Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC12A6 SLCO1B3 SLC25A30 SLC46A1 MFSD4B SLC22A7 SLCO1B7 SLC38A1 SLC22A8 SLC20A1 SLC20A2 SLC17A8 SLC12A7 SLC26A11 SLC16A7 SLC25A23 SLC16A8

2.13e-1229611917GO:0015291
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC12A6 SLCO1B3 COX15 SLC25A30 SLC46A1 MFSD4B SLC22A7 SLCO1B7 SLC38A1 SLC22A8 SLC20A1 SLC20A2 SLC17A8 SLC12A7 SLC26A11 SLC16A7 SLC25A23 SLC16A8

4.67e-1047711918GO:0022804
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLCO1B3 SLC46A1 GRIK3 GRIN1 SLC22A7 SLCO1B7 SLC38A1 SLC22A8 SLC17A8 SLC26A11 SLC16A7 SLC25A23 SLC33A1 SLC16A8

2.34e-0929311914GO:0008514
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLC12A6 NOX5 SLCO1B3 COX15 SLC25A30 SLC46A1 GRIK3 GRIN1 MFSD4B SLC22A7 SLC22A12 SLCO1B7 SLC38A1 PIEZO2 SLC22A8 SLC20A1 SLC20A2 KCNN3 SLC17A8 CACNA1H SLC12A7 SLC26A11 SLC16A7 SLC25A23 SLC33A1 SLC16A8

5.17e-09118011926GO:0022857
GeneOntologyMolecularFunctiontransporter activity

SLC12A6 NOX5 SLCO1B3 COX15 SLC25A30 SLC46A1 GRIK3 GRIN1 MFSD4B SLC22A7 SLC22A12 SLCO1B7 PITPNM1 SLC38A1 PIEZO2 SLC22A8 SLC20A1 SLC20A2 KCNN3 SLC17A8 CACNA1H SLC12A7 SLC26A11 SLC16A7 SLC25A23 SLC33A1 SLC16A8

7.25e-09128911927GO:0005215
GeneOntologyMolecularFunctionsymporter activity

SLC12A6 SLC46A1 MFSD4B SLC38A1 SLC20A1 SLC20A2 SLC17A8 SLC12A7 SLC16A7 SLC16A8

2.24e-0815011910GO:0015293
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

SLCO1B3 SLC46A1 GRIK3 GRIN1 SLC22A7 SLCO1B7 SLC38A1 SLC17A8 SLC16A7 SLC16A8

4.60e-0720711910GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

SLCO1B3 SLC46A1 GRIK3 GRIN1 SLC22A7 SLCO1B7 SLC38A1 SLC17A8 SLC16A7 SLC16A8

4.80e-0720811910GO:0005342
GeneOntologyMolecularFunctioninorganic anion transmembrane transporter activity

SLC12A6 SLC25A30 SLC22A8 SLC20A1 SLC20A2 SLC17A8 SLC12A7 SLC26A11 SLC25A23

8.66e-071711199GO:0015103
GeneOntologyMolecularFunctionprostaglandin transmembrane transporter activity

SLCO1B3 SLC22A7 SLCO1B7 SLC22A8

1.15e-06141194GO:0015132
GeneOntologyMolecularFunctionicosanoid transmembrane transporter activity

SLCO1B3 SLC22A7 SLCO1B7 SLC22A8

1.56e-06151194GO:0071714
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

SLC12A6 NOX5 COX15 SLC25A30 SLC46A1 GRIK3 GRIN1 SLC38A1 SLC22A8 SLC20A1 SLC20A2 KCNN3 SLC17A8 CACNA1H SLC12A7 SLC26A11 SLC25A23

2.57e-0675811917GO:0015318
GeneOntologyMolecularFunctionsolute:monoatomic cation symporter activity

SLC12A6 SLC46A1 SLC38A1 SLC20A1 SLC20A2 SLC17A8 SLC12A7

7.22e-061191197GO:0015294
GeneOntologyMolecularFunctionphosphate transmembrane transporter activity

SLC20A1 SLC20A2 SLC17A8 SLC25A23

1.16e-05241194GO:0005315
GeneOntologyMolecularFunctionsolute:inorganic anion antiporter activity

SLC25A30 SLC22A8 SLC26A11 SLC25A23

3.79e-05321194GO:0005452
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

SLC12A6 NOX5 COX15 SLC46A1 GRIK3 GRIN1 SLC38A1 PIEZO2 SLC20A1 SLC20A2 KCNN3 SLC17A8 CACNA1H SLC12A7

4.17e-0566411914GO:0008324
GeneOntologyMolecularFunctionsodium:phosphate symporter activity

SLC20A1 SLC20A2 SLC17A8

4.37e-05121193GO:0005436
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

SLC12A6 NOX5 COX15 SLC46A1 GRIK3 GRIN1 SLC38A1 PIEZO2 SLC20A1 SLC20A2 KCNN3 SLC17A8 CACNA1H SLC12A7 SLC26A11

7.49e-0579311915GO:0015075
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

SLC12A6 COX15 SLC46A1 SLC38A1 SLC20A1 SLC20A2 SLC17A8 SLC12A7 SLC26A11

8.10e-053011199GO:0022853
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

SLC12A6 NOX5 COX15 SLC46A1 GRIK3 GRIN1 SLC38A1 SLC20A1 SLC20A2 KCNN3 SLC17A8 CACNA1H SLC12A7

9.43e-0562711913GO:0022890
GeneOntologyMolecularFunctionprotein-L-isoaspartate (D-aspartate) O-methyltransferase activity

PCMTD1 PCMTD2

1.05e-0431192GO:0004719
GeneOntologyMolecularFunctionamide transmembrane transporter activity

SLCO1B3 SLC46A1 SLCO1B7 SLC33A1

1.13e-04421194GO:0042887
GeneOntologyMolecularFunctionsodium-independent organic anion transmembrane transporter activity

SLCO1B3 SLC22A7 SLCO1B7

1.58e-04181193GO:0015347
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH2 DNAH7 DNAH11

1.58e-04181193GO:0008569
GeneOntologyMolecularFunctionserine-type carboxypeptidase activity

CPD CPVL

3.48e-0451192GO:0004185
GeneOntologyMolecularFunctiontetrapyrrole binding

CYP26B1 TCN2 NOX5 COX15 CUBN CYP46A1

4.52e-041641196GO:0046906
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SLC12A6 GRIK3 GRIN1 SLC38A1 SLC20A1 SLC20A2 KCNN3 SLC17A8 CACNA1H SLC12A7

4.72e-0446511910GO:0046873
GeneOntologyMolecularFunctionlactate transmembrane transporter activity

SLC16A7 SLC16A8

5.20e-0461192GO:0015129
GeneOntologyMolecularFunctionglutamate receptor activity

GRIK3 GRIN1 GRM5

5.44e-04271193GO:0008066
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

GRIK3 SLC38A1 SLC20A1 SLC20A2 SLC17A8 CACNA1H

5.64e-041711196GO:0015081
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH2 DNAH7 DNAH11

6.06e-04281193GO:0051959
GeneOntologyMolecularFunctionprotein carboxyl O-methyltransferase activity

PCMTD1 PCMTD2

7.25e-0471192GO:0051998
GeneOntologyMolecularFunctionMutSalpha complex binding

TREX1 MLH1

7.25e-0471192GO:0032407
GeneOntologyMolecularFunctioncarboxyl-O-methyltransferase activity

PCMTD1 PCMTD2

7.25e-0471192GO:0010340
GeneOntologyMolecularFunctionorganic hydroxy compound transmembrane transporter activity

SLCO1B3 SLCO1B7 SLC16A7 SLC16A8

8.12e-04701194GO:1901618
GeneOntologyMolecularFunctionlipid transmembrane transporter activity

SLCO1B3 SLC22A7 SLCO1B7 SLC22A8

9.51e-04731194GO:0170055
GeneOntologyMolecularFunctionchannel activity

SLC12A6 NOX5 GRIK3 GRIN1 PIEZO2 KCNN3 SLC17A8 CACNA1H SLC12A7 SLC26A11

1.19e-0352511910GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

SLC12A6 NOX5 GRIK3 GRIN1 PIEZO2 KCNN3 SLC17A8 CACNA1H SLC12A7 SLC26A11

1.21e-0352611910GO:0022803
GeneOntologyMolecularFunctionG protein-coupled glutamate receptor activity

GRIK3 GRM5

1.23e-0391192GO:0098988
GeneOntologyMolecularFunctionpotassium:chloride symporter activity

SLC12A6 SLC12A7

1.23e-0391192GO:0015379
GeneOntologyMolecularFunctionadenylate cyclase inhibiting G protein-coupled glutamate receptor activity

GRIK3 GRM5

1.23e-0391192GO:0001640
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNAH2 DNAH7 DNAH11

1.38e-03371193GO:0045505
GeneOntologyMolecularFunctionsolute:sodium symporter activity

SLC38A1 SLC20A1 SLC20A2 SLC17A8

1.40e-03811194GO:0015370
GeneOntologyMolecularFunctioncobalamin binding

TCN2 CUBN

1.54e-03101192GO:0031419
GeneOntologyMolecularFunctioncalcium ion binding

PCDHGB2 NOX5 PCDHGA10 PCDHGA5 PCDHGA1 GRIN1 CUBN DNAH7 PITPNM1 FAT1 GCA SLC25A23

1.72e-0374911912GO:0005509
GeneOntologyMolecularFunctionmismatch repair complex binding

TREX1 MLH1

1.87e-03111192GO:0032404
GeneOntologyMolecularFunctionmonocarboxylic acid transmembrane transporter activity

SLCO1B3 SLCO1B7 SLC16A7 SLC16A8

2.07e-03901194GO:0008028
GeneOntologyMolecularFunctionserine-type exopeptidase activity

CPD CPVL

2.24e-03121192GO:0070008
GeneOntologyMolecularFunctionammonium channel activity

SLC12A6 SLC12A7

2.24e-03121192GO:0008519
GeneOntologyMolecularFunctionvitamin binding

TCN2 SLC46A1 CUBN AGXT MOCOS

2.80e-031611195GO:0019842
GeneOntologyMolecularFunctionarylsulfatase activity

ARSH ARSL

3.06e-03141192GO:0004065
GeneOntologyMolecularFunctionamino acid transmembrane transporter activity

GRIK3 GRIN1 SLC38A1 SLC17A8

3.61e-031051194GO:0015171
GeneOntologyMolecularFunctionoligopeptide transmembrane transporter activity

SLCO1B3 SLCO1B7

4.00e-03161192GO:0035673
GeneOntologyMolecularFunctionsulfuric ester hydrolase activity

ARSH ARSL

4.52e-03171192GO:0008484
GeneOntologyMolecularFunctionglutamate-gated receptor activity

GRIK3 GRIN1

4.52e-03171192GO:0004970
GeneOntologyMolecularFunctionATP hydrolysis activity

DNAH2 CHD3 DNAH7 DHX9 ABCE1 MLH1 DHX32 DNAH11

4.94e-034411198GO:0016887
GeneOntologyMolecularFunctionmonoatomic ion channel activity

NOX5 GRIK3 GRIN1 PIEZO2 KCNN3 SLC17A8 CACNA1H SLC26A11

6.25e-034591198GO:0005216
GeneOntologyMolecularFunctionlipid transporter activity

SLCO1B3 SLC22A7 SLCO1B7 PITPNM1 SLC22A8

6.42e-031961195GO:0005319
GeneOntologyBiologicalProcessmonoatomic ion transport

SLC12A6 TCN2 NOX5 SLCO1B3 COX15 CP SPG11 SLC46A1 GRIK3 GRIN1 MFSD4B SLC22A7 SLC22A12 SLCO1B7 SLC38A1 KLHL3 PIEZO2 SLC22A8 SLC20A1 SLC20A2 KCNN3 SLC17A8 CACNA1H SLC12A7 SLC26A11 SLC25A23

4.11e-08137411726GO:0006811
GeneOntologyBiologicalProcessorganic anion transport

SLCO1B3 SLC46A1 SLC22A7 SLC22A12 SLCO1B7 SLC38A1 ACSL1 SLC22A8 AGXT SLC17A8 SLC26A11 SLC16A7 SLC25A23 SLC33A1 SLC16A8

2.27e-0751511715GO:0015711
GeneOntologyBiologicalProcesscarboxylic acid transport

SLCO1B3 SLC46A1 SLC22A7 SLCO1B7 SLC38A1 ACSL1 SLC22A8 AGXT SLC17A8 SLC26A11 SLC16A7 SLC16A8

3.79e-0641011712GO:0046942
GeneOntologyBiologicalProcessorganic acid transport

SLCO1B3 SLC46A1 SLC22A7 SLCO1B7 SLC38A1 ACSL1 SLC22A8 AGXT SLC17A8 SLC26A11 SLC16A7 SLC16A8

3.98e-0641211712GO:0015849
GeneOntologyBiologicalProcessinorganic anion transport

SLC12A6 SLC25A30 SLC22A8 SLC20A1 SLC20A2 SLC17A8 SLC12A7 SLC26A11

8.74e-061801178GO:0015698
GeneOntologyBiologicalProcessmonoatomic cation transport

SLC12A6 TCN2 NOX5 COX15 CP SPG11 SLC46A1 GRIN1 MFSD4B SLC38A1 KLHL3 PIEZO2 SLC20A1 SLC20A2 KCNN3 SLC17A8 CACNA1H SLC12A7 SLC25A23

2.68e-05115711719GO:0006812
GeneOntologyBiologicalProcesstetrapyrrole metabolic process

HMBS SLCO1B3 COX15 SLC46A1 CUBN

5.95e-05731175GO:0033013
GeneOntologyBiologicalProcessinorganic anion transmembrane transport

SLC12A6 SLC20A1 SLC20A2 SLC17A8 SLC12A7 SLC26A11

1.16e-041341176GO:0098661
GeneOntologyBiologicalProcessxenobiotic metabolic process

CYP26B1 SLCO1B3 GRIN1 CYP46A1 SLC22A7 ACSL1

1.54e-041411176GO:0006805
GeneOntologyBiologicalProcessmetal ion transport

SLC12A6 TCN2 CP SPG11 SLC46A1 GRIN1 MFSD4B SLC38A1 KLHL3 SLC20A1 SLC20A2 KCNN3 SLC17A8 CACNA1H SLC12A7 SLC25A23

1.67e-04100011716GO:0030001
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

SLC12A6 TCN2 NOX5 COX15 SLC46A1 GRIK3 GRIN1 SLC38A1 PIEZO2 SLC20A1 SLC20A2 KCNN3 SLC17A8 CACNA1H SLC12A7 SLC26A11 SLC25A23

1.82e-04111511717GO:0034220
GeneOntologyBiologicalProcessammonium import across plasma membrane

SLC12A6 SLC12A7

1.90e-0441172GO:0140157
GeneOntologyBiologicalProcessmonocarboxylic acid transport

SLCO1B3 SLC22A7 SLCO1B7 ACSL1 SLC22A8 SLC16A7 SLC16A8

2.15e-042131177GO:0015718
GeneOntologyBiologicalProcessheme metabolic process

HMBS SLCO1B3 COX15 SLC46A1

2.50e-04541174GO:0042168
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

SLC12A6 TCN2 NOX5 COX15 SLC46A1 GRIN1 SLC38A1 PIEZO2 SLC20A1 SLC20A2 KCNN3 SLC17A8 CACNA1H SLC12A7 SLC25A23

2.85e-0494211715GO:0098655
GeneOntologyBiologicalProcessvitamin transport

TCN2 SLC46A1 CUBN SLC35F3

2.88e-04561174GO:0051180
GeneOntologyBiologicalProcessoligopeptide transport

SLCO1B3 SLCO1B7 SLC22A8

2.90e-04231173GO:0006857
GeneOntologyBiologicalProcessresponse to oleic acid

ACSL1 ASS1

3.15e-0451172GO:0034201
GeneOntologyBiologicalProcesscarboxylic acid transmembrane transport

SLC46A1 SLC38A1 ACSL1 SLC17A8 SLC16A7 SLC16A8

3.37e-041631176GO:1905039
GeneOntologyBiologicalProcessimport across plasma membrane

SLC12A6 SLC46A1 SLC38A1 ACSL1 SLC17A8 CACNA1H SLC12A7

3.43e-042301177GO:0098739
GeneOntologyBiologicalProcessglutamate receptor signaling pathway

KALRN GRIK3 GRIN1 GRM5

3.52e-04591174GO:0007215
GeneOntologyBiologicalProcessorganic acid transmembrane transport

SLC46A1 SLC38A1 ACSL1 SLC17A8 SLC16A7 SLC16A8

3.84e-041671176GO:1903825
GeneOntologyBiologicalProcessporphyrin-containing compound metabolic process

HMBS SLCO1B3 COX15 SLC46A1

4.53e-04631174GO:0006778
GeneOntologyBiologicalProcessionotropic glutamate receptor signaling pathway

KALRN GRIK3 GRIN1

4.71e-04271173GO:0035235
GeneOntologyBiologicalProcesssulfur compound transport

SLC22A8 SLC35F3 SLC26A11 SLC33A1

5.10e-04651174GO:0072348
GeneOntologyCellularComponentbasolateral plasma membrane

SLC12A6 SLCO1B3 SLC46A1 SLC22A7 SLCO1B7 SLC38A1 SLC22A8 SLC26A11 SLC16A7 SLC16A8

1.61e-0532012010GO:0016323
GeneOntologyCellularComponentapical plasma membrane

SLC12A6 SLC46A1 CUBN MFSD4B SLC22A7 SLC22A12 SLC38A1 FAT1 SLC22A8 SLC20A2 SLC26A11 SLC16A8

2.42e-0548712012GO:0016324
GeneOntologyCellularComponentapical part of cell

SLC12A6 ITGA8 SLC46A1 CUBN MFSD4B SLC22A7 SLC22A12 SLC38A1 FAT1 SLC22A8 SLC20A2 SLC26A11 SLC16A8

3.62e-0559212013GO:0045177
GeneOntologyCellularComponentbasal plasma membrane

SLC12A6 SLCO1B3 SLC46A1 SLC22A7 SLCO1B7 SLC38A1 SLC22A8 SLC26A11 SLC16A7 SLC16A8

3.81e-0535412010GO:0009925
GeneOntologyCellularComponentbasal part of cell

SLC12A6 SLCO1B3 SLC46A1 SLC22A7 SLCO1B7 SLC38A1 SLC22A8 SLC26A11 SLC16A7 SLC16A8

6.60e-0537812010GO:0045178
GeneOntologyCellularComponentnuclear stress granule

DHX9 SYMPK

4.83e-0461202GO:0097165
DomainMFS_dom

SLCO1B3 SLC46A1 MFSD4B SLC22A7 SLC22A12 SLCO1B7 SLC22A8 SLC17A8 SLC16A7 SLC33A1 SLC16A8

9.35e-1013411911IPR020846
DomainMFS

SLCO1B3 SLC46A1 SLC22A7 SLC22A12 SLCO1B7 SLC22A8 SLC17A8 SLC16A7 SLC16A8

2.94e-081081199PS50850
DomainMFS_1

SLC46A1 MFSD4B SLC22A7 SLC22A12 SLC22A8 SLC17A8 SLC16A7 SLC16A8

3.12e-08771198PF07690
DomainMFS

SLC46A1 MFSD4B SLC22A7 SLC22A12 SLC22A8 SLC17A8 SLC16A7 SLC16A8

3.12e-08771198IPR011701
DomainPhos_transporter

SLC20A1 SLC20A2

4.03e-0521192IPR001204
DomainPHO4

SLC20A1 SLC20A2

4.03e-0521192PF01384
DomainDynein_heavy_chain_D4_dom

DNAH2 DNAH7 DNAH11

8.72e-05141193IPR024317
DomainDynein_HC_stalk

DNAH2 DNAH7 DNAH11

8.72e-05141193IPR024743
DomainDynein_heavy_dom-2

DNAH2 DNAH7 DNAH11

8.72e-05141193IPR013602
DomainDHC_N2

DNAH2 DNAH7 DNAH11

8.72e-05141193PF08393
DomainMT

DNAH2 DNAH7 DNAH11

8.72e-05141193PF12777
DomainAAA_8

DNAH2 DNAH7 DNAH11

8.72e-05141193PF12780
DomainCadherin_tail

PCDHGB2 PCDHGA10 PCDHGA5 PCDHGA1

8.79e-05371194PF15974
DomainCadherin_CBD

PCDHGB2 PCDHGA10 PCDHGA5 PCDHGA1

8.79e-05371194IPR031904
DomainDHC_fam

DNAH2 DNAH7 DNAH11

1.09e-04151193IPR026983
DomainDynein_heavy

DNAH2 DNAH7 DNAH11

1.09e-04151193PF03028
DomainDynein_heavy_dom

DNAH2 DNAH7 DNAH11

1.09e-04151193IPR004273
DomainPCMT

PCMTD1 PCMTD2

1.20e-0431192IPR000682
DomainPCMT

PCMTD1 PCMTD2

1.20e-0431192PS01279
DomainCadherin_C

PCDHGB2 PCDHGA10 PCDHGA5 PCDHGA1

1.45e-04421194IPR032455
DomainCadherin_C_2

PCDHGB2 PCDHGA10 PCDHGA5 PCDHGA1

1.45e-04421194PF16492
DomainKCL_cotranspt

SLC12A6 SLC12A7

2.40e-0441192IPR000076
DomainAA_TRANSFER_CLASS_5

AGXT MOCOS

3.98e-0451192PS00595
DomainMCT

SLC16A7 SLC16A8

3.98e-0451192IPR004743
DomainCLTH

RANBP10 RMND5A

5.94e-0461192PF10607
DomainCRA

RANBP10 RMND5A

5.94e-0461192SM00757
DomainCTLH/CRA

RANBP10 RMND5A

5.94e-0461192IPR024964
DomainAminotrans_V_dom

AGXT MOCOS

5.94e-0461192IPR000192
DomainAminotran_5

AGXT MOCOS

5.94e-0461192PF00266
DomainCRA_dom

RANBP10 RMND5A

5.94e-0461192IPR013144
DomainCadherin_CS

PCDHGB2 PCDHGA10 PCDHGA5 PCDHGA1 FAT1

6.65e-041091195IPR020894
DomainCADHERIN_1

PCDHGB2 PCDHGA10 PCDHGA5 PCDHGA1 FAT1

7.83e-041131195PS00232
DomainCadherin

PCDHGB2 PCDHGA10 PCDHGA5 PCDHGA1 FAT1

7.83e-041131195PF00028
DomainCadherin_2

PCDHGB2 PCDHGA10 PCDHGA5 PCDHGA1

7.86e-04651194PF08266
DomainCadherin_N

PCDHGB2 PCDHGA10 PCDHGA5 PCDHGA1

7.86e-04651194IPR013164
DomainCADHERIN_2

PCDHGB2 PCDHGA10 PCDHGA5 PCDHGA1 FAT1

8.15e-041141195PS50268
Domain-

PCDHGB2 PCDHGA10 PCDHGA5 PCDHGA1 FAT1

8.15e-0411411952.60.40.60
DomainSLC12A_fam

SLC12A6 SLC12A7

8.28e-0471192IPR004842
DomainCA

PCDHGB2 PCDHGA10 PCDHGA5 PCDHGA1 FAT1

8.48e-041151195SM00112
DomainCadherin-like

PCDHGB2 PCDHGA10 PCDHGA5 PCDHGA1 FAT1

8.81e-041161195IPR015919
DomainCadherin

PCDHGB2 PCDHGA10 PCDHGA5 PCDHGA1 FAT1

9.52e-041181195IPR002126
DomainSLC12_C

SLC12A6 SLC12A7

1.10e-0381192IPR018491
DomainDHC_N1

DNAH2 DNAH11

1.10e-0381192PF08385
DomainSLC12

SLC12A6 SLC12A7

1.10e-0381192PF03522
DomainDynein_heavy_dom-1

DNAH2 DNAH11

1.10e-0381192IPR013594
DomainOrgcat_transp/SVOP

SLC22A7 SLC22A8

1.41e-0391192IPR004749
DomainCTLH

RANBP10 RMND5A

1.41e-0391192SM00668
DomainANF_lig-bd_rcpt

GRIK3 GRIN1 GRM5

1.67e-03371193IPR001828
DomainANF_receptor

GRIK3 GRIN1 GRM5

1.67e-03371193PF01094
DomainCTLH_C

RANBP10 RMND5A

1.75e-03101192IPR006595
DomainCTLH

RANBP10 RMND5A

1.75e-03101192PS50897
DomainPeripla_BP_I

GRIK3 GRIN1 GRM5

1.95e-03391193IPR028082
Domain-

SEPSECS AGXT MOCOS

1.95e-033911933.40.640.10
DomainPyrdxlP-dep_Trfase

SEPSECS AGXT MOCOS

2.25e-03411193IPR015424
DomainPyrdxlP-dep_Trfase_major_sub1

SEPSECS AGXT MOCOS

2.25e-03411193IPR015421
DomainOA_transporter

SLCO1B3 SLCO1B7

2.55e-03121192IPR004156
DomainOATP

SLCO1B3 SLCO1B7

2.55e-03121192PF03137
Domain-

GART SYN2

3.00e-031311923.40.50.20
DomainATPase_dyneun-rel_AAA

DNAH2 DNAH11

3.48e-03141192IPR011704
DomainPreATP-grasp_dom

GART SYN2

3.48e-03141192IPR016185
DomainAAA_5

DNAH2 DNAH11

3.48e-03141192PF07728
Domain-

GART SYN2

4.00e-031511923.30.1490.20
DomainSulfatase_CS

ARSH ARSL

4.56e-03161192IPR024607
DomainSULFATASE_1

ARSH ARSL

5.14e-03171192PS00523
DomainDUF1605

DHX9 DHX32

5.14e-03171192IPR011709
DomainSULFATASE_2

ARSH ARSL

5.14e-03171192PS00149
DomainOB_NTP_bind

DHX9 DHX32

5.14e-03171192PF07717
DomainSulfatase

ARSH ARSL

5.76e-03181192PF00884
DomainLig_chan-Glu_bd

GRIK3 GRIN1

5.76e-03181192PF10613
DomainATP_grasp_subdomain_1

GART SYN2

5.76e-03181192IPR013815
DomainGlu/Gly-bd

GRIK3 GRIN1

5.76e-03181192IPR019594
DomainLig_chan-Glu_bd

GRIK3 GRIN1

5.76e-03181192SM00918
Domain-

GART SYN2

5.76e-031811923.30.470.20
DomainIontro_rcpt

GRIK3 GRIN1

5.76e-03181192IPR001320
DomainIono_rcpt_met

GRIK3 GRIN1

5.76e-03181192IPR001508
DomainHA2

DHX9 DHX32

5.76e-03181192SM00847
DomainHA2

DHX9 DHX32

5.76e-03181192PF04408
DomainLig_chan

GRIK3 GRIN1

5.76e-03181192PF00060
DomainSulfatase_N

ARSH ARSL

5.76e-03181192IPR000917
DomainHelicase-assoc_dom

DHX9 DHX32

5.76e-03181192IPR007502
DomainPBPe

GRIK3 GRIN1

5.76e-03181192SM00079
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC12A6 SLCO1B3 CP SLC22A7 SLC22A12 SLCO1B7 SLC38A1 SLC22A8 SLC20A1 SLC20A2 SLC17A8 SLC12A7 SLC26A11 SLC16A7 SLC33A1 SLC16A8

3.75e-122389416MM15076
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC12A6 SLCO1B3 CP MFSD4B SLC22A7 SLC22A12 SLC38A1 SLC22A8 SLC20A1 SLC20A2 SLC17A8 SLC12A7 SLC26A11 SLC16A7 SLC33A1 SLC16A8

7.46e-122499416M5988
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC12A6 RAF1 SLCO1B3 CP SLC46A1 CUBN MFSD4B SLC22A7 SLC22A12 SLC38A1 SLC22A8 LIPG SLC20A1 SLC20A2 SLC17A8 SLC12A7 SLC26A11 SLC16A7 SLC33A1 SLC16A8

6.12e-087369420M27287
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC12A6 RAF1 SLCO1B3 CP SLC46A1 SLC22A7 SLC22A12 SLCO1B7 SLC38A1 SLC22A8 LIPG SLC20A1 SLC20A2 SLC17A8 SLC12A7 SLC26A11 SLC16A7 SLC33A1 SLC16A8

9.19e-086819419MM14985
PathwayREACTOME_SLC_TRANSPORTER_DISORDERS

SLC12A6 SLCO1B3 CP SLC22A12 SLC20A2 SLC17A8 NUP93 SLC33A1

3.01e-0799948M27474
PathwayREACTOME_ORGANIC_ANION_TRANSPORT

SLC22A7 SLC22A12 SLC22A8

2.84e-065943M27469
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC12A6 SLC38A1 SLC20A1 SLC20A2 SLC17A8 SLC12A7 SLC26A11

7.54e-06108947M823
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC12A6 SLC38A1 SLC20A1 SLC20A2 SLC17A8 SLC12A7 SLC26A11

8.01e-06109947MM15074
PathwayREACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS

CP SLC22A7 SLC22A12 SLC22A8 SLC16A7 SLC16A8

1.12e-0576946MM15072
PathwayREACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS

CP SLC22A7 SLC22A12 SLC22A8 SLC16A7 SLC16A8

2.00e-0584946M27334
PathwayREACTOME_DISORDERS_OF_TRANSMEMBRANE_TRANSPORTERS

SLC12A6 SLCO1B3 CP SLC22A12 SLC20A2 SLC17A8 NUP93 SLC33A1

2.34e-05177948M27476
PathwayREACTOME_METABOLISM_OF_PORPHYRINS

HMBS SLCO1B3 COX15 SLCO1B7

5.78e-0532944MM14719
PathwayREACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT

SLC22A7 SLC22A12 SLC22A8

6.05e-0512943MM15192
PathwayREACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT

SLC22A7 SLC22A12 SLC22A8

1.23e-0415943M888
PathwayREACTOME_METABOLISM_OF_LIPIDS

PRKD2 MBOAT1 SLCO1B3 ACAD10 CUBN PEX11A PTGDS CYP46A1 GGT5 PITPNM1 ARSH ACSL1 RGL1 VAC14 ARSL

1.36e-047579415M27451
PathwayWP_MALE_INFERTILITY

CYP26B1 TCN2 SLC46A1 CXXC1 MLH1 SLC16A7

4.13e-04145946M39856
PathwayREACTOME_SODIUM_COUPLED_PHOSPHATE_COTRANSPORTERS

SLC20A1 SLC20A2

4.34e-045942M27345
PathwayREACTOME_SODIUM_COUPLED_PHOSPHATE_COTRANSPORTERS

SLC20A1 SLC20A2

4.34e-045942MM15085
PathwayWP_PURINE_METABOLISM_AND_RELATED_DISORDERS

GART GRM5 MOCOS

4.62e-0423943M39766
PathwayREACTOME_PROTON_COUPLED_MONOCARBOXYLATE_TRANSPORT

SLC16A7 SLC16A8

6.48e-046942MM17217
PathwayREACTOME_PROTON_COUPLED_MONOCARBOXYLATE_TRANSPORT

SLC16A7 SLC16A8

6.48e-046942M27355
PathwayREACTOME_METABOLISM_OF_PORPHYRINS

HMBS SLCO1B3 COX15

7.48e-0427943M1088
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_RETROGRADE_AXONAL_TRANSPORT

DNAH2 DNAH7 DNAH11

7.48e-0427943M47755
PathwayREACTOME_CATION_COUPLED_CHLORIDE_COTRANSPORTERS

SLC12A6 SLC12A7

9.04e-047942M27339
PathwayREACTOME_CATION_COUPLED_CHLORIDE_COTRANSPORTERS

SLC12A6 SLC12A7

9.04e-047942MM15081
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

RAF1 AMBRA1 COX15 PAPLN CHD3 TGFBI SMG8 ABCE1 MLH1 SLC12A7 TASOR SLC33A1 MOCOS

4.24e-076501201338777146
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

SLC12A6 TREX1 WDR83 SPG11 SLC46A1 CPD ACAD10 TGFBI FAT1 ARSL APH1A SLC20A1 NUP93 SLC12A7 SLC33A1 SYMPK

8.02e-0710611201633845483
Pubmed

Molecular physiology of renal organic anion transporters.

SLC22A7 SLC22A12 SLC22A8

1.12e-0513120316403838
Pubmed

Identification of a novel murine organic anion transporter family member, OAT6, expressed in olfactory mucosa.

SLC22A7 SLC22A12 SLC22A8

1.12e-0513120315369770
Pubmed

Germline polymorphisms in the one-carbon metabolism pathway and DNA methylation in colorectal cancer.

TCN2 GART MLH1

1.12e-0513120319936946
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

KALRN CP CUBN GFRA1 SLC22A12 EEF2 FAT1 ARSL SLC22A8 ASS1 TOLLIP GCA SLC26A11 CPVL

1.14e-0510161201419056867
Pubmed

Phosphate-dependent FGF23 secretion is modulated by PiT2/Slc20a2.

SLC20A1 SLC20A2

1.18e-052120229551636
Pubmed

Sodium-dependent phosphate cotransporters and phosphate-induced calcification of vascular smooth muscle cells: redundant roles for PiT-1 and PiT-2.

SLC20A1 SLC20A2

1.18e-052120223968976
Pubmed

Slc20a1 and Slc20a2 regulate neuronal plasticity and cognition independently of their phosphate transport ability.

SLC20A1 SLC20A2

1.18e-052120238195526
Pubmed

Mapping of the minimal inorganic phosphate transporting unit of human PiT2 suggests a structure universal to PiT-related proteins from all kingdoms of life.

SLC20A1 SLC20A2

1.18e-052120221586110
Pubmed

Direct interaction enables cross-talk between ionotropic and group I metabotropic glutamate receptors.

GRIN1 GRM5

1.18e-052120218182392
Pubmed

Two highly conserved glutamate residues critical for type III sodium-dependent phosphate transport revealed by uncoupling transport function from retroviral receptor function.

SLC20A1 SLC20A2

1.18e-052120212205090
Pubmed

SLC12A ion transporter mutations in sporadic and familial human congenital hydrocephalus.

SLC12A6 SLC12A7

1.18e-052120231393094
Pubmed

Genetic Variability in the Iron Homeostasis Pathway and Patient Outcomes After Aneurysmal Subarachnoid Hemorrhage.

CP CUBN

1.18e-052120232246437
Pubmed

Mouse organic anion transporter 2 and 3 (mOAT2/3[Slc22a7/8]) mediates the renal transport of bumetanide.

SLC22A7 SLC22A8

1.18e-052120216256982
Pubmed

A family of retroviruses that utilize related phosphate transporters for cell entry.

SLC20A1 SLC20A2

1.18e-05212027966619
Pubmed

Inorganic phosphate regulates Glvr-1 and -2 expression: role of calcium and ERK1/2.

SLC20A1 SLC20A2

1.18e-052120219232318
Pubmed

Cloning and characterization of KCC3 and KCC4, new members of the cation-chloride cotransporter gene family.

SLC12A6 SLC12A7

1.18e-052120210347194
Pubmed

Slc20a1/Pit1 and Slc20a2/Pit2 are essential for normal skeletal myofiber function and survival.

SLC20A1 SLC20A2

1.18e-052120232080237
Pubmed

Activation of NMDA receptors reduces metabotropic glutamate receptor-induced long-term depression in the nucleus accumbens via a CaMKII-dependent mechanism.

GRIN1 GRM5

1.18e-052120222947307
Pubmed

Targeting Vesicular Glutamate Transporter Machinery: Implications on Metabotropic Glutamate Receptor 5 Signaling and Behavior.

GRM5 SLC17A8

1.18e-052120232873747
Pubmed

Deciphering PiT transport kinetics and substrate specificity using electrophysiology and flux measurements.

SLC20A1 SLC20A2

1.18e-052120217494632
Pubmed

Cell-surface receptors for gibbon ape leukemia virus and amphotropic murine retrovirus are inducible sodium-dependent phosphate symporters.

SLC20A1 SLC20A2

1.18e-05212028041748
Pubmed

Characterization of transport mechanisms and determinants critical for Na+-dependent Pi symport of the PiT family paralogs human PiT1 and PiT2.

SLC20A1 SLC20A2

1.18e-052120216790504
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH2 DNAH7 DNAH11

1.42e-051412039373155
Pubmed

Excitatory glutamate is essential for development and maintenance of the piloneural mechanoreceptor.

GRIK3 GRIN1 GRM5

1.77e-0515120322241839
Pubmed

ARMC5 is part of an RPB1-specific ubiquitin ligase implicated in adrenal hyperplasia.

RAF1 GART DHX9 ACSL1 EEF2 NUP93

2.52e-05166120635687106
Pubmed

Quantitative Protein Expression in the Human Retinal Pigment Epithelium: Comparison Between Apical and Basolateral Plasma Membranes With Emphasis on Transporters.

SLC46A1 SLC22A8 SLC16A8

3.15e-0518120331791063
Pubmed

Mapping HSA 3 loci in cattle: additional support for the ancestral synteny of HSA 3 and 21.

RAF1 GART CP

3.15e-051812031783381
Pubmed

Characterization of organic anion transporting polypeptide 1b2-null mice: essential role in hepatic uptake/toxicity of phalloidin and microcystin-LR.

SLCO1B3 SLCO1B7

3.53e-053120218296417
Pubmed

Interaction Between Sex and Organic Anion-Transporting Polypeptide 1b2 on the Pharmacokinetics of Regorafenib and Its Metabolites Regorafenib-N-Oxide and Regorafenib-Glucuronide in Mice.

SLCO1B3 SLCO1B7

3.53e-053120230955241
Pubmed

Influence of drug formulation on OATP1B-mediated transport of paclitaxel.

SLCO1B3 SLCO1B7

3.53e-053120224755470
Pubmed

IGF-1 upregulates electroneutral K-Cl cotransporter KCC3 and KCC4 which are differentially required for breast cancer cell proliferation and invasiveness.

SLC12A6 SLC12A7

3.53e-053120217133354
Pubmed

OATP1B2 deficiency protects against paclitaxel-induced neurotoxicity.

SLCO1B3 SLCO1B7

3.53e-053120229337310
Pubmed

Expression of Oatp2 in the Brain and Liver of Alzheimer Disease Mouse Model.

SLCO1B3 SLCO1B7

3.53e-053120231967785
Pubmed

Multiple organic anion transporters contribute to net renal excretion of uric acid.

SLC22A12 SLC22A8

3.53e-053120218270321
Pubmed

Four novel interaction partners demonstrate diverse modulatory effects on voltage-gated CaV2.2 Ca2+ channels.

PTGDS SLC38A1

3.53e-053120230612149
Pubmed

Tex261 modulates the excitotoxic cell death induced by N-methyl-D-aspartate (NMDA) receptor activation.

TEX261 GRIN1

3.53e-053120217803966
Pubmed

Role of the murine organic anion-transporting polypeptide 1b2 (Oatp1b2) in drug disposition and hepatotoxicity.

SLCO1B3 SLCO1B7

3.53e-053120218492796
Pubmed

Differential Expression of OATP1B3 Mediates Unconjugated Testosterone Influx.

SLCO1B3 SLCO1B7

3.53e-053120228389619
Pubmed

Organic anion transporting polypeptide 1B transporters modulate hydroxyurea pharmacokinetics.

SLCO1B3 SLCO1B7

3.53e-053120223986199
Pubmed

Targeted disruption of murine organic anion-transporting polypeptide 1b2 (Oatp1b2/Slco1b2) significantly alters disposition of prototypical drug substrates pravastatin and rifampin.

SLCO1B3 SLCO1B7

3.53e-053120218413659
Pubmed

Organic anion-transporting polypeptide 1b2 (Oatp1b2) is important for the hepatic uptake of unconjugated bile acids: Studies in Oatp1b2-null mice.

SLCO1B3 SLCO1B7

3.53e-053120220949553
Pubmed

Human organic anion transporter 2 is distinct from organic anion transporters 1 and 3 with respect to transport function.

SLC22A7 SLC22A8

3.53e-053120226377792
Pubmed

Molecular evidence for a role for K(+)-Cl(-) cotransporters in the kidney.

SLC12A6 SLC12A7

3.53e-053120224089410
Pubmed

Altered surface mGluR5 dynamics provoke synaptic NMDAR dysfunction and cognitive defects in Fmr1 knockout mice.

GRIN1 GRM5

3.53e-053120229062097
Pubmed

A dominant negative mutant of the KCC1 K-Cl cotransporter: both N- and C-terminal cytoplasmic domains are required for K-Cl cotransport activity.

SLC12A6 SLC12A7

3.53e-053120211551954
Pubmed

Insulin-like growth factor 1 stimulates KCl cotransport, which is necessary for invasion and proliferation of cervical cancer and ovarian cancer cells.

SLC12A6 SLC12A7

3.53e-053120215262997
Pubmed

Identification, expression, and functional characterization of full-length and splice variants of murine organic anion transporting polypeptide 1b2.

SLCO1B3 SLCO1B7

3.53e-053120219400585
Pubmed

Synergistic interaction between genetics and disease on pravastatin disposition.

SLCO1B3 SLCO1B7

3.53e-053120224613363
Pubmed

Full-length cDNA cloning and genomic organization of the mouse liver-specific organic anion transporter-1 (lst-1).

SLCO1B3 SLCO1B7

3.53e-053120210833452
Pubmed

Ammonium transport and pH regulation by K(+)-Cl(-) cotransporters.

SLC12A6 SLC12A7

3.53e-053120212657561
Pubmed

K-Cl cotransporter gene expression during human and murine erythroid differentiation.

SLC12A6 SLC12A7

3.53e-053120221733850
Pubmed

Cytoskeletal scaffolding proteins interact with Lynch-Syndrome associated mismatch repair protein MLH1.

PTGDS EEF2 ASS1 MLH1

4.31e-0556120420706999
Pubmed

Impact of Oatp1c1 deficiency on thyroid hormone metabolism and action in the mouse brain.

SLCO1B3 SLCO1B7

7.05e-054120222294745
Pubmed

Organic anion transporting polypeptide 1a/1b-knockout mice provide insights into hepatic handling of bilirubin, bile acids, and drugs.

SLCO1B3 SLCO1B7

7.05e-054120220644253
Pubmed

Population-Specific Resequencing Associates the ATP-Binding Cassette Subfamily C Member 4 Gene With Gout in New Zealand Māori and Pacific Men.

SLC22A7 SLC22A8

7.05e-054120228371506
Pubmed

Protection against phalloidin-induced liver injury by oleanolic acid involves Nrf2 activation and suppression of Oatp1b2.

SLCO1B3 SLCO1B7

7.05e-054120225280775
Pubmed

Human organic anion transporters mediate the transport of tetracycline.

SLC22A7 SLC22A8

7.05e-054120211855680
Pubmed

Distribution of organic anion transporters NaDC3 and OAT1-3 along the human nephron.

SLC22A7 SLC22A8

7.05e-054120227053689
Pubmed

Neurochemically and Hodologically Distinct Ascending VGLUT3 versus Serotonin Subsystems Comprise the r2-Pet1 Median Raphe.

PIEZO2 SLC17A8

7.05e-054120233547164
Pubmed

Influence of K-Cl cotransporter activity on activation of volume-sensitive Cl- channels in human osteoblasts.

SLC12A6 SLC12A7

7.05e-054120212637262
Pubmed

Contribution of Organic Anion-Transporting Polypeptides 1A/1B to Doxorubicin Uptake and Clearance.

SLCO1B3 SLCO1B7

7.05e-054120227777271
Pubmed

Glutamate can act as a signaling molecule in mouse preimplantation embryos†.

GRIK3 GRIN1 GRM5

7.69e-0524120335746896
Pubmed

Comparative DNA sequence analysis of mouse and human protocadherin gene clusters.

PCDHGB2 PCDHGA10 PCDHGA5 PCDHGA1

9.25e-0568120411230163
Pubmed

A striking organization of a large family of human neural cadherin-like cell adhesion genes.

PCDHGB2 PCDHGA10 PCDHGA5 PCDHGA1

1.16e-0472120410380929
Pubmed

Localization of the synapsin II (SYN2) gene to human chromosome 3 and mouse chromosome 6.

RAF1 SYN2

1.17e-04512028530057
Pubmed

Genetics and molecular biology of brain calcification.

TREX1 SLC20A2

1.17e-045120225906927
Pubmed

OATP1A/1B transporters affect irinotecan and SN-38 pharmacokinetics and carboxylesterase expression in knockout and humanized transgenic mice.

SLCO1B3 SLCO1B7

1.17e-045120224194565
Pubmed

Genetic expression of monocarboxylate transporters during human and murine oocyte maturation and early embryonic development.

SLC16A7 SLC16A8

1.17e-045120212056458
Pubmed

The GDNF-GFRα1 complex promotes the development of hippocampal dendritic arbors and spines via NCAM.

GRIN1 GFRA1

1.17e-045120227707798
Pubmed

Developmentally regulated expression of organic ion transporters NKT (OAT1), OCT1, NLT (OAT2), and Roct.

SLC22A7 SLC22A8

1.17e-045120210751225
Pubmed

Cysteine 159 delineates a hinge region of the alternating access monocarboxylate transporter 1 and is targeted by cysteine-modifying inhibitors.

SLC16A7 SLC16A8

1.17e-045120233999492
Pubmed

Comparative analysis of cobalamin binding kinetics and ligand protection for intrinsic factor, transcobalamin, and haptocorrin.

TCN2 CUBN

1.17e-045120211788601
Pubmed

Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.

TEX261 CUBN PTGDS SLC38A1 APH1A CACNA1H SLC26A11 CPVL

1.29e-04430120816303743
Pubmed

Cadherin superfamily genes: functions, genomic organization, and neurologic diversity.

PCDHGB2 PCDHGA10 PCDHGA5 PCDHGA1

1.29e-0474120410817752
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

SLC12A6 PCDHGB2 PCDHGA10 PCDHGA5 PCDHGA1 EML6 DNAH2 SPG11 CHD3 TEX14 PEX11A CXXC1 DNAJB14 EEF2 TASOR

1.36e-0414421201535575683
Pubmed

LINC01554-Mediated Glucose Metabolism Reprogramming Suppresses Tumorigenicity in Hepatocellular Carcinoma via Downregulating PKM2 Expression and Inhibiting Akt/mTOR Signaling Pathway.

DNAH2 DHX9 TGFBI EEF2 ASS1

1.38e-04142120530809309
Pubmed

Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members.

PCDHGB2 PCDHGA10 PCDHGA5 PCDHGA1

1.50e-0477120410835267
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

MBOAT1 KALRN BCAS3 DNAH2 DNAH7 DNAH11

1.64e-04233120637704626
Pubmed

Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes.

PCDHGB2 PCDHGA10 PCDHGA5 PCDHGA1

1.74e-0480120410716726
Pubmed

Complete OATP1B1 and OATP1B3 deficiency causes human Rotor syndrome by interrupting conjugated bilirubin reuptake into the liver.

SLCO1B3 SLCO1B7

1.75e-046120222232210
Pubmed

Basigin (CD147) is the target for organomercurial inhibition of monocarboxylate transporter isoforms 1 and 4: the ancillary protein for the insensitive MCT2 is EMBIGIN (gp70).

SLC16A7 SLC16A8

1.75e-046120215917240
Pubmed

The actin-binding protein Filamin-A interacts with the metabotropic glutamate receptor type 7.

GRIK3 GRM5

1.75e-046120211943148
Pubmed

Human organic anion transporters and human organic cation transporters mediate renal transport of prostaglandins.

SLC22A7 SLC22A8

1.75e-046120211907186
Pubmed

Analysis of DNA methylation and histone modification profiles of liver-specific transporters.

SLCO1B3 SLCO1B7

1.75e-046120219047482
Pubmed

Generation of mouse conditional and null alleles of the type III sodium-dependent phosphate cotransporter PiT-1.

SLC20A1 SLC20A2

1.75e-046120219882669
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

GART AMBRA1 POGZ CXXC1 DHX9 ACSL1 SMG8 EEF2 TFB1M ABCE1 NAT10 ASS1 MLH1 NUP93

2.44e-0413531201429467282
Pubmed

Modular construction of a signaling scaffold: MORG1 interacts with components of the ERK cascade and links ERK signaling to specific agonists.

RAF1 WDR83

2.45e-047120215118098
Pubmed

ATR kinase activation mediated by MutSalpha and MutLalpha in response to cytotoxic O6-methylguanine adducts.

TREX1 MLH1

2.45e-047120216713580
Pubmed

Isolation of several human axonemal dynein heavy chain genes: genomic structure of the catalytic site, phylogenetic analysis and chromosomal assignment.

DNAH2 DNAH11

2.45e-04712029256245
Pubmed

PIEZO2 mediates ultrasonic hearing via cochlear outer hair cells in mice.

PIEZO2 SLC17A8

2.45e-047120234244441
Pubmed

Identification of novel cadherins expressed in human melanoma cells.

PCDHGA5 FAT1

2.45e-04712029182820
Pubmed

Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia.

DNAH2 DNAH11

2.45e-047120231178125
Pubmed

Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair.

GART WDR83 POGZ DHX9 EEF2 MLH1 SYMPK

2.50e-04357120737059091
Pubmed

Disruption of KCC2 reveals an essential role of K-Cl cotransport already in early synaptic inhibition.

SLC12A6 SLC12A7

3.26e-048120211395011
Pubmed

The WNK-regulated SPAK/OSR1 kinases directly phosphorylate and inhibit the K+-Cl- co-transporters.

SLC12A6 SLC12A7

3.26e-048120224393035
Pubmed

Similar effects of all WNK3 variants on SLC12 cotransporters.

SLC12A6 SLC12A7

3.26e-048120221613606
Pubmed

Systematic analysis of glutamatergic neurotransmission genes in alcohol dependence and adolescent risky drinking behavior.

GRIN1 GRM5

3.26e-048120218606955
Pubmed

Functional Equivalence of the SOX2 and SOX3 Transcription Factors in the Developing Mouse Brain and Testes.

GFRA1 TGFBI

3.26e-048120228515211
Cytoband5q31

PCDHGB2 PCDHGA10 PCDHGA5 PCDHGA1 TGFBI KLHL3

6.27e-0711512065q31
CytobandEnsembl 112 genes in cytogenetic band chr5q31

PCDHGB2 PCDHGA10 PCDHGA5 PCDHGA1 TGFBI KLHL3

1.40e-042981206chr5q31
Cytoband18q12

CXXC1 MOCOS

5.19e-0413120218q12
Cytoband4q35

ACSL1 FAT1

6.96e-041512024q35
Cytoband3p25

RAF1 SYN2

8.98e-041712023p25
GeneFamilySolute carriers

SLC12A6 SLCO1B3 SLC25A30 SLC46A1 SLC22A7 SLC22A12 SLCO1B7 SLC38A1 SLC22A8 SLC35F3 SLC20A1 SLC20A2 SLC17A8 SLC12A7 SLC26A11 SLC16A7 SLC25A23 SLC33A1 SLC16A8

2.62e-143958619752
GeneFamilyDyneins, axonemal

DNAH2 DNAH7 DNAH11

6.73e-0517863536
GeneFamilyClustered protocadherins

PCDHGB2 PCDHGA10 PCDHGA5 PCDHGA1

2.44e-046486420
GeneFamilyDEAH-box helicases

DHX9 DHX32

2.57e-0316862500
GeneFamilySulfatases

ARSH ARSL

3.26e-0318862410
GeneFamilyCarboxypeptidases

CPD CPVL

4.43e-03218621321
CoexpressionAtlaskidney_adult_RenalCortexMixed_Std_k-means-cluster#4_top-relative-expression-ranked_500

TCN2 CUBN PGAP6 ACSL1 SLC22A8 ASS1 SLC16A7

1.24e-051421157gudmap_kidney_adult_RenalCortexMixed_Std_k4_500
CoexpressionAtlaskidney_adult_CortVasc_Tie2_k-means-cluster#1_top-relative-expression-ranked_1000

TCN2 SLC25A30 CUBN PGAP6 SLC22A7 ACSL1 SLC22A8 ASS1 STK38L

5.38e-053141159gudmap_kidney_adult_CortVasc_Tie2_k1_1000
CoexpressionAtlaskidney_adult_JuxtaGlom_Ren1_k-means-cluster#1_top-relative-expression-ranked_200

TCN2 ACSL1 SLC22A8 ASS1 SLC16A7

5.81e-05761155gudmap_kidney_adult_JuxtaGlom_Ren1_k1_200
CoexpressionAtlaskidney_adult_JuxtaGlom_Ren1_k-means-cluster#2_top-relative-expression-ranked_1000

TCN2 CUBN PGAP6 SLC22A12 ACSL1 SLC22A8 ASS1 GCA SLC16A7

8.43e-053331159gudmap_kidney_adult_JuxtaGlom_Ren1_k2_1000
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDHGA10 EML6 GRIK3 PGAP6 KLHL3 MLH1 DNAH11

3.30e-0716512071703d3eb644b3c743ad3c5532b1d29ea010c79c8
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EML6 GRM5 FAT1 SLC35F3 LIPG CPVL DNAH11

5.10e-071761207327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCellfacs-Kidney-nan-18m-Epithelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCN2 CUBN SLC22A7 SLC22A12 ACSL1 SLC22A8 ASS1

5.30e-0717712077f58286fc8797e9bdcf8ece0849f55680905955d
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC12A6 CUBN SLC22A7 SLC22A12 SLC22A8 ASS1 SYN2

6.63e-07183120784b64cf728629c3af9a8d2ed15b93adf562c54b8
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC12A6 PAPLN CUBN SLC22A7 SLC22A12 SLC22A8 ASS1

7.94e-071881207f3edcefeef2ce19086032d98b243c02a6d542b38
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC12A6 PAPLN CUBN SLC22A7 SLC22A12 SLC22A8 ASS1

7.94e-0718812070792432cd4c564dea1102241ea9884f7ced7658c
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

EML6 GRM5 DNAH7 FAT1 LIPG CPVL DNAH11

8.23e-071891207904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCellNS-critical-d_0-4-Myeloid-pDC|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PTGDS CYP46A1 SLC35F3 ABCE1 MLH1 KCNN3

2.62e-0614412060fde5cd82df9b90aefde19275cff6c2ec3c9d5cb
ToppCelldroplet-Liver-Hepatocytes-24m-Epithelial-Hepatocyte_(Pericentral_and_Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLCO1B3 CP ACSL1 ASS1 AGXT SLC25A23

3.86e-061541206a5289000597068ee8d559f89bce7bce31f35dd57
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC12A6 CUBN SLC22A7 SLC22A12 SLC22A8 ASS1

7.05e-061711206f5014e3c387fe3118944af392abe10d6b9b0abab
ToppCellfacs-Kidney-nan-24m-Epithelial-kidney_collecting_duct_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCN2 CHD3 CUBN PGAP6 SLC22A8 ASS1

8.58e-0617712069c7c6824b9011363851f084a500d665f025b026e
ToppCellfacs-Kidney-nan-24m-Epithelial-kidney_collecting_duct_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCN2 CHD3 CUBN PGAP6 SLC22A8 ASS1

8.58e-0617712062bf639e9e801e5144462ffc957f5739e0dfcd500
ToppCellfacs-Kidney-nan-3m-Epithelial-kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KALRN KLHL3 AGXT GCA SLC16A7 DNAH11

9.44e-061801206fc5b9d0e3215652e490ca72d69f776e9725608b2
ToppCellfacs-Kidney-nan-3m-Epithelial-kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KALRN KLHL3 AGXT GCA SLC16A7 DNAH11

9.44e-0618012066763b22f2383931c747b37cd0ae2f60b08f64d90
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PAPLN CUBN SLC22A7 SLC22A12 SLC22A8 ASS1

9.75e-0618112069542c19edc9bd2cba68c01c2a8407705398e3011
ToppCellfacs-Kidney-nan-18m-Epithelial-kidney_collecting_duct_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCN2 CUBN SLC22A12 ACSL1 SLC22A8 ASS1

9.75e-061811206bec7076efe94898213a62db72d171d737949977e
ToppCellfacs-Kidney-nan-18m-Epithelial-kidney_collecting_duct_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCN2 CUBN SLC22A12 ACSL1 SLC22A8 ASS1

9.75e-061811206cf149b30b814cf87c9e923ef502cadf7fe4a3597
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PAPLN CUBN SLC22A7 SLC22A12 SLC22A8 ASS1

9.75e-0618112068f04f8cac5d705dc5f6cf6f4516d6e45b0aa4ae5
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC12A6 CUBN SLC22A7 SLC22A12 SLC22A8 ASS1

1.04e-051831206facd6dbe0851b537d70a899ac7485714ab27d071
ToppCellfacs-Liver-Hepatocytes-24m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACAD10 GFRA1 ACSL1 SLC20A2 SLC17A8 SLC16A7

1.04e-051831206d0721c6aa426953a520d40e976b6e65aa7ca65e8
ToppCelldroplet-Kidney-nan-21m-Epithelial-Epcam____kidney_proximal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCN2 CUBN SLC22A12 ACSL1 SLC22A8 ASS1

1.07e-0518412063d7dd193a0826cc7a4e454a29236a16c315e5965
ToppCelldroplet-Kidney-nan-21m-Epithelial-kidney_proximal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCN2 CUBN SLC22A12 ACSL1 SLC22A8 ASS1

1.07e-05184120645577ff91c3b2b303acd97239dde2463ea7a429c
ToppCellCOVID-19-kidney-PCT-S1/S2|kidney / Disease (COVID-19 only), tissue and cell type

CUBN SLC22A7 SLC22A12 SLC22A8 ASS1 SYN2

1.07e-051841206dc71f22583fc54b89b242cbb602f4bbe86f576ec
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

EML6 GRM5 FAT1 SLC35F3 CPVL DNAH11

1.14e-0518612065c4ffe4e4d5536ae9f8794277fe032c693e7dd56
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PAPLN CUBN SLC22A7 SLC22A12 SLC22A8 ASS1

1.14e-0518612065784d255e9ca449d375d81938d0fbbd8a7eb44f6
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c5-CD16|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TCN2 HMBS ACSL1 TGFBI SLC26A11 CPVL

1.17e-0518712065917bdfe84cf5941e21b415aebbab3090cc5d576
ToppCell(0)_Myeloid-(011)_pDC|(0)_Myeloid / immune cells in Peripheral Blood (logTPM normalization)

PAPLN GRIN1 PTGDS CYP46A1 SLC38A1 SLC35F3

1.21e-051881206a81b5d840490d6a636fe168f8cff2c4984369f09
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PAPLN CUBN SLC22A7 SLC22A12 SLC22A8 ASS1

1.25e-051891206204ab61ae606b2d9be0cb6bf6a83a011740693a8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PAPLN CUBN SLC22A7 SLC22A12 SLC22A8 ASS1

1.25e-05189120613fd07cc408a9486f61a7b2c3a132c52d14b438d
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-hematologic-erythrocytic|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

HMBS SLCO1B3 CP HSD17B6 ASS1 AGXT

1.25e-0518912067899af78b273d9c7f029d52f7e0cf6df4da41f5e
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-hematologic-erythrocytic-erythrocyte|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

HMBS SLCO1B3 CP HSD17B6 ASS1 AGXT

1.28e-051901206a34293601aefe5fb5c400c14091294b9ddaa195b
ToppCelldroplet-Mammary_Gland-nan-21m-Epithelial-luminal_epithelial_cell_of_mammary_gland|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MBOAT1 FAT1 PIEZO2 SLC35F3 SYN2 DNAH11

1.32e-051911206b94e66ac71e73f46b0323d424e7b8b906751d584
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMTC2 GFRA1 ACSL1 PIEZO2 KCNN3 GCA

1.40e-05193120696c85b250d04b5f400512097d925061c6dc2906b
ToppCellmedial-2-Hematologic-EREG+_Dendritic|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PCDHGB2 NOX5 ACSL1 TGFBI STK38L CPVL

1.44e-051941206b2b4e4c3ac0df0d9f17b930ffb60c0fd85b3dd78
ToppCellmedial-Hematologic-EREG+_Dendritic-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PCDHGB2 NOX5 ACSL1 TGFBI STK38L CPVL

1.44e-05194120615f3b6b6579e388d0820f05e93a77ee1634bd6c3
ToppCellmedial-Hematologic-EREG+_Dendritic|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PCDHGB2 NOX5 ACSL1 TGFBI STK38L CPVL

1.44e-0519412061f3d22292d2691f93aa7b6770f5c250a33db3cc0
ToppCellASK452-Endothelial-Lymphatic|Endothelial / Donor, Lineage and Cell class of Lung cells from Dropseq

SLC12A6 RANBP10 OSGEP SLC38A1 PIEZO2 MLH1

1.49e-05195120620f492299a684ac1b7dd1bbc36a533cd6f9a1c93
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TCN2 CUBN SLC22A12 EEF2 SLC22A8 ASS1

1.53e-0519612063cf73ed99f3efa76b632c16a8b98b6b7758ff63f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CUBN SLC22A12 EEF2 SLC22A8 ASS1 AGXT

1.58e-051971206291458becbf90e9dda22ea069df7f9a45d827bcd
ToppCellCOVID-19-kidney-PCT-S3-1|COVID-19 / Disease (COVID-19 only), tissue and cell type

CUBN SLC22A7 SLC22A12 EEF2 SLC22A8 ASS1

1.62e-05198120636a60397f49f5381ae377155b73e1891448846b7
ToppCellNS-control-d_0-4-Epithelial-Secretory|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CP CPD CHD3 SLC38A1 ASS1 SLC16A7

1.67e-05199120632bdfff40fd442b88489c8b0f79af3927a51a03c
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-myeloid|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TCN2 CHIT1 ACSL1 TGFBI RGL1 CPVL

1.67e-05199120680ed217d28ba1c07facd0e103c25a02658dd848d
ToppCellcontrol-Epithelial-Secretory|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CP CPD CHD3 SLC38A1 ASS1 SLC16A7

1.67e-0519912063d01f90ffd271ca00129192787e4921bdca7e01e
ToppCellCOVID-19-Myeloid|COVID-19 / Condition, Lineage and Cell class

TCN2 ACSL1 TGFBI RGL1 GCA CPVL

1.72e-0520012064c9e936b5e100c1a3ef10ea262febccf8226df9f
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte-Astrocyte|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PAPLN PTGDS DNAH7 RGL1 HSD17B6 KCNN3

1.72e-052001206d0812817ef99608994193787a62d39adeb2070ca
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PAPLN PTGDS DNAH7 RGL1 HSD17B6 KCNN3

1.72e-052001206cd54ddf1919c98e84b7e4aba85b374fc8b407206
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW12-Mesenchymal|GW12 / Sample Type, Dataset, Time_group, and Cell type.

DNAH2 PEX11A PTGDS DNAH7 TGFBI MOCOS

1.72e-052001206be83f442179ba4217d12f0458059586ff3130991
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Tac2_Tacstd2|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TMTC2 GRIK3 FAT1 ASS1 SLC17A8

4.30e-05143120524fd24846fbef049af669a57d42fcc18928d2b27
ToppCelldroplet-Liver-nan-3m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLCO1B3 CP ACSL1 ASS1 AGXT

5.57e-0515112057758cfbe8dca849c90bd6e8bc63310e53beeb8fd
ToppCelldroplet-Liver-nan-3m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLCO1B3 CP ACSL1 ASS1 AGXT

5.57e-051511205b4a0546c1573b4b2290890307f2a5daf3a7cbb37
ToppCelldroplet-Liver-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLCO1B3 CP ACSL1 ASS1 AGXT

5.74e-0515212051febeeb7376e34b9f86c81b2cb1314ee12408864
ToppCelldroplet-Liver-nan-3m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLCO1B3 CP ACSL1 ASS1 AGXT

5.74e-051521205faa92f7c5a6db9f1eb7d8ec930ba7c8ed9fd1bf1
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-pDCs|Myeloid_cells / Location, Cell class and cell subclass

PAPLN GRIN1 SLC38A1 SLC35F3 SLC20A1

6.50e-05156120519472ef1642c2ad333aa3ce3675a25c6ab1d4556
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Macrophage-macrophage,_alveolar-Macro_c2-CCL3L1|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TCN2 ABHD12B TMTC2 RGL1 CPVL

6.70e-051571205a98d06cef80bfe8481b0940abce2b29675e45812
ToppCelldroplet-Liver-nan-3m-Epithelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLCO1B3 CP ACSL1 ASS1 AGXT

6.70e-051571205b72c6a1ed17bfc32d9dec193d934ea82e80b6bd5
ToppCelldroplet-Liver-Hepatocytes-18m-Epithelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLCO1B3 CP SLC22A7 ASS1 AGXT

7.54e-051611205274838cebdc7af1db32d309dfe42ef7ccd3c190b
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MBOAT1 TMTC2 SLC38A1 KLHL3 MOCOS

8.23e-0516412056fb2136168f430babfeb81ca7e151ca7a8092ec4
ToppCell367C-Myeloid-Macrophage-FABP4+_Macrophage_3|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

CYP26B1 CYP46A1 GFRA1 KLHL3 SLC25A23

8.71e-051661205f416d8a322f086c769659a9fab6b460a2d546ab1
ToppCellfacs-Heart-RV-24m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CP SLC22A7 GFRA1 GGT5 HSD17B6

8.96e-0516712053e3d8f6df2feefafad5b44ba0ebf5b5a0fe4ed58
ToppCellfacs-Heart-RV-24m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CP SLC22A7 GFRA1 GGT5 HSD17B6

8.96e-0516712053ad9f3122dbe96580f640388ef920ea209fc2349
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CUBN SLC22A7 SLC22A12 SLC22A8 ASS1

9.22e-051681205fa0d251693935116adf633d02b7ec4a295100865
ToppCelldroplet-Marrow-nan-24m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KALRN DNAH2 CPD ACAD10 FHIP1B

9.22e-051681205e979a4fbeb9f21048b47d69e6da75c57650697f2
ToppCellfrontal_cortex-Non-neuronal-leptomeningeal_cell|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TCN2 CP PTGDS GGT5 SLC22A8

1.00e-0417112052e43fb129ee9bdc3b31febc43c10f959bf0f4a7d
ToppCellmetastatic_Lymph_Node-Myeloid_cells-pDCs|metastatic_Lymph_Node / Location, Cell class and cell subclass

PAPLN PTGDS CYP46A1 SLC35F3 SLC20A1

1.00e-0417112051f8e66073088fc1969782e443bf00f8c1877ea91
ToppCellfrontal_cortex-Non-neuronal-leptomeningeal_cell-VLMC|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TCN2 CP PTGDS GGT5 SLC22A8

1.00e-041711205e219a1aa59a96e4bc3e2eacf985679174a51de41
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA8 GFRA1 GGT5 PIEZO2 HSD17B6

1.03e-0417212051ef243bce63d841c25e4b74d029d1377f84bcc3d
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA8 GFRA1 GGT5 PIEZO2 HSD17B6

1.03e-041721205ab1c81be29f93ca8920c6ab5ab92f497a9256d3f
ToppCell5'-Adult-Distal_Rectal-Hematopoietic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PCDHGB2 ACSL1 RGL1 CPVL SLC16A7

1.06e-041731205b335ca2a247156eba821943b2b9fc9922230b409
ToppCellControl-Myeloid-MoAM2,_CCL18|Control / Condition, Lineage and Cell class

NOX5 SLC46A1 CHIT1 TGFBI RGL1

1.09e-0417412054c64ff5666812fb4efa440ba4faeca51d916d68e
ToppCell356C-Myeloid-Macrophage-SPP1+_Macrophage_4|356C / Donor, Lineage, Cell class and subclass (all cells)

SLC46A1 TGFBI RGL1 PIEZO2 CPVL

1.09e-04174120575b3a852140fb726025c3c987143d67944afde2d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EML6 DNAH7 SLC35F3 CPVL DNAH11

1.12e-041751205284fdc7a9d303636a637041846850d19d114861a
ToppCellB_cells-pDCs|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis

PTGDS CYP46A1 TGFBI SLC35F3 SLC20A1

1.15e-041761205ce757de9e09a225f3f96433f103f43619b0e0dda
ToppCellnormal_Lymph_Node-B_lymphocytes-GrB-secreting_B_cells|B_lymphocytes / Location, Cell class and cell subclass

PTGDS CYP46A1 TGFBI SLC35F3 SLC20A1

1.15e-041761205d6e660df92a3d7dd5732171ee623763faf108476
ToppCellCOVID-19-kidney-PCT-S3-2|COVID-19 / Disease (COVID-19 only), tissue and cell type

SLCO1B3 CP SLC22A7 HSD17B6 AGXT

1.15e-041761205b6497324e3e52f514ce556a3fa0c3011c45dcc7b
ToppCellControl-Myeloid-MoAM2,_CCL18|Myeloid / Condition, Lineage and Cell class

NOX5 SLC46A1 CHIT1 TGFBI RGL1

1.18e-041771205470f54fe2b21c7350ea471e02039461a3808f700
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC12A6 CUBN SLC22A7 SLC22A12 AGXT

1.18e-0417712052f81b26be89cc2fd8eafadaf7eae3c6ad6521462
ToppCellfacs-Marrow-B-cells-18m-Hematologic-hematopoietic_stem_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EML6 TEX14 CYP46A1 SLC35F3 CACNA1H

1.18e-04177120535d42b07d9c31528bf59199e361bb8a3bfbe3b75
ToppCellfacs-Kidney-nan-18m|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CP CUBN SLC22A7 SLC22A8 ASS1

1.18e-041771205d4cd54c07f1e51b5485270348fb7195d53465027
ToppCellprimary_visual_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Osr1_Mc5r|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CYP26B1 TCN2 CP PTGDS SLC22A8

1.18e-041771205599cf7f5b774e197a1b43c98e4b9a8c1a618f38a
ToppCellfacs-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KALRN CUBN PTGDS KCNN3 SLC12A7

1.18e-041771205d68132e145bd413404fdbe215b5dbe520e756e50
ToppCellMid-temporal_gyrus_(MTG)|World / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CHD3 SLC22A8 SLC35F3 KCNN3 SYN2

1.21e-041781205ad187db4c40b9078d54dd915c143e0172b2f47b8
ToppCellCOVID-19-kidney-Epi_(Mes)|COVID-19 / Disease (COVID-19 only), tissue and cell type

PAPLN GRM5 DNAH7 GFRA1 FAT1

1.21e-041781205544379f5a6145429762258d426b876bb36c112f5
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KALRN GGT5 KLHL3 PIEZO2 KCNN3

1.21e-041781205ad3de3e03a401dac64431a541899445262246347
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NOX5 DNAH2 DNAH7 KCNN3 DNAH11

1.24e-0417912055e5f1cdf4aa66868d45b74ba91e20e848a3cbaff
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CUBN SLC22A12 ACSL1 SLC22A8 ASS1

1.24e-04179120578fae47ec9bff4e0159a86a281e831d7f8ee925a
ToppCelldroplet-Kidney-nan-21m-Epithelial-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCN2 SLC22A7 ACSL1 SLC22A8 ASS1

1.27e-0418012052b2c656d6620afa32555f14aad94ac56e71e360c
ToppCelldroplet-Kidney|droplet / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCN2 CUBN SLC22A12 SLC22A8 ASS1

1.27e-0418012057e5f497699876ac8e1ce780626c6f5a1f6f5f079
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MBOAT1 EML6 TMTC2 SLC38A1 MOCOS

1.27e-041801205023ec0b080c8a5cd0f36e83c6b17d4be3c01edb5
ToppCellfacs-Marrow-B-cells-18m-Hematologic-MPP_Fraction_B_+_C|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KALRN SLC46A1 POGZ CYP46A1 SLC12A7

1.27e-0418012057368ab31c3273374ef260f0d710d4eea83cbc4a2
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MBOAT1 EML6 TMTC2 KLHL3 MOCOS

1.27e-041801205788d5fbf688365b5d92d3aa19b9f8e9448f8be5a
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KALRN GGT5 KLHL3 PIEZO2 KCNN3

1.31e-041811205e898ecb8d8f2eb2204225b7b0d665cadcd241139
ToppCellCOVID-19-kidney-Stressed_PCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

CUBN SLC22A7 SLC22A12 SLC22A8 SYN2

1.31e-0418112056980ea624151da32b7f537f263e40fcb87a02e81
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CUBN SLC22A7 SLC22A12 SLC22A8 ASS1

1.34e-041821205e1e58176f533092b6b974ca1ce8b02192a6e193d
ToppCellfacs-Liver-Hepatocytes-24m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACAD10 GFRA1 SLC20A2 SLC17A8 SLC25A23

1.34e-041821205770ce9f3f4538d0181a0181543841bc964c68274
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GRM5 FAT1 SLC35F3 CPVL DNAH11

1.34e-0418212055e1b316599436740f1b30875f0ebd33c3edfb2b6
ToppCellmetastatic_Lymph_Node-Myeloid_cells-pDCs|Myeloid_cells / Location, Cell class and cell subclass

PTGDS CYP46A1 SLC38A1 SLC35F3 SLC20A1

1.34e-04182120502e04294fce12591c32d7bd0e866a000ad1f836e
ToppCelldroplet-Kidney-nan-21m-Epithelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCN2 CUBN SLC22A7 ACSL1 SLC22A8

1.34e-041821205942c18a27b22fb33a5200d5717cad972f3ef0576
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MBOAT1 EML6 TMTC2 KLHL3 MOCOS

1.34e-041821205f96095b81188b52db8fcfca4837129cfcd9bd7b7
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CUBN SLC22A7 SLC22A12 SLC22A8 ASS1

1.34e-04182120557bb5a2da976464ba7c4460106bd9f692008ebd9
ToppCellfacs-Liver-Hepatocytes-24m-Epithelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACAD10 GFRA1 SLC20A2 SLC17A8 SLC25A23

1.34e-04182120577ab860e2add49dad0c1ffbfc64278ad499dfbd5
Drugtrichostatin A; Up 200; 0.1uM; MCF7; HG-U133A

RANBP10 CYP26B1 STK17A PTGDS CYP46A1 RGL1 PIEZO2 AGXT NUP93

7.13e-071901199331_UP
DrugAdenosine 5'-monophosphate monohydrate [18422-05-4]; Up 200; 11uM; PC3; HT_HG-U133A

CYP26B1 STK17A PGAP6 DNAH7 TGFBI BNC1 LIPG HSD17B6 SLC25A23

8.13e-0719311996760_UP
DrugBumetanide

SLC12A6 SLC22A7 SLC22A8 SLC12A7

1.23e-06161194ctd:D002034
Drugsodium

SLC12A6 PRKD2 NOX5 GART SLCO1B3 CP SLC46A1 GRIK3 SLC38A1 SLC22A8 SLC20A1 SLC20A2 AGXT MLH1 KCNN3 SLC17A8 CACNA1H SLC26A11

1.99e-0694411918CID000000923
Drugprobenecid

SLCO1B3 SLC46A1 SLC22A7 SLC22A12 GGT5 SLC22A8 SLC16A7

3.84e-061231197CID000004911
DrugSulfobromophthalein

SLCO1B3 SLC46A1 SLC22A7 SLC22A8

1.13e-05271194ctd:D013448
Drugtelmisartan

NOX5 SLCO1B3 ACSL1 TGFBI SLC22A8 SLC33A1

1.13e-05961196CID000065999
DrugDehydroepiandrosterone Sulfate

SLCO1B3 SLC22A7 SLC22A12 SLC22A8

1.52e-05291194ctd:D019314
Drugp-Aminohippuric Acid

SLC22A7 SLC22A12 SLC22A8

1.63e-05101193ctd:D010130
Drugsulfobromophthalein

SLCO1B3 SLC46A1 SLC22A7 GGT5 SLC22A8 ABCE1

1.70e-051031196CID000005345
Drugpheophytin

PRKD2 TCN2 NOX5 SLCO1B3 CP PTGDS DHX9 GGT5 ACSL1

1.88e-052841199CID000000250
Drugethylnylestradiol

RAF1 PRKD2 CYP26B1 TCN2 BCAS3 HMBS CP CPD CYP46A1 GGT5 TGFBI ARSL LIPG SLC20A1 SLC20A2 HSD17B6 KCNN3 CACNA1H MOCOS

2.59e-05125111919CID000003285
DrugNL14

HSD17B6 MLH1

2.71e-0521192CID011847435
Diseasemental development measurement

PCDHGB2 PCDHGA10 PCDHGA5 PCDHGA1

2.69e-06251164EFO_0008230
Diseasechildhood trauma measurement, alcohol consumption measurement

PCDHGB2 PCDHGA10 PCDHGA5 PCDHGA1 HERC3

9.11e-06711165EFO_0007878, EFO_0007979
Diseasegout

PRKD2 BCAS3 ACAD10 CXXC1 SLC22A12 SLC38A1 FAT1

1.30e-051961167EFO_0004274
Diseasepancreatic carcinoma (biomarker_via_orthology)

RAF1 CHD3

4.58e-0531162DOID:4905 (biomarker_via_orthology)
Diseaserenal agenesis (is_implicated_in)

ITGA8 GFRA1

9.15e-0541162DOID:14766 (is_implicated_in)
DiseaseSarcosine measurement

PCDHGB2 PCDHGA5 PCDHGA1

9.90e-05231163EFO_0021668
DiseasePancytopenia

TCN2 SLC46A1 MOCOS

1.44e-04261163C0030312
DiseaseAnemia, Megaloblastic

TCN2 CUBN

1.52e-0451162C0002888
Diseasebilirubin metabolic disorder (implicated_via_orthology)

SLCO1B3 SLCO1B7

1.52e-0451162DOID:2741 (implicated_via_orthology)
Diseasewhole-brain volume

CUBN DNAH11

1.52e-0451162EFO_0005089
Diseasecerebral infarction (is_implicated_in)

KALRN GRIN1 LIPG

2.01e-04291163DOID:3526 (is_implicated_in)
DiseaseInvoluntary Movements

CP GRIN1

3.18e-0471162C0427086
DiseaseAllodynia

RAF1 GRIN1 SYN2 CACNA1H

3.43e-04841164C0458247
DiseaseMechanical Allodynia

RAF1 GRIN1 SYN2 CACNA1H

3.43e-04841164C2936719
DiseaseHyperalgesia, Secondary

RAF1 GRIN1 SYN2 CACNA1H

3.43e-04841164C0751212
DiseaseHyperalgesia, Primary

RAF1 GRIN1 SYN2 CACNA1H

3.43e-04841164C0751211
DiseaseHyperalgesia, Thermal

RAF1 GRIN1 SYN2 CACNA1H

3.43e-04841164C0751214
DiseaseTactile Allodynia

RAF1 GRIN1 SYN2 CACNA1H

3.43e-04841164C0751213
DiseaseDrug toxicity

TCN2 CP CACNA1H MOCOS

3.43e-04841164C0013221
DiseaseAdverse reaction to drug

TCN2 CP CACNA1H MOCOS

3.43e-04841164C0041755
DiseaseHyperalgesia

RAF1 GRIN1 SYN2 CACNA1H

3.43e-04841164C0020429
Diseasebilirubin measurement

BCAS3 SLCO1B3 CHD3 MFSD4B PGAP6 SLCO1B7 SYN2 DNAH11

3.69e-044421168EFO_0004570
DiseaseDystonia

TREX1 CP SLC46A1 SLC20A2

3.76e-04861164C0013421
Diseasemean corpuscular hemoglobin concentration

RMND5A CYP26B1 KALRN PCDHGA5 STK17A ACAD10 PGAP6 SLC38A1 SLC20A2 HSD17B6 SYN2 DHX32 SLC12A7

4.12e-04110511613EFO_0004528
Diseaseepilepsy (implicated_via_orthology)

SLC12A6 KALRN DHX9 SYN2 SLC12A7

4.74e-041631165DOID:1826 (implicated_via_orthology)
Diseasehexadecenedioate (C16:1-DC) measurement

SLCO1B3 SLCO1B7

5.42e-0491162EFO_0800562
Diseasesciatic neuropathy (biomarker_via_orthology)

GRIN1 GFRA1 SLC17A8 CACNA1H

6.40e-04991164DOID:11446 (biomarker_via_orthology)
Diseasehematocrit

RANBP10 KALRN BCAS3 DNAH2 CHD3 PGAP6 KLHL3 VAC14 FAT1 SLC20A2 SYN2 TASOR

6.42e-04101111612EFO_0004348
DiseaseWNT1-inducible-signaling pathway protein 1 measurement

SLC46A1 SEPSECS

6.75e-04101162EFO_0008321
DiseaseGastric Adenocarcinoma

PRKD2 TEX14 MLH1

7.45e-04451163C0278701
Diseaseurate measurement

PRKD2 BCAS3 SLC25A30 CHD3 TEX14 CUBN CXXC1 SLC22A7 SLC22A12 SLC20A2 HERC3

8.19e-0489511611EFO_0004531
Diseaseglycochenodeoxycholate glucuronide (1) measurement

SLCO1B3 SLCO1B7

1.16e-03131162EFO_0800474
Diseasefree cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement

HMBS SPG11 LIPG SYN2 NUP93 DNAH11

1.29e-033031166EFO_0004612, EFO_0020945
Diseasefree cholesterol to total lipids in very large HDL percentage

LIPG SYN2 NUP93

1.34e-03551163EFO_0022288
Diseaseplatelet measurement

KALRN EML6 ACAD10 SYN2 SLC12A7 TASOR

1.57e-033151166EFO_0005036
Diseasecholesteryl esters to total lipids in large HDL percentage

SLC38A1 SYN2 NUP93

1.64e-03591163EFO_0022248
DiseaseNeuralgia, Supraorbital

GRM5 GFRA1

1.77e-03161162C0038870
DiseaseNeuralgia

GRM5 GFRA1

1.77e-03161162C0027796
DiseaseNeuralgia, Atypical

GRM5 GFRA1

1.77e-03161162C0234247
DiseaseNeuralgia, Stump

GRM5 GFRA1

1.77e-03161162C0234249
DiseaseNeuralgia, Iliohypogastric Nerve

GRM5 GFRA1

1.77e-03161162C0423712
DiseaseNeuralgia, Perineal

GRM5 GFRA1

1.77e-03161162C0423711
DiseaseParoxysmal Nerve Pain

GRM5 GFRA1

1.77e-03161162C0751373
DiseaseNerve Pain

GRM5 GFRA1

1.77e-03161162C0751372
DiseaseNeuralgia, Ilioinguinal

GRM5 GFRA1

1.77e-03161162C0751371
DiseaseNeuralgia, Vidian

GRM5 GFRA1

1.77e-03161162C0042656
Diseaselymphocyte count

RANBP10 RMND5A MBOAT1 KALRN PCDHGB2 PCDHGA10 BCAS3 PCDHGA5 PCDHGA1 EML6 ACAD10 GGT5 BNC1 SYN2

1.84e-03146411614EFO_0004587
DiseaseColorectal Carcinoma

TCN2 KALRN SLCO1B3 GRIK3 CUBN FAT1 ABCE1 MLH1 SLC33A1

1.85e-037021169C0009402
DiseaseIntellectual Disability

TREX1 TCN2 CHD3 POGZ GRIN1 OSGEP ASS1

1.98e-034471167C3714756
Diseasepartial epilepsy

ASS1 SLC33A1

2.00e-03171162EFO_0004263
DiseaseX-21441 measurement

SLCO1B3 SLCO1B7

2.00e-03171162EFO_0800814
Diseasemean platelet volume

SLC12A6 KALRN PCDHGB2 PCDHGA10 PCDHGA5 PCDHGA1 EML6 ACSL1 SLC12A7 STK38L TASOR

2.31e-03102011611EFO_0004584
Diseaseschizophrenia (implicated_via_orthology)

GRIN1 GRM5 TAAR1

2.46e-03681163DOID:5419 (implicated_via_orthology)
Diseasestroke

KALRN CHD3 SLC22A7 TGFBI

2.55e-031441164EFO_0000712
DiseaseSchizophrenia

ITGA8 AMBRA1 CP GRIK3 GRM5 GFRA1 PITPNM1 KCNN3 SYN2 TAAR1

2.57e-0388311610C0036341
Diseaseneurodegenerative disease (implicated_via_orthology)

GRIK3 GRIN1 SLC17A8 TOLLIP

2.62e-031451164DOID:1289 (implicated_via_orthology)
Diseaseautism spectrum disorder (implicated_via_orthology)

POGZ GRIN1 SYN2 MOCOS

3.10e-031521164DOID:0060041 (implicated_via_orthology)
Diseaseserum gamma-glutamyl transferase measurement

KALRN SLCO1B3 SLC25A30 PGAP6 SLCO1B7 SLC38A1 MLH1 KCNN3 SLC17A8 SYN2

3.29e-0391411610EFO_0004532
Diseaseschizophrenia (is_implicated_in)

ITGA8 KCNN3 SYN2

3.63e-03781163DOID:5419 (is_implicated_in)
Diseasecholesterol in large HDL measurement

LIPG SYN2 NUP93

3.90e-03801163EFO_0021900

Protein segments in the cluster

PeptideGeneStartEntry
DPLIGGTYMTLLNTV

SLC33A1

441

O00400
GRYGTLFTMDRVLTP

TGFBI

486

Q15582
AFLTGRYPIRSGMVS

ARSH

61

Q5FYA8
AAFLTGRYPVRSGMV

ARSL

91

P51690
YVRTLPTNTLMGFGA

ACSL1

21

P33121
QAIGLMGYRLSPQTL

GCA

146

P28676
TVNFYLRVEPGVMLG

ABHD12B

96

Q7Z5M8
FKGTSRMGSLVYPIT

BNC1

821

Q01954
IFITMNPGYAGRTEL

DNAH11

1991

Q96DT5
TYRAVIFDMGGVLIP

ACAD10

41

Q6JQN1
GGETSMRRVFNVLYP

AMBRA1

986

Q9C0C7
MSNPFLGSYGVIILD

DHX32

171

Q7L7V1
MTLGTITKRTGPYLF

BCAS3

536

Q9H6U6
NRFIGMKSRGIYETP

ASS1

271

P00966
TLITFAGMIPYRTSG

NUP93

791

Q8N1F7
QIIFMVGRGYASPDL

RAF1

556

P04049
HYPNGVLGSMSTRIV

RANBP10

461

Q6VN20
GPMRLYVGSLHFNIT

RBM23

261

Q86U06
GVMQGTVPYLGTFLT

RGL1

411

Q9NZL6
TMGLSARYGPQFTLQ

PCDHGA5

871

Q9Y5G8
IGITPFASILQSIMY

NOX5

591

Q96PH1
AMLYGTGPVSSILVT

SLC16A8

66

O95907
GTYQTLEMFPRTPGI

CP

1021

P00450
ILGMPTYGRSFTLAS

CHIT1

261

Q13231
PIYTLIIQGTNMAGL

FAT1

1731

Q14517
LLMALSAGSPTVGRY

FHIP1B

236

Q8N612
GDTLMGITYTVLTPF

OR10H5

271

Q8NGA6
FATITPLMFTGYGLL

SLC46A1

351

Q96NT5
LQRIGIGLSPAMSYS

GRM5

646

P41594
LLFLTGSDRIPIYGM

HERC3

981

Q15034
PISIRQMAYVSGLSF

APH1A

111

Q96BI3
VMRLFTPISGGYRTV

CYP26B1

361

Q9NR63
LSMLYIDNPVGTGFS

CPVL

146

Q9H3G5
TGYLSTMVGLILGPF

PCMTD1

91

Q96MG8
TGYLSSMVGLILGPF

PCMTD2

91

Q9NV79
ISITFLSIGYGDMVP

KCNN3

501

Q9UGI6
TMGLSARYGPQFTLQ

PCDHGA10

876

Q9Y5H3
TMGLSARYGPQFTLQ

PCDHGB2

871

Q9Y5G2
IGVLTYVMLSGVSPF

KALRN

2866

O60229
LAVMYAGGPVSSVLV

SLC16A7

66

O60669
SVGVIMYVSLSGTFP

PRKD2

736

Q9BZL6
TYTRSFGLSIGIQMP

LIPG

221

Q9Y5X9
PTGSVRISFGYMSTL

MOCOS

461

Q96EN8
LPGVSMASVGIAIYT

PGAP6

696

Q9HCN3
MGRLITGATSPTVLY

OSGEP

116

Q9NPF4
PMVSGTNYSLGLRFA

ITGA8

731

P53708
LLGPYLVFMASTING

NAT10

401

Q9H0A0
GISMSATTVGLYLVP

MFSD4B

66

Q5TF39
GVHIIRGYSVMSTPF

CUBN

2981

O60494
YGVVTMPFSVREGIN

ABCE1

296

P61221
GSMYPTRIEGATRLF

CXXC1

516

Q9P0U4
GIAPAMLRQASYGTI

SLC25A30

71

Q5SVS4
ISIVEPGYFRTGMTN

HSD17B6

201

O14756
PGNTPLLFSTYVMGR

CYP46A1

386

Q9Y6A2
LLAYSGLIGTVMTPN

GFRA1

286

P56159
SLYPRSGTGQTIKMQ

DNAJB14

276

Q8TBM8
PRFITATGGTLHMYQ

CHD3

726

Q12873
VFITMNPGYAGRSEL

DNAH7

1426

Q8WXX0
GTYNLTVVLTGYMPL

CPD

426

O75976
LSVALDGGSMLVTYP

CPD

1091

O75976
FGAMVYSPRTGIILN

GGT5

411

P36269
YGILTTDFSGPLMIV

MBOAT1

131

Q6ZNC8
LLPTNMSTGRSYAGV

KLHL3

566

Q9UH77
VSTGLKVRIMGPNYT

EEF2

421

P13639
GPVFTMYTTLRDGLI

EML6

1596

Q6ZMW3
TQVGLGISTLLMYVP

COX15

366

Q7KZN9
YPGLQFEIIAMSTTG

HMBS

46

P08397
MTLGVSILYRKPNGT

GRIK3

536

Q13003
SLRLATGLGTMNYPT

CACNA1H

601

O95180
IFITMNPGYAGRTEL

DNAH2

1901

Q9P225
LYPTVLRQTGMGLTA

SLC22A7

456

Q9Y694
LYPTVIRQTGMGVSN

SLC22A8

436

Q8TCC7
PMAQSIYLAGILVGA

SLC22A12

146

Q96S37
VVPAGGSYFMISRAL

SLC12A6

246

Q9UHW9
TLLVGIYFPSVTGIM

SLC12A7

421

Q9Y666
VGINLFSIMYTGAPL

SLC20A1

206

Q8WUM9
FSIMYTGAPVLGLVL

SLC20A2

196

Q08357
PSAAGINLMIGSTRY

DHX9

1141

Q08211
GDTLMGITYTVLTPF

OR10H1

271

Q9Y4A9
TMGLSARYGPQFTLQ

PCDHGA1

871

Q9Y5H4
DMPLYILSSSQGRGL

SMG8

886

Q8ND04
LIIGMQYAGLPSINS

SYN2

201

Q92777
IQLAGRVMLPYSSGI

VAC14

286

Q08AM6
LVDSVASLGGTPLYM

AGXT

181

P21549
RLYFISLLMGGTTNQ

RMND5A

196

Q9H871
FEGLTQRGSIPTYMK

STK38L

446

Q9Y2H1
LTGATQMAYLGSLPV

TEX14

221

Q8IWB6
DGTVLPTLVFYRGQM

POGZ

1166

Q7Z3K3
TRTMLLQPAGSLGSY

PTGDS

91

P41222
RDGPFVYGRTQMTLT

TFB1M

161

Q8WVM0
GLVSSIAGMITVAYP

PEX11A

226

O75192
IMRSLGGILVPIYFG

SLCO1B7

531

G3V0H7
GSTFRDLLPGEYVQM

SKIV2L

686

Q15477
RMYFTQTLLPGLAGP

MLH1

341

P40692
MGTSVTGLYPELFTL

MROH2B

1151

Q7Z745
LGYSTTVGPKMLVNF

OR8K3

71

Q8NH51
FGIAVTYPTLMSLGI

SLC35F3

321

Q8IY50
VLTYVMLTGISPFLG

STK17A

251

Q9UEE5
GNVYSTPLALQFLMT

TCN2

241

P20062
ITILGSPSMGVYLSR

TASOR

206

Q9UK61
TLLALATTMYSPGGV

SPG11

1081

Q96JI7
SGRFMYGPLDVVTLT

PITPNM1

936

O00562
GSYLPLVVFLVSSGM

TAS2R5

176

Q9NYW4
RGYNQILIVPMGATS

PAPLN

196

O95428
GLTNMLGSLVSSYPV

SLC26A11

346

Q86WA9
GFVIAERVLYIPSMG

TMTC2

416

Q8N394
SMVIRTLGGILAPIY

SLCO1B3

576

Q9NPD5
MATTVSTQRGPVYIG

TOLLIP

1

Q9H0E2
VTITLGGYQPIFTMS

PIEZO2

2441

Q9H5I5
GVLTFMTSFYIPGSI

TAAR1

191

Q96RJ0
PTSMIGVGLFTNLVY

TEX261

66

Q6UWH6
RMGQLFSDYVGSPIT

WDR83

181

Q9BRX9
GTPYTGILYAGIMLT

GART

266

P22102
TVIQSLTMYPRLGGF

SYMPK

1001

Q92797
GSLAGATAQTIIYPM

SLC25A23

286

Q9BV35
VPLGSMQTVSGYTFR

SEPSECS

406

Q9HD40
FGTIRPMYGVTASAR

TREX1

226

Q9NSU2
YIPGTTSLGMSVFNL

SLC38A1

66

Q9H2H9
LTPGYFRVLQMQVAG

ZNF593OS

6

A0A0U1RRA0
IAPRYASILMGISNG

SLC17A8

441

Q8NDX2
TGGYTRMLQIPNRSL

MRPL17

101

Q9NRX2
AGFYRIPVLGLTTRM

GRIN1

111

Q05586