Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionfrizzled binding

WNT3 WNT5A WNT6 WNT2B WNT5B LRP6

1.28e-07421136GO:0005109
GeneOntologyMolecularFunctionzinc ion binding

TRIM51 ENPP2 UBR4 NSD1 AIRE TRIM54 ZNF407 ADH1A ADH1B ADH1C ATXN7L3 NFX1 NFXL1 ZFR NR3C2 TRIM50 HERC2 MNAT1 TRIM51G

5.79e-0789111319GO:0008270
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor activity

VLDLR LRP8 LRP2 LRP6

1.68e-06161134GO:0005041
GeneOntologyMolecularFunctionethanol binding

ADH1A ADH1B ADH1C

3.49e-0661133GO:0035276
GeneOntologyMolecularFunctionapolipoprotein binding

VLDLR LRP8 LRP4 LRP6

4.39e-06201134GO:0034185
GeneOntologyMolecularFunctionlipoprotein particle receptor activity

VLDLR LRP8 LRP2 LRP6

5.40e-06211134GO:0030228
GeneOntologyMolecularFunctioncargo receptor activity

VLDLR ENPP2 ITGB2 LRP8 LRP2 LRP6

8.74e-06851136GO:0038024
GeneOntologyMolecularFunctiontransition metal ion binding

TRIM51 ENPP2 UBR4 NSD1 AIRE TRIM54 ZNF407 ADH1A ADH1B ADH1C ATXN7L3 FDX1 NFX1 NFXL1 ZFR NR3C2 TRIM50 HERC2 MNAT1 TRIM51G

1.05e-05118911320GO:0046914
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

NSD1 ZNF300 AIRE ZNF302 ZNF883 ZNF529 ZNF518A ZNF710 ZNF707 ZNF250 BPTF ZSCAN32 ZNF776 ZNF394 WIZ MZF1 ZNF516 NFX1 NFXL1 NR3C2 PRDM14 ZNF572

1.99e-05145911322GO:0000977
GeneOntologyMolecularFunctionreelin receptor activity

VLDLR LRP8

3.17e-0521132GO:0038025
GeneOntologyMolecularFunctionextracellular matrix structural constituent

VWF LAMA1 LAMA3 LAMB2 SSPOP FBLN1 MUC5AC

9.77e-051881137GO:0005201
GeneOntologyMolecularFunctionvery-low-density lipoprotein particle receptor activity

VLDLR LRP8

1.89e-0441132GO:0030229
GeneOntologyMolecularFunctionperoxisome proliferator activated receptor binding

ASXL1 ASXL3 ASXL2

2.18e-04211133GO:0042975
GeneOntologyMolecularFunctionribose phosphate diphosphokinase activity

PRPS2 PRPS1

3.14e-0451132GO:0004749
GeneOntologyMolecularFunctioncalcium ion binding

VLDLR DSG2 ENPP2 SVEP1 LRP8 FBLN1 HEG1 MEGF6 SCUBE3 LRP2 LRP4 EGFLAM NOTCH2

3.19e-0474911313GO:0005509
GeneOntologyMolecularFunctionall-trans-retinol dehydrogenase (NAD+) activity

ADH1A ADH1B ADH1C

3.28e-04241133GO:0004745
GeneOntologyMolecularFunctionalcohol dehydrogenase (NAD+) activity

ADH1A ADH1B ADH1C

4.17e-04261133GO:0004022
GeneOntologyMolecularFunctiondiphosphotransferase activity

PRPS2 PRPS1

4.69e-0461132GO:0016778
GeneOntologyMolecularFunctionalcohol dehydrogenase [NAD(P)+] activity

ADH1A ADH1B ADH1C

6.41e-04301133GO:0018455
GeneOntologyMolecularFunctionNAD binding

ADH1A ADH1B ADH1C ZC3HAV1

7.84e-04731134GO:0051287
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

NSD1 ZNF300 ZNF302 ZNF883 ZNF710 ZNF707 ZNF250 BPTF ZSCAN32 ZNF776 ZNF394 WIZ MZF1 ZNF516 NR3C2 NOTCH2 ZNF572

7.85e-04127111317GO:0000987
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

ZNF300 ZNF302 ZNF883 ZNF529 ZNF518A ZNF707 ZNF250 ZSCAN32 ZNF776 ZNF394 WIZ MZF1 ZNF516 NFX1 NFXL1 NR3C2 NOTCH2 ZNF572

9.48e-04141211318GO:0000981
GeneOntologyMolecularFunctionubiquitin protein ligase activity

TRIM51 UBR4 TRIM54 NFX1 TRIM50 HERC2 LONRF3 TRIM51G

1.26e-033721138GO:0061630
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

NSD1 ZNF300 ZNF302 ZNF883 ZNF710 ZNF707 ZNF250 BPTF ZSCAN32 ZNF776 ZNF394 WIZ MZF1 ZNF516 NR3C2 ZNF572

1.70e-03124411316GO:0000978
GeneOntologyMolecularFunctionubiquitin-like protein ligase activity

TRIM51 UBR4 TRIM54 NFX1 TRIM50 HERC2 LONRF3 TRIM51G

1.93e-033981138GO:0061659
GeneOntologyMolecularFunctionubiquitin-like protein transferase activity

TRIM51 UBR4 TRIM54 NFX1 TRIM50 HERC2 LONRF3 TRIM51G RNF212B

2.52e-035121139GO:0019787
GeneOntologyMolecularFunctionintegrin binding

VWF LAMB2 ITGB2 SVEP1 FBLN1

3.20e-031751135GO:0005178
GeneOntologyMolecularFunctionaminoacyltransferase activity

TRIM51 UBR4 TRIM54 NFX1 TRIM50 HERC2 LONRF3 TRIM51G RNF212B

3.26e-035321139GO:0016755
GeneOntologyBiologicalProcessresponse to retinoic acid

ASXL1 WNT3 WNT5A WNT6 TEK ADH1A ADH1B ADH1C WNT5B

3.73e-081311119GO:0032526
GeneOntologyBiologicalProcessacetaldehyde biosynthetic process

ADH1A ADH1B ADH1C

1.52e-0731113GO:0046186
GeneOntologyBiologicalProcessacetaldehyde metabolic process

ADH1A ADH1B ADH1C

1.51e-0651113GO:0006117
GeneOntologyBiologicalProcessnegative regulation of fibroblast growth factor receptor signaling pathway

SPRY3 WNT5A SPRY4 PRDM14

1.27e-05271114GO:0040037
GeneOntologyBiologicalProcessglomerular epithelial cell development

ASXL1 LAMB2 NOTCH2

1.77e-05101113GO:0072310
GeneOntologyBiologicalProcesspodocyte development

ASXL1 LAMB2 NOTCH2

1.77e-05101113GO:0072015
GeneOntologyBiologicalProcesscell morphogenesis

SPRY3 SEMA4D VLDLR ASXL1 ENPP2 WNT3 WNT5A LAMA1 LAMA3 LAMB2 ITGB2 LRP8 MET HEG1 LRP2 LRP4 LRP6 PRDM14 NOTCH2

1.92e-05119411119GO:0000902
GeneOntologyBiologicalProcesslymph circulation

SVEP1 HEG1

2.87e-0521112GO:0003017
GeneOntologyBiologicalProcessnegative regulation of transforming growth factor beta production

MET FBLN1 FURIN

3.22e-05121113GO:0071635
GeneOntologyBiologicalProcessmesenchymal-epithelial cell signaling

WNT5A WNT2B MET

3.22e-05121113GO:0060638
GeneOntologyBiologicalProcesskidney development

ASXL1 WNT5A WNT6 WNT2B LAMB2 TEK SLC12A1 LRP2 LRP4 NOTCH2

3.31e-0537211110GO:0001822
GeneOntologyBiologicalProcessregulation of protein phosphorylation

SPRY3 SEMA4D VLDLR ENPP2 WNT5A NSD1 TEK ITGB2 LRP8 MET FBLN1 HEG1 DNAJC10 SPRY4 LRP4 LRP6 MNAT1 NOTCH2

3.35e-05113311118GO:0001932
GeneOntologyBiologicalProcessanimal organ morphogenesis

ASXL1 WNT3 WNT5A WNT6 WNT2B LAMA1 LAMA3 LAMB2 TEK WNT5B MET HEG1 ASXL3 LRP2 LRP4 LRP6 ASXL2 MEGF11 NOTCH2

4.43e-05126911119GO:0009887
GeneOntologyBiologicalProcessrenal system development

ASXL1 WNT5A WNT6 WNT2B LAMB2 TEK SLC12A1 LRP2 LRP4 NOTCH2

4.51e-0538611110GO:0072001
GeneOntologyBiologicalProcessregulation of morphogenesis of an epithelium

WNT5A WNT2B WNT5B MET LRP6

5.62e-05761115GO:1905330
GeneOntologyBiologicalProcesscell-substrate adhesion

VWF TRIP6 ENPP2 LAMB2 TEK ITGB2 SVEP1 FBLN1 SPRY4 EGFLAM

7.46e-0541011110GO:0031589
GeneOntologyBiologicalProcessnon-canonical Wnt signaling pathway involved in heart development

WNT5A LRP6

8.58e-0531112GO:0061341
GeneOntologyBiologicalProcessregulation of fibroblast growth factor receptor signaling pathway

SPRY3 WNT5A SPRY4 PRDM14

9.13e-05441114GO:0040036
GeneOntologyBiologicalProcessregulation of phosphorylation

SPRY3 SEMA4D VLDLR ENPP2 WNT5A NSD1 TEK ITGB2 LRP8 MET FBLN1 HEG1 DNAJC10 SPRY4 LRP4 LRP6 MNAT1 NOTCH2

9.28e-05122611118GO:0042325
GeneOntologyBiologicalProcessbehavioral response to ethanol

ADH1A ADH1B ADH1C

9.76e-05171113GO:0048149
GeneOntologyBiologicalProcessethanol catabolic process

ADH1A ADH1B ADH1C

9.76e-05171113GO:0006068
GeneOntologyBiologicalProcessbranching morphogenesis of an epithelial tube

WNT5A WNT6 WNT2B LAMA1 TEK MET LRP6

9.88e-051981117GO:0048754
GeneOntologyBiologicalProcesscamera-type eye development

WNT5A WNT6 WNT2B LAMA1 LAMB2 WNT5B KMT2C LRP6 MEGF11 NOTCH2

1.02e-0442611110GO:0043010
GeneOntologyBiologicalProcessmidbrain dopaminergic neuron differentiation

WNT3 WNT5A LRP6

1.17e-04181113GO:1904948
GeneOntologyBiologicalProcessethanol metabolic process

ADH1A ADH1B ADH1C

1.17e-04181113GO:0006067
GeneOntologyBiologicalProcessretinoid metabolic process

ADH1A LRP8 ADH1B ADH1C LRP2

1.19e-04891115GO:0001523
GeneOntologyBiologicalProcessplasma membrane bounded cell projection morphogenesis

SPRY3 SEMA4D VLDLR ENPP2 WNT3 WNT5A LAMA1 LAMA3 LAMB2 LRP8 MET LRP2 LRP4 NOTCH2

1.28e-0481911114GO:0120039
GeneOntologyBiologicalProcessconvergent extension

WNT5A WNT5B LRP6

1.38e-04191113GO:0060026
GeneOntologyBiologicalProcesscell projection morphogenesis

SPRY3 SEMA4D VLDLR ENPP2 WNT3 WNT5A LAMA1 LAMA3 LAMB2 LRP8 MET LRP2 LRP4 NOTCH2

1.40e-0482611114GO:0048858
GeneOntologyBiologicalProcessditerpenoid metabolic process

ADH1A LRP8 ADH1B ADH1C LRP2

1.55e-04941115GO:0016101
GeneOntologyBiologicalProcessaxon guidance

SEMA4D WNT3 WNT5A LAMA1 LAMA3 LAMB2 LRP2 NOTCH2

1.56e-042851118GO:0007411
GeneOntologyBiologicalProcessneuron projection guidance

SEMA4D WNT3 WNT5A LAMA1 LAMA3 LAMB2 LRP2 NOTCH2

1.59e-042861118GO:0097485
GeneOntologyBiologicalProcessWnt signaling pathway involved in heart development

WNT5A LRP6

1.71e-0441112GO:0003306
GeneOntologyBiologicalProcesstissue morphogenesis

WNT3 WNT5A WNT6 WNT2B LAMA1 AIRE TEK WNT5B MET HEG1 LRP2 LRP6 NOTCH2

1.98e-0475011113GO:0048729
GeneOntologyBiologicalProcesspodocyte differentiation

ASXL1 LAMB2 NOTCH2

2.17e-04221113GO:0072112
GeneOntologyBiologicalProcessglomerular epithelial cell differentiation

ASXL1 LAMB2 NOTCH2

2.17e-04221113GO:0072311
GeneOntologyBiologicalProcessrenal filtration cell differentiation

ASXL1 LAMB2 NOTCH2

2.17e-04221113GO:0061318
GeneOntologyBiologicalProcesscardiac chamber morphogenesis

WNT5A TEK HEG1 LRP2 LRP6 NOTCH2

2.37e-041611116GO:0003206
GeneOntologyBiologicalProcessprimary alcohol catabolic process

ADH1A ADH1B ADH1C

2.48e-04231113GO:0034310
GeneOntologyBiologicalProcessglomerular epithelium development

ASXL1 LAMB2 NOTCH2

2.48e-04231113GO:0072010
GeneOntologyBiologicalProcessterpenoid metabolic process

ADH1A LRP8 ADH1B ADH1C LRP2

2.60e-041051115GO:0006721
GeneOntologyBiologicalProcesseye development

WNT5A WNT6 WNT2B LAMA1 LAMB2 WNT5B KMT2C LRP6 MEGF11 NOTCH2

2.68e-0448011110GO:0001654
GeneOntologyBiologicalProcessvisual system development

WNT5A WNT6 WNT2B LAMA1 LAMB2 WNT5B KMT2C LRP6 MEGF11 NOTCH2

2.82e-0448311110GO:0150063
GeneOntologyBiologicalProcessTie signaling pathway

TEK SVEP1

2.84e-0451112GO:0048014
GeneOntologyBiologicalProcesschemoattraction of axon

WNT5A LRP2

2.84e-0451112GO:0061642
GeneOntologyBiologicalProcessmorphogenesis of a branching epithelium

WNT5A WNT6 WNT2B LAMA1 TEK MET LRP6

2.91e-042361117GO:0061138
GeneOntologyBiologicalProcesssubstrate adhesion-dependent cell spreading

ENPP2 LAMB2 TEK FBLN1 SPRY4

3.09e-041091115GO:0034446
GeneOntologyBiologicalProcesssensory system development

WNT5A WNT6 WNT2B LAMA1 LAMB2 WNT5B KMT2C LRP6 MEGF11 NOTCH2

3.21e-0449111110GO:0048880
GeneOntologyBiologicalProcessheart morphogenesis

ASXL1 WNT5A TEK HEG1 LRP2 LRP6 ASXL2 NOTCH2

3.47e-043211118GO:0003007
GeneOntologyBiologicalProcessnephron development

ASXL1 WNT6 WNT2B LAMB2 TEK NOTCH2

3.60e-041741116GO:0072006
GeneOntologyBiologicalProcessaxis specification

WNT3 WNT5A WNT6 LRP6 NOTCH2

3.65e-041131115GO:0009798
GeneOntologyBiologicalProcessneuron projection morphogenesis

SPRY3 SEMA4D VLDLR WNT3 WNT5A LAMA1 LAMA3 LAMB2 LRP8 MET LRP2 LRP4 NOTCH2

3.77e-0480211113GO:0048812
GeneOntologyBiologicalProcessregulation of cellular response to growth factor stimulus

SPRY3 WNT5A TEK FURIN SPRY4 SCUBE3 LRP2 PRDM14 NOTCH2

3.89e-044121119GO:0090287
GeneOntologyBiologicalProcess5-phosphoribose 1-diphosphate metabolic process

PRPS2 PRPS1

4.24e-0461112GO:0046391
GeneOntologyBiologicalProcess5-phosphoribose 1-diphosphate biosynthetic process

PRPS2 PRPS1

4.24e-0461112GO:0006015
GeneOntologyBiologicalProcessregulation of small GTPase mediated signal transduction

SPRY3 SEMA4D TEK MET HEG1 SPRY4 LRP4 NOTCH2

4.43e-043331118GO:0051056
GeneOntologyBiologicalProcesspericardium development

WNT5A HEG1 LRP6

4.50e-04281113GO:0060039
GeneOntologyBiologicalProcessepithelial tube morphogenesis

WNT5A WNT6 WNT2B LAMA1 TEK MET LRP2 LRP6 NOTCH2

4.55e-044211119GO:0060562
GeneOntologyBiologicalProcessnegative regulation of small GTPase mediated signal transduction

SPRY3 MET HEG1 SPRY4

4.69e-04671114GO:0051058
GeneOntologyBiologicalProcessmorphogenesis of a branching structure

WNT5A WNT6 WNT2B LAMA1 TEK MET LRP6

4.97e-042581117GO:0001763
GeneOntologyBiologicalProcessmorphogenesis of an epithelium

WNT5A WNT6 WNT2B LAMA1 AIRE TEK WNT5B MET LRP2 LRP6 NOTCH2

5.10e-0461911111GO:0002009
GeneOntologyBiologicalProcessregulation of phosphate metabolic process

SPRY3 SEMA4D VLDLR ENPP2 WNT5A NSD1 TEK ITGB2 LRP8 MET FBLN1 HEG1 DNAJC10 SPRY4 LRP4 LRP6 MNAT1 NOTCH2

5.65e-04142111118GO:0019220
GeneOntologyBiologicalProcessregulation of phosphorus metabolic process

SPRY3 SEMA4D VLDLR ENPP2 WNT5A NSD1 TEK ITGB2 LRP8 MET FBLN1 HEG1 DNAJC10 SPRY4 LRP4 LRP6 MNAT1 NOTCH2

5.74e-04142311118GO:0051174
GeneOntologyBiologicalProcessaldehyde biosynthetic process

ADH1A ADH1B ADH1C

6.11e-04311113GO:0046184
GeneOntologyBiologicalProcessepithelial cell development

ASXL1 WNT5A LAMB2 WNT5B MET HEG1 NOTCH2

6.36e-042691117GO:0002064
GeneOntologyBiologicalProcessembryo development

TRIP6 WNT3 WNT5A WNT6 WNT2B LAMA1 NSD1 LAMA3 WNT5B BPTF HEG1 FURIN LRP2 LRP4 LRP6 ASXL2 PRDM14 NOTCH2

6.44e-04143711118GO:0009790
GeneOntologyBiologicalProcessnephron epithelium development

ASXL1 WNT6 WNT2B LAMB2 NOTCH2

6.45e-041281115GO:0072009
GeneOntologyBiologicalProcesscellular response to retinoic acid

WNT3 WNT5A WNT6 WNT5B

6.50e-04731114GO:0071300
GeneOntologyBiologicalProcesspositive regulation of neurogenesis

SEMA4D ENPP2 WNT3 WNT5A LRP8 MET LRP2 NOTCH2

6.62e-043541118GO:0050769
GeneOntologyBiologicalProcessregulation of non-canonical Wnt signaling pathway

WNT5A WNT5B LRP6

6.71e-04321113GO:2000050
GeneOntologyBiologicalProcessmorphogenesis of an epithelial sheet

WNT5A LAMA1 LRP6 NOTCH2

6.84e-04741114GO:0002011
GeneOntologyBiologicalProcesscell morphogenesis involved in neuron differentiation

SEMA4D VLDLR WNT3 WNT5A LAMA1 LAMA3 LAMB2 LRP8 MET LRP2 LRP4 NOTCH2

7.01e-0474811112GO:0048667
GeneOntologyBiologicalProcessdendrite morphogenesis

SEMA4D VLDLR WNT5A LRP8 MET LRP4

7.12e-041981116GO:0048813
GeneOntologyBiologicalProcessreelin-mediated signaling pathway

VLDLR LRP8

7.87e-0481112GO:0038026
GeneOntologyBiologicalProcesscardiac septum development

WNT5A HEG1 LRP2 LRP6 NOTCH2

7.93e-041341115GO:0003279
GeneOntologyBiologicalProcessglomerulus development

ASXL1 LAMB2 TEK NOTCH2

7.95e-04771114GO:0032835
GeneOntologyBiologicalProcesscardiac muscle tissue morphogenesis

WNT5A HEG1 LRP2 LRP6

7.95e-04771114GO:0055008
GeneOntologyBiologicalProcessgastrulation with mouth forming second

WNT5A NSD1 LRP6

8.76e-04351113GO:0001702
GeneOntologyBiologicalProcesscardiac atrium morphogenesis

WNT5A HEG1 NOTCH2

8.76e-04351113GO:0003209
GeneOntologyBiologicalProcessnegative regulation of protein phosphorylation

SPRY3 SEMA4D MET FBLN1 HEG1 DNAJC10 SPRY4 LRP6

9.61e-043751118GO:0001933
GeneOntologyBiologicalProcessregulation of protein modification process

SPRY3 SEMA4D VLDLR ENPP2 WNT5A NSD1 TEK ITGB2 LRP8 MET FBLN1 HEG1 DNAJC10 SPRY4 LRP4 LRP6 MNAT1 NOTCH2

9.64e-04148811118GO:0031399
GeneOntologyBiologicalProcesspericardium morphogenesis

WNT5A LRP6

1.01e-0391112GO:0003344
GeneOntologyBiologicalProcesscell surface receptor signaling pathway involved in heart development

WNT5A LRP6

1.01e-0391112GO:0061311
GeneOntologyBiologicalProcessnegative regulation of morphogenesis of an epithelium

WNT5A LRP6

1.01e-0391112GO:1905331
GeneOntologyBiologicalProcesscardiac chamber development

WNT5A TEK HEG1 LRP2 LRP6 NOTCH2

1.02e-032121116GO:0003205
GeneOntologyBiologicalProcessregulation of transforming growth factor beta production

MET FBLN1 FURIN

1.03e-03371113GO:0071634
GeneOntologyBiologicalProcessisoprenoid metabolic process

ADH1A LRP8 ADH1B ADH1C LRP2

1.10e-031441115GO:0006720
GeneOntologyBiologicalProcessneuron projection arborization

SPRY3 WNT5A LRP2

1.12e-03381113GO:0140058
GeneOntologyBiologicalProcessribonucleoside monophosphate biosynthetic process

PRPS2 PPAT PRPS1

1.12e-03381113GO:0009156
GeneOntologyBiologicalProcessregulation of kinase activity

SPRY3 VLDLR WNT5A TEK LRP8 MET HEG1 SPRY4 LRP6 MNAT1 NOTCH2

1.18e-0368611111GO:0043549
GeneOntologyBiologicalProcessembryonic limb morphogenesis

WNT3 WNT5A LRP4 LRP6 NOTCH2

1.24e-031481115GO:0030326
GeneOntologyBiologicalProcessembryonic appendage morphogenesis

WNT3 WNT5A LRP4 LRP6 NOTCH2

1.24e-031481115GO:0035113
GeneOntologyBiologicalProcessregulation of cell morphogenesis

SPRY3 SEMA4D ENPP2 WNT5A ITGB2 LRP8 MET

1.25e-033021117GO:0022604
GeneOntologyBiologicalProcesspurine nucleobase biosynthetic process

PPAT PRPS1

1.26e-03101112GO:0009113
GeneOntologyBiologicalProcesstransforming growth factor beta production

MET FBLN1 FURIN

1.30e-03401113GO:0071604
GeneOntologyBiologicalProcessamyloid-beta clearance

ITGB2 LRP2 LRP4

1.30e-03401113GO:0097242
GeneOntologyBiologicalProcessretinoic acid metabolic process

ADH1A ADH1B ADH1C

1.30e-03401113GO:0042573
GeneOntologyBiologicalProcessregulation of dendrite development

SEMA4D VLDLR WNT5A LRP8 MET

1.31e-031501115GO:0050773
GeneOntologyBiologicalProcessnegative regulation of cellular response to growth factor stimulus

SPRY3 WNT5A SPRY4 LRP2 PRDM14

1.31e-031501115GO:0090288
GeneOntologyBiologicalProcesscardiac septum morphogenesis

WNT5A LRP2 LRP6 NOTCH2

1.36e-03891114GO:0060411
GeneOntologyCellularComponentlaminin-3 complex

LAMA1 LAMA3 LAMB2

1.58e-0731143GO:0005608
GeneOntologyCellularComponentcell surface

VLDLR VWF DSG2 WNT5A WNT6 NEU3 ADAM29 TEK ITGB2 LRP8 WNT5B MET HEG1 SLC12A1 FURIN CLEC4G SCUBE3 LRP2 LRP4 LRP6 NOTCH2

5.42e-07111111421GO:0009986
GeneOntologyCellularComponentextracellular matrix

VWF WNT3 WNT5A WNT6 WNT2B LAMA1 LAMA3 LAMB2 SSPOP SVEP1 ADAMTS10 WNT5B FBLN1 MEGF6 EGFLAM MUC5AC

5.48e-0765611416GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

VWF WNT3 WNT5A WNT6 WNT2B LAMA1 LAMA3 LAMB2 SSPOP SVEP1 ADAMTS10 WNT5B FBLN1 MEGF6 EGFLAM MUC5AC

5.70e-0765811416GO:0030312
GeneOntologyCellularComponentPR-DUB complex

ASXL1 ASXL3 ASXL2

6.29e-0741143GO:0035517
GeneOntologyCellularComponentlaminin complex

LAMA1 LAMA3 LAMB2

1.84e-05101143GO:0043256
GeneOntologyCellularComponentGolgi lumen

WNT3 WNT5A WNT6 WNT5B FURIN MUC5AC

2.96e-051091146GO:0005796
GeneOntologyCellularComponentcollagen-containing extracellular matrix

VWF WNT5A WNT2B LAMA1 LAMA3 LAMB2 SSPOP ADAMTS10 WNT5B FBLN1 MEGF6 EGFLAM

3.29e-0553011412GO:0062023
GeneOntologyCellularComponentESCRT-0 complex

STAM2 STAM

8.81e-0531142GO:0033565
GeneOntologyCellularComponentribose phosphate diphosphokinase complex

PRPS2 PRPS1

2.92e-0451142GO:0002189
GeneOntologyCellularComponentprotein complex involved in cell adhesion

LAMA1 LAMB2 ITGB2 PLP1

3.03e-04591144GO:0098636
GeneOntologyCellularComponentbasement membrane

LAMA1 LAMA3 LAMB2 FBLN1 EGFLAM

5.51e-041221145GO:0005604
GeneOntologyCellularComponentplasma membrane raft

NEU3 ITGB2 LRP8 LRP4 LRP6

1.28e-031471145GO:0044853
GeneOntologyCellularComponentreceptor complex

SEMA4D VLDLR TEK ITGB2 LRP8 MET LRP2 NR3C2 PLP1 NOTCH2

1.30e-0358111410GO:0043235
GeneOntologyCellularComponentendoplasmic reticulum lumen

WNT3 WNT5A WNT6 LAMB2 WNT5B DNAJC10 FURIN

2.31e-033321147GO:0005788
GeneOntologyCellularComponentPcG protein complex

ASXL1 ASXL3 ASXL2

2.87e-03521143GO:0031519
MousePhenoabnormal ethanol metabolism

ADH1A ADH1B ADH1C

4.13e-066843MP:0005443
MousePhenoabnormal retinol metabolism

ADH1A ADH1B ADH1C

7.20e-067843MP:0005444
MousePhenoabnormal vitamin metabolism

ADH1A ADH1B ADH1C

9.04e-0515843MP:0013244
MousePhenoabnormal vitamin or vitamin cofactor metabolism

ADH1A ADH1B ADH1C

9.04e-0515843MP:0013274
MousePhenoabnormal vitamin A metabolism

ADH1A ADH1B ADH1C

9.04e-0515843MP:0011233
MousePhenoenhanced behavioral response to alcohol

ADH1A ADH1B ADH1C

1.11e-0416843MP:0009751
DomainEGF_1

VLDLR LAMA1 LAMA3 LAMB2 ADAM29 TEK SSPOP ITGB2 SVEP1 LRP8 FBLN1 HEG1 MEGF6 SCUBE3 LRP2 LRP4 LRP6 EGFLAM MEGF11 NOTCH2

4.25e-1725511120PS00022
DomainEGF_2

VLDLR LAMA1 LAMA3 LAMB2 ADAM29 TEK SSPOP ITGB2 SVEP1 LRP8 FBLN1 HEG1 MEGF6 SCUBE3 LRP2 LRP4 LRP6 EGFLAM MEGF11 NOTCH2

9.02e-1726511120PS01186
DomainEGF-like_CS

VLDLR LAMA1 LAMA3 LAMB2 ADAM29 TEK ITGB2 SVEP1 LRP8 FBLN1 HEG1 MEGF6 SCUBE3 LRP2 LRP4 LRP6 EGFLAM MEGF11 NOTCH2

1.11e-1526111119IPR013032
DomainEGF-like_dom

VLDLR LAMA1 LAMA3 LAMB2 ADAM29 TEK SVEP1 LRP8 FBLN1 HEG1 MEGF6 SCUBE3 LRP2 LRP4 LRP6 EGFLAM MEGF11 NOTCH2

7.55e-1524911118IPR000742
DomainEGF

VLDLR LAMA1 LAMA3 LAMB2 TEK SVEP1 LRP8 FBLN1 HEG1 MEGF6 SCUBE3 LRP2 LRP4 LRP6 EGFLAM MEGF11 NOTCH2

4.44e-1423511117SM00181
DomainGrowth_fac_rcpt_

VLDLR LAMA1 LAMA3 LAMB2 TEK SVEP1 LRP8 FBLN1 MEGF6 FURIN SCUBE3 LRP2 LRP4 NOTCH2

4.66e-1315611114IPR009030
DomainEGF_3

VLDLR ADAM29 TEK SSPOP SVEP1 LRP8 FBLN1 HEG1 MEGF6 SCUBE3 LRP2 LRP4 LRP6 EGFLAM MEGF11 NOTCH2

6.69e-1323511116PS50026
DomainEGF_CA

VLDLR SVEP1 LRP8 FBLN1 HEG1 MEGF6 SCUBE3 LRP2 LRP4 NOTCH2

8.84e-118611110PF07645
DomainEGF_CA

VLDLR SVEP1 LRP8 FBLN1 HEG1 MEGF6 SCUBE3 LRP2 LRP4 EGFLAM NOTCH2

1.60e-1012211111SM00179
DomainEGF-like_Ca-bd_dom

VLDLR SVEP1 LRP8 FBLN1 HEG1 MEGF6 SCUBE3 LRP2 LRP4 EGFLAM NOTCH2

1.90e-1012411111IPR001881
DomainEGF

VLDLR SVEP1 LRP8 HEG1 MEGF6 SCUBE3 LRP2 LRP4 LRP6 EGFLAM NOTCH2

2.26e-1012611111PF00008
DomainEGF_Ca-bd_CS

VLDLR SVEP1 LRP8 FBLN1 HEG1 MEGF6 SCUBE3 LRP2 LRP4 NOTCH2

2.97e-109711110IPR018097
DomainEGF_CA

VLDLR SVEP1 LRP8 FBLN1 HEG1 MEGF6 SCUBE3 LRP2 LRP4 NOTCH2

3.65e-109911110PS01187
DomainASX_HYDROXYL

VLDLR SVEP1 LRP8 FBLN1 HEG1 MEGF6 SCUBE3 LRP2 LRP4 NOTCH2

4.03e-1010011110PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

VLDLR SVEP1 LRP8 FBLN1 HEG1 MEGF6 SCUBE3 LRP2 LRP4 NOTCH2

7.20e-1010611110IPR000152
DomainLdl_recept_b

VLDLR LRP8 LRP2 LRP4 LRP6

1.30e-08141115PF00058
DomainLDLRB

VLDLR LRP8 LRP2 LRP4 LRP6

1.30e-08141115PS51120
DomainLY

VLDLR LRP8 LRP2 LRP4 LRP6

1.94e-08151115SM00135
DomainLDLR_classB_rpt

VLDLR LRP8 LRP2 LRP4 LRP6

1.94e-08151115IPR000033
DomainZINC_FINGER_C2H2_1

ZNF300 ZNF407 ZNF233 ZNF302 ZNF883 ZNF529 ZNF518A ZNF710 ZNF707 ZNF250 ZSCAN32 ZNF776 ZNF394 WIZ MZF1 ZNF516 ZFR PRDM14 ZNF222 ZNF572

2.85e-0877711120PS00028
DomainZnf_C2H2-like

ZNF300 ZNF407 ZNF233 ZNF302 ZNF883 ZNF529 ZNF518A ZNF710 ZNF707 ZNF250 ZSCAN32 ZNF776 ZNF394 WIZ MZF1 ZNF516 ZFR PRDM14 ZNF222 ZNF572

4.24e-0879611120IPR015880
DomainZnf_C2H2

ZNF300 ZNF407 ZNF233 ZNF302 ZNF883 ZNF529 ZNF518A ZNF710 ZNF707 ZNF250 ZSCAN32 ZNF776 ZNF394 WIZ MZF1 ZNF516 ZFR PRDM14 ZNF222 ZNF572

5.10e-0880511120IPR007087
DomainZnF_C2H2

ZNF300 ZNF407 ZNF233 ZNF302 ZNF883 ZNF529 ZNF518A ZNF710 ZNF707 ZNF250 ZSCAN32 ZNF776 ZNF394 WIZ MZF1 ZNF516 ZFR PRDM14 ZNF222 ZNF572

5.42e-0880811120SM00355
DomainWnt

WNT3 WNT5A WNT6 WNT2B WNT5B

7.37e-08191115IPR005817
DomainWnt_CS

WNT3 WNT5A WNT6 WNT2B WNT5B

7.37e-08191115IPR018161
Domainwnt

WNT3 WNT5A WNT6 WNT2B WNT5B

7.37e-08191115PF00110
DomainWNT1

WNT3 WNT5A WNT6 WNT2B WNT5B

7.37e-08191115SM00097
DomainWNT1

WNT3 WNT5A WNT6 WNT2B WNT5B

7.37e-08191115PS00246
DomainZF_PHD_2

ASXL1 PHF12 NSD1 AIRE BPTF KMT2C ASXL3 ASXL2

9.55e-08951118PS50016
DomainZF_PHD_1

ASXL1 PHF12 NSD1 AIRE BPTF KMT2C ASXL3 ASXL2

1.04e-07961118PS01359
DomainLDLR_class-A_CS

VLDLR SSPOP LRP8 LRP2 LRP4 LRP6

1.25e-07401116IPR023415
Domainzf-C2H2

ZNF300 ZNF407 ZNF233 ZNF302 ZNF883 ZNF529 ZNF518A ZNF710 ZNF707 ZNF250 ZSCAN32 ZNF776 ZNF394 MZF1 ZNF516 PRDM14 ZNF222 ZNF572

1.34e-0769311118PF00096
DomainZnf_C2H2/integrase_DNA-bd

ZNF300 ZNF407 ZNF233 ZNF302 ZNF883 ZNF529 ZNF518A ZNF710 ZNF707 ZNF250 ZSCAN32 ZNF776 ZNF394 MZF1 ZNF516 PRDM14 ZNF222 ZNF572

1.37e-0769411118IPR013087
DomainZINC_FINGER_C2H2_2

ZNF300 ZNF407 ZNF233 ZNF302 ZNF883 ZNF529 ZNF518A ZNF710 ZNF707 ZNF250 ZSCAN32 ZNF776 ZNF394 WIZ MZF1 ZNF516 PRDM14 ZNF222 ZNF572

1.42e-0777511119PS50157
DomainHARE-HTH

ASXL1 ASXL3 ASXL2

2.04e-0731113PF05066
DomainASXH

ASXL1 ASXL3 ASXL2

2.04e-0731113PF13919
DomainPHD_3

ASXL1 ASXL3 ASXL2

2.04e-0731113PF13922
DomainASX-like_PHD

ASXL1 ASXL3 ASXL2

2.04e-0731113IPR026905
DomainASX/ASX-like

ASXL1 ASXL3 ASXL2

2.04e-0731113IPR024811
DomainASXH

ASXL1 ASXL3 ASXL2

2.04e-0731113IPR028020
DomainHB1/Asxl_HTH

ASXL1 ASXL3 ASXL2

2.04e-0731113IPR007759
DomainLdl_recept_a

VLDLR SSPOP LRP8 LRP2 LRP4 LRP6

2.59e-07451116PF00057
Domain-

VLDLR SSPOP LRP8 LRP2 LRP4 LRP6

2.97e-074611164.10.400.10
DomainLDLRA_1

VLDLR SSPOP LRP8 LRP2 LRP4 LRP6

3.85e-07481116PS01209
DomainLDLRA_2

VLDLR SSPOP LRP8 LRP2 LRP4 LRP6

4.37e-07491116PS50068
DomainLDrepeatLR_classA_rpt

VLDLR SSPOP LRP8 LRP2 LRP4 LRP6

4.37e-07491116IPR002172
DomainLDLa

VLDLR SSPOP LRP8 LRP2 LRP4 LRP6

4.37e-07491116SM00192
Domain-

ZNF300 ZNF407 ZNF233 ZNF302 ZNF883 ZNF529 ZNF710 ZNF707 ZNF250 ZSCAN32 ZNF776 ZNF394 MZF1 ZNF516 PRDM14 ZNF222 ZNF572

5.21e-07679111173.30.160.60
DomainZnf_RING/FYVE/PHD

SPIRE2 TRIM51 PHF12 DTX3 NSD1 AIRE TRIM54 RNF17 BPTF KMT2C TRIM50 LONRF3 MNAT1 RNF212B

5.75e-0745911114IPR013083
DomainTIL_dom

VWF SSPOP LRP2 MUC5AC

1.13e-06141114IPR002919
DomainEGF_extracell

TEK ITGB2 SVEP1 MEGF6 LRP2 MEGF11

1.48e-06601116IPR013111
DomainEGF_2

TEK ITGB2 SVEP1 MEGF6 LRP2 MEGF11

1.48e-06601116PF07974
DomainLaminin_EGF

LAMA1 LAMA3 LAMB2 MEGF6 MEGF11

1.91e-06351115PF00053
DomainEGF_Lam

LAMA1 LAMA3 LAMB2 MEGF6 MEGF11

1.91e-06351115SM00180
DomainZinc_finger_PHD-type_CS

PHF12 NSD1 AIRE BPTF NFX1 NFXL1

2.39e-06651116IPR019786
Domain-

SPIRE2 TRIM51 PHF12 DTX3 NSD1 AIRE TRIM54 BPTF KMT2C TRIM50 LONRF3 MNAT1 RNF212B

2.66e-06449111133.30.40.10
DomainLaminin_EGF

LAMA1 LAMA3 LAMB2 MEGF6 MEGF11

2.91e-06381115IPR002049
Domain-

VLDLR LRP8 LRP2 LRP4 LRP6

3.32e-063911152.120.10.30
DomainZnf_RING

TRIM51 DTX3 NSD1 TRIM54 RNF17 KMT2C NFX1 NFXL1 TRIM50 LONRF3 MNAT1

3.88e-0632611111IPR001841
DomainZnf_RING_CS

TRIM51 DTX3 TRIM54 RNF17 TRIM50 LONRF3 MNAT1 RNF212B

5.84e-061631118IPR017907
DomainZnf_PHD-finger

PHF12 NSD1 AIRE BPTF KMT2C NFX1

7.51e-06791116IPR019787
Domain6-blade_b-propeller_TolB-like

VLDLR LRP8 LRP2 LRP4 LRP6

7.64e-06461115IPR011042
DomainZF_RING_1

TRIM51 DTX3 TRIM54 RNF17 NFX1 NFXL1 TRIM50 LONRF3 MNAT1 RNF212B

9.31e-0629111110PS00518
DomainADH_Zn_CS

ADH1A ADH1B ADH1C

1.12e-0581113IPR002328
DomainADH_ZINC

ADH1A ADH1B ADH1C

1.12e-0581113PS00059
DomainZF_RING_2

TRIM51 DTX3 TRIM54 RNF17 KMT2C NFX1 NFXL1 TRIM50 LONRF3 MNAT1

1.15e-0529811110PS50089
DomainRING

TRIM51 DTX3 NSD1 TRIM54 RNF17 KMT2C NFX1 TRIM50 LONRF3 MNAT1

1.40e-0530511110SM00184
DomaincEGF

FBLN1 SCUBE3 LRP2 LRP4

1.60e-05261114IPR026823
DomaincEGF

FBLN1 SCUBE3 LRP2 LRP4

1.60e-05261114PF12662
DomainZnf_PHD

ASXL1 PHF12 NSD1 AIRE BPTF KMT2C

1.70e-05911116IPR001965
DomainhEGF

SVEP1 MEGF6 MEGF11 NOTCH2

2.17e-05281114PF12661
DomainZnf_FYVE_PHD

SPIRE2 PHF12 NSD1 AIRE BPTF KMT2C PRDM14

2.78e-051471117IPR011011
DomainPribosyltran

PRPS2 PPAT PRPS1

3.26e-05111113PF00156
DomainTIL

VWF SSPOP MUC5AC

4.32e-05121113PF01826
DomainPRTase-like

PRPS2 PPAT PRPS1

4.32e-05121113IPR029057
DomainPRibTrfase_dom

PRPS2 PPAT PRPS1

4.32e-05121113IPR000836
Domain-

PRPS2 PPAT PRPS1

4.32e-051211133.40.50.2020
DomainC8

VWF SSPOP MUC5AC

4.32e-05121113PF08742
DomainKRAB

ZNF300 ZNF233 ZNF302 ZNF529 ZNF707 ZNF250 ZSCAN32 ZNF776 ZNF394 ZNF222

5.47e-0535811110PS50805
DomainUnchr_dom_Cys-rich

VWF SSPOP MUC5AC

5.59e-05131113IPR014853
DomainC8

VWF SSPOP MUC5AC

5.59e-05131113SM00832
DomainKRAB

ZNF300 ZNF233 ZNF302 ZNF529 ZNF707 ZNF250 ZSCAN32 ZNF776 ZNF394 ZNF222

7.20e-0537011110IPR001909
DomainPHD

PHF12 NSD1 AIRE BPTF KMT2C

8.39e-05751115PF00628
DomainZnF_NFX

NFX1 NFXL1

1.05e-0431112SM00438
DomainPRPP_SYNTHASE

PRPS2 PRPS1

1.05e-0431112PS00114
Domainzf-NF-X1

NFX1 NFXL1

1.05e-0431112PF01422
DomainZnf_NFX1

NFX1 NFXL1

1.05e-0431112IPR000967
DomainPRib_PP_synth_CS

PRPS2 PRPS1

1.05e-0431112IPR000842
DomainADH_N

ADH1A ADH1B ADH1C

1.08e-04161113PF08240
DomainVWD

VWF SSPOP MUC5AC

1.08e-04161113SM00216
DomainVWF_type-D

VWF SSPOP MUC5AC

1.08e-04161113IPR001846
DomainLaminin_N

LAMA1 LAMA3 LAMB2

1.08e-04161113IPR008211
DomainPKS_ER

ADH1A ADH1B ADH1C

1.08e-04161113SM00829
DomainLAMININ_NTER

LAMA1 LAMA3 LAMB2

1.08e-04161113PS51117
DomainVWFD

VWF SSPOP MUC5AC

1.08e-04161113PS51233
DomainLaminin_N

LAMA1 LAMA3 LAMB2

1.08e-04161113PF00055
DomainPKS_ER

ADH1A ADH1B ADH1C

1.08e-04161113IPR020843
DomainADH_N

ADH1A ADH1B ADH1C

1.08e-04161113IPR013154
DomainVWD

VWF SSPOP MUC5AC

1.08e-04161113PF00094
DomainLamNT

LAMA1 LAMA3 LAMB2

1.08e-04161113SM00136
PathwayWP_WNT_SIGNALING_IN_KIDNEY_DISEASE

WNT3 WNT5A WNT6 WNT2B WNT5B LRP6

6.77e-0836856M39699
PathwayKEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_WNT_ACYLATION

WNT3 WNT5A WNT6 WNT2B WNT5B

7.70e-0819855M47836
PathwayKEGG_MEDICUS_VARIANT_FZD7_OVEREXPRESSION_TO_WNT_SIGNALING_PATHWAY

WNT3 WNT5A WNT6 WNT2B WNT5B LRP6

8.04e-0837856M47411
PathwayWP_WNT_SIGNALING_IN_KIDNEY_DISEASE

WNT3 WNT5A WNT6 WNT2B WNT5B LRP4

2.36e-0744856MM15878
PathwayKEGG_MEDICUS_VARIANT_LRP6_OVEREXPRESSION_TO_WNT_SIGNALING_PATHWAY

WNT3 WNT5A WNT6 WNT2B WNT5B LRP6

2.71e-0745856M47412
PathwayKEGG_MEDICUS_REFERENCE_WNT_SIGNALING_PATHWAY

WNT3 WNT5A WNT6 WNT2B WNT5B LRP6

3.10e-0746856M47409
PathwayWP_PLEURAL_MESOTHELIOMA

ASXL1 WNT3 WNT5A WNT6 WNT2B LAMA1 LAMA3 LAMB2 TEK ITGB2 WNT5B MET KMT2C LRP6

3.31e-074398514M42563
PathwayREACTOME_WNT_LIGAND_BIOGENESIS_AND_TRAFFICKING

WNT3 WNT5A WNT6 WNT2B WNT5B

3.42e-0725855MM14940
PathwayREACTOME_WNT_LIGAND_BIOGENESIS_AND_TRAFFICKING

WNT3 WNT5A WNT6 WNT2B WNT5B

4.21e-0726855M27239
PathwayKEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_WNT_INHIBITOR

WNT3 WNT5A WNT6 WNT2B WNT5B

6.24e-0728855M47835
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PTCH1_TO_HEDGEHOG_SIGNALING_PATHWAY

WNT3 WNT5A WNT6 WNT2B WNT5B

7.50e-0729855M47372
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_SMO_TO_HEDGEHOG_SIGNALING_PATHWAY

WNT3 WNT5A WNT6 WNT2B WNT5B

7.50e-0729855M47377
PathwayKEGG_HEDGEHOG_SIGNALING_PATHWAY

WNT3 WNT5A WNT6 WNT2B WNT5B LRP2

1.03e-0656856M1053
PathwayWP_OSTEOBLAST_DIFFERENTIATION_AND_RELATED_DISEASES

WNT3 WNT5A WNT6 WNT2B WNT5B LRP6 NOTCH2

6.93e-06118857M39852
PathwayREACTOME_SIGNALING_BY_MET

STAM2 LAMA1 LAMA3 LAMB2 STAM MET

7.86e-0679856M27643
PathwayREACTOME_ABACAVIR_ADME

ADH1A ADH1B ADH1C

1.16e-058853MM14869
PathwayWP_NCRNAS_INVOLVED_IN_WNT_SIGNALING_IN_HEPATOCELLULAR_CARCINOMA

WNT3 WNT5A WNT6 WNT2B WNT5B LRP6

1.57e-0589856M39563
PathwayWNT_SIGNALING

WNT3 WNT5A WNT6 WNT2B WNT5B LRP6

1.57e-0589856M5493
PathwayKEGG_BASAL_CELL_CARCINOMA

WNT3 WNT5A WNT6 WNT2B WNT5B

1.94e-0555855M17807
PathwayWP_FATTY_ACID_OMEGAOXIDATION

ADH1A ADH1B ADH1C

2.46e-0510853MM15833
PathwayWP_LNCRNA_IN_CANONICAL_WNT_SIGNALING_AND_COLORECTAL_CANCER

WNT3 WNT5A WNT6 WNT2B WNT5B LRP6

2.72e-0598856M39731
PathwayREACTOME_MET_ACTIVATES_PTK2_SIGNALING

LAMA1 LAMA3 LAMB2 MET

2.99e-0530854M27772
PathwayWP_WNT_SIGNALING_AND_PLURIPOTENCY

WNT3 WNT5A WNT6 WNT2B WNT5B LRP6

3.22e-05101856M39387
PathwayWP_WNT_SIGNALING_PATHWAY_AND_PLURIPOTENCY

WNT3 WNT5A WNT6 WNT2B WNT5B LRP6

3.22e-05101856MM15829
PathwayWP_WNT_SIGNALING

WNT3 WNT5A WNT6 WNT2B WNT5B

3.23e-0561855MM15893
PathwayPID_INTEGRIN4_PATHWAY

LAMA1 LAMA3 LAMB2

3.37e-0511853M158
PathwayREACTOME_ETHANOL_OXIDATION

ADH1A ADH1B ADH1C

3.37e-0511853MM15405
PathwayWP_BREAST_CANCER_PATHWAY

WNT3 WNT5A WNT6 WNT2B WNT5B LRP6 NOTCH2

3.92e-05154857M39739
PathwayREACTOME_ETHANOL_OXIDATION

ADH1A ADH1B ADH1C

4.48e-0512853M14663
PathwayWP_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_IN_COLORECTAL_CANCER

WNT3 WNT5A WNT6 WNT2B WNT5B LRP6 NOTCH2

5.20e-05161857M39770
PathwayWP_WNT_SIGNALING_WP428

WNT3 WNT5A WNT6 WNT2B WNT5B LRP6

6.07e-05113856M39669
PathwayWP_ESC_PLURIPOTENCY_PATHWAYS

WNT3 WNT5A WNT6 WNT2B WNT5B LRP6

7.02e-05116856MM15863
PathwayWP_EMBRYONIC_STEM_CELL_PLURIPOTENCY_PATHWAYS

WNT3 WNT5A WNT6 WNT2B WNT5B LRP6

7.37e-05117856M39530
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

VWF LAMA1 LAMA3 LAMB2 ITGB2 FBLN1 FURIN SCUBE3 LRP4

7.93e-05300859M610
PathwayREACTOME_INLB_MEDIATED_ENTRY_OF_LISTERIA_MONOCYTOGENES_INTO_HOST_CELL

STAM2 STAM MET

9.14e-0515853M27774
PathwayWP_FATTY_ACID_OMEGAOXIDATION

ADH1A ADH1B ADH1C

9.14e-0515853M39717
PathwayREACTOME_MET_PROMOTES_CELL_MOTILITY

LAMA1 LAMA3 LAMB2 MET

1.05e-0441854M27778
PathwayKEGG_PATHWAYS_IN_CANCER

WNT3 WNT5A WNT6 WNT2B LAMA1 LAMA3 LAMB2 WNT5B MET

1.46e-04325859M12868
PathwayWP_POLYCYSTIC_KIDNEY_DISEASE_PATHWAY

WNT3 WNT5A WNT6 WNT2B WNT5B

1.59e-0485855M48315
PathwayPID_A6B1_A6B4_INTEGRIN_PATHWAY

LAMA1 LAMA3 LAMB2 MET

1.66e-0446854M239
PathwayREACTOME_LISTERIA_MONOCYTOGENES_ENTRY_INTO_HOST_CELLS

STAM2 STAM MET

2.24e-0420853M27780
PathwayWP_CANCER_PATHWAYS

WNT3 WNT5A WNT6 WNT2B LAMA1 LAMA3 LAMB2 WNT5B MET LRP6 NOTCH2

2.25e-045078511M48302
PathwayREACTOME_NEGATIVE_REGULATION_OF_MET_ACTIVITY

STAM2 STAM MET

2.60e-0421853MM15347
PathwayREACTOME_NEGATIVE_REGULATION_OF_MET_ACTIVITY

STAM2 STAM MET

2.60e-0421853M27645
PathwayKEGG_WNT_SIGNALING_PATHWAY

WNT3 WNT5A WNT6 WNT2B WNT5B LRP6

2.98e-04151856M19428
PathwayKEGG_MELANOGENESIS

WNT3 WNT5A WNT6 WNT2B WNT5B

3.56e-04101855M7761
PathwayKEGG_MEDICUS_REFERENCE_DEUBIQUITINATION_OF_H2AK119

ASXL1 ASXL3 ASXL2

4.98e-0426853M47923
PathwayWP_DNA_DAMAGE_RESPONSE_ONLY_ATM_DEPENDENT

WNT3 WNT5A WNT6 WNT2B WNT5B

5.27e-04110855M39492
PathwayREACTOME_SIGNALING_BY_WNT

WNT3 WNT5A WNT6 PSMB1 WNT2B WNT5B LRP6

5.92e-04239857MM14756
PathwayPID_WNT_SIGNALING_PATHWAY

WNT3 WNT5A LRP6

6.22e-0428853M77
PathwayREACTOME_RA_BIOSYNTHESIS_PATHWAY

ADH1A ADH1B ADH1C

6.22e-0428853MM15188
PathwayWP_ALPHA_6_BETA_4_INTEGRIN_SIGNALING_PATHWAY

LAMA1 LAMA3 LAMB2 MET

6.68e-0466854MM15925
PathwayREACTOME_SIGNALING_BY_MET

STAM2 STAM MET MEGF6

7.07e-0467854MM15345
PathwayBIOCARTA_REELIN_PATHWAY

VLDLR LRP8

7.40e-047852MM1566
PathwayBIOCARTA_REELIN_PATHWAY

VLDLR LRP8

7.40e-047852M22049
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

SSPOP ADAMTS10 MUC5AC NOTCH2

7.47e-0468854M27303
PathwayREACTOME_LAMININ_INTERACTIONS

LAMA1 LAMA3 LAMB2

7.64e-0430853M27216
PathwayWP_ETHANOL_EFFECTS_ON_HISTONE_MODIFICATIONS

ADH1A ADH1B ADH1C

8.42e-0431853M39714
PathwayREACTOME_BACTERIAL_INFECTION_PATHWAYS

STAM2 STAM MET FURIN

8.80e-0471854M48033
PathwayWP_FOCAL_ADHESION

VWF LAMA1 LAMA3 LAMB2 ITGB2 MET

9.23e-04187856MM15913
PathwayREACTOME_SEMA4D_MEDIATED_INHIBITION_OF_CELL_ATTACHMENT_AND_MIGRATION

SEMA4D MET

9.83e-048852M27325
PathwayREACTOME_SEMA4D_MEDIATED_INHIBITION_OF_CELL_ATTACHMENT_AND_MIGRATION

SEMA4D MET

9.83e-048852MM15045
PathwayWP_ALZHEIMERS_DISEASE

WNT3 WNT5A WNT6 PSMB1 WNT2B WNT5B LRP6

9.94e-04261857M42565
PathwayWP_ALPHA_6_BETA_4_SIGNALING

LAMA1 LAMA3 LAMB2

1.01e-0333853M39503
PathwayREACTOME_ECM_PROTEOGLYCANS

LAMA1 LAMA3 LAMB2 LRP4

1.14e-0376854M27219
PathwayREACTOME_RNA_POLYMERASE_II_TRANSCRIPTION

PSMB1 ZNF300 ZNF233 ZNF302 ZNF529 ZNF710 ZNF707 ZNF250 MET KMT2C ZSCAN32 ZNF776 ZNF394 FURIN NR3C2 MNAT1 NOTCH2 ZNF222

1.34e-0313878518M734
PathwayKEGG_ECM_RECEPTOR_INTERACTION

VWF LAMA1 LAMA3 LAMB2

1.65e-0384854M7098
PathwayKEGG_TYROSINE_METABOLISM

ADH1A ADH1B ADH1C

2.05e-0342853M16743
PathwayKEGG_FATTY_ACID_METABOLISM

ADH1A ADH1B ADH1C

2.05e-0342853M699
PathwayWP_FOCAL_ADHESION_PI3KAKTMTORSIGNALING

VWF LAMA1 LAMA3 LAMB2 TEK ITGB2 MET

2.29e-03302857M39719
PathwayWP_RETINOL_METABOLISM

ADH1A ADH1B ADH1C

2.34e-0344853MM15851
PathwayREACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS

WNT3 WNT5A WNT6 WNT2B

2.49e-0394854M797
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00382

NFX1 NOTCH2

2.68e-0313852M47534
PathwayKEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_SOST_LRP4

LRP4 LRP6

3.12e-0314852M47834
PathwayREACTOME_SIGNALING_BY_RETINOIC_ACID

ADH1A ADH1B ADH1C

3.19e-0349853MM15186
PathwayREACTOME_CARGO_RECOGNITION_FOR_CLATHRIN_MEDIATED_ENDOCYTOSIS

STAM2 WNT5A STAM LRP2

3.34e-03102854MM15498
PathwayWP_FOCAL_ADHESION_PI3KAKTMTOR_SIGNALING_PATHWAY

VWF LAMA1 LAMA3 LAMB2 TEK ITGB2 MET

3.50e-03326857MM15917
PathwayWP_ALZHEIMERS_DISEASE_AND_MIRNA_EFFECTS

WNT3 WNT5A WNT6 PSMB1 WNT2B WNT5B LRP6

3.50e-03326857M39379
PathwayREACTOME_PHASE_I_FUNCTIONALIZATION_OF_COMPOUNDS

ADH1A ADH1B ADH1C FDX1

3.58e-03104854M738
PathwayREACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING

SEMA4D MET

3.59e-0315852MM15037
PathwayREACTOME_PENTOSE_PHOSPHATE_PATHWAY

PRPS2 PRPS1

3.59e-0315852M27682
PathwayREACTOME_NEGATIVE_REGULATION_OF_TCF_DEPENDENT_SIGNALING_BY_WNT_LIGAND_ANTAGONISTS

WNT5A LRP6

3.59e-0315852M27273
PathwayREACTOME_COBALAMIN_CBL_VITAMIN_B12_TRANSPORT_AND_METABOLISM

MMADHC LRP2

3.59e-0315852MM14762
PathwayREACTOME_PENTOSE_PHOSPHATE_PATHWAY

PRPS2 PRPS1

3.59e-0315852MM15404
PathwayREACTOME_CARGO_RECOGNITION_FOR_CLATHRIN_MEDIATED_ENDOCYTOSIS

STAM2 WNT5A STAM LRP2

3.71e-03105854M27752
PathwayREACTOME_PHASE_I_FUNCTIONALIZATION_OF_COMPOUNDS

ADH1A ADH1B ADH1C FDX1

3.71e-03105854MM14842
PathwayREACTOME_SIGNALING_BY_WNT

WNT3 WNT5A WNT6 PSMB1 WNT2B WNT5B LRP6

3.74e-03330857M7847
PathwayREACTOME_DISEASES_OF_METABOLISM

SSPOP MMADHC ADAMTS10 FDX1 MUC5AC NOTCH2

3.99e-03250856M27554
Pubmed

WNT5A is transported via lipoprotein particles in the cerebrospinal fluid to regulate hindbrain morphogenesis.

WNT3 WNT5A WNT6 WNT2B WNT5B LRP2 LRP4

2.24e-1135115730940800
Pubmed

Patterns of Wnt pathway activity in the mouse incisor indicate absence of Wnt/beta-catenin signaling in the epithelial stem cells.

WNT3 WNT5A WNT6 WNT2B WNT5B LRP4

5.97e-1121115619806668
Pubmed

Expression and estradiol regulation of Wnt genes in the mouse blastocyst identify a candidate pathway for embryo-maternal signaling at implantation.

WNT3 WNT5A WNT6 WNT2B WNT5B

1.06e-0915115515044261
Pubmed

Molecular genetic studies of Wnt signaling in the mouse.

WNT3 WNT5A WNT6 WNT2B WNT5B

1.54e-0916115510585256
Pubmed

c-Met and NF-κB-dependent overexpression of Wnt7a and -7b and Pax2 promotes cystogenesis in polycystic kidney disease.

WNT3 WNT5A WNT6 WNT2B MET

1.54e-0916115522677559
Pubmed

The Wnts.

WNT3 WNT5A WNT6 WNT2B WNT5B

1.54e-091611559889131
Pubmed

Wnt family proteins are secreted and associated with the cell surface.

WNT3 WNT5A WNT6 WNT2B WNT5B

2.17e-091711558167409
Pubmed

Canonical WNT signaling promotes mammary placode development and is essential for initiation of mammary gland morphogenesis.

WNT3 WNT5A WNT6 WNT2B WNT5B LRP6

2.45e-0937115615342465
Pubmed

Tissue-specific requirements of beta-catenin in external genitalia development.

WNT3 WNT5A WNT6 WNT2B WNT5B LRP6

2.90e-0938115618635608
Pubmed

Characterization of Wnt gene expression in developing and postnatal hair follicles and identification of Wnt5a as a target of Sonic hedgehog in hair follicle morphogenesis.

WNT3 WNT5A WNT6 WNT2B WNT5B

4.06e-0919115511520664
Pubmed

MESD is essential for apical localization of megalin/LRP2 in the visceral endoderm.

VLDLR LRP8 LRP2 LRP4 LRP6

7.06e-0921115521337463
Pubmed

The WNT7b promoter is regulated by TTF-1, GATA6, and Foxa2 in lung epithelium.

WNT3 WNT5A WNT6 WNT2B WNT5B

7.06e-0921115511914369
Pubmed

Epithelial Wnt10a Is Essential for Tooth Root Furcation Morphogenesis.

WNT3 WNT5A WNT6 WNT2B WNT5B

7.06e-0921115531914354
Pubmed

Characterization of Wnt signaling components and activation of the Wnt canonical pathway in the murine retina.

WNT3 WNT5A WNT6 WNT2B WNT5B

9.12e-0922115512815618
Pubmed

Members of the WNT signaling pathways are widely expressed in mouse ovaries, oocytes, and cleavage stage embryos.

WNT3 WNT5A WNT6 WNT2B WNT5B LRP6

1.10e-0847115618351675
Pubmed

Does murine spermatogenesis require WNT signalling? A lesson from Gpr177 conditional knockout mouse models.

WNT3 WNT5A WNT6 WNT2B WNT5B

1.16e-0823115527362799
Pubmed

A new nomenclature for int-1 and related genes: the Wnt gene family.

WNT3 WNT5A WNT6 WNT5B

1.41e-08911541846319
Pubmed

Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells.

WNT3 WNT5A WNT6 WNT2B WNT5B LRP6

1.43e-0849115619562671
Pubmed

Mouse Wnt genes exhibit discrete domains of expression in the early embryonic CNS and limb buds.

WNT3 WNT5A WNT6 WNT5B

2.35e-081011548275860
Pubmed

Expression patterns of Wnt genes during development of an anterior part of the chicken eye.

WNT5A WNT6 WNT2B WNT5B

2.35e-0810115416258938
Pubmed

The evolutionarily conserved porcupine gene family is involved in the processing of the Wnt family.

WNT3 WNT5A WNT6 WNT5B

2.35e-0810115410866835
Pubmed

Activation of the Wnt-beta catenin pathway in a cell population on the surface of the forebrain is essential for the establishment of olfactory axon connections.

WNT3 WNT5A WNT6 WNT2B WNT5B

2.76e-0827115517804636
Pubmed

Frizzled 1 and frizzled 2 genes function in palate, ventricular septum and neural tube closure: general implications for tissue fusion processes.

WNT3 WNT5A WNT6 WNT2B WNT5B

3.35e-0828115520940229
Pubmed

Ectodermal Wnt signaling regulates abdominal myogenesis during ventral body wall development.

WNT3 WNT5A WNT6 WNT2B WNT5B

3.35e-0828115524394376
Pubmed

Retinol/ethanol drug interaction during acute alcohol intoxication in mice involves inhibition of retinol metabolism to retinoic acid by alcohol dehydrogenase.

ADH1A ADH1B ADH1C

3.52e-083115311960985
Pubmed

Tissue-specific genetic variation in the level of mouse alcohol dehydrogenase is controlled transcriptionally in kidney and posttranscriptionally in liver.

ADH1A ADH1B ADH1C

3.52e-08311532474823
Pubmed

Chromosomal assignment of the alcohol dehydrogenase cluster locus to human chromosome 4q21-23 by in situ hybridization.

ADH1A ADH1B ADH1C

3.52e-08311532737681
Pubmed

Regulation of human class I alcohol dehydrogenases by bile acids.

ADH1A ADH1B ADH1C

3.52e-083115323772048
Pubmed

A negative regulatory element upstream from the mouse Adh-1 gene can down-regulate a heterologous promoter.

ADH1A ADH1B ADH1C

3.52e-08311538163197
Pubmed

ALDH expression characterizes G1-phase proliferating beta cells during pregnancy.

ADH1A ADH1B ADH1C

3.52e-083115324787690
Pubmed

Androgen induction of alcohol dehydrogenase in mouse kidney. Studies with a cDNA probe confirmed by nucleotide sequence analysis.

ADH1A ADH1B ADH1C

3.52e-08311533011597
Pubmed

Alcohol dehydrogenase isozymes in the mouse: genetic regulation, allelic variation among inbred strains and sex differences of liver and kidney A2 isozyme activity.

ADH1A ADH1B ADH1C

3.52e-08311536756216
Pubmed

Alcohol dehydrogenase 1 is a tubular mitophagy-dependent apoptosis inhibitor against septic acute kidney injury.

ADH1A ADH1B ADH1C

3.52e-083115337806378
Pubmed

Structure and function of a long alternating purine-pyrimidine sequence in the mouse alcohol dehydrogenase Adh-1 gene.

ADH1A ADH1B ADH1C

3.52e-08311537840644
Pubmed

Alcoholic fatty liver: its pathogenesis and mechanism of progression to inflammation and fibrosis.

ADH1A ADH1B ADH1C

3.52e-083115315670660
Pubmed

Stage and tissue-specific expression of the alcohol dehydrogenase 1 (Adh-1) gene during mouse development.

ADH1A ADH1B ADH1C

3.52e-08311538018987
Pubmed

Paracardial fat remodeling affects systemic metabolism through alcohol dehydrogenase 1.

ADH1A ADH1B ADH1C

3.52e-083115333586683
Pubmed

Cloning and sequencing of cDNA encoding the complete mouse liver alcohol dehydrogenase.

ADH1A ADH1B ADH1C

3.52e-08311533157987
Pubmed

Promoters for the human alcohol dehydrogenase genes ADH1, ADH2, and ADH3: interaction of CCAAT/enhancer-binding protein with elements flanking the ADH2 TATA box.

ADH1A ADH1B ADH1C

3.52e-08311532169444
Pubmed

A novel negative element in the promoter of the mouse alcohol dehydrogenase gene Adh-1.

ADH1A ADH1B ADH1C

3.52e-08311538486690
Pubmed

Individual susceptibility and alcohol effects:biochemical and genetic aspects.

ADH1A ADH1B ADH1C

3.52e-083115316801720
Pubmed

Recommended nomenclature for the vertebrate alcohol dehydrogenase gene family.

ADH1A ADH1B ADH1C

3.52e-083115310424757
Pubmed

The human class I alcohol dehydrogenase gene cluster: three genes are tandemly organized in an 80-kb-long segment of the genome.

ADH1A ADH1B ADH1C

3.52e-08311532347582
Pubmed

Beneficial effect of low ethanol intake on the cardiovascular system: possible biochemical mechanisms.

ADH1A ADH1B ADH1C

3.52e-083115317326332
Pubmed

Characterization of Asxl1, a murine homolog of Additional sex combs, and analysis of the Asx-like gene family.

ASXL1 ASXL3 ASXL2

3.52e-083115316412590
Pubmed

The role of alcohol dehydrogenase in retinoic acid homeostasis and fetal alcohol syndrome.

ADH1A ADH1B ADH1C

3.52e-08311537748347
Pubmed

Genetics of human alcohol and aldehyde dehydrogenases.

ADH1A ADH1B ADH1C

3.52e-08311533006456
Pubmed

Short-term selective breeding as a tool for QTL mapping: ethanol preference drinking in mice.

ADH1A ADH1B ADH1C

3.52e-08311539145544
Pubmed

Structure of the mouse Adh-1 gene and identification of a deletion in a long alternating purine-pyrimidine sequence in the first intron of strains expressing low alcohol dehydrogenase activity.

ADH1A ADH1B ADH1C

3.52e-08311533428612
Pubmed

Genetic and developmental regulation of mouse liver alcohol dehydrogenase.

ADH1A ADH1B ADH1C

3.52e-08311536816803
Pubmed

Functional proteomics of the epigenetic regulators ASXL1, ASXL2 and ASXL3: a convergence of proteomics and epigenetics for translational medicine.

ASXL1 ASXL3 ASXL2

3.52e-083115325835095
Pubmed

Ten kilobases of 5'-flanking region confers proper regulation of the mouse alcohol dehydrogenase-1 (Adh-1) gene in kidney and adrenal of transgenic mice.

ADH1A ADH1B ADH1C

3.52e-08311538973327
Pubmed

The discovery of the microsomal ethanol oxidizing system and its physiologic and pathologic role.

ADH1A ADH1B ADH1C

3.52e-083115315554233
Pubmed

ADH1C inhibits progression of colorectal cancer through the ADH1C/PHGDH /PSAT1/serine metabolic pathway.

ADH1A ADH1B ADH1C

3.52e-083115335354963
Pubmed

Purification and characterization of mouse alcohol dehydrogenase from two inbred strains that differ in total liver enzyme activity.

ADH1A ADH1B ADH1C

3.52e-08311536370228
Pubmed

Understanding the phenotypic spectrum of ASXL-related disease: Ten cases and a review of the literature.

ASXL1 ASXL3 ASXL2

3.52e-083115333751773
Pubmed

Three human alcohol dehydrogenase subunits: cDNA structure and molecular and evolutionary divergence.

ADH1A ADH1B ADH1C

3.52e-08311532935875
Pubmed

Wnt5a potentiates TGF-β signaling to promote colonic crypt regeneration after tissue injury.

WNT3 WNT5A WNT6 WNT2B WNT5B

4.04e-0829115522956684
Pubmed

3D representation of Wnt and Frizzled gene expression patterns in the mouse embryo at embryonic day 11.5 (Ts19).

WNT3 WNT5A WNT6 WNT2B WNT5B

4.04e-0829115518364260
Pubmed

Genetic interactions of the androgen and Wnt/beta-catenin pathways for the masculinization of external genitalia.

WNT3 WNT5A WNT6 WNT2B WNT5B

4.83e-0830115519282366
Pubmed

Atlas of Wnt and R-spondin gene expression in the developing male mouse lower urogenital tract.

WNT3 WNT5A WNT6 WNT2B WNT5B

4.83e-0830115521936019
Pubmed

Expression of all Wnt genes and their secreted antagonists during mouse blastocyst and postimplantation development.

WNT3 WNT5A WNT6 WNT2B WNT5B

4.83e-0830115515880404
Pubmed

Overactive Wnt5a signaling disrupts hair follicle polarity during mouse skin development.

WNT3 WNT5A WNT6 WNT2B WNT5B

4.83e-0830115536305473
Pubmed

Gene trap screening as an effective approach for identification of Wnt-responsive genes in the mouse embryo.

WNT3 WNT6 WNT2B WNT5B

5.50e-0812115415778975
Pubmed

Foxf2 in intestinal fibroblasts reduces numbers of Lgr5(+) stem cells and adenoma formation by inhibiting Wnt signaling.

WNT3 WNT5A WNT6 WNT2B WNT5B

1.09e-0735115523376422
Pubmed

Comprehensive expression analysis of all Wnt genes and their major secreted antagonists during mouse limb development and cartilage differentiation.

WNT3 WNT5A WNT6 WNT2B WNT5B

1.09e-0735115519185060
Pubmed

Dual regulation of planar polarization by secreted Wnts and Vangl2 in the developing mouse cochlea.

WNT3 WNT5A WNT6 WNT2B WNT5B

1.09e-0735115532907846
Pubmed

Stage-specific association of apolipoprotein A-I and E in developing mouse retina.

VLDLR LRP8 LRP2 LRP6

1.11e-0714115417389516
Pubmed

Wnt/Rspondin/β-catenin signals control axonal sorting and lineage progression in Schwann cell development.

WNT3 WNT5A WNT6 WNT2B WNT5B

1.26e-0736115524151333
Pubmed

Genetic regulation of gene-specific mRNA by ethanol in vivo and its possible role in ethanol preference in a cross with RI lines in mice.

ADH1A ADH1B ADH1C

1.41e-07411538813054
Pubmed

Distribution of class I, III and IV alcohol dehydrogenase mRNAs in the adult rat, mouse and human brain.

ADH1A ADH1B ADH1C

1.41e-074115312631290
Pubmed

Molecular analysis of mouse alcohol dehydrogenase: nucleotide sequence of the Adh-1 gene and genetic mapping of a related nucleotide sequence to chromosome 3.

ADH1A ADH1B ADH1C

1.41e-07411532893758
Pubmed

Oncogenic Truncations of ASXL1 Enhance a Motif for BRD4 ET-Domain Binding.

ASXL1 ASXL3 ASXL2

1.41e-074115334536441
Pubmed

Overexpression of alcohol dehydrogenase exacerbates ethanol-induced contractile defect in cardiac myocytes.

ADH1A ADH1B ADH1C

1.41e-074115311893554
Pubmed

Metabolic pharmacokinetics of early chronic alcohol consumption mediated by liver alcohol dehydrogenases 1 and 3 in mice.

ADH1A ADH1B ADH1C

1.41e-074115329663519
Pubmed

Genetic evidence that retinaldehyde dehydrogenase Raldh1 (Aldh1a1) functions downstream of alcohol dehydrogenase Adh1 in metabolism of retinol to retinoic acid.

ADH1A ADH1B ADH1C

1.41e-074115312851412
Pubmed

ADH1 and ADH4 alcohol/retinol dehydrogenases in the developing adrenal blastema provide evidence for embryonic retinoid endocrine function.

ADH1A ADH1B ADH1C

1.41e-07411539733106
Pubmed

Hepatic CYP2B10 is highly induced by binge ethanol and contributes to acute-on-chronic alcohol-induced liver injury.

ADH1A ADH1B ADH1C

1.41e-074115336224745
Pubmed

Retinoic acid and alcohol/retinol dehydrogenase in the mouse adrenal gland: a potential endocrine source of retinoic acid during development.

ADH1A ADH1B ADH1C

1.41e-07411539202249
Pubmed

Effects of polymorphisms in untranslated regions of the class I alcohol dehydrogenase (ADH) genes on alcohol metabolism in Japanese subjects and transcriptional activity in HepG2 cells.

ADH1A ADH1B ADH1C

1.41e-074115319618839
Pubmed

Mouse mitochondrial aldehyde dehydrogenase isozymes: purification and molecular properties.

ADH1A ADH1B ADH1C

1.41e-07411533996732
Pubmed

Genetic mapping of a possible new alcohol dehydrogenase sequence to mouse chromosome 3 at the Adh-1/Adh-3 complex.

ADH1A ADH1B ADH1C

1.41e-07411539241435
Pubmed

Families of retinoid dehydrogenases regulating vitamin A function: production of visual pigment and retinoic acid.

ADH1A ADH1B ADH1C

1.41e-074115310880953
Pubmed

Localization of class I and class IV alcohol dehydrogenases in mouse testis and epididymis: potential retinol dehydrogenases for endogenous retinoic acid synthesis.

ADH1A ADH1B ADH1C

1.41e-07411539002638
Pubmed

Opposing actions of cellular retinol-binding protein and alcohol dehydrogenase control the balance between retinol storage and degradation.

ADH1A ADH1B ADH1C

1.41e-074115315193143
Pubmed

Regulated expression of Wnt family members during neuroectodermal differentiation of P19 embryonal carcinoma cells: overexpression of Wnt-1 perturbs normal differentiation-specific properties.

WNT3 WNT5A WNT6

1.41e-07411537958454
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

SPIRE2 PHF12 UBR4 NSD1 LAMB2 KMT2C THADA HEG1 WIZ MROH1 MEGF6 FURIN ZNF516 NFX1 LRP4 HERC2 NOTCH2

1.42e-0711051151735748872
Pubmed

Integrated analysis of Wnt signalling system component gene expression.

WNT3 WNT5A WNT6 WNT2B WNT5B

1.45e-0737115535831952
Pubmed

Patterns of Wnt/Fzd/LRP gene expression during embryonic hematopoiesis.

WNT3 WNT5A WNT6 WNT5B LRP6

1.45e-0737115518800919
Pubmed

Expression patterns of Wnt genes in mouse gut development.

WNT3 WNT5A WNT6 WNT5B

1.51e-0715115411429295
Pubmed

Wnt11 promotes cardiomyocyte development by caspase-mediated suppression of canonical Wnt signals.

WNT3 WNT5A WNT6 WNT2B WNT5B

1.67e-0738115521041481
Pubmed

Epidermal Wnt controls hair follicle induction by orchestrating dynamic signaling crosstalk between the epidermis and dermis.

WNT3 WNT5A WNT6 WNT2B WNT5B

1.67e-0738115523190887
Pubmed

Distinct requirements for cranial ectoderm and mesenchyme-derived wnts in specification and differentiation of osteoblast and dermal progenitors.

WNT3 WNT5A WNT6 WNT2B WNT5B

1.91e-0739115524586192
Pubmed

Wnt signaling in the murine diastema.

WNT5A WNT6 LRP4 LRP6

2.61e-0717115421531785
Pubmed

Cooperative and independent functions of FGF and Wnt signaling during early inner ear development.

WNT3 WNT5A WNT6 WNT5B

2.61e-0717115426443994
Pubmed

Restriction of Wnt signaling in the dorsal otocyst determines semicircular canal formation in the mouse embryo.

WNT3 WNT5A WNT6 WNT2B

3.35e-0718115422166339
Pubmed

Linkage of phosphoribosylpyrophosphate synthetases 1 and 2, Prps1 and Prps2, on the mouse X chromosome.

PRPS2 PLP1 PRPS1

3.50e-07511537849396
Pubmed

Distinct retinoid metabolic functions for alcohol dehydrogenase genes Adh1 and Adh4 in protection against vitamin A toxicity or deficiency revealed in double null mutant mice.

ADH1A ADH1B ADH1C

3.50e-075115311836246
Pubmed

Retinoic acid synthesis in mouse embryos during gastrulation and craniofacial development linked to class IV alcohol dehydrogenase gene expression.

ADH1A ADH1B ADH1C

3.50e-07511538621625
Pubmed

Assignment of the rat genes coding for alpha 1-antitrypsin (PI), phosphoenolpyruvate carboxykinase (PEPCK), alcohol dehydrogenase (ADH), and fructose-1,6-bisphosphatase (FDP).

ADH1A ADH1B ADH1C

3.50e-07511531316195
InteractionIGFL3 interactions

VLDLR WNT5A LAMA1 LAMA3 LAMB2 FBLN1 LRP2 LRP4 NOTCH2

2.87e-10751109int:IGFL3
InteractionPORCN interactions

WNT3 WNT5A WNT6 WNT5B

1.45e-06161104int:PORCN
InteractionDEFB125 interactions

UBR4 LAMA3 FBLN1 LRP2

3.81e-06201104int:DEFB125
InteractionHBG1 interactions

ASXL1 TRIM54 ASXL3 ASXL2

4.68e-06211104int:HBG1
InteractionNTRK3 interactions

STAM2 TRIP6 DSG2 NSD1 NEU3 STAM MET DNAJC10 NFXL1 NOTCH2 ZC3HAV1

6.41e-0637411011int:NTRK3
InteractionSLURP1 interactions

LAMA3 LAMB2 MET FBLN1 ASXL2 NOTCH2 PRPS1

1.42e-051441107int:SLURP1
InteractionEPHA7 interactions

PRPS2 STAM2 DSG2 WNT5A UBR4 PSMB1 LAMB2 HERC2 NOTCH2

2.45e-052821109int:EPHA7
InteractionLTBP4 interactions

ZNF707 FBLN1 DNAJC10 MZF1 NOTCH2

3.26e-05671105int:LTBP4
InteractionSOST interactions

LRP2 LRP4 LRP6 HERC2

3.86e-05351104int:SOST
InteractionCAV1 interactions

PRPS2 STAM2 DSG2 NEU3 STAM TEK LRP8 MET SPRY4 LRP6 NR3C2 NOTCH2 ZC3HAV1 PRPS1

3.98e-0572411014int:CAV1
InteractionADH1B interactions

ADH1A ADH1B ADH1C

4.35e-05131103int:ADH1B
InteractionLYPD6B interactions

UBR4 LAMB2 FBLN1 PRPS1

5.96e-05391104int:LYPD6B
InteractionHPRT1 interactions

ASXL1 PPAT TEK MET ASXL3 ASXL2

6.39e-051251106int:HPRT1
InteractionPSMC3IP interactions

ASXL1 ASXL3 ASXL2 NOTCH2

7.28e-05411104int:PSMC3IP
InteractionATN1 interactions

TRIP6 SSPOP KMT2C FBLN1 MEGF6 LRP2 MEGF11

7.53e-051871107int:ATN1
InteractionNOTCH2 interactions

USP53 DTX3 WNT5A PSMB1 LAMB2 ZNF407 ZNF518A ZNF707 FBLN1 NOTCH2

1.08e-0442311010int:NOTCH2
InteractionTOP3B interactions

SPIRE2 PHF12 UBR4 NSD1 LAMB2 ZNF250 KMT2C THADA HEG1 WIZ MROH1 MEGF6 FURIN ZNF516 NFX1 LRP4 ZFR HERC2 NOTCH2 ZC3HAV1

1.24e-04147011020int:TOP3B
InteractionAPBA2 interactions

ZNF518A LRP8 LRP2 HERC2

1.36e-04481104int:APBA2
InteractionZNF383 interactions

LRP4 LRP6 ZNF572

1.44e-04191103int:ZNF383
Cytoband4q23

ADH1A ADH1B ADH1C

1.69e-052011534q23
CytobandEnsembl 112 genes in cytogenetic band chr4q23

ADH1A ADH1B ADH1C

1.12e-04371153chr4q23
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF300 ZNF407 ZNF233 ZNF302 ZNF883 ZNF529 ZNF518A ZNF710 ZNF707 ZNF250 ZSCAN32 ZNF776 ZNF394 WIZ MZF1 ZNF516 PRDM14 ZNF222 ZNF572

1.05e-09718871928
GeneFamilyLow density lipoprotein receptors

VLDLR LRP8 LRP2 LRP4 LRP6

2.87e-0913875634
GeneFamilyWnt family|Endogenous ligands

WNT3 WNT5A WNT6 WNT2B WNT5B

2.53e-0819875360
GeneFamilyPHD finger proteins

PHF12 NSD1 AIRE BPTF KMT2C NFX1

4.70e-069087688
GeneFamilyAlcohol dehydrogenases

ADH1A ADH1B ADH1C

5.92e-068873397
GeneFamilyLaminin subunits

LAMA1 LAMA3 LAMB2

2.29e-0512873626
GeneFamilyRing finger proteins

TRIM51 DTX3 TRIM54 RNF17 TRIM50 LONRF3 MNAT1 RNF212B

5.35e-0527587858
GeneFamilyESCRT-0

STAM2 STAM

6.85e-0538721115
GeneFamilyRing finger proteins|Tripartite motif containing|ARF GTPase family

TRIM51 TRIM54 TRIM50 TRIM51G

1.14e-039587459
CoexpressionNABA_MATRISOME

SEMA4D VWF WNT3 WNT5A WNT6 WNT2B LAMA1 LAMA3 LAMB2 ADAM29 SSPOP SVEP1 ADAMTS10 WNT5B FBLN1 MEGF6 CLEC4G SCUBE3 EGFLAM MUC5AC MEGF11

2.26e-09100811421MM17056
CoexpressionNABA_MATRISOME

SEMA4D VWF WNT3 WNT5A WNT6 WNT2B LAMA1 LAMA3 LAMB2 ADAM29 SSPOP SVEP1 ADAMTS10 WNT5B FBLN1 MEGF6 CLEC4G SCUBE3 EGFLAM MUC5AC MEGF11

3.09e-09102611421M5889
CoexpressionNABA_ECM_GLYCOPROTEINS

VWF LAMA1 LAMA3 LAMB2 SSPOP SVEP1 FBLN1 EGFLAM

1.95e-061911148MM17059
CoexpressionNABA_ECM_GLYCOPROTEINS

VWF LAMA1 LAMA3 LAMB2 SSPOP SVEP1 FBLN1 EGFLAM

2.37e-061961148M3008
CoexpressionPASINI_SUZ12_TARGETS_UP

LAMA1 AIRE RNF17 KMT2C PRDM14 ZC3HAV1

1.03e-051131146M2291
CoexpressionPASINI_SUZ12_TARGETS_UP

LAMA1 AIRE RNF17 KMT2C PRDM14 ZC3HAV1

1.83e-051251146MM1065
CoexpressionNABA_MATRISOME_ASSOCIATED

SEMA4D WNT3 WNT5A WNT6 WNT2B ADAM29 ADAMTS10 WNT5B MEGF6 CLEC4G SCUBE3 MUC5AC MEGF11

2.00e-0573811413MM17058
CoexpressionNABA_MATRISOME_ASSOCIATED

SEMA4D WNT3 WNT5A WNT6 WNT2B ADAM29 ADAMTS10 WNT5B MEGF6 CLEC4G SCUBE3 MUC5AC MEGF11

2.40e-0575111413M5885
CoexpressionNABA_CORE_MATRISOME

VWF LAMA1 LAMA3 LAMB2 SSPOP SVEP1 FBLN1 EGFLAM

2.45e-052701148MM17057
CoexpressionNABA_CORE_MATRISOME

VWF LAMA1 LAMA3 LAMB2 SSPOP SVEP1 FBLN1 EGFLAM

2.79e-052751148M5884
CoexpressionSMID_BREAST_CANCER_LUMINAL_A_UP

ENPP2 SVEP1 ADH1B FBLN1 DHRS2

3.54e-05851145M7517
CoexpressionDELYS_THYROID_CANCER_DN

ZNF302 TEK SSPOP ADH1A ADH1B FBLN1 LRP2

7.36e-052331147M13273
CoexpressionVART_KSHV_INFECTION_ANGIOGENIC_MARKERS_UP

WNT5A WNT2B TEK WNT5B HEG1 NOTCH2

8.08e-051631146M12112
CoexpressionNABA_SECRETED_FACTORS

WNT3 WNT5A WNT6 WNT2B WNT5B MEGF6 SCUBE3 MEGF11

1.18e-043381148MM17064
CoexpressionNABA_SECRETED_FACTORS

WNT3 WNT5A WNT6 WNT2B WNT5B MEGF6 SCUBE3 MEGF11

1.31e-043431148M5883
CoexpressionHEBERT_MATRISOME_TNBC_LUNG_METASTASIS

LAMA1 LAMA3 LAMB2

1.33e-04231143M48001
CoexpressionBOQUEST_STEM_CELL_UP

WNT5A SVEP1 ADH1B ADH1C FBLN1 PLP1 NOTCH2

1.49e-042611147M1834
CoexpressionAtlaskidney_P4_CapMesRenVes_Crym_k-means-cluster#2_top-relative-expression-ranked_500

PRPS2 SEMA4D VLDLR ENPP2 MET LRP2

3.44e-06791106gudmap_kidney_P4_CapMesRenVes_Crym_k2_500
CoexpressionAtlaskidney_e15.5_Podocyte_MafB_k-means-cluster#4_top-relative-expression-ranked_200

VLDLR ENPP2 MET SLC12A1 LRP2

2.20e-05651105gudmap_kidney_e15.5_Podocyte_MafB_k4_200
CoexpressionAtlaskidney_P4_CapMesRenVes_Crym_top-relative-expression-ranked_500

PRPS2 SEMA4D VLDLR ENPP2 LAMA1 MET SCUBE3 LRP2 LRP4 NOTCH2

4.24e-0539811010gudmap_kidney_P4_CapMesRenVes_Crym_500
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

WNT2B SVEP1 ADH1B FBLN1 MEGF6 EGFLAM NOTCH2

3.53e-0717411579c916af5eebd932f67dc9117e1d26ff194a2ff2c
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

WNT2B SVEP1 ADH1B FBLN1 MEGF6 EGFLAM NOTCH2

3.53e-071741157bc71521f44a5fe013af42b06b5d1bd2446ecf3b5
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VLDLR NSD1 ADAMTS10 FBLN1 HEG1 ZFR NR3C2

3.82e-071761157749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCellfacs-MAT-Fat-3m|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WNT5A WNT2B LAMB2 FBLN1 LRP6 EGFLAM PLP1

5.95e-0718811577da9750255efbc5cf9aed7e3105a337fac63b9f0
ToppCelldroplet-Heart-4Chambers-21m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4D VWF DSG2 TEK ADH1A MEGF6 CLEC4G

7.35e-071941157c5e77650d7abee339ec38fa78a622bb124db3fa5
ToppCelldroplet-Heart-4Chambers-21m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4D VWF DSG2 TEK ADH1A MEGF6 CLEC4G

7.61e-071951157df644b4c3ddccd34614ece5a2378000e6bc0fa10
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell_prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

VWF ENPP2 WNT2B LAMA3 TEK WNT5B

3.02e-061541156e51a5114f0ec38f997f5b8bbf3a7770f98595474
ToppCellfrontal_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Osr1_Mc5r|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

WNT6 LAMA1 SVEP1 FBLN1 EGFLAM NOTCH2

4.98e-0616811569930bd63b60c03f0152838a79eef77da1c2dd8e5
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

VLDLR SVEP1 ADH1A ADAMTS10 ZNF250 EGFLAM

5.15e-06169115616c52a0f6d96ecc1832922fce9b39691849f0d73
ToppCelldroplet-Lung-nan-3m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENPP2 DTX3 SSPOP SPRY4 LRP4 EGFLAM

6.72e-06177115665709bd546cb1ec6aa2ddd8b2adb46e174eb9a9a
ToppCelldroplet-Lung-nan-3m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENPP2 DTX3 SSPOP SPRY4 LRP4 EGFLAM

6.72e-0617711568684d47a547e2a06496f15e8da0200ecddc431e0
ToppCell3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

USP53 SVEP1 ADH1B FBLN1 LRP4 PLP1

6.94e-06178115609475e522dc1b8cf9ff1c25de5d1e3082b162948
ToppCell3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

USP53 SVEP1 ADH1B FBLN1 LRP4 PLP1

6.94e-06178115635de8f791b0e78a6caf52ff095f05e204a59e828
ToppCell3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

USP53 SVEP1 ADH1B FBLN1 LRP4 PLP1

6.94e-061781156000d25f3f13cc76cf39c46c312c6fafc2ea4f368
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

WNT5A ADAMTS10 MET FBLN1 MEGF6 LRP4

8.13e-0618311567eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCellfacs-Heart-LA-24m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWF DSG2 TEK ADH1A HEG1 MEGF6

9.19e-061871156d9943e65eedab73d141eae524e2411653a751705
ToppCellfacs-Heart-LA-24m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWF DSG2 TEK ADH1A HEG1 MEGF6

9.19e-0618711567b13c3b67d66f3afb410141d5471c9e78a4d8623
ToppCellE16.5-samps-Mesenchymal|E16.5-samps / Age Group, Lineage, Cell class and subclass

VLDLR WNT5A SVEP1 ADH1A LRP4 EGFLAM

9.48e-0618811563f0f662be684e3a4c6652e636cc135a39a1d2790
ToppCelldroplet-Heart-nan-3m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4D VWF DSG2 TEK HEG1 MEGF6

9.77e-0618911568e583ec4df0f5b79ce5211cc99ecd8616d180bde
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

VWF ENPP2 LAMA3 TEK WNT5B HEG1

9.77e-0618911566463890d8dbee4bc198f91628a5f784970de786a
ToppCelldroplet-Heart-nan-24m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWF DSG2 TEK ADH1A MEGF6 CLEC4G

9.77e-0618911561137583e21d874c201c20581ba1995e2bfa3de59
ToppCellE18.5-samps-Mesenchymal|E18.5-samps / Age Group, Lineage, Cell class and subclass

WNT5A SVEP1 ADH1A FBLN1 LRP4 NOTCH2

9.77e-0618911560c18d3de4720759cf802eefb4d0ddde2a9246a1a
ToppCelldroplet-Heart-nan-3m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4D VWF DSG2 TEK HEG1 MEGF6

9.77e-061891156fb2253b8463d08b3d28e952a31a23dea2c2d986b
ToppCelldroplet-Heart-nan-24m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWF DSG2 TEK ADH1A MEGF6 CLEC4G

1.01e-0519011567068754c29f63a331e2b6c54715f3b26f37ad32b
ToppCelldroplet-Heart-4Chambers-18m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4D VWF DSG2 TEK ADH1A MEGF6

1.01e-0519011566f71a9f74af7cd9a674753cfc9833ebe5bba0fa2
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

VWF ENPP2 LAMA3 TEK WNT5B HEG1

1.07e-0519211563259cb89d6bcf0a3c6ff1f64d85e8a1f54124e91
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

VWF ENPP2 WNT2B LAMA3 TEK HEG1

1.07e-05192115656b021c297a21dff357531f21e2464f85186106d
ToppCellfacs-MAT-Fat-3m-Mesenchymal-mesenchymal_stem_cell_of_adipose|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WNT5A LAMB2 SVEP1 ADH1A FBLN1 EGFLAM

1.10e-051931156f95b95c58a6edb8a03dd15ae166f47f9f33d8bd6
ToppCellfacs-MAT-Fat-3m-Mesenchymal-mesenchymal_progenitor|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WNT5A LAMB2 SVEP1 ADH1A FBLN1 EGFLAM

1.10e-05193115685faf6c5ce4769615a4eca036e2ba307e176bb52
ToppCellfacs-MAT-Fat-3m-Mesenchymal|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WNT5A LAMB2 SVEP1 ADH1A FBLN1 EGFLAM

1.10e-051931156110a7d2ba7d066c2be38be98b643b76c520dd980
ToppCellPND01-03-samps-Mesenchymal|PND01-03-samps / Age Group, Lineage, Cell class and subclass

WNT5A SVEP1 ADH1A LRP4 EGFLAM NOTCH2

1.13e-0519411564f9bd0ded0dde1df885850714f29e73e992539a5
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

VWF ENPP2 WNT2B LAMA3 TEK HEG1

1.17e-0519511566bdef651cf73d7381e5012d0eb3c809138fb6b92
ToppCellNS-critical-LOC-Epithelial-Secretory|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DSG2 LAMB2 ADH1B MET FBLN1 MUC5AC

1.17e-051951156b0d782eeee30c797b4da9b3be29b864983fd9e71
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

VWF ENPP2 LAMA3 TEK WNT5B HEG1

1.17e-051951156d35102f95bb1e419d2df05ff0a01b6c5c923acef
ToppCellE17.5-Mesenchymal|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

VLDLR WNT5A SVEP1 ADH1C FBLN1 EGFLAM

1.20e-051961156b4ee991445b612506372b9361ebfe72cb59b811e
ToppCelldroplet-Heart-nan-18m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4D VWF DSG2 TEK ADH1A MEGF6

1.20e-051961156e386526332138e636aef2542c11316347a45689c
ToppCellNon-neuronal-Non-dividing-Radial_Glia-tRG|World / Primary Cells by Cluster

TRIP6 LAMA1 LAMB2 HEG1 LRP4 NOTCH2

1.24e-05197115661749ccafeb938c310cff1de5ff924a1c794325a
ToppCellNon-neuronal-Non-dividing-Radial_Glia-tRG-25|World / Primary Cells by Cluster

TRIP6 LAMA1 LAMB2 HEG1 LRP4 NOTCH2

1.24e-0519711569d4ffa3680f92c91d0a081f9a8ec5ebfec6bdcf6
ToppCellNS-critical-d_16-33-Epithelial-Secretory|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DSG2 LAMB2 ADH1B MET FBLN1 MUC5AC

1.24e-051971156a72047b7428c0d4aaf016c1ac23dc30919260fd8
ToppCellE18.5-Mesenchymal|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ENPP2 WNT5A SVEP1 ADH1A FBLN1 EGFLAM

1.27e-051981156a16aa41eab2e297e56de43c22c355df0f79315da
ToppCell10x3'2.3-week_17-19-Mesenchymal_fibro-stroma-arteriolar_fibroblast|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

LAMB2 SVEP1 ADH1B ADH1C FBLN1 PLP1

1.31e-05199115695d95e9b7bd3933188998ae94986213eb0f1e5ea
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

VWF ENPP2 TEK BPTF KMT2C HEG1

1.35e-052001156dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellTracheal-10x3prime_v2-Stromal-Peri/Epineurial_|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

USP53 WNT6 ZNF407 ADH1B SRRD EGFLAM

1.35e-052001156f7c3a8f5ac156c05ad7335d6d142c154c7d86449
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-3|TCGA-Brain / Sample_Type by Project: Shred V9

UBR4 HEATR5A ZNF518A ZNF250 ASXL3

4.26e-051491155768877bade04ca0321593b8470b5011ad8270431
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TRIP6 UBR4 ADAMTS10 LONRF3 TMEM181

5.30e-051561155895927228c93cd090303984c5be6ebfb59ed6f3a
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWF WNT5A LAMB2 TEK LRP8

5.64e-051581155ba9998cbf786c515d30fe42de02c7a246db1b6f9
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWF WNT5A LAMB2 TEK LRP8

5.64e-051581155a2efcc184ef13d81373e3690253ba35f6be09c5f
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWF WNT5A LAMB2 TEK LRP8

5.64e-051581155e52eff2bd1e7e0ce9c278ed5109802865e0fe69c
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW09-Macroglial|GW09 / Sample Type, Dataset, Time_group, and Cell type.

LAMA1 WNT5B PLP1 NOTCH2

6.37e-058311547893ce9fbf34c6250dca9c265fe9b2d4cb889ade
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

VWF WNT2B TEK RNF17 HEG1

6.92e-051651155a74751e0ec857aa974bec04ccc747c004a8f6e01
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADAMTS10 MET P2RY11 NFXL1 MUC5AC

7.12e-05166115560060b03f2abfa3cc08107ab5a9f578e60e4ae16
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADAMTS10 MET P2RY11 NFXL1 MUC5AC

7.12e-051661155ec9161d388db5a257b8d125c14f9dd911d5d5d4a
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell_prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

VWF ENPP2 LAMA3 TEK WNT5B

7.12e-0516611558e2faca6a2e76a625de04d6098aa6f98911945c6
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADAMTS10 MET P2RY11 NFXL1 MUC5AC

7.12e-0516611554586d6725403f879fc96f67be579022587ce1906
ToppCellfacs-Heart-RA-18m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWF DSG2 TEK ADH1A MEGF6

7.53e-05168115506dc5b2d356d3a9454b10bba6f3b9ead2a0a7d46
ToppCellfacs-Heart-RA-18m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWF DSG2 TEK ADH1A MEGF6

7.53e-0516811551002f058a340763e3d8de0bd1f0547a903526ec6
ToppCellPND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PRPS2 LRP8 MET ASXL3 LRP2

7.97e-0517011554ce81608111b9ee7cb974dad2c182f38db3dcd79
ToppCellfrontal_cortex-Non-neuronal-leptomeningeal_cell|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

LAMA1 LAMB2 SVEP1 EGFLAM NOTCH2

8.19e-0517111552e43fb129ee9bdc3b31febc43c10f959bf0f4a7d
ToppCell3'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-D_cells_(SST+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAM29 MET CLEC4G DHRS2 PRDM14

8.19e-051711155fa5cc720bd0045d0307439be547b41d56def5b43
ToppCellfrontal_cortex-Non-neuronal-leptomeningeal_cell-VLMC|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

LAMA1 LAMB2 SVEP1 EGFLAM NOTCH2

8.19e-051711155e219a1aa59a96e4bc3e2eacf985679174a51de41
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

USP53 LAMA3 MET SLC12A1 MEGF11

8.42e-051721155bd73fd3520064d430a153cfdd5c2858b6c184c59
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

USP53 LAMA3 MET SLC12A1 MEGF11

8.42e-05172115547ee78ed3ba6516dad8f12dbf70bca5ed1c60aff
ToppCellfacs-Heart-RA-24m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWF DSG2 TEK ADH1A MEGF6

8.89e-05174115542dfb6f42b72e40e203b3ef341117bccf3553d54
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

USP53 LAMA3 MET SLC12A1 MEGF11

8.89e-051741155583955b4db442ba0583e2312af242f050547f9d6
ToppCellfacs-Heart-RA-24m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWF DSG2 TEK ADH1A MEGF6

8.89e-051741155f04edf2ca6788875c9918611e416fb739924382e
ToppCell343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)-|343B / Donor, Lineage, Cell class and subclass (all cells)

WNT2B SVEP1 ADH1A ADH1B FBLN1

9.38e-0517611552e94bbe17c0bb65dc58b4ebc0cb829258bd7373b
ToppCell343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)|343B / Donor, Lineage, Cell class and subclass (all cells)

WNT2B SVEP1 ADH1A ADH1B FBLN1

9.38e-051761155f33ab41d121b59d871ad7d48ca021524a027d2ef
ToppCellfacs-Liver-Non-hepatocytes|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4D TEK ITGB2 FBLN1 PLP1

9.63e-051771155f73ed860685a724591d0f543a9ac4e868aff92f5
ToppCellfacs-Spleen-nan-3m-Lymphocytic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENPP2 ADH1A FBLN1 PLP1 NOTCH2

1.04e-04180115587fb1fdbc49c808bb5f6fe9fb747057b45fa78d0
ToppCell(3)_Chondrocytes-(32)_Chondro-prehyper-2|(3)_Chondrocytes / Cell class and subclass of bone marrow stroma cells in homeostatis

USP53 VLDLR ENPP2 RNF17 WNT5B

1.04e-041801155708a5c89b9337e281fce4f482892a1c1766c7812
ToppCellfacs-Spleen-nan-3m|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENPP2 ADH1A FBLN1 PLP1 NOTCH2

1.04e-041801155c0c3144011856d005aebd5cdc79f89fee32083a8
ToppCelldroplet-Lung-1m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VWF LAMA3 LAMB2 HEG1 SPRY4

1.07e-041811155136b0c60680068838d184d32aa99d7bea8718dbc
ToppCellfacs-Heart-LV-3m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DTX3 SSPOP SPRY4 CLEC4G EGFLAM

1.07e-0418111551db1eb7d330a7e5090994007ae287e11f0a74450
ToppCellfacs-Heart-LV-3m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DTX3 SSPOP SPRY4 CLEC4G EGFLAM

1.07e-04181115506174ce9240c9261c0f51a1b0d875335d60722e5
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWF WNT5A LAMB2 TEK HEG1

1.10e-041821155e6a734fb29105093d4cbfc3d0619a825b66da034
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWF WNT5A LAMB2 TEK HEG1

1.10e-041821155ccc313ecc0bfd8e2c6bb83a565b427b2310485ec
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo-OPC|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TEK SPRY4 LRP4 MEGF11 NOTCH2

1.10e-0418211553cc61f5f7ad4a81eba3daf65e122880b5af3adc0
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWF WNT5A LAMB2 TEK HEG1

1.10e-041821155b9f758961fb4a586ae86fa0b25edb8ce4616d644
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TEK SPRY4 LRP4 MEGF11 NOTCH2

1.10e-0418211555d909e4b5f662905bf1be9c686bbddc3e87d2be9
ToppCelldroplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VWF WNT2B NEU3 TEK MEGF6

1.13e-0418311556f8f997ffc9eaebca2683de125b6069d07c07d26
ToppCellBasal|World / shred by cell class for mouse tongue

DSG2 LAMA3 HEG1 MEGF6 FURIN

1.13e-041831155c6729a207526ff4aa48176207b9353176f631fea
ToppCellfacs-Mammary_Gland-Mammary_Gland-18m-Mesenchymal|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENPP2 TEK SVEP1 ADH1A FBLN1

1.13e-0418311555cfcd589a480e67654d3d94e71916f122150db10
ToppCellfacs-Mammary_Gland-Mammary_Gland-18m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENPP2 TEK SVEP1 ADH1A FBLN1

1.13e-041831155c3ea8d3b916ffcaca3156e0d77a952724554c4ab
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

VWF ENPP2 TEK HEG1 SPRY4

1.13e-041831155dc19857b66dcadbf7c87de91f7b1f4e8ef2857ed
ToppCelldroplet-Heart-4Chambers-18m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWF DSG2 TEK ADH1A MEGF6

1.13e-0418311556c4a09c02e30e1f24dde39f8cb8c5b453826ee2e
ToppCellfacs-Mammary_Gland-Mammary_Gland-18m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENPP2 TEK SVEP1 ADH1A FBLN1

1.13e-04183115581003ddc24164959dd41bb12fcac72638789b8f2
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

VWF ENPP2 TEK HEG1 SPRY4

1.13e-0418311554759560e5b4f4e5a00e5f933e3451a27c7c4aefe
ToppCellfacs-Heart-RA-18m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DTX3 WNT5B SPRY4 CLEC4G EGFLAM

1.13e-0418311550f02136359787bd78146617990968baa47a65d86
ToppCellfacs-Heart-RA-18m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DTX3 WNT5B SPRY4 CLEC4G EGFLAM

1.13e-0418311552f0dcc65ad4d90ef946919b4462280fdd20c5ea0
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWF DSG2 ADH1A WIZ MEGF6

1.13e-041831155b0b5a41f1a40f9c946d0dc8b67eaccdd9f9b73a5
ToppCell(7)_DC_activated|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

DSG2 ENPP2 WNT5A WNT5B SLC12A1

1.16e-041841155b89871a3e36fde6daa68daf116f8c8d587554c0f
ToppCellfacs-Heart-LA-18m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWF ADH1A ATXN7L3 HEG1 MEGF6

1.19e-0418511551ecfca049c0c1110fd1b2256db7cb7abda6afb04
ToppCellfacs-Heart-LA-18m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWF ADH1A ATXN7L3 HEG1 MEGF6

1.19e-041851155b6df1412b579d40ed5df806f9c54bd1fbb9a1e15
ToppCellfacs-Thymus-Epithelium-24m-Mesenchymal-fibroblast|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIP6 ENPP2 SVEP1 FBLN1 LRP4

1.19e-041851155eaa54b76743628c89b4310be57b87fa92b75fd37
ToppCellfacs-Thymus-Epithelium-24m-Mesenchymal-fibroblast|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIP6 ENPP2 SVEP1 FBLN1 LRP4

1.19e-041851155f7f4c921d248c637351e2e882589b99ba7f04b66
ToppCellfacs-Thymus-Epithelium-24m-Mesenchymal|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIP6 ENPP2 SVEP1 FBLN1 LRP4

1.19e-041851155ff38a15af3dec36d9993f06623591872b5d1da9a
ToppCell5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VLDLR WNT2B ADH1B ADAMTS10 FBLN1

1.22e-041861155f07e0c0d9c80ac9d8d679950e7d0c812becb85a3
ToppCelldroplet-Lung-1m-Endothelial-arterial_endothelial|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VWF LAMA3 LAMB2 TEK MEGF6

1.22e-041861155ffbc78058be8f0dc2e0335cc4c3195a636d17721
ToppCelldroplet-Lung-1m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VWF LAMA3 LAMB2 TEK MEGF6

1.22e-041861155ed924852cd7132c8f6703522037dc22bd2c83193
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D175|Adult / Lineage, Cell type, age group and donor

ENPP2 SVEP1 ADH1B FBLN1 ASXL3

1.25e-041871155e15d2967aac248da3517bc2c7d1beaa1d5a0aa7f
ComputationalGenes in the cancer module 514.

ADH1A ADH1C DHRS2

3.21e-0510713MODULE_514
Drug4-Iodopyrazole

ADH1A ADH1B ADH1C

1.22e-0731143DB02721
DrugFomepizole

ADH1A ADH1B ADH1C

4.87e-0741143DB01213
DrugEthanol

ADH1A ADH1B ADH1C

4.22e-0671143DB00898
Drugazoxystrobin

AIRE STAM ADH1A ADH1B ADH1C NOTCH2

5.36e-06881146CID003034285
Drug2-butoxyethanol

AASDH ADH1A ADH1B ADH1C

5.86e-06241144CID000008133
Drugtrichostatin A; Down 200; 0.1uM; ssMCF7; HG-U133A

ASXL1 TRIP6 NSD1 ZNF710 MET THADA WIZ ZFR

5.89e-061931148413_DN
DrugAmphotericin B [1397-89-3]; Up 200; 4.4uM; MCF7; HT_HG-U133A

ZNF710 MET FBLN1 HEG1 MEGF6 FDX1 LONRF3 PLP1

6.60e-0619611485404_UP
DrugN-heptylformamide

ADH1A ADH1B ADH1C

6.72e-0681143CID000347402
DrugAmphotericin B [1397-89-3]; Down 200; 4.4uM; PC3; HT_HG-U133A

ITGB2 ZNF710 MET ZSCAN32 FBLN1 FURIN DHRS2 ZC3HAV1

7.65e-0620011486303_DN
Drug4-methylpiperazine-2,6-dione

AASDH ADH1A ADH1B ADH1C

8.19e-06261144CID000124723
Drug2-NA

ADH1A ADH1B ADH1C

1.00e-0591143CID000074128
Drug(3R,7R)-17-(6-hydroxy-1,5-dimethyl-hexyl)-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol

ADH1A ADH1B ADH1C

1.00e-0591143CID000440672
DrugAC1L9M5J

WNT3 WNT5A WNT6 WNT2B AIRE LRP8 WNT5B LRP6

1.58e-052211148CID000448615
DrugAC1L1G72

LAMA1 LAMA3 LAMB2

1.96e-05111143CID000003553
DrugAC1L1J0I

ADH1A ADH1B ADH1C

2.60e-05121143CID000030201
Drughexa-2,4-dien-1-ol

ADH1A ADH1B ADH1C

2.60e-05121143CID000008104
Drug2-naphthaldehyde

ADH1A ADH1B ADH1C

3.37e-05131143CID000006201
Drug3-methylbutanal

ADH1A ADH1B ADH1C

3.37e-05131143CID000011552
Drugnaphthalenemethanol

ADH1A ADH1B ADH1C

4.27e-05141143CID000020908
DrugSecurinine [5610-40-2]; Up 200; 18.4uM; HL60; HT_HG-U133A

STAM2 AIRE ZNF407 FBLN1 DHRS2 PLP1 ZNF222

4.73e-0518911472729_UP
Drug6-[(3R,7R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methylheptanal

ADH1A ADH1B ADH1C

5.32e-05151143CID000440673
DrugCephapirin sodium salt [24356-60-3]; Down 200; 9uM; MCF7; HT_HG-U133A

SEMA4D ZNF250 MET ZSCAN32 WIZ FURIN LRP6

5.95e-0519611473471_DN
DrugTocopherol (R,S) [10191-41-0]; Up 200; 9.2uM; MCF7; HT_HG-U133A

VLDLR RNF17 SVEP1 ZNF710 HEG1 FURIN MUC5AC

5.95e-0519611473256_UP
DrugGrgds

VWF LAMA3 LAMB2 ITGB2 FBLN1

6.13e-05831145CID000123811
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; HL60; HG-U133A

SEMA4D TRIP6 ENPP2 ZNF710 THADA MZF1 ZFR

6.15e-0519711471732_DN
DrugPHA-00745360 [351320-33-7]; Up 200; 1uM; PC3; HT_HG-U133A

SVEP1 WIZ MEGF6 FDX1 LRP4 DHRS2 PRDM14

6.35e-0519811474562_UP
DrugS(-)Eticlopride hydrochloride [97612-24-3]; Up 200; 10.6uM; MCF7; HT_HG-U133A

DTX3 ZNF407 MET HEG1 WIZ MUC5AC PLP1

6.35e-0519811473393_UP
DrugProcyclidine hydrochloride [1508-76-5]; Up 200; 12.4uM; PC3; HT_HG-U133A

WNT3 AIRE ZNF407 RNF17 ZNF710 WNT5B PRDM14

6.35e-0519811474233_UP
Drugphenoxyethanol

ADH1A ADH1B ADH1C

6.53e-05161143CID000031236
Drugnaphthaldehyde

ADH1A ADH1B ADH1C

6.53e-05161143CID000006195
Drug2-propylpentanoic acid; Down 200; 2000uM; MCF7; HG-U133A

ASXL1 SVEP1 ZNF710 THADA MZF1 ZFR PRDM14

6.55e-051991147346_DN
DrugChlormezanone [80-77-3]; Up 200; 14.6uM; MCF7; HT_HG-U133A

USP53 VLDLR DTX3 ITGB2 WNT5B MZF1 PRDM14

6.55e-0519911475697_UP
DrugAC1L1AO2

PRPS2 PPAT PRPS1

9.44e-05181143CID000001073
DrugC x F

ADH1A ADH1B ADH1C

1.12e-04191143CID000013017
DiseaseLeukemia, Myelocytic, Acute

NSD1 MET KMT2C SPRY4 ASXL2 NOTCH2

4.35e-051731086C0023467
Diseasealcohol dependence measurement

ADH1A ADH1B ADH1C BPTF

5.01e-05551084EFO_0007835
DiseaseSkin Ulcer

LAMA3 ITGB2

7.93e-0541082C0037299
DiseaseAcute Myeloid Leukemia, M1

NSD1 MET KMT2C SPRY4 ASXL2

9.90e-051251085C0026998
DiseaseAcute Myeloid Leukemia (AML-M2)

NSD1 MET KMT2C SPRY4 ASXL2

9.90e-051251085C1879321
DiseaseNon-alcoholic Fatty Liver Disease

VLDLR LAMA1 ADH1A ADH1B

1.29e-04701084C0400966
DiseaseNonalcoholic Steatohepatitis

VLDLR LAMA1 ADH1A ADH1B

1.29e-04701084C3241937
DiseaseAlcohol dependence

ADH1B ADH1C

1.32e-0451082cv:C0001973
DiseaseALCOHOL DEPENDENCE

ADH1B ADH1C

1.32e-0451082103780
DiseaseColorectal Carcinoma

LAMA1 ADAM29 STAM ADH1B KMT2C LRP2 NR3C2 DHRS2 ZNF572 PRPS1

2.60e-0470210810C0009402
Diseasealcohol use disorder measurement, longitudinal alcohol consumption measurement

ADH1A ADH1B ADH1C

3.38e-04371083EFO_0007645, EFO_0009458
DiseaseAlcohol Use Disorder

VWF ADH1B ADH1C

5.66e-04441083C0001956
Diseasealcohol dependence

ADH1A ADH1B ADH1C ASXL3 MUC5AC

5.78e-041831085MONDO_0007079
Diseaseintraocular pressure measurement

WNT3 WNT2B THADA ZNF516 LRP4 HERC2 TMEM181 TRIM51G

5.79e-045091088EFO_0004695
Diseaseallergic rhinitis (biomarker_via_orthology)

ITGB2 MUC5AC

5.86e-04101082DOID:4481 (biomarker_via_orthology)
Diseasedementia (is_implicated_in)

VLDLR LRP8

8.55e-04121082DOID:1307 (is_implicated_in)
Diseasefeeling emotionally hurt measurement

WNT3 LRP8 FURIN

1.15e-03561083EFO_0009599
Diseasepolycystic kidney disease (implicated_via_orthology)

STAM2 STAM

1.17e-03141082DOID:0080322 (implicated_via_orthology)
DiseaseProteinuria

VWF LRP2

1.35e-03151082HP_0000093
Diseasecaffeine measurement

LAMB2 MEGF11

1.35e-03151082EFO_0021177
Diseasealcohol use disorder (is_implicated_in)

ADH1B ADH1C

1.54e-03161082DOID:1574 (is_implicated_in)
Diseasepro-hydroxy-pro measurement

WNT5A NR3C2

1.54e-03161082EFO_0021132
DiseaseBladder Neoplasm

BPTF KMT2C ASXL2 NOTCH2

1.78e-031401084C0005695
DiseaseMalignant neoplasm of urinary bladder

BPTF KMT2C ASXL2 NOTCH2

1.82e-031411084C0005684
Diseasedehydroepiandrosterone sulphate measurement

THADA ZNF394 LINC02914

2.01e-03681083EFO_0007001
Diseaseintellectual disability (implicated_via_orthology)

UBR4 PSMB1 PLP1

2.66e-03751083DOID:1059 (implicated_via_orthology)
Diseasesex interaction measurement, cerebral amyloid angiopathy

ADH1B ADH1C

2.66e-03211082EFO_0006790, EFO_0008343
Diseasegastric ulcer (biomarker_via_orthology)

TEK MUC5AC

2.66e-03211082DOID:10808 (biomarker_via_orthology)
DiseaseAlcoholic Intoxication, Chronic

VWF ADH1A LRP8 ADH1B ADH1C

3.10e-032681085C0001973
Diseasegranulocyte percentage of myeloid white cells

DAGLB THADA SPRY4 ZNF516 SCUBE3

3.10e-032681085EFO_0007997
Diseasewhite matter microstructure measurement

SPIRE2 WNT3 ITGB2 BPTF LRP2 ASXL2

3.17e-033901086EFO_0005674
Diseasevenous thromboembolism, tissue plasminogen activator measurement

VWF LRP4

3.19e-03231082EFO_0004286, EFO_0004791
DiseaseMyasthenic Syndromes, Congenital

LAMB2 LRP4

3.48e-03241082C0751882
Diseasealcohol use disorder measurement, alcohol dependence

ADH1B ADH1C

3.48e-03241082EFO_0009458, MONDO_0007079

Protein segments in the cluster

PeptideGeneStartEntry
LTDGSTCAFGLCCKD

ADAM29

431

Q9UKF5
DAGCSVGLGKVHCSC

ERC2-IT1

21

O76042
SGICDEASCIHGGTC

EGFLAM

566

Q63HQ2
EASCIHGGTCTAIKA

EGFLAM

571

Q63HQ2
LCCHEACGTSVIVGV

ADH1A

281

P07327
CEGTLACSTCHLIFE

FDX1

106

P10109
LCCHEACGTSVIVGV

ADH1B

281

P00325
LCCHEACGTSVIVGV

ADH1C

281

P00326
ICIGCVDGNLLCFTH

AASDH

951

Q4L235
CHKLGDLLCCETCSA

BPTF

396

Q12830
AFCHDDCIGPSKLCV

ASXL1

1521

Q8IXJ9
SCLGFCFEVHRAVKC

ATXN7L3

31

Q14CW9
FCHDDCIGPSKLCVS

ASXL2

1416

Q76L83
IVCKGCGAFCHDDCI

ASXL3

2221

Q9C0F0
CGAFCHDDCIGPSKL

ASXL3

2226

Q9C0F0
ICVSGECKHVGCDRV

ADAMTS10

671

Q9H324
VCGDGTDVLRCTHCA

AIRE

436

O43918
KARVGEGACSDCLVC

C16orf46

91

Q6P387
CAVCGTACKHLALSD

RNF212B

36

A8MTL3
QCCGAFHLECLGLTE

NSD1

1561

Q96L73
LTLTVCECLHGSGCR

DSG2

586

Q14126
HLGFSVDDLGCCKVI

MMADHC

251

Q9H3L0
GKCVNTDGAFHCECL

NOTCH2

431

Q04721
CDHISGKCTCRTGFT

MEGF11

761

A6BM72
EACIKCLGTADHGLA

P2RY11

186

Q96G91
AFCKHLGATIKCCEE

KMT2C

286

Q8NEZ4
KICLVCGDEASGCHY

NR3C2

601

P08235
CGHTLCESCVDLLFV

MNAT1

26

P51948
CKCHKAGTVSGTGEC

LAMA3

631

Q16787
DSCDKVLECGIHRCS

NFXL1

416

Q6ZNB6
TGCFLLCNTGHKCVF

GK3P

281

Q14409
CEAECLTFEVKIGGC

DEFB107A

41

Q8IZN7
TGSLHCVCCTEDGEV

HERC2

4256

O95714
TGCGKTFVSLLICEH

DDX58

266

O95786
PCGSLDFIHTCEKLC

NFX1

631

Q12986
DFIHTCEKLCHEGDC

NFX1

636

Q12986
HICLVKGDGTTRCSC

LRP6

1216

O75581
CQCSHEGALSSLCEK

LAMB2

831

P55268
TCLDLSCCKLGDEHE

LRRC42

176

Q9Y546
THECVQEPFGAKCLC

LRP2

1361

P98164
AICTCTHGKLSCIGG

MUC5AC

781

P98088
CTDLDGVALCQCKSG

HEG1

1191

Q9ULI3
GLACCFGICAISHLE

MROH1

686

Q8NDA8
CGHKCENTLGSYLCS

FBLN1

411

P23142
RSLCHGKGFLECGIC

ITGB2

456

P05107
ICAVGHGVAALCCAT

GATD1

121

Q8NB37
TLEKCRHSFCEGCIT

DTX3

176

Q8N9I9
GALCAIKSFVSHCGD

HEATR5A

611

Q86XA9
CCCIGKDDHTRVAFS

DAGLB

201

Q8NCG7
CVVCEEGFSLHQKSC

FURIN

596

P09958
LKFGTLDCTVHEGLC

DNAJC10

501

Q8IXB1
KALEHCGGVDFLVCS

DHRS2

106

Q13268
GCDSKCHDAATGVHC

SCUBE3

246

Q8IX30
DKTVIGCSGFHGDCL

PSMB1

76

P20618
CCHDFDELCLKTARG

ENPP2

86

Q13822
HALTLTKARCCGECS

LINC02914

56

Q52M58
GCSHICTDLKIGFEC

LRP8

346

Q14114
AECSASLCFHGGRCV

MEGF6

126

O75095
CHDKCVRSEECLSGT

MET

541

P08581
ELDKHFLLCEACGKC

SPRY4

151

Q9C004
TCLGCLVECIGVEHI

THADA

456

Q6YHU6
VCHGGAFSCSLVDCQ

SSPOP

4911

A2VEC9
KEDDGCSCSICGKIF

PRDM14

541

Q9GZV8
VSIVCGKSVDFCCSH

PNPLA5

56

Q7Z6Z6
GHCDSVTGECLKCLG

LAMA1

861

P25391
DCCCKTFLLTVKHLG

NEPRO

151

Q6NW34
HDSCDSCKEGGDLLC

PHF12

56

Q96QT6
THAFTKNSGLCICCE

SLC12A1

701

Q13621
TCEVCGACFETRKGL

WIZ

871

O95785
AFCGKHGTCEDCVLA

SEMA4D

501

Q92854
CGTHTGHFECICEKG

SVEP1

296

Q4LDE5
SEHLFICEECGRCKC

SPRY3

141

O43610
LGALKEEVGDCHSCC

CLEC4G

81

Q6UXB4
LFGCLFECGTKQECE

NEU3

381

Q9UQ49
HVCQGDACIFCALKT

USP53

66

Q70EK8
CCECGKSFGLSSHLI

ZNF572

386

Q7Z3I7
CGHAFCELCLLMTEE

RNF17

51

Q9BXT8
CEVPTCSLCKVFGAH

TRIM54

141

Q9BYV2
CSLCKVFGAHKDCEV

TRIM54

146

Q9BYV2
FICGTCGKALSCHSR

ZNF707

176

Q96C28
VDGDKATCHTCCICG

ZNF516

26

Q92618
GCFTCVVCHRGLDGI

TRIP6

361

Q15654
HIGCYKCEECGLLLS

TRIP6

426

Q15654
HFKCEECGETCHISN

ZNF394

441

Q53GI3
CVECGKCFGRSSHLL

ZNF250

201

P15622
SFCARDKACTHILCG

ZSCAN32

486

Q9NX65
FVALCEKTLCECAGG

VWF

246

P04275
LCVESTECPCVHSGK

VWF

341

P04275
TCAGKCAEIIVAHLG

TMEM181

261

Q9P2C4
HGCVLKDVCSECTSF

SPIRE2

661

Q8WWL2
GLFLLGCVKEDTHCS

TRIM51

376

Q9BSJ1
CGTICHAADKLLSAG

PRPS2

226

P11908
CFEKSGHCTACLTGK

PPAT

496

Q06203
CHVCVECGLDFSTLT

ZNF710

406

Q8N1W2
NVTSHGIDGCDLLCC

WNT3

301

P56703
ACKCHGVSGSCSLKT

WNT5B

216

Q9H1J7
ECKCHGLSGSCALRT

WNT6

221

Q9Y6F9
ILVTGTCHLKCVCYG

SRRD

131

Q9UH36
ACVSNCGKIFHLEVC

STAM

71

Q92783
ACVANCGKIFHLEVC

STAM2

71

O75886
VACKCHGVSGSCSLK

WNT5A

236

P41221
CEKACELHTFGRTCK

TEK

251

Q02763
CGKCHHVCFTKGELQ

ZNF518A

236

Q6AHZ1
GLFLLGCVKEDTHCS

TRIM51G

376

A0A3B3IT33
EGKVIRFHCKLCECS

ZFR

576

Q96KR1
DIHCVDSAGERACKC

ZNF233

386

A6NK53
CGTICHAADKLLSAG

PRPS1

226

P60891
VCCFITKILCAHGGR

ZC3HAV1

6

Q7Z2W4
CTKCGDVFCHSTSLI

ZNF883

351

P0CG24
LKCSICGHLFSSCSD

ZNF407

186

Q9C0G0
CKECGNSFSVVGHLT

ZNF529

536

Q6P280
DGVGVCTVCAKVCHK

UBR4

1686

Q5T4S7
CKGCLVSLSCHLDAE

TRIM50

36

Q86XT4
CTECGKAFCEKSHLI

ZNF300

411

Q96RE9
ECKCHGVSGSCTLRT

WNT2B

236

Q93097
GEKSHTCDECGKSFC

ZNF222

141

Q9UK12
GCSHICKDLVIGYEC

VLDLR

366

P98155
ECGECGKCFHQKGSL

ZNF776

461

Q68DI1
ECRECGKAFCCSSHL

ZNF302

421

Q9NR11
HFTCAVSALGECTCI

LRP4

31

O75096
LSCGHTFCKLCLERG

LONRF3

171

Q496Y0
LFCGCGHEALTGTEK

PLP1

31

P60201
VHTGDKSFGCVECGE

MZF1

506

P28698