Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionstructural constituent of tooth enamel

AMELX AMELY

2.44e-056262GO:0030345
GeneOntologyMolecularFunctiontranscription coactivator activity

NCOA1 NCOA6 BRD4 PML NPAT

3.94e-05303265GO:0003713
GeneOntologyMolecularFunctionhydroxyapatite binding

AMELX AMELY

4.54e-058262GO:0046848
GeneOntologyMolecularFunctiontranscription coregulator activity

NCOA1 NCOA6 BRD4 RBFOX2 PML NPAT

6.89e-05562266GO:0003712
GeneOntologyMolecularFunctionextracellular matrix structural constituent

AMELX AMELY COL8A1 COL11A2

9.67e-05188264GO:0005201
GeneOntologyMolecularFunctionsodium ion binding

AMELX AMELY

1.47e-0414262GO:0031402
GeneOntologyMolecularFunctionextracellular matrix structural constituent conferring compression resistance

AMELX AMELY

4.06e-0423262GO:0030021
GeneOntologyMolecularFunctionnuclear retinoid X receptor binding

NCOA1 NCOA6

4.06e-0423262GO:0046965
GeneOntologyMolecularFunctionalkali metal ion binding

AMELX AMELY

5.20e-0426262GO:0031420
GeneOntologyMolecularFunctionprotein-macromolecule adaptor activity

NCOA1 NCOA6 COL11A2 BRD4 RBFOX2 PML NPAT

5.43e-041160267GO:0030674
GeneOntologyMolecularFunctionchromatin-protein adaptor activity

NCOA6 BRD4

1.30e-0341262GO:0140463
GeneOntologyMolecularFunctionmolecular adaptor activity

NCOA1 NCOA6 COL11A2 BRD4 RBFOX2 PML NPAT

1.37e-031356267GO:0060090
GeneOntologyMolecularFunctionextracellular matrix structural constituent conferring tensile strength

COL8A1 COL11A2

1.63e-0346262GO:0030020
GeneOntologyMolecularFunctionnuclear estrogen receptor binding

NCOA1 NCOA6

2.16e-0353262GO:0030331
GeneOntologyMolecularFunctionnuclear retinoic acid receptor binding

NCOA1 NCOA6

2.32e-0355262GO:0042974
GeneOntologyMolecularFunctionchromatin binding

NCOA1 ANKRD17 NCOA6 TOX4 BRD4

2.36e-03739265GO:0003682
GeneOntologyMolecularFunctionnuclear receptor coactivator activity

NCOA1 NCOA6

2.85e-0361262GO:0030374
GeneOntologyMolecularFunctionSMAD binding

DROSHA PML

5.57e-0386262GO:0046332
GeneOntologyBiologicalProcessanimal organ morphogenesis

SOX5 FGD1 ETV5 AMELX AMELY COL8A1 COL11A2 PML ESRP1

1.48e-051269269GO:0009887
GeneOntologyBiologicalProcessmammary gland development

ETV5 NCOA1 ARHGAP5 PML

4.79e-05162264GO:0030879
GeneOntologyCellularComponentcomplex of collagen trimers

COL8A1 COL11A2

3.08e-0421262GO:0098644
GeneOntologyCellularComponentbasement membrane

AMELX AMELY COL8A1

4.57e-04122263GO:0005604
GeneOntologyCellularComponentcollagen-containing extracellular matrix

AMELX AMELY COL8A1 COL11A2

3.92e-03530264GO:0062023
MousePhenoshort Tomes' process

AMELX AMELY

2.59e-062232MP:0030513
MousePhenoabnormal Tomes' process morphology

AMELX AMELY

7.76e-063232MP:0030512
MousePhenolarge mandible

AMELX AMELY

1.55e-054232MP:0030050
MousePhenoenamel pits

AMELX AMELY

2.58e-055232MP:0030460
MousePhenoshort upper incisors

AMELX AMELY

3.87e-056232MP:0030090
MousePhenosmall upper incisors

AMELX AMELY

5.41e-057232MP:0030081
MousePhenoshort lower incisors

AMELX AMELY

5.41e-057232MP:0030089
MousePhenoabnormal facial morphology

SOX5 ETV5 AMELX AMELY NCOA6 COL11A2 BRD4 ESRP1

6.36e-05910238MP:0003743
MousePhenoabnormal enamel rod pattern

AMELX AMELY

7.21e-058232MP:0002649
MousePhenoabnormal tooth wear

AMELX AMELY

1.16e-0410232MP:0030458
MousePhenosmall lower incisors

AMELX AMELY

1.41e-0411232MP:0030080
MousePhenobrittle teeth

AMELX AMELY

1.69e-0412232MP:0000126
MousePhenoreduced enamel thickness

AMELX AMELY

1.69e-0412232MP:0002577
MousePhenocraniofacial phenotype

SOX5 FGD1 ETV5 AMELX AMELY NCOA6 COL11A2 BRD4 ESRP1

1.88e-041372239MP:0005382
MousePhenoabnormal craniofacial morphology

SOX5 FGD1 ETV5 AMELX AMELY NCOA6 COL11A2 BRD4 ESRP1

1.88e-041372239MP:0000428
MousePhenoincreased lung tissue damping

AMELX AMELY

2.00e-0413232MP:0011047
MousePhenoabnormal enamel mineralization

AMELX AMELY

2.00e-0413232MP:0030450
MousePhenoshort incisors

AMELX AMELY

2.33e-0414232MP:0004830
MousePhenoabnormal head morphology

SOX5 ETV5 AMELX AMELY NCOA6 COL11A2 BRD4 ESRP1

2.73e-041120238MP:0000432
MousePhenoabnormal palatal shelf fusion at midline

SOX5 NCOA6 ESRP1

2.94e-0480233MP:0009887
MousePhenoabnormal lung tissue damping

AMELX AMELY

3.06e-0416232MP:0011046
MousePhenoabnormal molar cusp morphology

AMELX AMELY

3.06e-0416232MP:0030457
MousePhenoabnormal incisor color

AMELX AMELY

3.06e-0416232MP:0010096
MousePhenoprenatal growth retardation

FGD1 ANKRD17 NCOA6 TOX4 BRD4 ESRP1 NPAT

3.56e-04869237MP:0010865
MousePhenoabnormal upper incisor morphology

AMELX AMELY

4.35e-0419232MP:0030137
MousePhenoabsent teeth

AMELX AMELY

4.83e-0420232MP:0030610
MousePhenoabnormal craniofacial development

SOX5 AMELX AMELY NCOA6 ESRP1

5.43e-04425235MP:0003935
MousePhenosmall incisors

AMELX AMELY

5.86e-0422232MP:0030079
MousePhenoabnormal molar crown morphology

AMELX AMELY

5.86e-0422232MP:0003932
MousePhenoabnormal ameloblast morphology

AMELX AMELY

5.86e-0422232MP:0002650
MousePhenoabnormal lower incisor morphology

AMELX AMELY

7.59e-0425232MP:0030136
MousePhenoabnormal tooth mineralization

AMELX AMELY

8.22e-0426232MP:0002817
MousePhenomicrodontia

AMELX AMELY

8.22e-0426232MP:0030088
MousePhenoabnormal enamel development

AMELX AMELY

8.86e-0427232MP:0030544
MousePhenoabnormal palatal shelf morphology

SOX5 NCOA6 ESRP1

9.87e-04121233MP:0031460
MousePhenoabnormal secondary palate development

SOX5 NCOA6 ESRP1

1.06e-03124233MP:0009655
MousePhenoembryonic growth retardation

FGD1 ANKRD17 NCOA6 TOX4 BRD4 ESRP1

1.18e-03763236MP:0003984
MousePhenoabnormal palate development

SOX5 NCOA6 ESRP1

1.19e-03129233MP:0009653
MousePhenoenlarged stomach

AMELX AMELY

1.33e-0333232MP:0003883
MousePhenoabnormal axial skeleton morphology

SOX5 AMELX AMELY COL11A2 MAGEL2 BRD4 ESRP1 NPAT

1.60e-031458238MP:0002114
MousePhenoabnormal cranium morphology

SOX5 AMELX AMELY COL11A2 BRD4 ESRP1

1.63e-03813236MP:0000438
MousePhenoabnormal craniofacial bone morphology

SOX5 AMELX AMELY COL11A2 BRD4 ESRP1

1.78e-03827236MP:0002116
MousePhenoabnormal tooth color

AMELX AMELY

1.94e-0340232MP:0013129
MousePhenoabnormal zygomatic bone morphology

AMELX AMELY

2.04e-0341232MP:0005270
MousePhenoabnormal viscerocranium morphology

AMELX AMELY COL11A2 BRD4 ESRP1

2.41e-03593235MP:0005274
MousePhenoabnormal enamel morphology

AMELX AMELY

2.46e-0345232MP:0002576
MousePhenodecreased tooth number

AMELX AMELY

2.56e-0346232MP:0030608
MousePhenotrabecula carnea hypoplasia

ANKRD17 NCOA6

2.56e-0346232MP:0000295
MousePhenoabnormal vertebral arch morphology

AMELX AMELY NPAT

2.79e-03174233MP:0004599
MousePhenoabnormal mandible morphology

AMELX AMELY BRD4

2.89e-03176233MP:0000458
MousePhenoabnormal molar morphology

AMELX AMELY

3.14e-0351232MP:0002689
DomainAmelogenin

AMELX AMELY

1.86e-062262IPR004116
DomainAmelogenin

AMELX AMELY

1.86e-062262SM00818
DomainAmelogenin

AMELX AMELY

1.86e-062262PF02948
DomainHMG_box

SOX5 TOX4

2.46e-0353262PF00505
DomainHMG_BOX_2

SOX5 TOX4

2.55e-0354262PS50118
DomainHMG

SOX5 TOX4

2.55e-0354262SM00398
Domain-

SOX5 TOX4

2.64e-03552621.10.30.10
DomainRRM_1

CPEB2 RBFOX2 ESRP1

2.93e-03208263PF00076
DomainRRM

CPEB2 RBFOX2 ESRP1

3.30e-03217263SM00360
DomainHMG_box_dom

SOX5 TOX4

3.67e-0365262IPR009071
DomainRRM_dom

CPEB2 RBFOX2 ESRP1

3.75e-03227263IPR000504
DomainRRM

CPEB2 RBFOX2 ESRP1

3.89e-03230263PS50102
Domain-

CPEB2 RBFOX2 ESRP1

4.59e-032442633.30.70.330
DomainNucleotide-bd_a/b_plait

CPEB2 RBFOX2 ESRP1

5.36e-03258263IPR012677
DomainCollagen

COL8A1 COL11A2

6.20e-0385262PF01391
DomainCollagen

COL8A1 COL11A2

6.20e-0385262IPR008160
Pubmed

Cloning and regional localization of the mouse faciogenital dysplasia (Fgd1) gene.

FGD1 AMELX AMELY

3.70e-0952638535076
Pubmed

An FGF signaling loop sustains the generation of differentiated progeny from stem cells in mouse incisors.

ETV5 AMELX AMELY

1.06e-071326318077585
Pubmed

Excess NF-κB induces ectopic odontogenesis in embryonic incisor epithelium.

ETV5 AMELX AMELY

1.06e-071326325376721
Pubmed

Isl1 Controls Patterning and Mineralization of Enamel in the Continuously Renewing Mouse Incisor.

ETV5 AMELX AMELY

4.19e-072026328650075
Pubmed

Amelogenin-deficient mice display an amelogenesis imperfecta phenotype.

AMELX AMELY

5.37e-07226211406633
Pubmed

Analysis of self-assembly and apatite binding properties of amelogenin proteins lacking the hydrophilic C-terminal.

AMELX AMELY

5.37e-07226211852235
Pubmed

The receptor activator of nuclear factor-kappa B ligand-mediated osteoclastogenic pathway is elevated in amelogenin-null mice.

AMELX AMELY

5.37e-07226212851394
Pubmed

Amelogenin, the major protein of tooth enamel: a new phylogenetic marker for ordinal mammal relationships.

AMELX AMELY

5.37e-07226218346915
Pubmed

Amelogenin genes and sexual dimorphism of teeth in humans and mice.

AMELX AMELY

5.37e-0722621463023
Pubmed

Amelogenin X impacts age-dependent increase of frequency and number in labial incisor grooves in C57BL/6.

AMELX AMELY

5.37e-07226229337060
Pubmed

Translocation of enamel proteins from inner enamel epithelia to odontoblasts during mouse tooth development.

AMELX AMELY

5.37e-0722628179220
Pubmed

Molecular cloning and DNA sequence of rat amelogenin and a comparative analysis of mammalian amelogenin protein sequence divergence.

AMELX AMELY

5.37e-0722628297387
Pubmed

Thermal denaturation of a recombinant mouse amelogenin: circular dichroism and differential scanning calorimetric studies.

AMELX AMELY

5.37e-07226216284958
Pubmed

Phosphorylation and ionic strength alter the LRAP-HAP interface in the N-terminus.

AMELX AMELY

5.37e-07226223477367
Pubmed

Protein interactions during assembly of the enamel organic extracellular matrix.

AMELX AMELY

5.37e-0722629041053
Pubmed

Highly acidic pH facilitates enamel protein self-assembly, apatite crystal growth and enamel protein interactions in the early enamel matrix.

AMELX AMELY

5.37e-07226236569763
Pubmed

Exon4 amelogenin transcripts in enamel biomineralization.

AMELX AMELY

5.37e-07226225792521
Pubmed

The leucine-rich amelogenin peptide alters the amelogenin null enamel phenotype.

AMELX AMELY

5.37e-07226218701811
Pubmed

Expression of amelogenin in odontoblasts.

AMELX AMELY

5.37e-07226212667550
Pubmed

Human and mouse amelogenin gene loci are on the sex chromosomes.

AMELX AMELY

5.37e-0722622737677
Pubmed

Spatial- and temporal-restricted pattern for amelogenin gene expression during mouse molar tooth organogenesis.

AMELX AMELY

5.37e-0722623253061
Pubmed

A solution NMR investigation into the early events of amelogenin nanosphere self-assembly initiated with sodium chloride or calcium chloride.

AMELX AMELY

5.37e-07226219086270
Pubmed

Molecular structure of the mouse amelogenin genomic DNA.

AMELX AMELY

5.37e-0722628988368
Pubmed

Hierarchical self-assembly of amelogenin and the regulation of biomineralization at the nanoscale.

AMELX AMELY

5.37e-07226221825148
Pubmed

Putative signaling action of amelogenin utilizes the Wnt/beta-catenin pathway.

AMELX AMELY

5.37e-07226219462488
Pubmed

Polypeptides translated from alternatively spliced transcripts of the amelogenin gene, devoid of the exon 6a, b, c region, have specific effects on tooth germ development in culture.

AMELX AMELY

5.37e-07226212489164
Pubmed

Isolation and characterization of a pseudoautosomal region-specific genetic marker in C57BL/6 mice using genomic representational difference analysis.

AMELX AMELY

5.37e-0722628618899
Pubmed

An EMT-driven alternative splicing program occurs in human breast cancer and modulates cellular phenotype.

RBFOX2 ESRP1

5.37e-07226221876675
Pubmed

Amelogenin: a potential regulator of cementum-associated genes.

AMELX AMELY

5.37e-07226214653387
Pubmed

A synthetic, chemically modified ribozyme eliminates amelogenin, the major translation product in developing mouse enamel in vivo.

AMELX AMELY

5.37e-0722627489712
Pubmed

The leucine-rich amelogenin protein (LRAP) is primarily monomeric and unstructured in physiological solution.

AMELX AMELY

5.37e-07226225449314
Pubmed

High-yield recombinant bacterial expression of 13 C-, 15 N-labeled, serine-16 phosphorylated, murine amelogenin using a modified third generation genetic code expansion protocol.

AMELX AMELY

5.37e-07226236585836
Pubmed

Isolation and characterization of a mouse amelogenin expressed in Escherichia coli.

AMELX AMELY

5.37e-0722628062146
Pubmed

A mutation in the mouse Amelx tri-tyrosyl domain results in impaired secretion of amelogenin and phenocopies human X-linked amelogenesis imperfecta.

AMELX AMELY

5.37e-07226220067920
Pubmed

Transgenic mice that express normal and mutated amelogenins.

AMELX AMELY

5.37e-07226217384027
Pubmed

Novel LRAP-binding partner revealing the plasminogen activation system as a regulator of cementoblast differentiation and mineral nodule formation in vitro.

AMELX AMELY

5.37e-07226231621902
Pubmed

Reuptake of extracellular amelogenin by dental epithelial cells results in increased levels of amelogenin mRNA through enhanced mRNA stabilization.

AMELX AMELY

5.37e-07226216293627
Pubmed

Alternative splicing of the mouse amelogenin primary RNA transcript.

AMELX AMELY

5.37e-0722627820782
Pubmed

Controlled Osteogenic Differentiation of Mouse Mesenchymal Stem Cells by Tetracycline-Controlled Transcriptional Activation of Amelogenin.

AMELX AMELY

5.37e-07226226709694
Pubmed

Leucine rich amelogenin peptide alters ameloblast differentiation in vivo.

AMELX AMELY

5.37e-07226223747796
Pubmed

Evolution in tooth developmental biology: of morphology and molecules.

AMELX AMELY

5.37e-0722628769659
Pubmed

Amelogenin promotes odontoblast-like MDPC-23 cell differentiation via activation of ERK1/2 and p38 MAPK.

AMELX AMELY

5.37e-07226221547453
Pubmed

Amelogenin signal peptide mutation: correlation between mutations in the amelogenin gene (AMGX) and manifestations of X-linked amelogenesis imperfecta.

AMELX AMELY

5.37e-0722627782077
Pubmed

Alternative splicing of the mouse amelogenin primary RNA transcript contributes to amelogenin heterogeneity.

AMELX AMELY

5.37e-0722621445358
Pubmed

Altered amelogenin self-assembly based on mutations observed in human X-linked amelogenesis imperfecta (AIH1).

AMELX AMELY

5.37e-07226211877393
Pubmed

Comparison of body weight and gene expression in amelogenin null and wild-type mice.

AMELX AMELY

5.37e-07226216674684
Pubmed

Enamel ribbons, surface nodules, and octacalcium phosphate in C57BL/6 Amelx-/- mice and Amelx+/- lyonization.

AMELX AMELY

5.37e-07226227896287
Pubmed

Amelogenin-collagen interactions regulate calcium phosphate mineralization in vitro.

AMELX AMELY

5.37e-07226220404336
Pubmed

Maintenance of amelogenin gene expression by transformed epithelial cells of mouse enamel organ.

AMELX AMELY

5.37e-0722621444889
Pubmed

Partial rescue of the amelogenin null dental enamel phenotype.

AMELX AMELY

5.37e-07226218390542
Pubmed

Folding, assembly, and aggregation of recombinant murine amelogenins with T21I and P41T point mutations.

AMELX AMELY

5.37e-07226221540557
Pubmed

The energetic basis for hydroxyapatite mineralization by amelogenin variants provides insights into the origin of amelogenesis imperfecta.

AMELX AMELY

5.37e-07226231239344
Pubmed

Amelogenin in cranio-facial development: the tooth as a model to study the role of amelogenin during embryogenesis.

AMELX AMELY

5.37e-07226219097165
Pubmed

Identification of the functional activity of the [A-4] amelogenin gene splice product in newborn mouse ameloblasts.

AMELX AMELY

5.37e-07226218394981
Pubmed

A solution NMR investigation into the murine amelogenin splice-variant LRAP (Leucine-Rich Amelogenin Protein).

AMELX AMELY

5.37e-07226220304108
Pubmed

Endoplasmic reticulum stress in amelogenesis imperfecta and phenotypic rescue using 4-phenylbutyrate.

AMELX AMELY

5.37e-07226224362885
Pubmed

A solution NMR investigation into the impaired self-assembly properties of two murine amelogenins containing the point mutations T21→I or P41→T.

AMELX AMELY

5.37e-07226223896516
Pubmed

Two related low molecular mass polypeptide isoforms of amelogenin have distinct activities in mouse tooth germ differentiation in vitro.

AMELX AMELY

5.37e-07226215647828
Pubmed

DNA sequence for cloned cDNA for murine amelogenin reveal the amino acid sequence for enamel-specific protein.

AMELX AMELY

5.37e-0722624015654
Pubmed

Stage-Specific Role of Amelx Activation in Stepwise Ameloblast Induction from Mouse Induced Pluripotent Stem Cells.

AMELX AMELY

5.37e-07226234281250
Pubmed

The X-Y homologous gene amelogenin maps to the short arms of both the X and Y chromosomes and is highly conserved in primates.

AMELX AMELY

5.37e-0722621427830
Pubmed

Weaker dental enamel explains dental decay.

AMELX AMELY

5.37e-07226225885796
Pubmed

Transgene animal model for protein expression and accumulation into forming enamel.

AMELX AMELY

5.37e-07226211063035
Pubmed

Regulation of amelogenin gene expression.

AMELX AMELY

5.37e-07226210200911
Pubmed

Structural variation of the pseudoautosomal region between and within inbred mouse strains.

AMELX AMELY

5.37e-0722628552598
Pubmed

Truncated amelogenin and LRAP transgenes improve Amelx null mouse enamel.

AMELX AMELY

5.37e-07226226607574
Pubmed

A human X-Y homologous region encodes "amelogenin".

AMELX AMELY

5.37e-0722622004775
Pubmed

Loss of biological control of enamel mineralization in amelogenin-phosphorylation-deficient mice.

AMELX AMELY

5.37e-07226235219810
Pubmed

Of mice and men: anatomy of the amelogenin gene.

AMELX AMELY

5.37e-0722622689082
Pubmed

Altering biomineralization by protein design.

AMELX AMELY

5.37e-07226216707492
Pubmed

The amelogenin C-terminus is required for enamel development.

AMELX AMELY

5.37e-07226220042744
Pubmed

Amelogenin supramolecular assembly in nanospheres defined by a complex helix-coil-PPII helix 3D-structure.

AMELX AMELY

5.37e-07226221984897
Pubmed

Leucine rich amelogenin peptide prevents ovariectomy-induced bone loss in mice.

AMELX AMELY

5.37e-07226234780561
Pubmed

The murine amelogenin promoter: developmentally regulated expression in transgenic animals.

AMELX AMELY

5.37e-0722629084642
Pubmed

Comparison of upstream regions of X- and Y-chromosomal amelogenin genes.

AMELX AMELY

5.37e-0722629714776
Pubmed

Cryogenic transmission electron microscopy study of amelogenin self-assembly at different pH.

AMELX AMELY

5.37e-07226221597263
Pubmed

Characterization of copy number variation in genomic regions containing STR loci using array comparative genomic hybridization.

AMELX AMELY

5.37e-07226223948316
Pubmed

Antisense inhibition of AMEL translation demonstrates supramolecular controls for enamel HAP crystal growth during embryonic mouse molar development.

AMELX AMELY

5.37e-0722628392462
Pubmed

Amelogenin phosphorylation regulates tooth enamel formation by stabilizing a transient amorphous mineral precursor.

AMELX AMELY

5.37e-07226231919099
Pubmed

The small bovine amelogenin LRAP fails to rescue the amelogenin null phenotype.

AMELX AMELY

5.37e-07226212958690
Pubmed

[Types and frequencies of variants in Amelogenin gene in Chinese population].

AMELX AMELY

5.37e-07226218067069
Pubmed

Amelogenins as potential buffers during secretory-stage amelogenesis.

AMELX AMELY

5.37e-07226225535204
Pubmed

The circadian clock modulates enamel development.

AMELX AMELY

5.37e-07226222653892
Pubmed

An amelogenin mutation leads to disruption of the odontogenic apparatus and aberrant expression of Notch1.

AMELX AMELY

5.37e-07226220923441
Pubmed

Cloning, characterization, and heterologous expression of exon-4-containing amelogenin mRNAs.

AMELX AMELY

5.37e-0722629062557
Pubmed

Model system for evaluation of alternative splicing: exon skipping.

AMELX AMELY

5.37e-07226211879574
Pubmed

Patchy fur, a mouse coat mutation associated with X-Y nondisjunction, maps to the pseudoautosomal boundary region.

AMELX AMELY

5.37e-0722629878259
Pubmed

Mouse amelogenin exons 8 and 9: sequence analysis and protein distribution.

AMELX AMELY

5.37e-07226215972588
Pubmed

Early evolution of enamel matrix proteins is reflected by pleiotropy of physiological functions.

AMELX AMELY

1.61e-06326236702824
Pubmed

Origin, splicing, and expression of rodent amelogenin exon 8.

AMELX AMELY

1.61e-06326216998127
Pubmed

Early determination and permissive expression of amelogenin transcription during mouse mandibular first molar development.

AMELX AMELY

1.61e-0632628026631
Pubmed

Amelogenin binds to both heparan sulfate and bone morphogenetic protein 2 and pharmacologically suppresses the effect of noggin.

AMELX AMELY

1.61e-06326218515207
Pubmed

Expression and function of enamel-related gene products in calvarial development.

AMELX AMELY

1.61e-06326223625374
Pubmed

Alternative splicing of amelogenins.

AMELX AMELY

1.61e-0632627554909
Pubmed

Amyloid structure of high-order assembly of Leucine-rich amelogenin revealed by solid-state NMR.

AMELX AMELY

1.61e-06326229604451
Pubmed

Synergistic roles of amelogenin and ameloblastin.

AMELX AMELY

1.61e-06326219407150
Pubmed

The human enamel protein gene amelogenin is expressed from both the X and the Y chromosomes.

AMELX AMELY

1.61e-0632621734713
Pubmed

Tracking endogenous amelogenin and ameloblastin in vivo.

AMELX AMELY

1.61e-06326224933156
Pubmed

MMP20-generated amelogenin cleavage products prevent formation of fan-shaped enamel malformations.

AMELX AMELY

1.61e-06326234012043
Pubmed

GD3 synthase gene found expressed in dental epithelium and shown to regulate cell proliferation.

AMELX AMELY

1.61e-06326215748692
InteractionPRRC2A interactions

SOX5 ANKRD17 COL8A1 GARRE1 BRD4 RBFOX2

6.46e-06389256int:PRRC2A
InteractionUNK interactions

ANKRD17 ARHGAP5 SMG8 GARRE1 RBFOX2 NPAT

8.48e-06408256int:UNK
InteractionYTHDF3 interactions

ANKRD17 SMG8 GARRE1 RBFOX2 PML

1.13e-05246255int:YTHDF3
InteractionMAMLD1 interactions

PML MAMLD1

1.47e-055252int:MAMLD1
InteractionLSM14A interactions

SOX5 ANKRD17 SMG8 COL8A1 GARRE1

1.48e-05260255int:LSM14A
InteractionSF1 interactions

NCOA1 NCOA6 BRD4 RBFOX2 PML

3.13e-05304255int:SF1
InteractionYTHDF2 interactions

ANKRD17 SMG8 MAGEL2 GARRE1 PML

3.55e-05312255int:YTHDF2
InteractionRXRA interactions

NCOA1 NCOA6 BRD4 PML

5.26e-05169254int:RXRA
InteractionZHX2 interactions

SOX5 BRD4 PML

8.37e-0569253int:ZHX2
InteractionPHIP interactions

ANKRD17 GARRE1 BRD4 PML

9.54e-05197254int:PHIP
InteractionTRIM24 interactions

SOX5 NCOA1 ANKRD17 GARRE1 PML

1.12e-04398255int:TRIM24
InteractionNNMT interactions

BRD4 PML

1.33e-0414252int:NNMT
InteractionPPARGC1A interactions

NCOA1 NCOA6 PML

1.40e-0482253int:PPARGC1A
InteractionMEX3B interactions

CPEB2 ANKRD17 SMG8 GARRE1

1.51e-04222254int:MEX3B
InteractionMEN1 interactions

ANKRD17 ARHGAP5 NCOA6 COL8A1 TOX4 DROSHA ESRP1

1.89e-041029257int:MEN1
InteractionPPARA interactions

NCOA1 NCOA6 COL8A1

1.97e-0492253int:PPARA
InteractionCTTN interactions

FGD1 TOX4 MAGEL2 BRD4 PML

1.99e-04450255int:CTTN
InteractionPCNP interactions

BRD4 RBFOX2 PML

2.23e-0496253int:PCNP
InteractionHELZ interactions

ANKRD17 GARRE1 RBFOX2 ESRP1

2.65e-04257254int:HELZ
InteractionYWHAH interactions

NCOA1 ANKRD17 MAGI3 NCOA6 GARRE1 WNK2 BRD4

2.89e-041102257int:YWHAH
InteractionNCOR2 interactions

SOX5 NCOA6 BRD4 PML

2.93e-04264254int:NCOR2
InteractionRCOR1 interactions

SOX5 ANKRD17 TOX4 BRD4 NPAT

3.07e-04494255int:RCOR1
InteractionRBM12 interactions

BRD4 RBFOX2 PML

3.33e-04110253int:RBM12
InteractionTHRA interactions

NCOA1 NCOA6 PML

3.42e-04111253int:THRA
InteractionINTS7 interactions

FGD1 BRD4 PML

3.61e-04113253int:INTS7
InteractionTNRC6A interactions

ANKRD17 NCOA6 GARRE1 RBFOX2

3.67e-04280254int:TNRC6A
InteractionGPATCH8 interactions

BRD4 RBFOX2 ESRP1

3.80e-04115253int:GPATCH8
InteractionMED16 interactions

BRD4 RBFOX2 PML

4.30e-04120253int:MED16
InteractionMAGED1 interactions

SOX5 GARRE1 RBFOX2 PML

4.46e-04295254int:MAGED1
InteractionUBAP2L interactions

ANKRD17 MAGEL2 GARRE1 PML

4.64e-04298254int:UBAP2L
InteractionIGLL5 interactions

FNDC1 BRD4 PML

4.74e-04124253int:IGLL5
InteractionBCOR interactions

SOX5 BRD4 RBFOX2 PML

4.88e-04302254int:BCOR
InteractionRUNX2 interactions

NCOA1 BRD4 PML

4.96e-04126253int:RUNX2
InteractionKMT2B interactions

NCOA6 DROSHA PML

5.44e-04130253int:KMT2B
InteractionFOS interactions

NCOA1 ANKRD17 NCOA6 PML

5.51e-04312254int:FOS
InteractionMED15 interactions

NCOA6 BRD4 PML

5.56e-04131253int:MED15
InteractionSMG7 interactions

NCOA1 ANKRD17 NCOA6 GARRE1

5.99e-04319254int:SMG7
InteractionPOU5F1 interactions

SOX5 ANKRD17 TOX4 BRD4 PML

6.60e-04584255int:POU5F1
InteractionSRF interactions

NCOA1 NCOA6 PML

6.61e-04139253int:SRF
InteractionOBI1 interactions

ANKRD17 GARRE1 BRD4

6.61e-04139253int:OBI1
InteractionQRICH1 interactions

TOX4 BRD4 PML

6.75e-04140253int:QRICH1
InteractionEEF2 interactions

CPEB2 ANKRD17 MAGEL2 BRD4 PML

6.80e-04588255int:EEF2
InteractionGTF2B interactions

NCOA1 BRD4 PML

6.89e-04141253int:GTF2B
InteractionNCOA2 interactions

NCOA1 NCOA6 PML

6.89e-04141253int:NCOA2
InteractionNR1H4 interactions

NCOA1 NCOA6

7.16e-0432252int:NR1H4
InteractionGTF2F2 interactions

COL8A1 BRD4 PML

7.18e-04143253int:GTF2F2
GeneFamilyCollagens

COL8A1 COL11A2

6.51e-0446152490
GeneFamilyRNA binding motif containing

CPEB2 RBFOX2 ESRP1

6.61e-04213153725
CoexpressionNABA_CORE_MATRISOME

AMELX AMELY COL8A1 FNDC1 COL11A2

6.16e-06270265MM17057
CoexpressionNABA_CORE_MATRISOME

AMELX AMELY COL8A1 FNDC1 COL11A2

6.73e-06275265M5884
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

NCOA1 ANKRD17 COL8A1 GARRE1 RBFOX2 MAMLD1 NPAT

1.48e-05856267M4500
CoexpressionSHEN_SMARCA2_TARGETS_UP

NCOA1 ANKRD17 ARHGAP5 NCOA6 GARRE1

5.68e-05429265M29
CoexpressionNABA_MATRISOME_HIGHLY_METASTATIC_MELANOMA_TUMOR_CELL_DERIVED

COL8A1 COL11A2

6.21e-0512262M47983
CoexpressionAtlasFacebaseRNAseq_e9.5_Facial Mesenchyne_top-relative-expression-ranked_1000_k-means-cluster#4

NCOA1 COL8A1 WNK2 MAMLD1

1.26e-04223254Facebase_RNAseq_e9.5_Facial Mesenchyne_1000_K4
CoexpressionAtlasFacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_1000_k-means-cluster#4

NCOA1 COL8A1 WNK2 MAMLD1

1.47e-04232254Facebase_RNAseq_e9.5_Maxillary Arch_1000_K4
CoexpressionAtlasFacebaseRNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_1000_k-means-cluster#1

NCOA1 COL8A1 WNK2 MAMLD1

1.49e-04233254Facebase_RNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_1000_K1
CoexpressionAtlasFacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_1000_k-means-cluster#4

NCOA1 COL8A1 WNK2 MAMLD1

1.86e-04247254Facebase_RNAseq_e8.5_Paraxial Mesoderm_1000_K4
CoexpressionAtlasFacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_1000_k-means-cluster#2

NCOA1 COL8A1 WNK2 MAMLD1

1.92e-04249254Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_1000_K2
CoexpressionAtlasDevelopingGonad_e14.5_ ovary_emap-6699_top-relative-expression-ranked_1000

CPEB2 SOX5 ANKRD17 ARHGAP5 GARRE1 NPAT

2.28e-04776256gudmap_developingGonad_e14.5_ ovary_1000
ToppCellAdult-Epithelial|Adult / Lineage, Cell type, age group and donor

SOX5 MAGI3 COL8A1 RBFOX2 ESRP1

8.22e-08192265efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCellfacs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l34|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SOX5 ETV5 COL8A1 COL11A2

3.16e-0617626477c3da2eaa072a6baefb5087fd07ec18c5e271cd
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma-7|TCGA-Colorectal / Sample_Type by Project: Shred V9

NCOA6 COL8A1 FNDC1 GARRE1

3.31e-06178264edc76b8f15056ec1c9a1c61a048b6331a92592d6
ToppCellwk_08-11-Mesenchymal-Chondrocyte-Resting_chondrocyte|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

SOX5 COL8A1 COL11A2 WNK2

3.61e-0618226400a148b1e499bf16325491536d187d4dd6b70c06
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX5 ETV5 FNDC1 COL11A2

4.11e-06188264006db2c2c44971ca9241c582bc89f258c785f5ed
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-7|TCGA-Colorectal / Sample_Type by Project: Shred V9

NCOA6 COL8A1 FNDC1 GARRE1

4.11e-0618826414bc73cf79c79c9f208369fd8d498e5b26e0114d
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX5 ETV5 FNDC1 COL11A2

4.11e-06188264d0e6fb4a3b3d79d3512b5500062ea285495ae526
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SOX5 ETV5 MAGI3 ESRP1

4.28e-061902648aea807a2bcf0b653b4de6202b6ecb0f0683cc2e
ToppCell10x5'v1-week_17-19-Mesenchymal_myocytic-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

FGD1 FNDC1 COL11A2 RBFOX2

4.28e-0619026481f8f2cddf4c51b879f315260cd1fca80355a371
ToppCell10x5'v1-week_17-19-Mesenchymal_myocytic|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

FGD1 FNDC1 COL11A2 RBFOX2

4.28e-06190264877b544decf302e0d41be23dffa1861f79c70914
ToppCell10x5'v1-week_17-19-Mesenchymal_myocytic-stroma-muscle|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

FGD1 FNDC1 COL11A2 RBFOX2

4.28e-0619026420106e5213f6a7560554b8b4f84b23c5554ba975
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2|Children_(3_yrs) / Lineage, Cell type, age group and donor

SOX5 ETV5 MAGI3 ESRP1

4.37e-06191264a0332a4ef629510fb313ec119195c44a3f704a80
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SOX5 ETV5 MAGI3 ESRP1

4.37e-0619126434cc997e4e5c727495f321e6807a84aa124da486
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SOX5 ETV5 MAGI3 ESRP1

4.46e-06192264fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCellEpithelial|World / Lineage, Cell type, age group and donor

SOX5 MAGI3 COL8A1 ESRP1

4.46e-06192264499e8893afea5e6d3371e0bd018f7e86a524d669
ToppCellEpithelial-alveolar_epithelial_cell_type_2|World / Lineage, Cell type, age group and donor

SOX5 ETV5 MAGI3 ESRP1

4.46e-0619226458c3737be7acce39fd2b91d70d6d7b2bbaa4f710
ToppCellnucseq-Epithelial|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SOX5 MAGI3 COL8A1 ESRP1

4.75e-061952649406866f99555198a9be311fbd65751b70f35446
ToppCellBronchial-NucSeq|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations

SOX5 NCOA1 MAGI3 RBFOX2

4.84e-06196264ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l34|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SOX5 ETV5 COL8A1 COL11A2

4.94e-061972646e111ba16fc8adde782b3f7da250248cddf11228
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SOX5 ETV5 COL8A1 COL11A2

4.94e-061972644b6c0e028b9669c102df8e9dc63e284f8d5fd9ee
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SOX5 ETV5 COL8A1 COL11A2

4.94e-06197264ece0c17eb68f394b20e588c0b0626d3987a4dbbb
ToppCellfacs-Trachea-nan-3m-Mesenchymal-chondrocyte|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX5 ETV5 COL8A1 COL11A2

5.04e-0619826471e847e8c24744d6df4a960348ad2ecf310373b4
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

SOX5 NCOA1 MAGI3 RBFOX2

5.04e-061982641996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell18-Airway-Mesenchymal-Cartilage|Airway / Age, Tissue, Lineage and Cell class

SOX5 COL8A1 FNDC1 COL11A2

5.14e-06199264f5d0aa4170367c080d3c2f01d9af3529762917fa
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

SOX5 NCOA1 MAGI3 RBFOX2

5.14e-0619926494b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell356C-Fibroblasts-Fibroblast-C_(Myofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

SMG8 MAGEL2 DROSHA

7.59e-051422637b6678a73d04feac12bbc909f2df478215511de0
ToppCell356C-Fibroblasts-Fibroblast-C_(Myofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

SMG8 MAGEL2 DROSHA

7.59e-05142263347f5832a86f4e41752e36e3e737df7ca6f79e90
ToppCellChildren_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

SOX5 FNDC1 MAMLD1

9.47e-051532631524557514668f515ac1bbe847611f564b265b42
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ETV5 COL8A1 TOX4

1.14e-0416326363b0badaee3b2d827b1f4524510e3384d8f8fcde
ToppCell3'-GW_trimst-1-SmallIntestine-Epithelial-epithelial_progenitor_cell-Distal_progenitor|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL11A2 WNK2 ESRP1

1.16e-04164263ea02ca343b2b28e437304de889e2ae1e315a1197
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte-Chondrocyte_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SOX5 COL8A1 COL11A2

1.20e-0416626337794a84601a2a949d579663d4a4bb8bc8fb5923
ToppCellNS-critical-d_0-4-Epithelial-unknown_epithelial|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SOX5 NCOA6 RBFOX2

1.20e-04166263dd02bbe4af609c6348dc92417254f4740f2900a8
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SOX5 COL8A1 COL11A2

1.20e-0416626381c546c6d847e49e662b81e71992ca0f7a99e890
ToppCellfacs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l34|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SOX5 COL8A1 COL11A2

1.23e-04167263102b3d160a44c8623fab1fd10e9054178c42a78b
ToppCellE17.5-Mesenchymal-mesenchymal_fibroblast-tracheal_fibroblast|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SOX5 COL8A1 COL11A2

1.27e-0416926358e22f9119240664515fe91ca53812611a8f17d6
ToppCellAT1-AT2_cells-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

ARHGAP5 MAGI3 COL8A1

1.27e-04169263815474855a70498a74e52f6583113c63b7267a0c
ToppCellwk_20-22-Mesenchymal-Chondrocyte|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

SOX5 COL8A1 COL11A2

1.32e-04171263d2938639e9a7c349e5a6ec61724222f9d127c89f
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

ETV5 COL8A1 TOX4

1.34e-04172263da959c1abadafd79b7a0088a25eb8ef8efa3a0c2
ToppCellmetastatic_Brain-Endothelial_cells-Stalk-like_ECs|Endothelial_cells / Location, Cell class and cell subclass

SMG8 COL8A1 MAMLD1

1.41e-04175263f6a6db992e803d36c866a91706b02f67e0fd3e09
ToppCellP15-Mesenchymal-mesenchymal_fibroblast-tracheal_fibroblast|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SOX5 COL8A1 COL11A2

1.41e-04175263085cceb1fc2c4ae2f27e85cea5702defecc2cf44
ToppCellwk_15-18-Mesenchymal-Chondrocyte-ASPN+_chondrocyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

COL8A1 FNDC1 COL11A2

1.48e-04178263a55130670aa95a87b833dd3cd2de461d779e4c06
ToppCellP03-Mesenchymal-mesenchymal_fibroblast-tracheal_fibroblast|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SOX5 COL8A1 COL11A2

1.48e-041782638591a40fced747ac16b3e8ebc7a22dfb3ad76da2
ToppCellCOVID-19-Epithelial_cells-AT1|COVID-19 / group, cell type (main and fine annotations)

MAGI3 COL8A1 ESRP1

1.51e-04179263a0b33bd69ffdfd5d38d80207fb40058a490aa19e
ToppCellControl-Epithelial_cells-AT2|Control / group, cell type (main and fine annotations)

SOX5 ETV5 MAGI3

1.53e-04180263198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCellwk_20-22-Mesenchymal-Chondrocyte-Resting_chondrocyte|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

SOX5 COL8A1 COL11A2

1.58e-0418226303a5a02acd48f0eb210485348bfe0cd21f486215
ToppCellCOVID-19-lung-AT1|COVID-19 / Disease (COVID-19 only), tissue and cell type

MAGI3 COL8A1 ESRP1

1.61e-041832637b1a385ed54f93bfe85bf0c162e42d05d516b45c
ToppCellAT1-AT2_cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

MAGI3 COL8A1 FNDC1

1.61e-041832636821dca076318115d360ff426eb1218cfe104063
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 COL8A1 MAMLD1

1.63e-04184263c5436a8e45f471b8d1301abbe9c7879204537f52
ToppCellFetal_29-31_weeks-Mesenchymal-chondrocyte-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SOX5 FNDC1 COL11A2

1.66e-041852638ed10ba581849c9c4ac4397226be2b62b4b3b900
ToppCellCOVID-19-Epithelial_cells-Airway_club|COVID-19 / group, cell type (main and fine annotations)

MAGI3 WNK2 ESRP1

1.66e-04185263cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCellControl-Epithelial_alveolar-AT_2-Differentiating_AT2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ETV5 MAGI3 ESRP1

1.66e-041852630d2add28ac1f4fa6de7699be009bf8391badaf4c
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SOX5 MAGI3 ESRP1

1.69e-041862632ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCell10x5'v1-week_12-13-Mesenchymal_osteo-stroma-chondrocyte|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

COL8A1 COL11A2 MAGEL2

1.74e-04188263c9270517e6940e9793586f67f02431210552f278
ToppCellControl-Epithelial_cells|Control / group, cell type (main and fine annotations)

SOX5 MAGI3 COL8A1

1.74e-04188263707ebf76cc6fb600b2f07793cf4ea9482c0de79d
ToppCellCOPD-Epithelial-ATII|COPD / Disease state, Lineage and Cell class

SOX5 ETV5 COL8A1

1.74e-04188263eb6d79d733b53f64ca615bb777c64ed456866549
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 COL8A1 FNDC1

1.79e-0419026370c86dd454afb21d4a85db56c5f369d4b342bc97
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 COL8A1 FNDC1

1.82e-0419126339092a0aff8097617820c59f5fea9ee2bb4f63a2
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 COL8A1 FNDC1

1.82e-04191263bc353a79a1d11ca52bba5e3874a80d432e1a7715
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 COL8A1 FNDC1

1.82e-04191263107113b930d9ad171f1b2aa20df4567c94fae7d8
ToppCellfacs-Aorta-Heart-3m-Mesenchymal-leukocyte|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX5 COL11A2 ESRP1

1.82e-04191263116fba9badea093e11f370996247cca0e4c02e8f
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SOX5 MAGI3 ESRP1

1.82e-04191263ca5669bd6f4a17471acae3eb229f845cc2e08efa
ToppCellIPF-Epithelial-Club|World / Disease state, Lineage and Cell class

SOX5 MAGI3 ESRP1

1.82e-041912633c88a6f1d74bb3b9173cd0ea3a63c6d9570e3954
ToppCellmetastatic_Lymph_Node-Fibroblasts-Myofibroblasts|metastatic_Lymph_Node / Location, Cell class and cell subclass

COL8A1 FNDC1 MAGEL2

1.82e-04191263aa43b472bc8362f79ae63f09f1ca764718bbf22c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 COL8A1 FNDC1

1.82e-04191263ee5f1b1c59029c46cbb1a00935c03b9317bb9da9
ToppCellChildren_(3_yrs)-Epithelial|Children_(3_yrs) / Lineage, Cell type, age group and donor

SOX5 MAGI3 ESRP1

1.82e-04191263e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCellCOPD-Epithelial-Goblet|COPD / Disease state, Lineage and Cell class

SOX5 WNK2 ESRP1

1.85e-0419226393b2ca0a97776d28c7e8f1a0642c4b63a5554aab
ToppCellCOVID-19-lung-Secretory|COVID-19 / Disease (COVID-19 only), tissue and cell type

MAGI3 WNK2 ESRP1

1.85e-0419226359261098ccb52306f837f632ebaea45b90ad30fe
ToppCellEpithelial-club_cell|World / Lineage, Cell type, age group and donor

MAGI3 WNK2 ESRP1

1.88e-041932632bdd09004fa433550958ec42ba4b06271a4aaf7c
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SOX5 ETV5 MAGI3

1.88e-04193263f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCellFetal_29-31_weeks-Epithelial|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SOX5 MAGI3 ESRP1

1.88e-04193263a0ca3231992f14abcf1a6129573bace320e89d2a
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SOX5 ETV5 MAGI3

1.88e-04193263fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCell11.5-Airway-Mesenchymal-Cartilage|Airway / Age, Tissue, Lineage and Cell class

SOX5 FNDC1 COL11A2

1.88e-04193263d4779d92a4dd4b8b656383e6f4fce76d3bd70931
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-10|TCGA-Colorectal / Sample_Type by Project: Shred V9

COL8A1 FNDC1 MAGEL2

1.88e-04193263194e7fa00a50cc4e026987b715323d125d79594e
ToppCellCOVID-19-Fibroblasts-Other_FB|COVID-19 / group, cell type (main and fine annotations)

SOX5 COL8A1 RBFOX2

1.88e-04193263e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCellnucseq-Epithelial-Epithelial_Alveolar|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SOX5 MAGI3 COL8A1

1.91e-0419426353f3e49e91b1096f3226010e2de767efb490dfe4
ToppCelldroplet-Limb_Muscle-MUSCLE|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP5 COL11A2 GARRE1

1.91e-04194263e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 COL8A1 FNDC1

1.94e-04195263dd281a249854800f737dc22e0f375f66dfb5cf5f
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

MAGI3 WNK2 ESRP1

1.94e-04195263dccc32fcf772e2504de7f663ef0a5bd8e23e92fc
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 COL8A1 FNDC1

1.94e-0419526349c99553629cdd83ee56a2e508d5bc8d34b8507b
ToppCell15-Airway-Mesenchymal-Cartilage|Airway / Age, Tissue, Lineage and Cell class

SOX5 FNDC1 COL11A2

1.94e-04195263414f60bc0f0d0ecb5137bcd617fae91f0c15038a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 COL8A1 FNDC1

1.97e-04196263802f61e78a9a1030a86c4a980c398a73cd4d1574
ToppCell10x5'v1-week_17-19-Mesenchymal_osteo-stroma-osteoblast_precursor|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

COL8A1 FNDC1 RBFOX2

1.97e-0419626357df2a57b35be9851ac0b1e5731baa53052511f0
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 COL8A1 FNDC1

1.97e-04196263fa445f4240c521cf04eb2e2f79a5c55fda31209a
ToppCell(3)_Chondrocytes-(30)_Chondro|World / Cell class and subclass of bone marrow stroma cells in homeostatis

SOX5 COL11A2 WNK2

2.00e-04197263a07ab2564ca7d577fd47f444dd7b0c25556e9fc4
ToppCelldroplet-Trachea-nan-3m-Mesenchymal-chondrocyte|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX5 COL8A1 COL11A2

2.00e-041972638786125b669d5d0b15e12df0ade6b319f09f7333
ToppCellwk_08-11-Epithelial-Airway_epithelial_progenitor-epi-airway_progenitor_early|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

SOX5 MAGI3 ESRP1

2.00e-041972634ae08ccb6f1da626c4f0fb0140a2811cb6e31ba1
ToppCell10x5'v1-week_12-13-Mesenchymal_osteo-stroma-osteoblast_precursor|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

SOX5 COL8A1 FNDC1

2.00e-041972632f72fd9a5b6d62c24a95ed2246194ea7458c0f12
ToppCellASK428-Epithelial-Type_1|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

ARHGAP5 MAGI3 COL8A1

2.00e-041972639ae6661c307791c3f0ecd3d378e3d917565e5498
ToppCellBAL-Severe-Epithelial-Epithelial-AT1/AT2-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

COL8A1 RBFOX2 ESRP1

2.03e-0419826333d1e0b6f57663544bee0ffdde83a65da764d44c
ToppCellwk_15-18-Epithelial-Airway_epithelial_progenitor-epi-stalk_late|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ETV5 MAGI3 ESRP1

2.03e-041982631851b7f4198b42c21c934e2fbda39dbd65e2625c
ToppCellSevere_COVID-19-Epithelial-AT1/AT2|Severe_COVID-19 / Disease group,lineage and cell class (2021.01.30)

COL8A1 RBFOX2 ESRP1

2.03e-0419826343e33d28d9de5033bd00d39be953542a225236ed
ToppCellCOVID-19-Epithelial-AT2,_AT1_cells|COVID-19 / Condition, Lineage and Cell class

COL8A1 RBFOX2 ESRP1

2.03e-041982637e6f089e71e70190ff8486341ab06719d7741467
ToppCellFibroblasts-HLA-DRA_high_Fibroblasts|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

COL8A1 FNDC1 RBFOX2

2.03e-04198263e8c0fbf306fae13e97caa294d7c99a564bd97130
ToppCellFetal_29-31_weeks-Epithelial-club_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MAGI3 WNK2 ESRP1

2.03e-041982636ba5e5970109a04ed968bac7ff099ae250c579dc
ToppCell10x3'2.3-week_14-16-Mesenchymal_osteo-stroma-osteoblast_precursor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

COL8A1 FNDC1 RBFOX2

2.03e-041982639d61483b0decac2fe90045b3474843360b2c49b3
ToppCelldroplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l34|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SOX5 COL8A1 COL11A2

2.03e-041982633575620db5aeaeb0bdcd7a8ff65c43abd3fa13e4
ToppCellFetal_29-31_weeks-Epithelial-club_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MAGI3 WNK2 ESRP1

2.03e-041982635fc25b008a4d8d6bec83923a16f64dd9e1ff1f2d
ToppCellBAL-Severe-Epithelial-Epithelial-AT1/AT2|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

COL8A1 RBFOX2 ESRP1

2.03e-04198263aed0476248e9637897eefb1623ec4035f2dacd82
ToppCellBAL-Severe-Epithelial-Epithelial-AT1/AT2-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

COL8A1 RBFOX2 ESRP1

2.03e-04198263691a2f1779225e5519155460eeb6a2aac5f67a92
ToppCellBAL-Severe-Epithelial-Epithelial-AT1/AT2|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

COL8A1 RBFOX2 ESRP1

2.03e-04198263e115eea04012e9e492e923ed080e1723c38d14fd
Drugcalcium phosphate

AMELX AMELY NCOA6 COL11A2 RBFOX2

6.61e-07149265CID000024441
DrugHBGG

AMELX AMELY NCOA6

2.01e-0622263CID000125044
DrugDiprophylline [479-18-5]; Up 200; 15.8uM; HL60; HT_HG-U133A

ETV5 GARRE1 BRD4 RBFOX2 PML

2.62e-061972651853_UP
Drugganoine

AMELX AMELY

3.76e-063262CID000131592
Drugleu-leu

AMELX AMELY RBFOX2

5.26e-0630263CID000076807
Drugandrostan-3-ol

NCOA1 NCOA6

1.88e-056262ctd:C000658
DrugTrifluridine [70-00-8]; Up 200; 13.6uM; MCF7; HT_HG-U133A

FGD1 ETV5 RBFOX2 PML

5.84e-051882643559_UP
Drugtrichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A

ARHGAP5 NCOA6 RBFOX2 ESRP1

6.21e-051912647503_DN
DrugClioquinol [130-26-7]; Up 200; 13uM; MCF7; HT_HG-U133A

FGD1 AMELX COL8A1 PML

6.21e-051912646461_UP
Drug5155877; Up 200; 10uM; MCF7; HT_HG-U133A

NCOA1 GARRE1 MAMLD1 NPAT

6.34e-051922646574_UP
DrugAspartic acid, N-acetyl (R,S) [997-55-7]; Up 200; 22.8uM; MCF7; HT_HG-U133A

FGD1 ETV5 AMELY COL8A1

6.47e-051932644125_UP
DrugST021200; Down 200; 10uM; PC3; HT_HG-U133A

TOX4 GARRE1 RBFOX2 PML

6.73e-051952647493_DN
DrugNafronyl oxalate [3200-06-4]; Down 200; 8.4uM; HL60; HT_HG-U133A

NCOA1 RBFOX2 PML NPAT

6.73e-051952641267_DN
Drugmoenomycin

AMELX NCOA6

6.85e-0511262CID006433554
DrugAmpF

AMELX AMELY

6.85e-0511262CID000193541
DrugTelenzepine dihydrochloride [147416-96-4]; Down 200; 9uM; HL60; HT_HG-U133A

NCOA1 BRD4 RBFOX2 PML

6.86e-051962642388_DN
Drug16, 16-dimethylprostaglandin E2 methyl acetate solution; Down 200; 10uM; MCF7; HT_HG-U133A

TOX4 RBFOX2 PML NPAT

7.00e-051972646597_DN
DrugPraziquantel [55268-74-1]; Up 200; 12.8uM; MCF7; HT_HG-U133A

ETV5 COL8A1 GARRE1 PML

7.00e-051972647228_UP
DrugChlorogenic acid [327-97-9]; Down 200; 11.2uM; HL60; HT_HG-U133A

NCOA1 TOX4 RBFOX2 PML

7.14e-051982641346_DN
DrugAdiphenine hydrochloride [50-42-0]; Down 200; 11.4uM; PC3; HT_HG-U133A

FGD1 TOX4 RBFOX2 NPAT

7.14e-051982641831_DN
DrugLeflunomide [75706-12-6]; Down 200; 14.8uM; HL60; HT_HG-U133A

TOX4 BRD4 RBFOX2 PML

7.28e-051992642539_DN
DrugEthynylestradiol 3-methyl ether [72-33-3]; Down 200; 12.8uM; HL60; HT_HG-U133A

COL8A1 BRD4 RBFOX2 PML

7.42e-052002643008_DN
DrugAC1L2XIZ

AMELX BRD4

8.22e-0512262CID000104803
Drugleucomalachite green

AMELX AMELY

8.22e-0512262CID000067215
Drugamido black

AMELX AMELY

9.71e-0513262CID005473482
Drugmelarsoprol

COL11A2 PML

1.49e-0416262CID000010311
DrugMikamycine

ETV5 NCOA6

1.69e-0417262CID011979535
Diseaseamelogenesis imperfecta type 1E (implicated_via_orthology)

AMELX AMELY

7.47e-072262DOID:0110058 (implicated_via_orthology)
Diseaseautosomal dominant hypocalcemia (biomarker_via_orthology)

AMELX AMELY

4.47e-064262DOID:0090109 (biomarker_via_orthology)
Diseaseinterleukin 4 measurement

MAGI3 FNDC1

4.62e-0436262EFO_0008184
Diseasecolon cancer (is_implicated_in)

NCOA6 BRD4

4.62e-0436262DOID:219 (is_implicated_in)
DiseaseProstatic Neoplasms

ETV5 NCOA1 BRD4 PML

1.95e-03616264C0033578
DiseaseMalignant neoplasm of prostate

ETV5 NCOA1 BRD4 PML

1.95e-03616264C0376358
DiseaseGlioblastoma

BRD4 PML

2.21e-0379262C0017636
DiseaseGiant Cell Glioblastoma

BRD4 PML

2.49e-0384262C0334588
DiseaseGlioblastoma Multiforme

BRD4 PML

4.30e-03111262C1621958
Diseasecreatinine measurement, glomerular filtration rate

ETV5 NCOA6

4.76e-03117262EFO_0004518, EFO_0005208

Protein segments in the cluster

PeptideGeneStartEntry
PVVPAQQPVIPQQPM

AMELX

86

Q99217
QPQPPVHPMQPLPPQ

AMELX

141

Q99217
PHQPMQPQPPVQPMQ

AMELY

151

Q99218
MQQAPAPVPQQPPPP

BRD4

746

O60885
QTPLLPQPPMAQPPQ

BRD4

896

O60885
PPLQQSQVPPPEVRM

ANKRD17

2121

O75179
TPPIIPVLPQQFVPP

ESRP1

426

Q6NXG1
MVQPFTTIPFPPPPQ

RBFOX2

31

O43251
PMTAQPLPPQLQTPP

NPAT

896

Q14207
NEPIPQPMPFPPSII

MAGI3

681

Q5TCQ9
QLPAPVVPMTQPPAL

MAGEL2

71

Q9UJ55
PPGEVIQPLPIQMPK

COL11A2

1496

P13942
QMSEPIVPAAPPPPQ

ETV5

246

P41161
MQHVAPPPQPPQQQP

NCOA6

991

Q14686
PAMNIPQQQPPPPAA

CPEB2

66

Q7Z5Q1
MTPGRAPQQQPPPPV

FNDC1

996

Q4ZHG4
AMQPQQPSLPVPPPP

GARRE1

686

O15063
LPPQIPPQMPPQIPQ

COL8A1

36

P27658
QAMLPVALPPLPVPQ

MAMLD1

286

Q13495
IILMPQVQPGPPPCP

SMG8

921

Q8ND04
MPHPPPPPVMPQQVN

DROSHA

151

Q9NRR4
VPMPIPPPQSSLLQQ

NCOA1

1256

Q15788
PQQDPARPQEPTMPP

PML

11

P29590
PVMLPQPTSQPPVPQ

FGD1

241

P98174
QLVEPMVPLQLPPPL

ARHGAP5

1471

Q13017
VQGQLPPLMIPVFPP

SOX5

271

P35711
PQAPLQPLAQVPPQM

WNK2

781

Q9Y3S1
QPLAQVPPQMPPIPV

WNK2

786

Q9Y3S1
QPTRPPQPVLPPQPM

WNK2

971

Q9Y3S1
PPPLQAMQQPPPQKV

TOX4

466

O94842