Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionmicrotubule motor activity

KIF4A KIF4B

1.24e-0370152GO:0003777
GeneOntologyMolecularFunctioniron-sulfur cluster binding

KIF4A KIF4B

1.53e-0378152GO:0051536
GeneOntologyMolecularFunctionmetal cluster binding

KIF4A KIF4B

1.73e-0383152GO:0051540
GeneOntologyBiologicalProcessmitotic spindle midzone assembly

KIF4A KIF4B

2.70e-0511152GO:0051256
GeneOntologyBiologicalProcessmitotic spindle elongation

KIF4A KIF4B

3.24e-0512152GO:0000022
GeneOntologyBiologicalProcessmitotic cytokinesis

KIF4A KIF4B RAB11FIP3

4.14e-0595153GO:0000281
GeneOntologyBiologicalProcessspindle midzone assembly

KIF4A KIF4B

4.47e-0514152GO:0051255
GeneOntologyBiologicalProcessspindle elongation

KIF4A KIF4B

4.47e-0514152GO:0051231
GeneOntologyBiologicalProcesscytoskeleton-dependent cytokinesis

KIF4A KIF4B RAB11FIP3

9.83e-05127153GO:0061640
GeneOntologyBiologicalProcesscytokinesis

KIF4A KIF4B RAB11FIP3

3.97e-04204153GO:0000910
MousePhenoincreased dendritic spine number

KIF4A KIF4B

3.22e-063152MP:0021019
MousePhenobehavioral developmental delay

KIF4A KIF4B

3.00e-058152MP:0021165
MousePhenoabnormal dendritic spine number

KIF4A KIF4B

4.81e-0510152MP:0021017
MousePhenoimpaired long-term object recognition memory

KIF4A KIF4B

4.00e-0428152MP:0014367
DomainKinesin_motor_CS

KIF4A KIF4B

4.21e-0441142IPR019821
DomainKinesin-like_fam

KIF4A KIF4B

4.63e-0443142IPR027640
DomainKINESIN_MOTOR_1

KIF4A KIF4B

4.85e-0444142PS00411
DomainKinesin

KIF4A KIF4B

4.85e-0444142PF00225
Domain-

KIF4A KIF4B

4.85e-04441423.40.850.10
DomainKinesin_motor_dom

KIF4A KIF4B

4.85e-0444142IPR001752
DomainKISc

KIF4A KIF4B

4.85e-0444142SM00129
DomainKINESIN_MOTOR_2

KIF4A KIF4B

4.85e-0444142PS50067
Pubmed

Missense Pathogenic variants in KIF4A Affect Dental Morphogenesis Resulting in X-linked Taurodontism, Microdontia and Dens-Invaginatus.

KIF4A KIF4B

1.74e-07215231616463
Pubmed

Structural basis for the ATP-induced isomerization of kinesin.

KIF4A KIF4B

1.74e-07215223500491
Pubmed

KIF4 regulates neuronal morphology and seizure susceptibility via the PARP1 signaling pathway.

KIF4A KIF4B

1.74e-07215236482480
Pubmed

Chromokinesin Kif4 promotes proper anaphase in mouse oocyte meiosis.

KIF4A KIF4B

1.74e-07215231067151
Pubmed

Assignment of the kinesin family member 4 genes (KIF4A and KIF4B) to human chromosome bands Xq13.1 and 5q33.1 by in situ hybridization.

KIF4A KIF4B

1.74e-07215210773663
Pubmed

A novel microtubule-based motor protein (KIF4) for organelle transports, whose expression is regulated developmentally.

KIF4A KIF4B

1.74e-0721527929562
Pubmed

Kif4 regulates the expression of VEGFR1 through the PI3K/Akt signaling pathway in RAW264.7 monocytes/macrophages.

KIF4A KIF4B

1.74e-07215228350061
Pubmed

Binding of murine leukemia virus Gag polyproteins to KIF4, a microtubule-based motor protein.

KIF4A KIF4B

1.74e-0721529658142
Pubmed

Cellular motor protein KIF-4 associates with retroviral Gag.

KIF4A KIF4B

1.74e-07215210559369
Pubmed

KIF4 regulates midzone length during cytokinesis.

KIF4A KIF4B

1.74e-07215221565503
Pubmed

Whole genome expression microarray reveals novel roles for Kif4 in monocyte/macrophage cells.

KIF4A KIF4B

1.74e-07215231486502
Pubmed

Kif4 interacts with EB1 and stabilizes microtubules downstream of Rho-mDia in migrating fibroblasts.

KIF4A KIF4B

1.74e-07215224658398
Pubmed

The multiple functions of kinesin-4 family motor protein KIF4 and its clinical potential.

KIF4A KIF4B

1.74e-07215230081192
Pubmed

Identification of the human homologue of mouse KIF4, a kinesin superfamily motor protein.

KIF4A KIF4B

5.21e-07315210978527
Pubmed

KIF4 mediates anterograde translocation and positioning of ribosomal constituents to axons.

KIF4A KIF4B

5.21e-07315219158085
Pubmed

CircKIF4A enhances osteosarcoma proliferation and metastasis by sponging MiR-515-5p and upregulating SLC7A11.

KIF4A KIF4B

5.21e-07315235579738
Pubmed

Tumor formation via loss of a molecular motor protein.

KIF4A KIF4B

5.21e-07315216890532
Pubmed

KIF4 motor regulates activity-dependent neuronal survival by suppressing PARP-1 enzymatic activity.

KIF4A KIF4B

5.21e-07315216630823
Pubmed

Kinesin KIF4 regulates intracellular trafficking and stability of the human immunodeficiency virus type 1 Gag polyprotein.

KIF4A KIF4B

1.04e-06415218684836
Pubmed

Kif4 Is Essential for Mouse Oocyte Meiosis.

KIF4A KIF4B

1.04e-06415228125646
Pubmed

Genetic mapping in the mouse of Kif4, a gene encoding a kinesin-like motor protein.

KIF4A KIF4B

3.64e-0671529196009
Pubmed

Unusual chromatin status and organization of the inactive X chromosome in murine trophoblast giant cells.

KIF4A KIF4B

3.64e-06715223362347
Pubmed

Kinesin family in murine central nervous system.

KIF4A KIF4B

3.64e-0671521447303
Pubmed

Contribution of epigenetic landscapes and transcription factors to X-chromosome reactivation in the inner cell mass.

KIF4A KIF4B

7.80e-061015229101321
Pubmed

Characterization of nuclear factors modulating the apolipoprotein D promoter during growth arrest: implication of PARP-1, APEX-1 and ERK1/2 catalytic activities.

KIF4A KIF4B

9.53e-061115220493910
Pubmed

Functional analysis of human microtubule-based motor proteins, the kinesins and dyneins, in mitosis/cytokinesis using RNA interference.

KIF4A KIF4B

9.53e-061115215843429
Pubmed

Large-scale concatenation cDNA sequencing.

KCNV1 HECTD2 SCAMP1 RAB11FIP3

8.33e-055681549110174
Pubmed

A "double adaptor" method for improved shotgun library construction.

KCNV1 HECTD2 SCAMP1 RAB11FIP3

8.67e-055741548619474
Pubmed

All kinesin superfamily protein, KIF, genes in mouse and human.

KIF4A KIF4B

1.15e-043715211416179
Pubmed

Genetic variations strongly influence phenotypic outcome in the mouse retina.

KIF4A KIF4B

1.78e-044615221779340
Pubmed

Phenotypic annotation of the mouse X chromosome.

KIF4A KIF4B

3.13e-046115220548051
InteractionKIF4B interactions

KIF4A KIF4B

4.68e-0514152int:KIF4B
CytobandEnsembl 112 genes in cytogenetic band chr8q23

KCNV1 EIF3E

1.26e-0451152chr8q23
CytobandEnsembl 112 genes in cytogenetic band chr16p12

SBK1 ARHGAP17

1.42e-03172152chr16p12
GeneFamilyKinesins|Pleckstrin homology domain containing

KIF4A KIF4B

4.11e-0446122622
CoexpressionAtlasalpha beta T cells, T.8SP24int.Th, 4- 8+ TCRhi 24int, Thymus, avg-3

SBK1 KIF4A HECTD2 DUSP10

7.58e-05339154GSM399382_500
CoexpressionAtlasB cells, B.T2.Sp, IgD+ IgM+ CD45R+ CD24+ CD19+ AA4.1+ CD23+, Spleen, avg-3

SBK1 ARHGAP17 GNS DUSP10

8.39e-05348154GSM538216_500
CoexpressionAtlasB cells, B.T1.Sp, IgD+ IgM+ CD45R+ CD24+ CD19+ AA4.1+ CD23-, Spleen, avg-3

SBK1 ARHGAP17 GNS DUSP10

8.87e-05353154GSM538213_500
CoexpressionAtlasB cells, B.FrE.FL, AA4.1+ IgM+ CD19+ CD43- CD24+, Fetal Liver, avg-3

SBK1 KIF4A ARHGAP17 DUSP10

1.09e-04372154GSM538204_500
CoexpressionAtlasB cells, B.FrE.BM, CD19+ IgM+ AA4.1+ HSA+, Bone marrow, avg-3

SBK1 ARHGAP17 GNS DUSP10

1.13e-04376154GSM399438_500
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-double_negative_T_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PERM1 SCAMP1 RAB11FIP3

2.25e-05168153de1042267407719f19eb3f580a5df0c9cd0e8273
ToppCelldroplet-Marrow-nan-24m-Hematologic-erythroid_progenitor|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SBK1 GNS DUSP10

2.42e-05172153910ec7794ea4000db4ef1e2c34e08dbc0243df2c
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-Zbtb32+_B|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SBK1 GNS DUSP10

2.50e-0517415328ec25767bbd4fd898738f9f4d2b585dc91b5adf
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MPL SBK1 KCNV1

2.59e-05176153212e643c50c68462d4b016428ab30eeb7868ef40
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-Zbtb32+_B_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SBK1 GNS DUSP10

2.86e-05182153632014a6e042d09302f4631ca3a1da36af7a7c98
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-Zbtb32+_B_cell-Zbtb32+_B_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SBK1 GNS DUSP10

2.86e-051821538737142aa4c8301fb5b0ad5bef596471ac316743
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SBK1 ARHGAP17 DUSP10

3.35e-051921532de242d81dc085ae734eb7d1f091af9a542e0866
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SBK1 ARHGAP17 DUSP10

3.35e-05192153ba2a683472a8b785dbf666dc6e94356d879486c3
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SBK1 ARHGAP17 DUSP10

3.51e-05195153f5bf4797972185afa76638293166abd536e5472f
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SBK1 ARHGAP17 DUSP10

3.51e-05195153d77423d0ec64b397c6d1eec181c5fc0acaa92d63
ToppCellMS-IIF-Lymphocyte-T/NK-Treg|IIF / Disease, condition lineage and cell class

HECTD2 DUSP10 EIF3E

3.67e-051981537bbf8403ecf9f8e403b04f18d265ece977cc49e7
DiseaseDupuytren Contracture

DUSP10 EIF3E

1.35e-03108152EFO_0004229
Diseaseepilepsy (implicated_via_orthology)

KIF4A KIF4B

3.04e-03163152DOID:1826 (implicated_via_orthology)
Diseasetonsillectomy risk measurement

SBK1 DUSP10

7.53e-03260152EFO_0007924
Diseaseamyloid-beta measurement

KCNV1 DUSP10

1.37e-02355152EFO_0005194
Diseasecoronary artery disease

SBK1 BMP1 KIF4B

2.09e-021194153EFO_0001645

Protein segments in the cluster

PeptideGeneStartEntry
FQTFEVEEETDCGYD

BMP1

906

P13497
PDEFDDFVTYEANEV

RAB11FIP3

291

O75154
VEEDFYSTFQVFQEE

HECTD2

576

Q5U5R9
YFEEAFEFIEEAHQC

DUSP10

386

Q9Y6W6
CDDANPVDNEYFFDR

KCNV1

91

Q6PIU1
APEFPRFYEAFVCEN

CDH20

491

Q9HBT6
PITEFVECLYVNFDF

EIF3E

291

P60228
YCEFDDQEVFVEVYN

GNS

466

P15586
YDFVFDPSTEQEEVF

KIF4A

51

O95239
YDFVFDPCTEQEEVF

KIF4B

51

Q2VIQ3
VVFETEDCYVFAQEY

SBK1

116

Q52WX2
PEAYEFFFCDTIEEN

PERM1

581

Q5SV97
FFPEEVEFNVSEAFV

ARHGAP17

441

Q68EM7
PCFYQDFSVDIPVEF

SCAMP1

131

O15126
YVCQFPDQEEVRLFF

MPL

91

P40238