| Category | Name | IntersectionWithQuery | PValue | GenesInTerm | GenesInQuery | GenesInTermInQuery | ID |
|---|---|---|---|---|---|---|---|
| GeneOntologyMolecularFunction | monoatomic cation channel activity | 1.34e-05 | 343 | 64 | 8 | GO:0005261 | |
| GeneOntologyMolecularFunction | ligand-gated monoatomic cation channel activity | 8.62e-05 | 140 | 64 | 5 | GO:0099094 | |
| GeneOntologyMolecularFunction | gated channel activity | 9.43e-05 | 334 | 64 | 7 | GO:0022836 | |
| GeneOntologyMolecularFunction | monoatomic ion channel activity | 1.05e-04 | 459 | 64 | 8 | GO:0005216 | |
| GeneOntologyMolecularFunction | metal ion transmembrane transporter activity | 1.15e-04 | 465 | 64 | 8 | GO:0046873 | |
| GeneOntologyMolecularFunction | monoatomic cation transmembrane transporter activity | 2.53e-04 | 664 | 64 | 9 | GO:0008324 | |
| GeneOntologyMolecularFunction | channel activity | 2.63e-04 | 525 | 64 | 8 | GO:0015267 | |
| GeneOntologyMolecularFunction | passive transmembrane transporter activity | 2.66e-04 | 526 | 64 | 8 | GO:0022803 | |
| GeneOntologyMolecularFunction | ligand-gated monoatomic ion channel activity | 3.85e-04 | 193 | 64 | 5 | GO:0015276 | |
| GeneOntologyMolecularFunction | ligand-gated channel activity | 4.23e-04 | 197 | 64 | 5 | GO:0022834 | |
| GeneOntologyMolecularFunction | iron ion transmembrane transporter activity | 5.46e-04 | 11 | 64 | 2 | GO:0005381 | |
| GeneOntologyMolecularFunction | sodium channel activity | 6.20e-04 | 52 | 64 | 3 | GO:0005272 | |
| GeneOntologyMolecularFunction | transporter activity | ABCB7 SLC11A2 SLC22A16 KCND3 SCNN1D SCNN1G HTR3D PKD1L3 MCOLN1 CNGA2 KCNK4 C2CD2L | 7.14e-04 | 1289 | 64 | 12 | GO:0005215 |
| GeneOntologyMolecularFunction | potassium channel activity | 7.60e-04 | 128 | 64 | 4 | GO:0005267 | |
| GeneOntologyMolecularFunction | inorganic cation transmembrane transporter activity | 8.50e-04 | 627 | 64 | 8 | GO:0022890 | |
| GeneOntologyMolecularFunction | monoatomic ion transmembrane transporter activity | 9.13e-04 | 793 | 64 | 9 | GO:0015075 | |
| GeneOntologyMolecularFunction | transmembrane transporter activity | ABCB7 SLC11A2 SLC22A16 KCND3 SCNN1D SCNN1G HTR3D PKD1L3 MCOLN1 CNGA2 KCNK4 | 1.21e-03 | 1180 | 64 | 11 | GO:0022857 |
| GeneOntologyMolecularFunction | ligand-gated sodium channel activity | 1.50e-03 | 18 | 64 | 2 | GO:0015280 | |
| GeneOntologyMolecularFunction | potassium ion transmembrane transporter activity | 2.03e-03 | 167 | 64 | 4 | GO:0015079 | |
| GeneOntologyMolecularFunction | inorganic molecular entity transmembrane transporter activity | 2.81e-03 | 758 | 64 | 8 | GO:0015318 | |
| GeneOntologyMolecularFunction | outward rectifier potassium channel activity | 3.37e-03 | 27 | 64 | 2 | GO:0015271 | |
| GeneOntologyMolecularFunction | Notch binding | 3.37e-03 | 27 | 64 | 2 | GO:0005112 | |
| GeneOntologyMolecularFunction | voltage-gated potassium channel activity | 4.30e-03 | 102 | 64 | 3 | GO:0005249 | |
| GeneOntologyMolecularFunction | intracellularly ligand-gated monoatomic ion channel activity | 5.01e-03 | 33 | 64 | 2 | GO:0005217 | |
| GeneOntologyBiologicalProcess | cellular response to pH | 1.53e-08 | 26 | 64 | 5 | GO:0071467 | |
| GeneOntologyBiologicalProcess | response to pH | 4.21e-07 | 49 | 64 | 5 | GO:0009268 | |
| GeneOntologyBiologicalProcess | sensory perception of sour taste | 2.36e-06 | 9 | 64 | 3 | GO:0050915 | |
| GeneOntologyBiologicalProcess | cellular response to acidic pH | 1.26e-05 | 15 | 64 | 3 | GO:0071468 | |
| GeneOntologyBiologicalProcess | sensory perception of salty taste | 5.66e-05 | 4 | 64 | 2 | GO:0050914 | |
| GeneOntologyBiologicalProcess | response to acidic pH | 7.90e-05 | 27 | 64 | 3 | GO:0010447 | |
| GeneOntologyBiologicalProcess | iron ion transmembrane transport | 1.09e-04 | 30 | 64 | 3 | GO:0034755 | |
| GeneOntologyBiologicalProcess | inorganic cation transmembrane transport | ABCB7 SLC11A2 KCND3 PMPCB SCNN1D SCNN1G HTR3D PKD1L3 MCOLN1 CNGA2 KCNK4 | 1.14e-04 | 922 | 64 | 11 | GO:0098662 |
| GeneOntologyBiologicalProcess | cellular response to vasopressin | 2.62e-04 | 8 | 64 | 2 | GO:1904117 | |
| GeneOntologyBiologicalProcess | response to vasopressin | 2.62e-04 | 8 | 64 | 2 | GO:1904116 | |
| GeneOntologyBiologicalProcess | inorganic ion transmembrane transport | ABCB7 SLC11A2 KCND3 PMPCB SCNN1D SCNN1G HTR3D PKD1L3 MCOLN1 CNGA2 KCNK4 | 2.67e-04 | 1017 | 64 | 11 | GO:0098660 |
| GeneOntologyBiologicalProcess | cellular response to aldosterone | 3.36e-04 | 9 | 64 | 2 | GO:1904045 | |
| GeneOntologyCellularComponent | cation channel complex | 6.72e-06 | 235 | 63 | 7 | GO:0034703 | |
| GeneOntologyCellularComponent | monoatomic ion channel complex | 1.39e-04 | 378 | 63 | 7 | GO:0034702 | |
| Domain | ENaC | 2.04e-04 | 7 | 59 | 2 | IPR004724 | |
| Domain | Na+channel_ASC_CS | 2.71e-04 | 8 | 59 | 2 | IPR020903 | |
| Domain | ASC | 3.48e-04 | 9 | 59 | 2 | PF00858 | |
| Domain | ASC | 3.48e-04 | 9 | 59 | 2 | PS01206 | |
| Domain | Na+channel_ASC | 3.48e-04 | 9 | 59 | 2 | IPR001873 | |
| Domain | PKD_channel | 5.30e-04 | 11 | 59 | 2 | PF08016 | |
| Domain | PKD1_2_channel | 5.30e-04 | 11 | 59 | 2 | IPR013122 | |
| Domain | hEGF | 3.52e-03 | 28 | 59 | 2 | PF12661 | |
| Domain | Ion_trans_dom | 5.62e-03 | 114 | 59 | 3 | IPR005821 | |
| Domain | Ion_trans | 5.62e-03 | 114 | 59 | 3 | PF00520 | |
| Domain | Rossmann-like_a/b/a_fold | 8.15e-03 | 43 | 59 | 2 | IPR014729 | |
| Domain | - | 8.15e-03 | 43 | 59 | 2 | 3.40.50.620 | |
| Pubmed | Molecular cloning and functional expression of a novel amiloride-sensitive Na+ channel. | 1.03e-05 | 3 | 65 | 2 | 7499195 | |
| Pubmed | Identification of Murr1 as a regulator of the human delta epithelial sodium channel. | 2.06e-05 | 4 | 65 | 2 | 14645214 | |
| Pubmed | δβγ-ENaC is inhibited by CFTR but stimulated by cAMP in Xenopus laevis oocytes. | 2.06e-05 | 4 | 65 | 2 | 27941075 | |
| Pubmed | Second transmembrane domain modulates epithelial sodium channel gating in response to shear stress. | 2.06e-05 | 4 | 65 | 2 | 21307123 | |
| Pubmed | δ ENaC: a novel divergent amiloride-inhibitable sodium channel. | 2.06e-05 | 4 | 65 | 2 | 22983350 | |
| Pubmed | Blood pressure and amiloride-sensitive sodium channels in vascular and renal cells. | 2.06e-05 | 4 | 65 | 2 | 24419567 | |
| Pubmed | 2.06e-05 | 4 | 65 | 2 | 26772908 | ||
| Pubmed | 2.06e-05 | 4 | 65 | 2 | 16423824 | ||
| Pubmed | 3.43e-05 | 5 | 65 | 2 | 22683750 | ||
| Pubmed | 3.43e-05 | 5 | 65 | 2 | 8032683 | ||
| Pubmed | 3.43e-05 | 5 | 65 | 2 | 15578212 | ||
| Pubmed | 3.43e-05 | 5 | 65 | 2 | 19359370 | ||
| Pubmed | 3.43e-05 | 5 | 65 | 2 | 30391555 | ||
| Pubmed | A dual-activity topoisomerase complex regulates mRNA translation and turnover. | KIF26A UBR4 PDZD8 SPATA20 GNA12 NUP188 ZFPM1 DHX30 C2CD2L FANCA | 3.69e-05 | 1105 | 65 | 10 | 35748872 |
| Pubmed | 4.40e-05 | 207 | 65 | 5 | 20186120 | ||
| Pubmed | 5.13e-05 | 6 | 65 | 2 | 19812697 | ||
| Pubmed | METTL3 protects METTL14 from STUB1-mediated degradation to maintain m6 A homeostasis. | 7.39e-05 | 231 | 65 | 5 | 36597993 | |
| Pubmed | 7.81e-05 | 44 | 65 | 3 | 19322198 | ||
| Pubmed | A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling. | 8.00e-05 | 974 | 65 | 9 | 28675297 | |
| Pubmed | 1.23e-04 | 9 | 65 | 2 | 29453251 | ||
| Pubmed | Derlin-1 promotes ubiquitylation and degradation of the epithelial Na+ channel, ENaC. | 1.52e-04 | 55 | 65 | 3 | 28137758 | |
| Pubmed | 1.53e-04 | 10 | 65 | 2 | 21642988 | ||
| Pubmed | 1.70e-04 | 57 | 65 | 3 | 34671097 | ||
| Pubmed | Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context. | 2.54e-04 | 1136 | 65 | 9 | 34800366 | |
| Pubmed | USP7 Cooperates with NOTCH1 to Drive the Oncogenic Transcriptional Program in T-Cell Leukemia. | 3.53e-04 | 73 | 65 | 3 | 30224337 | |
| Pubmed | 3.56e-04 | 15 | 65 | 2 | 21406692 | ||
| Pubmed | A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene. | 3.92e-04 | 331 | 65 | 5 | 19490893 | |
| Pubmed | 4.06e-04 | 16 | 65 | 2 | 20647008 | ||
| Pubmed | A High-Density Human Mitochondrial Proximity Interaction Network. | ABCB7 GANAB PMPCB FLAD1 UBR4 MRPS15 PDZD8 NUP188 DHX30 C2CD2L | 4.35e-04 | 1496 | 65 | 10 | 32877691 |
| Pubmed | E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins. | 4.44e-04 | 736 | 65 | 7 | 29676528 | |
| Pubmed | 4.65e-04 | 529 | 65 | 6 | 14621295 | ||
| Pubmed | 4.89e-04 | 534 | 65 | 6 | 35032548 | ||
| Pubmed | Mfrp, a gene encoding a frizzled related protein, is mutated in the mouse retinal degeneration 6. | 5.16e-04 | 18 | 65 | 2 | 12140190 | |
| Pubmed | The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1. | 6.79e-04 | 212 | 65 | 4 | 33853758 | |
| Pubmed | 9.65e-04 | 233 | 65 | 4 | 37704626 | ||
| Pubmed | 9.80e-04 | 234 | 65 | 4 | 36243803 | ||
| Pubmed | Mitochondrial Protein Interaction Mapping Identifies Regulators of Respiratory Chain Function. | 1.06e-03 | 413 | 65 | 5 | 27499296 | |
| Pubmed | Evidence that the transcriptional repressor ICER is regulated via the N-end rule for ubiquitination. | 1.26e-03 | 28 | 65 | 2 | 35227662 | |
| Pubmed | Notch signaling in stomach epithelial stem cell homeostasis. | 1.35e-03 | 29 | 65 | 2 | 21402740 | |
| Pubmed | 1.75e-03 | 33 | 65 | 2 | 19834762 | ||
| Pubmed | 1.75e-03 | 33 | 65 | 2 | 25582440 | ||
| Pubmed | 1.86e-03 | 34 | 65 | 2 | 20189936 | ||
| Cytoband | 9q34.11 | 6.03e-05 | 53 | 65 | 3 | 9q34.11 | |
| Cytoband | 7p22.2 | 8.82e-05 | 10 | 65 | 2 | 7p22.2 | |
| Cytoband | 11q23 | 1.21e-03 | 36 | 65 | 2 | 11q23 | |
| GeneFamily | Sodium channels epithelial | 3.15e-05 | 4 | 42 | 2 | 185 | |
| Coexpression | KLEIN_PRIMARY_EFFUSION_LYMPHOMA_UP | 6.42e-06 | 50 | 63 | 4 | M12993 | |
| Coexpression | MILI_PSEUDOPODIA_HAPTOTAXIS_DN | 3.46e-05 | 681 | 63 | 9 | M5314 | |
| Coexpression | GSE37605_NOD_VS_C57BL6_IRES_GFP_TREG_UP | 4.08e-05 | 159 | 63 | 5 | M8814 | |
| Coexpression | MILI_PSEUDOPODIA_HAPTOTAXIS_DN | 4.43e-05 | 703 | 63 | 9 | MM1055 | |
| ToppCell | facs-Lung-Endomucin_-18m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 5.44e-06 | 173 | 65 | 5 | c31076c725f4cd912c56903592a2d9356ae59f54 | |
| ToppCell | facs-Lung-Endomucin_-18m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 5.44e-06 | 173 | 65 | 5 | a4ed191cfdf6588b7f3672995bf0a4fe9e4b8df6 | |
| ToppCell | Children_(3_yrs)-Immune-alveolar_macrophage_(MARCO_positive)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor | 9.72e-06 | 195 | 65 | 5 | 9d649ac7d2af313481069c95349efc0c68449e2b | |
| Disease | hypokalemic periodic paralysis (implicated_via_orthology) | 1.21e-04 | 8 | 62 | 2 | DOID:14452 (implicated_via_orthology) | |
| Disease | early cardiac repolarization measurement | 3.89e-04 | 14 | 62 | 2 | EFO_0004885 | |
| Disease | ischemia (implicated_via_orthology) | 5.79e-04 | 17 | 62 | 2 | DOID:326 (implicated_via_orthology) | |
| Disease | X-11470 measurement | 7.26e-04 | 19 | 62 | 2 | EFO_0021241 | |
| Disease | Acute monocytic leukemia | 1.37e-03 | 26 | 62 | 2 | C0023465 | |
| Disease | monocyte count | 1.67e-03 | 1320 | 62 | 9 | EFO_0005091 |
| Peptide | Gene | Start | Entry |
|---|---|---|---|
| LARRLGVAESWTRDR | 56 | Q86Y79 | |
| ERRSVIRSTWLARRG | 71 | Q96L58 | |
| VLFLWRSFRSVTSRL | 26 | Q96RT6 | |
| TRDIVSRERVWRTRT | 221 | Q6P1J9 | |
| SRERVWRTRTTILQS | 226 | Q6P1J9 | |
| SRLARQRLLGRSWSV | 881 | Q9Y6K1 | |
| RRGALERAAWTVAVR | 116 | A0A1B0GTL2 | |
| RLRRASWVTRGATEA | 111 | Q8NCL9 | |
| VRLSQSLLELWRRRG | 411 | Q7L2E3 | |
| TINREATRLRSRWLT | 1061 | Q7L2E3 | |
| VGLTVRRFWDSLLRL | 116 | Q569K6 | |
| RQRGRVISLWERLEF | 336 | Q9GZU1 | |
| ARVVLSSAARRRLWG | 6 | O75439 | |
| VSGRRFQTWRTTLER | 46 | Q9UK17 | |
| RAVTSSRRGLLWRLR | 21 | Q5T9C9 | |
| WEISRSSITLERRLG | 256 | P09769 | |
| TTIGNWLRVVSRRTR | 251 | Q9NYG8 | |
| FRELRDTALTRRWVT | 106 | Q8NEN9 | |
| RERIDRAETLGRTWS | 1561 | Q92817 | |
| LDRLVWRNSIRSSFI | 136 | Q8N4B4 | |
| RRIRARLSLATGLSW | 101 | Q8IX07 | |
| ISWLFRLIEERRERT | 496 | Q9ULI4 | |
| WSRFARVVLTRSIAI | 406 | P49281 | |
| LLRRLRRLSWGSTAV | 11 | Q9BRR3 | |
| GSRFVWNLTVSTLRR | 16 | Q9Y2L6 | |
| TRYWARVRVRTSRTG | 406 | P32927 | |
| RELGVWRSLLRLRAT | 61 | O14523 | |
| RWTKRITGLTISDLR | 271 | Q8TD84 | |
| IFRRRLQALTSGWSV | 1051 | O15360 | |
| WTQDLRTRVVLRIGS | 111 | P08236 | |
| RLLSLWREVVTFRRH | 176 | Q9BV73 | |
| ALWRDSGIREAFSRR | 156 | Q03113 | |
| LWTTRADGRVRLRID | 81 | Q96GR2 | |
| VFRRRWSVGSDDLVL | 6 | Q9Y4D2 | |
| VLATVLLTLRAWRRG | 321 | Q6UY11 | |
| RSRLSRIWLEKTRVF | 16 | Q8NFF5 | |
| RGKTRLFWLLRVVTS | 46 | Q1HG43 | |
| TVRTASETSLRLRWV | 1181 | Q7Z5N4 | |
| VIYTWRSRDLRREVL | 286 | O95136 | |
| TLVLGGRRLRRAWFS | 721 | P51172 | |
| VSRGRLRRLLWIGFT | 46 | P51170 | |
| VLVSVGRSEWFVFRR | 36 | Q96BR1 | |
| LRSWSRAIDRRVLDF | 181 | P0C091 | |
| MLRVAWRTLSLIRTR | 1 | P82914 | |
| SLVDRWIRSRLTEAV | 981 | P26640 | |
| SDRLGRRVVLWATSS | 176 | Q86VW1 | |
| RRRSWASLVLAFLGV | 11 | Q14697 | |
| RLRVISRTLSRAWDE | 1576 | Q7Z443 | |
| RLSRLALGSEAWRRV | 276 | Q9BY78 | |
| TRTLLTFFDLAWRLR | 41 | P0DMW4 | |
| TRTLLTFFDLAWRLR | 41 | P0DMW5 | |
| ARVLSLTLRVGLWVR | 1316 | Q99466 | |
| TFSRWKTLLSRRVVD | 291 | Q8IW75 | |
| AFTVAVTRWRTRFRI | 306 | O75027 | |
| RTSFRTRREWVLLGI | 186 | Q70Z44 | |
| FRRIVRLVGIIREWA | 66 | Q16280 | |
| SRWSLRAAGRLVSIR | 156 | Q86YL5 | |
| TVLWRRLSTFGRRGS | 81 | A0A1B0GVG6 | |
| LREALTTGFVRRLLW | 531 | Q9BRG2 | |
| RVGFRTVLLRIREQW | 191 | Q8TB22 | |
| AELRGIRWTSSLRRE | 61 | Q7Z410 | |
| RSSRELWTILLGRSA | 11 | Q5SRE5 | |
| FLRRLITSLGRSRLW | 1536 | Q8N9V7 | |
| RLVVTSSRDTTFRLW | 336 | Q9Y2I8 | |
| WRATRVEILRRLLVT | 5051 | Q5T4S7 | |
| LFGVEASGRRIWIRR | 461 | O95932 | |
| VRWSETSVERRSDRR | 206 | O15321 |