Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ATP-dependent activity	DNHD1 MYH3 MYH6 ABCA1 MCM8 ABCA13 ATAD5 PSMC1 MSH3 MSH4 ATP2C1 ATAD2B DNAH17 MYH15 ABCC12 SNRNP200 DDX28 DNAH11	5.29e-06	614	170	18	GO:0140657
Domain	AAA	ABCA1 MCM8 ABCA13 ATAD5 PSMC1 ATAD2B ABCC12 SNRNP200 DNAH11	4.66e-06	144	162	9	SM00382
Domain	AAA+_ATPase	ABCA1 MCM8 ABCA13 ATAD5 PSMC1 ATAD2B ABCC12 SNRNP200 DNAH11	4.66e-06	144	162	9	IPR003593
Domain	MacrogloblnA2_thiol-ester-bond	CPAMD8 C4A C4B	3.47e-05	8	162	3	IPR019565
Domain	Thiol-ester_cl	CPAMD8 C4A C4B	3.47e-05	8	162	3	PF10569
Domain	MacrogloblnA2_CS	CPAMD8 C4A C4B	3.47e-05	8	162	3	IPR019742
Domain	A2M	CPAMD8 C4A C4B	7.35e-05	10	162	3	PF00207
Domain	A2M_N_2	CPAMD8 C4A C4B	7.35e-05	10	162	3	IPR011625
Domain	A2M_comp	CPAMD8 C4A C4B	7.35e-05	10	162	3	IPR011626
Domain	A2M_recep	CPAMD8 C4A C4B	7.35e-05	10	162	3	PF07677
Domain	A2M_comp	CPAMD8 C4A C4B	7.35e-05	10	162	3	PF07678
Domain	A2M_N	CPAMD8 C4A C4B	7.35e-05	10	162	3	PF01835
Domain	A2M_N	CPAMD8 C4A C4B	7.35e-05	10	162	3	IPR002890
Domain	A-macroglobulin_rcpt-bd	CPAMD8 C4A C4B	7.35e-05	10	162	3	IPR009048
Domain	ALPHA_2_MACROGLOBULIN	CPAMD8 C4A C4B	7.35e-05	10	162	3	PS00477
Domain	A2M_N_2	CPAMD8 C4A C4B	7.35e-05	10	162	3	PF07703
Domain	Macroglobln_a2	CPAMD8 C4A C4B	7.35e-05	10	162	3	IPR001599
Domain	P-loop_NTPase	DNHD1 MYH3 MYH6 ABCA1 MCM8 ABCA13 ATAD5 SPEF2 PSMC1 CHST6 DAPK1 MSH3 MSH4 ATAD2B MYH15 ABCC12 SNRNP200 DDX28 DNAH11	1.44e-04	848	162	19	IPR027417
Domain	-	MSH3 MSH4	2.23e-04	3	162	2	3.30.420.110
Domain	Myosin_N	MYH3 MYH6 MYH15	2.70e-04	15	162	3	PF02736
Domain	Myosin_N	MYH3 MYH6 MYH15	2.70e-04	15	162	3	IPR004009
Domain	DNA_mmatch_repair_MutS_con_dom	MSH3 MSH4	4.44e-04	4	162	2	IPR007860
Domain	MutS_II	MSH3 MSH4	4.44e-04	4	162	2	PF05188
Domain	Myosin_tail_1	MYH3 MYH6 MYH15	4.75e-04	18	162	3	PF01576
Domain	Myosin_tail	MYH3 MYH6 MYH15	4.75e-04	18	162	3	IPR002928
Domain	Terpenoid_cyclase/PrenylTrfase	CPAMD8 C4A C4B	4.75e-04	18	162	3	IPR008930
Domain	Myosin-like_IQ_dom	MYH3 MYH6 MYH15	5.60e-04	19	162	3	IPR027401
Domain	-	MYH3 MYH6 MYH15	5.60e-04	19	162	3	4.10.270.10
Domain	Anaphylatoxin_comp_syst	C4A C4B	7.35e-04	5	162	2	IPR018081
Domain	MUTSd	MSH3 MSH4	7.35e-04	5	162	2	SM00533
Domain	MUTSac	MSH3 MSH4	7.35e-04	5	162	2	SM00534
Domain	MutS_V	MSH3 MSH4	7.35e-04	5	162	2	PF00488
Domain	Laminin_domII	LAMA3 LAMA5	7.35e-04	5	162	2	IPR010307
Domain	Anaphylatoxn_comp_syst_dom	C4A C4B	7.35e-04	5	162	2	IPR001840
Domain	DNA_mismatch_repair_MutS_clamp	MSH3 MSH4	7.35e-04	5	162	2	IPR007861
Domain	DNA_MISMATCH_REPAIR_2	MSH3 MSH4	7.35e-04	5	162	2	PS00486
Domain	MutS_IV	MSH3 MSH4	7.35e-04	5	162	2	PF05190
Domain	MutS_III	MSH3 MSH4	7.35e-04	5	162	2	PF05192
Domain	Laminin_aI	LAMA3 LAMA5	7.35e-04	5	162	2	IPR009254
Domain	DNA_mismatch_repair_MutS_C	MSH3 MSH4	7.35e-04	5	162	2	IPR000432
Domain	Laminin_I	LAMA3 LAMA5	7.35e-04	5	162	2	PF06008
Domain	Laminin_II	LAMA3 LAMA5	7.35e-04	5	162	2	PF06009
Domain	DNA_mismatch_repair_MutS_core	MSH3 MSH4	7.35e-04	5	162	2	IPR007696
Domain	VWA	COL6A2 ITGA11 ITGA1 VIT	1.41e-03	56	162	4	PF00092
Domain	ANATO	C4A C4B	1.53e-03	7	162	2	SM00104
Domain	ANAPHYLATOXIN_2	C4A C4B	1.53e-03	7	162	2	PS01178
Domain	ANAPHYLATOXIN_1	C4A C4B	1.53e-03	7	162	2	PS01177
Domain	ANATO	C4A C4B	1.53e-03	7	162	2	PF01821
Domain	Anaphylatoxin/fibulin	C4A C4B	1.53e-03	7	162	2	IPR000020
Domain	ERAP1-like_C_dom	ANPEP LNPEP	2.02e-03	8	162	2	IPR024571
Domain	HATC_C_dom	SPEF2 ZBED1	2.02e-03	8	162	2	IPR008906
Domain	Dimer_Tnp_hAT	SPEF2 ZBED1	2.02e-03	8	162	2	PF05699
Domain	ERAP1_C	ANPEP LNPEP	2.02e-03	8	162	2	PF11838
Domain	LAMININ_IVA	LAMA3 LAMA5	2.02e-03	8	162	2	PS51115
Domain	Laminin_B	LAMA3 LAMA5	2.02e-03	8	162	2	PF00052
Domain	LamB	LAMA3 LAMA5	2.02e-03	8	162	2	SM00281
Domain	A2M_N_2	CPAMD8 C4A	2.02e-03	8	162	2	SM01359
Domain	-	CPAMD8 C4A	2.02e-03	8	162	2	2.60.40.690
Domain	A2M_recep	CPAMD8 C4A	2.02e-03	8	162	2	SM01361
Domain	A2M	CPAMD8 C4A	2.02e-03	8	162	2	SM01360
Domain	Laminin_IV	LAMA3 LAMA5	2.02e-03	8	162	2	IPR000034
Domain	-	DNHD1 ABCA1 MCM8 ABCA13 ATAD5 SPEF2 PSMC1 CHST6 MSH3 MSH4 ATAD2B ABCC12 SNRNP200 DDX28 DNAH11	2.16e-03	746	162	15	3.40.50.300
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	RALGAPA1 MYH6 KRT78 PDE4D RPS4X SPTBN2 ETF1 DPYSL5 CKAP5 DYRK1A PSMC1 DAPK1 RPSA OGDH NHSL1 TENM4 SACS SVIL XRN1 PPP1R9B DLST C4A C4B UQCRC1 MARK2 SNRNP200 DNAH11 RPL18	4.46e-10	1431	171	28	37142655
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	RALGAPA1 UBR2 CPAMD8 PDE4D MCM8 ERV3-1 DPYSL5 LAMA3 DGKH GRIK1 CEP192 ADGRV1 HUWE1 OGDH PTK7 RANBP17 ATP2C1 GTF3C1 PKP3 TBC1D14 ZFHX2 AFF1 PPP1R9B UQCRC1 TMCC1 NSMAF FAM149A XPO7	1.08e-09	1489	171	28	28611215
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	KRT78 RPS4X SPTBN2 MKRN2 ETF1 CKAP5 PSMC1 LAMA3 RPSA MTPAP DNAJC2 NUP155 GTF3C1 TSR1 PKP3 GLS SVIL PPP1R9B DLST ZFR MARK2 NUDC SNRNP200 RPL18 FTSJ3	3.08e-09	1257	171	25	36526897
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	DNHD1 RPS4X RGS22 ETF1 CKAP5 PSMC1 DUOX2 RPSA MSH3 HUWE1 OGDH USP19 NUP155 GTF3C1 VPS33B TSR1 GLS RBPJ DLST ZFR UQCRC1 NUDC SNRNP200 RPL18 FTSJ3	3.63e-08	1425	171	25	30948266
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	RPS4X SPTBN2 CKAP5 RPSA HUWE1 NUP155 GTF3C1 TSR1 ATAD2B SYNE2 XRN1 ZFR UQCRC1 SNRNP200 XPO7 FTSJ3	1.68e-07	653	171	16	22586326
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	KRT78 RPS4X SPTBN2 CKAP5 PSMC1 RPSA HUWE1 NUP155 GTF3C1 SACS PKP3 SVIL SYNE2 ZFR MARK2 NUDC SNRNP200 RPL18 XPO7 FTSJ3	1.78e-07	1024	171	20	24711643
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	ATAD5 CKAP5 RPSA OGDH MTPAP RSBN1 NUP155 GTF3C1 TSR1 XRN1 DLST ZFR MARK2 SNRNP200 DDX28 RPL18 FTSJ3	2.40e-07	759	171	17	35915203
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	RALGAPA1 UBR2 ATAD5 SPTBN2 POLR2D PSMC1 CEP192 HUWE1 SORT1 NHSL1 NUP155 VPS33B TSR1 LNPEP SVIL SYNE2 PPP1R9B NUDC KNL1 FTSJ3	2.60e-07	1049	171	20	27880917
Pubmed	Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes.	RALGAPA1 UBR2 POLR2D OGDH PTK7 NHSL1 RSBN1 GTF3C1 DLST C4A UQCRC1 DDX28 KNL1 XPO7	4.49e-07	533	171	14	25544563
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	MYH3 MYH6 PCDHGC4 RPS4X SPEF2 SPTBN2 DUOX2 PABPC5 OGDH PTK7 GTF3C1 SACS FAM186A GLS SYNE2 XRN1 MYH15 CFAP74 PPP1R9B DLST ZFR CFAP46 RPL18	7.10e-07	1442	171	23	35575683
Pubmed	Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	SERINC2 NUP155 SACS ZBED1 SNRNP200 TMCC1 XPO7	7.16e-07	101	171	7	9872452
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	FRMPD4 RPS4X CKAP5 PSMC1 RPSA HUWE1 OGDH PTK7 NHSL1 ATP2C1 TENM4 UBE3A GLS XRN1 PPP1R9B DLST LNPK NUDC PCCB TMCC1	9.38e-07	1139	171	20	36417873
Pubmed	Targeting RICTOR Sensitizes SMAD4-Negative Colon Cancer to Irinotecan.	CYP24A1 USP19 DNAJC2 PTK7 UBE3A PKP3 MARK2 ARHGAP18	3.73e-06	183	171	8	31932471
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	MYH3 SPTBN2 CKAP5 PSMC1 DGKH HUWE1 MTPAP FRY GTF3C1 TRPM3 EXOC3L4 ATAD2B TBC1D14 SNRNP200 DSE	4.00e-06	736	171	15	29676528
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	PDE4D ANPEP SPC25 CKAP5 CEP192 DCAF16 MTPAP NUP155 GTF3C1 TSR1 SVIL MASTL ZFR GPC5 MARK2 NUDC SNRNP200 DDX28 KNL1	4.58e-06	1155	171	19	20360068
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	SCYL1 PSMC1 DGKH HUWE1 OGDH MTPAP USP19 NUP155 VPS33B GLS SYNE2 DLST ZFR UQCRC1 LNPK MARK2 NUDC TMCC1 DDX28 MGME1 RPL18 FTSJ3	4.69e-06	1496	171	22	32877691
Pubmed	Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells.	DPYSL5 CKAP5 PSMC1 RPSA HUWE1 OGDH DNAJC2 NUP155 UBE3A DLST ZFR UQCRC1 SNRNP200 FTSJ3	5.89e-06	665	171	14	30457570
Pubmed	Cross-Linking Mass Spectrometry Uncovers Interactions Between High-Density Lipoproteins and the SARS-CoV-2 Spike Glycoprotein.	MYH6 KRT78 SPTBN2 LAMA5 C4A C4B	6.50e-06	92	171	6	37343697
Pubmed	Nuclear Functions of Nucleolin through Global Proteomics and Interactomic Approaches.	RPS4X MTPAP GTF3C1 TSR1 SNRNP200 RPL18 FTSJ3	8.02e-06	145	171	7	27049334
Pubmed	Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation.	RPS4X DYRK1A RPSA PKP3 SVIL PPP1R9B DDX28 KNL1 RPL18 FTSJ3	1.32e-05	361	171	10	30344098
Pubmed	An N-terminal SIAH-interacting motif regulates the stability of the ubiquitin specific protease (USP)-19.	CKAP5 USP19 SNRNP200	1.37e-05	10	171	3	23500468
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	RALGAPA1 ATAD5 SPTBN2 CEP192 OGDH DNAJC2 PTK7 NUP155 SACS TSR1 LNPEP GLS SYNE2 DLST LNPK MARK2 NUDC SNRNP200 TMCC1 RPL18 FTSJ3	1.44e-05	1487	171	21	33957083
Pubmed	The nuclear interactome of DYRK1A reveals a functional role in DNA damage repair.	RALGAPA1 DYRK1A HUWE1 LNPEP AFF1 XPO7	1.47e-05	106	171	6	31024071
Pubmed	Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma.	PDE4D SPTBN2 CKAP5 LAMA3 RPSA MTPAP GTF3C1 PKP3 XRN1 DLST ZFR C4A MARK2 DDX28	1.72e-05	732	171	14	34732716
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	UBR2 SATB2 CKAP5 DYRK1A MSH3 HUWE1 MTPAP SORT1 GTF3C1 RBPJ ZFR UQCRC1 SNRNP200 MGME1 XPO7	2.40e-05	857	171	15	25609649
Pubmed	Copy number analysis of complement C4A, C4B and C4A silencing mutation by real-time quantitative polymerase chain reaction.	C4A C4B	2.40e-05	2	171	2	22737222
Pubmed	Deficiency of C4 from donor or recipient mouse fails to prevent renal allograft rejection.	C4A C4B	2.40e-05	2	171	2	16565498
Pubmed	Complete deficiencies of complement C4A and C4B including 2-bp insertion in codon 1213 are genetic risk factors of systemic lupus erythematosus in Thai populations.	C4A C4B	2.40e-05	2	171	2	15998580
Pubmed	High-throughput analysis of the C4 polymorphism by a combination of MLPA and isotype-specific ELISA's.	C4A C4B	2.40e-05	2	171	2	19062096
Pubmed	Activation of innate and humoral immunity in the peripheral nervous system of ALS transgenic mice.	C4A C4B	2.40e-05	2	171	2	19933335
Pubmed	Structural basis for the C4d.1/C4d.2 serologic allotypes of murine complement component C4.	C4A C4B	2.40e-05	2	171	2	2459207
Pubmed	Antigen-induced B cell apoptosis is independent of complement C4.	C4A C4B	2.40e-05	2	171	2	17645767
Pubmed	Anti-DNA autoreactivity in C4-deficient mice.	C4A C4B	2.40e-05	2	171	2	12207352
Pubmed	Complement C4A and C4B Gene Copy Number Study in Alzheimer's Disease Patients.	C4A C4B	2.40e-05	2	171	2	27758680
Pubmed	Genetically determined partial complement C4 deficiency states are not independent risk factors for SLE in UK and Spanish populations.	C4A C4B	2.40e-05	2	171	2	22387014
Pubmed	Complement C4 maintains peripheral B-cell tolerance in a myeloid cell dependent manner.	C4A C4B	2.40e-05	2	171	2	23749435
Pubmed	Copy number variations of complement component C4 are associated with Behçet's disease but not with ankylosing spondylitis associated with acute anterior uveitis.	C4A C4B	2.40e-05	2	171	2	23918728
Pubmed	Molecular genetics of androgen-dependent and -independent expression of mouse sex-limited protein.	C4A C4B	2.40e-05	2	171	2	3037333
Pubmed	Evidence of a role for C4 in modulating interstitial inflammation in experimental glomerulonephritis.	C4A C4B	2.40e-05	2	171	2	11726230
Pubmed	Quantitative variations in the expression of the mouse serum antigen Ss and its sex-limited allotype Slp.	C4A C4B	2.40e-05	2	171	2	4216347
Pubmed	Sequence determination of the thiolester site of the fourth component of human complement.	C4A C4B	2.40e-05	2	171	2	6950384
Pubmed	Visual demonstration of the organization of the human complement C4 and 21-hydroxylase genes by high-resolution fluorescence in situ hybridization.	C4A C4B	2.40e-05	2	171	2	8660986
Pubmed	Tissue-specific RNA processing for the complement C4 gene transcript in the H-2k mouse strain.	C4A C4B	2.40e-05	2	171	2	8428773
Pubmed	Complement C4 deficiency--a plausible risk factor for non-tuberculous mycobacteria (NTM) infection in apparently immunocompetent patients.	C4A C4B	2.40e-05	2	171	2	24638111
Pubmed	Transcriptional repression of C4 complement by hepatitis C virus proteins.	C4A C4B	2.40e-05	2	171	2	21345967
Pubmed	Restriction fragment analysis of H-2 recombinant mouse strains with crossovers between E alpha and C4 genes.	C4A C4B	2.40e-05	2	171	2	2572548
Pubmed	The complement component C4 of mammals.	C4A C4B	2.40e-05	2	171	2	2302180
Pubmed	Gene CNVs and protein levels of complement C4A and C4B as novel biomarkers for partial disease remissions in new-onset type 1 diabetes patients.	C4A C4B	2.40e-05	2	171	2	22151770
Pubmed	C4d-positive chronic rejection: a frequent entity with a poor outcome.	C4A C4B	2.40e-05	2	171	2	18091514
Pubmed	Comprehensive approach to study complement C4 in systemic lupus erythematosus: Gene polymorphisms, protein levels and functional activity.	C4A C4B	2.40e-05	2	171	2	29080553
Pubmed	Identification of a human LMX1 (LMX1.1)-related gene, LMX1.2: tissue-specific expression and linkage mapping on chromosome 9.	LMX1A LMX1B	2.40e-05	2	171	2	9441763
Pubmed	Genes for murine fourth complement component (C4) and sex-limited protein (Slp) identified by hybridization to C4- and Slp-specific cDNA.	C4A C4B	2.40e-05	2	171	2	6589636
Pubmed	C4 Deficiency is a predisposing factor for Streptococcus pneumoniae-induced autoantibody production.	C4A C4B	2.40e-05	2	171	2	25339671
Pubmed	A study of association of the complement C4 mutations with systemic lupus erythematosus in the Malaysian population.	C4A C4B	2.40e-05	2	171	2	17728371
Pubmed	Structure and organization of the C4 genes.	C4A C4B	2.40e-05	2	171	2	6149580
Pubmed	Sequence heterogeneity of murine complementary DNA clones related to the C4 and C4-Slp isoforms of the fourth complement component.	C4A C4B	2.40e-05	2	171	2	6149581
Pubmed	The follicular dendritic cell restricted epitope, FDC-M2, is complement C4; localization of immune complexes in mouse tissues.	C4A C4B	2.40e-05	2	171	2	12115608
Pubmed	Biochemistry and biology of anaphylatoxins.	C4A C4B	2.40e-05	2	171	2	3542363
Pubmed	C4 from C4-high and C4-low mouse strains have identical sequences in the region corresponding to the isotype-specific segment of human C4.	C4A C4B	2.40e-05	2	171	2	2387317
Pubmed	Do polymorphisms in transcription factors LMX1A and LMX1B influence the risk for Parkinson's disease?	LMX1A LMX1B	2.40e-05	2	171	2	19189040
Pubmed	Identification of the size and antigenic determinants of the human C4 gene by a polymerase chain-reaction-based amplification method.	C4A C4B	2.40e-05	2	171	2	16908004
Pubmed	Structural studies on the murine fourth component of complement (C4). IV. Demonstration that C4 and Slp are encoded by separate loci.	C4A C4B	2.40e-05	2	171	2	7365238
Pubmed	Interaction between the labile binding sites of the fourth (C4) and fifth (C5) human complement proteins and erythrocyte cell membranes.	C4A C4B	2.40e-05	2	171	2	7391573
Pubmed	Peritubular capillary C4d deposition in lupus nephritis different from antibody-mediated renal rejection.	C4A C4B	2.40e-05	2	171	2	17971360
Pubmed	Clinical features of patients with homozygous complement C4A or C4B deficiency.	C4A C4B	2.40e-05	2	171	2	29928053
Pubmed	Analysis of C4 and the C4 binding protein in the MRL/lpr mouse.	C4A C4B	2.40e-05	2	171	2	17971229
Pubmed	Genetic deficiency of C4 presenting with recurrent infections and a SLE-like disease. Genetic and immunologic studies.	C4A C4B	2.40e-05	2	171	2	6881182
Pubmed	Deficits in the mitochondrial enzyme α-ketoglutarate dehydrogenase lead to Alzheimer's disease-like calcium dysregulation.	OGDH DLST	2.40e-05	2	171	2	22169199
Pubmed	Partial C4 deficiency in juvenile idiopathic arthritis patients.	C4A C4B	2.40e-05	2	171	2	17921792
Pubmed	Complement activation and complement receptors on follicular dendritic cells are critical for the function of a targeted adjuvant.	C4A C4B	2.40e-05	2	171	2	21880985
Pubmed	Amino acid sequence around the thiol and reactive acyl groups of human complement component C4.	C4A C4B	2.40e-05	2	171	2	6978711
Pubmed	Plasma Complement 3 and Complement 4 Are Promising Biomarkers for Distinguishing NMOSD From MOGAD and Are Associated With the Blood-Brain-Barrier Disruption in NMOSD.	C4A C4B	2.40e-05	2	171	2	35898513
Pubmed	Borrelia burgdorferi outer surface protein C (OspC) binds complement component C4b and confers bloodstream survival.	C4A C4B	2.40e-05	2	171	2	28873507
Pubmed	Stimulation of p70S6 kinase via a growth hormone-controlled phosphatidylinositol 3-kinase pathway leads to the activation of a PDE4A cyclic AMP-specific phosphodiesterase in 3T3-F442A preadipocytes.	PDE4A PDE4D	2.40e-05	2	171	2	9520403
Pubmed	Studies on the murine Ss protein: demonstration that the Ss protein is functionally the fourth component of complement.	C4A C4B	2.40e-05	2	171	2	276882
Pubmed	Amino acid sequence of a polymorphic segment from fragment C4d of human complement component C4.	C4A C4B	2.40e-05	2	171	2	6832377
Pubmed	Recombination of two homologous MHC class III genes of the mouse (C4 and Slp) that accounts for the loss of testosterone dependence of sex-limited protein expression.	C4A C4B	2.40e-05	2	171	2	3794341
Pubmed	Fine-tuned characterization of RCCX copy number variants and their relationship with extended MHC haplotypes.	C4A C4B	2.40e-05	2	171	2	22785613
Pubmed	Association between complement 4 copy number variation and systemic lupus erythematosus: a meta-analysis.	C4A C4B	2.40e-05	2	171	2	32691186
Pubmed	The role of LNPEP and ANPEP gene polymorphisms in the pathogenesis of pre-eclampsia.	ANPEP LNPEP	2.40e-05	2	171	2	32619880
Pubmed	The androgen-dependent C4-Slp gene is driven by a constitutively competent promoter.	C4A C4B	2.40e-05	2	171	2	8390682
Pubmed	Structure and expression of murine fourth complement component (C4) and sex-limited protein (Slp).	C4A C4B	2.40e-05	2	171	2	3902619
Pubmed	Structural polymorphism of murine C4 and its linkage to H-2.	C4A C4B	2.40e-05	2	171	2	7373044
Pubmed	The chemical structure of the C4d fragment of the human complement component C4.	C4A C4B	2.40e-05	2	171	2	3696167
Pubmed	Restriction fragment length polymorphism of the murine C4 and Slp genes: two C4 groups.	C4A C4B	2.40e-05	2	171	2	1357031
Pubmed	Structural comparison of human C4A3 and C4B1 after proteolytic activation by C1s.	C4A C4B	2.40e-05	2	171	2	16098595
Pubmed	The ZnR/GPR39 interacts with the CaSR to enhance signaling in prostate and salivary epithelia.	GPR39 CASR	2.40e-05	2	171	2	24264723
Pubmed	Increased frequency of C4B*Q0 alleles in patients with Henoch-Schönlein purpura.	C4A C4B	2.40e-05	2	171	2	15787745
Pubmed	Neuropil contraction in relation to Complement C4 gene copy numbers in independent cohorts of adolescent-onset and young adult-onset schizophrenia patients-a pilot study.	C4A C4B	2.40e-05	2	171	2	30026462
Pubmed	A molecular map of the human major histocompatibility complex class III region linking complement genes C4, C2 and factor B.	C4A C4B	2.40e-05	2	171	2	6559257
Pubmed	Complement C4 Is Reduced in iPSC-Derived Astrocytes of Autism Spectrum Disorder Subjects.	C4A C4B	2.40e-05	2	171	2	34299197
Pubmed	Assessment of complement C4 gene copy number using the paralog ratio test.	C4A C4B	2.40e-05	2	171	2	20506482
Pubmed	Polymerase chain reaction based C4AQ0 and C4BQ0 genotyping: association with systemic lupus erythematosus in southwest Han Chinese.	C4A C4B	2.40e-05	2	171	2	12480675
Pubmed	Identification of a novel putative Ran-binding protein and its close homologue.	RANBP17 XPO7	2.40e-05	2	171	2	11071879
Pubmed	Low C4, C4A and C4B gene copy numbers are stronger risk factors for juvenile-onset than for adult-onset systemic lupus erythematosus.	C4A C4B	2.40e-05	2	171	2	26800705
Pubmed	Murine complement C4 is not required for experimental autoimmune encephalomyelitis.	C4A C4B	2.40e-05	2	171	2	15390104
Pubmed	In situ-RT-PCR and immunohistochemistry for the localisation of the mRNA of the alpha 3 chain of laminin and laminin-5 during human organogenesis.	LAMA3 LAMA5	2.40e-05	2	171	2	12382139
Pubmed	Importance of the alpha 3-fragment of complement C4 for the binding with C4b-binding protein.	C4A C4B	2.40e-05	2	171	2	1699796
Pubmed	Molecular cloning and characterization of complementary and genomic DNA clones for mouse C4 and Slp.	C4A C4B	2.40e-05	2	171	2	2997024
Pubmed	Constitutive expression of Slp genes in mouse strain B10.WR directed by C4 regulatory sequences.	C4A C4B	2.40e-05	2	171	2	3624865
GeneFamily	C3 and PZP like, alpha-2-macroglobulin domain containing	CPAMD8 C4A C4B	1.94e-05	9	113	3	1234
GeneFamily	Myosin heavy chains	MYH3 MYH6 MYH15	1.02e-04	15	113	3	1098
GeneFamily	Aminopeptidases\|CD molecules	ANPEP XPNPEP2 LNPEP	1.52e-04	17	113	3	104
GeneFamily	MutS homologs\|PWWP domain containing	MSH3 MSH4	3.82e-04	5	113	2	1026
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	CEP192 TMEM132C SACS PCDH11X PPP1R9B KNL1	9.66e-04	181	113	6	694
GeneFamily	LIM class homeoboxes	LMX1A LMX1B	2.45e-03	12	113	2	522
GeneFamily	Laminin subunits	LAMA3 LAMA5	2.45e-03	12	113	2	626
GeneFamily	ATP binding cassette subfamily A	ABCA1 ABCA13	3.35e-03	14	113	2	805
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	RALGAPA1 DYRK1A DGKH ITGA1 HUWE1 STAT4 ATP2C1 LNPEP GLS SYNE2	3.04e-09	188	170	10	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|World / Lineage, Cell type, age group and donor	CPAMD8 PDE4D DSCAM GPR39 LAMA3 LAMA5 DAPK1 ADGRV1 RANBP17 GPC5	3.54e-09	191	170	10	d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CPAMD8 SATB2 ABCA13 LAMA3 DAPK1 CASR DGKH SYT16 SVIL SYNE2	4.11e-09	194	170	10	e577d9e88390b36b5a09b97fe1026089892275a3
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DSCAM GPR39 LAMA3 LAMA5 DAPK1 ADGRV1 RANBP17 EVA1A GPC5	3.10e-08	179	170	9	cb38b54261a7af5ee3347e64c8aa880a77ed0763
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRMPD4 ABCA13 RGS22 ADGRV1 TENM4 TRPM3 PCDH11X MYH15 DNAH11	3.94e-08	184	170	9	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRMPD4 ABCA13 RGS22 ADGRV1 TENM4 TRPM3 PCDH11X MYH15 DNAH11	3.94e-08	184	170	9	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRMPD4 ABCA13 RGS22 ADGRV1 TENM4 TRPM3 PCDH11X MYH15 DNAH11	3.94e-08	184	170	9	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CPAMD8 PDE4D GPR39 SPTBN2 C4orf54 TRPM3 GLS PCDH11X AFF1	4.12e-08	185	170	9	d602a9b35e86e6f2a14a58e40fc4fb97f5fa3b08
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CPAMD8 GPR39 LAMA3 DAPK1 ADGRV1 RANBP17 NHSL1 FRY GPC5	5.19e-08	190	170	9	8aea807a2bcf0b653b4de6202b6ecb0f0683cc2e
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CPAMD8 PDE4D SPTBN2 C4orf54 TRPM3 PKP3 GLS AFF1 PAPPA	5.67e-08	192	170	9	d5ec4cdb15620a5abfc83577353501186c2bc86a
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CPAMD8 PDE4D SPTBN2 C4orf54 TRPM3 PKP3 GLS AFF1 PAPPA	5.93e-08	193	170	9	5da60321bcf761913eb30779b6d8b1e933c5e51e
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CPAMD8 PDE4D SPTBN2 C4orf54 FRY TRPM3 GLS PAPPA	5.37e-07	183	170	8	b5ede5a0048c585b73c00e88aeddbcaf669347b1
ToppCell	RA-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	PDE4D LAMA3 DGKH ITGA1 SORT1 FRY GLS MYH15	5.37e-07	183	170	8	cae2ee08f985a6f005b4b8e959e465350315156a
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CPAMD8 GPR39 LAMA3 LAMA5 ADGRV1 RANBP17 EVA1A GPC5	6.32e-07	187	170	8	4ae7465174e0295d2c3b614b321a3b2f514dd22a
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CPAMD8 PDE4D SPTBN2 FRY TRPM3 GLS AFF1 PAPPA	6.32e-07	187	170	8	e3095455d2f255854f339f6b05fa87852af0700f
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CPAMD8 PDE4D SPTBN2 FRY TRPM3 GLS AFF1 PAPPA	6.85e-07	189	170	8	3a295c215b5c18e7c673f92b7af5be523421682c
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CPAMD8 PDE4D SPTBN2 FRY TRPM3 GLS AFF1 PAPPA	6.85e-07	189	170	8	fc88c51ace7d883c01617f3f9b5fab70cc91cc09
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CPAMD8 LAMA3 DAPK1 CASR DGKH SYT16 SVIL SYNE2	8.02e-07	193	170	8	f42a0f02ed00fe1bb833ff0a0640d9131bca89bd
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CPAMD8 LAMA3 DAPK1 CASR DGKH SYT16 SVIL SYNE2	8.02e-07	193	170	8	42df7ed37d11fb542b4d1d714b6f87ae8e1396a6
ToppCell	droplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	B3GALT1 COL6A2 GPR39 PKDREJ PTK7 TMEM132C PCDH11X C4B	8.34e-07	194	170	8	7826fe5eb254ac032de0d978f39585a40e0b3ee4
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CPAMD8 PDE4D SPTBN2 C4orf54 FRY TRPM3 GLS PAPPA	8.34e-07	194	170	8	4d6c9b016e3a0641954a8ea10c97d1cd76fadd9f
ToppCell	BAL-Severe-Lymphocyte-T/NK-NK_cell\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	PDE4D RPS4X RPSA ITGA1 STAT4 LNPEP SYNE2 RPL18	9.01e-07	196	170	8	64b23d819efddb25024c86f2e1b5dc4159337ddd
ToppCell	BAL-Severe-Lymphocyte-T/NK-NK_cell-NK\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	PDE4D RPS4X RPSA ITGA1 STAT4 LNPEP SYNE2 RPL18	9.01e-07	196	170	8	ba46f80d1497eaf4d71b59504106ba4b84e4ff9f
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	IL24 PDE4D RPS4X RPSA ITGA1 STAT4 ARHGEF3 PARP15	9.01e-07	196	170	8	c9fb81a0578db6d278b8582d7b3add6c407e6dcf
ToppCell	BAL-Severe-Lymphocyte-T/NK-NK_cell-NK-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	PDE4D RPS4X RPSA ITGA1 STAT4 LNPEP SYNE2 RPL18	9.01e-07	196	170	8	eb0b711ca6da7b5e5313791c3c3985358e2a222e
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	PDE4D GPR39 DYRK1A ADGRV1 RANBP17 NHSL1 GPC5 TMCC1	9.72e-07	198	170	8	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	RALGAPA1 UBR2 STAT4 ATAD2B GLS SYNE2 SNRNP200 PARP15	1.01e-06	199	170	8	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	LAMA3 DAPK1 ADGRV1 TRPM3 EVA1A PKP3 SYNE2 APOL6	1.05e-06	200	170	8	8683445ad5b70748c4a1f12eb77d47623085147e
ToppCell	COVID-19_Mild-Neu_0\|World / 5 Neutrophil clusters in COVID-19 patients	IL24 B3GALT1 TRPC3 DPYSL5 ST6GALNAC6 TENM4 FAM186A	1.14e-06	140	170	7	93f024473b1bb3bf93ae776fd6a8fc5e93d013f0
ToppCell	droplet-Marrow-BM-30m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCTN3 PNLIP DSCAM ADGRV1 SLC30A7 EXOC3L4 DSE	3.28e-06	164	170	7	b77995958c938e10a526118f75d78cee72e0b207
ToppCell	5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EECs\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SATB2 DGKH MSH4 ADGRV1 ST8SIA3 TRPM3 LMX1A	3.42e-06	165	170	7	4b4e75ad0eb0a6b00c30a000ec6267e23ba2e496
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DSCAM ABCA13 ADGRV1 MYH15 C4B DNAH11 RPL18	4.00e-06	169	170	7	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CPAMD8 PDE4D GPR39 LAMA5 DAPK1 ADGRV1 SYNE2	4.16e-06	170	170	7	a2c738e441ced90eeeb1fcc6ca3269b918aaa298
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DSCAM GPR39 LAMA3 RANBP17 NHSL1 EVA1A GPC5	4.67e-06	173	170	7	b799c06a6a5754668e789f70c0c8bc1508568575
ToppCell	367C-Epithelial_cells-Epithelial-I_(AT1)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	GPR39 LAMA3 LAMA5 ADGRV1 RANBP17 SYT16 EVA1A	4.85e-06	174	170	7	edf839d79ac58921f4e788f3b2cb2ae0d6af4b9e
ToppCell	367C-Epithelial_cells-Epithelial-I_(AT1)\|367C / Donor, Lineage, Cell class and subclass (all cells)	GPR39 LAMA3 LAMA5 ADGRV1 RANBP17 SYT16 EVA1A	4.85e-06	174	170	7	65539f69100db0b7d90b1b39ee15ab8281f86461
ToppCell	10x3'2.3-week_12-13-Mesenchymal_myocytic-stroma-muscle_stem_cell\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	SATB2 FRMPD4 AKAP3 DUOX2 PABPC5 TENM4 PAPPA	5.63e-06	178	170	7	8f31b3fac51591f7f2bcb898c07708b3e9f93a16
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SATB2 PDE4D ABCA13 TRPM3 EVA1A EXOC3L4 SLC28A1	5.84e-06	179	170	7	58ae5a97fe2a14e1c6fdeb886397eb06fdaf0428
ToppCell	COVID-19-kidney-PCT-S2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PDE4D ANPEP CYP24A1 TRPM3 SYNE2 SLC28A1 PAPPA	6.06e-06	180	170	7	358923e4228035a3e90e2957392089219e90dcd7
ToppCell	Control-Epithelial_cells-Airway_club\|Control / group, cell type (main and fine annotations)	CPAMD8 PDE4D DAPK1 ADGRV1 SVIL GPC5 FAM149A	6.28e-06	181	170	7	c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCell	RA-13._Vascular_Smooth_Muscle\|RA / Chamber and Cluster_Paper	LAMA3 DGKH ITGA1 SORT1 FRY GLS MYH15	6.75e-06	183	170	7	818fd886e0188091310825f9145fa53328f2c979
ToppCell	COVID-19-kidney-PCT-S1\|kidney / Disease (COVID-19 only), tissue and cell type	SATB2 ANPEP ABCA13 CYP24A1 TRPM3 SYNE2 SLC28A1	7.00e-06	184	170	7	51ed1ebfdef45149541917c66cbacad87072e51f
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CPAMD8 PDE4D GPR39 DAPK1 ADGRV1 GPC5 FAM149A	7.25e-06	185	170	7	98b8ee42b89d97e4c9db01740e0c193503c68f2c
ToppCell	COVID-19-kidney-Mito-rich_PCT\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PDE4D ANPEP CYP24A1 TRPM3 SYNE2 SLC28A1 PAPPA	7.25e-06	185	170	7	1bbc2ba8a20f72f61981b1301cdd6018cdd9150d
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-mesothelial_cell-Mesothelium_(RGS5+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	B3GALT1 RGS22 LAMA5 DAPK1 FRY SCN7A ARHGEF3	7.25e-06	185	170	7	11fbea1eb1d9a3e4480d0d2b0f7b02e2866b8142
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CPAMD8 PDE4D GPR39 DAPK1 ADGRV1 GPC5 FAM149A	7.51e-06	186	170	7	2ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	RGS22 LAMA3 ADGRV1 TENM4 FAM186A MYH15 PPP1R9B	7.51e-06	186	170	7	23b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell	Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|World / Lineage, Cell type, age group and donor	CPAMD8 PDE4D GPR39 DAPK1 ADGRV1 GPC5 FAM149A	7.78e-06	187	170	7	81cc8435b2704a9a8287b3f54acaae0f11dd4ac7
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VPS33B TRPM3 C4A C4B GPC5 NSMAF	7.85e-06	123	170	6	a45d6907c041ad3f3218cd46dccfc25d4bd961cb
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	GPR39 LAMA3 LAMA5 RANBP17 EVA1A GLS GPC5	8.05e-06	188	170	7	eea652bab161f19148a883e7e3fe2523b36b3cea
ToppCell	LA-13._Vascular_Smooth_Muscle\|LA / Chamber and Cluster_Paper	PDE4D LAMA3 ITGA1 SORT1 FRY GLS SVIL	8.05e-06	188	170	7	34e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCell	COVID-19-Epithelial_cells\|COVID-19 / group, cell type (main and fine annotations)	PDE4D GPR39 LAMA3 ADGRV1 RANBP17 GPC5 DNAH11	8.05e-06	188	170	7	c9cdee6f8d42ee69f5fb335f25084603c511bd29
ToppCell	Control-Epithelial-Ciliated\|Control / Disease state, Lineage and Cell class	ABCA13 SPEF2 RGS22 CHST6 CFAP74 CFAP46 DNAH11	8.33e-06	189	170	7	c007fccd08728db3ea99af9da91d67b9b16dabb3
ToppCell	pdx-Tumor_cells-T1\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	MCM8 ATAD5 SPC25 CKAP5 CEP192 KNL1 MGME1	8.63e-06	190	170	7	d06ee5f89f1cec8db6897fe3b2a890a07cd3697b
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PDE4D SPTBN2 C4orf54 TRPM3 GLS AFF1 PAPPA	8.63e-06	190	170	7	078f4be52fa4cc8dd9c8d7a2b6d9631c3d902285
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PDE4D RPS4X SPTBN2 C4orf54 TRPM3 PKP3 PAPPA	8.93e-06	191	170	7	0a0719a0a49ae0099d61e22585ac74c10c24b4a2
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	GPR39 LAMA3 DAPK1 ADGRV1 RANBP17 NHSL1 GPC5	8.93e-06	191	170	7	ca5669bd6f4a17471acae3eb229f845cc2e08efa
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CASR DGKH SYT16 TENM4 LNPEP SVIL ARHGEF3	8.93e-06	191	170	7	9032aa974aa1b7b1095b8d1b58dcb087358a5001
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CASR DGKH SYT16 TENM4 LNPEP SVIL ARHGEF3	8.93e-06	191	170	7	5717809a1476c20f65bce722c5a57cff92ee0d7a
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-mesothelial_cell\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	B3GALT1 RGS22 GDF6 LAMA5 DAPK1 FRY SCN7A	9.23e-06	192	170	7	2f539653a20006bef814e6b4acd1023d6fdad5c6
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CPAMD8 PDE4D SPTBN2 C4orf54 TRPM3 AFF1 PAPPA	9.23e-06	192	170	7	9e031bf93eb8757fdd0cc22f01b44e48f85532d5
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CPAMD8 PDE4D SPTBN2 C4orf54 TRPM3 AFF1 PAPPA	9.23e-06	192	170	7	3d777d07878269b87ec7e1f06489cae7c989d633
ToppCell	3'_v3-Lung-Lymphocytic_T_CD4\|Lung / Manually curated celltypes from each tissue	RPS4X RPSA ITGA1 STAT4 RSBN1 SYNE2 RPL18	9.23e-06	192	170	7	fd19cd0b5330448bef8debd753285adbc8b958a2
ToppCell	human_hepatoblastoma-Tumor_cells-T1\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	MCM8 ATAD5 SPC25 CKAP5 CEP192 KNL1 MGME1	9.55e-06	193	170	7	4b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCell	Fetal_29-31_weeks-Epithelial\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CPAMD8 GPR39 LAMA3 DAPK1 ADGRV1 RANBP17 GPC5	9.55e-06	193	170	7	a0ca3231992f14abcf1a6129573bace320e89d2a
ToppCell	Control-Fibroblasts-Intermediate_pathological_FB\|Control / group, cell type (main and fine annotations)	COL6A2 ITGA11 ITGA1 TMEM132C TENM4 SCN7A PAPPA	9.88e-06	194	170	7	03a269f75a481ea54aea8e6444605db8d6df493d
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CPAMD8 GPR39 SPTBN2 DAPK1 SORT1 AFF1 PAPPA	9.88e-06	194	170	7	04bfc555743f7d8821439d05ae442d15e9886c59
ToppCell	COVID-19-Heart-Fib_2\|Heart / Disease (COVID-19 only), tissue and cell type	COL6A2 ITGA11 VIT TENM4 LMX1A SCN7A PAPPA	9.88e-06	194	170	7	d91c9f2ec47319051fc398320693fddbe8bbd4d6
ToppCell	Control-Epithelial-Ciliated\|World / Disease state, Lineage and Cell class	ABCA13 SPEF2 RGS22 CHST6 CFAP74 CFAP46 DNAH11	9.88e-06	194	170	7	958e648138676d46698090b4046cb484083ae449
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CPAMD8 GPR39 SPTBN2 DAPK1 SORT1 AFF1 PAPPA	9.88e-06	194	170	7	69bff17df4a760ccf081cf52ff04af02c14f448d
ToppCell	Entopeduncular-Macroglia-ASTROCYTE\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	ITGA11 ERV3-1 CHI3L1 VIT EVA1A EXOC3L4	1.03e-05	129	170	6	c37bdd6c0b2944fbfa064922954ea0e263160e2a
ToppCell	Entopeduncular-Macroglia-ASTROCYTE-Gja1\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	ITGA11 ERV3-1 CHI3L1 VIT EVA1A EXOC3L4	1.03e-05	129	170	6	8648ae59f7aca0f5b4983bdb4a65b03b2ca761e1
ToppCell	critical-Lymphoid-CTL\|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	ITGA1 STAT4 LNPEP SYNE2 RBPJ APOL6 ARHGEF3	1.06e-05	196	170	7	c861f017aa9050282aa81c5a445bae399df00e4f
ToppCell	wk_20-22-Epithelial-Distal_epithelial\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	LAMA3 LAMA5 RANBP17 NHSL1 EVA1A PKP3 GPC5	1.06e-05	196	170	7	cd507ee2baf4f52d6498811b3510d3164b56311f
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL6A2 ABCA1 PDE4D PTK7 EVA1A PAPPA PTGDR2	1.06e-05	196	170	7	2ab9735aa7a7e95dcf6b0bdf0427f7b57f6349ee
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	MROH5 LAMA3 DAPK1 ADGRV1 SYNE2 APOL6 PCDH11X	1.09e-05	197	170	7	b94645d57efe8d9e032bffb8c89af1f425c6421e
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	DGKH STAT4 LNPEP SYNE2 XRN1 SNRNP200 PARP15	1.09e-05	197	170	7	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	Severe-Lymphoid-NK-NK\|Severe / Condition, Lineage, Cell class and cell subclass	PDE4D RPS4X RPSA ITGA1 STAT4 LNPEP SYNE2	1.09e-05	197	170	7	d5b94f9f73e9d050245841b19b046242a32c6258
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SPEF2 RGS22 SYNE2 ZFHX2 CFAP74 CFAP46 DNAH11	1.09e-05	197	170	7	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL6A2 ITGA1 TMEM132C TENM4 SCN7A PAPPA ABCC12	1.09e-05	197	170	7	44673c38384453207871d3fd8e8ba9093cc06bc5
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-T_lymphocytic\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	PDE4D RPS4X RPSA ITGA1 STAT4 SYNE2 RPL18	1.13e-05	198	170	7	1fa0ea06453d6b979039f63454e7f9c69323a350
ToppCell	Severe-Lymphoid-NK\|Severe / Condition, Lineage, Cell class and cell subclass	PDE4D RPS4X RPSA ITGA1 STAT4 LNPEP SYNE2	1.13e-05	198	170	7	26b6d20527d22ce68067cdaea6b4330cb779f91b
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FRMPD4 SYT16 FRY TENM4 UBE3A GLS PCDH11X	1.13e-05	198	170	7	8ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCell	Bronchial-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	GPR39 LAMA3 DAPK1 ADGRV1 RANBP17 NHSL1 GPC5	1.17e-05	199	170	7	5f7da3eab58ace6cddb3179a415cd839d5767958
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	GPR39 LAMA3 DAPK1 ADGRV1 RANBP17 NHSL1 GPC5	1.17e-05	199	170	7	725610310e5c5fd7120c0be9acb55bf152026ddd
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	GPR39 LAMA3 DAPK1 ADGRV1 RANBP17 NHSL1 GPC5	1.17e-05	199	170	7	8587bd98de7767a575088afbea07a1feb4516b9b
ToppCell	Bronchial-10x5prime-Stromal-Fibroblastic-Fibro_immune_recruiting\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	COL6A2 LAMA3 TMEM132C EXOC3L4 SCN7A PCDH11X C4B	1.17e-05	199	170	7	0cdbedf09ec72734b86ddab3fec562e066afed92
ToppCell	Parenchymal-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	GPR39 LAMA3 DAPK1 ADGRV1 RANBP17 NHSL1 GPC5	1.17e-05	199	170	7	5cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCell	lymphoid-NK_cell-NK_cell\|NK_cell / Lineage, cell class and subclass	RIN3 PDE4D ETF1 STAT4 SYNE2 APOL6 XRN1	1.17e-05	199	170	7	945fbf5845403a8b22d04963f50ad69c414b6153
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_1\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	LAMA3 DAPK1 TRPM3 PKP3 SYNE2 APOL6 PCDH11X	1.17e-05	199	170	7	a270630626df614f8605abddb7dee7c4d74f6149
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	PDE4D RPS4X RPSA STAT4 RSBN1 SYNE2 RPL18	1.17e-05	199	170	7	3003badee037d4d63a8018a74c0aea213d049e43
ToppCell	MS-Multiple_Sclerosis-Lymphocyte-T/NK-CD4+_Tem\|Multiple_Sclerosis / Disease, condition lineage and cell class	PDE4D RPS4X RPSA ITGA1 STAT4 SYNE2 RPL18	1.17e-05	199	170	7	79145d931a250c69a643936fea147e2bd50b4d6d
ToppCell	mild-gd_T\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	COL6A2 PDE4D STAT4 SYNE2 APOL6 XRN1 PARP15	1.20e-05	200	170	7	109f673a4967ffa52270a0b4f818b3461288db44
ToppCell	Non-neuronal-Dividing-IPC-IPC-div2\|World / Primary Cells by Cluster	MCM8 ATAD5 SPC25 ADGRV1 SYNE2 MASTL KNL1	1.20e-05	200	170	7	4923d7a4f00853c4d76fc1cc0fa82d522a2302e7
ToppCell	Non-neuronal-Dividing-IPC-IPC-div2-5\|World / Primary Cells by Cluster	MCM8 ATAD5 SPC25 ADGRV1 SYNE2 MASTL KNL1	1.20e-05	200	170	7	dc1c1506823eaa105f1532c6b5d4efa14e788314
ToppCell	Substantia_nigra-Macroglia-ASTROCYTE\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	ERV3-1 CHI3L1 EVA1A EXOC3L4 MYH15 ABCC12	1.28e-05	134	170	6	a632d78890fcc20db81d2cf6b299470706d2e182
ToppCell	Substantia_nigra-Macroglia-ASTROCYTE-Gja1\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	ERV3-1 CHI3L1 EVA1A EXOC3L4 MYH15 ABCC12	1.28e-05	134	170	6	8be2db71d9d29f9a57a64efdc89cf8c3e32b363b
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PNLIP SYT16 SCN7A C4A GPC5 ARHGEF3	1.78e-05	142	170	6	5b6b0c611c83b23ef7289854a515b78f6cf84500
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PDE4D SPTBN2 TRPM3 PKP3 GLS PAPPA	2.01e-05	145	170	6	bfa196ac1db7acbfcbb2ba9f137036a95e16e091
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CPAMD8 PDE4D SPTBN2 TRPM3 PKP3 PAPPA	2.17e-05	147	170	6	64fa0753a3a79f492ef8acc6942bf90d379a983f
Disease	mean platelet volume	RIN3 PCDHGC4 ATAD5 TRPC3 CYP24A1 SPC25 DYRK1A CASR NARF TRMU RSBN1 FRY TRPM3 EXOC3L4 ATAD2B GLS SVIL SYNE2 TBC1D14 AFF1 ARHGEF3 ARHGAP18 DSE	2.50e-08	1020	170	23	EFO_0004584
Disease	triglycerides in LDL measurement	ABCA1 SYNE2 AFF1 NUDC PCCB	1.80e-05	56	170	5	EFO_0022320
Disease	autosomal dominant hyaline body myopathy (implicated_via_orthology)	MYH3 MYH6 MYH15	2.19e-05	10	170	3	DOID:0111269 (implicated_via_orthology)
Disease	distal arthrogryposis type 2B3 (implicated_via_orthology)	MYH3 MYH6 MYH15	2.19e-05	10	170	3	DOID:0111602 (implicated_via_orthology)
Disease	distal arthrogryposis type 1 (implicated_via_orthology)	MYH3 MYH6 MYH15	2.19e-05	10	170	3	DOID:0111596 (implicated_via_orthology)
Disease	dilated cardiomyopathy 1S (implicated_via_orthology)	MYH3 MYH6 MYH15	2.19e-05	10	170	3	DOID:0110454 (implicated_via_orthology)
Disease	congenital myopathy 6 (implicated_via_orthology)	MYH3 MYH6 MYH15	2.19e-05	10	170	3	DOID:0080719 (implicated_via_orthology)
Disease	inclusion body myositis (implicated_via_orthology)	MYH3 MYH6 MYH15	2.19e-05	10	170	3	DOID:3429 (implicated_via_orthology)
Disease	distal arthrogryposis type 2A (implicated_via_orthology)	MYH3 MYH6 MYH15	2.19e-05	10	170	3	DOID:0111605 (implicated_via_orthology)
Disease	familial hypertrophic cardiomyopathy (implicated_via_orthology)	MYH3 MYH6 MYH15	2.19e-05	10	170	3	DOID:0080326 (implicated_via_orthology)
Disease	distal myopathy (implicated_via_orthology)	MYH3 MYH6 MYH15	3.98e-05	12	170	3	DOID:11720 (implicated_via_orthology)
Disease	myotonia congenita (implicated_via_orthology)	MYH3 MYH6 MYH15	3.98e-05	12	170	3	DOID:2106 (implicated_via_orthology)
Disease	restrictive cardiomyopathy (implicated_via_orthology)	MYH3 MYH6 MYH15	5.15e-05	13	170	3	DOID:397 (implicated_via_orthology)
Disease	immature platelet measurement	TRPM3 EXOC3L4 SVIL TBC1D14 PPP1R9B ARHGEF3	6.78e-05	119	170	6	EFO_0803541
Disease	distal arthrogryposis (implicated_via_orthology)	MYH3 MYH6 MYH15	8.12e-05	15	170	3	DOID:0050646 (implicated_via_orthology)
Disease	hypercalcemia (is_implicated_in)	CYP24A1 CASR	9.86e-05	3	170	2	DOID:12678 (is_implicated_in)
Disease	triglycerides in large LDL measurement	ABCA1 SYNE2 AFF1 PCCB	1.10e-04	43	170	4	EFO_0022319
Disease	lymphocyte count	TCTN3 SH3TC2 PDE4A PDE4D PCDHGC4 SPEF2 SPC25 ITGA1 FAM43B RSBN1 TENM4 EVA1A PKP3 ATAD2B DNAH17 TBC1D14 AFF1 PAPPA ARHGEF3 NSMAF KNL1	1.11e-04	1464	170	21	EFO_0004587
Disease	sphingomyelin 14:0 measurement	PDE4D TRPM3 SYNE2	1.20e-04	17	170	3	EFO_0010390
Disease	cortical thickness	CPAMD8 SATB2 RIN3 SPTBN2 GDF6 DPYSL5 AS3MT RPSA MSH3 ADGRV1 VIT NHSL1 LMX1A GLS AFF1 ARHGAP18 PCCB	2.53e-04	1113	170	17	EFO_0004840
Disease	protein-glutamine gamma-glutamyltransferase e measurement	SPC25 ITGA1 EXOC3L4 NUDC	4.03e-04	60	170	4	EFO_0020690
Disease	triglyceride measurement, intermediate density lipoprotein measurement	ABCA1 SYNE2 AFF1 NUDC PCCB	4.69e-04	111	170	5	EFO_0004530, EFO_0008595
Disease	lung carcinoma	UBR2 PDE4D ATAD5 OGDH TMEM132C FRY TENM4 GPC5 DNAH11 XPO7	5.12e-04	482	170	10	EFO_0001071
Disease	IGF-1 measurement	ITGA11 PDE4A PDE4D SPTBN2 DPYSL5 DGKH OGDH SYNE2 NUDC NSMAF	5.63e-04	488	170	10	EFO_0004627
Disease	posterior urethral valve	UBR2 RIN3 PTK7	6.15e-04	29	170	3	MONDO_0019640
Disease	Schizophrenia	ABCA1 PDE4A PDE4D ABCA13 SPTBN2 GRIK1 CHI3L1 TENM4 LMX1A LMX1B PPP1R9B MARK2 ARHGAP18 WNK3	6.26e-04	883	170	14	C0036341
Disease	multiple sclerosis	NLRP11 CPAMD8 PDE4A SPEF2 CYP24A1 STAT4 SLC30A7 SVIL AFF1 GPC5 ARHGEF3	6.96e-04	594	170	11	MONDO_0005301
Disease	cardiomyopathy (implicated_via_orthology)	MYH3 MYH6 CASR MYH15	7.65e-04	71	170	4	DOID:0050700 (implicated_via_orthology)
Disease	nephrolithiasis	CYP24A1 CASR DGKH	9.03e-04	33	170	3	EFO_0004253
Disease	Spinocerebellar Ataxia Type 2	TRPC3 SPTBN2 SCYL1	9.86e-04	34	170	3	C0752121
Disease	Spinocerebellar Ataxia Type 1	TRPC3 SPTBN2 SCYL1	9.86e-04	34	170	3	C0752120
Disease	Spinocerebellar Ataxia Type 5	TRPC3 SPTBN2 SCYL1	9.86e-04	34	170	3	C0752123
Disease	Spinocerebellar Ataxia Type 7	TRPC3 SPTBN2 SCYL1	9.86e-04	34	170	3	C0752125
Disease	Spinocerebellar Ataxia Type 6 (disorder)	TRPC3 SPTBN2 SCYL1	9.86e-04	34	170	3	C0752124
Disease	Ataxia, Spinocerebellar	TRPC3 SPTBN2 SCYL1	9.86e-04	34	170	3	C0087012
Disease	Global developmental delay	FRMPD4 SZT2 SPTBN2 TRPM3 LNPK	1.06e-03	133	170	5	C0557874
Disease	Spinocerebellar Ataxia Type 4	TRPC3 SPTBN2 SCYL1	1.07e-03	35	170	3	C0752122
Disease	testosterone measurement	B3GALT1 SATB2 PDE4A DSCAM CYP24A1 GDF6 ETF1 AS3MT DCAF16 PKDREJ FAM186A SYNE2 SLC28A1 AFF1 NUDC PCCB KNL1	1.16e-03	1275	170	17	EFO_0004908
Disease	anemia (phenotype), response to ribavirin	CYP24A1 DNAH17	1.16e-03	9	170	2	EFO_0004272, GO_1901559
Disease	systemic scleroderma, rheumatoid arthritis, myositis, systemic lupus erythematosus	STAT4 RSBN1 GLS	1.37e-03	38	170	3	EFO_0000685, EFO_0000717, EFO_0000783, MONDO_0007915
Disease	Diamond-Blackfan anemia (implicated_via_orthology)	RPSA RPL18	1.44e-03	10	170	2	DOID:1339 (implicated_via_orthology)
Disease	myositis	PDE4D STAT4 RSBN1	1.47e-03	39	170	3	EFO_0000783
Disease	platelet component distribution width	SH3TC2 RIN3 LAMA5 C4orf54 TRPM3 EXOC3L4 ATAD2B SVIL TBC1D14 PPP1R9B ARHGEF3 XPO7	1.50e-03	755	170	12	EFO_0007984
Disease	cholesterol:total lipids ratio, low density lipoprotein cholesterol measurement	ABCA1 OGDH SYNE2 AFF1 NUDC	1.51e-03	144	170	5	EFO_0004611, EFO_0020943
Disease	neurodegenerative disease (implicated_via_orthology)	UBR2 PSMC1 GRIK1 OGDH MARK2	1.56e-03	145	170	5	DOID:1289 (implicated_via_orthology)
Disease	systemic juvenile idiopathic arthritis, polyarticular juvenile idiopathic arthritis, rheumatoid factor negative, oligoarticular juvenile idiopathic arthritis	STAT4 RSBN1 LNPEP	1.59e-03	40	170	3	EFO_1001999, EFO_1002019, EFO_1002020
Disease	C-reactive protein measurement	UBR2 ABCA1 DPYSL5 DYRK1A DGKH CEP192 ITGA1 VIT ST8SIA3 PTK7 RANBP17 LMX1B DNAH17 NUDC PCCB DNAH11	1.70e-03	1206	170	16	EFO_0004458
Disease	periodontitis	ABCA1 RPSA GRIK1 LNPK ARHGAP18 PARP15	1.91e-03	223	170	6	EFO_0000649
Disease	anxiety	B3GALT1 SATB2 DSCAM AS3MT DLST PCCB	1.91e-03	223	170	6	EFO_0005230
Disease	cortical surface area measurement	ALX3 CPAMD8 ITGA11 SATB2 RIN3 DPYSL5 DAPK1 RPSA ADGRV1 NHSL1 ATAD2B GLS XRN1 AFF1 PAPPA PPP1R9B DNAH11	2.04e-03	1345	170	17	EFO_0010736
Disease	Neurodevelopmental Disorders	DSCAM DYRK1A PTK7 LMX1B	2.08e-03	93	170	4	C1535926
Disease	biliary liver cirrhosis	SPEF2 STAT4 EXOC3L4	2.09e-03	44	170	3	EFO_0004267
Disease	microphthalmia (implicated_via_orthology)	GDF6 TRPM3	2.10e-03	12	170	2	DOID:10629 (implicated_via_orthology)
Disease	interleukin 13 measurement	B3GALT1 PDE4D DAPK1	2.23e-03	45	170	3	EFO_0008171
Disease	brain connectivity measurement	ITGA11 SATB2 DPYSL5 ADGRV1 SMIM21 NHSL1 TENM4 AFF1	2.32e-03	400	170	8	EFO_0005210
Disease	Hypercalcemia	CYP24A1 CASR	2.47e-03	13	170	2	C0020437
Disease	Milk-Alkali Syndrome	CYP24A1 CASR	2.47e-03	13	170	2	C0026141
Disease	HIV-1 infection	MCM8 DYRK1A ST8SIA3 GPC5	2.52e-03	98	170	4	EFO_0000180
Disease	opioid dependence	SPTBN2 ADGRV1 NHSL1 LMX1B PAPPA LNPK	2.59e-03	237	170	6	EFO_0005611
Disease	myopathy (implicated_via_orthology)	MYH3 MYH6 MYH15	2.69e-03	48	170	3	DOID:423 (implicated_via_orthology)
Disease	triacylglycerol 48:4 measurement	DSCAM TENM4	2.87e-03	14	170	2	EFO_0010407
Disease	Down syndrome (implicated_via_orthology)	DSCAM DYRK1A	3.30e-03	15	170	2	DOID:14250 (implicated_via_orthology)
Disease	Generalized hypotonia	TRPM3 LNPK	3.30e-03	15	170	2	C1858120
Disease	immature platelet count	TRPM3 EXOC3L4 TBC1D14 ARHGEF3	3.35e-03	106	170	4	EFO_0803544
Disease	anti-neutrophil antibody associated vasculitis	PABPC5 RSBN1 ARHGAP18	3.38e-03	52	170	3	EFO_0004826
Disease	interleukin 12 measurement	DYRK1A TENM4 SACS	3.56e-03	53	170	3	EFO_0004753
Disease	triglycerides in HDL measurement	ABCA1 AFF1 PCCB	3.56e-03	53	170	3	EFO_0022317
Disease	calcium measurement	GPR39 CYP24A1 CASR LMX1A SYNE2 RBPJ ABCC12 ARHGEF3 PCCB PARP15	3.61e-03	628	170	10	EFO_0004838
Disease	parathyroid hormone measurement	PDE4D CYP24A1 CASR	3.96e-03	55	170	3	EFO_0004752
Disease	triglycerides to total lipids in medium HDL percentage	AFF1 NUDC PCCB	4.16e-03	56	170	3	EFO_0022333
Disease	triglycerides in chylomicrons and extremely large VLDL measurement	AFF1 NUDC PCCB	4.16e-03	56	170	3	EFO_0022316
Disease	cholesteryl esters to total lipids in medium HDL percentage	AFF1 NUDC PCCB	4.16e-03	56	170	3	EFO_0022251
Disease	immature platelet fraction	TRPM3 EXOC3L4 TBC1D14 ARHGEF3	4.34e-03	114	170	4	EFO_0009187
Disease	triglycerides in IDL measurement	AFF1 NUDC PCCB	4.60e-03	58	170	3	EFO_0022149
Disease	Uterine leiomyoma, estrogen-receptor positive breast cancer	MCM8 ATAD5	4.75e-03	18	170	2	EFO_1000649, HP_0000131
Disease	caudal middle frontal gyrus volume measurement	FRY NSMAF	4.75e-03	18	170	2	EFO_0010290
Disease	phospholipids in VLDL measurement	AFF1 NUDC PCCB	4.82e-03	59	170	3	EFO_0022301
Disease	concentration of chylomicrons and extremely large VLDL particles measurement	AFF1 NUDC PCCB	4.82e-03	59	170	3	EFO_0022260
Disease	waist-hip ratio	CMKLR2 COL6A2 CPAMD8 ITGA11 ABCA1 CEP192 PTK7 LMX1A GLS DNAH17 SYNE2 RBPJ XRN1 PCCB KNL1	5.00e-03	1226	170	15	EFO_0004343
Disease	atrophic macular degeneration, age-related macular degeneration, wet macular degeneration	ABCA1 SPEF2 TRPM3	5.05e-03	60	170	3	EFO_0001365, EFO_0004683, EFO_1001492
Disease	emphysema pattern measurement	RIN3 SVIL	5.29e-03	19	170	2	EFO_0005850
Disease	free cholesterol in VLDL measurement	AFF1 NUDC PCCB	5.29e-03	61	170	3	EFO_0022276
Disease	cholesterol:total lipids ratio, intermediate density lipoprotein measurement	SYNE2 AFF1 NUDC PCCB	5.36e-03	121	170	4	EFO_0008595, EFO_0020943
Disease	lymphocyte percentage of leukocytes	UBR2 RIN3 ITGA1 FAM43B TRMU GTF3C1 LNPEP TBC1D14 AFF1 ARHGEF3	5.37e-03	665	170	10	EFO_0007993
Disease	systemic lupus erythematosus (is_implicated_in)	STAT4 C4A C4B	5.54e-03	62	170	3	DOID:9074 (is_implicated_in)
Disease	triglycerides in medium LDL measurement	ABCA1 AFF1 PCCB	5.54e-03	62	170	3	EFO_0022322
Disease	total lipids in chylomicrons and extremely large VLDL measurement	AFF1 NUDC PCCB	5.54e-03	62	170	3	EFO_0022306

Protein segments in the cluster

Peptide	Gene	Start	Entry
RQRKTEFFKSSTLFN	ATAD5	521	Q96QE3
FKIFEVNASSQRSGR	ATAD5	1151	Q96QE3
KKTRTRSTQQFRVFE	ERV3-1	241	Q14264
AFSRASQRALTQVSK	EXOC3L4	56	Q17RC7
FSNTSALAKDFIRRL	DAPK1	241	P53355
NVFSTNSFQLLTVKR	ERVK13-1	16	Q9NX77
KRFSQTLQRSISFRS	ARHGEF3	61	Q9NR81
SRAAFRLFETKITQV	C4B	1636	P0C0L5
SKKRRNRTTFSTFQL	ALX3	151	O95076
SSRSRVQVQKAFAGT	APOL6	211	Q9BWW8
FKVAARATLRRSNVS	CASR	881	P41180
LAFKFAVTSINRNRT	GRIK1	56	P39086
LASKRNAVAFRSFNS	MASTL	646	Q96GX5
NFNKSIVARLFSDAR	ABCA1	96	O95477
LTVARKNFTFGNIRT	B3GALT1	41	Q9Y5Z6
FRQGETNKSFIISAR	ADGRV1	1516	Q8WXG9
LRLVAAKAFTESARF	CFAP46	1006	Q8IYW2
RNLSRLTASFEKATA	DNAH11	3346	Q96DT5
QLTAFTFRKNLAATA	ABCA13	4526	Q86UQ4
FSFSNLIQAVTRRFS	ANPEP	896	P15144
VAQSFRSSKSSFLNR	DNHD1	2251	Q96M86
NTNFRGVSLNLTRKF	DYRK1A	251	Q13627
EAFVKRRNRNASASF	DNAJC2	36	Q99543
QFATKQLSRTLSRAT	DCAF16	146	Q9NXF7
NFVRFQLSTSIAALT	ATP2C1	701	P98194
RKQLSSQGTVRFFNS	MKRN2	361	Q9H000
SVKNRDRFTQNLSVF	RANBP17	1051	Q9H2T7
RRFERTLNKNVFTSA	EVA1A	101	Q9H8M9
SNIVLLTQAFRRKFV	GLS	206	O94925
IVLNFRTTFVSKSGQ	KCNH3	276	Q9ULD8
ALVNFQSNRRSISFV	OR8I2	81	Q8N0Y5
QAVLSRFFQSTGSLK	MSH3	21	P20585
IVNSTARTFNRKSGV	PARP15	321	Q460N3
SARRTEKIFLSTFQS	GPR39	401	O43194
STRFNKTKTFRINQL	LAMA3	2941	Q16787
SNRSTAKRFISALNN	MCM8	771	Q9UJA3
FQTICRQLRSSKFSV	MGME1	6	Q9BQP7
KSFQRTTLTFKRRFQ	FAM149A	756	A5PLN7
FLSQVSQDALRRTIF	TRMU	176	O75648
ISGSNFKTNRKTRFI	PNLIP	76	P16233
SFFKDRQRASAALQL	NLRP11	311	P59045
LKFLISRNAAAFQET	GPC5	96	P78333
LSRKNSSQARDIFAA	ENTPD8	131	Q5MY95
VSSFLRNVRANLTTK	GARIN4	526	Q8IYT1
SRKNRFESVNQSLLF	ATAD2B	171	Q9ULI0
QTALAAFSDFKRLQR	FAM43B	196	Q6ZT52
FKQNISCRVSFITRT	DUOX2	956	Q9NRD8
FSKIASNTQSRRTFI	CHI3L1	106	P36222
INFSSLSRQTKRLFR	NHSL1	26	Q5SYE7
ILTTQQRRAFKASFE	LMX1A	201	Q8TE12
FAQVLASLRSVRSNF	PDE4A	181	P27815
FAQVLASLRTVRNNF	PDE4D	226	Q08499
RNTAASTLGFRLQSK	CSNKA2IP	381	A0A1B0GTH6
RVGIFQSFQKSSRDI	DDX28	436	Q9NUL7
RTLNNQFASFIDKVR	KRT78	116	Q8N1N4
NTASFRKTAERLLRF	DSE	766	Q9UL01
GDNFRTQKLSFIIRT	LNPEP	916	Q9UIQ6
SRRVSFADTIKVFQT	KNL1	56	Q8NG31
RVNSNFRFSKTVAPA	ITGA11	141	Q9UKX5
FARISFDSQISTTKR	LAMA5	2951	O15230
ALKSAFRNQFSLVTA	PCDHGC4	396	Q9Y5F7
FSFSNLVSNIARRLF	PCDH11X	286	Q9BZA7
FFSLKTDRARQVTTI	PAPPA	171	Q13219
SRFFNLKLKNQTSER	MTPAP	146	Q9NVV4
KNANNSFTIITPFRR	DGKH	121	Q86XP1
QISRSFFSGTQERKV	ITGA1	731	P56199
FSALRFLVVTQKAAF	HUWE1	1236	Q7Z6Z7
SRQVALAVSKFLLAF	PTGDR2	201	Q9Y5Y4
ALRSTATFAQALQFV	UQCRC1	31	P31930
EKNRSFSNAARVLSR	NUP155	1086	O75694
RTRDRATFTNVFVKN	PABPC5	191	Q96DU9
LDINSSVKGARFVRF	PCCB	366	P05166
RKVVINNSVFSVRFF	DLST	46	P36957
KTFSQNRPAAARTFQ	OGDH	21	Q02218
ASTAAFFLLRNIRTK	SLC37A4	406	O43826
TIKQQTSLFIARSFR	CKAP5	411	Q14008
SKSRSLAAFLQQLRS	CYP24A1	6	Q07973
SLAFSRINSFFQRIQ	DNAH17	411	Q9UFH2
LSTFNLERTAFRKDS	FRMPD4	1076	Q14CM0
LTAFVLKSFAQARSF	CPAMD8	1211	Q8IZJ3
ASFIKNLQGISSFRR	COL6A2	116	P12110
VRTLKSFSTLANNFV	IL24	131	Q13007
TAAILKNSRFAQDFL	AS3MT	306	Q9HBK9
SKFTSKFVRRNLSFR	MARK2	636	Q7KZI7
SRTLKVNLRNNSFIT	CEP192	2456	Q8TEP8
RLARTSFDKNRFQNI	NSMAF	176	Q92636
SRQEKRVFNALSSTS	DUS4L	291	O95620
VLKSLFVNFTTQAER	FRY	66	Q5TBA9
VQSTFRKSLASLQSR	FAM186A	2331	A6NE01
TVKGIFLRSQNSAFR	C4orf54	931	D6RIA3
GTLFRLSFRTQQEAK	SACS	1641	Q9NZJ4
QAARATLLRAFQAKF	CFAP74	1181	Q9C0B2
SRAAFRLFETKITQV	C4A	1636	P0C0L4
NRFVAVTSSNAAKLL	DPYSL5	371	Q9BPU6
LNKARASRSSVQDFI	RIN3	866	Q8TB24
FATSQLSFLQKVSAR	MROH5	1301	Q6ZUA9
RSIFSNGSFIIRTVK	DSCAM	1336	O60469
ALLVVFTRSQRKNLF	GDF6	276	Q6KF10
VISSRNTGQRAVLKF	RPSA	76	P08865
RRNFLKTGTKFSNFI	RSBN1	346	Q5VWQ0
SRAIQALRSVLNAFS	SZT2	2061	Q5T011
ALRSVLNAFSVVNRK	SZT2	2066	Q5T011
RIFRSSDFAKNFVQT	SORT1	196	Q99523
LDSRVSSAKLNNFSR	SPEF2	51	Q9C093
FSRFKNRETIASVRS	POLR2D	71	O15514
KVSVAQLRSAFLASA	SVIL	591	O95425
KQFEISVSRSQSFRS	SYT16	196	Q17RD7
LLRNSSLQARVESFF	TMEM132C	71	Q8N3T6
FSRRVAEIQFLLQSS	SYNE2	1696	Q8WXH0
SVRDQAFKAIRSFLS	SCYL1	521	Q96KG9
TSRQFQRFVALKGDL	RGS22	1031	Q8NE09
TVVAVFQKSSNRLLA	MYH15	616	Q9Y2K3
FASVVAKTFNRLQRL	PKDREJ	1376	Q9NTG1
SVSQAVFARVAFNRT	SATB2	376	Q9UPW6
SRSAFKLIQLNRRFQ	FTSJ3	26	Q8IY81
SSNKEQRSAVFVILF	ST6GALNAC6	36	Q969X2
AFQRDVGRKTNLTTF	ST8SIA3	196	O43173
SIQSQRAQFLITFKT	SH3TC2	101	Q8TF17
TVRNDNSSRFGKFIR	MYH3	236	P11055
SSFRIAKQIFTRIST	MSH4	711	O15457
NSFATRLSNIFVIGK	RPS4X	216	P62701
AKAVANQTSATFLRV	PSMC1	236	P62191
TVRNDNSSRFGKFIR	MYH6	236	P13533
AKLNSAFRRSAILVT	ABCC12	281	Q96J65
QELVNTFFSFLRRKT	NUDC	26	Q9Y266
VRKTNNFSAFLANVR	SPC25	201	Q9HBM1
RSVFFNFIRNLLSET	AKAP3	591	O75969
TRKNKEFFARLSTNV	AFF1	1166	P51825
LISKKFQARFRSSVA	CMKLR2	306	P46091
REAFKTSSRNALNVS	CHST6	316	Q9GZX3
ARQNRFFTALKVVNL	C15orf61	101	A6NNL5
FLRNLSSASQATRQK	PKP3	481	Q9Y446
SNFFARNLLARKQSA	TBC1D14	236	Q9P2M4
NVLIVQLKRFSFRSF	USP19	1101	O94966
RIFQFQNFTNTRKSI	TSR1	526	Q2NL82
QKRLFLQFTTGTDRA	UBE3A	801	Q05086
ASSQEALQAARSFKR	TRAPPC11	711	Q7Z392
RFSRTKFTEFQTQAL	ZFHX2	1596	Q9C0A1
IVRRVFSSKRSNVNF	RALGAPA1	396	Q6GYQ0
ARRTNSTFNQVVLKR	RPL18	36	Q07020
TTQAKARSLFDANRA	SPTBN2	1371	O15020
VKDFLSQLRSSNRRF	RIPK3	301	Q9Y572
ASIDKNVSTLSNRRF	STAT4	361	Q14765
RRLSRTSAFQSFESK	TRPM3	1716	Q9HCF6
QKAFRFLSSLSIHQR	ZNF840P	241	A6NDX5
IRAFDSRFSNIKTLD	XRN1	836	Q8IZH2
KFIRIFQLSNNIRSV	USP29	46	Q9HBJ7
FRTVLQFVTNLTKEF	VIT	511	Q6UXI7
AVFLSDSNSRRVFKI	TENM4	1291	Q6N022
KTRNRTFSTLFLVVF	TMCC1	616	O94876
FLSTLTRTQAAAVQK	ARHGAP18	136	Q8N392
ANSIFRNFLRLKSSR	SMIM21	81	Q3B7S5
RKSDFSQIVLRALFT	SLC28A1	561	O00337
KVALFNRLRSQTVST	RBPJ	186	Q06330
FRSILSDKTSRNLFF	SLC30A7	26	Q8NEW0
RVFSLSSEFKNITVR	SNRNP200	1016	O75643
TSSAQFALRLLAFRQ	ZFR	1011	Q96KR1
RRSLFNNAERAKFLS	XPO7	291	Q9UIA9
LTKNRDRFTQNLSAF	XPO7	1051	Q9UIA9
IVLNKNRTIFRFNAA	SCN7A	81	Q01118
SSIRLFANKSRFSSE	XPNPEP2	271	O43895
LFGSAANVVSAKRNR	ZBED1	621	O96006
ILRFRAFQQSTAASL	TCTN3	361	Q6NUS6
RFRISNSSTANRVKT	GTF3C1	711	Q12789
LAAFVQRSTVLSKNR	UBR2	1126	Q8IWV8
SRFEVFKNGTLRINS	PTK7	456	Q13308
ASRNSTVSRLIFTFF	SERINC2	31	Q96SA4
ITDAFSSLAKRSNFR	VPS33B	471	Q9H267
AFTARFLAFLQATKA	TRPC3	471	Q13507
RLNLFTQSNSRVFES	TRPC3	736	Q13507
RQSTSFFKRSKVRQV	WNK3	1281	Q9BYP7
FGTASNIKSRVNRLS	ETF1	56	P62495
LTTQQRRAFKASFEV	LMX1B	226	O60663
RTVIIFFFSKRTERN	LNPK	91	Q9C0E8
FAAKFNLSVTDASRR	NARF	106	Q9UHQ1
TQSFAASVLRNTKGR	PPP1R9B	561	Q96SB3