Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionaspartic-type endopeptidase activity

ERVK-6 ERVK-8 ERVK-18 ERVK-7 ERVK-25 ERVK-10

1.28e-0837886GO:0004190
GeneOntologyMolecularFunctionaspartic-type peptidase activity

ERVK-6 ERVK-8 ERVK-18 ERVK-7 ERVK-25 ERVK-10

1.52e-0838886GO:0070001
GeneOntologyMolecularFunctionRNA-DNA hybrid ribonuclease activity

ERVK-6 ERVK-8 ERVK-7 ERVK-10

1.13e-0711884GO:0004523
GeneOntologyMolecularFunctionRNA-directed DNA polymerase activity

ERVK-6 ERVK-8 ERVK-7 ERVK-10

3.41e-0714884GO:0003964
GeneOntologyMolecularFunctionRNA stem-loop binding

ERVK-6 ERVK-8 ERVK-7 ERVK-10

1.99e-0621884GO:0035613
GeneOntologyMolecularFunctiondolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity

ALG10 ALG10B

1.92e-052882GO:0106073
GeneOntologyMolecularFunctionendopeptidase activity

ERVK-6 ERAP2 GZMK ERVK-8 ERVK-18 ERVK-7 ERVK-25 ERVK-10 USP1 CTSZ

1.95e-054308810GO:0004175
GeneOntologyMolecularFunctionRNA endonuclease activity, producing 5'-phosphomonoesters

ERVK-6 ERVK-8 ERVK-7 ERVK-10

2.08e-0537884GO:0016891
GeneOntologyMolecularFunctionDNA polymerase activity

ERVK-6 ERVK-8 ERVK-7 ERVK-10

2.32e-0538884GO:0034061
GeneOntologyMolecularFunctionendonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters

ERVK-6 ERVK-8 ERVK-7 ERVK-10

4.99e-0546884GO:0016893
GeneOntologyMolecularFunctionpeptidase activity

ERVK-6 ERAP2 GZMK ERVK-8 ERVK-18 ERVK-7 ERVK-25 ERVK-10 AGBL2 USP1 CTSZ

1.39e-046548811GO:0008233
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity

SCN11A SCN5A SCN10A

2.00e-0426883GO:0005248
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity involved in cardiac muscle cell action potential

SCN5A SCN10A

2.85e-046882GO:0086006
GeneOntologyMolecularFunctionRNA endonuclease activity

ERVK-6 ERVK-8 ERVK-7 ERVK-10

4.11e-0479884GO:0004521
GeneOntologyMolecularFunctionU3 snoRNA binding

PRKDC TBL3

1.03e-0311882GO:0034511
GeneOntologyMolecularFunctioncatalytic activity, acting on DNA

ERVK-6 ERVK-8 ERVK-7 ERVK-10 DNMT3L DHX30

1.06e-03262886GO:0140097
GeneOntologyMolecularFunctionsodium channel activity

SCN11A SCN5A SCN10A

1.56e-0352883GO:0005272
GeneOntologyBiologicalProcessDNA integration

ERVK-6 ERVK-8 ERVK-7 ERVK-10

2.05e-0713874GO:0015074
GeneOntologyBiologicalProcessDNA synthesis involved in DNA repair

ERVK-6 ERVK-8 ERVK-7 ERVK-10 USP1

1.76e-0648875GO:0000731
GeneOntologyBiologicalProcessRNA-templated DNA biosynthetic process

ERVK-6 ERVK-8 ERVK-7 ERVK-10 MAPK3

2.66e-0583875GO:0006278
GeneOntologyCellularComponentvoltage-gated sodium channel complex

SCN11A SCN5A SCN10A

4.86e-0517893GO:0001518
GeneOntologyCellularComponentC-fiber

SCN11A SCN10A

1.07e-044892GO:0044299
GeneOntologyCellularComponentsodium channel complex

SCN11A SCN5A SCN10A

2.52e-0429893GO:0034706
HumanPhenoElevated circulating amyloid A concentration

MEFV IL6ST

2.31e-052252HP:0033332
DomainNa_channel_asu

SCN11A SCN5A SCN10A

9.23e-0610813IPR001696
DomainNa_trans_assoc

SCN11A SCN5A SCN10A

9.23e-0610813IPR010526
DomainNa_trans_assoc

SCN11A SCN5A SCN10A

9.23e-0610813PF06512
DomainAlg10

ALG10 ALG10B

1.86e-052812IPR016900
DomainDIE2_ALG10

ALG10 ALG10B

1.86e-052812PF04922
DomainChannel_four-helix_dom

SCN11A CATSPER2 SCN5A SCN10A

1.09e-0457814IPR027359
Domain-

SCN11A CATSPER2 SCN5A SCN10A

1.09e-04578141.20.120.350
DomainIon_trans_dom

SCN11A CATSPER2 SCN5A SCN10A

1.53e-03114814IPR005821
DomainIon_trans

SCN11A CATSPER2 SCN5A SCN10A

1.53e-03114814PF00520
DomainPI3/4_kinase_CS

PIK3CB PRKDC

1.88e-0315812IPR018936
Domain-

PIK3CB PRKDC

2.14e-03168121.10.1070.11
DomainPI3Kc

PIK3CB PRKDC

2.14e-0316812SM00146
DomainGal_Oxase/kelch_b-propeller

KBTBD6 KBTBD7 TBL3

2.14e-0359813IPR011043
DomainNAD/diacylglycerol_kinase

NADK DGKE

2.42e-0317812IPR016064
DomainPI3/4_kinase_cat_dom

PIK3CB PRKDC

2.72e-0318812IPR000403
DomainPI3_PI4_kinase

PIK3CB PRKDC

2.72e-0318812PF00454
DomainPI3_4_KINASE_3

PIK3CB PRKDC

2.72e-0318812PS50290
DomainPI3_4_KINASE_1

PIK3CB PRKDC

2.72e-0318812PS00915
DomainPI3_4_KINASE_2

PIK3CB PRKDC

2.72e-0318812PS00916
Domain-

WDR38 STRN3 CORO2A BBS7 NUP133 TBL3

3.25e-033338162.130.10.10
DomainWD40/YVTN_repeat-like_dom

WDR38 STRN3 CORO2A BBS7 NUP133 TBL3

3.34e-03335816IPR015943
DomainCRAL_TRIO

KALRN ARHGAP8

3.70e-0321812PF00650
DomainDAPIN

NLRP14 MEFV

4.06e-0322812PS50824
DomainPYRIN

NLRP14 MEFV

4.06e-0322812PF02758
DomainDAPIN

NLRP14 MEFV

4.06e-0322812IPR004020
DomainPYRIN

NLRP14 MEFV

4.06e-0322812SM01289
DomainTPR-contain_dom

CEP70 ODAD4 PRKDC UNC45A

4.12e-03150814IPR013026
Domain-

KALRN ARHGAP8

4.43e-03238123.40.525.10
DomainSEC14

KALRN ARHGAP8

5.22e-0325812SM00516
DomainWD40_repeat_CS

WDR38 STRN3 CORO2A TBL3

5.64e-03164814IPR019775
DomainTPR_REGION

CEP70 ODAD4 PRKDC UNC45A

5.77e-03165814PS50293
DomainTPR

CEP70 ODAD4 PRKDC UNC45A

5.77e-03165814PS50005
Pubmed

Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans.

ERVK-6 ERVK-7 ERVK-10

6.47e-08489310469592
Pubmed

A revised nomenclature for transcribed human endogenous retroviral loci.

ERVK-6 ERVK-8 ERVK-18 ERVK-7 ERVK-25 ERVK-10

1.61e-079489621542922
Pubmed

Quantitation of HERV-K env gene expression and splicing in human breast cancer.

ERVK-6 ERVK-18 ERVK-7

1.61e-07589312629516
Pubmed

International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels.

SCN11A SCN5A SCN10A

1.35e-06989316382098
Pubmed

Genome-wide association study of PR interval.

WNT11 SCN5A SCN10A

3.50e-061289320062060
Pubmed

The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.

KIF20A RAPGEF6 LMO7 SLC7A5 PRKDC UNC45A USP1

4.45e-0625689733397691
Pubmed

A common genetic variant within SCN10A modulates cardiac SCN5A expression.

SCN5A SCN10A

6.48e-06289224642470
Pubmed

Heat-resistant action potentials require TTX-resistant sodium channels NaV1.8 and NaV1.9.

SCN11A SCN10A

6.48e-06289229970412
Pubmed

Correlation of Nav1.8 and Nav1.9 sodium channel expression with neuropathic pain in human subjects with lingual nerve neuromas.

SCN11A SCN10A

6.48e-06289224144460
Pubmed

Novel isoforms of the sodium channels Nav1.8 and Nav1.5 are produced by a conserved mechanism in mouse and rat.

SCN5A SCN10A

6.48e-06289215047701
Pubmed

Sodium Channel Nav1.8 Underlies TTX-Resistant Axonal Action Potential Conduction in Somatosensory C-Fibers of Distal Cutaneous Nerves.

SCN11A SCN10A

6.48e-06289228450535
Pubmed

Maladaptive activation of Nav1.9 channels by nitric oxide causes triptan-induced medication overuse headache.

SCN11A SCN10A

6.48e-06289231534133
Pubmed

Mutations in SCN10A are responsible for a large fraction of cases of Brugada syndrome.

SCN5A SCN10A

6.48e-06289224998131
Pubmed

Specialized functions of Nav1.5 and Nav1.9 channels in electrogenesis of myenteric neurons in intact mouse ganglia.

SCN11A SCN5A

6.48e-06289224719102
Pubmed

From GWAS to function: genetic variation in sodium channel gene enhancer influences electrical patterning.

SCN5A SCN10A

6.48e-06289224360055
Pubmed

Single nucleotide polymorphisms of SCN5A and SCN10A genes increase the risk of ventricular arrhythmias during myocardial infarction.

SCN5A SCN10A

6.48e-06289232330377
Pubmed

Tetrodotoxin-resistant voltage-gated sodium channels Na(v)1.8 and Na(v)1.9 are expressed in the retina.

SCN11A SCN10A

6.48e-06289218399542
Pubmed

Comparable clinical characteristics in Brugada syndrome patients harboring SCN5A or novel SCN10A variants.

SCN5A SCN10A

6.48e-06289231292628
Pubmed

Exploring the role of nociceptor-specific sodium channels in pain transmission using Nav1.8 and Nav1.9 knockout mice.

SCN11A SCN10A

6.48e-06289219931571
Pubmed

Contributions of NaV1.8 and NaV1.9 to excitability in human induced pluripotent stem-cell derived somatosensory neurons.

SCN11A SCN10A

6.48e-06289234930944
Pubmed

Dissecting the role of sodium currents in visceral sensory neurons in a model of chronic hyperexcitability using Nav1.8 and Nav1.9 null mice.

SCN11A SCN10A

6.48e-06289216857712
Pubmed

The Nav1.9 channel is a key determinant of cold pain sensation and cold allodynia.

SCN11A SCN10A

6.48e-06289225959819
Pubmed

Detection of a mitochondrial kinase complex that mediates PKA-MEK-ERK-dependent phosphorylation of mitochondrial proteins involved in the regulation of steroid biosynthesis.

MAPK3 STAR

6.48e-06289219426868
Pubmed

Interferon-alpha-induced endogenous superantigen. a model linking environment and autoimmunity.

ERVK-6 ERVK-18

6.48e-06289211672541
Pubmed

Kif26b, a kinesin family gene, regulates adhesion of the embryonic kidney mesenchyme.

WNT11 MAPK3 CDH2

8.86e-061689320439720
Pubmed

An enhancer cluster controls gene activity and topology of the SCN5A-SCN10A locus in vivo.

SCN11A SCN5A SCN10A

1.29e-051889331666509
Pubmed

Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project.

ERVK-18 ERVK-25 ERVK-10

1.29e-051889318664271
Pubmed

PDCD4 interacting with PIK3CB and CTSZ promotes the apoptosis of multiple myeloma cells.

PIK3CB CTSZ

1.94e-05389239190024
Pubmed

A point mutation in the gene for asparagine-linked glycosylation 10B (Alg10b) causes nonsyndromic hearing impairment in mice (Mus musculus).

ALG10 ALG10B

1.94e-05389224303013
Pubmed

A disease mutation reveals a role for NaV1.9 in acute itch.

SCN11A SCN10A

1.94e-05389230395542
Pubmed

Genetic Analysis of SCN11A, SCN10A, and SCN9A in Familial Episodic Pain Syndrome (FEPS) in Japan and Proposal of Clinical Diagnostic Criteria.

SCN11A SCN10A

1.94e-05389238999942
Pubmed

The KBTBD6/7-DRD2 axis regulates pituitary adenoma sensitivity to dopamine agonist treatment.

KBTBD6 KBTBD7

1.94e-05389232572597
Pubmed

High prevalence of concealed Brugada syndrome in patients with atrioventricular nodal reentrant tachycardia.

SCN5A SCN10A

1.94e-05389225998140
Pubmed

Inhibition of ERK activation enhances the repair of double-stranded breaks via non-homologous end joining by increasing DNA-PKcs activation.

PRKDC MAPK3

1.94e-05389223098854
Pubmed

Myosin light-chain kinase contributes to the proliferation and migration of breast cancer cells through cross-talk with activated ERK1/2.

MYLK MAPK3

1.94e-05389218710790
Pubmed

Genome-wide screening, cloning, chromosomal assignment, and expression of full-length human endogenous retrovirus type K.

ERVK-6 ERVK-18

1.94e-05389210516026
Pubmed

N-cadherin regulates cytoskeletally associated IQGAP1/ERK signaling and memory formation.

MAPK3 CDH2

1.94e-05389217785185
Pubmed

ABCB5 is a limbal stem cell gene required for corneal development and repair.

ABCB5 PRKDC

1.94e-05389225030174
Pubmed

Yield of peripheral sodium channels gene screening in pure small fibre neuropathy.

SCN11A SCN10A

1.94e-05389230554136
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

ARHGEF40 LMF2 GRAMD1A NUP133 DGKE TMEM214 EXT2 PRKDC UNC45A TBL3 SLC27A4

2.89e-05942891131073040
Pubmed

Map3k1, Il6st, Gzmk, and Hspb3 gene coexpression network in the mechanism of freezing reaction in mice.

GZMK IL6ST

3.87e-05489221162133
Pubmed

Genome-wide association studies of the PR interval in African Americans.

SCN5A SCN10A

3.87e-05489221347284
Pubmed

Validation study of genetic associations with coronary artery disease on chromosome 3q13-21 and potential effect modification by smoking.

MYLK KALRN

3.87e-05489219706030
Pubmed

Genistein-induced neuronal differentiation is associated with activation of extracellular signal-regulated kinases and upregulation of p21 and N-cadherin.

MAPK3 CDH2

3.87e-05489216149052
Pubmed

The IKr drug response is modulated by KCR1 in transfected cardiac and noncardiac cell lines.

ALG10 ALG10B

3.87e-05489214525949
Pubmed

Allele-specific demethylation at an imprinted mammalian promoter.

INPP5F DNMT3L

3.87e-05489217942418
Pubmed

AC3-33, a novel secretory protein, inhibits Elk1 transcriptional activity via ERK pathway.

C3orf33 MAPK3

3.87e-05489220680465
Pubmed

Human endogenous retrovirus K10: expression of Gag protein and detection of antibodies in patients with seminomas.

ERVK-6 ERVK-10

3.87e-0548927983737
Pubmed

Voltage-Gated Sodium Channel Phosphorylation at Ser571 Regulates Late Current, Arrhythmia, and Cardiac Function In Vivo.

SCN5A CDH2

3.87e-05489226187182
Pubmed

Tenascin-C promotes melanoma progression by maintaining the ABCB5-positive side population.

ABCB5 PRKDC

3.87e-05489220729912
Pubmed

Probing nuclear pore complex architecture with proximity-dependent biotinylation.

NUP133 TMEM214 PRKDC UNC45A

4.70e-057789424927568
Pubmed

High glucose enhances interleukin-6-induced vascular endothelial growth factor 165 expression via activation of gp130-mediated p44/42 MAPK-CCAAT/enhancer binding protein signaling in gingival fibroblasts.

MAPK3 IL6ST

6.44e-05589214676217
Pubmed

Genome- and phenome-wide analyses of cardiac conduction identifies markers of arrhythmia risk.

SCN5A SCN10A

6.44e-05589223463857
Pubmed

Distinct contributions of partial and full EMT to breast cancer malignancy.

PRKDC CDH2

6.44e-05589234847378
Pubmed

Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death.

SCN5A SCN10A

6.44e-05589223872634
Pubmed

Transcriptionally active HERV-K genes: identification, isolation, and chromosomal mapping.

ERVK-6 ERVK-7

6.44e-05589211401426
Pubmed

Early development of electrical excitability in the mouse enteric nervous system.

SCN11A SCN5A

6.44e-05589222875929
Pubmed

Myosin light chain kinase functions downstream of Ras/ERK to promote migration of urokinase-type plasminogen activator-stimulated cells in an integrin-selective manner.

MYLK MAPK3

6.44e-05589210402467
Pubmed

Pain-causing stinging nettle toxins target TMEM233 to modulate NaV1.7 function.

SCN11A SCN10A

6.44e-05589237117223
Pubmed

N-cadherin negatively regulates osteoblast proliferation and survival by antagonizing Wnt, ERK and PI3K/Akt signalling.

MAPK3 CDH2

6.44e-05589220011526
Pubmed

Cloning and characterization of two distinct human extracellular signal-regulated kinase activator kinases, MEK1 and MEK2.

PRKDC MAPK3

6.44e-0558928388392
Pubmed

Genetic variation in T-box binding element functionally affects SCN5A/SCN10A enhancer.

SCN5A SCN10A

6.44e-05589222706305
Pubmed

Wortmannin, a widely used phosphoinositide 3-kinase inhibitor, also potently inhibits mammalian polo-like kinase.

PIK3CB PRKDC

6.44e-05589215664519
Pubmed

Contactin regulates the current density and axonal expression of tetrodotoxin-resistant but not tetrodotoxin-sensitive sodium channels in DRG neurons.

SCN11A SCN10A

9.65e-05689216029194
Pubmed

An animal model of oxaliplatin-induced cold allodynia reveals a crucial role for Nav1.6 in peripheral pain pathways.

SCN11A SCN10A

9.65e-05689223711479
Pubmed

Interleukin-6 stimulates circulating blood-derived endothelial progenitor cell angiogenesis in vitro.

MAPK3 IL6ST

9.65e-05689217519976
Pubmed

PI3Kα-regulated gelsolin activity is a critical determinant of cardiac cytoskeletal remodeling and heart disease.

PIK3CB CDH2

9.65e-05689230568254
Pubmed

Opposing roles of gp130-mediated STAT-3 and ERK-1/ 2 signaling in liver progenitor cell migration and proliferation.

MAPK3 IL6ST

9.65e-05689217256754
Pubmed

Direction selectivity in the retina is established independent of visual experience and cholinergic retinal waves.

SCN11A SCN10A MAPK3

9.99e-053589318498732
Pubmed

The CXC chemokine stromal cell-derived factor activates a Gi-coupled phosphoinositide 3-kinase in T lymphocytes.

PIK3CB MAPK3

1.35e-04789210570282
Pubmed

Tyrosine-phosphorylated and nonphosphorylated sodium channel beta1 subunits are differentially localized in cardiac myocytes.

SCN5A CDH2

1.35e-04789215272007
Pubmed

Active Mek2 as a regulatory scaffold that promotes Pin1 binding to BPGAP1 to suppress BPGAP1-induced acute Erk activation and cell migration.

MAPK3 ARHGAP8

1.35e-04789220179103
Pubmed

Regulation of Wnt/PCP signaling through p97/VCP-KBTBD7-mediated Vangl ubiquitination and endoplasmic reticulum-associated degradation.

KBTBD6 KBTBD7

1.35e-04789233990333
Pubmed

Novel loci associated with PR interval in a genome-wide association study of 10 African American cohorts.

SCN5A SCN10A

1.35e-04789223139255
Pubmed

Pain without nociceptors? Nav1.7-independent pain mechanisms.

SCN11A SCN10A

1.35e-04789224440715
Pubmed

A role for Piezo2 in EPAC1-dependent mechanical allodynia.

SCN11A SCN10A

1.35e-04789223575686
Pubmed

Significant determinants of mouse pain behaviour.

SCN11A SCN10A

1.79e-04889225101983
Pubmed

Cell-autonomous requirements for Dlg-1 for lens epithelial cell structure and fiber cell morphogenesis.

MAPK3 CDH2

1.79e-04889219623611
Pubmed

Loss of cell adhesion causes hydrocephalus in nonmuscle myosin II-B-ablated and mutated mice.

MYLK CDH2

1.79e-04889217429076
Pubmed

Sprouty1 is a critical regulator of GDNF/RET-mediated kidney induction.

WNT11 MAPK3

1.79e-04889215691764
Pubmed

Defining the membrane proteome of NK cells.

LMF2 PEX16 NUP133 SLC7A5 DGKE EXT2 PRKDC PSME2 IL6ST SLC27A4 EHD4

1.95e-041168891119946888
Pubmed

Placental structure, function, and mitochondrial phenotype relate to fetal size in each fetal sex in mice†.

SLC7A5 MAPK3 STAR

1.99e-044489335293971
Pubmed

Fibroblast growth factor receptor 2 (FGFR2) is required for corneal epithelial cell proliferation and differentiation during embryonic development.

MAPK3 CDH2

2.30e-04989225615698
Pubmed

A cell-intrinsic role for TLR2-MYD88 in intestinal and breast epithelia and oncogenesis.

PRKDC IL18R1

2.30e-04989225362351
Pubmed

Two novel EGFP insertion alleles reveal unique aspects of Pax2 function in embryonic and adult kidneys.

WNT11 CDH2

2.30e-04989222410172
Pubmed

Sodium channel Scn1b null mice exhibit prolonged QT and RR intervals.

SCN5A CDH2

2.30e-04989217884088
Pubmed

Dual phosphorylation of phosphoinositide 3-kinase adaptor Grb2-associated binder 2 is responsible for superoxide formation synergistically stimulated by Fc gamma and formyl-methionyl-leucyl-phenylalanine receptors in differentiated THP-1 cells.

PIK3CB MAPK3

2.30e-04989214530346
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

EDEM3 LMF2 GRAMD1A NADK SLC7A5 TMEM214 EXT2 PSME2 CDH2 CTSZ IL6ST

2.47e-041201891135696571
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

LMF2 GRAMD1A PEX16 SLC7A5 DGKE TMEM214 EXT2 PRKDC CDH2 TBL3 SLC27A4

2.51e-041203891129180619
Pubmed

Developmental and cell-specific expression of thyroid hormone transporters in the mouse cochlea.

SLC7A5 TSHR

2.88e-041089221878515
Pubmed

TGFβ pathway is required for viable gestation of Fanconi anemia embryos.

PRKDC MAPK3

2.88e-041089236441774
Pubmed

Seven genes from human chromosome 18 map to chromosome 24 in the bovine.

SERPINB2 CDH2

2.88e-04108928697804
Pubmed

A point mutation in Myh10 causes major defects in heart development and body wall closure.

MYLK CDH2

2.88e-041089224825879
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

LMO7 CORO2A GRAMD1A NUP133 SLC7A5 DGKE PRKDC PSME2 UNC45A SPECC1 SLC27A4 EHD4

3.02e-041440891230833792
Pubmed

The global gene-expression profiles of U-937 human macrophages treated with Tat peptide and Tat-FITC conjugate.

SLC30A4 CDH2 CTSZ

3.27e-045289322632162
Pubmed

In vitro capture and characterization of embryonic rosette-stage pluripotency between naive and primed states.

MAPK3 DNMT3L

3.51e-041189232367046
Pubmed

Evidence for similar expression of protein C inhibitor and the urokinase-type plasminogen activator system during mouse testis development.

SERPINB2 STAR

3.51e-041189214645112
Pubmed

Wnt-11 signalling controls ventricular myocardium development by patterning N-cadherin and beta-catenin expression.

WNT11 CDH2

3.51e-041189219622544
Pubmed

Dlg-1 Interacts With and Regulates the Activities of Fibroblast Growth Factor Receptors and EphA2 in the Mouse Lens.

MAPK3 CDH2

3.51e-041189226906157
Pubmed

The endocytic recycling regulatory protein EHD1 Is required for ocular lens development.

CDH2 EHD4

3.51e-041189226455409
Cytoband1q23.3

CFAP126 CD244 ERVK-18

1.22e-04498931q23.3
GeneFamilySodium voltage-gated channel alpha subunits

SCN11A SCN5A SCN10A

3.03e-0696131203
GeneFamilyAlpha-1,2-glucosyltransferases

ALG10 ALG10B

1.12e-052612448
ToppCellCiliated_cells-B-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

WDR38 TMCO5A CFAP126 ODAD4 BICC1 LRRC9

3.65e-071498366399c5a2f06d79f020dece252526f1c0c110d569
ToppCellCiliated_cells-A-HP_01|World / lung cells shred on cell class, cell subclass, sample id

WDR38 CFAP126 ABCA13 ODAD4 AGBL2 LRRC9

5.34e-071598360c65ae6140abd48c79b04758a6217709ddd15385
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 TSHR ARHGAP8 CDH2 BICC1

5.43e-061358358521107817df49efd9a2e81078c8535ed33e729c
ToppCellControl-Myeloid-Dendritic_cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

A1BG ABCB5 SLC7A5 CDH2 IL18R1

7.19e-06143835bb8d4c335682d1a6798bed0de8bb0603054a4944
ToppCellControl-Myeloid-Dendritic_cells-pDC|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

A1BG ABCB5 SLC7A5 CDH2 IL18R1

7.69e-06145835bab85a72142b6257f7d424e5301f65b6dcdf745d
ToppCellCiliated_cells-A-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

WDR38 CFAP126 SCN5A ODAD4 LRRC9

1.03e-051548353b938e23324f7edb56797b4a76fb96ff588142cf
ToppCellLPS_only-Epithelial_airway-Ciliated_cells-Ciliated|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

WDR38 CFAP126 ODAD4 TSHR LRRC9

1.03e-051548359ca71d440c4f87781e6525b8141e7d8d470b6a8e
ToppCellLPS_only-Epithelial_airway-Ciliated_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

WDR38 CFAP126 ODAD4 TSHR LRRC9

1.03e-0515483558072ce422d09f2de602580325eaac6c4ec6c136
ToppCellICU-SEP-Lymphocyte-T_NK-dnT|ICU-SEP / Disease, Lineage and Cell Type

KALRN ABCB5 GZMK AGBL2 ALG10B

1.48e-0516683596d92316cee20b722fe782db9dafcceb8f2c220b
ToppCellfacs-Marrow-T-cells-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF20A GPR15 ABCA13 PIK3CB SPECC1

1.71e-05171835913bae728b5e653771a27c79a309eb023699f1d0
ToppCellfacs-Marrow-T-cells-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF20A GPR15 ABCA13 PIK3CB SPECC1

1.71e-05171835f28b2336057e353b96a6ff4581ec9fd0ca0789d9
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KIF20A GPR15 CORO2A GZMK IL18R1

1.71e-05171835846a9acfff0bf0a9baf65dc07b7d7a9217ed6598
ToppCellfacs-BAT-Fat-18m-Lymphocytic-T_cell|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR15 GZMK PSME2 IL18R1 ALG10B

1.91e-05175835bf1ef77d5fed2135ac83a4f7e445ab59d1538696
ToppCellCiliated_cells-A-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

WDR38 CFAP126 ODAD4 AGBL2 BICC1

2.07e-05178835255473ee6df8a13079fb3bb61038162a40cb4c2c
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_INF-A|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

RAPGEF6 BBS7 MAPK3 IL18R1 CTSZ

2.13e-0517983506d412fc096d88de168969466ce422f0ab5553b2
ToppCellHealthy_donor-MAIT|Healthy_donor / disease group, cell group and cell class (v2)

WNT11 GZMK SLC7A5 CDH2 IL18R1

2.31e-05182835ac7c83464487ecde3df6804a99551307bd768f21
ToppCellCiliated_cells-B-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

WDR38 CFAP126 ABCA13 ODAD4 AGBL2

2.49e-051858354fc7113d3dadc716ec5a8e62b58543cc00ce5b16
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 PIK3CB CDH2 DNAH14 BICC1

2.76e-05189835904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCelldistal-Epithelial-Proximal_Ciliated|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

WDR38 CFAP126 ABCA13 ODAD4 AGBL2

3.21e-05195835abe7998421dc59bdae35c0c2251c4a1ebef5e021
ToppCelldistal-Epithelial-Proximal_Ciliated-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

WDR38 CFAP126 ABCA13 ODAD4 AGBL2

3.21e-051958350e3f74e0877d33c11f048b9be8394596cf5c9c4c
ToppCellCOVID-19-Epithelial|COVID-19 / Condition, Lineage and Cell class

WDR38 CFAP126 LMO7 ABCA13 ODAD4

3.37e-0519783518fd7344628a87d5c7ef5efb66e260a4136245bf
ToppCelldistal-3-Epithelial-Proximal_Ciliated|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

WDR38 CFAP126 ABCA13 ODAD4 AGBL2

3.37e-0519783515b4d1203943ce90a7083178d4a4284d9b323071
ToppCellmLN-T_cell-Th1|mLN / Region, Cell class and subclass

ARHGEF40 CFAP126 SLC17A1 SLC7A5 STAR

3.45e-051988357627b7c3a248da2bd5e1e6f7c226e5fd0bc92113
ToppCellmLN-(1)_T_cell-(12)_Th1|mLN / shred on region, Cell_type, and subtype

ARHGEF40 CFAP126 SLC17A1 SLC7A5 STAR

3.45e-051988351fe8257233232b264b9ca630c2d92c509a195353
ToppCellBAL-Mild-Epithelial-Epithelial|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ST6GALNAC1 WDR38 CFAP126 LMO7 ABCA13

3.53e-051998351ee4010d8557564e25e8ee00b914c2dfd9037838
ToppCellBAL-Mild-Epithelial-Epithelial|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

ST6GALNAC1 WDR38 CFAP126 LMO7 ABCA13

3.53e-051998351df69c0cb5f759f6a2152521842506a75bb95cae
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_ciliated-Deuterosomal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

KIF20A CFAP126 AGBL2 STAR LRRC9

3.53e-0519983592778939e9d06599c7d06cfd8f4362b97ed0606b
ToppCellMild-Epithelial-Epithelial-|Mild / Condition, Lineage, Cell class and cell subclass

ST6GALNAC1 WDR38 CFAP126 LMO7 ABCA13

3.53e-0519983581115bbd2c10bfdd38376d2075f03a59c31870d2
ToppCellBAL-Mild-Epithelial|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ST6GALNAC1 WDR38 CFAP126 LMO7 ABCA13

3.53e-0519983574087b4b5e567310fc4ac58fb267ff651a180680
ToppCellBAL-Mild-Epithelial|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

ST6GALNAC1 WDR38 CFAP126 LMO7 ABCA13

3.53e-0519983500b5ce099c50a5e1786ce2b3a06ee0931a8205a4
ToppCellMild-Epithelial|Mild / Condition, Lineage, Cell class and cell subclass

ST6GALNAC1 WDR38 CFAP126 LMO7 ABCA13

3.53e-05199835ec5fff80e2a8a94fbaf1fdcc6d45c8d7c6252e18
ToppCellMild-Epithelial-Epithelial|Mild / Condition, Lineage, Cell class and cell subclass

ST6GALNAC1 WDR38 CFAP126 LMO7 ABCA13

3.53e-0519983591308b255783ad4029e5575028c18d7550832c51
ToppCellMild_COVID-19-Epithelial|Mild_COVID-19 / Disease group,lineage and cell class (2021.01.30)

ST6GALNAC1 WDR38 CFAP126 LMO7 ABCA13

3.53e-0519983572689bda7476930887ae007682fcab27f956f050
ToppCellLPS_IL1RA_TNF-Epithelial_airway-airway_epithelial-Ciliated|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ST6GALNAC1 WDR38 CFAP126 ODAD4 LRRC9

3.62e-0520083596701a4d57753f5ec0dd5c7550054bbcc946bc5f
ToppCellBiopsy_Other_PF-Epithelial-Differentiating_Ciliated|Biopsy_Other_PF / Sample group, Lineage and Cell type

ST6GALNAC1 WDR38 CFAP126 ABCA13 ODAD4

3.62e-05200835f7b4581d958afbd68f9045af619aaca0ab463439
ToppCellLPS_IL1RA_TNF-Epithelial_airway-airway_epithelial|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ST6GALNAC1 WDR38 CFAP126 ODAD4 LRRC9

3.62e-05200835da12821e8a0657869ca0f75d351cce2d7605a505
ToppCellTracheal-10x3prime_v2-Epithelial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ST6GALNAC1 WDR38 CFAP126 LMO7 ABCA13

3.62e-05200835e1da1b15d2ca06796ee1ab7cef586ae0b4dc0a0a
ToppCellLPS_IL1RA_TNF-Epithelial_airway|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ST6GALNAC1 WDR38 CFAP126 ODAD4 LRRC9

3.62e-0520083572c1d9eeaed4b3ee6b6c602e8aa29efc2e8744eb
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Vipr2|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

A1BG NLRP14 TSHR MEFV

7.28e-051198346425425b2e622c97b6c74c530ccbfe394d3b202d
ToppCellLymphoid-NK_cells|World / shred on cell class and cell subclass (v4)

CD244 CORO2A GRAMD1A IL18R1

1.06e-04131834b0b62392d1637601115e85f5584fdcd5dbd0c778
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD244 CORO2A GZMK IL18R1

1.44e-04142834efe2418436ad1320b8e8fce38619ac65516ef077
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD244 CORO2A GZMK IL18R1

1.48e-04143834138033ff447a61a1bc289b21db82151dcc6a4c7e
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

KALRN WNT11 PRKDC STAR

1.52e-041448341c001a5a3bbe4ecbce8305f8b260e933033550dd
ToppCellGlobus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Sphkap|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

KBTBD6 SCN10A MEFV

1.56e-0456833af55596513ddbe60b08648b27e41a7b65e3da58c
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KIF20A GPR15 CORO2A MEFV

1.60e-0414683445d7cb73776e60d22f335a651845e21e16948fcc
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD244 CORO2A GZMK IL18R1

1.69e-041488343aa47398cb805c6c6e16b375cc3e9c7f04bb91f4
ToppCellControl-Lymphocytic_NKT-iNKT/MAIT-T-cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CD244 GZMK IL18R1 SLC27A4

1.69e-04148834003e10bf477984248211b99d75daa8f7dcdb12c8
ToppCellLPS-antiTNF-Epithelial_airway-Ciliated_cells-Ciliated|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

WDR38 CFAP126 ODAD4 LRRC9

1.69e-04148834d61123f0c811287843d066b932b4a9ff09c07c5b
ToppCellLPS-antiTNF-Epithelial_airway-Ciliated_cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

WDR38 CFAP126 ODAD4 LRRC9

1.69e-04148834c8e93b87212f55774223caa385859c566fa1981f
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD244 CORO2A GZMK IL18R1

1.82e-041518341525422afadff68a1525ced6d5db45fdea450678
ToppCellLPS-IL1RA-Epithelial_airway-Ciliated_cells|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

WDR38 CFAP126 ODAD4 LRRC9

1.82e-0415183481cf939ed4df9574fbfff265e109cb9f947d7e6e
ToppCellLPS-IL1RA-Epithelial_airway-Ciliated_cells-Ciliated|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

WDR38 CFAP126 ODAD4 LRRC9

1.82e-041518349cbcbbc22965a9f0be8364e733d205dd64f2a533
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD244 CORO2A GZMK IL18R1

1.87e-04152834ed6df77ba04b715e12c2e1591b4a1e894ca49d25
ToppCellmild_COVID-19_(asymptomatic)-MAIT|World / disease group, cell group and cell class (v2)

LRRC39 GZMK SLC7A5 IL18R1

1.92e-041538342b4c69f6db17927d6506a645ac058133e60b0103
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-Klrb1a/b/c(-)_NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA13 GZMK SCN10A IL18R1

1.92e-04153834cb144b8c487286384b47fdff88ff98fcf0508899
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

WDR38 CFAP126 ODAD4 LRRC9

2.02e-041558345f1e2195a6b831e1b636f5cc3a282ca423721822
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells-Ciliated|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

WDR38 CFAP126 ODAD4 LRRC9

2.02e-041558340944429459f642a1bcc56edc1ec28aaecde3e2dc
ToppCell10x5'-GI_large-bowel-Lymphocytic_T_CD8-Trm/em_CD8|GI_large-bowel / Manually curated celltypes from each tissue

MYLK GZMK CEP70 ARHGAP8

2.12e-04157834d85304af4cd3b8aaedc5362a8223537e1b9dbec2
ToppCellThalamus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pou6f2-Inhibitory_Neuron.Gad1Gad2.Pou6f2-Pax6_(Zona_incerta_(ZI))|Thalamus / BrainAtlas - Mouse McCarroll V32

ABCB5 UBTFL1 DNMT3L

2.12e-046283302f0398e18bd61fbfa03bce71ae77e106181abee
ToppCellThalamus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pou6f2-Inhibitory_Neuron.Gad1Gad2.Pou6f2-Pax6_(Zona_incerta_(ZI))-|Thalamus / BrainAtlas - Mouse McCarroll V32

ABCB5 UBTFL1 DNMT3L

2.12e-04628338fdbced7a2baa1bfb5b1e204128234424a872fe6
ToppCellThalamus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pou6f2|Thalamus / BrainAtlas - Mouse McCarroll V32

ABCB5 UBTFL1 DNMT3L

2.12e-0462833ff68e007b8b2af4c7fb09139aed92e86907a05da
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sst|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

A1BG SCN11A DNMT3L

2.22e-046383355f11bb2970a8159166e71af34a0446ecee594e6
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Granulocytic-Mast_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGEF40 ARRDC5 SLC7A5 IL18R1

2.27e-04160834fe9970c160159b35f6599ed13c89cfb49264d554
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Chat-Inhibitory_Gad1Gad2Chat_Htr3a.Chat_(Interneuron,_Cholinergic_(candidate__CGE-derived_2))|Hippocampus / BrainAtlas - Mouse McCarroll V32

LRRC39 TSHR C4orf36

2.33e-0464833bbce496e9682cd74e3163a64d9d20bc6368d3e48
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Chat-Inhibitory_Gad1Gad2Chat_Htr3a.Chat_(Interneuron,_Cholinergic_(candidate__CGE-derived_2))-|Hippocampus / BrainAtlas - Mouse McCarroll V32

LRRC39 TSHR C4orf36

2.33e-046483391371907b75b0b97d2ebd57d4048a81f5e5fd694
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Chat|Hippocampus / BrainAtlas - Mouse McCarroll V32

LRRC39 TSHR C4orf36

2.33e-04648333e464bd87c15ba34c174e11fbe8d88e9a8735caf
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_12|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MYLK SLC7A5 SPECC1 IL18R1

2.33e-041618341670108afc0af90861eb80a84e59995571c0da1b
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_12|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MYLK SLC7A5 SPECC1 IL18R1

2.33e-041618341d446f5ba57d84949823a35cbedaee8f448fe40f
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c02-NCAM1|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CATSPER2 GZMK IL18R1 STAR

2.44e-041638341c014e373667be290d7fb5d24c06c6f313ac8fa3
ToppCell10x5'-bone_marrow-Lymphocytic_T_CD4-Tfh|bone_marrow / Manually curated celltypes from each tissue

RAPGEF6 LMO7 NUP133 IL6ST

2.62e-041668349ac5267d3a53a96dec9eae3bc01acba4750742c8
ToppCellSevere-Lymphoid-NK-innate_T|Severe / Condition, Lineage, Cell class and cell subclass

C3orf33 ARRDC5 GZMK IL18R1

2.62e-04166834ee5ee75131fc0e22da0ceba3917f2104516af4b7
ToppCellPND14-Immune-Immune_Myeloid-DC-cDC2-cDC2_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KIF20A CORO2A SLC30A4 MEFV

2.74e-04168834b7cd33f5da4f37b9384fc3bd3ca01fbc790accfc
ToppCell3'_v3-Lung-Lymphocytic_Invariant-Inducer-like|Lung / Manually curated celltypes from each tissue

GZMK CDH2 IL18R1 BICC1

2.74e-04168834b9bde6f542d730682d34a80e1f7f1609e5c699c7
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Hematologic-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3CB SLC7A5 ODAD4 MEFV

2.80e-041698344e1322cc5e1733e9fb19e08f739a30206f43cea8
ToppCelldroplet-Thymus-nan-18m-Lymphocytic-DN4_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAPGEF6 GRAMD1A GZMK PSME2

2.87e-0417083490f7640f04672c800cb28aea50004b1bb0565e8a
ToppCellfacs-Large_Intestine-Proximal-18m-Epithelial-enterocyte_of_epithelium_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYLK CORO2A PSME2 SLC27A4

2.87e-0417083475b0486620cab838d3feb1c3aa965b487a906618
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD244 CORO2A GRAMD1A IL18R1

2.87e-04170834da4dde7d0491ccc298cec7474a6a76ff3db36a4c
ToppCellSubstantia_nigra-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Shox2_(peripeduncular_nucleus_&_posterior_intralaminar_thalamic_nucleus_(PP_&_PIL))|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

TMCO5A IL18R1 DNMT3L

2.91e-046983372031d97bf3a3f3e8fe2ad1130c766e39b3b4c46
ToppCellSubstantia_nigra-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Shox2_(peripeduncular_nucleus_&_posterior_intralaminar_thalamic_nucleus_(PP_&_PIL))-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

TMCO5A IL18R1 DNMT3L

2.91e-046983320bda1222efe784b025c6b311a7813b3b562ec71
ToppCell368C-Lymphocytic-ILC|368C / Donor, Lineage, Cell class and subclass (all cells)

CD244 KBTBD6 CORO2A TIGD1

2.93e-041718343b3143e4aa6520ee9c6b6f2482206ad3d8205d14
ToppCellfacs-Marrow-Granulocytes|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA13 NADK MAPK3 SLC27A4

2.93e-041718341701dedf0c18751db6c9fee3d93fff150ed0e17f
ToppCell368C-Lymphocytic-ILC-ILC-2|368C / Donor, Lineage, Cell class and subclass (all cells)

CD244 KBTBD6 CORO2A TIGD1

2.93e-04171834fd01076574dcc82bfd4a1538812500543b16794f
ToppCellHealthy/Control-MAIT|World / Disease group and Cell class

WNT11 GZMK SLC7A5 IL18R1

2.93e-0417183461515114b17816a8f9ef6a57262eb9e977b6ede4
ToppCellHealthy_donor-MAIT|World / disease group, cell group and cell class (v2)

GZMK SLC7A5 CDH2 IL18R1

3.00e-041728346524eb2be1c78700ad367e62624a4d7eb48b54f0
ToppCelldroplet-Marrow-nan-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA13 PIK3CB SPECC1 SLC27A4

3.00e-04172834d354424c1f861b6607dfd63b9724f4c237b30275
ToppCellHealthy/Control-MAIT|Healthy/Control / Disease group and Cell class

WNT11 GZMK SLC7A5 IL18R1

3.06e-0417383456247c1e07477a8922fe2e3950ae05e2217fd77c
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LMO7 IL18R1 SLC27A4 C4orf36

3.20e-0417583496219e58dcb327fd27190be78193e7a0d611e62b
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LMO7 IL18R1 SLC27A4 C4orf36

3.20e-04175834cb974fbebe8cb58c7d3f7defabb4e056f2fee5fa
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KIF20A GPR15 CD244 CORO2A

3.20e-04175834ae7e0448ffd11b8908d0f6d99ff737faf5eca4bf
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TMCO5A ODAD4 SPECC1 BICC1

3.27e-0417683487de432c680b80555342afac864599bbc002c040
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell_prolif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DGKE MAPK3 USP1 SPECC1

3.27e-041768341df7b6ce2519ad99bacbbaf1a8d5929e11513faa
ToppCellPND10-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CORO2A CEP70 USP1 MEFV

3.27e-0417683490f8bb11f339f67f08692a0c33dd420f5cda2861
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 PIK3CB CDH2 BICC1

3.34e-04177834da8802a6351d3e510822f82e2fde8a4314a2216e
ToppCellControl-T/NK-NK|Control / Disease group,lineage and cell class (2021.01.30)

ABCB5 GZMK CDH2 IL18R1

3.41e-04178834079fd19bdeed86bf985c4083af432432d66ad546
ToppCellCiliated_cells-A-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

CFAP126 KALRN ABCA13 SLC27A4

3.48e-041798341c41314b6fcfcac8d62034e7037570120d58f20f
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC17A1 ABCA13 CDH2 BICC1

3.48e-0417983458ae5a97fe2a14e1c6fdeb886397eb06fdaf0428
ToppCell368C-Lymphocytic-ILC-ILC-2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CD244 KBTBD6 CORO2A TIGD1

3.56e-04180834eb5a57604c7f2ad256c300085dbf5069d0ae1ad0
ToppCell368C-Lymphocytic-ILC|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CD244 KBTBD6 CORO2A TIGD1

3.56e-04180834ddba4dc3bbcfe4e4a22400be73bbc62d3ff27d3c
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LMO7 ABCA13 CEP70 DNAH14

3.63e-04181834576da14ab3107f89e1f44a4a439d1bef5bb42370
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 PIK3CB CDH2 BICC1

3.63e-04181834071f9bb5d39070cdc473d9b0e094d196bc702b56
DrugCocaine

SCN11A SCN5A SCN10A

2.68e-068843DB00907
Drug3-alpha-Hydroxy-5-beta-androstan-17-one [53-42-9]; Up 200; 13.8uM; PC3; HT_HG-U133A

STRN3 GPR15 SCN10A PEX16 DGKE TSHR CTSZ

7.88e-061958474298_UP
Diseasegeneralized epilepsy with febrile seizures plus 2 (implicated_via_orthology)

SCN11A SCN5A SCN10A

2.19e-0610793DOID:0111294 (implicated_via_orthology)
DiseaseDravet syndrome (implicated_via_orthology)

SCN11A SCN5A SCN10A

2.19e-0610793DOID:0080422 (implicated_via_orthology)
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

SCN11A SCN5A SCN10A

3.99e-0612793DOID:0060170 (implicated_via_orthology)
DiseaseLong Qt Syndrome 2

ALG10 ALG10B

2.12e-053792C3150943
DiseasePAROXYSMAL EXTREME PAIN DISORDER

SCN11A SCN10A

2.12e-053792C1833661
DiseasePrimary Erythermalgia

SCN11A SCN10A

2.12e-053792C0014805
DiseaseBrugada ECG Pattern

SCN5A SCN10A

4.23e-054792C1721096
Diseaseleptin measurement

GPR15 ALG10 BICC1 ALG10B

6.77e-0581794EFO_0005000
Diseasenonsyndromic deafness (implicated_via_orthology)

ALG10 ALG10B

1.05e-046792DOID:0050563 (implicated_via_orthology)
DiseaseHereditary Sensory Autonomic Neuropathy, Type 5

SCN11A SCN10A

1.47e-047792C0020075
Diseaseelectrocardiography, PR interval

SCN5A SCN10A

1.47e-047792EFO_0004327, EFO_0004462
DiseaseCongenital Pain Insensitivity

SCN11A SCN10A

1.47e-047792C0002768
Diseasesupraventricular ectopy

SCN5A SCN10A

2.52e-049792EFO_0009277
DiseasePR interval

ARHGEF40 KALRN ARRDC5 ABCB5 WNT11 SCN5A SCN10A

3.67e-04495797EFO_0004462
DiseaseCongenital long QT syndrome

SCN5A ALG10B

3.83e-0411792cv:C1141890
Diseaseintraocular pressure measurement

TMCO5A KALRN LMO7 ERVK13-1 KBTBD7 BICC1 C4orf36

4.33e-04509797EFO_0004695
DiseaseLong QT syndrome

SCN5A ALG10B

4.59e-0412792cv:C0023976
DiseaseBrugada Syndrome 1

SCN5A SCN10A

5.42e-0413792C4551804
DiseaseSchizophrenia

ST6GALNAC1 A1BG RAPGEF6 ABCA13 PIK3CB ERVK-8 MAPK3 IL18R1 DNMT3L

5.84e-04883799C0036341
DiseaseT wave morphology measurement

SCN5A SCN10A

6.31e-0414792EFO_0008398
Diseaseresting heart rate

ARHGEF40 SCN5A SCN10A CDH2

6.99e-04149794EFO_0004351
DiseaseP wave duration

SCN5A SCN10A

7.27e-0415792EFO_0005094
DiseaseRomano-Ward Syndrome

SCN5A SCN10A

8.29e-0416792C0035828
Diseaseepilepsy (implicated_via_orthology)

SCN11A KALRN SCN5A SCN10A

9.77e-04163794DOID:1826 (implicated_via_orthology)
DiseaseBrugada syndrome

SCN5A SCN10A

1.18e-0319792MONDO_0015263
Diseaseneutrophil percentage of leukocytes

CD244 KALRN ERAP2 SLC7A5 PRKDC IL18R1 EHD4

1.25e-03610797EFO_0007990
DiseaseMechanical Allodynia

SCN11A SCN10A MAPK3

1.51e-0384793C2936719
DiseaseAllodynia

SCN11A SCN10A MAPK3

1.51e-0384793C0458247
DiseaseHyperalgesia, Secondary

SCN11A SCN10A MAPK3

1.51e-0384793C0751212
DiseaseHyperalgesia, Primary

SCN11A SCN10A MAPK3

1.51e-0384793C0751211
DiseaseHyperalgesia, Thermal

SCN11A SCN10A MAPK3

1.51e-0384793C0751214
DiseaseTactile Allodynia

SCN11A SCN10A MAPK3

1.51e-0384793C0751213
DiseaseHyperalgesia

SCN11A SCN10A MAPK3

1.51e-0384793C0020429
DiseaseBrugada Syndrome (disorder)

SCN5A SCN10A

1.88e-0324792C1142166
Diseasemaximal oxygen uptake measurement

SCN10A TSHR

2.21e-0326792EFO_0004887

Protein segments in the cluster

PeptideGeneStartEntry
NVLPKVLGRSTLWKL

TMCO5A

256

Q8N6Q1
LALIQITTSKPVRKW

BBS7

216

Q8IWZ6
WRVPLTTKTNKTKGL

ERVK13-1

36

Q9NX77
SPEIKLKWTSSIAQL

ARHGEF40

1356

Q8TER5
LLESTNTKLWPLKLT

CATSPER2

131

Q96P56
NTKLWPLKLTLEVAA

CATSPER2

136

Q96P56
NIKRKGAWPSTLLSV

CTSZ

106

Q9UBR2
QSSKLAAKWPTKLVK

DNMT3L

351

Q9UJW3
VKGWKLTLVTLSTSP

ABCB5

201

Q2M3G0
KKATPIKLIWSLVAL

GPR15

186

P49685
LTKKYQTWIKSNLVP

GZMK

246

P49863
LLSASTRAWKPQSKL

SPECC1

931

Q5M775
LLLFASIKAPQWTKK

ABCA13

3936

Q86UQ4
LLSPSKIKTFLSLVW

ALG10B

306

Q5I7T1
VGTKTKLSTLTLLWP

DHX30

271

Q7L2E3
TQIAWPSKLKIGAKS

BICC1

86

Q9H694
KQPWSLVKSLIEKNS

GRAMD1A

501

Q96CP6
STKKAEPLTWAQLKK

HERV-K104

41

P61576
SIWPSAKILTQVSKL

LRRC9

861

Q6ZRR7
WTQLSKLLELTGPKS

A1BG

101

P04217
WKIALSPITKLSVCK

NUP133

126

Q8WUM0
PQSLKLLKSHRVLKW

IL18R1

486

Q13478
PATIIWTLNGKTLKT

MYLK

1126

Q15746
LPWSLTSLKAKVPII

ARRDC5

301

A6NEK1
LPLWLSTTNQSISKK

EDEM3

496

Q9BZQ6
EWKTLPSSLLKLNQL

LRRC39

71

Q96DD0
QRLTWNKSPKSVLVI

NADK

96

O95544
QKLLSIIKSQGWLPL

FAM205A

76

Q6ZU69
KRSTNTLKKWLTSPV

KALRN

1761

O60229
FQFLKLTTWILPKIT

HERVK_113

441

P63132
KPKWLLQGIFSTTVL

SLC7A5

481

Q01650
LTRKIQSWKLGTTVP

LMO7

641

Q8WWI1
TSKLPNSVLGKIWKL

EHD4

476

Q9H223
LQSLPSKTKVAWAKL

MAPK3

281

P27361
KWTTPQEIKQKIQLL

MEFV

546

O15553
QKLLLITSTTPQWKK

KBTBD7

566

Q8WVZ9
FQFLKLTTWILPKIT

ERVK-7

441

P63135
FQFLKLTTWILPKIT

ERVK-6

441

Q9BXR3
FQFLKLTTWILPKIT

ERVK-18

441

Q9QC07
LSSILKLTWTNPSIK

IL6ST

236

P40189
KLTWTNPSIKSVIIL

IL6ST

241

P40189
KSLKTLSAELVPWLN

CEP70

411

Q8NHQ1
TIKIWSIPKQLLTRN

CORO2A

106

Q92828
LQKEKLLWPISLSSA

AGBL2

71

Q5U5Z8
TGKAWLQKELKPSQL

C3orf33

126

Q6P1S2
SLTKWIQKNPDLLKA

CFAP126

91

Q5VTH2
LQKKPNWATAKLLLS

DNAH14

2386

Q0VDD8
ETITKNIKWLEKNLP

ERAP2

936

Q6P179
SKLGKQWTPLIILAN

DGKE

211

P52429
LAKTWSTNLANIKLP

C4orf36

31

Q96KX1
LKPNLKVNLWKSDSS

INPP5F

816

Q9Y2H2
TKVDSIAWKKLLPSQ

CD244

46

Q9BZW8
TQEKWQVAVKLSLKP

CDH2

111

P19022
QKLLLITSRTPQWKK

KBTBD6

566

Q86V97
SWVKTQTKGKIPNLL

SERPINB2

171

P05120
KKLPVSLSQQKLLTW

PEX16

71

Q9Y5Y5
LWNLQKTVPAKKSAS

STRN3

506

Q13033
WTLLKPSLIKCLAVS

RAPGEF6

1326

Q8TEU7
DKQSKWSGIPQLLLK

TRPC4AP

66

Q8TEL6
KKTATSWPKALLATL

LMF2

301

Q9BU23
KIPLAKTTLEKTWLF

ODAD4

386

Q96NG3
KAILKSLPVWAISTG

SLC17A1

256

Q14916
FKLAKSWPTLNTLIK

SCN5A

816

Q14524
TITNIPKLKASWRQL

SETD6

401

Q8TBK2
KASKSLWLQKLFLPN

ST6GALNAC1

286

Q9NSC7
LSLLALVKPEVWTLK

PSME2

101

Q9UL46
QSLPKLLLSIKWNKL

PIK3CB

571

P42338
LLSPSKIKTFLSLVW

ALG10

306

Q5BKT4
FQFLKLTTWILPKIT

ERVK-25

441

P63136
SKSVISLLEKRKLPW

ZNF542P

16

Q5EBM4
TSQVLSKWDPIILKN

UTP14C

136

Q5TAP6
KVKLDLWLKTLSPEN

UBTFL1

281

P0CB47
SPVWKTLQKIKLNSD

SPO16

161

Q5VVC0
LSTLTGVWKKLIPTL

TIGD1

396

Q96MW7
LLFSKLVLKLPWTQV

SLC27A4

11

Q6P1M0
AGSPSKTKLTWLLSI

STAR

231

P49675
LKPLLSNEVIWLDSK

KIF20A

201

O95235
LAKSWPTLNTLIKII

SCN10A

766

Q9Y5Y9
VKLWPLPKALLSKNT

TBL3

446

Q12788
VSKVPSLSKLLVVWN

EXT2

476

Q93063
FQFLKLTTWILPKIT

ERVK-10

441

P10266
LLSSWEQIPKKVQKS

TMEM214

421

Q6NUQ4
FQFLKLTTWILPKIT

ERVK-8

441

P63133
IFIWSKLQLKSNPSK

ZNF654

301

Q8IZM8
TTLLNTSPEGWKLLK

PRKDC

1346

P78527
SFIKVLWNILKPLIS

ARHGAP8

146

P85298
HIWKPTTSSLLIQLK

WDR38

216

Q5JTN6
LTLLALWLSSKSPTK

SLC30A4

156

O14863
KWLALSKTPSALALN

WNT11

26

O96014
AKSWPTLNTLIKIIG

SCN11A

681

Q9UI33
KDNWSPALTISKVLL

UBE2E1

136

P51965
KSLKDPNNSLTLWVI

UNC45A

326

Q9H3U1
LLTPLKLSLEEWSTK

USP1

556

O94782
NTWTLKKLPLSLSFL

TSHR

256

P16473
KKILKTSLPTNTWDG

NLRP14

641

Q86W24