Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionsteroid hydroxylase activity

CYP2A7 CYP19A1

1.11e-0334292GO:0008395
GeneOntologyMolecularFunctionaromatase activity

CYP2A7 CYP19A1

1.18e-0335292GO:0070330
GeneOntologyMolecularFunctionoxygen binding

CYP2A7 CYP19A1

1.31e-0337292GO:0019825
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

CYP2A7 CYP19A1

2.30e-0349292GO:0016712
DomainCyt_P450_E_grp-I

CYP2A7 CYP19A1

1.92e-0345272IPR002401
DomainCyt_P450_CS

CYP2A7 CYP19A1

2.65e-0353272IPR017972
DomainCYTOCHROME_P450

CYP2A7 CYP19A1

3.06e-0357272PS00086
Domain-

CYP2A7 CYP19A1

3.16e-03582721.10.630.10
Domainp450

CYP2A7 CYP19A1

3.16e-0358272PF00067
DomainCyt_P450

CYP2A7 CYP19A1

3.38e-0360272IPR001128
DomainRhoGAP

ARHGAP25 DEPDC1B

3.72e-0363272PF00620
DomainRHOGAP

ARHGAP25 DEPDC1B

3.84e-0364272PS50238
DomainRhoGAP_dom

ARHGAP25 DEPDC1B

3.84e-0364272IPR000198
Domain-

ARHGAP25 DEPDC1B

3.84e-03642721.10.555.10
DomainRho_GTPase_activation_prot

ARHGAP25 DEPDC1B

7.14e-0388272IPR008936
Pubmed

HNF1β drives glutathione (GSH) synthesis underlying intrinsic carboplatin resistance of ovarian clear cell carcinoma (OCCC).

HNF1B GCLC

2.16e-06330226520442
Pubmed

Defective folate metabolism causes germline epigenetic instability and distinguishes Hira as a phenotype inheritance biomarker.

TSHZ3 NSUN2

5.58e-051330234140513
Pubmed

Loss of Anks6 leads to YAP deficiency and liver abnormalities.

HNF1B WWTR1

1.09e-041830232886109
Pubmed

The p300/YY1/miR-500a-5p/HDAC2 signalling axis regulates cell proliferation in human colorectal cancer.

LRBA TRIM29 NSUN2 C2CD2L

1.21e-0429830430737378
Pubmed

Glomerulocystic kidney disease in mice with a targeted inactivation of Wwtr1.

HNF1B WWTR1

1.35e-042030217251353
Pubmed

Loss of Zeb2 in mesenchyme-derived nephrons causes primary glomerulocystic disease.

HNF1B WWTR1

1.50e-042130227591083
Pubmed

LATS-YAP/TAZ controls lineage specification by regulating TGFβ signaling and Hnf4α expression during liver development.

HNF1B WWTR1

2.88e-042930227358050
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

MACF1 PLEKHA6 LRBA DEPDC1B

4.52e-0442130436976175
Pubmed

Comparative expression profiling of 40 mouse cytochrome P450 genes in embryonic and adult tissues.

CYP2A7 CYP19A1

6.65e-044430212745259
Pubmed

Interrogating the protein interactomes of RAS isoforms identifies PIP5K1A as a KRAS-specific vulnerability.

FGFRL1 MACF1 DEPDC1B C2CD2L

6.67e-0446730430194290
Pubmed

Yap- and Cdc42-dependent nephrogenesis and morphogenesis during mouse kidney development.

HNF1B WWTR1

7.27e-044630223555292
Pubmed

An atlas of combinatorial transcriptional regulation in mouse and man.

HNF1B WWTR1 TRIM29 ASH2L ANKRD53

8.51e-0487730520211142
Pubmed

LATS1/2 suppress NFκB and aberrant EMT initiation to permit pancreatic progenitor differentiation.

HNF1B WWTR1

8.59e-045030231323030
Cytoband2p13.3

ARHGAP25 ANKRD53

2.56e-04363022p13.3
Cytoband11q23.3

TRIM29 C2CD2L

1.20e-037830211q23.3
CytobandEnsembl 112 genes in cytogenetic band chr2p13

ARHGAP25 ANKRD53

3.80e-03140302chr2p13
CytobandEnsembl 112 genes in cytogenetic band chr11q23

TRIM29 C2CD2L

9.10e-03220302chr11q23
GeneFamilyPHD finger proteins

JADE3 ASH2L

4.39e-039020288
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

ARHGAP25 PLEKHA6

2.15e-02206202682
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Hpcal4_(Substantia_Innominata_(SI))--|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

HNF1B CYP19A1 ANKRD53

2.92e-064329305de4f11e7315dce19efed14605d7e1704d61b3a
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Hpcal4_(Substantia_Innominata_(SI))-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

HNF1B CYP19A1 ANKRD53

2.92e-0643293ba1a8fd3119a26b65722898276045bf5ecf59768
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Hpcal4_(Substantia_Innominata_(SI))|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

HNF1B CYP19A1 ANKRD53

2.92e-0643293f1e6e1c386851e773f8aa44f112ebf7fdb887df1
ToppCellEpithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|World / Lineage, Cell type, age group and donor

WWTR1 MAP3K13 LRBA TMC5

6.33e-0618729481cc8435b2704a9a8287b3f54acaae0f11dd4ac7
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HNF1B MAP3K13 PLEKHA6 LRBA

7.17e-061932943866667dd221612589ae50f5c52f73a183a49ce6
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6b-L6b_Hsd17b2|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

POM121L2 TRIM29 CYP19A1

1.77e-0578293e5dbb0986cbee58fb1e5e464a3b003c4136246e7
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ARHGAP25 TMC5 GCLC

1.10e-0414429346177f0d6117e701bda86a99ac2a1b0e7ed66177
ToppCellTCGA-Head_and_Esophagus-Primary_Tumor-Esophageal_Carcinoma-Adenocarcinoma-3|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

HNF1B PLEKHA6 TMC5

1.15e-04146293e55b4acecf4e363b5afa287c747c2e58c4597f3a
ToppCellTCGA-Head_and_Esophagus-Primary_Tumor-Esophageal_Carcinoma-Adenocarcinoma|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

HNF1B PLEKHA6 TMC5

1.22e-0414929392a8931a51db619fb5f0638d319c02e7838f6559
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage_2|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

FGFRL1 TMC5 C2CD2L

1.51e-041602938aaf6ac4f33ea291387fdbf9ff1a91d559391774
ToppCellBasal_cells-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

KIAA1671 TSHZ3 TRIM29

1.59e-04163293679e25e5548d157d49a73057a3b5617dccda260f
ToppCellControl-Epithelial_cells-Airway_basal|Control / group, cell type (main and fine annotations)

TSHZ3 TRIM29 GCLC

1.83e-041712933965ced4be6db14265a90673502fceee425837ca
ToppCell343B-Myeloid-Macrophage-FABP4+_Macrophage_proliferating_2|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

COLEC11 HSPA12B DEPDC1B

1.86e-04172293e9b97f37bb1732ad9aa89c5e9b513d14022801ac
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L5-6_FEZF2_ANKRD20A1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KIAA1671 TSHZ3 ARHGAP25

1.93e-0417429399eb5e1aee136c7039e23b68a43a0fa3d775859f
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D122|Adult / Lineage, Cell type, age group and donor

CYP2A7 WWTR1 MAP3K13

2.00e-041762933fee8a367bb9755aca1b7fcc968b08e51b6e9436
ToppCellControl-Lymphoid-B|World / Disease state, Lineage and Cell class

ARHGAP25 PLEKHA6 JADE3

2.17e-041812939124f1a610cfc3355ad87921cd3eb5346956475d
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Adenocarcinoma_Mixed_Subtype|TCGA-Lung / Sample_Type by Project: Shred V9

HNF1B PLEKHA6 TMC5

2.17e-04181293c783c2ecca7ab8e07646fa92dc7d436d24939d03
ToppCellControl-Epithelial_cells-Airway_club|Control / group, cell type (main and fine annotations)

CYP2A7 WWTR1 TMC5

2.17e-04181293c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCellfacs-Liver-Hepatocytes-24m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FGFRL1 HNF1B GCLC

2.20e-04182293770ce9f3f4538d0181a0181543841bc964c68274
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-7|TCGA-Prostate / Sample_Type by Project: Shred V9

FGFRL1 NSUN2 C2CD2L

2.20e-04182293af16334fec2c757b03c84cf252d00e92fa81e4cd
ToppCellfacs-Liver-Hepatocytes-24m-Epithelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FGFRL1 HNF1B GCLC

2.20e-0418229377ab860e2add49dad0c1ffbfc64278ad499dfbd5
ToppCellfacs-Liver-Hepatocytes-24m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FGFRL1 HNF1B GCLC

2.20e-041822934921c7d5687cc79f896b39753bb621d7e3d2972f
ToppCellControl-Epithelial_cells-Airway_mucous|Control / group, cell type (main and fine annotations)

PLEKHA6 TMC5 CYP19A1

2.24e-0418329315d24a4fb1ffe6cbafbd54fcd7dde9ddcfbe03b2
ToppCellControl-Endothelial-Endothelial-Activated_Alv_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIAA1671 WWTR1 HSPA12B

2.24e-04183293e81c142770f44fd902b0631bc360c5b5339d4c75
ToppCellControl-Epithelial_cells-Airway_goblet|Control / group, cell type (main and fine annotations)

PLEKHA6 TMC5 CYP19A1

2.27e-04184293d92a71441e4e19f8c301999d8186f8e48e3cd162
ToppCellCOVID-19-Epithelial_cells-Airway_club|COVID-19 / group, cell type (main and fine annotations)

WWTR1 MAP3K13 TMC5

2.31e-04185293cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCellControl-Epithelial-Club|World / Disease state, Lineage and Cell class

CYP2A7 WWTR1 TMC5

2.35e-041862939798428691408e17ff2af2fe2d1b345f074d67e4
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HNF1B WWTR1 DEPDC1B

2.38e-04187293f124d2c699b717b7c02a1a70493f515b83dc2f4c
ToppCellRA-10._Endothelium_II|World / Chamber and Cluster_Paper

KIAA1671 COLEC11 WWTR1

2.46e-0418929375c248b9de5e2fb7a0baa8cdbab516e575cc4394
ToppCellRA-10._Endothelium_II|RA / Chamber and Cluster_Paper

KIAA1671 COLEC11 WWTR1

2.46e-04189293c81787a8c662db5d7814c583dd64562857629e81
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HNF1B WWTR1 DEPDC1B

2.46e-04189293e32172ad09e93f6ac6ea2b92145b2b73003f7970
ToppCellControl-Endothelial-Endothelial-Alv_Gen_Intermediate|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIAA1671 WWTR1 HSPA12B

2.46e-041892935d7ae1ead7f4fbaeec26f651833c9c2106e1e4d1
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Endothelial-endothelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIAA1671 WWTR1 HSPA12B

2.50e-04190293c8370c922e0cf0e0c36e02e1ed2b4053ad6a8073
ToppCellLPS_only-Endothelial-Endothelial-Alv_Cap|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIAA1671 WWTR1 HSPA12B

2.50e-04190293474cbbab8f3b0a6881fa6c92edb78e43999f9ab0
ToppCellAdult-Epithelial-club_cell|Adult / Lineage, Cell type, age group and donor

CYP2A7 WWTR1 TMC5

2.50e-04190293756bff697d30aec56c0ebfca94295f084a15bf37
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Endothelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIAA1671 WWTR1 HSPA12B

2.50e-041902935174f91a880f85bb20806023aa68bd4b8ca24ea5
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Endothelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIAA1671 WWTR1 HSPA12B

2.50e-0419029390e494cbfbed33a3a0d29bb7dae83f0c81580bcf
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

KIAA1671 MAP3K13 PLEKHA6

2.54e-041912933c464645d0e7e423f791bd63bf5bcf11f6b590d3
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

KIAA1671 MAP3K13 PLEKHA6

2.54e-041912931c1d13144259b998d4a0e85142f7afef2ef1e63f
ToppCellChildren_(3_yrs)-Epithelial|Children_(3_yrs) / Lineage, Cell type, age group and donor

WWTR1 MAP3K13 TMC5

2.54e-04191293e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCellChildren_(3_yrs)-Epithelial-club_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

CYP2A7 WWTR1 TMC5

2.54e-0419129323776c7302cead3881b39127398f3b3e0d27885e
ToppCellIPF-Epithelial-Club|World / Disease state, Lineage and Cell class

CYP2A7 WWTR1 TMC5

2.54e-041912933c88a6f1d74bb3b9173cd0ea3a63c6d9570e3954
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIAA1671 WWTR1 HSPA12B

2.58e-04192293c07d7b40b2aa4eb27ac85801c014a656e2fd01dc
ToppCellLPS-IL1RA+antiTNF-Endothelial|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIAA1671 WWTR1 HSPA12B

2.58e-0419229304f5a2e3dd6beff027b89d66eefdd92036e041af
ToppCellControl-Epithelial-Club|Control / Disease state, Lineage and Cell class

CYP2A7 WWTR1 TMC5

2.58e-04192293d84ed1ea4a03edaa18c804f75afb03bd7b1f0e16
ToppCellRV-10._Endothelium_II|RV / Chamber and Cluster_Paper

KIAA1671 COLEC11 WWTR1

2.62e-0419329301c2df9206f1527c578e808978e58196c35e72f5
ToppCellnucseq|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

COLEC11 PLEKHA6 LRBA

2.62e-04193293779276e775cb2492e8dd36436295a536084a6415
ToppCellLPS-antiTNF-Endothelial-Endothelial|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIAA1671 WWTR1 HSPA12B

2.62e-0419329302f633b016ab19bfa65bfd0cf32f000549a62148
ToppCellRV-10._Endothelium_II|World / Chamber and Cluster_Paper

KIAA1671 COLEC11 WWTR1

2.62e-041932932531266bc57339d4e2b22a88817008e32b8c1598
ToppCellEpithelial-club_cell|World / Lineage, Cell type, age group and donor

CYP2A7 WWTR1 TMC5

2.62e-041932932bdd09004fa433550958ec42ba4b06271a4aaf7c
ToppCellControl-Endothelial-Endothelial|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIAA1671 WWTR1 HSPA12B

2.62e-04193293aff0649c73c634bc6ff0dc7759b4693a9236bf05
ToppCellControl-Endothelial|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIAA1671 WWTR1 HSPA12B

2.62e-04193293c5f9fe03e64c211d4bcd4959e5b32f14841e336a
ToppCellLPS-antiTNF-Endothelial|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIAA1671 WWTR1 HSPA12B

2.62e-041932935122b1ffba42de190061be34ecdc6176f84e56a3
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HNF1B MAP3K13 LRBA

2.62e-0419329382e8a4c40299ffcdfd5a0da711bb9de6fb8a2eaa
ToppCellLPS-IL1RA-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIAA1671 MACF1 WWTR1

2.66e-041942930b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCellnucseq-Epithelial-Epithelial_Alveolar-Secretory/RAS-RAS|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CYP2A7 WWTR1 TMC5

2.66e-04194293a58841b34efe673671a9a059238e044a7254b279
ToppCellLPS-IL1RA-Endothelial-Endothelial|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIAA1671 WWTR1 HSPA12B

2.66e-041942931d39d968730a7e85b6161c1c8a6bd38afe9bcad7
ToppCellLPS-IL1RA-Endothelial|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIAA1671 WWTR1 HSPA12B

2.66e-0419429343f92b0533e26633dc94cce554045d641ef8fd76
ToppCellnucseq-Epithelial-Epithelial_Alveolar-Secretory/RAS|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CYP2A7 WWTR1 TMC5

2.66e-041942930cd4363627acd419e00d6d32f6dce10430aa6487
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HNF1B MAP3K13 LRBA

2.70e-041952936477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCellnormal_Lung-Epithelial_cells-Club|normal_Lung / Location, Cell class and cell subclass

CYP2A7 WWTR1 TMC5

2.70e-04195293b46544ad5af04f4dbc2643637caa3d2d50d922ae
ToppCellCOPD-Multiplet|COPD / Disease state, Lineage and Cell class

MACF1 WWTR1 TMC5

2.74e-041962936d02d494196e3f857d53eea46d9419690d43beca
ToppCellsevere_influenza-CD8+_Tem|World / disease group, cell group and cell class (v2)

KIAA1671 MACF1 ARHGAP25

2.74e-0419629340fb254abcab2e65affc5d6037e71893a031d264
ToppCellCOPD-Multiplet-Multiplet|COPD / Disease state, Lineage and Cell class

MACF1 WWTR1 TMC5

2.74e-04196293af4cdc61830685a888a1209826c23bcf54a43084
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_basal-Basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TSHZ3 TRIM29 GCLC

2.78e-041972931e915957ea6a4550ecb9d6ee4b232aa5800faf20
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

MACF1 PLEKHA6 REV3L

2.78e-04197293fdb92985f7df0c280b87d3e43c2394e70786a2c7
ToppCell10x3'2.3-week_17-19-Endothelial-stroma-tip_EC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

KIAA1671 WWTR1 HSPA12B

2.78e-04197293b212ff28ca2d1fea4140f186ab90941bdca21249
ToppCellnucseq-Endothelial|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

KIAA1671 WWTR1 HSPA12B

2.78e-04197293ebf9be068eaa658493fa7884fd19f34642922acb
ToppCellEpithelial_cells-Basal_cells|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

TSHZ3 TRIM29 GCLC

2.82e-041982934235005c49fc2b29ad3a0ee6b608f0109d04f775
ToppCell10x3'2.3-week_17-19-Endothelial-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

KIAA1671 WWTR1 HSPA12B

2.82e-041982931e83bec16dcd60460422625f89952ff506d6be51
ToppCell10x3'2.3-week_17-19-Endothelial|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

KIAA1671 WWTR1 HSPA12B

2.82e-041982932630a7a6e56febe5c0b0bde70dd7292fa1650c47
ToppCellwk_15-18-Endothelial|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

KIAA1671 WWTR1 HSPA12B

2.82e-04198293dcf453e22dba90c0ae349fa6c3d4c20758bb95af
ToppCellNS-critical-d_07-13|critical / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

WWTR1 TMC5 TRIM29

2.82e-04198293a6e11c87b31beffb6af190c64b4ef3ee1d9dab8d
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TMC5 TRIM29 GCLC

2.86e-041992938bf8d7cd774479f065bbbbcb5a4bd1aa91aa0d85
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TMC5 TRIM29 GCLC

2.86e-041992930c060ef64341659f4b1247d0264ac12e53a7e12e
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_basal-Suprabasal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TSHZ3 TRIM29 GCLC

2.86e-04199293f5c3561744e2a0e7716657cb521acb1d8f054b41
ToppCellfacs-Trachea-nan-3m-Mesenchymal|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FGFRL1 C11orf24 WWTR1

2.86e-0419929367f78c070c56e44fba36542041bf7fa1c291807c
ToppCellfacs-Trachea-nan-3m-Mesenchymal-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FGFRL1 C11orf24 WWTR1

2.86e-041992931ae244b563f85c1ee8d22698f478c842a4d9c7f5
ToppCellBronchial_Biopsy-Epithelial|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

TMC5 TRIM29 GCLC

2.86e-04199293ef5d8917c8d011184830a0b8197afc6266707b37
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Epithelial|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

MAP3K13 TMC5 TRIM29

2.90e-04200293f386a86b127433cbac306950443355bd723080ff
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

MAP3K13 TMC5 TRIM29

2.90e-04200293b75154417c215b8853186bff46d624ebd387ac4f
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated|COVID-19_Mild / Disease, condition lineage and cell class

KIAA1671 MACF1 ARHGAP25

2.90e-042002932281debd86e5d92e8fe0397aec9ef670800f7471
ToppCellNS-moderate-d_0-4-Epithelial|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MAP3K13 TMC5 TRIM29

2.90e-0420029364462a18afca3c1a8548a857924b8166058bf958
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TSHZ3 TRIM29 GCLC

2.90e-042002938827653738a931e4a4545e0c7d75be12bed40740
ToppCellTracheal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KIAA1671 MAP3K13 TMC5

2.90e-04200293d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCell5'-Airway_Nasal|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TMC5 TRIM29 GCLC

2.90e-04200293f6e967738b4f7b173d6e9977e305f77380dd6c8a
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-squamous_epithelial_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

MAP3K13 TMC5 TRIM29

2.90e-042002931c02a7f4047d1d2208cc522c6bb4a4989d7845bb
ToppCellILEUM-non-inflamed-(7)_CD36+_endothelial_cells|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

KIAA1671 WWTR1 HSPA12B

2.90e-0420029345755a597725015dc3ee36f9166f9e82f6f9c603
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-squamous_epithelial_cell-Epi-Squamous|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

MAP3K13 TMC5 TRIM29

2.90e-0420029303051d2190244208905e1611019d4b8fd200bae0
ToppCell5'-Airway_Nasal-Epithelial|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TMC5 TRIM29 GCLC

2.90e-04200293358d71329921451c7f5a56f1db0f9989af2299dc
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Gad2_(generic_SN/VTA_GABAergic_neuron)--|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

TMC5 CYP19A1

4.82e-0450292d902816790b9499793708fca2c7d2fa8025cfd2a
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Gad2_(generic_SN/VTA_GABAergic_neuron)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

TMC5 CYP19A1

4.82e-0450292318112bc843e6bcb6636fa8bdb05270f5fb4eda2
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Gad2_(generic_SN/VTA_GABAergic_neuron)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

TMC5 CYP19A1

4.82e-04502928903d7bd7c2fd2f4c06af7166ab210871a482b13
Diseasealkaline phosphatase measurement

GPR180 FGFRL1 MACF1 COLEC11 CYP2A7 ARHGAP25 LRBA CYP19A1

2.36e-061015278EFO_0004533
Diseaseendometrial endometrioid carcinoma

HNF1B CYP19A1

4.41e-0511272EFO_1001514
DiseaseMalignant neoplasm of breast

GPR180 MACF1 MAP3K13 LRBA TRIM29 CYP19A1

3.52e-041074276C0006142
Diseasebone density

FGFRL1 TSHZ3 ARHGAP25 CYP19A1

4.07e-04388274EFO_0003923
Diseasetotal blood protein measurement

MACF1 HNF1B HSPA12B CYP19A1

7.03e-04449274EFO_0004536
Diseaseperipheral arterial disease, traffic air pollution measurement

MACF1 TSHZ3 LRBA

7.29e-04194273EFO_0004265, EFO_0007908
Diseaseserum gamma-glutamyl transferase measurement

COLEC11 HNF1B LRBA HSPA12B GCLC

1.29e-03914275EFO_0004532
Diseaseinformation processing speed, response to cranial radiation therapy

ARHGAP25 HSPA12B

1.29e-0358272EFO_0004363, EFO_0010950
DiseaseDrugs used in diabetes use measurement

MACF1 HNF1B TSHZ3

1.60e-03255273EFO_0009924
Diseaseserum albumin measurement

MACF1 CYP2A7 HNF1B CYP19A1

1.95e-03592274EFO_0004535
Diseaseresponse to selective serotonin reuptake inhibitor

CYP2A7 TSHZ3

2.56e-0382272EFO_0005658
DiseaseAutism Spectrum Disorders

TSHZ3 NSUN2

2.75e-0385272C1510586
Diseasecholelithiasis

HNF1B LRBA

2.94e-0388272EFO_0004799
DiseaseHbA1c measurement

MACF1 HNF1B ARHGAP25 C2CD2L

3.13e-03675274EFO_0004541

Protein segments in the cluster

PeptideGeneStartEntry
MWALKKPFQPFQRTR

DEPDC1B

511

Q8WUY9
RQRPGKMTWPNNIVK

ASH2L

211

Q9UBL3
SSMPWNKRQPKLQGK

NSUN2

431

Q08J23
RKPTVKRPTMWNVSN

ANKRD53

376

Q8N9V6
RPQSNWKESANKMSP

KIAA1671

1141

Q9BY89
SQQWARPRFTQPSKM

FGFRL1

141

Q8N441
IQSTNWQTMRFKPPP

GCLC

401

P48506
DNVNRRSWKSFMPPN

MACF1

126

O94854
SPRQLFKASNMTQRW

LRBA

2201

P50851
MKKSQSRPLQWDSTP

GPR180

271

Q86V85
TVPAIWKQPAKQFMR

HSPA12B

206

Q96MM6
MKQTWQSKPRNRPSF

MAP3K13

386

O43283
NPMQQKWTKPARAGS

C2CD2L

316

O14523
NNPELWKTTRPFFMK

CYP19A1

136

P11511
MSVWQQRKSRGKLPP

CYP2A7

21

P20853
PMRTFNKWRSGEPNN

COLEC11

221

Q9BWP8
PTKNMSPKEQFWGRQ

JADE3

736

Q92613
TWRNRKPPERKMSQN

NXF2

101

Q9GZY0
PTNKKMRRNRFKWGP

HNF1B

226

P35680
SLMRSQSPKAQPQTW

TRIM29

546

Q14134
WRRFPMKKSQNSPLG

POM121L2

76

Q96KW2
ASNDPRNFVPNKMWK

C11orf24

21

Q96F05
SMKRNPNAPVTKAGW

PLEKHA6

51

Q9Y2H5
LWKTAFSAMTQNPRP

REV3L

1951

O60673
DWKMQSRKRTQTLPN

ARHGAP25

431

P42331
VFLANKQWMPPRSNR

RHPN2P1

401

A8MT19
TDNNNPKRWSKPRKR

TSHZ3

246

Q63HK5
LWSQKPVQMARPSAR

FP248

136

Q71RG6
FNKRAETQMPWSSPR

ZNF786

221

Q8N393
LMMNFQPPSKAWRAS

TMC5

816

Q6UXY8
QPPSKAWRASQMMTF

TMC5

821

Q6UXY8
LFNSVMNPKPSSWRK

WWTR1

31

Q9GZV5