseStevens-Johnson Syndrome

DERL1 NOS2

1.76e-0330612C0038325
Diseasemigraine disorder, glucose measurement

RMI1 SLC45A1

1.88e-0331612EFO_0004468, MONDO_0005277
Diseasesexual dimorphism measurement

FOXM1 HROB EPPK1 DNAH10 SLC38A9 ETFDH PEX1 PTCH1

1.92e-031106618EFO_0021796

Protein segments in the cluster

PeptideGeneStartEntry
VLGTVGLFLPPLFQT

CHRNB4

471

P30926
PTPGIQKVGISLFFT

EPG5

1661

Q9HCE0
EATFSKIPIGFIPLG

AGK

141

Q53H12
LVPGDILILPGKFSL

ATP13A5

281

Q4VNC0
MGVIGLILPPTFSFL

ALDH16A1

166

Q8IZ83
TGSAFCPVKLLGPLL

GLCCI1

456

Q86VQ1
CIFGELLTQKPLFPG

CDK11B

626

P21127
ASIKVGQFPLGFPIS

MROH7

381

Q68CQ1
NPLVIVVTGLFGKPS

KIR2DL5A

111

Q8N109
VSAGFLLSQLPILKP

NOS2

891

P35228
LPGVKTLFLFPNQTG

BCAN

326

Q96GW7
LLGPLFKNSSVGPLY

MUC16

13046

Q8WXI7
GLLKPLFKSTSVGPL

MUC16

13201

Q8WXI7
IFTGLRGPPKGILLF

FIGNL1

426

Q6PIW4
LGIILLGPFLQEFFP

MINDY3

356

Q9H8M7
LFPASGLRGFPNVLK

MPV17L2

86

Q567V2
LVTIPLIKGPKGFGF

MAGI3

576

Q5TCQ9
PIAFLGLKFSSLGPA

ERVFC1-1

101

P60608
GPEFLKTPLGGSFLV

FLYWCH1

506

Q4VC44
NPLVIVVTGLFGKPS

KIR2DL5B

111

Q8NHK3
FILLGLFPPSKIGLF

OR2L5

11

Q8NG80
SKFPTFLLTGIPGLE

OR51F1

16

A6NGY5
VLKFGPVDSTLGFLP

NUS1

241

Q96E22
PLVGKLGLISPAYLF

DERL1

26

Q9BUN8
PGSVLLLKQIGVFSP

HROB

541

Q8N3J3
PDKGIQFLISRGFIP

IQSEC3

666

Q9UPP2
GLLGFVRQVKFLNPP

PTPRT

1061

O14522
IGLPPKVGSFQLFVE

PI4K2A

251

Q9BTU6
RIGLPPKIGSFQLFV

PI4K2B

246

Q8TCG2
APLNVTLTVPLGKAF

NTN3

101

O00634
SLLGRPFLPKQGQIF

PRICKLE2

291

Q7Z3G6
FQSIPKLTFPGGLLI

ETFDH

371

Q16134
PFPALGKTILVKNFL

DENND2A

706

Q9ULE3
LPLLGFFIQTLDPKL

C1orf112

631

Q9NSG2
FGEGFSPLLPVQTIK

FOXM1

446

Q08050
VVGSLFLSPGGPKFI

HAUS6

111

Q7Z4H7
LTTDPTKGFPIGILQ

DNAH10

3966

Q8IVF4
FISPILGFLLQPLLG

SLC45A1

161

Q9Y2W3
VGLLLPLLNFKSPSF

SLC38A9

296

Q8NBW4
FILPFLKLSSLGGVN

PEX1

546

O43933
KTLPQDFLLLGFPGS

OR6F1

6

Q8NGZ6
FKLPTSLNLPGFVGC

LAMA4

991

Q16363
FILLGLLPPNQTGIF

OR2L13

11

Q8N349
FVNLGIEPPKGVLLF

PSMC2

201

P35998
VAIIPRGALFKTPFG

RSPH9

151

Q9H1X1
RFLFLLLGPAGKAPQ

SLC4A7

466

Q9Y6M7
SINGQLFKPLGPIII

TMEM132D

1011

Q14C87
LPPGTKILIYGNISF

RMI1

161

Q9H9A7
KGLPGLPGLFIACLF

SLC5A6

346

Q9Y289
APGSGLALLPLKITF

EPPK1

221

P58107
KHPSLIPLFVFIGTG

NDUFA4

11

O00483
NGLVLLPVLLSFFGP

PTCH1

1166

Q13635
VGIVFPLALLPKIGF

SLC38A6

176

Q8IZM9
PLALLPKIGFLGYTS

SLC38A6

181

Q8IZM9
LLVLATALFGQPPFK

IARS1

571

P41252
PTRFLFILLGPVGKG

SLC4A8

336

Q2Y0W8
FVLPLGSLFPQLKPS

ADRA1D

366

P25100
LLPKGTDVFPLLGSV

CYP2G1P

36

Q6ZSU1
TLLISTLTFPPGFGQ

CLCN2

371

P51788
TGFSVKILAPGIEPF

CLUH

46

O75153
LSLLPLKFFPIIVIG

TMPRSS3

41

P57727
LGLGFLVIPFLPASN

TMTC4

386

Q5T4D3
SLGFVIPQKLAGVLP

TICRR

791

Q7Z2Z1
GFLSQFPPGKVVITL

RHCE

96

P18577
PLPLGSKVVVLAGLF

SPINT2

191

O43291
VLFSASFTLGPGKLP

STAT6

386

P42226
IPTRFLFILLGPLGK

SLC4A10

366

Q6U841
AGPGKSLPVFAIILI

VSIG4

276

Q9Y279
PGKLLSPQTIFFQIL

nan

156

Q86TA4
LKVFFIGTFLGVAPP

TMEM41B

226

Q5BJD5
TTFLPFTLQELGGLP

THOP1

186

P52888