Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNHD1 DNAH10 DNAH14 DNAH6 DYNC1H1

2.68e-07181635GO:0008569
GeneOntologyMolecularFunctionmicrotubule motor activity

DNHD1 DNAH10 DNAH14 KIF9 STARD9 DNAH6 DYNC1H1

1.65e-06701637GO:0003777
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNHD1 DNAH10 DNAH14 DNAH6 DYNC1H1

2.88e-06281635GO:0051959
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNHD1 DNAH10 DNAH14 DNAH6 DYNC1H1

1.20e-05371635GO:0045505
GeneOntologyMolecularFunctionATP-dependent activity

DNHD1 ABCF1 DNAH10 ACSF2 ABCA10 ABCA8 DNAH14 KIF9 ABCA5 STARD9 ABCD4 UBA6 NAV2 DNAH6 DYNC1H1 ATP5F1C

4.46e-0561416316GO:0140657
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

ZNF131 GCM2 ZNF337 ZNF268 ZNF674 ZNF683 ZBTB26 SIM1 ZNF236 ZNF416 ZNF512B ZNF708 ZNF594 ZNF600 SALL1 GZF1 ZNF530 ZNF517 ZNF253 ZNF814 ZNF552 ZNF81 ZNF615 ZNF614 HDAC1 MYBL1 ZNF574

5.11e-05145916327GO:0000977
GeneOntologyMolecularFunctioncytoskeletal motor activity

DNHD1 DNAH10 DNAH14 KIF9 STARD9 DNAH6 DYNC1H1

5.24e-051181637GO:0003774
GeneOntologyMolecularFunctionpropionyl-CoA carboxylase activity

PCCA PCCB

6.62e-0521632GO:0004658
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

ZNF131 GCM2 ZNF337 ZNF268 ZNF674 ZBTB26 SIM1 ZNF236 ZNF416 ZNF512B ZNF708 ZNF594 ZNF600 SALL1 GZF1 ZNF530 ZNF517 ZNF253 ZNF814 ZNF552 ZNF81 ZNF615 ZNF614 MYBL1 ZNF574

2.00e-04141216325GO:0000981
GeneOntologyMolecularFunctionABC-type transporter activity

ABCA10 ABCA8 ABCA5 ABCD4

6.81e-04491634GO:0140359
GeneOntologyMolecularFunctionCoA carboxylase activity

PCCA PCCB

9.72e-0461632GO:0016421
GeneOntologyMolecularFunctionATP hydrolysis activity

ABCF1 DNAH10 ABCA10 ABCA8 KIF9 ABCA5 ABCD4 NAV2 DNAH6 DYNC1H1 ATP5F1C

1.02e-0344116311GO:0016887
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

ZNF131 GCM2 ZNF268 ZNF683 ZBTB26 ZNF236 ZNF416 ZNF708 ZNF594 ZNF600 SALL1 GZF1 ZNF530 ZNF253 ZNF814 ZNF552 ZNF81 ZNF615 HDAC1 MYBL1 ZNF574

1.24e-03124416321GO:0000978
GeneOntologyMolecularFunctionfibroblast growth factor binding

RPS2 FIBP FGFR2

1.35e-03271633GO:0017134
GeneOntologyMolecularFunctionligase activity, forming carbon-carbon bonds

PCCA PCCB

1.35e-0371632GO:0016885
GeneOntologyBiologicalProcesscilium movement

CFAP47 DNHD1 DNAH10 DNAH14 MET KIF9 RABL2B RABL2A DNAH6 HYDIN DYNC1H1

8.05e-0626116411GO:0003341
GeneOntologyBiologicalProcessestablishment of planar polarity

WNT9B BRSK2 DLG3 WDR1 BRSK1

2.53e-05441645GO:0001736
GeneOntologyBiologicalProcessmorphogenesis of a polarized epithelium

WNT9B BRSK2 DLG3 CTNND1 WDR1 BRSK1

2.53e-05731646GO:0001738
GeneOntologyBiologicalProcessestablishment of tissue polarity

WNT9B BRSK2 DLG3 WDR1 BRSK1

2.82e-05451645GO:0007164
GeneOntologyBiologicalProcesscilium movement involved in cell motility

CFAP47 DNHD1 DNAH10 DNAH14 MET KIF9 RABL2B RABL2A DNAH6

4.80e-052101649GO:0060294
GeneOntologyBiologicalProcesscilium-dependent cell motility

CFAP47 DNHD1 DNAH10 DNAH14 MET KIF9 RABL2B RABL2A DNAH6

5.76e-052151649GO:0060285
GeneOntologyBiologicalProcesscilium or flagellum-dependent cell motility

CFAP47 DNHD1 DNAH10 DNAH14 MET KIF9 RABL2B RABL2A DNAH6

5.76e-052151649GO:0001539
GeneOntologyCellularComponentinner dynein arm

DNHD1 DNAH10 DNAH6

5.27e-05101623GO:0036156
GeneOntologyCellularComponentdynein complex

DNHD1 DNAH10 DNAH14 DNAH6 DYNC1H1

6.12e-05541625GO:0030286
GeneOntologyCellularComponent9+2 motile cilium

DNHD1 DNAH10 DNAH14 MET KIF9 RABL2B RABL2A IL4I1 DNAH6

1.03e-042381629GO:0097729
GeneOntologyCellularComponentmotile cilium

CFAP47 DNHD1 DNAH10 DNAH14 MET KIF9 RABL2B RABL2A IL4I1 DNAH6

4.64e-0435516210GO:0031514
GeneOntologyCellularComponentintraciliary transport particle B

TRIM59 RABL2B RABL2A

5.48e-04211623GO:0030992
DomainZnf_C2H2-like

ZNF131 ZNF337 ZNF268 ZNF674 ZNF683 ZBTB26 ZNF285 ZNF236 ZNF416 ZNF512B YOD1 ZNF708 ZNF594 ZNF600 SALL1 GZF1 ZNF530 ZNF517 ZNF253 ZNF638 ZNF814 ZNF552 ZNF81 ZNF615 ZNF614 ZNF574

6.07e-0979616326IPR015880
DomainZnf_C2H2

ZNF131 ZNF337 ZNF268 ZNF674 ZNF683 ZBTB26 ZNF285 ZNF236 ZNF416 ZNF512B YOD1 ZNF708 ZNF594 ZNF600 SALL1 GZF1 ZNF530 ZNF517 ZNF253 ZNF638 ZNF814 ZNF552 ZNF81 ZNF615 ZNF614 ZNF574

7.64e-0980516326IPR007087
DomainZnF_C2H2

ZNF131 ZNF337 ZNF268 ZNF674 ZNF683 ZBTB26 ZNF285 ZNF236 ZNF416 ZNF512B YOD1 ZNF708 ZNF594 ZNF600 SALL1 GZF1 ZNF530 ZNF517 ZNF253 ZNF638 ZNF814 ZNF552 ZNF81 ZNF615 ZNF614 ZNF574

8.25e-0980816326SM00355
DomainZINC_FINGER_C2H2_2

ZNF131 ZNF337 ZNF268 ZNF674 ZNF683 ZBTB26 ZNF285 ZNF236 ZNF416 ZNF512B YOD1 ZNF708 ZNF594 ZNF600 SALL1 GZF1 ZNF530 ZNF517 ZNF253 ZNF814 ZNF552 ZNF81 ZNF615 ZNF614 ZNF574

1.58e-0877516325PS50157
DomainZINC_FINGER_C2H2_1

ZNF131 ZNF337 ZNF268 ZNF674 ZNF683 ZBTB26 ZNF285 ZNF236 ZNF416 ZNF512B YOD1 ZNF708 ZNF594 ZNF600 SALL1 GZF1 ZNF530 ZNF517 ZNF253 ZNF814 ZNF552 ZNF81 ZNF615 ZNF614 ZNF574

1.66e-0877716325PS00028
Domain-

ZNF131 ZNF337 ZNF268 ZNF674 ZNF683 ZBTB26 ZNF285 ZNF236 ZNF416 ZNF708 ZNF594 ZNF600 SALL1 GZF1 ZNF530 ZNF517 ZNF253 ZNF814 ZNF552 ZNF81 ZNF615 ZNF614 ZNF574

2.59e-08679163233.30.160.60
Domainzf-C2H2

ZNF131 ZNF337 ZNF268 ZNF674 ZNF683 ZBTB26 ZNF285 ZNF236 ZNF416 ZNF708 ZNF594 ZNF600 SALL1 GZF1 ZNF530 ZNF517 ZNF253 ZNF814 ZNF552 ZNF81 ZNF615 ZNF614 ZNF574

3.77e-0869316323PF00096
DomainZnf_C2H2/integrase_DNA-bd

ZNF131 ZNF337 ZNF268 ZNF674 ZNF683 ZBTB26 ZNF285 ZNF236 ZNF416 ZNF708 ZNF594 ZNF600 SALL1 GZF1 ZNF530 ZNF517 ZNF253 ZNF814 ZNF552 ZNF81 ZNF615 ZNF614 ZNF574

3.87e-0869416323IPR013087
DomainDynein_HC_stalk

DNHD1 DNAH10 DNAH14 DNAH6 DYNC1H1

8.94e-08141635IPR024743
DomainMT

DNHD1 DNAH10 DNAH14 DNAH6 DYNC1H1

8.94e-08141635PF12777
DomainDHC_fam

DNHD1 DNAH10 DNAH14 DNAH6 DYNC1H1

1.33e-07151635IPR026983
DomainDynein_heavy

DNHD1 DNAH10 DNAH14 DNAH6 DYNC1H1

1.33e-07151635PF03028
DomainDynein_heavy_dom

DNHD1 DNAH10 DNAH14 DNAH6 DYNC1H1

1.33e-07151635IPR004273
DomainKRAB

ZNF337 ZNF268 ZNF674 ZNF285 ZNF416 ZNF708 ZNF530 ZNF517 ZNF253 ZNF814 ZNF552 ZNF81 ZNF615 ZNF614

3.22e-0635816314PS50805
DomainKRAB

ZNF337 ZNF268 ZNF674 ZNF285 ZNF416 ZNF708 ZNF530 ZNF517 ZNF253 ZNF814 ZNF552 ZNF81 ZNF615 ZNF614

3.22e-0635816314PF01352
DomainKRAB

ZNF337 ZNF268 ZNF674 ZNF285 ZNF416 ZNF708 ZNF530 ZNF517 ZNF253 ZNF814 ZNF552 ZNF81 ZNF615 ZNF614

4.56e-0636916314SM00349
DomainKRAB

ZNF337 ZNF268 ZNF674 ZNF285 ZNF416 ZNF708 ZNF530 ZNF517 ZNF253 ZNF814 ZNF552 ZNF81 ZNF615 ZNF614

4.70e-0637016314IPR001909
DomainP-loop_NTPase

DNHD1 ABCF1 DNAH10 MFHAS1 RAB14 ABCA10 ABCA8 DNAH14 ARL4C KIF9 RABL2B NWD2 RABL2A ABCA5 STARD9 ABCD4 NAV2 UCK2 DLG3 DNAH6 HYDIN DYNC1H1

4.72e-0684816322IPR027417
DomainAAA

ABCF1 DNAH10 ABCA10 ABCA8 ABCA5 ABCD4 NAV2 DNAH6 DYNC1H1

4.90e-061441639SM00382
DomainAAA+_ATPase

ABCF1 DNAH10 ABCA10 ABCA8 ABCA5 ABCD4 NAV2 DNAH6 DYNC1H1

4.90e-061441639IPR003593
DomainDynein_heavy_chain_D4_dom

DNAH10 DNAH14 DNAH6 DYNC1H1

5.23e-06141634IPR024317
DomainDynein_heavy_dom-2

DNHD1 DNAH10 DNAH6 DYNC1H1

5.23e-06141634IPR013602
DomainDHC_N2

DNHD1 DNAH10 DNAH6 DYNC1H1

5.23e-06141634PF08393
DomainAAA_8

DNAH10 DNAH14 DNAH6 DYNC1H1

5.23e-06141634PF12780
Domain-

DNHD1 ABCF1 DNAH10 MFHAS1 RAB14 ABCA10 ABCA8 DNAH14 ARL4C RABL2B NWD2 RABL2A ABCA5 ABCD4 NAV2 UCK2 DLG3 DNAH6 HYDIN DYNC1H1

8.22e-06746163203.40.50.300
DomainABC_tran

ABCF1 ABCA10 ABCA8 ABCA5 ABCD4

6.02e-05481635PF00005
DomainABC_TRANSPORTER_2

ABCF1 ABCA10 ABCA8 ABCA5 ABCD4

6.02e-05481635PS50893
DomainABC_TRANSPORTER_1

ABCF1 ABCA10 ABCA8 ABCA5 ABCD4

6.66e-05491635PS00211
DomainABC_transporter-like

ABCF1 ABCA10 ABCA8 ABCA5 ABCD4

7.35e-05501635IPR003439
DomainABC_A

ABCA10 ABCA8 ABCA5

1.36e-04121633IPR026082
DomainWD40_repeat

FBXW10B FBXW10 NBEA WDR5 EDC4 PAAF1 NWD2 SCAP HERC2 WDR1

1.42e-0427216310IPR001680
Domain-

FBXW10B FBXW10 NBEA WDR5 EDC4 PAAF1 SEMA3A MET NWD2 SCAP WDR1

1.69e-04333163112.130.10.10
DomainWD_REPEATS_1

FBXW10B FBXW10 NBEA WDR5 EDC4 PAAF1 NWD2 SCAP HERC2 WDR1

1.69e-0427816310PS00678
DomainWD_REPEATS_2

FBXW10B FBXW10 NBEA WDR5 EDC4 PAAF1 NWD2 SCAP HERC2 WDR1

1.74e-0427916310PS50082
DomainWD_REPEATS_REGION

FBXW10B FBXW10 NBEA WDR5 EDC4 PAAF1 NWD2 SCAP HERC2 WDR1

1.74e-0427916310PS50294
DomainWD40/YVTN_repeat-like_dom

FBXW10B FBXW10 NBEA WDR5 EDC4 PAAF1 SEMA3A MET NWD2 SCAP WDR1

1.78e-0433516311IPR015943
DomainATPase_dyneun-rel_AAA

DNAH10 DNAH6 DYNC1H1

2.21e-04141633IPR011704
DomainAAA_5

DNAH10 DNAH6 DYNC1H1

2.21e-04141633PF07728
DomainLAM_G_DOMAIN

HSPG2 COL27A1 NRXN1 USH2A

3.27e-04381634PS50025
DomainABC_transporter_CS

ABCF1 ABCA10 ABCA5 ABCD4

4.83e-04421634IPR017871
DomainWD40

FBXW10B FBXW10 NBEA WDR5 EDC4 PAAF1 NWD2 SCAP WDR1

5.91e-042681639SM00320
DomainWD40_repeat_CS

FBXW10B FBXW10 WDR5 PAAF1 NWD2 SCAP WDR1

6.00e-041641637IPR019775
DomainG-protein_beta_WD-40_rep

FBXW10B FBXW10 WDR5 PAAF1 WDR1

8.90e-04851635IPR020472
DomainMg_trans_NIPA

NIPAL1 NIPA2

1.11e-0361632IPR008521
DomainMg_trans_NIPA

NIPAL1 NIPA2

1.11e-0361632PF05653
DomainUmuC

POLH ESCO2

1.11e-0361632IPR001126
DomainWD40_repeat_dom

FBXW10B FBXW10 NBEA WDR5 EDC4 PAAF1 NWD2 SCAP WDR1

1.22e-032971639IPR017986
DomainAPC_su10/DOC_dom

MYCBP2 HERC2

1.54e-0371632IPR004939
DomainDOC

MYCBP2 HERC2

1.54e-0371632PS51284
DomainANAPC10

MYCBP2 HERC2

1.54e-0371632PF03256
DomainAPC10

MYCBP2 HERC2

1.54e-0371632SM01337
DomainLaminin_G

HSPG2 COL27A1 NRXN1 USH2A

1.64e-03581634IPR001791
Domainzf-C2H2_6

ZNF236 ZNF416 ZNF600 GZF1 ZNF530 ZNF253 ZNF814 ZNF615 ZNF574

1.79e-033141639PF13912
DomainDHC_N1

DNAH10 DYNC1H1

2.05e-0381632PF08385
DomainDynein_heavy_dom-1

DNAH10 DYNC1H1

2.05e-0381632IPR013594
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

CFAP47 POLR2A OR52L1 RPS16 NBEA ZBTB26 SLC25A16 FAM186B DSCAML1 DNAH14 DARS2 SLC5A2 YOD1 AGL ARHGAP20 DYNC1H1 HDAC1

9.27e-087361651729676528
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

ABCF1 ANK3 TRIM4 MYCBP2 RPS2 ACO2 POLR2A RPS16 EDC4 RAB14 WDR1 BRSK1 PCCA PCCB HYDIN DYNC1H1 ATP5F1C

3.38e-078071651730575818
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

ANK3 RPS2 RPS16 NBEA RAB14 MET ARL4C IGF2R ZNF638 DLG3 CTNND1 PCCA TASOR PCCB DYNC1H1 ATP5F1C

1.03e-067771651635844135
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

DNHD1 ABCF1 DNAH10 TRIM4 RPS2 ACO2 POLR2A RPS16 WDR5 EDC4 ANKHD1 DARS2 SLC5A2 IPO9 IGF2R STARD9 UBA6 CTNND1 FHL1 DYNC1H1 HDAC1 ATP5F1C

1.18e-0614251652230948266
Pubmed

Phosphorylation of microtubule-associated protein tau by AMPK-related kinases.

BRSK2 MELK BRSK1

2.08e-066165321985311
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

CADM3 AHCYL1 ABCF1 ANK3 MYCBP2 RPS2 ACO2 BRSK2 NBEA WDR5 EDC4 TBC1D24 MET NRXN1 DLG3 CTNND1 FHL1 PCCA PCCB

2.20e-0611391651936417873
Pubmed

Human transcription factor protein interaction networks.

ZNF131 HSPG2 NEPRO AHCYL1 DNAH10 ACO2 POLH MRPS18C WDR5 EDC4 ANKHD1 ZNF512B SALL1 ZNF638 HERC2 WDR1 FHL1 PCCA PCCB DYNC1H1 ATP5F1C

4.52e-0614291652135140242
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

AHCYL1 ABCF1 VWF ANK3 RPS2 ACO2 BRSK2 RPS16 NBEA EDC4 RAB14 TBC1D24 NWD2 DLG3 CTNND1 WDR1 BRSK1 FHL1 DNAH6 DYNC1H1 ATP5F1C

4.61e-0614311652137142655
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

HSPG2 MYCBP2 CTC1 MFHAS1 POLR2A EDC4 ZNF236 ANKHD1 DUS1L TBC1D24 SCAP IGF2R NAV2 DTX2 FGFR2 HERC2 ZNF614 DYNC1H1

5.74e-0611051651835748872
Pubmed

Fas ligand enhances malignant behavior of tumor cells through interaction with Met, hepatocyte growth factor receptor, in lipid rafts.

FASLG MET

2.24e-052165222535954
Pubmed

Hepatocyte growth factor (HGF), keratinocyte growth factor (KGF), and their receptors in human breast cells and tissues: alternative receptors.

MET FGFR2

2.24e-05216527866434
Pubmed

Overview of mutations in the PCCA and PCCB genes causing propionic acidemia.

PCCA PCCB

2.24e-052165210502773
Pubmed

RABL2 Is Required for Hepatic Fatty Acid Homeostasis and Its Dysfunction Leads to Steatosis and a Diabetes-Like State.

RABL2B RABL2A

2.24e-052165227732084
Pubmed

Correction of the metabolic defect in propionic acidemia fibroblasts by microinjection of a full-length cDNA or RNA transcript encoding the propionyl-CoA carboxylase beta subunit.

PCCA PCCB

2.24e-05216528188292
Pubmed

Mutation spectrum of the PCCA and PCCB genes in Japanese patients with propionic acidemia.

PCCA PCCB

2.24e-052165215059621
Pubmed

Hormone-dependent effects of FGFR2 and MAP3K1 in breast cancer susceptibility in a population-based sample of post-menopausal African-American and European-American women.

MAP3K1 FGFR2

2.24e-052165219028704
Pubmed

Identification of predicted human outer dynein arm genes: candidates for primary ciliary dyskinesia genes.

DNAH10 DNAH6

2.24e-052165215937072
Pubmed

Isolation of cDNA clones coding for the alpha and beta chains of human propionyl-CoA carboxylase: chromosomal assignments and DNA polymorphisms associated with PCCA and PCCB genes.

PCCA PCCB

2.24e-05216523460076
Pubmed

Propionic acidemia: identification of twenty-four novel mutations in Europe and North America.

PCCA PCCB

2.24e-052165212559849
Pubmed

[Analysis of PCCA and PCCB gene mutations in patients with propionic acidemia].

PCCA PCCB

2.24e-052165225636094
Pubmed

Analysis of relative gene dosage and expression differences of the paralogs RABL2A and RABL2B by Pyrosequencing.

RABL2B RABL2A

2.24e-052165220138207
Pubmed

M-COPA, a Golgi Disruptor, Inhibits Cell Surface Expression of MET Protein and Exhibits Antitumor Activity against MET-Addicted Gastric Cancers.

MET FGFR2

2.24e-052165227197184
Pubmed

Propionic Acidemia

PCCA PCCB

2.24e-052165222593918
Pubmed

Functional Analysis of the PCCA and PCCB Gene Variants Predicted to Affect Splicing.

PCCA PCCB

2.24e-052165233923806
Pubmed

c-Met activation in medulloblastoma induces tissue factor expression and activity: effects on cell migration.

F3 MET

2.24e-052165219359592
Pubmed

Effect of PCCB gene mutations on the heteromeric and homomeric assembly of propionyl-CoA carboxylase.

PCCA PCCB

2.24e-052165211749052
Pubmed

Identification of 34 novel mutations in propionic acidemia: Functional characterization of missense variants and phenotype associations.

PCCA PCCB

2.24e-052165230274917
Pubmed

Isozyme-Specific Role of SAD-A in Neuronal Migration During Development of Cerebral Cortex.

BRSK2 BRSK1

2.24e-052165230307479
Pubmed

Synapse associated protein 102 (SAP102) binds the C-terminal part of the scaffolding protein neurobeachin.

NBEA DLG3

2.24e-052165222745750
Pubmed

Genetic variants in FGFR2 and MAP3K1 are associated with the risk of familial and early-onset breast cancer in a South-American population.

MAP3K1 FGFR2

2.24e-052165223225170
Pubmed

Testis-enriched kinesin KIF9 is important for progressive motility in mouse spermatozoa.

KIF9 HYDIN

2.24e-052165232072696
Pubmed

Two frequent mutations associated with the classic form of propionic acidemia in Taiwan.

PCCA PCCB

2.24e-052165224863100
Pubmed

Isolation and characterization of propionyl-CoA carboxylase from normal human liver. Evidence for a protomeric tetramer of nonidentical subunits.

PCCA PCCB

2.24e-05216526765947
Pubmed

FBXW10 promotes hepatocarcinogenesis in male patients and mice.

FBXW10B FBXW10

2.24e-052165231400758
Pubmed

New splicing mutations in propionic acidemia.

PCCA PCCB

2.24e-052165217051315
Pubmed

Two novel human RAB genes with near identical sequence each map to a telomere-associated region: the subtelomeric region of 22q13.3 and the ancestral telomere band 2q13.

RABL2B RABL2A

2.24e-052165210444334
Pubmed

Elevated FBXW10 drives hepatocellular carcinoma tumorigenesis via AR-VRK2 phosphorylation-dependent GAPDH ubiquitination in male transgenic mice.

FBXW10B FBXW10

2.24e-052165237450367
Pubmed

SAD: a presynaptic kinase associated with synaptic vesicles and the active zone cytomatrix that regulates neurotransmitter release.

BRSK2 BRSK1

2.24e-052165216630837
Pubmed

Variants in RABL2A causing male infertility and ciliopathy.

RABL2B RABL2A

2.24e-052165233075816
Pubmed

Seventeen Novel Mutations in PCCA and PCCB Genes in Indian Propionic Acidemia Patients, and Their Outcomes.

PCCA PCCB

2.24e-052165227227689
Pubmed

Crystal structure of the alpha(6)beta(6) holoenzyme of propionyl-coenzyme A carboxylase.

PCCA PCCB

2.24e-052165220725044
Pubmed

Novel breast cancer risk alleles and endometrial cancer risk.

MAP3K1 FGFR2

2.24e-052165218785201
Pubmed

RABL2 positively controls localization of GPCRs in mammalian primary cilia.

RABL2B RABL2A

2.24e-052165230578315
Pubmed

Propionyl-CoA carboxylase - A review.

PCCA PCCB

2.24e-052165229033250
Pubmed

Functional characterization of tissue factor in von Willebrand factor-dependent thrombus formation under whole blood flow conditions.

VWF F3

2.24e-052165227562418
Pubmed

Investigating the regulation of brain-specific kinases 1 and 2 by phosphorylation.

BRSK2 BRSK1

2.24e-052165218339622
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

AHCYL1 ABCF1 MYCBP2 RPS2 ACO2 POLR2A RPS16 WDR5 RRM1 ANKHD1 MELK IPO9 ZNF638 HERC2 CTNND1 WDR1 RIOK2 DYNC1H1 ATP5F1C

2.49e-0513531651929467282
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

BDP1 ABCF1 ANK3 POLR2A NBEA UBA6 NAV2 WNT10A CTNND1 HYDIN KDM4B

2.78e-054971651136774506
Pubmed

Histone demethylase JMJD2B coordinates H3K4/H3K9 methylation and promotes hormonally responsive breast carcinogenesis.

WDR5 KDM4B HDAC1

2.90e-0513165321502505
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH10 DNAH6 DYNC1H1

3.67e-051416539373155
Pubmed

BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.

ABCF1 RPS2 ACO2 RPS16 WDR5 EDC4 RAB14 ANKHD1 RETSAT CTNND1 DYNC1H1 HDAC1 ATP5F1C

3.79e-057111651333022573
Pubmed

Expression of caspase family and muscle- and apoptosis-specific genes during skeletal myogenesis in mouse embryo.

CASP5 CASP6 FASLG

4.58e-0515165319801895
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

ANK3 MYCBP2 PAK5 NBEA EDC4 RAB14 IGF2R NRXN1 UBA6 DLG3 HERC2 CTNND1 WDR1 BRSK1 DYNC1H1

5.94e-059631651528671696
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

NBEA DSCAML1 NWD2 NRXN1 CTNND1

6.11e-0587165512465718
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

ANK3 CTC1 TMEM254 CUBN RAB14 ANKHD1 TRIM59 ESCO2 ZNF600 SCAP IGF2R TYW1B DDHD1 ZNF638 DTX2 TASOR

6.31e-0510841651611544199
Pubmed

Identification and expression of potential regulators of the mammalian mitotic-to-meiotic transition.

ESCO2 UBA6

6.69e-053165220826732
Pubmed

KIF16B/Rab14 molecular motor complex is critical for early embryonic development by transporting FGF receptor.

RAB14 FGFR2

6.69e-053165221238925
Pubmed

Inter-relationships of indices of endothelial damage/dysfunction [circulating endothelial cells, von Willebrand factor and flow-mediated dilatation] to tissue factor and interleukin-6 in acute coronary syndromes.

VWF F3

6.69e-053165216324758
Pubmed

FGFR2, HER2 and cMet in gastric adenocarcinoma: detection, prognostic significance and assessment of downstream pathway activation.

MET FGFR2

6.69e-053165224306956
Pubmed

Matrilysin/MMP-7 Cleavage of Perlecan/HSPG2 Complexed with Semaphorin 3A Supports FAK-Mediated Stromal Invasion by Prostate Cancer Cells.

HSPG2 SEMA3A

6.69e-053165229740048
Pubmed

Synapses of amphids defective (SAD-A) kinase promotes glucose-stimulated insulin secretion through activation of p21-activated kinase (PAK1) in pancreatic β-Cells.

BRSK2 BRSK1

6.69e-053165222669945
Pubmed

HER2, MET and FGFR2 oncogenic driver alterations define distinct molecular segments for targeted therapies in gastric carcinoma.

MET FGFR2

6.69e-053165224518603
Pubmed

p120-catenin is a binding partner and substrate for Group B Pak kinases.

PAK5 CTNND1

6.69e-053165220564219
Pubmed

Breast cancer susceptibility alleles and ovarian cancer risk in 2 study populations.

MAP3K1 FGFR2

6.69e-053165218973230
Pubmed

Efficacy of simvastatin or ezetimibe on tissue factor, von Willebrand's factor and C-reactive protein in patients with hypercholesterolaemia.

VWF F3

6.69e-053165220142117
Pubmed

Targeting FGFR Pathway in Human Hepatocellular Carcinoma: Expressing pFGFR and pMET for Antitumor Activity.

MET FGFR2

6.69e-053165226351320
Pubmed

Lnc-C/EBPβ Modulates Differentiation of MDSCs Through Downregulating IL4i1 With C/EBPβ LIP and WDR5.

WDR5 IL4I1

6.69e-053165231379854
Pubmed

Persistence of the cell-cycle checkpoint kinase Wee1 in SadA- and SadB-deficient neurons disrupts neuronal polarity.

BRSK2 BRSK1

6.69e-053165220026642
Pubmed

Establishment of patient-derived gastric cancer xenografts: a useful tool for preclinical evaluation of targeted therapies involving alterations in HER-2, MET and FGFR2 signaling pathways.

MET FGFR2

6.69e-053165228292264
Pubmed

Microtubule stabilization specifies initial neuronal polarization.

BRSK2 BRSK1

6.69e-053165218268107
Pubmed

Tissue factor: A potent stimulator of Von Willebrand factor synthesis by human umbilical vein endothelial cells.

VWF F3

6.69e-053165227766025
Pubmed

Developmental expression of PAM (protein associated with MYC) in the rodent brain.

MYCBP2 ADCY1

6.69e-053165212036515
Pubmed

Association of single nucleotide polymorphisms in FGF-RAS/MAP signalling cascade with breast cancer susceptibility.

MAP3K1 FGFR2

6.69e-053165229372690
Pubmed

Functional characterization of NIPA2, a selective Mg2+ transporter.

NIPAL1 NIPA2

6.69e-053165218667602
Pubmed

Variation in Cilia Protein Genes and Progression of Lung Disease in Cystic Fibrosis.

DNAH14 DNAH6

6.69e-053165229323929
Pubmed

Association Study Confirmed Three Breast Cancer-Specific Molecular Subtype-Associated Susceptibility Loci in Chinese Han Women.

MAP3K1 FGFR2

6.69e-053165228408616
Pubmed

Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.

FBXW10B VWF ELP5 CTC1 POLR2A MELTF ZNF517 NAV2 HERC2 KDM4B ATP5F1C

7.12e-055521651110737800
Pubmed

Multiple mouse chromosomal loci for dynein-based motility.

DNAH14 MET DNAH6 DYNC1H1

7.43e-054716548812413
Pubmed

Transcriptional regulation of a metastasis suppressor gene by Tip60 and beta-catenin complexes.

POLR2A MAP3K1 HDAC1

8.12e-0518165315829968
Pubmed

Charting the landscape of tandem BRCT domain-mediated protein interactions.

DNHD1 AHCYL1 POLR2A MRPS18C WDR5 CUBN TRAPPC8 MAP3K1 IPO9 DTX2 USH2A DYNC1H1

9.20e-056701651222990118
Pubmed

Evolution of the regulators of G-protein signaling multigene family in mouse and human.

WNT9B FASLG FGFR2 MYBL1

1.03e-0451165411829488
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

ABCF1 MYCBP2 RPS2 POLR2A EDC4 RAB14 ZNF512B IGF2R UBA6 ZNF638 UCK2 HERC2 CTNND1 DYNC1H1 ATP5F1C

1.17e-0410241651524711643
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

ABCF1 PAK5 BRSK2 RETSAT TRIM59 DARS2 MAP3K1 MET FIBP FGFR2 CTNND1 BRSK1 RIOK2 HDAC1

1.20e-049101651436736316
Pubmed

Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristics.

MAP3K1 FGFR2

1.33e-044165218437204
Pubmed

Pax-3 is necessary for migration but not differentiation of limb muscle precursors in the mouse.

SIM1 MET

1.33e-04416528631247
Pubmed

Loss of NECL1, a novel tumor suppressor, can be restored in glioma by HDAC inhibitor-Trichostatin A through Sp1 binding site.

CADM3 HDAC1

1.33e-044165219062177
Pubmed

Distribution of FGFR2, TNRC9, MAP3K1, LSP1, and 8q24 alleles in genetically enriched breast cancer patients versus elderly tumor-free women.

MAP3K1 FGFR2

1.33e-044165220417875
Pubmed

Acute digoxin loading reduces ABCA8A mRNA expression in the mouse liver.

ABCA8 ABCA5

1.33e-044165216445568
Pubmed

Hepatocyte growth factor receptor tyrosine kinase met is a substrate of the receptor protein-tyrosine phosphatase DEP-1.

MET CTNND1

1.33e-044165212475979
Pubmed

Mitochondrial targeting signals and mature peptides of 3-methylcrotonyl-CoA carboxylase.

PCCA PCCB

1.33e-044165216023992
Pubmed

Clinical correlates of low-risk variants in FGFR2, TNRC9, MAP3K1, LSP1 and 8q24 in a Dutch cohort of incident breast cancer cases.

MAP3K1 FGFR2

1.33e-044165217997823
Pubmed

Identification, tissue specific expression, and chromosomal localisation of several human dynein heavy chain genes.

DNAH10 DNAH6

1.33e-044165211175280
Pubmed

Tuberous sclerosis complex proteins control axon formation.

BRSK2 BRSK1

1.33e-044165218794346
Pubmed

NF-kappaB p50 promotes HIV latency through HDAC recruitment and repression of transcriptional initiation.

POLR2A HDAC1

1.33e-044165216319923
Pubmed

Sall1-dependent signals affect Wnt signaling and ureter tip fate to initiate kidney development.

WNT9B SALL1

1.33e-044165220702564
Pubmed

Hepatocyte and keratinocyte growth factors and their receptors in human lung emphysema.

MET FGFR2

1.33e-044165216216128
Pubmed

Genome-wide ENU mutagenesis to reveal immune regulators.

RABL2B RABL2A

1.33e-044165211567631
Pubmed

Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

BDP1 PAK5 ZNF512B NWD2 DLG3

1.36e-04103165510574462
Pubmed

Proteomic Analysis of the Spinophilin Interactome in Rodent Striatum Following Psychostimulant Sensitization.

AHCYL1 ANK3 ACO2 RPS16 RAB14 DLG3 WDR1 DYNC1H1 ATP5F1C

1.41e-04403165930562941
Pubmed

Ovarian tumorB1-mediated heat shock transcription factor 1 deubiquitination is critical for glycolysis and development of endometriosis.

ABCF1 RPS2 PAK5 RPS16 BRSK1 FHL1 ATP5F1C

1.42e-04236165736339263
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF131 ZNF337 ZNF268 ZNF674 ZNF683 ZBTB26 ZNF285 ZNF236 ZNF416 ZNF708 ZNF594 ZNF600 SALL1 GZF1 ZNF530 ZNF517 ZNF253 ZNF814 ZNF552 ZNF81 ZNF615 ZNF614 ZNF574

2.50e-107181192328
GeneFamilyATP binding cassette subfamily A

ABCA10 ABCA8 ABCA5

9.60e-05141193805
GeneFamilyDyneins, axonemal

DNAH10 DNAH14 DNAH6

1.77e-04171193536
GeneFamilyRAB like GTPases

RABL2B RABL2A

4.24e-0451192394
GeneFamilyWD repeat domain containing

FBXW10B FBXW10 NBEA WDR5 PAAF1 SCAP WDR1

1.75e-032621197362
GeneFamilyWD repeat domain containing|F-box and WD repeat domain containing

FBXW10B FBXW10

2.27e-03111192559
GeneFamilyHelix-turn-helix CENPB type domain containing

TIGD2 JRKL

3.20e-03131192533
GeneFamilyCaspases|Caspase recruitment domain containing

CASP5 CASP6

3.20e-03131192468
GeneFamilyOlfactory receptors, family 52

OR52L1 OR52E8 OR52E6

4.11e-03491193165
GeneFamilyX-linked mental retardation|Angiotensin receptors

ZNF674 DLG3 ZNF81

5.13e-03531193103
ToppCellCV-Mild-6|Mild / Virus stimulation, Condition and Cluster

ZNF131 DNAH10 ZNF674 ZNF594 IGF2R STARD9 DTX2 CTNND1

3.05e-071751658c4d530dbb37942427c9cd0a1533faeb6a3a45381
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK3 RGS7BP DNAH10 WNT9B SEMA3A MET TLL1 DNAH6

3.05e-071751658f6e1d7297a4dbb38e1ab4f738d91f0e62abaee69
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

WNT9B ACSF2 CUBN DSCAML1 NRXN1 AFM KCNJ15 USH2A

3.94e-071811658c80ffa2ded5975a88e9a1a7d333196f95237bf0a
ToppCellLA-11._Adipocyte|LA / Chamber and Cluster_Paper

GPD1 MYCBP2 ACSF2 RETSAT F3 SEMA3A NWD2 ARHGAP20

4.28e-0718316583f9011976782fa8aa95cdd6f00f07a91094d411b
ToppCellFetal_29-31_weeks-Epithelial|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ANK3 F3 DNAH14 MET ANOS1 KCNJ15 NAV2 FGFR2

6.40e-071931658a0ca3231992f14abcf1a6129573bace320e89d2a
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_5|390C / Donor, Lineage, Cell class and subclass (all cells)

BDP1 HUS1B ADAM23 ZNF268 ZNF683 ZNF594 ZNF81

1.85e-061551657afdd0aba0f3788c2fb916ffb453c5dd7cde2304c
ToppCellChildren_(3_yrs)-Epithelial-basal_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

GCM2 ANK3 MET MELTF ANOS1 NRXN1 FGFR2

2.02e-0615716576ee2692f705bdd93ba523dffaf2f0cd921b47e28
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 PAK5 DSCAML1 SEMA3A TLL1 USH2A HYDIN

2.29e-061601657c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 PAK5 DSCAML1 SEMA3A TLL1 USH2A HYDIN

2.29e-06160165725c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellLV-11._Adipocyte|World / Chamber and Cluster_Paper

GPD1 ACSF2 RETSAT F3 SEMA3A NWD2 ARHGAP20

2.92e-0616616577e5852891714465c6228c9f955fd511ec79d0e02
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c07-TYROBP|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZNF337 ADCY1 ABCA8 ARL4C NRXN1 STARD9 MYBL1

3.04e-061671657ded4d6cccd3660662f12cf5a512de31d26325f1b
ToppCellCV-Mild-6|CV / Virus stimulation, Condition and Cluster

ZNF131 DNAH10 ZNF674 ARL4C ZNF594 STARD9 CTNND1

3.04e-061671657cf2ed0b6d17a16f9a2318879ce8856d5983ad3cf
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELF6 DNAH10 POLR2A CUBN USH2A DNAH6 HYDIN

3.29e-06169165712bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar-Macro_c6-VCAN|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ABCA8 TBC1D24 MET ZNF708 KIF9 RIOK2 ARHGAP45

3.42e-0617016570f215911b5880eeffeb43230f7eeaf55b612eaf2
ToppCell343B-Endothelial_cells-Endothelial-D|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CADM3 HSPG2 ADAM23 RPS2 RPS16 ZNF285 MET

3.42e-06170165752fdf93c2803fecb2a640ef4e0b257786f3d4cb1
ToppCell343B-Endothelial_cells-Endothelial-D-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CADM3 HSPG2 ADAM23 RPS2 RPS16 ZNF285 MET

3.42e-061701657263e98aa1c49493cc262b2608c6582930841cb10
ToppCellLV-11._Adipocyte|LV / Chamber and Cluster_Paper

GPD1 ACSF2 RETSAT F3 SEMA3A NWD2 ARHGAP20

3.84e-061731657c2d3fcb3de71015d03d14c63450853d2b03ffa71
ToppCellTCGA-Breast-Solid_Tissue_Normal|TCGA-Breast / Sample_Type by Project: Shred V9

GPD1 PAK5 ABCA10 ABCA8 STARD9 FHL1 ARHGAP20

3.98e-061741657e2f240d60bffbe8e6d60f0bb405b231bd3c96875
ToppCellTCGA-Breast-Solid_Tissue_Normal-Breast_normal_tissue-Breast_normal_tissue|TCGA-Breast / Sample_Type by Project: Shred V9

GPD1 PAK5 ABCA10 ABCA8 STARD9 FHL1 ARHGAP20

3.98e-0617416570f3ec0d0d4344e10c9b48adc9174123f6402dc51
ToppCellnormal_Lymph_Node-Myeloid_cells-pDCs|Myeloid_cells / Location, Cell class and cell subclass

FAM185A DNAH10 ANKHD1 MELTF IPO9 ABCA5 PRMT9

3.98e-0617416572274648b80dd74f3c948a779bba3391095964c34
ToppCellTCGA-Breast-Solid_Tissue_Normal-Breast_normal_tissue|TCGA-Breast / Sample_Type by Project: Shred V9

GPD1 PAK5 ABCA10 ABCA8 STARD9 FHL1 ARHGAP20

3.98e-0617416571aadbf2642b6d1320ceabd92e6ff59e11f16c315
ToppCell3'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-ILC2|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAM23 ZNF683 ARL4C PRMT9 ARHGAP45 ZNF614 MYBL1

4.63e-0617816575101a45595cd8d702f911afadf1eb0ee10bdcefc
ToppCellRV-11._Adipocyte|RV / Chamber and Cluster_Paper

GPD1 MYCBP2 ACSF2 RETSAT SEMA3A NWD2 ARHGAP20

4.63e-061781657278bbea5cf8f0589f71675c7a3d00679391b5253
ToppCellLA-11._Adipocyte|World / Chamber and Cluster_Paper

GPD1 ACSF2 RETSAT F3 SEMA3A NWD2 ARHGAP20

5.55e-061831657b177be283e1553fb1f69a346f1ba79ad00297fa2
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OTOA DNAH10 DSCAML1 MELTF NRXN1 USH2A HYDIN

5.75e-0618416572cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OTOA DNAH10 DSCAML1 MELTF NRXN1 USH2A HYDIN

5.75e-061841657ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OTOA DNAH10 DSCAML1 MELTF NRXN1 USH2A HYDIN

5.75e-0618416572b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellRA-11._Adipocyte|World / Chamber and Cluster_Paper

GPD1 MYCBP2 ACSF2 RETSAT F3 NWD2 ARHGAP20

6.62e-0618816574dac9d636e5cad4cda540b93d4bfed6b5732c880
ToppCelldroplet-Heart-HEART-1m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CADM3 ANK3 ADAM23 COL27A1 BRSK2 F3 NRXN1

6.62e-061881657921a2c9212a0f2a00fd72c594d80924f27e8b9b7
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CFAP47 ANK3 RIPK4 MET ANOS1 TLL1 FGFR2

6.86e-0618916577659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SIM1 DSCAML1 MAP3K1 MET MELTF SALL1 KCNJ15

7.10e-0619016571cf023e3c6924d6a06f353d4b62444b6f2fee8a7
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MFHAS1 DNAH14 MAP3K1 MET NAV2 WNT10A HYDIN

7.10e-0619016573fc9e18c7441c0ae8cda65753cc42d0520f4e116
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ANK3 F3 DNAH14 MET KCNJ15 NAV2 FGFR2

7.34e-061911657ca5669bd6f4a17471acae3eb229f845cc2e08efa
ToppCellEpithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|World / Lineage, Cell type, age group and donor

ANK3 F3 DNAH14 MET KCNJ15 NAV2 FGFR2

7.34e-061911657d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCellCOPD-Epithelial|COPD / Disease state, Lineage and Cell class

ANK3 F3 MET NAV2 FGFR2 DNAH6 HYDIN

7.60e-0619216570644fad5df18f0021f6f49cca996d8cf47f972ff
ToppCellLPS_only-Endothelial-Endothelial-Vein|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CADM3 HSPG2 VWF RGS7BP WNT9B TLL1 IL4I1

7.60e-06192165752acaecd3703166f5ce3b328aff7c82bd142fee4
ToppCellLPS-antiTNF-Endothelial-Endothelial-Vein|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CADM3 HSPG2 VWF RGS7BP WNT9B TLL1 IL4I1

7.60e-06192165781baf1c4063469bb0c03a8602b40e387ba7b0dfb
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ANK3 RGS7BP F3 DNAH14 MET KCNJ15 FGFR2

7.60e-061921657fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Vein|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CADM3 HSPG2 VWF RGS7BP WNT9B TLL1 IL4I1

7.86e-0619316577261c1ce30c796b61c6ec58e64a051baa24732ff
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ANK3 ACSF2 CUBN DNAH14 MET KCNJ15 PCCA

8.13e-0619416577002937e8903e037332a215d00fbc7c7843b33f2
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ANK3 MFHAS1 SIM1 DNAH14 MET FGFR2 PCCA

8.13e-0619416575eaaa81f4b2535f983c424aaef00077089526a5c
ToppCellIPF-Multiplet-Multiplet|IPF / Disease state, Lineage and Cell class

CFAP47 ANK3 DNAH10 NBEA NAV2 DNAH6 HYDIN

8.41e-061951657fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCellIPF-Multiplet|IPF / Disease state, Lineage and Cell class

CFAP47 ANK3 DNAH10 NBEA NAV2 DNAH6 HYDIN

8.41e-061951657eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCellCOPD-Multiplet-Multiplet|COPD / Disease state, Lineage and Cell class

CFAP47 ANK3 F3 MET NAV2 DNAH6 HYDIN

8.69e-061961657af4cdc61830685a888a1209826c23bcf54a43084
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-lymphocytic-T_lymphocytic-CD4-positive,_alpha-beta_memory_T_cell|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ANK3 ADAM23 MFHAS1 RPS2 RPS16 ARL4C FHL1

8.69e-061961657b10810c6a2ad3d3b968bfef46a68a38e0ce31331
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD8_EM-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CFAP47 BDP1 FAM185A ZNF674 ZBTB26 ANOS1 ZNF615

8.69e-0619616577e98380d815fbf6254289ace2af37aac6fef51e8
ToppCellCOPD-Multiplet|COPD / Disease state, Lineage and Cell class

CFAP47 ANK3 F3 MET NAV2 DNAH6 HYDIN

8.69e-0619616576d02d494196e3f857d53eea46d9419690d43beca
ToppCellNS-moderate-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CFAP47 DNAH10 KIF9 RABL2B RABL2A DNAH6 HYDIN

8.98e-06197165771fea4aa6ce96c7693fa94792d08770622873850
ToppCellFetal_29-31_weeks-Epithelial-club_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ANK3 XDH NBEA MET ANOS1 TLL1 NAV2

9.28e-0619816575fc25b008a4d8d6bec83923a16f64dd9e1ff1f2d
ToppCellIPF-Endothelial-VE_Peribronchial|Endothelial / Disease state, Lineage and Cell class

HSPG2 VWF MFHAS1 RPS2 MET NAV2 UCK2

9.28e-061981657b8bd1ba268480f54451648e01631b615a3401144
ToppCellNeuronal|World / cells hierarchy compared to all cells using T-Statistic

BDP1 ANK3 MYCBP2 ADAM23 PAK5 NBEA ABCA5

9.91e-06200165748d801219bc771d6c7e151dc88ca4c179988de85
ToppCellBiopsy_IPF-Epithelial-Ciliated|Biopsy_IPF / Sample group, Lineage and Cell type

CFAP47 DNAH10 KIF9 RABL2B RABL2A DNAH6 HYDIN

9.91e-062001657bb8c99156e547a8eb6599b6b6bc3c66bf77af7f8
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Upper_Layer_Occipital|World / Primary Cells by Cluster

BDP1 ANK3 RPS2 PAK5 NBEA ADCY1 DYNC1H1

9.91e-0620016576bbe8e1f3e91678f1bfb14945365c1578a59a604
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Upper_Layer_Occipital-19|World / Primary Cells by Cluster

BDP1 ANK3 RPS2 PAK5 NBEA ADCY1 DYNC1H1

9.91e-062001657c831d9e0a7178e3634da45548f91fa9e8dc6557c
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c11-GNLY|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

OTOA WNT9B XDH EDC4 IPO9 TIGD2

1.57e-0514316568f897278f9ccc82ae35e4f30c5f930b2a3eb509d
ToppCellP28-Epithelial-epithelial_progenitor_cell-epi_progenitor|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

GPD1 CFAP47 OTOA MET FGFR2 BRSK1

2.47e-051551656be575a0096415705dba425002247289ff8f89474
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

NBEA MET TLL1 ZNF552 DTX2 FGFR2

3.06e-0516116562d63b279d9a5132e1c09b03930bf9039036d24a2
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DNAH10 SIM1 NWD2 ABCA5 USH2A HYDIN

3.17e-051621656bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Ciliated_2|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

DNHD1 DNAH10 TRIM59 TYW1B DNAH6 HYDIN

3.51e-051651656731147b4337fd0de4383dc8170b4f9ccd98caec6
ToppCellPCW_07-8.5-Epithelial-Epithelial_ciliated-epi_ciliated_(14)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CFAP47 MET ANOS1 TLL1 DNAH6 HYDIN

3.51e-0516516560c714e852f912b5749de4cb0895406673979b2e6
ToppCellPCW_07-8.5-Epithelial-Epithelial_ciliated|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CFAP47 MET ANOS1 TLL1 DNAH6 HYDIN

3.51e-05165165682530f96aaefe28a13bad0474bbad043f127a86c
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

HSPG2 POLH MET GZF1 ZNF615 FGFR2

3.63e-05166165689e2b8453180983533faccb4275867861876d7ee
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RRM1 MELK ADCY1 ESCO2 ZNF530 MYBL1

3.75e-051671656108ae6221c6edc63c0ec42c42471b3a15a594043
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_5|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

HUS1B ADAM23 ZNF268 ZNF594 KCNJ15 ZNF81

3.88e-051681656d7d19c93d1c3dd994e18e28d5f36ae7773ff5d7f
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_5|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

HUS1B ADAM23 ZNF268 ZNF594 KCNJ15 ZNF81

4.01e-051691656d2def7229fe9d6b0c70cfed349ede491c8c137a0
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Basal_1|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

NBEA RIPK4 ACSF2 TRIM59 ZNF517 DNAH6

4.15e-051701656aabe993c9f337b1caaeb0e64626a3920579c41b7
ToppCellE18.5-samps-Epithelial-Alveolar_epithelial-AT2|E18.5-samps / Age Group, Lineage, Cell class and subclass

GPD1 ANK3 MET KCNJ15 NIPAL1 FGFR2

4.57e-051731656f6e36ea98a9c669ff393d141455aaecef083f738
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

AHCYL1 ANK3 GCGR SIM1 ABCA10 ABCA5

4.57e-0517316560c74bdb40e635d906fd180412c23bf7fed61621e
ToppCellTCGA-Breast-Solid_Tissue_Normal-Breast_normal_tissue-Breast_normal_tissue-3|TCGA-Breast / Sample_Type by Project: Shred V9

GPD1 ABCA10 ABCA8 STARD9 FHL1 ARHGAP20

4.72e-0517416567f8f5fafae08676d2b90cab9802c3c9320f1370e
ToppCell343B-Lymphocytic-NK_cells-NK_cell_D3|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

ZNF683 NBEA F3 ZNF416 ZNF517 DNAH6

5.03e-051761656bd5c85b3a4fb88ffe156599f6d224aa7664a513a
ToppCellfacs-Skin-Anagen-24m-Epithelial-actively_dividing_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM186B MELK DSCAML1 ESCO2 NIPAL1 MYBL1

5.19e-0517716568a0f0fbb06cdacb99a3fdba0da3e0494b891db4f
ToppCellRV-11._Adipocyte|World / Chamber and Cluster_Paper

GPD1 ACSF2 RETSAT SEMA3A NWD2 ARHGAP20

5.19e-051771656f0edf04930692418953e4f00a917257804ec0ffd
ToppCellfacs-Skin-Anagen-24m-Epithelial-keratinocyte_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM186B MELK DSCAML1 ESCO2 NIPAL1 MYBL1

5.19e-051771656e9d7682517fb30fd2ad535d59779d718a7024c13
ToppCellChildren_(3_yrs)-Epithelial-basal_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

ANK3 RGS7BP MET ANOS1 NRXN1 FGFR2

5.36e-051781656fba2e38c05cbf031e0c6d47b1602575fea734a57
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Children_(3_yrs) / Lineage, Cell type, age group and donor

ANK3 POLH MET KCNJ15 NAV2 FGFR2

5.52e-051791656cb38b54261a7af5ee3347e64c8aa880a77ed0763
ToppCellCOVID-19-kidney-PCT-S2|COVID-19 / Disease (COVID-19 only), tissue and cell type

COL27A1 CUBN DSCAML1 SLC5A2 MET KCNJ15

5.70e-051801656358923e4228035a3e90e2957392089219e90dcd7
ToppCellRA-11._Adipocyte|RA / Chamber and Cluster_Paper

GPD1 ACSF2 RETSAT F3 NWD2 ARHGAP20

5.70e-051801656d48a3d27357f7d184132a6805950f93080146b59
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWF RGS7BP WNT9B MAP3K1 SEMA3A TLL1

5.88e-051811656cef034030e6b029a49ae56be37ea1fac1a5c350e
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HSPG2 RIPK4 F3 DSCAML1 ANOS1 NAV2

5.88e-051811656b45b11428d13950369347e051d4d517efb2bd4fd
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CFAP47 DNAH10 RABL2B RABL2A DNAH6 HYDIN

5.88e-051811656dfce05bd472f67e6e2bb60ebd6fd34f0a9aeeca6
ToppCellControl-Epithelial_cells-Airway_club|Control / group, cell type (main and fine annotations)

ANK3 MFHAS1 MET KCNJ15 NAV2 FGFR2

5.88e-051811656c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

XDH NBEA MET TLL1 DTX2 FGFR2

6.06e-051821656215c303df42f13597b2c7a95cb157c6bc7aca9a1
ToppCellCOVID-19-kidney-PCT-S1|COVID-19 / Disease (COVID-19 only), tissue and cell type

COL27A1 CUBN DSCAML1 SALL1 KCNJ15 HYDIN

6.24e-0518316566878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL27A1 ACSF2 CUBN SLC5A2 AFM KCNJ15

6.24e-05183165684b64cf728629c3af9a8d2ed15b93adf562c54b8
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Endothelial-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RGS7BP DNAH10 ACSF2 KIF9 PRMT9 DNAH6

6.24e-051831656919c9861073d12fd12aecd7469b1478b13838c43
ToppCellCOVID-19_Severe-gd_T|COVID-19_Severe / Disease condition and Cell class

DNAH10 ZNF683 ARL4C ZNF600 IGF2R MYBL1

6.44e-051841656791f1bcb954aadc63d4117c400537d036f68734d
ToppCelldroplet-Liver-LIVER_HEP-30m-Mesenchymal|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP47 CADM3 HUS1B ANK3 NRXN1 FHL1

6.63e-051851656f814ec9d4ade717a0109398e9768d0d66f09317b
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CADM3 RGS7BP ADCY1 NWD2 TLL1 WNT10A

6.63e-051851656cdd75abdaa1ecedfd2e636203b83a6ac1782f0c3
ToppCelldroplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP47 CADM3 HUS1B ANK3 NRXN1 FHL1

6.63e-05185165640e958511790e84321da5ccf735f9974c06a0263
ToppCelldroplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP47 CADM3 HUS1B ANK3 NRXN1 FHL1

6.63e-0518516565f2eeba80aff145e85cfd81e2890a155406badb9
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HSPG2 RIPK4 F3 DSCAML1 ANOS1 NAV2

6.83e-0518616563aebe163799109ffc67e4e10ee47c2dd0886a92c
ToppCellControl-Endothelial-Endothelial-Vein|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CADM3 HSPG2 VWF RGS7BP WNT9B TLL1

6.83e-05186165692092f11ecce22c14f244e42c499af0822977e6f
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ANK3 F3 DNAH14 MET KCNJ15 NAV2

6.83e-051861656acfa68a2afb7d2b51c9b469a1965fe5cc5d5e64e
ToppCellPND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ANK3 RETSAT MET KCNJ15 NIPAL1 FGFR2

7.04e-0518716566ab51e17a7782c2ae6394cad813dc3a2cde70c89
ToppCelldroplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPD1 RIPK4 TRIM59 MET WNT10A UCK2

7.04e-05187165622fd1959879705a8c1128faa9de66696c4e0b7e3
ToppCellCOVID-19-Endothelial_cells-Pulmonary_venous_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

HSPG2 VWF ADAM23 WNT9B MET TLL1

7.04e-0518716562d20193a6cacdfa4877457c97b0077408942186c
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c07-AHNAK|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

ANK3 ADAM23 ARL4C FHL1 IL4I1 MYBL1

7.04e-051871656e1d6c1194476cf26969e405b0951796fed519f44
ToppCelldroplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Neuronal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPD1 RIPK4 TRIM59 MET WNT10A UCK2

7.04e-0518716565fae538de481367cf6d9a2d52190d77b99f6922c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MFHAS1 SIM1 ABCA10 MET ABCA5 PCCA

7.04e-05187165677886f99c229610abd28c4c370d2c7d1536c9782
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SIM1 DSCAML1 MAP3K1 MET MELTF KCNJ15

7.04e-051871656c41a2c81dd2ceef303f39f699032aa7d6ea67cf0
Diseasevon Willebrand's disease (is_implicated_in)

VWF F3

2.78e-0521562DOID:12531 (is_implicated_in)
Diseasepropionic acidemia (is_implicated_in)

PCCA PCCB

2.78e-0521562DOID:14701 (is_implicated_in)
DiseasePropionicaciduria

PCCA PCCB

2.78e-0521562C2717876
Diseasenonsyndromic deafness (is_implicated_in)

TBC1D24 USH2A

2.78e-0521562DOID:0050563 (is_implicated_in)
DiseasePROPIONIC ACIDEMIA

PCCA PCCB

2.78e-0521562606054
DiseasePropionic acidemia

PCCA PCCB

2.78e-0521562cv:C0268579
Diseaseserine/threonine-protein kinase BRSK2 measurement

BRSK2 BRSK1

8.30e-0531562EFO_0803063
DiseasePropionic acidemia

PCCA PCCB

8.30e-0531562C0268579
DiseaseParoxysmal atrial fibrillation

HSPG2 VWF DNAH10 RPS2 NAV2 WDR1

1.88e-041561566C0235480
Diseasefamilial atrial fibrillation

HSPG2 VWF DNAH10 RPS2 NAV2 WDR1

1.88e-041561566C3468561
DiseasePersistent atrial fibrillation

HSPG2 VWF DNAH10 RPS2 NAV2 WDR1

1.88e-041561566C2585653
DiseaseAtrial Fibrillation

HSPG2 VWF DNAH10 RPS2 NAV2 WDR1

2.15e-041601566C0004238
Diseaseinsulin-like growth factor-binding protein 7 measurement

AFM UBA6

4.11e-0461562EFO_0008161
Diseaseparenchymal hematoma, response to recombinant tissue-plasminogen activator

DSCAML1 SEMA3A

4.11e-0461562EFO_0020101, EFO_0600080
DiseaseMental Retardation, X-Linked

ZNF674 DLG3 ZNF81

4.79e-04291563C1136249
Diseasemultiple myeloma (is_marker_for)

XDH FASLG IGF2R

9.11e-04361563DOID:9538 (is_marker_for)
DiseaseNonsyndromic Deafness

OTOA BDP1 TBC1D24 MET

9.12e-04811564C3711374
Diseasevery low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio

DNAH10 MFHAS1 ABCA8 IGF2R TYW1B TASOR PCCB

9.42e-042911567EFO_0008317, EFO_0020946
DiseaseHEPATOCELLULAR CARCINOMA

MET IGF2R

9.76e-0491562114550
DiseaseHepatocellular carcinoma

MET IGF2R

9.76e-0491562cv:C2239176
Diseasecorpus callosum anterior volume measurement

SEMA3A NAV2 PCCA

1.15e-03391563EFO_0010295
Diseasealopecia areata (is_marker_for)

KDM4B HDAC1

1.22e-03101562DOID:986 (is_marker_for)
Diseaseautism spectrum disorder (implicated_via_orthology)

NBEA DSCAML1 MET NRXN1 CTNND1

1.31e-031521565DOID:0060041 (implicated_via_orthology)
Diseaseamino acid metabolic disorder (is_implicated_in)

PCCA PCCB

1.48e-03111562DOID:9252 (is_implicated_in)
DiseaseMalignant neoplasm of breast

VWF ACO2 POLH XDH SIM1 CUBN TRAPPC8 F3 MAP3K1 SEMA3A TLL1 KCNJ15 FGFR2 HERC2

1.74e-03107415614C0006142
Diseasediabetic angiopathy (is_marker_for)

FASLG F3

1.77e-03121562DOID:11713 (is_marker_for)
Diseasegraft-versus-host disease (is_marker_for)

FASLG F3

1.77e-03121562DOID:0081267 (is_marker_for)
Diseaseretinal vasculature measurement

CELF6 HSPG2 RGS7BP CTC1 ACO2 PAAF1 DSCAML1 FGFR2 HERC2

1.79e-035171569EFO_0010554
DiseaseMental Retardation, X-Linked Nonsyndromic

DLG3 ZNF81

2.08e-03131562C3501611
DiseaseCardiomyopathy, Familial Idiopathic

FASLG PCCA PCCB

2.37e-03501563C1449563
Diseasevery low density lipoprotein cholesterol measurement

DNAH10 ABCA10 DSCAML1 IGF2R TYW1B PCCB

2.67e-032601566EFO_0008317
DiseaseProteinuria

VWF CUBN

2.79e-03151562HP_0000093
Diseasevery low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio

DNAH10 MFHAS1 ABCA8 IGF2R TYW1B PCCB

2.88e-032641566EFO_0008317, EFO_0020944
Diseasetriglyceride measurement, intermediate density lipoprotein measurement

DNAH10 IGF2R TYW1B PCCB

2.90e-031111564EFO_0004530, EFO_0008595
Diseasepulse pressure measurement

MFHAS1 COL27A1 WNT9B NBEA FAM186B TRIM59 MET MELTF GCAT ANKDD1A ZNF638 CTNND1 WDR1 FHL1 HYDIN KDM4B

2.95e-03139215616EFO_0005763
Diseaseresponse to acetylsalicylate

KIF9 SCAP

3.17e-03161562GO_1903492
DiseaseBenign neoplasm of stomach

MET FGFR2

3.59e-03171562C0153943
DiseaseNeoplasm of uncertain or unknown behavior of stomach

MET FGFR2

3.59e-03171562C0496905
DiseaseMultiple congenital anomalies

NRXN1 FGFR2

3.59e-03171562C0000772
DiseaseCarcinoma in situ of stomach

MET FGFR2

3.59e-03171562C0154060
DiseaseLimb Deformities, Congenital

SALL1 FGFR2

3.59e-03171562C0206762
Diseaseatrial fibrillation

HSPG2 DNAH10 RPS2 POLR2A NAV2 WDR1 PCCA

3.70e-033711567EFO_0000275
Diseasediet measurement

ANK3 ADAM23 MFHAS1 ACO2 C15orf40 FAM186B DNAH14 ARL4C NWD2 TLL1 NIPAL1 PCCA PCCB

3.89e-03104915613EFO_0008111
DiseaseDisorder of organic acid metabolism

PCCA PCCB

4.02e-03181562cv:C1263739
Diseasepancreatic ductal carcinoma (is_marker_for)

FASLG MET HDAC1

4.17e-03611563DOID:3587 (is_marker_for)
Diseasecutaneous melanoma, hair color

MAP3K1 HERC2 ARHGAP20

4.36e-03621563EFO_0000389, EFO_0003924
Diseaseprion disease

MFHAS1 SEMA3A

4.48e-03191562EFO_0004720
Diseasecarotid artery disease (is_marker_for)

HSPG2 VWF

4.48e-03191562DOID:3407 (is_marker_for)
Diseaseneuroimaging measurement

ANK3 PAK5 BRSK2 SLC25A16 F3 MAP3K1 SEMA3A YOD1 NAV2 FGFR2 WDR1 PCCA KDM4B

4.56e-03106915613EFO_0004346
Diseasetriglycerides:total lipids ratio, high density lipoprotein cholesterol measurement

DNAH10 ABCA8 IGF2R TYW1B PCCB

4.87e-032061565EFO_0004612, EFO_0020947
Diseaseurinary microalbumin measurement

CUBN SLC25A16

4.96e-03201562EFO_0010967
Diseasecoagulation factor measurement

VWF F3

4.96e-03201562EFO_0004634
Diseasecholesterol in large VLDL measurement

DNAH10 IGF2R PCCB

4.98e-03651563EFO_0021902
Diseasecholesterol in very large VLDL measurement

DNAH10 IGF2R PCCB

4.98e-03651563EFO_0022230

Protein segments in the cluster

PeptideGeneStartEntry
LRCIGTVQHLKSKFG

ABCA5

1511

Q8WWZ7
SAAVAKQALAHGLKC

ACO2

396

Q99798
HTIQICKLSGGQKAR

ABCF1

736

Q8NE71
SKLACVHGIKGTSIS

BDP1

2166

A6H8Y1
KDSKVALSTCNGLHG

ADAM23

206

O75077
QKAVCLGSKSVLDIG

PRMT9

171

Q6P2P2
KIKLSNGTAKGISCH

ARL4C

51

P56559
QVLLGVLVASSHKGC

CTC1

606

Q2NKJ3
GTLRCIGSIQHLKNK

ABCA10

1416

Q8WWZ4
KHVCGALLKFGTKVV

AFM

221

P43652
QCGKGLSSKTALRLH

GZF1

411

Q9H116
LVKTLSGHEGAVKCL

FBXW10

566

Q5XX13
KAGCQLLTVHGRTKE

DUS1L

166

Q6P1R4
VQGCTKKHLNSKTVG

ACSF2

61

Q96CM8
GQIALIKHGSRLKNC

CDADC1

111

Q9BWV3
GGLQIKFHCSKQLSL

FAM186B

451

Q8IYM0
TKGGLLLLSCHDVQA

DNHD1

766

Q96M86
SLEKFHSLVLKLCGG

ABCD4

581

O14678
ATVLGHTGQVCLFLK

ACAP2

681

Q15057
VAGGTVVLKCQVKDH

CADM3

41

Q8N126
TVLKDRLTGLHKGCA

CELF6

76

Q96J87
LVLKTHVNLLCGGVA

SLC25A16

236

P16260
SCLLSEVEIKGTKHG

NWD2

1041

Q9ULI1
KSICLLGSLQFHRKG

RGS7BP

141

Q6MZT1
GVGKSCLLHQFTEKK

RAB14

21

P61106
GITGCVKNLVLHSAR

HSPG2

4351

P98160
IKQGFIVVKGHSTCL

EDC4

286

Q6P2E9
CKAKDGTHVLQGLSS

YOD1

51

Q5VVQ6
GFAKVKLACHILTGE

MELK

21

Q14680
NVKIICLGDSAVGKS

RABL2A

21

Q9UBK7
NVKIICLGDSAVGKS

RABL2B

21

Q9UNT1
LVKTLSGHEGAVKCL

FBXW10B

566

O95170
GIVCIATEKHTGKQV

PAK5

461

Q9P286
LSAGQLVKGVTCSHI

OTOA

576

Q7RTW8
IGKHKNIINLLGACT

FGFR2

541

P21802
CLGEAGHVLSKVLAK

ANOS1

536

P23352
ETLAIQCGHKKLQGR

ARHGAP45

741

Q92619
GHKAAGKTLLRHCLT

MFHAS1

416

Q9Y4C4
LGCFNLTIKGHAKCV

HDAC1

271

Q13547
SKAIGSLAVGHLTKC

DTX2

431

Q86UW9
KVAVNSGGKHCLALS

HERC2

4041

O95714
LHVQTKGGKVICLGT

FAM185A

191

Q8N0U4
GLVKLGVHCVTCQKV

BRSK2

31

Q8IWQ3
IQTLTGLFKGDKCHS

CASP6

136

P55212
LKALNTCGSHIGVIL

OR52E6

236

Q96RD3
AILGGLSKLHCTRNA

GCGR

161

P47871
SHCAVITKQNGKLCL

KCNJ15

181

Q99712
HGKIGCLLSILGSTV

NIPA2

111

Q8N8Q9
ITCLKHKSGGHAVQL

KDM4B

901

O94953
NATGLHKLKLCVVGK

JRKL

216

Q9Y4A0
CGTQSIHKNLEAKIA

GCAT

106

O75600
KLTHALKDSLGGNCN

KIF9

296

Q9HAQ2
KLVHAKEGFQGCLAS

NRXN1

1041

Q9ULB1
TKGICKALSTCGSHL

OR1J1

231

Q8NGS3
AGKTGTVKSVHCQAG

PCCA

701

P05165
ASCVVTFKGHKGGIL

PAAF1

166

Q9BRP4
NGVIFGIICLDSKLH

OR2A2

41

Q6IF42
GSLSGAHAQKICKIM

PCCB

131

P05166
GKVCGNGTISHIKSI

CUBN

776

O60494
HCVKCNKAITSGGIT

FHL1

161

Q13642
GKVHITKTTLACLNG

ADCY1

436

Q08828
TGKQSLTRLAAHICG

DNAH6

2451

Q9C0G6
VCHAIIGAQKGKSLV

HYDIN

1021

Q4G0P3
SHGILEGICGTAHKK

CASP5

266

P51878
NTTIAIKGHAKELNC

DSCAML1

796

Q8TD84
VSSGKKTGVLQGHCV

ANK3

3826

Q12955
HGGQTCLKPITASKV

COL27A1

1726

Q8IZC6
GKHCILDVSGNAIKR

DLG3

716

Q92796
GLVKLGVHCITGQKV

BRSK1

46

Q8TDC3
ACISGLHVDVGNLKA

DNAH14

841

Q0VDD8
IIDAGQKHFGATVCK

ESCO2

376

Q56NI9
ICDQLKGHLKANATG

GPD1

101

P21695
KITGKGCLELFIHVS

HUS1B

6

Q8NHY5
GKVSSVALCKLLQHG

IPO9

856

Q96P70
AASGGAKELKNIHVC

DYNC1H1

4496

Q14204
GLCGAIHSSIAKQMK

ATP5F1C

101

P36542
VKKSALCGEQVHILG

ELP5

46

Q8TE02
EKGGKVSIVSHSLGC

DDHD1

526

Q8NEL9
GCKQAIGKFESLVHQ

DNAH10

761

Q8IVF4
CAHQKPITALKAAAG

SCAP

1076

Q12770
ICGNRFSTKGNLKVH

SALL1

481

Q9NSC2
FQGNALKLKCVAHLG

CFAP47

936

Q6ZTR5
KKEVHLGACGALKNI

CTNND1

421

O60716
SLIAKHLKGRIGKQC

MYBL1

111

P10243
LNIHGKIGCILSILG

NIPAL1

166

Q6NVV3
GLVAAKVLSDAGHKV

IL4I1

71

Q96RQ9
KALNTCGSHIGVILA

OR52E8

241

Q6IFG1
LGKLIFCQATIIGHA

OR52L1

181

Q8NGH7
LHKSLVCTALRGKLG

FIBP

256

O43427
VHLEKTGKGLCATKL

MAP3K1

906

Q13233
NSRHISIGGKTCTLK

MET

686

P08581
DCGHGKKIKTNITLV

IGF2R

571

P11717
KKQHKTSCEAGLLHG

ARHGAP20

866

Q9P2F6
KRVLVLEQHTKAGGC

RETSAT

91

Q6NUM9
ACGVSVKKGHELVNI

RETSAT

331

Q6NUM9
KESLAGQGLCLLVSH

USH2A

4396

O75445
TAGEHNKACSLLGKL

DARS2

441

Q6PI48
IDTLKGVKSCHTGIN

MELTF

121

P08582
ISIGKNCDKFGIVVH

TLL1

226

O43897
KPLAGAKIVGCTHIT

AHCYL1

141

O43865
IVTSLKSKGKGFQHC

NBEA

301

Q8NFP9
NHNGHILKKSCLGVV

GCM2

71

O75603
KTSICNHLLRGSGIK

NEPRO

421

Q6NW34
HLFLIGCIGVSGKTK

NAV2

2036

Q8IVL1
AVAHCKRGNGLIKVN

RPS16

21

P62249
QLASINGAGKKHSLC

SIM1

591

P81133
AALQVCKTHSGILGK

MYCBP2

2196

O75592
CKTHSGILGKGLALS

MYCBP2

2201

O75592
KSIQCLTVHKNGGKS

WDR1

321

O75083
QCSAGISHNKVLAKL

POLH

211

Q9Y253
HSGKATHARIGQICK

SEMA3A

256

Q14563
LGTHKAAKGASCNSL

STARD9

996

Q9P2P6
HVKISDFGLAKCNGL

RIPK4

156

P57078
AVCGGLGRKKLTHLV

MRPS18C

6

Q9Y3D5
VQTICEKGLHVGQSK

TASOR

191

Q9UK61
LRCIGSIQHLKSKFG

ABCA8

1496

O94911
SKDGLTLLHCAAQKG

ANKDD1A

121

Q495B1
AGHLCTVQFLISKGA

ANKHD1

611

Q8IWZ3
GCVTIAIHAKPGSKQ

C15orf40

61

Q8WUR7
DIVGKIVGKHSSSCL

TBC1D24

76

Q9ULP9
KCGKGFTLKNSLITH

ZNF615

376

Q8N8J6
NATGLHKLNLCVVGK

TIGD2

216

Q4W5G0
GHSLEGCFQVIKLLS

UBA6

676

A0AVT1
QCGKGFSLKSQLIVH

ZNF268

476

Q14587
TVGNCLHKTAVLAGT

TMEM11

76

P17152
RILVGNKGCSHPSVK

VWF

906

P04275
CLAGKSLTHIKAGCI

SLC5A2

301

P31639
KQCALISKSAGGIGV

RRM1

236

P23921
CKKSLGTSAGSLVHI

POLR2A

641

P24928
TCGKKVGSAARLQAH

ZNF574

671

Q6ZN55
FAKDKVTCVGHIIGA

XDH

656

P47989
VHCKGKIQLTTELGF

RFPL3

201

O75679
SGKSSVCAKIVQLLG

UCK2

31

Q9BZX2
AISLHKCRKAGVGQS

F3

271

P13726
IASLKHGGCNKVLRE

RIOK2

41

Q9BVS4
LKKRGNHSTGLCLLV

FASLG

71

P48023
CGKAFGRKSNLTLHQ

ZNF517

401

Q6ZMY9
GLKAHLASCSKGAHL

ZNF512B

766

Q96KM6
HKGGHKGLNRCVTTT

ZNF708

121

P17019
HTGINLFKCIICGKA

ZNF253

166

O75346
GKSFSLKCGLIQHQL

ZNF416

416

Q9BWM5
GICGKLFNSKSHLLV

ZNF552

271

Q9H707
THTGLKSFKCLICNG

ZNF236

706

Q9UL36
CGKAFKGSSNLVLHQ

ZNF594

216

Q96JF6
ETKKGNTGIIHGACL

TRAPPC8

326

Q9Y2L5
ECGKSFGQKSVLIQH

ZNF530

411

Q6P9A1
LKCHLTACQTGVGAK

ZNF131

371

P52739
VVHAVSNACALGKLK

WNT10A

141

Q9GZT5
CGKGFTVKSNLIVHQ

ZNF614

376

Q8N883
LPCVLGKNVFTSGKH

TRIM4

366

Q9C037
HVGIKAVKSGLRTTC

WNT9B

196

O14905
CGKAFGEKSTLIVHQ

ZNF674

446

Q2M3X9
HVGLGVKCSKEVATA

RPS2

136

P15880
CGKIFGQNSALVIHK

ZNF600

251

Q6ZNG1
VLCKHKGITSGRAQL

TMEM254

81

Q8TBM7
LCLLGAKHIEAGVTQ

TRBV14

11

A0A5B0
VSSGKCLKTLKGHSN

WDR5

116

P61964
RSLLCIHQGVHTGKK

ZNF285

356

Q96NJ3
NLGGHSIRCKSKNLE

ZNF638

631

Q14966
LDKKLVCGHCLTIGQ

TRIM59

111

Q8IWR1
SNCLLIAHRKFKIGG

TYW1B

586

Q6NUM6
LLCGKTFTQKGNLHR

ZBTB26

301

Q9HCK0
ICGKSFGQLSNLKVH

ZNF683

326

Q8IZ20
ECGKSFSQKGNLVLH

ZNF814

496

B7Z6K7
CGKVLSLKHSLSQNV

ZNF81

251

P51508
ECGQGFIQKSTLVKH

ZNF337

436

Q9Y3M9
FVKHLSLGSVQLCGV

AGL

1036

P35573