Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainDUF1908

MAST4 MAST1 MAST2 MAST3

1.03e-104614PF08926
DomainMA_Ser/Thr_Kinase_dom

MAST4 MAST1 MAST2 MAST3

1.03e-104614IPR015022
DomainMAST_pre-PK_dom

MAST4 MAST1 MAST2 MAST3

1.03e-104614IPR023142
Domain-

MAST4 MAST1 MAST2 MAST3

1.03e-1046141.20.1480.20
DomainAGC-kinase_C

MAST4 GRK5 MAST1 MAST2 MAST3

1.06e-0656615IPR000961
DomainAGC_KINASE_CTER

MAST4 GRK5 MAST1 MAST2 MAST3

1.06e-0656615PS51285
DomainS_TK_X

MAST4 GRK5 MAST1 MAST2 MAST3

1.06e-0656615SM00133
DomainPkinase_C

MAST1 MAST2 MAST3

3.48e-0442613PF00433
DomainFerric_reduct

STEAP4 DUOX2

6.78e-0412612PF01794
DomainFe3_Rdtase_TM_dom

STEAP4 DUOX2

6.78e-0412612IPR013130
DomainPDZ

MAST4 MAST1 MAST2 MAST3

1.16e-03141614PF00595
DomainPDZ

MAST4 MAST1 MAST2 MAST3

1.39e-03148614SM00228
Domain-

MAST4 MAST1 MAST2 MAST3

1.46e-031506142.30.42.10
DomainPDZ

MAST4 MAST1 MAST2 MAST3

1.50e-03151614PS50106
DomainPDZ

MAST4 MAST1 MAST2 MAST3

1.54e-03152614IPR001478
DomainCation_ATPase_N

ATP13A2 ATP2A3

1.55e-0318612SM00831
DomainATPase_P-typ_cation-transptr_N

ATP13A2 ATP2A3

1.73e-0319612IPR004014
DomainHAD-like_dom

LPIN3 ATP13A2 ATP2A3

2.20e-0379613IPR023214
DomainC_TYPE_LECTIN_1

SFTPA2 CHODL SFTPA1

2.28e-0380613PS00615
DomainLectin_C

SFTPA2 CHODL SFTPA1

2.62e-0384613PF00059
DomainCLECT

SFTPA2 CHODL SFTPA1

2.62e-0384613SM00034
DomainC_TYPE_LECTIN_2

SFTPA2 CHODL SFTPA1

2.71e-0385613PS50041
DomainNUDIX

NUDT6 MUTYH

2.77e-0324612PF00293
DomainC-type_lectin-like

SFTPA2 CHODL SFTPA1

2.80e-0386613IPR001304
DomainNUDIX

NUDT6 MUTYH

3.24e-0326612PS51462
Domain-

NUDT6 MUTYH

3.76e-03286123.90.79.10
DomainNUDIX_hydrolase_dom-like

NUDT6 MUTYH

3.76e-0328612IPR015797
Domain-

SFTPA2 CHODL SFTPA1

3.93e-03976133.10.100.10
DomainNUDIX_hydrolase_dom

NUDT6 MUTYH

4.02e-0329612IPR000086
DomainC-type_lectin-like/link

SFTPA2 CHODL SFTPA1

4.16e-0399613IPR016186
Domain-

ATP13A2 ATP2A3

4.89e-03326123.40.1110.10
Domain-

ATP13A2 ATP2A3

4.89e-03326122.70.150.10
DomainCTDL_fold

SFTPA2 CHODL SFTPA1

5.17e-03107613IPR016187
DomainATPase_P-typ_cyto_domN

ATP13A2 ATP2A3

5.83e-0335612IPR023299
Domain-

CHI3L1 IDUA

5.83e-03356123.20.20.80
DomainSer/Thr_kinase_AS

MAST4 GRK5 MAST1 MAST2 MAST3

6.15e-03357615IPR008271
DomainP_typ_ATPase

ATP13A2 ATP2A3

6.15e-0336612IPR001757
DomainATPase_P-typ_P_site

ATP13A2 ATP2A3

6.15e-0336612IPR018303
DomainATPASE_E1_E2

ATP13A2 ATP2A3

6.15e-0336612PS00154
DomainS_TKc

MAST4 GRK5 MAST1 MAST2 MAST3

6.29e-03359615SM00220
DomainATPase_P-typ_transduc_dom_A

ATP13A2 ATP2A3

6.49e-0337612IPR008250
DomainE1-E2_ATPase

ATP13A2 ATP2A3

6.49e-0337612PF00122
DomainPROTEIN_KINASE_ST

MAST4 GRK5 MAST1 MAST2 MAST3

6.51e-03362615PS00108
Pubmed

Binding of PTEN to specific PDZ domains contributes to PTEN protein stability and phosphorylation by microtubule-associated serine/threonine kinases.

MAST1 MAST2 MAST3

2.16e-08462315951562
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

LPIN3 RPAP1 KMT5C GRK5 IPP HERC2 IDUA MAST2 IL17RD ATP13A2 ATP2A3 ARSG

4.98e-071105621235748872
Pubmed

Major Effect of Oxidative Stress on the Male, but Not Female, SP-A1 Type II Cell miRNome.

SFTPA2 SFTPA1

3.13e-06262231354704
Pubmed

Signaling Pathways That Mediate Alveolar Macrophage Activation by Surfactant Protein A and IL-4.

SFTPA2 SFTPA1

3.13e-06262235444643
Pubmed

Surfactant-associated protein A inhibits LPS-induced cytokine and nitric oxide production in vivo.

SFTPA2 SFTPA1

3.13e-06262210749762
Pubmed

The flagellum of Pseudomonas aeruginosa is required for resistance to clearance by surfactant protein A.

SFTPA2 SFTPA1

3.13e-06262217593964
Pubmed

Studies of the structure of lung surfactant protein SP-A.

SFTPA2 SFTPA1

3.13e-0626222610270
Pubmed

Surfactant protein-A binds group B streptococcus enhancing phagocytosis and clearance from lungs of surfactant protein-A-deficient mice.

SFTPA2 SFTPA1

3.13e-0626229922219
Pubmed

Maternal surfactant protein A influences the immunoprotective properties of milk in a murine model.

SFTPA2 SFTPA1

3.13e-06262224858142
Pubmed

Surfactant protein-A--deficient mice display an exaggerated early inflammatory response to a beta-resistant strain of influenza A virus.

SFTPA2 SFTPA1

3.13e-06262211867335
Pubmed

Pneumocystis murina colonization in immunocompetent surfactant protein A deficient mice following environmental exposure.

SFTPA2 SFTPA1

3.13e-06262219228388
Pubmed

SP-A preserves airway homeostasis during Mycoplasma pneumoniae infection in mice.

SFTPA2 SFTPA1

3.13e-06262219494306
Pubmed

An 11-nt sequence polymorphism at the 3'UTR of human SFTPA1 and SFTPA2 gene variants differentially affect gene expression levels and miRNA regulation in cell culture.

SFTPA2 SFTPA1

3.13e-06262224793167
Pubmed

Sex differences in the acute in vivo effects of different human SP-A variants on the mouse alveolar macrophage proteome.

SFTPA2 SFTPA1

3.13e-06262224954098
Pubmed

Characterization of a second human pulmonary surfactant-associated protein SP-A gene.

SFTPA2 SFTPA1

3.13e-0626221372511
Pubmed

Lung effector memory and activated CD4+ T cells display enhanced proliferation in surfactant protein A-deficient mice during allergen-mediated inflammation.

SFTPA2 SFTPA1

3.13e-06262221257967
Pubmed

The Pseudomonas aeruginosa flagellum confers resistance to pulmonary surfactant protein-A by impacting the production of exoproteases through quorum-sensing.

SFTPA2 SFTPA1

3.13e-06262221205009
Pubmed

Surfactant protein A modulates neuroinflammation in adult mice upon pulmonary infection.

SFTPA2 SFTPA1

3.13e-06262238964703
Pubmed

Differential Regulation of Human Surfactant Protein A Genes, SFTPA1 and SFTPA2, and Their Corresponding Variants.

SFTPA2 SFTPA1

3.13e-06262234917085
Pubmed

Surfactant protein A integrates activation signal strength to differentially modulate T cell proliferation.

SFTPA2 SFTPA1

3.13e-06262222219327
Pubmed

Surfactant protein A is a principal and oxidation-sensitive microbial permeabilizing factor in the alveolar lining fluid.

SFTPA2 SFTPA1

3.13e-06262215890661
Pubmed

Enhanced lung injury and delayed clearance of Pneumocystis carinii in surfactant protein A-deficient mice: attenuation of cytokine responses and reactive oxygen-nitrogen species.

SFTPA2 SFTPA1

3.13e-06262215385504
Pubmed

A TLR4-interacting SPA4 peptide inhibits LPS-induced lung inflammation.

SFTPA2 SFTPA1

3.13e-06262223475791
Pubmed

Surfactant protein A associated with respiratory distress syndrome in Korean preterm infants: evidence of ethnic difference.

SFTPA2 SFTPA1

3.13e-06262223038062
Pubmed

Surfactant protein A binds flagellin enhancing phagocytosis and IL-1β production.

SFTPA2 SFTPA1

3.13e-06262224312669
Pubmed

Correlation analysis between single nucleotide polymorphisms of pulmonary surfactant protein A gene and pulmonary tuberculosis in the Han population in China.

SFTPA2 SFTPA1

3.13e-06262224984162
Pubmed

Effect of cysteine 85 on biochemical properties and biological function of human surfactant protein A variants.

SFTPA2 SFTPA1

3.13e-06262217580966
Pubmed

Isolation and characterization of cDNA clones for the 35-kDa pulmonary surfactant-associated protein.

SFTPA2 SFTPA1

3.13e-0626223755136
Pubmed

Differential effects of innate immune variants of surfactant protein-A1 (SFTPA1) and SP-A2 (SFTPA2) in airway function after Klebsiella pneumoniae infection and sex differences.

SFTPA2 SFTPA1

3.13e-06262229394894
Pubmed

Surfactant protein-A suppresses eosinophil-mediated killing of Mycoplasma pneumoniae in allergic lungs.

SFTPA2 SFTPA1

3.13e-06262222384248
Pubmed

Surfactant protein A enhances production of secretory leukoprotease inhibitor and protects it from cleavage by matrix metalloproteinases.

SFTPA2 SFTPA1

3.13e-06262219155504
Pubmed

Surfactant Protein A can Affect the Surface Tension of the Eustachian Tube and Macrophage Migration.

SFTPA2 SFTPA1

3.13e-06262236102297
Pubmed

Role of surfactant protein-A (SP-A) in lung injury in response to acute ozone exposure of SP-A deficient mice.

SFTPA2 SFTPA1

3.13e-06262217307210
Pubmed

Surfactant protein A modulates induction of regulatory T cells via TGF-β.

SFTPA2 SFTPA1

3.13e-06262222474025
Pubmed

The collagen-like region of surfactant protein A (SP-A) is required for correction of surfactant structural and functional defects in the SP-A null mouse.

SFTPA2 SFTPA1

3.13e-06262211504713
Pubmed

Surfactant protein A promotes western diet-induced hepatic steatosis and fibrosis in mice.

SFTPA2 SFTPA1

3.13e-06262238553537
Pubmed

Surfactant protein A reduces TLR4 and inflammatory cytokine mRNA levels in neonatal mouse ileum.

SFTPA2 SFTPA1

3.13e-06262233510368
Pubmed

Genetic complexity of the human innate host defense molecules, surfactant protein A1 (SP-A1) and SP-A2--impact on function.

SFTPA2 SFTPA1

3.13e-06262219392648
Pubmed

Polymorphisms in the surfactant protein a gene are associated with the susceptibility to recurrent urinary tract infection in chinese women.

SFTPA2 SFTPA1

3.13e-06262220448439
Pubmed

Humanized SFTPA1 and SFTPA2 transgenic mice reveal functional divergence of SP-A1 and SP-A2: formation of tubular myelin in vivo requires both gene products.

SFTPA2 SFTPA1

3.13e-06262220048345
Pubmed

Functional assessment and phenotypic heterogeneity of SFTPA1 and SFTPA2 mutations in interstitial lung diseases and lung cancer.

SFTPA2 SFTPA1

3.13e-06262232855221
Pubmed

Surfactant protein A suppresses lipopolysaccharide-induced IL-10 production by murine macrophages.

SFTPA2 SFTPA1

3.13e-06262211342662
Pubmed

Surfactant protein A-deficient mice are susceptible to group B streptococcal infection.

SFTPA2 SFTPA1

3.13e-0626229126996
Pubmed

Type IV pilus of Pseudomonas aeruginosa confers resistance to antimicrobial activities of the pulmonary surfactant protein-A.

SFTPA2 SFTPA1

3.13e-06262224080545
Pubmed

Lung development in the mouse embryo.

SFTPA2 SFTPA1

3.13e-0626222050021
Pubmed

Murine pulmonary surfactant SP-A gene: cloning, sequence, and transcriptional activity.

SFTPA2 SFTPA1

3.13e-0626221443158
Pubmed

Surfactant Protein A and B Gene Polymorphisms and Risk of Respiratory Distress Syndrome in Late-Preterm Neonates.

SFTPA2 SFTPA1

3.13e-06262227835691
Pubmed

Genetic Variation in Surfactant Protein-A2 Delays Resolution of Eosinophilia in Asthma.

SFTPA2 SFTPA1

3.13e-06262231350355
Pubmed

Genetic complexity of the human surfactant-associated proteins SP-A1 and SP-A2.

SFTPA2 SFTPA1

3.13e-06262223069847
Pubmed

Ablation of SP-A has a negative impact on the susceptibility of mice to Klebsiella pneumoniae infection after ozone exposure: sex differences.

SFTPA2 SFTPA1

3.13e-06262219055785
Pubmed

Human Surfactant Protein SP-A1 and SP-A2 Variants Differentially Affect the Alveolar Microenvironment, Surfactant Structure, Regulation and Function of the Alveolar Macrophage, and Animal and Human Survival Under Various Conditions.

SFTPA2 SFTPA1

3.13e-06262234484180
Pubmed

Surfactant protein A limits Pneumocystis murina infection in immunosuppressed C3H/HeN mice and modulates host response during infection.

SFTPA2 SFTPA1

3.13e-06262215857803
Pubmed

Surfactant protein-A reduces translocation of mediators from the lung into the circulation.

SFTPA2 SFTPA1

3.13e-06262220715984
Pubmed

Effects of surfactant protein-A on the interaction of Pneumocystis murina with its host at different stages of the infection in mice.

SFTPA2 SFTPA1

3.13e-06262219335775
Pubmed

Altered surfactant protein A gene expression and protein metabolism associated with repeat exposure to inhaled endotoxin.

SFTPA2 SFTPA1

3.13e-06262212922979
Pubmed

Cryptococcus neoformans is resistant to surfactant protein A mediated host defense mechanisms.

SFTPA2 SFTPA1

3.13e-06262218159253
Pubmed

Differences in the alveolar macrophage toponome in humanized SP-A1 and SP-A2 transgenic mice.

SFTPA2 SFTPA1

3.13e-06262233141765
Pubmed

Regulatory roles of SP-A and exosomes in pneumonia-induced acute lung and kidney injuries.

SFTPA2 SFTPA1

3.13e-06262237256132
Pubmed

Surfactant protein a attenuates generalized and localized neuroinflammation in neonatal mice.

SFTPA2 SFTPA1

3.13e-06262236871846
Pubmed

Innate immunity of surfactant protein A in experimental otitis media.

SFTPA2 SFTPA1

3.13e-06262231378117
Pubmed

Surfactant Protein A, a Novel Regulator for Smooth Muscle Phenotypic Modulation and Vascular Remodeling-Brief Report.

SFTPA2 SFTPA1

3.13e-06262233267655
Pubmed

Immunosuppressed surfactant protein A-deficient mice have increased susceptibility to Pneumocystis carinii infection.

SFTPA2 SFTPA1

3.13e-06262211237812
Pubmed

Human SP-A protein variants derived from one or both genes stimulate TNF-alpha production in the THP-1 cell line.

SFTPA2 SFTPA1

3.13e-06262210781424
Pubmed

SP-A is necessary for increased clearance of alveolar DPPC with hyperventilation or secretagogues.

SFTPA2 SFTPA1

3.13e-06262212676766
Pubmed

Surfactant protein A deficiency exacerbates renal interstitial fibrosis following obstructive injury in mice.

SFTPA2 SFTPA1

3.13e-06262227916681
Pubmed

Surfactant protein A inhibits alveolar macrophage cytokine production by CD14-independent pathway.

SFTPA2 SFTPA1

3.13e-06262212959932
Pubmed

Surfactant protein secreted by the maturing mouse fetal lung acts as a hormone that signals the initiation of parturition.

SFTPA2 SFTPA1

3.13e-06262215044702
Pubmed

Structural comparison of recombinant pulmonary surfactant protein SP-A derived from two human coding sequences: implications for the chain composition of natural human SP-A.

SFTPA2 SFTPA1

3.13e-0626221986781
Pubmed

Surfactant protein A is a required mediator of keratinocyte growth factor after experimental marrow transplantation.

SFTPA2 SFTPA1

3.13e-06262212740217
Pubmed

Surfactant protein-A plays an important role in lung surfactant clearance: evidence using the surfactant protein-A gene-targeted mouse.

SFTPA2 SFTPA1

3.13e-06262218083768
Pubmed

Structural characterisation of human proteinosis surfactant protein A.

SFTPA2 SFTPA1

3.13e-06262211087951
Pubmed

Surfactant protein-A inhibits Aspergillus fumigatus-induced allergic T-cell responses.

SFTPA2 SFTPA1

3.13e-06262216120217
Pubmed

SP-A2 contributes to miRNA-mediated sex differences in response to oxidative stress: pro-inflammatory, anti-apoptotic, and anti-oxidant pathways are involved.

SFTPA2 SFTPA1

3.13e-06262229202868
Pubmed

The alveolar macrophage toponome of female SP-A knockout mice differs from that of males before and after SP-A1 rescue.

SFTPA2 SFTPA1

3.13e-06262235322074
Pubmed

Surfactant protein A regulates surfactant phospholipid clearance after LPS-induced injury in vivo.

SFTPA2 SFTPA1

3.13e-06262212060563
Pubmed

Surfactant Protein-A Protects against IL-13-Induced Inflammation in Asthma.

SFTPA2 SFTPA1

3.13e-06262232245819
Pubmed

Characteristics of surfactant from SP-A-deficient mice.

SFTPA2 SFTPA1

3.13e-0626229700084
Pubmed

Novel role for surfactant protein A in gastrointestinal graft-versus-host disease.

SFTPA2 SFTPA1

3.13e-06262222508928
Pubmed

Relationship between surfactant protein A polymorphisms and allergic rhinitis in a Chinese Han population.

SFTPA2 SFTPA1

3.13e-06262220963503
Pubmed

Human SP-A1 (SFTPA1) variant-specific 3' UTRs and poly(A) tail differentially affect the in vitro translation of a reporter gene.

SFTPA2 SFTPA1

3.13e-06262220693318
Pubmed

Absence of SP-A modulates innate and adaptive defense responses to pulmonary influenza infection.

SFTPA2 SFTPA1

3.13e-06262211839553
Pubmed

Type IV pilus glycosylation mediates resistance of Pseudomonas aeruginosa to opsonic activities of the pulmonary surfactant protein A.

SFTPA2 SFTPA1

3.13e-06262225605768
Pubmed

Surfactant protein A decreases lung injury and mortality after murine marrow transplantation.

SFTPA2 SFTPA1

3.13e-06262212204891
Pubmed

Role of surfactant protein-A in nitric oxide production and mycoplasma killing in congenic C57BL/6 mice.

SFTPA2 SFTPA1

3.13e-06262212959946
Pubmed

Surfactant protein-A enhances ureaplasmacidal activity in vitro.

SFTPA2 SFTPA1

3.13e-06262220197455
Pubmed

Mutations in MAST1 Cause Mega-Corpus-Callosum Syndrome with Cerebellar Hypoplasia and Cortical Malformations.

MAST1 MAST2 MAST3

5.12e-061962330449657
Pubmed

cAMP response element binding protein is required for differentiation of respiratory epithelium during murine development.

SFTPA2 SFTPA1 CHI3L1

8.11e-062262321408140
Pubmed

The role of pulmonary collectin N-terminal domains in surfactant structure, function, and homeostasis in vivo.

SFTPA2 SFTPA1

9.37e-06362212015304
Pubmed

Surfactant proteins SP-A and SP-D: structure, function and receptors.

SFTPA2 SFTPA1

9.37e-06362216213021
Pubmed

Interaction of surfactant protein A with peroxiredoxin 6 regulates phospholipase A2 activity.

SFTPA2 SFTPA1

9.37e-06362216330552
Pubmed

Macrophage-independent fungicidal action of the pulmonary collectins.

SFTPA2 SFTPA1

9.37e-06362212857753
Pubmed

Surfactant protein-A inhibits mycoplasma-induced dendritic cell maturation through regulation of HMGB-1 cytokine activity.

SFTPA2 SFTPA1

9.37e-06362220810986
Pubmed

Altered surfactant function and structure in SP-A gene targeted mice.

SFTPA2 SFTPA1

9.37e-0636228790375
Pubmed

Disruption of the SP-A/SP-R210L (MYO18Aα) pathway prolongs gestation and reduces fetal survival during lipopolysaccharide-induced parturition in late gestation.

SFTPA2 SFTPA1

9.37e-06362238349123
Pubmed

Functionally recurrent rearrangements of the MAST kinase and Notch gene families in breast cancer.

MAST1 MAST2

9.37e-06362222101766
Pubmed

Surfactant dysfunction in SP-A-/- and iNOS-/- mice with mycoplasma infection.

SFTPA2 SFTPA1

9.37e-06362216917077
Pubmed

Surfactant protein A (SP-A) gene targeted mice.

SFTPA2 SFTPA1

9.37e-0636229813377
Pubmed

The concentration of surfactant protein-A in amniotic fluid decreases in spontaneous human parturition at term.

SFTPA2 SFTPA1

9.37e-06362218828058
Pubmed

Coccidioides posadasii infection alters the expression of pulmonary surfactant proteins (SP)-A and SP-D.

SFTPA2 SFTPA1

9.37e-06362215588319
Pubmed

Sequential targeted deficiency of SP-A and -D leads to progressive alveolar lipoproteinosis and emphysema.

SFTPA2 SFTPA1

9.37e-06362212376353
InteractionMAST4 interactions

MAST4 MAST1 MAST2 MAST3

1.08e-0626614int:MAST4
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

SFTPA2 CHODL SFTPA1

1.85e-04414931298
GeneFamilyCollectins

SFTPA2 SFTPA1

3.19e-0410492491
GeneFamilyPDZ domain containing

MAST4 MAST1 MAST2 MAST3

7.58e-041524941220
CoexpressionMULLIGHAN_MLL_SIGNATURE_1_DN

METAP1 ISYNA1 MAST4 PTPRCAP CHI3L1 ATP2A3

2.12e-05238626M18841
CoexpressionHE_LIM_SUN_FETAL_LUNG_C2_PDC_CELL

PTPRCAP SLC15A4 PPM1J ATP13A2 ATP2A3

2.59e-05147625M45743
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-DC-DC3-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PHEX PTPRCAP SLC15A4 SLC25A53 ATP2A3 MAST3

3.47e-071996267271dbeca9aa838b88ad44d00059263a29c0316b
ToppCell356C-Myeloid-Dendritic-pDC|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

PHEX SLC15A4 PPM1J ATP13A2 ARSG

3.21e-06163625ae9c5eb19657ea94b7f2357cbc8679acd697b8fe
ToppCellILEUM-inflamed-(3)_pDC|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

PHEX SLC15A4 SFTPA1 PPM1J ATP13A2

4.67e-06176625b9f847dd55703e413f3cd815eef5724fffaf13b3
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-Myeloid-pDC|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PHEX SFTPA2 SLC15A4 PPM1J ATP13A2

5.08e-06179625bbd4f8e988ef3f343aaedbc992b70f2bb6aff5f6
ToppCellControl-Epithelial_cells-AT2|Control / group, cell type (main and fine annotations)

MAST4 SFTPA2 PTPRG STEAP4 SFTPA1

5.22e-06180625198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCellCOPD-Epithelial-ATII|World / Disease state, Lineage and Cell class

MAST4 SFTPA2 PTPRG STEAP4 SFTPA1

5.65e-061836258e9aab4eeec2e282c2cab9bfca6dbf40d660c7b9
ToppCellIPF-Epithelial-ATII|IPF / Disease state, Lineage and Cell class

MAST4 SFTPA2 PTPRG STEAP4 SFTPA1

5.96e-06185625563b4e6d92bb5d77a3829556116a8e99aebac615
ToppCellIPF-Epithelial-ATII|World / Disease state, Lineage and Cell class

MAST4 SFTPA2 PTPRG STEAP4 SFTPA1

6.12e-061866256a4ff2da0af0f5e590d9f9daa5b5e9ac8c868947
ToppCell(0)_Myeloid-(01)_Dendritic_cell-(011)_pDC|(01)_Dendritic_cell / immune cells in Peripheral Blood (logTPM normalization)

PHEX SLC15A4 PPM1J ATP13A2 ATP2A3

6.28e-06187625068502efa3f0ac4cea2fa4a18d1c2f686a4fba54
ToppCellCOPD-Epithelial-ATII|COPD / Disease state, Lineage and Cell class

MAST4 SFTPA2 PTPRG STEAP4 SFTPA1

6.44e-06188625eb6d79d733b53f64ca615bb777c64ed456866549
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D231|Adult / Lineage, Cell type, age group and donor

MAST4 SFTPA2 PTPRG STEAP4 SFTPA1

6.61e-06189625dab54a52358f66a8a9460cd6089a06c5fa7e7a5d
ToppCellControl-Multiplet-Multiplet|World / Disease state, Lineage and Cell class

MAST4 SFTPA2 PTPRG STEAP4 SFTPA1

7.14e-061926251bfd022d5b87cf8a5d5069f559339a553a52a0a2
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MAST4 SFTPA2 PTPRG STEAP4 SFTPA1

7.32e-06193625fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

PHEX PTPRG GRK5 ADAMTS15 HIF3A

7.32e-0619362599525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

PHEX PTPRG GRK5 ADAMTS15 HIF3A

7.32e-06193625b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MAST4 SFTPA2 PTPRG STEAP4 SFTPA1

7.32e-06193625f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

PHEX PTPRG GRK5 ADAMTS15 HIF3A

7.50e-06194625e93de9428c986b8943fc169258847c650cfab0e5
ToppCelltumor_Lung|World / Location, Cell class and cell subclass

MAST4 SFTPA2 STEAP4 SFTPA1 CHI3L1

7.50e-061946257e6b8a30f8d08252ad3f1df826d6f7c0ba997c2c
ToppCellControl-Epithelial-ATII|Epithelial / Disease state, Lineage and Cell class

MAST4 SFTPA2 PTPRG STEAP4 SFTPA1

7.50e-06194625a01de094f7bfd099bcbb2f94224690a2efb887b4
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-DC-pDC-Z|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PHEX SLC15A4 PPM1J ATP13A2 ATP2A3

7.69e-0619562506051de72b5c1e0d483a28b14dabd247dfca0ed9
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-DC-pDC|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PHEX SLC15A4 PPM1J ATP13A2 ATP2A3

7.69e-061956253aa44633c72658545aa2b35bf9d532c62f36a451
ToppCellAT2_cells-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

SFTPA2 PTPRG STEAP4 SFTPA1 CHI3L1

7.69e-06195625bb45a17871a8a2593bc16a95f22e3c239c49985b
ToppCell356C-Epithelial_cells-Epithelial-B_(AT2)-|356C / Donor, Lineage, Cell class and subclass (all cells)

SFTPA2 PTPRG STEAP4 SFTPA1 CHI3L1

8.08e-0619762506ed8f293d4ee89f14dc2f43d6cae93bbc02508a
ToppCell356C-Epithelial_cells-Epithelial-B_(AT2)|356C / Donor, Lineage, Cell class and subclass (all cells)

SFTPA2 PTPRG STEAP4 SFTPA1 CHI3L1

8.08e-06197625c115d0a45545ed24259ad88872231bf4d4d389d2
ToppCell(54)_pDC|World / shred on Cell_type and subtype

PHEX SLC15A4 SFTPA1 PPM1J ATP13A2

9.35e-06203625b8ba3e51770ff7b45cd02472f3e63aa4d5816f6f
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Mgp_(Mgp)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

PHEX LPIN3 SEC16B SFTPA1

1.36e-0510462411d91471b6c4fa6b00a91d9fd4db72ee60d1f801
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

PHEX LPIN3 SEC16B SFTPA1

1.36e-05104624424a58b04c8b5108b70f15d8353c8e4b9db1e730
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Mgp_(Mgp)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

PHEX LPIN3 SEC16B SFTPA1

1.36e-051046249b05ae514437eb0c8b1b23607ae8cbc371ffa85b
ToppCellLPS_only-Myeloid-Dendritic_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAP1 SLC15A4 SIGLEC1 ATP13A2

5.41e-05148624cb9365663f9cba35d47b5dd9079f42e88b70d915
ToppCellCOVID_non-vent-Lymphocytic-Dendritic-pDC|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

PHEX SLC15A4 PPM1J ATP13A2

7.32e-0516062461f4cb4eb4313d8318aadbb99595a6cb7fd919f7
ToppCellCOVID_non-vent-Lymphocytic-Dendritic|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

PHEX SLC15A4 PPM1J ATP13A2

7.32e-0516062434b4f710cfcb6ec370b8b074f3cbfe272f392cec
ToppCellLAM-Lymphoid-pDC|LAM / Condition, Lineage and Cell class

PHEX PTPRCAP SLC15A4 PPM1J

7.50e-05161624bb5b44713e4da4406cdaa79dcf2aa9f97e3cf75a
ToppCellFetal_29-31_weeks-Epithelial-club_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ADRA1B MAST4 HIF3A AWAT2

7.68e-051626245c9bc3c3857a99d8a3caf359a7eb279ce9cc1c81
ToppCellPND01-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_prolif|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PTPRCAP IPP PPM1J MUTYH

8.24e-0516562466f0364098d82629aa2ec1dfe0c5ad23de7c2c12
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PHEX PTPRCAP SLC15A4 PPM1J

9.25e-0517062492e765ae0d3adb38d3b22fddb873fd5ccad3fd44
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PHEX PTPRCAP SLC15A4 PPM1J

9.25e-051706249f8b215caa1afa3cd7104c06fca7cfd790640f66
ToppCellCOVID_vent-Lymphocytic-Dendritic-pDC|COVID_vent / Disease condition, Lineage, Cell class and subclass

PHEX SLC15A4 PPM1J ATP13A2

9.46e-05171624779c951d274ecbd1d546ac425d6c8e718623be5a
ToppCellCOVID_vent-Lymphocytic-Dendritic|COVID_vent / Disease condition, Lineage, Cell class and subclass

PHEX SLC15A4 PPM1J ATP13A2

9.46e-05171624debbb071d260639b16269c94d172766908325c58
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-Myeloid-pDC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PHEX SFTPA2 SLC15A4 PPM1J

9.68e-051726243aed10e6db48254f4cae12fbe52d1a1fc6cf2dce
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-pDC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PHEX SLC15A4 PPM1J MAST3

9.68e-05172624b84610f1e5889a655652800c2b3270d264bfe1a9
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_dendritic-plasmacytoid_dendritic_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PHEX SLC15A4 PPM1J ATP13A2

1.03e-0417562497fe431f224b592b3076632d101e19136c138dcc
ToppCelldroplet-Marrow-BM-30m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRCAP SLC15A4 SLC25A53 ATP13A2

1.06e-04176624d4075796c38b775fe721abb47426e662a0d415e3
ToppCell390C-Epithelial_cells-Epithelial-B_(AT2)|390C / Donor, Lineage, Cell class and subclass (all cells)

SFTPA2 STEAP4 SFTPA1 CHI3L1

1.13e-04179624466da2bc3bfc534ffe111c8c28ece7a3cfa08051
ToppCell390C-Epithelial_cells-Epithelial-B_(AT2)-|390C / Donor, Lineage, Cell class and subclass (all cells)

SFTPA2 STEAP4 SFTPA1 CHI3L1

1.13e-04179624f4bdebb77d39e63160fbf3a85a340ce4d52b7cfd
ToppCell5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ISLR2 ISYNA1 ABCA4 HIF3A

1.13e-0417962440c65e8623547aeb80f9cd2366e29072467ce069
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-NP-L5_NP_VISp_Trhr_Cpne7|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CRYBB3 F5 AWAT2

1.17e-0468623cdb805182f7169fbc3bec31adec3a4e088281757
ToppCell3'_v3-Lung-Myeloid_Dendritic-pDC|Lung / Manually curated celltypes from each tissue

PHEX SLC15A4 PPM1J ATP13A2

1.18e-041816243d7f089fb434fbc989f1fa159e22133ae00b2487
ToppCelltumor_Lung-Myeloid_cells-pDCs|tumor_Lung / Location, Cell class and cell subclass

PHEX SLC15A4 PPM1J ATP13A2

1.18e-04181624c864ffeb9234b8c29754afc91c85a972889617f4
ToppCellsystemic_lupus_erythematosus-treated-Myeloid-plasmacytoid_dendritic_cell-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

PHEX SLC15A4 PPM1J ATP13A2

1.20e-041826249bbe8062aa562dc3b9c299581faf6ebbcb72a9f7
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-Myeloid-pDC|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PHEX SFTPA2 SLC15A4 PPM1J

1.20e-0418262402c0824373a0ecebc922d4ca848ace9d570722c4
ToppCellsystemic_lupus_erythematosus-treated-Myeloid-plasmacytoid_dendritic_cell|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

PHEX SLC15A4 PPM1J ATP13A2

1.20e-041826244602a98df7045e2c70b7560abfba9b444fbd5d30
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SYNJ2 GRK5 CHI3L1 F5

1.23e-041836243c516fe5083f02bad1f464ed284010b4131a833c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SYNJ2 GRK5 CHI3L1 F5

1.23e-04183624eb559ae3ae252d9365c24ef557dd49b78ed6d898
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SYNJ2 GRK5 CHI3L1 F5

1.23e-041836249c2689d76fc6d30f5ab093428aa669d0a98953cf
ToppCellnormal_Lung-B_lymphocytes-GrB-secreting_B_cells|normal_Lung / Location, Cell class and cell subclass

PHEX SLC15A4 PPM1J ATP13A2

1.23e-04183624c930b957d16f9b0904b6c424acd914532e5cc137
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Dendritic-plasmacytoid_dendritic_cell-DC_c4-LILRA4|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PHEX SLC15A4 PPM1J ATP13A2

1.23e-041836243b123571e10c132227aff65648b4b3c6acb4bd00
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Dendritic-plasmacytoid_dendritic_cell|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PHEX SLC15A4 PPM1J ATP13A2

1.23e-04183624df6fd0927b6e4cf9a1583969a68096e4bccfbace
ToppCell(7)_DC_plasmacytoid|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

SLC15A4 SFTPA1 PPM1J ATP13A2

1.23e-041836242c6475c935b5a90931be6b3c53f1f707cfcd11f4
ToppCellmyeloid-Dendritic_cell-Plasmacytoid_dendritic_cell|World / Lineage, cell class and subclass

PHEX SLC15A4 PPM1J ATP13A2

1.25e-0418462411619778bc773ecd1a9867330be04deaf324f31e
ToppCellCOVID-19-Epithelial_cells-AT2|COVID-19 / group, cell type (main and fine annotations)

MAST4 SFTPA2 STEAP4 SFTPA1

1.25e-04184624369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCell10x5'-bone_marrow-Myeloid_Dendritic-pDC|bone_marrow / Manually curated celltypes from each tissue

PHEX SLC15A4 PPM1J ATP13A2

1.25e-041846242817d530863e85dfdcd143b7a3dc5fc58a9cd98b
ToppCellLeuk-UTI-Other-RBC|Leuk-UTI / Disease, Lineage and Cell Type

PHEX SLC15A4 PPM1J ATP13A2

1.28e-041856245b5dd856d6efc0539d92533cff134bbc3f98be45
ToppCellAT2_cells-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

SFTPA2 STEAP4 SFTPA1 CHI3L1

1.28e-041856243b3268e3f99121124e33086cac88479808d31630
ToppCellCOVID-19-Epithelial_cells-Airway_club|COVID-19 / group, cell type (main and fine annotations)

MAST4 SFTPA2 STEAP4 SFTPA1

1.28e-04185624cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SYNJ2 GRK5 CHI3L1 F5

1.28e-041856249197f074e769d54031ec41abfc65fcc0c6552c7e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SYNJ2 GRK5 CHI3L1 F5

1.28e-04185624ce7d62394b09c26ca65b8cdb280afec5e25bbb62
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SYNJ2 GRK5 CHI3L1 F5

1.28e-04185624b848b63aff4d9dbb9e66a85876d4c7c6dacd0579
ToppCellLeuk-UTI-Other|Leuk-UTI / Disease, Lineage and Cell Type

PHEX SLC15A4 PPM1J ATP13A2

1.28e-04185624895e8087e97ac0eab3446385e6e0dd24bea7f42c
ToppCellILEUM-inflamed-(3)_MNP-(3)_pDC|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

PHEX SLC15A4 SFTPA1 ATP13A2

1.28e-04185624308a98f111895071d8772bc010554471cc12fab2
ToppCellPBMC-Severe-Myeloid-pDC-pDC-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PHEX SLC15A4 PPM1J ATP13A2

1.31e-0418662431df1eafa3010bc1be6fc4d4689f1393d69b6b13
ToppCellPBMC-Severe-Myeloid-pDC|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PHEX SLC15A4 PPM1J ATP13A2

1.31e-04186624eaa431ccd4cdd36fe06a44987603ec9979025aa8
ToppCellPBMC-Severe-Myeloid-pDC|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

PHEX SLC15A4 PPM1J ATP13A2

1.31e-04186624b95be984e308d4f9061274a35995ec558d434e74
ToppCellPBMC-Severe-Myeloid-pDC-pDC-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PHEX SLC15A4 PPM1J ATP13A2

1.31e-041866248f7949740286f64e034d1eb533ebc2c6f71ae966
ToppCellPBMC-Severe-Myeloid-pDC-pDC|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

PHEX SLC15A4 PPM1J ATP13A2

1.31e-0418662495c7318e521fb6aa02e244b1e81e6b2a62107756
ToppCellhealthy_donor-Lymphocytic-Dendritic|healthy_donor / Disease condition, Lineage, Cell class and subclass

PHEX SLC15A4 PPM1J ATP13A2

1.31e-04186624916f2aeea4989ba7a29e071e348a51010f010223
ToppCellmyeloid-Dendritic_cell-Plasmacytoid_dendritic_cell|Dendritic_cell / Lineage, cell class and subclass

PHEX SLC15A4 PPM1J ATP13A2

1.31e-04186624858134580a09ed8a5eb6d6413d8ca9265904dfc1
ToppCellPBMC-Severe-Myeloid-pDC-pDC|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PHEX SLC15A4 PPM1J ATP13A2

1.31e-04186624b70cd94c651b56dcf2e55554533a5f1130845390
ToppCellCOVID-19_Severe-Myeloid-pDC|COVID-19_Severe / Disease group, lineage and cell class

PHEX SLC15A4 PPM1J ATP13A2

1.31e-041866243db5ed69d49e5d79f990aca0295ddce4c297a05c
ToppCellhealthy_donor-Lymphocytic-Dendritic-pDC|healthy_donor / Disease condition, Lineage, Cell class and subclass

PHEX SLC15A4 PPM1J ATP13A2

1.31e-0418662445f66619e45d590c7365a51782d4ac46b7d31fde
ToppCellControl-Epithelial-ATII|World / Disease state, Lineage and Cell class

MAST4 SFTPA2 STEAP4 SFTPA1

1.31e-04186624f4b6e401e19a71beddc73d8a1e08359f7c4025cf
ToppCellSMG-Goblet|World / shred by cell class for bronchial biopsy

SFTPA2 TM9SF3 STEAP4 ATP2A3

1.34e-041876245178118bdec91495253c88f58fd908cf831de7ef
ToppCellCOPD-Epithelial-ATII|Epithelial / Disease state, Lineage and Cell class

MAST4 SFTPA2 PTPRG SFTPA1

1.34e-04187624030af361f8bdcd0aff4ec1922702833325cf74d8
ToppCellLAM-Lymphoid-pDC|Lymphoid / Condition, Lineage and Cell class

PHEX SLC15A4 PPM1J ATP13A2

1.34e-041876244d9ffd2bbdf1c9869e28991ce9331e4ccf3c0166
ToppCellLeuk-UTI-Myeloid-pDC|Leuk-UTI / Disease, Lineage and Cell Type

PHEX SFTPA1 PPM1J ATP13A2

1.34e-04187624e3035b1f65ab12b8f01799b8e5d6633b9b584a06
ToppCellcontrol-pDC|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PHEX SLC15A4 PPM1J ATP13A2

1.34e-04187624c78aee98b32719aa45811b620fc97be1ecf5fd53
ToppCellIPF-Epithelial-ATII|Epithelial / Disease state, Lineage and Cell class

SFTPA2 PTPRG SFTPA1 CHI3L1

1.36e-041886245f5fad2773e421760e67dbace23fd1f847a2e1e0
ToppCellCOVID-19-lung-Artery_EC|lung / Disease (COVID-19 only), tissue and cell type

MAST4 PTPRG SYNJ2 HIF3A

1.36e-04188624eecd7482b3c97d7f49993cb17edfab30c61232fc
ToppCellCOVID-19_Severe-pDC|World / disease group, cell group and cell class

PHEX SLC15A4 PPM1J ATP13A2

1.36e-041886244c8e328b8206120708b05ea3c5865a0200dc5c4e
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D175|Adult / Lineage, Cell type, age group and donor

MAST4 PTPRG STEAP4 SFTPA1

1.36e-04188624ec38def1fdbb34ed9b30244806975bd5a4370164
ToppCellmyeloid-pDC|myeloid / Lineage and Cell class

PHEX SLC15A4 PPM1J ATP13A2

1.36e-04188624a2dc4bbeca2bdc00c51825dd65a699c54c72f241
ToppCell3'_v3-lymph-node_spleen-Myeloid_Dendritic-pDC|lymph-node_spleen / Manually curated celltypes from each tissue

PHEX SLC15A4 PPM1J ATP13A2

1.39e-041896246c2ace61a7d62bcf7e76b73e2da8b722d03e713b
ToppCellCOVID-19_Mild-Myeloid-pDC|COVID-19_Mild / Disease group, lineage and cell class

PHEX SLC15A4 PPM1J ATP13A2

1.39e-04189624c6cfd6aa21c19f2c62d80218bbc924e14e82aada
ToppCellIPF-Epithelial-Club|IPF / Disease state, Lineage and Cell class

MAST4 SFTPA2 STEAP4 SFTPA1

1.39e-04189624f3fcef008ef252b29ac6d567fef27f9acf9cd70f
ToppCellControl-Myeloid-pDC|Control / Disease group, lineage and cell class

PHEX SLC15A4 PPM1J ATP13A2

1.39e-0418962446770b99da42f11f10cfc67cea8562342d60b867
ToppCellPBMC-Control-Myeloid-pDC|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

PHEX SLC15A4 PPM1J ATP13A2

1.42e-04190624adffa93635da10251f28b2089fd96b189775c8b4
ToppCellControl-Epithelial-ATII|Control / Disease state, Lineage and Cell class

MAST4 SFTPA2 STEAP4 SFTPA1

1.42e-04190624d50902a3abcc18aafa36d83cc2c6e07d7f7cb197
ToppCellPBMC-Control-Myeloid-pDC-pDC|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PHEX SLC15A4 PPM1J ATP13A2

1.42e-041906249a91bf1ea105029e6412d0d9060bca325299ce26
ToppCellPBMC-Control-Myeloid-pDC-pDC|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

PHEX SLC15A4 PPM1J ATP13A2

1.42e-0419062439c8ddc2639bf3e986dae11fbae61a735614b604
ToppCellCOPD-Myeloid-Mast|Myeloid / Disease state, Lineage and Cell class

MAST4 SYNJ2 DUOX2 ATP2A3

1.42e-04190624379dbac19110b76079a7a53209569e060a852acb
ToppCellPBMC-Control-Myeloid-pDC|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PHEX SLC15A4 PPM1J ATP13A2

1.42e-041906242c1c079fd411c03bc3f383aa927eea9446716960
Diseaselevel of leukocyte immunoglobulin-like receptor subfamily B member 4 in blood serum

SFTPA2 SFTPA1

3.78e-055582OBA_2042200
Diseaselevel of prosaposin in blood serum

SFTPA2 SFTPA1

3.78e-055582OBA_2044552
Diseasenewborn respiratory distress syndrome (biomarker_via_orthology)

SFTPA2 SFTPA1

5.67e-056582DOID:12716 (biomarker_via_orthology)
DiseaseIron deficiency anemia

DUOX2 F5

5.67e-056582HP_0001891
DiseaseNeuronal Ceroid-Lipofuscinoses

ATP13A2 ARSG

5.67e-056582C0027877
Diseasenewborn respiratory distress syndrome (is_implicated_in)

SFTPA2 SFTPA1

7.92e-057582DOID:12716 (is_implicated_in)
Diseaseleukocyte immunoglobulin-like receptor subfamily B member 4 measurement

SFTPA2 SFTPA1

1.06e-048582EFO_0801768
Diseasecomplement C1q tumor necrosis factor-related protein 1 measurement

SFTPA2 SFTPA1

2.47e-0412582EFO_0801493
Diseasegranulins measurement

SFTPA2 SFTPA1

2.47e-0412582EFO_0008141
DiseaseHamman-Rich syndrome

SFTPA2 SFTPA1

3.40e-0414582C0085786
Diseasebacterial pneumonia (biomarker_via_orthology)

SFTPA2 SFTPA1

3.40e-0414582DOID:874 (biomarker_via_orthology)
DiseasePolyposis, Adenomatous Intestinal

F5 MUTYH

4.48e-0416582C2713442
DiseaseFamilial Intestinal Polyposis

F5 MUTYH

4.48e-0416582C2713443
Diseasetotal iron binding capacity

IPP DUOX2 F5

4.94e-0478583EFO_0006334
DiseaseAdenomatous Polyposis Coli

F5 MUTYH

5.07e-0417582C0032580
Diseaseerythritol measurement

IPP MAST2

5.07e-0417582EFO_0021171
Diseasecoagulation factor V measurement

MAST4 F5

7.05e-0420582EFO_0008087
DiseaseFamilial Idiopathic Pulmonary Fibrosis

SFTPA2 SFTPA1

7.05e-0420582C4721952
Diseasevenous thromboembolism, plasminogen activator inhibitor 1 measurement

GRK5 F5

7.78e-0421582EFO_0004286, EFO_0004792
DiseaseIdiopathic Pulmonary Fibrosis

SFTPA2 SFTPA1

7.78e-0421582C1800706
DiseaseS-6-hydroxywarfarin measurement

ABCA4 SFTPA2 PTPRG CYP27B1 SFTPA1

7.82e-04368585EFO_0803326
Diseaseotitis media (implicated_via_orthology)

PHEX IDUA

8.55e-0422582DOID:10754 (implicated_via_orthology)
Diseasevenous thromboembolism, tissue plasminogen activator measurement

GRK5 F5

9.36e-0423582EFO_0004286, EFO_0004791
Diseasecongenital diaphragmatic hernia (biomarker_via_orthology)

SFTPA2 SFTPA1

1.02e-0324582DOID:3827 (biomarker_via_orthology)
DiseaseD dimer measurement

ABCA4 F5

1.59e-0330582EFO_0004507
Diseasefactor XI measurement, venous thromboembolism

GRK5 F5

1.59e-0330582EFO_0004286, EFO_0004694
Diseaseunipolar depression, bipolar disorder, seasonality measurement

SFTPA2 SFTPA1

1.59e-0330582EFO_0003761, EFO_0006876, MONDO_0004985
Diseasepulmonary sarcoidosis (is_marker_for)

SFTPA1 CHI3L1

1.81e-0332582DOID:13406 (is_marker_for)
Diseasepulmonary fibrosis (is_marker_for)

SFTPA1 CHI3L1

1.81e-0332582DOID:3770 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
RRKASGDPYWAYSGA

PTPRG

51

P23470
YPEGGGSRVLSFNWY

ABCA4

326

P78363
LGGCAYTYRPWTRGG

ADRA1B

381

P35368
YTYRPWTRGGSLERS

ADRA1B

386

P35368
AAPRGRSLYGAGLWE

ARSG

261

Q96EG1
PYSAGYREGFLWKRG

ADAP1

126

O75689
DPAHGGSWLRGAVYY

ATP2A3

281

Q93084
LDPDINGRRYYWRGP

ADAMTS15

31

Q8TE58
NGRRYYWRGPEDSGD

ADAMTS15

36

Q8TE58
NAYWFRGLRPGTNYS

ISLR2

551

Q6UXK2
YAVGGYTRLQGGRWS

IPP

291

Q9Y573
SWPTRSGRKEANYYG

ISYNA1

86

Q9NPH2
RYAYVRGGGDPWTNG

MCOLN1

146

Q9GZU1
RWAPELGASLGYREY

CYP27B1

16

O15528
LYFPQSDSGLGARRW

LPIN3

396

Q9BQK8
WRGVGPASRNSGLYN

IL17RD

41

Q8NFM7
GDINTDPWAGYRYTG

METAP1

71

P53582
GGWTARYFQSRGPRQ

KMT5C

71

Q86Y97
ELYTWGRGNYGRLGH

HERC2

571

O95714
RDYWPGPGKFSRTDY

DUOX2

411

Q9NRD8
GFDGLDLAWLYPGRR

CHI3L1

131

P36222
RTYGPGPSAGYRWAS

NUDT6

16

P53370
GWPAFYQGAYRGATR

FAM83D

116

Q9H4H8
QSPSRGLEWLGRTYY

IGHV6-1

61

A0A0B4J1U7
YRPRWGALGDYLSFT

PSENEN

81

Q9NZ42
GRRWSLASLPSSGYG

MAST1

86

Q9Y2H9
RLSGYCGSPWRVIGY

ATP13A2

36

Q9NQ11
YGRGFTKNSWGLLPY

AWAT2

261

Q6E213
GTWVGYEFPGYRGRQ

CRYBB3

156

P26998
YGLERAKWPYRGGGG

HOXD11

66

P31277
GSYRVRALDYWARPG

IDUA

616

P35475
YVPYVLTGRWTFGRG

HRH3

91

Q9Y5N1
GRRWSLASLPSSGYG

MAST2

226

Q6P0Q8
GRRWSLASLPSSGYG

MAST3

81

O60307
GRRWSLASLPSSGYG

MAST4

281

O15021
YWPGGQALSRYLLDN

ETFBKMT

96

Q8IXQ9
RYGLSPDYWGLGCLI

GRK5

361

P34947
RRLGLGSYPDWGSNY

FLAD1

306

Q8NFF5
YLGSPFGGWLADARL

SLC15A4

86

Q8N697
YDWNGGTPLLYAVRG

RFXANK

186

O14593
YLWSGARASYGVRRG

HNRNPUL1

241

Q9BUJ2
LGYYADPSGWGARSP

TBR1

536

Q16650
TWSPGALQYYGRAEL

SYNJ2

836

O15056
YWEPRLARLNNGGSY

F5

1931

P12259
SGGYYHPARLGAALW

PTPRCAP

61

Q14761
TGQYRFLARSGGYLW

HIF3A

301

Q9Y2N7
REPSRGQGLCFYYWG

PPM1J

141

Q5JR12
WAGLGYYSRGRRLQE

MUTYH

171

Q9UIF7
SLGYYRGFWPVLARN

SLC25A53

171

Q5H9E4
VNYTNWYRGEPAGRG

SFTPA2

206

Q8IWL1
SQPYSPAGSRWRDYG

PEX14

96

O75381
VNYTNWYRGEPAGRG

SFTPA1

206

Q8IWL2
GLGGPYLYQWNDDRC

CHODL

156

Q9H9P2
SRYLGFGRDAWVYPD

CNGA4

191

Q8IV77
RPDDGRGYAGYFDLW

RBMXL3

126

Q8N7X1
LERAFGYYGPLRSVW

SRSF3

26

P84103
LGWLGADRFYLGYPA

TM2D1

131

Q9BX74
WGTEYPRSLSYGAIG

PHEX

561

P78562
YGGKRFLSPSNLRWY

STEAP4

401

Q687X5
GVPEGTSYRWYRDGQ

SIGLEC1

921

Q9BZZ2
RLWAVAASYGQGGYL

RPAP1

676

Q9BWH6
QGYSEAPGYRSALWL

SEC16B

746

Q96JE7
YFGGSLYARQGGRRW

TM9SF3

341

Q9HD45
WDNLYSRYGGGPAVN

USP33

791

Q8TEY7