Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	catalytic activity, acting on a nucleic acid	DHX36 HENMT1 RARS1 IGHMBP2 POLR2B RPP38 EXOSC3 DHX57 EME2 NIPBL	3.15e-05	645	63	10	GO:0140640
GeneOntologyMolecularFunction	catalytic activity, acting on RNA	DHX36 HENMT1 RARS1 IGHMBP2 POLR2B RPP38 EXOSC3 DHX57	4.80e-05	417	63	8	GO:0140098
GeneOntologyMolecularFunction	cytoskeleton-nuclear membrane anchor activity	SYNE1 SYNE2	9.74e-05	5	63	2	GO:0140444
GeneOntologyMolecularFunction	ATP hydrolysis activity	DHX36 DNAH12 MDN1 IGHMBP2 NVL DHX57 TAP1	4.65e-04	441	63	7	GO:0016887
GeneOntologyMolecularFunction	ribonucleoside triphosphate phosphatase activity	DHX36 DNAH12 MDN1 IGHMBP2 LRRK2 NVL DHX57 TAP1 EFTUD2	6.90e-04	775	63	9	GO:0017111
GeneOntologyMolecularFunction	single-stranded DNA binding	DHX36 LRPPRC CTC1 IGHMBP2	8.50e-04	134	63	4	GO:0003697
GeneOntologyMolecularFunction	pyrophosphatase activity	DHX36 DNAH12 MDN1 IGHMBP2 LRRK2 NVL DHX57 TAP1 EFTUD2	1.21e-03	839	63	9	GO:0016462
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	DHX36 DNAH12 MDN1 IGHMBP2 LRRK2 NVL DHX57 TAP1 EFTUD2	1.22e-03	840	63	9	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	DHX36 DNAH12 MDN1 IGHMBP2 LRRK2 NVL DHX57 TAP1 EFTUD2	1.22e-03	840	63	9	GO:0016818
GeneOntologyBiologicalProcess	piRNA processing	TDRD5 HENMT1 GPAT2	3.64e-05	22	61	3	GO:0034587
GeneOntologyBiologicalProcess	regulation of DNA metabolic process	DHX36 SUPT20HL1 CTC1 TIPIN APAF1 EXOSC3 NVL SUPT20HL2 SPIDR	3.92e-05	564	61	9	GO:0051052
GeneOntologyCellularComponent	intracellular protein-containing complex	SUPT20HL1 PRAMEF33 PRAMEF10 RARS1 POLR2B RPP38 TTI1 RICTOR SUPT20HL2 EME2 CRBN	1.39e-04	972	63	11	GO:0140535
GeneOntologyCellularComponent	nuclear outer membrane	LRPPRC SYNE1 SYNE2	2.38e-04	40	63	3	GO:0005640
GeneOntologyCellularComponent	TORC2 complex	TTI1 RICTOR	3.17e-04	9	63	2	GO:0031932
GeneOntologyCellularComponent	microtubule organizing center attachment site	SYNE1 SYNE2	4.83e-04	11	63	2	GO:0034992
GeneOntologyCellularComponent	meiotic nuclear membrane microtubule tethering complex	SYNE1 SYNE2	4.83e-04	11	63	2	GO:0034993
GeneOntologyCellularComponent	nuclear membrane protein complex	SYNE1 SYNE2	4.83e-04	11	63	2	GO:0106083
GeneOntologyCellularComponent	nuclear membrane microtubule tethering complex	SYNE1 SYNE2	4.83e-04	11	63	2	GO:0106094
GeneOntologyCellularComponent	TOR complex	TTI1 RICTOR	5.79e-04	12	63	2	GO:0038201
GeneOntologyCellularComponent	nuclear protein-containing complex	CTC1 SYNE1 TIPIN POLR2B SYNE2 RPP38 EXOSC3 NVL NIPBL PCID2 NUP205 EFTUD2	7.37e-04	1377	63	12	GO:0140513
GeneOntologyCellularComponent	nuclear chromosome	NCAPD3 LRPPRC TIPIN SPIDR EME2	1.01e-03	254	63	5	GO:0000228
GeneOntologyCellularComponent	nuclear exosome (RNase complex)	EXOSC3 NVL	1.04e-03	16	63	2	GO:0000176
GeneOntologyCellularComponent	dendritic shaft	CNIH2 PREX1 CNIH3	1.45e-03	74	63	3	GO:0043198
GeneOntologyCellularComponent	organelle outer membrane	LRPPRC SYNE1 SYNE2 LRRK2 GPAT2	1.53e-03	279	63	5	GO:0031968
GeneOntologyCellularComponent	outer membrane	LRPPRC SYNE1 SYNE2 LRRK2 GPAT2	1.58e-03	281	63	5	GO:0019867
GeneOntologyCellularComponent	endoplasmic reticulum-Golgi intermediate compartment membrane	CNIH2 TAP1 CNIH3	1.88e-03	81	63	3	GO:0033116
GeneOntologyCellularComponent	exosome (RNase complex)	EXOSC3 NVL	2.36e-03	24	63	2	GO:0000178
GeneOntologyCellularComponent	SAGA complex	SUPT20HL1 SUPT20HL2	2.56e-03	25	63	2	GO:0000124
GeneOntologyCellularComponent	exoribonuclease complex	EXOSC3 NVL	2.99e-03	27	63	2	GO:1905354
GeneOntologyCellularComponent	pole plasm	TDRD5 HENMT1	3.44e-03	29	63	2	GO:0045495
GeneOntologyCellularComponent	germ plasm	TDRD5 HENMT1	3.44e-03	29	63	2	GO:0060293
GeneOntologyCellularComponent	P granule	TDRD5 HENMT1	3.44e-03	29	63	2	GO:0043186
GeneOntologyCellularComponent	AMPA glutamate receptor complex	CNIH2 CNIH3	3.68e-03	30	63	2	GO:0032281
Domain	Cornichon_conserved	CNIH2 CNIH3	3.14e-05	3	61	2	IPR033466
Domain	CORNICHON	CNIH2 CNIH3	3.14e-05	3	61	2	PS01340
Domain	KASH	SYNE1 SYNE2	6.27e-05	4	61	2	PF10541
Domain	KASH	SYNE1 SYNE2	6.27e-05	4	61	2	IPR012315
Domain	KASH	SYNE1 SYNE2	6.27e-05	4	61	2	PS51049
Domain	DUF1908	MAST4 MAST3	6.27e-05	4	61	2	PF08926
Domain	MA_Ser/Thr_Kinase_dom	MAST4 MAST3	6.27e-05	4	61	2	IPR015022
Domain	Cornichon	CNIH2 CNIH3	6.27e-05	4	61	2	PF03311
Domain	Cornichon	CNIH2 CNIH3	6.27e-05	4	61	2	IPR003377
Domain	Cornichon	CNIH2 CNIH3	6.27e-05	4	61	2	SM01398
Domain	KASH	SYNE1 SYNE2	6.27e-05	4	61	2	SM01249
Domain	MAST_pre-PK_dom	MAST4 MAST3	6.27e-05	4	61	2	IPR023142
Domain	-	MAST4 MAST3	6.27e-05	4	61	2	1.20.1480.20
Domain	-	NCAPD3 LRRK2 TTI1 RICTOR SPAG6 NIPBL	8.48e-05	222	61	6	1.25.10.10
Domain	AAA+_ATPase	DNAH12 MDN1 IGHMBP2 NVL TAP1	1.07e-04	144	61	5	IPR003593
Domain	AAA	DNAH12 MDN1 IGHMBP2 NVL TAP1	1.07e-04	144	61	5	SM00382
Domain	-	DHX36 DNAH12 MDN1 IGHMBP2 APAF1 LRRK2 NVL DHX57 TAP1 EFTUD2	1.39e-04	746	61	10	3.40.50.300
Domain	ARM-like	NCAPD3 LRRK2 TTI1 RICTOR SPAG6 NIPBL	2.46e-04	270	61	6	IPR011989
Domain	P-loop_NTPase	DHX36 DNAH12 MDN1 IGHMBP2 APAF1 LRRK2 NVL DHX57 TAP1 EFTUD2	3.88e-04	848	61	10	IPR027417
Domain	ARM-type_fold	NCAPD3 LRRK2 TTI1 RICTOR SPAG6 NIPBL	8.20e-04	339	61	6	IPR016024
Domain	HEAT	NCAPD3 SPAG6 NIPBL	9.00e-04	58	61	3	IPR000357
Domain	ATPase_dyneun-rel_AAA	DNAH12 MDN1	9.31e-04	14	61	2	IPR011704
Domain	AAA_5	DNAH12 MDN1	9.31e-04	14	61	2	PF07728
Domain	DUF1605	DHX36 DHX57	1.38e-03	17	61	2	IPR011709
Domain	OB_NTP_bind	DHX36 DHX57	1.38e-03	17	61	2	PF07717
Domain	PDZ	MAST4 PREX1 MAST3 PDZRN4	1.39e-03	148	61	4	SM00228
Domain	-	MAST4 PREX1 MAST3 PDZRN4	1.46e-03	150	61	4	2.30.42.10
Domain	PDZ	MAST4 PREX1 MAST3 PDZRN4	1.50e-03	151	61	4	PS50106
Domain	PDZ	MAST4 PREX1 MAST3 PDZRN4	1.54e-03	152	61	4	IPR001478
Domain	HA2	DHX36 DHX57	1.55e-03	18	61	2	SM00847
Domain	HA2	DHX36 DHX57	1.55e-03	18	61	2	PF04408
Domain	Helicase-assoc_dom	DHX36 DHX57	1.55e-03	18	61	2	IPR007502
Domain	Actinin_actin-bd_CS	SYNE1 SYNE2	2.54e-03	23	61	2	IPR001589
Domain	Spectrin	SYNE1 SYNE2	2.54e-03	23	61	2	PF00435
Domain	ACTININ_2	SYNE1 SYNE2	2.54e-03	23	61	2	PS00020
Domain	ACTININ_1	SYNE1 SYNE2	2.54e-03	23	61	2	PS00019
Domain	Spectrin_repeat	SYNE1 SYNE2	4.02e-03	29	61	2	IPR002017
Domain	Spectrin/alpha-actinin	SYNE1 SYNE2	4.89e-03	32	61	2	IPR018159
Domain	SPEC	SYNE1 SYNE2	4.89e-03	32	61	2	SM00150
Domain	DEXDc	DHX36 IGHMBP2 DHX57	5.44e-03	109	61	3	SM00487
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	DHX36 LRPPRC MDN1 RARS1 PDCD6IP POLR2B RPP38 MIB1 EXOSC3 ISOC1 DHX57 RICTOR BIRC6 NIPBL PCID2 NUP205 EFTUD2	2.37e-10	1353	64	17	29467282
Pubmed	Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.	DHX36 PDCD6IP SYNE1 POLR2B EXOSC3 NVL DHX57 PCID2 NUP205	1.03e-08	332	64	9	25693804
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	DHX36 NCAPD3 MDN1 IGHMBP2 POLR2B RPP38 EXOSC3 NVL DHX57 BIRC6 PCID2 NUP205	1.24e-08	759	64	12	35915203
Pubmed	Transcriptome analysis of mouse stem cells and early embryos.	SUPT20HL1 PRAMEF10 MDN1 POLR2B HECTD4 SUPT20HL2 BIRC6 FRMD4B EFTUD2	2.21e-08	363	64	9	14691545
Pubmed	Interactome of the Autoimmune Risk Protein ANKRD55.	NCAPD3 LRPPRC MDN1 RARS1 MIB1 NUP205 EFTUD2	7.95e-08	197	64	7	31620119
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	DHX36 LRPPRC MDN1 PDCD6IP SYNE2 NVL DHX57 BIRC6 NIPBL NUP205	3.09e-07	653	64	10	22586326
Pubmed	Cracking the egg: molecular dynamics and evolutionary aspects of the transition from the fully grown oocyte to embryo.	TDRD5 HENMT1 AVEN PRAMEF33 PRAMEF10 STK40 BIRC6	2.34e-06	326	64	7	17015433
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	LRPPRC MDN1 RARS1 PDCD6IP SYNE1 POLR2B SYNE2 TAP1 NIPBL NUP205 EFTUD2	2.44e-06	1024	64	11	24711643
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	NCAPD3 MDN1 RARS1 PDCD6IP TTI1 NIPBL EFTUD2	2.64e-06	332	64	7	32786267
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	NCAPD3 MDN1 RARS1 SYNE1 IGHMBP2 POLR2B RPP38 EXOSC3 DHX57 RICTOR PREX1 NIPBL PCID2	2.80e-06	1497	64	13	31527615
Pubmed	Multiple novel nesprin-1 and nesprin-2 variants act as versatile tissue-specific intracellular scaffolds.	SYNE1 SYNE2	3.33e-06	2	64	2	22768332
Pubmed	Nesprins: a novel family of spectrin-repeat-containing proteins that localize to the nuclear membrane in multiple tissues.	SYNE1 SYNE2	3.33e-06	2	64	2	11792814
Pubmed	Nesprin-1 and nesprin-2 regulate endothelial cell shape and migration.	SYNE1 SYNE2	3.33e-06	2	64	2	24931616
Pubmed	Syne-1 and Syne-2 play crucial roles in myonuclear anchorage and motor neuron innervation.	SYNE1 SYNE2	3.33e-06	2	64	2	17267447
Pubmed	Nesprins: tissue-specific expression of epsilon and other short isoforms.	SYNE1 SYNE2	3.33e-06	2	64	2	24718612
Pubmed	Targeted ablation of nesprin 1 and nesprin 2 from murine myocardium results in cardiomyopathy, altered nuclear morphology and inhibition of the biomechanical gene response.	SYNE1 SYNE2	3.33e-06	2	64	2	24586179
Pubmed	Nesprin-1 and -2 are involved in the pathogenesis of Emery Dreifuss muscular dystrophy and are critical for nuclear envelope integrity.	SYNE1 SYNE2	3.33e-06	2	64	2	17761684
Pubmed	Nesprin-1-alpha2 associates with kinesin at myotube outer nuclear membranes, but is restricted to neuromuscular junction nuclei in adult muscle.	SYNE1 SYNE2	3.33e-06	2	64	2	31578382
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	LRRCC1 RICTOR SPIDR BIRC6 PREX1 MAST3 EFTUD2 PDZRN4	3.40e-06	493	64	8	15368895
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	LRPPRC RARS1 PDCD6IP POLR2B SYNE2 RPP38 EXOSC3 TNFAIP3 BIRC6 TAP1 NIPBL PCID2	3.76e-06	1297	64	12	33545068
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	DHX36 LRPPRC PDCD6IP CATSPER2 SYNE1 POLR2B HECTD4 DHX57 NIPBL NUP205 EFTUD2	4.13e-06	1082	64	11	38697112
Pubmed	The Catalytically Inactive Mutation of the Ubiquitin-Conjugating Enzyme CDC34 Affects its Stability and Cell Proliferation.	LRPPRC MDN1 PDCD6IP POLR2B DHX57 NUP205	5.06e-06	237	64	6	29564676
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DHX36 NCAPD3 MAST4 PDCD6IP MIB1 HECTD4 FRMD4B NUP205	5.70e-06	529	64	8	14621295
Pubmed	Defining the membrane proteome of NK cells.	NCAPD3 LRPPRC MDN1 RARS1 PDCD6IP IGHMBP2 NVL BIRC6 TAP1 NUP205 EFTUD2	8.51e-06	1168	64	11	19946888
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	DHX36 LRPPRC RARS1 PDCD6IP POLR2B SYNE2 EXOSC3 ISOC1 BIRC6 NIPBL LETM1 EFTUD2	9.08e-06	1415	64	12	28515276
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	DHX36 NCAPD3 LRPPRC MDN1 RARS1 PDCD6IP SYNE1 POLR2B NIPBL LETM1 NUP205 EFTUD2	9.74e-06	1425	64	12	30948266
Pubmed	Syne-1, a dystrophin- and Klarsicht-related protein associated with synaptic nuclei at the neuromuscular junction.	SYNE1 SYNE2	9.99e-06	3	64	2	10878022
Pubmed	The inner nuclear membrane protein Sun1 mediates the anchorage of Nesprin-2 to the nuclear envelope.	SYNE1 SYNE2	9.99e-06	3	64	2	16079285
Pubmed	The nesprins are giant actin-binding proteins, orthologous to Drosophila melanogaster muscle protein MSP-300.	SYNE1 SYNE2	9.99e-06	3	64	2	12408964
Pubmed	Distinct functional domains in nesprin-1alpha and nesprin-2beta bind directly to emerin and both interactions are disrupted in X-linked Emery-Dreifuss muscular dystrophy.	SYNE1 SYNE2	9.99e-06	3	64	2	17462627
Pubmed	The p38-interacting protein (p38IP) regulates G2/M progression by promoting α-tubulin acetylation via inhibiting ubiquitination-induced degradation of the acetyltransferase GCN5.	SUPT20HL1 SUPT20HL2	9.99e-06	3	64	2	24220028
Pubmed	Structures of FHOD1-Nesprin1/2 complexes reveal alternate binding modes for the FH3 domain of formins.	SYNE1 SYNE2	9.99e-06	3	64	2	33472039
Pubmed	miR-30e Blocks Autophagy and Acts Synergistically with Proanthocyanidin for Inhibition of AVEN and BIRC6 to Increase Apoptosis in Glioblastoma Stem Cells and Glioblastoma SNB19 Cells.	AVEN BIRC6	9.99e-06	3	64	2	27388765
Pubmed	Nesprins anchor kinesin-1 motors to the nucleus to drive nuclear distribution in muscle cells.	SYNE1 SYNE2	9.99e-06	3	64	2	25516977
Pubmed	Upregulation of cornichon transcripts in the dorsolateral prefrontal cortex in schizophrenia.	CNIH2 CNIH3	9.99e-06	3	64	2	23103966
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	NCAPD3 LRPPRC MDN1 PDCD6IP POLR2B SYNE2 EXOSC3 DHX57 TAP1 LETM1 NUP205 EFTUD2	1.08e-05	1440	64	12	30833792
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	LRPPRC MDN1 SYNE1 POLR2B SYNE2 APAF1 MIB1 NVL RICTOR LETM1 MAST3 EFTUD2	1.49e-05	1487	64	12	33957083
Pubmed	SUN1 interacts with nuclear lamin A and cytoplasmic nesprins to provide a physical connection between the nuclear lamina and the cytoskeleton.	SYNE1 SYNE2	2.00e-05	4	64	2	16648470
Pubmed	LINC complexes mediate the positioning of cone photoreceptor nuclei in mouse retina.	SYNE1 SYNE2	2.00e-05	4	64	2	23071752
Pubmed	Nesprins, but not sun proteins, switch isoforms at the nuclear envelope during muscle development.	SYNE1 SYNE2	2.00e-05	4	64	2	20108321
Pubmed	A20 interacts with mTORC2 to inhibit the mTORC2/Akt/Rac1 signaling axis in hepatocellular carcinoma cells.	RICTOR TNFAIP3	2.00e-05	4	64	2	36411371
Pubmed	Nesprin-2 interacts with meckelin and mediates ciliogenesis via remodelling of the actin cytoskeleton.	SYNE1 SYNE2	2.00e-05	4	64	2	19596800
Pubmed	Outer nuclear membrane protein Kuduk modulates the LINC complex and nuclear envelope architecture.	SYNE1 SYNE2	2.00e-05	4	64	2	28716842
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	DHX36 LRPPRC RARS1 PDCD6IP POLR2B DHX57 CDC25B PREX1 PCID2 NUP205 EFTUD2	2.05e-05	1284	64	11	17353931
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	NCAPD3 DNAH12 MDN1 PDCD6IP SYNE2 MIB1 PREX1 NIPBL	2.20e-05	638	64	8	31182584
Pubmed	Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study.	AVEN PDCD6IP TTI1 TNFAIP3 IL1RL2 BIRC6	2.45e-05	313	64	6	20800603
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	DHX36 LRPPRC MDN1 RARS1 PDCD6IP POLR2B MIB1 NIPBL PCID2 NUP205 EFTUD2	2.61e-05	1318	64	11	30463901
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	LRPPRC MDN1 MAST4 PDCD6IP FAM13A SYNE2 RICTOR TNFAIP3 CDC25B	2.73e-05	861	64	9	36931259
Pubmed	Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.	DHX36 LRPPRC RARS1 TIPIN POLR2B RPP38 EXOSC3 ISOC1 DHX57 NUP205 EFTUD2	2.93e-05	1335	64	11	29229926
Pubmed	Poly(ADP-ribosyl)ation of BRD7 by PARP1 confers resistance to DNA-damaging chemotherapeutic agents.	DHX36 NCAPD3 LRPPRC CTC1 IGHMBP2 DHX57 EFTUD2	3.11e-05	486	64	7	30940648
Pubmed	Selective activation of Akt1 by mammalian target of rapamycin complex 2 regulates cancer cell migration, invasion, and metastasis.	RICTOR PREX1	3.32e-05	5	64	2	21339740
Pubmed	Aven, a novel inhibitor of caspase activation, binds Bcl-xL and Apaf-1.	AVEN APAF1	3.32e-05	5	64	2	10949025
Pubmed	Structural requirements for the assembly of LINC complexes and their function in cellular mechanical stiffness.	SYNE1 SYNE2	3.32e-05	5	64	2	18396275
Pubmed	LINC complexes form by binding of three KASH peptides to domain interfaces of trimeric SUN proteins.	SYNE1 SYNE2	3.32e-05	5	64	2	22632968
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	DHX36 NCAPD3 POLR2B RPP38 PCID2 NUP205	3.95e-05	341	64	6	32971831
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	PDCD6IP CTC1 SYNE1 TIPIN MIB1 CDC25B NIPBL CEP43 CRBN EFTUD2	4.66e-05	1155	64	10	20360068
Pubmed	Facilitation of mRNA deadenylation and decay by the exosome-bound, DExH protein RHAU.	DHX36 EXOSC3	4.98e-05	6	64	2	14731398
Pubmed	Cornichon proteins determine the subunit composition of synaptic AMPA receptors.	CNIH2 CNIH3	4.98e-05	6	64	2	23522044
Pubmed	Functional comparison of the effects of TARPs and cornichons on AMPA receptor trafficking and gating.	CNIH2 CNIH3	4.98e-05	6	64	2	20805473
Pubmed	Structural Analysis of Different LINC Complexes Reveals Distinct Binding Modes.	SYNE1 SYNE2	4.98e-05	6	64	2	33058875
Pubmed	TorsinA binds the KASH domain of nesprins and participates in linkage between nuclear envelope and cytoskeleton.	SYNE1 SYNE2	4.98e-05	6	64	2	18827015
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	SYNE1 SYNE2 APAF1 BIRC6 PREX1	6.06e-05	225	64	5	12168954
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	LRPPRC MDN1 PDCD6IP SYNE1 SYNE2 HECTD4 NIPBL LETM1 EFTUD2	6.48e-05	963	64	9	28671696
Pubmed	Protor-2 interacts with tristetraprolin to regulate mRNA stability during stress.	DHX36 RICTOR	6.96e-05	7	64	2	21964062
Pubmed	P-Rex1 links mammalian target of rapamycin signaling to Rac activation and cell migration.	RICTOR PREX1	6.96e-05	7	64	2	17565979
Pubmed	FIH-1, a novel interactor of mindbomb, functions as an essential anti-angiogenic factor during zebrafish vascular development.	DHX36 MIB1	6.96e-05	7	64	2	25347788
Pubmed	The TIP60 Complex Is a Conserved Coactivator of HIF1A.	LRPPRC POLR2B RICTOR EFTUD2	7.30e-05	120	64	4	27320910
Pubmed	Crosstalk between Nodal/activin and MAPK p38 signaling is essential for anterior-posterior axis specification.	SUPT20HL1 SUPT20HL2	9.27e-05	8	64	2	21802298
Pubmed	PROTAC-mediated degradation reveals a non-catalytic function of AURORA-A kinase.	DHX36 MDN1 MIB1 BIRC6 CRBN	9.40e-05	247	64	5	32989298
Pubmed	C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.	DHX36 NCAPD3 LRPPRC MDN1 RARS1 POLR2B BIRC6 PCID2 NUP205 EFTUD2	9.42e-05	1257	64	10	37317656
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	LRPPRC MDN1 RARS1 PDCD6IP SYNE1 ISOC1 RICTOR EFTUD2	1.14e-04	807	64	8	30575818
Pubmed	SCFFbxo9 and CK2 direct the cellular response to growth factor withdrawal via Tel2/Tti1 degradation and promote survival in multiple myeloma.	TTI1 RICTOR	1.19e-04	9	64	2	23263282
Pubmed	CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.	DHX36 NCAPD3 LRPPRC MDN1 POLR2B TTI1 RICTOR	1.24e-04	606	64	7	36538041
Pubmed	Nuclear membrane proteins with potential disease links found by subtractive proteomics.	SYNE1 SYNE2	1.49e-04	10	64	2	12958361
Pubmed	Nesprin 1α2 is essential for mouse postnatal viability and nuclear positioning in skeletal muscle.	SYNE1 SYNE2	1.49e-04	10	64	2	28533284
Pubmed	Regulation of a distinct activated RIPK1 intermediate bridging complex I and complex II in TNFα-mediated apoptosis.	LRRK2 TNFAIP3	1.49e-04	10	64	2	29891719
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	PRAMEF33 PRAMEF10 PDCD6IP CTC1 POLR2B RICTOR TNFAIP3 EPDR1 LETM1	1.59e-04	1084	64	9	11544199
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	POLR2B HECTD4 EXOSC3 NVL RICTOR NUP205	1.60e-04	440	64	6	34244565
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	LRPPRC MDN1 RARS1 PDCD6IP POLR2B NUP205 EFTUD2	1.70e-04	638	64	7	33239621
Pubmed	Tti1 and Tel2 are critical factors in mammalian target of rapamycin complex assembly.	TTI1 RICTOR	1.81e-04	11	64	2	20427287
Pubmed	Glucagon regulates gluconeogenesis through KAT2B- and WDR5-mediated epigenetic effects.	SUPT20HL1 SUPT20HL2	1.81e-04	11	64	2	24051374
Pubmed	A conserved KASH domain protein associates with telomeres, SUN1, and dynactin during mammalian meiosis.	SYNE1 SYNE2	1.81e-04	11	64	2	22826121
Pubmed	Interactome Analysis of the Nucleocapsid Protein of SARS-CoV-2 Virus.	DHX36 NVL DHX57 LETM1	2.16e-04	159	64	4	34578187
Pubmed	Ubiquitin-specific peptidase 9, X-linked (USP9X) modulates activity of mammalian target of rapamycin (mTOR).	TTI1 RICTOR	2.17e-04	12	64	2	22544753
Pubmed	High-sensitivity profiling of SARS-CoV-2 noncoding region-host protein interactome reveals the potential regulatory role of negative-sense viral RNA.	DHX36 LRPPRC RARS1 POLR2B DHX57 EFTUD2	2.25e-04	469	64	6	37314180
Pubmed	KASH protein Syne-2/Nesprin-2 and SUN proteins SUN1/2 mediate nuclear migration during mammalian retinal development.	SYNE1 SYNE2	2.57e-04	13	64	2	21177258
Pubmed	The G4 resolvase RHAU regulates ventricular trabeculation and compaction through transcriptional and post-transcriptional mechanisms.	DHX36 MIB1	2.57e-04	13	64	2	34838591
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	LRPPRC MDN1 SYNE1 SYNE2 DHX57 PREX1 NIPBL LETM1 PCID2 NUP205	2.86e-04	1442	64	10	35575683
Pubmed	Craniofacial Defects in Embryos with Homozygous Deletion of Eftud2 in Their Neural Crest Cells Are Not Rescued by Trp53 Deletion.	CDC25B EFTUD2	2.99e-04	14	64	2	36012294
Pubmed	SUN1/2 and Syne/Nesprin-1/2 complexes connect centrosome to the nucleus during neurogenesis and neuronal migration in mice.	SYNE1 SYNE2	2.99e-04	14	64	2	19874786
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	NCAPD3 POLR2B APAF1 EXOSC3 BIRC6 NIPBL NUP205	3.09e-04	704	64	7	29955894
Pubmed	hLodestar/HuF2 interacts with CDC5L and is involved in pre-mRNA splicing.	PDCD6IP NVL	3.45e-04	15	64	2	12927788
Pubmed	Identification of potential protein interactors of Lrrk2.	MDN1 LRRK2	3.45e-04	15	64	2	17400507
Pubmed	Prohibitin 1 regulates tumor cell apoptosis via the interaction with X-linked inhibitor of apoptosis protein.	DHX36 LRPPRC MDN1 RARS1 POLR2B PREX1 EFTUD2	3.68e-04	725	64	7	27025967
Pubmed	Global Interactome Mapping of Mitochondrial Intermembrane Space Proteases Identifies a Novel Function for HTRA2.	LRPPRC MDN1 DHX57 RICTOR BIRC6 LETM1	3.71e-04	515	64	6	31617661
Pubmed	Transferrin Receptor Protein 1 Cooperates with mGluR2 To Mediate the Internalization of Rabies Virus and SARS-CoV-2.	LRPPRC MDN1 RARS1 EXOSC3 DHX57	3.75e-04	333	64	5	36779763
Pubmed	Multiple common variants for celiac disease influencing immune gene expression.	TNFAIP3 IL1RL2 FRMD4B	3.80e-04	76	64	3	20190752
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	DHX36 LRPPRC MDN1 SYNE1 POLR2B SYNE2 MIB1 DHX57 BIRC6 LETM1	3.83e-04	1496	64	10	32877691
Pubmed	RUFY1 binds Arl8b and mediates endosome-to-TGN CI-M6PR retrieval for cargo sorting to lysosomes.	LRPPRC RARS1 PDCD6IP NUP205 EFTUD2	4.35e-04	344	64	5	36282215
Pubmed	Framingham Heart Study 100K Project: genome-wide associations for blood pressure and arterial stiffness.	SYNE1 PREX1	4.45e-04	17	64	2	17903302
Interaction	PHLDA3 interactions	LRPPRC PDCD6IP NUP205 EFTUD2	2.10e-06	30	62	4	int:PHLDA3
Interaction	CIT interactions	DHX36 LRPPRC DNAH12 RARS1 SYNE1 POLR2B SYNE2 LRRK2 EXOSC3 NVL DHX57 BIRC6 NIPBL PCID2 NUP205 EFTUD2	5.46e-06	1450	62	16	int:CIT
Interaction	ANKRD55 interactions	NCAPD3 LRPPRC MDN1 RARS1 MIB1 NUP205 EFTUD2	6.27e-06	228	62	7	int:ANKRD55
Interaction	HECTD1 interactions	DHX36 NCAPD3 MDN1 IGHMBP2 POLR2B RPP38 EXOSC3 NVL DHX57 BIRC6 PCID2 NUP205 EFTUD2	7.41e-06	984	62	13	int:HECTD1
Interaction	IFI16 interactions	DHX36 PDCD6IP SYNE1 IGHMBP2 POLR2B EXOSC3 NVL DHX57 PCID2 NUP205 EFTUD2	1.00e-05	714	62	11	int:IFI16
Interaction	STK24 interactions	LRPPRC PDCD6IP LRRK2 ISOC1 RICTOR TNFAIP3	1.28e-05	168	62	6	int:STK24
Interaction	PEX3 interactions	VIPR1 LRPPRC MDN1 BIRC6 LETM1 NUP205	1.42e-05	171	62	6	int:PEX3
Interaction	RIT1 interactions	DHX36 NCAPD3 LRPPRC MDN1 RARS1 PDCD6IP TIPIN POLR2B LRRK2 NVL BIRC6 NIPBL NUP205 EFTUD2	1.70e-05	1230	62	14	int:RIT1
Interaction	RUVBL2 interactions	LRPPRC IGHMBP2 POLR2B LRRK2 TTI1 RICTOR STK40 NIPBL CRBN EFTUD2	1.70e-05	616	62	10	int:RUVBL2
Interaction	AKAP1 interactions	LRPPRC LRRC57 MDN1 POLR2B BIRC6 GPAT2 CEP43 LETM1 NUP205	2.19e-05	503	62	9	int:AKAP1
Interaction	CCDC8 interactions	LRPPRC DNAH12 MDN1 RARS1 PDCD6IP APAF1 TAP1 NIPBL NUP205 EFTUD2	2.91e-05	656	62	10	int:CCDC8
Interaction	YWHAZ interactions	NCAPD3 LRPPRC MAST4 FAM13A SYNE2 LRRK2 HECTD4 ISOC1 RICTOR TNFAIP3 CDC25B CRBN MAST3 EFTUD2	3.68e-05	1319	62	14	int:YWHAZ
Interaction	GSK3B interactions	DHX36 MAST4 RARS1 PDCD6IP LRRK2 RICTOR TNFAIP3 CEP43 CRBN NUP205 EFTUD2	6.03e-05	868	62	11	int:GSK3B
Interaction	RUVBL1 interactions	FAM20C LRPPRC IGHMBP2 POLR2B TTI1 RICTOR NIPBL CRBN EFTUD2	6.20e-05	575	62	9	int:RUVBL1
Interaction	CDC34 interactions	LRPPRC MDN1 PDCD6IP CTC1 POLR2B DHX57 NUP205	6.48e-05	328	62	7	int:CDC34
Interaction	PIH1D1 interactions	LRPPRC RARS1 PDCD6IP POLR2B ISOC1 TTI1 RICTOR BIRC6 CRBN EFTUD2	7.23e-05	731	62	10	int:PIH1D1
Interaction	SIRT7 interactions	DHX36 LRPPRC MDN1 PDCD6IP SYNE2 NVL DHX57 BIRC6 NIPBL NUP205	8.37e-05	744	62	10	int:SIRT7
Interaction	DDRGK1 interactions	NCAPD3 FAM20C LRPPRC MDN1 RARS1 IGHMBP2 RPP38 EXOSC3 NVL DHX57 PCID2 NUP205 EFTUD2	8.99e-05	1249	62	13	int:DDRGK1
Interaction	CIB2 interactions	CTC1 APAF1 RICTOR GPAT2	1.13e-04	81	62	4	int:CIB2
Interaction	PPP2CA interactions	NCAPD3 LRPPRC FAM13A POLR2B LRRK2 EXOSC3 CEP43 EFTUD2	1.13e-04	484	62	8	int:PPP2CA
Interaction	YWHAH interactions	MAST4 PDCD6IP FAM13A SYNE2 LRRK2 HECTD4 ISOC1 RICTOR TNFAIP3 CDC25B MAST3 EFTUD2	1.15e-04	1102	62	12	int:YWHAH
Cytoband	Xp22.11	SUPT20HL1 SUPT20HL2	3.95e-04	21	64	2	Xp22.11
GeneFamily	Spectrin repeat containing nuclear envelope family	SYNE1 SYNE2	2.71e-05	4	39	2	1252
GeneFamily	PDZ domain containing	MAST4 PREX1 MAST3 PDZRN4	3.14e-04	152	39	4	1220
GeneFamily	DEAH-box helicases	DHX36 DHX57	5.34e-04	16	39	2	500
GeneFamily	AAA ATPases	MDN1 NVL	5.83e-03	53	39	2	413
CoexpressionAtlas	dev gonad_e13.5_M_GermCell_Oct_k-means-cluster#1_top-relative-expression-ranked_1000	NCAPD3 LRPPRC MDN1 POLR2B NVL RICTOR CEP43 NUP205 EFTUD2	3.77e-07	333	60	9	gudmap_dev gonad_e13.5_M_GermCell_Oct_k1_1000
CoexpressionAtlas	dev gonad_e12.5_F_GermCellOvary_Oct_k-means-cluster#4_top-relative-expression-ranked_1000	TDRD5 NCAPD3 LRPPRC MDN1 RPP38 NVL CEP43 EFTUD2	4.02e-07	243	60	8	gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_k4_1000
CoexpressionAtlas	dev gonad_e13.5_M_GermCell_Oct_top-relative-expression-ranked_1000	TDRD5 NCAPD3 LRPPRC MDN1 CATSPER2 POLR2B RPP38 NVL RICTOR CEP43 NUP205 EFTUD2	2.27e-06	810	60	12	gudmap_dev gonad_e13.5_M_GermCell_Oct_1000
CoexpressionAtlas	dev gonad_e12.5_F_GermCellOvary_Oct_top-relative-expression-ranked_1000	TDRD5 AVEN NCAPD3 LRPPRC MDN1 CATSPER2 RPP38 NVL CEP43 NUP205 EFTUD2	1.65e-05	822	60	11	gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_2500_k-means-cluster#1	MAST4 PDCD6IP TIPIN SYNE2 EXOSC3 TTI1 DHX57 NIPBL CRBN LETM1	6.03e-05	780	60	10	Facebase_RNAseq_e10.5_Lateral Nasal Eminence_2500_K1
CoexpressionAtlas	dev gonad_e11.5_M_PrimGermCell_Oct_top-relative-expression-ranked_1000	TDRD5 AVEN NCAPD3 LRPPRC MDN1 RPP38 NVL CEP43 NUP205 EFTUD2	6.09e-05	781	60	10	gudmap_dev gonad_e11.5_M_PrimGermCell_Oct_1000
CoexpressionAtlas	dev gonad_e12.5_M_GermCellTestis_Oct_top-relative-expression-ranked_1000	TDRD5 AVEN NCAPD3 LRPPRC MDN1 RPP38 NVL CEP43 NUP205 EFTUD2	7.07e-05	795	60	10	gudmap_dev gonad_e12.5_M_GermCellTestis_Oct_1000
CoexpressionAtlas	dev gonad_e11.5_M_PrimGermCell_Oct_k-means-cluster#2_top-relative-expression-ranked_1000	AVEN NCAPD3 LRPPRC NVL NUP205 EFTUD2	8.77e-05	258	60	6	gudmap_dev gonad_e11.5_M_PrimGermCell_Oct_k2_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_2500_k-means-cluster#5	DHX36 PDCD6IP TIPIN SYNE2 EXOSC3 TTI1 DHX57 NIPBL CRBN LETM1	1.02e-04	831	60	10	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_2500_K5
CoexpressionAtlas	dev gonad_e12.5_M_GermCellTestis_Oct_k-means-cluster#2_top-relative-expression-ranked_1000	AVEN LRPPRC MDN1 NVL NUP205 EFTUD2	1.04e-04	266	60	6	gudmap_dev gonad_e12.5_M_GermCellTestis_Oct_k2_1000
CoexpressionAtlas	dev gonad_e12.5_M_GermCellTestis_Oct_k-means-cluster#4_top-relative-expression-ranked_500	TDRD5 LRPPRC MDN1 CEP43	1.64e-04	97	60	4	gudmap_dev gonad_e12.5_M_GermCellTestis_Oct_k4_500
CoexpressionAtlas	DevelopingGonad_e14.5_ ovary_emap-6699_k-means-cluster#1_top-relative-expression-ranked_500	MAST4 SYNE2 MIB1 FRMD4B	1.92e-04	101	60	4	gudmap_developingGonad_e14.5_ ovary_500_k1
CoexpressionAtlas	dev gonad_e11.5_F_PrimGermCell_Oct_k-means-cluster#3_top-relative-expression-ranked_1000	TDRD5 NCAPD3 LRPPRC MDN1 RPP38 NVL CEP43	3.19e-04	463	60	7	gudmap_dev gonad_e11.5_F_PrimGermCell_Oct_k3_1000
CoexpressionAtlas	DevelopingGonad_e16.5_ovary_emap-9563_top-relative-expression-ranked_1000	TDRD5 DHX36 MAST4 CATSPER2 SYNE2 BIRC6 GPAT2 FRMD4B CRBN	3.69e-04	795	60	9	gudmap_developingGonad_e16.5_ovary_1000
CoexpressionAtlas	DevelopingGonad_e12.5_ovary_emap-28876_top-relative-expression-ranked_1000	DHX36 MAST4 SYNE2 MIB1 RICTOR SPIDR BIRC6 GPAT2 FRMD4B	4.00e-04	804	60	9	gudmap_developingGonad_e12.5_ovary_1000
CoexpressionAtlas	DevelopingGonad_P2_ovary_emap-30224_k-means-cluster#4_top-relative-expression-ranked_200	TDRD5 GPAT2	4.25e-04	11	60	2	gudmap_developingGonad_P2_ovary_200_k4
CoexpressionAtlas	DevelopingGonad_e12.5_testes_emap-29069_top-relative-expression-ranked_1000	TDRD5 DHX36 MAST4 SYNE2 BIRC6 GPAT2 NIPBL FRMD4B PCID2	4.58e-04	819	60	9	gudmap_developingGonad_e12.5_testes_1000
CoexpressionAtlas	dev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_1000	TDRD5 AVEN NCAPD3 LRPPRC MDN1 CATSPER2 TIPIN NVL GPAT2	4.62e-04	820	60	9	gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_1000
CoexpressionAtlas	DevelopingGonad_e12.5_ovary_emap-28876_k-means-cluster#5_top-relative-expression-ranked_1000	SYNE2 MIB1 RICTOR SPIDR BIRC6	5.09e-04	233	60	5	gudmap_developingGonad_e12.5_ovary_k5_1000
CoexpressionAtlas	DevelopingGonad_P2_epididymis_emap-30199_k-means-cluster#3_top-relative-expression-ranked_1000	NCAPD3 MAST4 SYNE2 ISOC1 FRMD4B	6.88e-04	249	60	5	gudmap_developingGonad_P2_epididymis_1000_k3
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#4_top-relative-expression-ranked_100	MAST4 FRMD4B	6.99e-04	14	60	2	gudmap_developingGonad_e16.5_epididymis_100_k4
CoexpressionAtlas	DevelopingGonad_e14.5_ ovary_emap-6699_top-relative-expression-ranked_500	MAST4 SYNE2 MIB1 BIRC6 GPAT2 FRMD4B	7.19e-04	382	60	6	gudmap_developingGonad_e14.5_ ovary_500
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	FAM13A SYNE2 RICTOR TNFAIP3 BIRC6 NIPBL	3.01e-07	188	64	6	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l48\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IGHMBP2 DHX57 CDC25B CRBN NUP205	4.62e-06	170	64	5	070d8683d1a5cc7d594ff0453c961a9bf982c2d0
ToppCell	LPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MAST4 FAM13A SYNE2 LRRK2 CNIH3	5.94e-06	179	64	5	fd2cbee532e7b44113410dca82aec7db1a7fb69f
ToppCell	390C-Lymphocytic-CD4_T-cell-Treg_cell_3\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	VIPR1 MAST4 MIB1 LRRCC1 FRMD4B	7.16e-06	186	64	5	74eb69a52090f9e2426a47e03a1c478ee0cfec18
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_T-CytoT_GZMK+-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	SYNE1 SYNE2 CDC25B SPAG6 TAP1	8.35e-06	192	64	5	ed1fb700d3e8f00495727d61e164fc0b70274fd0
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_T-CytoT_GZMK+\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	SYNE1 SYNE2 CDC25B SPAG6 TAP1	8.35e-06	192	64	5	6779b0294bb058e748e22b795b6a381c4add37e9
ToppCell	(11)_FOXN4+-(2)_GFP_FOXI1\|(11)_FOXN4+ / shred by cell type by condition	SYNE2 RPP38 LRRCC1 TNFAIP3 NIPBL	9.69e-06	198	64	5	76d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCell	3'-Child09-12-SmallIntestine-Hematopoietic-B_cells-STAT1+_Naive_B\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TIPIN EFCAB13 CNIH3 PDZRN4	6.80e-05	152	64	4	dd728aa3ffdb2c415730a62678f69cf0e8af09df
ToppCell	10x5'-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8\|bone_marrow / Manually curated celltypes from each tissue	CTC1 SYNE2 RICTOR TNFAIP3	7.51e-05	156	64	4	1545169694f686d28648a68b552c2ae606599d66
ToppCell	droplet-Mammary_Gland-nan-21m-Epithelial-nan\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VIPR1 CTC1 LRRCC1 SPIDR	9.34e-05	165	64	4	7c771f22b58989572c939ed127e637ec28dc0dca
ToppCell	normal_Lung-Myeloid_cells-CD163+CD14+_DCs\|Myeloid_cells / Location, Cell class and cell subclass	APAF1 TNFAIP3 PREX1 FRMD4B	9.56e-05	166	64	4	07b498eb341abec02a3ccaae320bdbb5cd6883c5
ToppCell	390C-Epithelial_cells-Epithelial-I_(AT1)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	HENMT1 CATSPER2 TTI1 TNFAIP3	1.02e-04	169	64	4	6614c9851537e4c21b1e45ff0cc3bad07ef9d034
ToppCell	390C-Epithelial_cells-Epithelial-I_(AT1)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	HENMT1 CATSPER2 TTI1 TNFAIP3	1.02e-04	169	64	4	665b958f4a720ca369a8a0abc7fbe8b6e13c8ce5
ToppCell	10x_3'_v2v3-Non-neoplastic-Lymphoid-NK-NK-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HENMT1 TNFAIP3 GPAT2 PCID2	1.05e-04	170	64	4	aaf29c2d4de172d366cbfc863bc741941667dde1
ToppCell	CV-Mild-6\|Mild / Virus stimulation, Condition and Cluster	VIPR1 STK40 GPAT2 CNIH3	1.17e-04	175	64	4	c4d530dbb37942427c9cd0a1533faeb6a3a45381
ToppCell	BAL-Mild-cDC_4\|Mild / Compartment, Disease Groups and Clusters	IGHMBP2 SYNE2 LRRK2 RPP38	1.28e-04	179	64	4	68511e87b12b8253de7771e5ccfc5869248b8450
ToppCell	Control-Epithelial_cells-AT2\|Control / group, cell type (main and fine annotations)	MAST4 SYNE1 LRRK2 FRMD4B	1.31e-04	180	64	4	198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCell	390C-Lymphocytic-CD4_T-cell-Treg_cell_3\|390C / Donor, Lineage, Cell class and subclass (all cells)	VIPR1 MIB1 LRRCC1 FRMD4B	1.39e-04	183	64	4	228092290dbb08785c4eda224e3ad03e99e10fab
ToppCell	COVID-19-kidney-PCT-S1\|kidney / Disease (COVID-19 only), tissue and cell type	MAST4 SYNE2 LRRK2 FRMD4B	1.42e-04	184	64	4	51ed1ebfdef45149541917c66cbacad87072e51f
ToppCell	droplet-Lung-LUNG-30m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAM13A SLC38A5 EPDR1 FRMD4B	1.48e-04	186	64	4	ca5e9c6531cb5d199e27509bfab1d62e3937177e
ToppCell	droplet-Lung-LUNG-30m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAM13A SLC38A5 EPDR1 FRMD4B	1.48e-04	186	64	4	1ed71b229f40a680071b14f5a7a19706e0fd14b1
ToppCell	343B-Endothelial_cells-Endothelial-E\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	VIPR1 CDC25B TAP1 PREX1	1.48e-04	186	64	4	080e56113b89138277a2bd2eabddfa6cd1a18b61
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SYNE1 SYNE2 EFCAB13 LRRK2	1.48e-04	186	64	4	f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCell	343B-Endothelial_cells-Endothelial-E-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	VIPR1 CDC25B TAP1 PREX1	1.48e-04	186	64	4	dae6a98963c78bf7518ebab8dc02f173c3b0f7f7
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MAST4 FAM13A LRRK2 CNIH3	1.48e-04	186	64	4	e83718fabb057100835d3357df407f283d23fe16
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MAST4 SYNE2 STK40 FRMD4B	1.48e-04	186	64	4	b1edc341d6684b347dc9e21b34f62f51d095d735
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD4+_T-Treg-Treg_1\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	MAST4 SYNE2 CDC25B FRMD4B	1.51e-04	187	64	4	9fdfca5b70f585843ef9d810154674a8e561e765
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD4+_T-Treg-Treg_1\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MAST4 SYNE2 CDC25B FRMD4B	1.51e-04	187	64	4	a525753a8a908ee1ef0b8f06e68855e4af27bf86
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH12 CNIH2 SPAG6 CEP43	1.51e-04	187	64	4	7a50aded3243bef2075fb3ec550939ce0694919a
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH12 CNIH2 SPAG6 CEP43	1.51e-04	187	64	4	629b3e05840eb10e598b8dfaabd92ebe02f9995a
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH12 CNIH2 SPAG6 CEP43	1.51e-04	187	64	4	269145d71576cbe8fa217090c8aac82d915dbc04
ToppCell	VE-Treg\|VE / Condition, Cell_class and T cell subcluster	MAST4 FAM13A SYNE2 FRMD4B	1.54e-04	188	64	4	ef048517dfe2fc995d13eb1f08106a487354a4cc
ToppCell	VE-Treg-CD4_Treg\|VE / Condition, Cell_class and T cell subcluster	MAST4 FAM13A SYNE2 FRMD4B	1.54e-04	188	64	4	fa88ceb336e30de3585e62608527a0d44df74190
ToppCell	3'_v3-blood-Lymphocytic_T_CD8-Trm/em_CD8\|blood / Manually curated celltypes from each tissue	SYNE1 SYNE2 TNFAIP3 CDC25B	1.54e-04	188	64	4	21730497f95dc271e4cdfaaf1da8b9ac6eec2ded
ToppCell	droplet-Marrow-BM-30m-Hematologic-erythroblast\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCAPD3 SLC38A5 EPDR1 CDC25B	1.54e-04	188	64	4	f1a9d8ea174a4bef0fae8188e3bd96b7ac1a39bb
ToppCell	-Unknown-Endothelial-Myofibroblast\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RARS1 LRRK2 SPIDR EPDR1	1.54e-04	188	64	4	6468fa95ad0395395301115286f2d8c0df5d3882
ToppCell	-Unknown-Endothelial\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RARS1 LRRK2 SPIDR EPDR1	1.54e-04	188	64	4	7a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell	-Unknown\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RARS1 LRRK2 SPIDR EPDR1	1.54e-04	188	64	4	9cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCell	COPD-Multiplet-Multiplet\|World / Disease state, Lineage and Cell class	DNAH12 MAST4 SYNE1 SYNE2	1.54e-04	188	64	4	186fe1ea328c942910190a4240262c0d8642ea3b
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_T-CytoT_GZMK+-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	SYNE1 SYNE2 CDC25B TAP1	1.57e-04	189	64	4	f1129eb122bbc051457c5545f1a267beb988b0f2
ToppCell	HSPCs-Ery_prog.\|HSPCs / Lineage and Cell class	MAST4 SLC38A5 TNFAIP3 EPDR1	1.57e-04	189	64	4	37d2c45debed1564a40a1085b8b310c50923b9e7
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_T-CytoT_GZMK+\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	SYNE1 SYNE2 CDC25B TAP1	1.57e-04	189	64	4	0b012ee301419fa9ccc387c3ff66c2344b349a97
ToppCell	BAL-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MAST4 SYNE1 SYNE2 FRMD4B	1.61e-04	190	64	4	494fbab37305a7f92cddec75b291d42282555f5f
ToppCell	BAL-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MAST4 SYNE1 SYNE2 FRMD4B	1.61e-04	190	64	4	55df73c8b696967a925b1772631f6900eff0fa30
ToppCell	Non-neuronal-Postmitotic-Red_blood_cells-Low_Quality-14\|World / Primary Cells by Cluster	FAM13A SYNE2 HECTD4 PREX1	1.61e-04	190	64	4	feadd834d843f952aa7ced93899fd1f0868743df
ToppCell	Non-neuronal-Postmitotic-Red_blood_cells-Low_Quality\|World / Primary Cells by Cluster	FAM13A SYNE2 HECTD4 PREX1	1.61e-04	190	64	4	31cf1367db5c04242621f7c98a10d094bc519e31
ToppCell	Control-Endothelial-VE_Capillary_B\|Endothelial / Disease state, Lineage and Cell class	VIPR1 MAST4 SYNE1 PREX1	1.61e-04	190	64	4	7f3f419fffe02934b6f27b697f7a6401072491ed
ToppCell	Non-neuronal-Postmitotic-Red_blood_cells\|World / Primary Cells by Cluster	FAM13A SYNE2 HECTD4 PREX1	1.61e-04	190	64	4	f0b82334375749d917e440c493f10340c52ea13c
ToppCell	10x_3'_v3-lymph_node_(10x_3'_v3)-lymphocytic-T_lymphocytic-regulatory_T_cell\|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	MAST4 SYNE2 TNFAIP3 FRMD4B	1.61e-04	190	64	4	b69709323a9f1b368b5a4f87295b9f7fd9c9be8e
ToppCell	CTRL-Lymphoid-T_cell_&_NK_cell\|Lymphoid / Disease state, Lineage and Cell class	MAST4 SYNE2 TNFAIP3 FRMD4B	1.64e-04	191	64	4	32381d353e40bce77a5b63c7bdbe360d27327d86
ToppCell	mild_COVID-19-gd_T\|mild_COVID-19 / disease group, cell group and cell class (v2)	HENMT1 SYNE1 SYNE2 TNFAIP3	1.64e-04	191	64	4	0e43c097b92aaa831811d60e033262999e79dcd7
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_T-CytoT_GZMH+-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	SYNE1 SYNE2 CDC25B TAP1	1.71e-04	193	64	4	d66cbb8c71bdc57faecb74a16fe3f34cb0b33228
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MAST4 SYNE1 LRRK2 FRMD4B	1.71e-04	193	64	4	fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MAST4 SYNE1 LRRK2 FRMD4B	1.71e-04	193	64	4	f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_T-CytoT_GZMH+\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	SYNE1 SYNE2 CDC25B TAP1	1.71e-04	193	64	4	c1d9c2436503791350086a503d6b98c5c69f44ae
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD8+_T-CD8+_Tem\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	SYNE1 SYNE2 TNFAIP3 CDC25B	1.74e-04	194	64	4	ac03be73fdc32dacd4a450c0fb28617e043b8444
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TIPIN CNIH2 ISOC1 SLC38A5	1.74e-04	194	64	4	af4bbb2deb5a3913eb58990690fc3c62fbc3708c
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD8+_T-CD8+_Tem-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	SYNE1 SYNE2 TNFAIP3 CDC25B	1.74e-04	194	64	4	7ab4418a8a12c488d74af3676bdac672628da80c
ToppCell	390C-Epithelial_cells-Epithelial-I_(AT1)\|390C / Donor, Lineage, Cell class and subclass (all cells)	HENMT1 CATSPER2 NVL TTI1	1.74e-04	194	64	4	88db9f9e80c20ff3474f1f6459dcbdc25aec0b6d
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MAST4 SYNE1 LRRK2 FRMD4B	1.74e-04	194	64	4	97534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCell	390C-Epithelial_cells-Epithelial-I_(AT1)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	HENMT1 CATSPER2 NVL TTI1	1.74e-04	194	64	4	a71728202493d4858342ea2756ea281cd0d99a3a
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD8+_T-CD8+_Tem-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SYNE1 SYNE2 TNFAIP3 CDC25B	1.74e-04	194	64	4	760761ce7d22edf9a8cec71e8ab0caa273fce3f7
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD8+_T-CD8+_Tem\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SYNE1 SYNE2 TNFAIP3 CDC25B	1.74e-04	194	64	4	e72be6dc2711c1d4f16943c8615cf9dc2e961ff3
ToppCell	IPF-Multiplet-Multiplet\|IPF / Disease state, Lineage and Cell class	DNAH12 MAST4 SYNE1 SYNE2	1.77e-04	195	64	4	fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCell	IPF-Multiplet\|IPF / Disease state, Lineage and Cell class	DNAH12 MAST4 SYNE1 SYNE2	1.77e-04	195	64	4	eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCell	Healthy-CD8+_Tem\|World / disease group, cell group and cell class	SYNE1 SYNE2 TNFAIP3 CDC25B	1.77e-04	195	64	4	3d6f46b31c0254e9577a560364694b42964df198
ToppCell	IPF-Multiplet-Multiplet\|World / Disease state, Lineage and Cell class	DNAH12 MAST4 SYNE2 SPAG6	1.77e-04	195	64	4	21dbdc803c6947024dc2416e9e21c2ef0af9bc31
ToppCell	Healthy-CD4+_CTL\|World / disease group, cell group and cell class	SYNE1 SYNE2 TNFAIP3 CDC25B	1.81e-04	196	64	4	6a623eeb2ba8d4e16543820bcbba41eecbd00ed2
ToppCell	10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-Stress_sig-F_2\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SYNE1 SYNE2 TNFAIP3 TAP1	1.81e-04	196	64	4	ea8eceacc5d5e1a22b77c31e7c45985dc7bb15de
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	FAM13A SYNE1 SYNE2 TNFAIP3	1.81e-04	196	64	4	e4c76e7ad68455e51fe93ce588bcec9383f8654b
ToppCell	healthy_donor-Lymphocytic-T_cell-CD8+_Memory_T_cell\|healthy_donor / Disease condition, Lineage, Cell class and subclass	SYNE1 SYNE2 TNFAIP3 CDC25B	1.81e-04	196	64	4	af00c31612e4fe068e5fccae05368edba46bbd20
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-IPC/newborn-38\|World / Primary Cells by Cluster	SYNE2 HECTD4 PREX1 FRMD4B	1.81e-04	196	64	4	38da0751941adca650fe9b383d9f343153978eb5
ToppCell	COPD-Multiplet\|COPD / Disease state, Lineage and Cell class	DNAH12 MAST4 SYNE1 SYNE2	1.81e-04	196	64	4	6d02d494196e3f857d53eea46d9419690d43beca
ToppCell	COPD-Multiplet-Multiplet\|COPD / Disease state, Lineage and Cell class	DNAH12 MAST4 SYNE1 SYNE2	1.81e-04	196	64	4	af4cdc61830685a888a1209826c23bcf54a43084
ToppCell	severe_COVID-19-CD8+_Tem\|World / disease group, cell group and cell class (v2)	SYNE1 SYNE2 TNFAIP3 CDC25B	1.81e-04	196	64	4	f0d3067b0f596dd84da2af4bf062fb9f04ef1dc4
ToppCell	COVID-19-lung-Capillary_Aerocytes\|COVID-19 / Disease (COVID-19 only), tissue and cell type	VIPR1 SYNE1 SYNE2 PREX1	1.81e-04	196	64	4	49cc0a2b9739abad61dff7292ea0b14d28ff35c4
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-IPC/newborn\|World / Primary Cells by Cluster	SYNE2 HECTD4 PREX1 FRMD4B	1.81e-04	196	64	4	721650a08d260faf530dbd52d4e9275d27f3bac2
ToppCell	LPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_only / Treatment groups by lineage, cell group, cell type	FAM13A SYNE2 LRRK2 CNIH3	1.84e-04	197	64	4	1a1bee8da6e04b65935c40373eaee4d6c046d9a1
ToppCell	erythropoietic\|World / Lineage and Cell class	FAM13A LRRCC1 SLC38A5 EPDR1	1.84e-04	197	64	4	a52546cebc222050c970e04cec97e4f48ab8fe10
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-Teffector/EM_CD4\|lymph-node_spleen / Manually curated celltypes from each tissue	VIPR1 SYNE2 TNFAIP3 CDC25B	1.84e-04	197	64	4	c4603bfe9ab537ca64172f65203a5d23671f7354
ToppCell	erythropoietic-Polychromatic_Erythroblast\|World / Lineage and Cell class	FAM13A LRRCC1 SLC38A5 EPDR1	1.84e-04	197	64	4	604fcbf47f073c2af344e1b16b615a78ef838dc9
ToppCell	10x5'-Liver-Lymphocytic_T_CD4\|Liver / Manually curated celltypes from each tissue	MAST4 SYNE2 TNFAIP3 FRMD4B	1.84e-04	197	64	4	4891111894b741555f549deec6af8006376d9358
ToppCell	10x5'-Liver-Lymphocytic_T_CD8-Tem/emra_CD8\|Liver / Manually curated celltypes from each tissue	SYNE1 SYNE2 TNFAIP3 CDC25B	1.88e-04	198	64	4	2fc2a4638c458ae793ac090a29d27b75fc9e6af6
ToppCell	Control-PLT_4\|Control / Disease Group and Platelet Clusters	DHX36 DNAH12 FRMD4B CRBN	1.88e-04	198	64	4	387fd3037fd52e4d4c42de0588767e58af228b59
ToppCell	COVID-19-lung-Capillary_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	VIPR1 MIB1 CDC25B PREX1	1.88e-04	198	64	4	45419f2804b4be79bae6632e71c54e1af482d115
ToppCell	systemic_lupus_erythematosus-flare\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	SYNE1 SYNE2 RICTOR TAP1	1.88e-04	198	64	4	4c93ee921d56132d80832d8e94563f32ccf13bbc
ToppCell	severe-Treg\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	MAST4 SYNE2 CDC25B FRMD4B	1.88e-04	198	64	4	377980b9f7d02818e1d145e6884604f8bfacc4f2
ToppCell	severe_COVID-19-CD8+_Tem\|severe_COVID-19 / disease group, cell group and cell class (v2)	SYNE1 SYNE2 TNFAIP3 CDC25B	1.88e-04	198	64	4	69d49f37cf5095e65c71cddc6d43748322ff19a3
ToppCell	PBMC-Mild-Lymphocyte-T/NK\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SYNE1 SYNE2 TNFAIP3 CDC25B	1.92e-04	199	64	4	dfdf551a292e33e3ee356629fa48a0a2f009624d
ToppCell	PBMC-Mild-Lymphocyte-T/NK\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	SYNE1 SYNE2 TNFAIP3 CDC25B	1.92e-04	199	64	4	ec7a1b0b71175b3a4015522bf88784eb176d59e3
ToppCell	Hematolymphoid-Endothelial-NOSTRIN\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	MAST4 SYNE1 SYNE2 SLC38A5	1.95e-04	200	64	4	032df80aa5c40991e1c1e80f9d8da106e6aeaee2
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	MAST4 SYNE2 BIRC6 NIPBL	1.95e-04	200	64	4	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	COVID-19_Mild-Lymphoid_T/NK\|COVID-19_Mild / Disease group, lineage and cell class	SYNE1 SYNE2 TNFAIP3 CDC25B	1.95e-04	200	64	4	e69416952039ca076e9b71187d8783fe567ee873
ToppCell	Hematolymphoid-Endothelial-NOSTRIN--\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	MAST4 SYNE1 SYNE2 SLC38A5	1.95e-04	200	64	4	7fa54370221ed61bac0e09e6bcf1f3dff202a846
ToppCell	Hematolymphoid-Endothelial-NOSTRIN---\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	MAST4 SYNE1 SYNE2 SLC38A5	1.95e-04	200	64	4	68fce28690246895fd33354b30960ebcc31aa4cc
ToppCell	Control-Control-Lymphocyte-T/NK-CD8+_Tem\|Control / Disease, condition lineage and cell class	SYNE1 SYNE2 TNFAIP3 CDC25B	1.95e-04	200	64	4	fddb3df5b90eb97ef8ed80fac320c1a90903f012
ToppCell	Hematolymphoid-Endothelial-NOSTRIN-\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	MAST4 SYNE1 SYNE2 SLC38A5	1.95e-04	200	64	4	376b19ab5a7cd2c85f726d8ba41337d4525863e5
ToppCell	Hematolymphoid-Endothelial-NOSTRIN----L2-6\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	MAST4 SYNE1 SYNE2 SLC38A5	1.95e-04	200	64	4	878bbbe32e3602723aa14ef32877ab2453b8c6e5
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK\|COVID-19_Mild / Disease, condition lineage and cell class	SYNE1 SYNE2 TNFAIP3 CDC25B	1.95e-04	200	64	4	6d9796153d038329a820949c0b88fd01265a1227
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SYNE2 TNFAIP3 BIRC6 NIPBL	1.95e-04	200	64	4	12f1685ce8f218433068e090c9d839cd5a1910bf
Disease	Autosomal dominant Emery-Dreifuss muscular dystrophy	SYNE1 SYNE2	2.52e-05	4	61	2	cv:CN293514
Disease	Autosomal Recessive Emery-Dreifuss Muscular Dystrophy	SYNE1 SYNE2	4.19e-05	5	61	2	C1450051
Disease	Autosomal Dominant Emery-Dreifuss Muscular Dystrophy (disorder)	SYNE1 SYNE2	4.19e-05	5	61	2	C0410190
Disease	Emery-Dreifuss muscular dystrophy	SYNE1 SYNE2	6.27e-05	6	61	2	cv:C0410189
Disease	Muscular Dystrophy, Emery-Dreifuss	SYNE1 SYNE2	6.27e-05	6	61	2	C0410189
Disease	X-Linked Emery-Dreifuss Muscular Dystrophy	SYNE1 SYNE2	8.77e-05	7	61	2	C0751337
Disease	Emery-Dreifuss muscular dystrophy (implicated_via_orthology)	SYNE1 SYNE2	2.74e-04	12	61	2	DOID:11726 (implicated_via_orthology)
Disease	forced expiratory volume, response to bronchodilator	MAST4 FAM13A SYNE1 RICTOR PREX1 NUP205	3.13e-04	445	61	6	EFO_0004314, GO_0097366
Disease	esophagus squamous cell carcinoma (is_marker_for)	RICTOR TNFAIP3 TAP1	4.91e-04	74	61	3	DOID:3748 (is_marker_for)
Disease	primary autosomal recessive microcephaly (is_implicated_in)	NCAPD3 PDCD6IP	4.95e-04	16	61	2	DOID:0070296 (is_implicated_in)
Disease	blood pressure	SYNE1 PREX1	9.46e-04	22	61	2	EFO_0004325
Disease	malaria	AVEN TNFAIP3 CRBN	1.25e-03	102	61	3	EFO_0001068

Protein segments in the cluster

Peptide	Gene	Start	Entry
LKDCRIQDPQLRVLL	PRAMEF33	356	A0A0G2JMD5
RIQECLRKEIRSLLI	TDRD5	6	Q8NAT2
LPLNIEEAKDRLRIL	APAF1	216	O14727
VRVLDERKALIPCKR	EPDR1	76	Q9UM22
LCEIVNEPQLERLLL	BIRC6	2371	Q9NR09
LQLLRICRVLRSLKL	CATSPER2	206	Q96P56
RLLLLKPECVQELEL	CTC1	306	Q2NKJ3
ACLPIDDVLRIQLLK	CRBN	286	Q96SW2
CKRIVLLVARPEIQL	PDZRN4	476	Q6ZMN7
ERILQTLCRKLRLPQ	NVL	441	O15381
LLRESQLALIVCPLE	NUP205	866	Q92621
PRLKILRLEENCLEL	LRRC57	176	Q8N9N7
ERCKVRLVPLQIQLT	ISOC1	91	Q96CN7
APLSQRLCEELRLIL	MDN1	5321	Q9NU22
LTRPQLVALCKLLEL	LETM1	321	O95202
LIKELPELLQRNREI	PDCD6IP	436	Q8WUM4
KRVIKILRDICIEQP	NIPBL	1866	Q6KC79
QKIIILRCLRPDKIT	DNAH12	2446	Q6ZR08
ELVCLTRRILLPKNV	LRRK2	2136	Q5S007
CSVIRPILKRLERPQ	CDC25B	326	P30305
QPIRDVLKQLILVLC	LRPPRC	676	P42704
PKLVLIILQLCRAAL	HECTD4	1421	Q9Y4D8
LRCENLARLIIVKEV	FAM13A	241	O94988
PMCRILLRKEVLRLV	RICTOR	1606	Q6R327
ECPICRKAIERRILL	MIB1	991	Q86YT6
NVKLCRRLIVIVVPE	IL1RL2	441	Q9HB29
IRCGIFLILEKLKII	PCID2	306	Q5JVF3
LDDRRLELLVQPKLL	FRMD4B	66	Q9Y2L6
LLRLLKVNPCIELLV	HENMT1	61	Q5T8I9
PLLLEVIRRCQQKEK	CEP43	126	O95684
ELLVRALQELPLCLR	AVEN	181	Q9NQS1
LSILVPLQQCCRIRK	FAM20C	491	Q8IXL6
ILRTPLEELCLQIKI	DHX36	631	Q9H2U1
RVPLEQLCLRIKILE	DHX57	996	Q6P158
PLLALKEEDQLLVRR	GPAT2	431	Q6NUI2
VNDLPVILCILRISI	EFCAB13	191	Q8IY85
KLLIIISRPARLLEC	MAST3	271	O60307
KILIVIARPARLLEC	MAST4	471	O15021
LLRPEQVLKRLAVCV	EME2	66	A4GXA9
LIRKLLAPDCEIIQE	EXOSC3	206	Q9NQT5
RCILRFPEILQKILD	RARS1	576	P54136
LLVLCIQEPEIALKR	SPAG6	171	O75602
ENTVCLIRKLLVLDP	STK40	301	Q8N2I9
EKLVRRESLPCLLVN	SUPT20HL1	66	Q3ZLR7
RRELLLVLVCKSVKP	RPP38	126	P78345
KRLQLIEELCVKLPV	SYNE1	1076	Q8NF91
LRLVLPVEKASLLLC	SYNE2	1221	Q8WXH0
KDPLILCVRLAVLLA	SLC38A5	331	Q8WUX1
QLIRPINALDELCRL	PREX1	1531	Q8TCU6
ICRPLLIVEKQKLLL	POLR2B	621	P30876
VALARALIRKPCVLI	TAP1	651	Q03518
EKLVRRESLPCLLVN	SUPT20HL2	66	P0C7V6
LCPARVEKRIFLLIQ	NCAPD3	866	P42695
NIERICCLLRKLVVP	CNIH2	56	Q6PI25
NIERICFLLRKLVLP	CNIH3	56	Q8TBE1
LFICIIRILLQKLRP	VIPR1	311	P32241
IFVLCNILRRPIIVI	TNFAIP3	196	P21580
RIVCAERTVLLLQKP	SPIDR	731	Q14159
LVERLALCKQRILRL	IGHMBP2	251	P38935
LKDCRIQDPQLRVLL	PRAMEF10	356	O60809
AVILLLRQVQCKPLL	TTC37	1361	Q6PGP7
EELKLNIRPLLRLVC	EFTUD2	406	Q15029
VQTCLKRIRLDLPIL	TIPIN	136	Q9BVW5
IRLKVLDVLDLCVVV	TTI1	881	O43156
VILQTLPQLRILDCK	LRRCC1	186	Q9C099