Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionphosphoribosylamine-glycine ligase activity

GART IFNAR1

2.95e-0521092GO:0004637
GeneOntologyMolecularFunctiontryptophan 5-monooxygenase activity

TPH2 TPH1

2.95e-0521092GO:0004510
GeneOntologyMolecularFunctionryanodine-sensitive calcium-release channel activity

RYR2 RYR3

1.76e-0441092GO:0005219
GeneOntologyMolecularFunctioncalcium-induced calcium release activity

RYR2 RYR3

4.37e-0461092GO:0048763
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen

TPH2 TPH1

6.09e-0471092GO:0016714
GeneOntologyCellularComponentfilopodium membrane

NF2 SYNE2 NINJ1

1.58e-04211063GO:0031527
GeneOntologyCellularComponentendosome

FKBP15 FLOT2 WASHC2C RIPK1 TRIO ZFYVE16 SPTBN2 UBR4 VPS8 AP3B1 IFNAR1 NF2 ABCA5 TRAPPC6B ATP11C RAP2C

2.57e-04116710616GO:0005768
DomainTrp_5_mOase

TPH2 TPH1

3.25e-0521072IPR005963
DomainACT_dom

TPH2 TPH1

9.72e-0531072IPR002912
DomainRyanodine_rcpt

RYR2 RYR3

9.72e-0531072IPR003032
DomainACT

TPH2 TPH1

9.72e-0531072PS51671
DomainACT

TPH2 TPH1

9.72e-0531072PF01842
DomainRyanrecept_TM4-6

RYR2 RYR3

9.72e-0531072IPR009460
DomainRyR

RYR2 RYR3

9.72e-0531072PF02026
DomainRR_TM4-6

RYR2 RYR3

9.72e-0531072PF06459
DomainRyan_recept

RYR2 RYR3

9.72e-0531072IPR013333
Domain-

GTF2IRD2B GTF2IRD2

1.94e-04410723.90.1460.10
Domain-

TPH2 TPH1

1.94e-04410721.10.800.10
DomainArAA_hydroxylase_Fe/CU_BS

TPH2 TPH1

1.94e-0441072IPR018301
DomainBH4_AAA_HYDROXYL_2

TPH2 TPH1

1.94e-0441072PS51410
DomainArAA_hydroxylase

TPH2 TPH1

1.94e-0441072IPR001273
DomainBiopterin_H

TPH2 TPH1

1.94e-0441072PF00351
DomainGTF2I

GTF2IRD2B GTF2IRD2

1.94e-0441072PS51139
DomainGTF2I

GTF2IRD2B GTF2IRD2

1.94e-0441072PF02946
DomainTyrosine_3-monooxygenase-like

TPH2 TPH1

1.94e-0441072IPR019773
DomainAromatic-AA_hydroxylase_C

TPH2 TPH1

1.94e-0441072IPR019774
DomainGTF2I

GTF2IRD2B GTF2IRD2

1.94e-0441072IPR004212
DomainBH4_AAA_HYDROXYL_1

TPH2 TPH1

1.94e-0441072PS00367
DomainSpectrin

TRIO SPTBN2 SYNE2

2.98e-04231073PF00435
DomainRIH_assoc-dom

RYR2 RYR3

4.80e-0461072IPR013662
DomainIns145_P3_rec

RYR2 RYR3

4.80e-0461072PF08709
DomainRIH_assoc

RYR2 RYR3

4.80e-0461072PF08454
DomainRIH_dom

RYR2 RYR3

4.80e-0461072IPR000699
DomainIns145_P3_rcpt

RYR2 RYR3

4.80e-0461072IPR014821
DomainRyanodine_recept-rel

RYR2 RYR3

4.80e-0461072IPR015925
Domain-

RYR2 RYR3

4.80e-04610721.25.10.30
DomainRYDR_ITPR

RYR2 RYR3

4.80e-0461072PF01365
DomainSpectrin_repeat

TRIO SPTBN2 SYNE2

5.99e-04291073IPR002017
DomainSPEC

TRIO SPTBN2 SYNE2

8.03e-04321073SM00150
DomainSpectrin/alpha-actinin

TRIO SPTBN2 SYNE2

8.03e-04321073IPR018159
DomainMIR

RYR2 RYR3

1.42e-03101072PF02815
DomainMIR_motif

RYR2 RYR3

1.42e-03101072IPR016093
DomainMIR

RYR2 RYR3

1.42e-03101072PS50919
DomainMIR

RYR2 RYR3

1.42e-03101072SM00472
DomainWW

CEP164 YAP1 WBP4

2.62e-03481073SM00456
DomainATP_GRASP

GART SUCLG2

2.83e-03141072PS50975
DomainATP-grasp

GART SUCLG2

2.83e-03141072IPR011761
DomainWW_DOMAIN_1

CEP164 YAP1 WBP4

3.12e-03511073PS01159
DomainWW_DOMAIN_2

CEP164 YAP1 WBP4

3.12e-03511073PS50020
DomainOAR

SHOX SHOX2

3.25e-03151072PF03826
Domain-

GART SUCLG2

3.25e-031510723.30.1490.20
DomainWW_dom

CEP164 YAP1 WBP4

3.30e-03521073IPR001202
DomainARM-type_fold

UBR4 CLASP2 AP3B1 RYR3 PPP2R5A UNC79 FMNL1

3.38e-033391077IPR016024
DomainOAR

SHOX SHOX2

3.70e-03161072PS50803
DomainOAR_dom

SHOX SHOX2

3.70e-03161072IPR003654
DomainATP_grasp_subdomain_1

GART SUCLG2

4.69e-03181072IPR013815
Domain-

GART SUCLG2

4.69e-031810723.30.470.20
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

NUDT19 FLOT2 CCPG1 MIA3 UGGT1 SPTBN2 UBR4 CLASP2 CEP192 AP3B1 DICER1 WDR3 GUF1 AKAP9 NF2 SYNE2 PEX19 DHX29 XRCC6 GOLGB1

4.09e-0814871102033957083
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

FKBP15 MIA3 CEP162 PPP1R13B CLASP2 CEP192 AKAP9 NF2 YAP1 MTCL1 FMNL1

1.86e-074461101124255178
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

FKBP15 MIA3 TRIO SPTBN2 UBR4 EFHD2 CLASP2 AKAP9 SYNE2 SMARCC2 MTCL1 TACC3 UNC79 XRCC6 GOLGB1

3.93e-079631101528671696
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

FKBP15 FLOT2 ZNF536 MIA3 TRIO ZFYVE16 UGGT1 EFHD2 CLASP2 DICER1 YAP1 WBP4 PEX19

5.92e-077331101334672954
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

BICD2 WASHC2C WEE1 RBBP6 SIN3A SNX33 INTS3 IFI16 YAP1 SMARCC2 TACC3 DHX29 XRCC6

1.09e-067741101315302935
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

MIA3 TRIO ZFYVE16 CEP162 UGGT1 SPTBN2 PPP1R13B CLASP2 CEP192 AP3B1 PPP2R5A AKAP9 NF2 SYNE2 PEX19

1.14e-0610491101527880917
Pubmed

Expression of testicular germ cell genes identified by differential display analysis.

ANKRD20A3P ANKRD20A8P ANKRD20A4P

1.70e-068110312634303
Pubmed

Functional proteomics mapping of a human signaling pathway.

ZFYVE16 RBBP6 UBR4 VPS8 PPP1R13B SVEP1 RYR2 PEX19 FMNL1 XRCC6 GOLGB1

2.91e-065911101115231748
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

BICD2 FLOT2 MIA3 WASHC2C TRIO CEP162 GPATCH1 SPTBN2 PPP1R13B EFHD2 CEP192 CEP164 WDR3

3.15e-068531101328718761
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

MIA3 TRIO CLASP2 CEP192 DICER1 HELB MTCL1

4.82e-06209110736779422
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

FLOT2 ZNF536 WEE1 UBR4 AP3B1 INTS3 RYR2 SYNE2 WBP4 SMARCC2 MTCL1

6.00e-066381101131182584
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

BICD2 FKBP15 ZNF536 WASHC2C ZFYVE16 VPS8 CEP192 AKAP9 MTCL1

6.18e-06407110912693553
Pubmed

Cep120 and TACCs control interkinetic nuclear migration and the neural progenitor pool.

CEP162 CEP164 TACC3

8.60e-0613110317920017
Pubmed

Transforming acidic coiled-coil-containing protein 4 interacts with centrosomal AKAP350 and the mitotic spindle apparatus.

AKAP9 TACC3

9.91e-062110212015314
Pubmed

Attention-deficit/hyperactivity disorder symptoms in offspring of mothers with impaired serotonin production.

TPH2 TPH1

9.91e-062110220921119
Pubmed

Association of functional polymorphisms of the human tryptophan hydroxylase 2 gene with risk for bipolar disorder in Han Chinese.

TPH2 TPH1

9.91e-062110217768266
Pubmed

Common variants in the TPH1 and TPH2 regions are not associated with persistent ADHD in a combined sample of 1,636 adult cases and 1,923 controls from four European populations.

TPH2 TPH1

9.91e-062110220213726
Pubmed

Predominant expression of tryptophan hydroxylase 1 mRNA in the pituitary: a postmortem study in human brain.

TPH2 TPH1

9.91e-062110219233335
Pubmed

Family-based association study of TPH1 and TPH2 polymorphisms in autism.

TPH2 TPH1

9.91e-062110216958027
Pubmed

The role of the TPH1 and TPH2 genes for nicotine dependence: a genetic association study in two different age cohorts.

TPH2 TPH1

9.91e-062110217986837
Pubmed

Tissue-specific alternative splicing of mouse brain type ryanodine receptor/calcium release channel mRNA.

RYR2 RYR3

9.91e-06211028898078
Pubmed

Synthesis of serotonin by a second tryptophan hydroxylase isoform.

TPH2 TPH1

9.91e-062110212511643
Pubmed

The mouse sino-atrial node expresses both the type 2 and type 3 Ca(2+) release channels/ryanodine receptors.

RYR2 RYR3

9.91e-062110214550562
Pubmed

Merlin controls the repair capacity of Schwann cells after injury by regulating Hippo/YAP activity.

NF2 YAP1

9.91e-062110228137778
Pubmed

Genetic disruption of both tryptophan hydroxylase genes dramatically reduces serotonin and affects behavior in models sensitive to antidepressants.

TPH2 TPH1

9.91e-062110218923670
Pubmed

Expression, purification and enzymatic characterization of the catalytic domains of human tryptophan hydroxylase isoforms.

TPH2 TPH1

9.91e-062110219816759
Pubmed

Expressing human SHOX in Shox2SHOX KI/KI mice leads to congenital osteoarthritis‑like disease of the temporomandibular joint in postnatal mice.

SHOX SHOX2

9.91e-062110227601064
Pubmed

Common genetic variations in TPH1/TPH2 genes are not associated with schizophrenia in Japanese population.

TPH2 TPH1

9.91e-062110220144688
Pubmed

A unique central tryptophan hydroxylase isoform.

TPH2 TPH1

9.91e-062110214563478
Pubmed

Human placenta expresses both peripheral and neuronal isoform of tryptophan hydroxylase.

TPH2 TPH1

9.91e-062110228751217
Pubmed

Intercellular interaction dictates cancer cell ferroptosis via NF2-YAP signalling.

NF2 YAP1

9.91e-062110231341276
Pubmed

Maternal serotonin is crucial for murine embryonic development.

TPH2 TPH1

9.91e-062110217182745
Pubmed

Association between single nucleotide polymorphisms of TPH1 and TPH2 genes, and depressive disorders.

TPH2 TPH1

9.91e-062110229314569
Pubmed

Altered ryanodine receptor expression in mild cognitive impairment and Alzheimer's disease.

RYR2 RYR3

9.91e-062110221531043
Pubmed

Modulation of calcium signalling by dominant negative splice variant of ryanodine receptor subtype 3 in native smooth muscle cells.

RYR2 RYR3

9.91e-062110216678258
Pubmed

TPH2 and TPH1: association of variants and interactions with heroin addiction.

TPH2 TPH1

9.91e-062110218181017
Pubmed

Interaction of FAM5C with UDP-glucose:glycoprotein glucosyltransferase 1 (UGGT1): Implication of N-glycosylation in FAM5C secretion.

BRINP3 UGGT1

9.91e-062110228351617
Pubmed

Comparative transgenic analysis of enhancers from the human SHOX and mouse Shox2 genomic regions.

SHOX SHOX2

9.91e-062110223575226
Pubmed

Association of TPH-1 and TPH-2 gene polymorphisms with suicidal behavior: a systematic review and meta-analysis.

TPH2 TPH1

9.91e-062110225005534
Pubmed

Differential tissue distribution of tryptophan hydroxylase isoforms 1 and 2 as revealed with monospecific antibodies.

TPH2 TPH1

9.91e-062110216581041
Pubmed

Associations of tryptophan hydroxylase gene polymorphisms with irritable bowel syndrome.

TPH2 TPH1

9.91e-062110221073637
Pubmed

Acyl-CoA thioesterase 12 suppresses YAP-mediated hepatocarcinogenesis by limiting glycerolipid biosynthesis.

ACOT12 YAP1

9.91e-062110237150501
Pubmed

NF2 Activates Hippo Signaling and Promotes Ischemia/Reperfusion Injury in the Heart.

NF2 YAP1

9.91e-062110227402866
Pubmed

Disruption of the nonneuronal tph1 gene demonstrates the importance of peripheral serotonin in cardiac function.

TPH2 TPH1

9.91e-062110214597720
Pubmed

Spatio-temporal expression of tryptophan hydroxylase isoforms in murine and human brain: convergent data from Tph2 knockout mice.

TPH2 TPH1

9.91e-062110219181488
Pubmed

The neurofibromatosis 2 tumor suppressor gene product, merlin, regulates human meningioma cell growth by signaling through YAP.

NF2 YAP1

9.91e-062110218953429
Pubmed

Genetic, Psychological, and Personal Network Factors Associated With Changes in Binge Drinking Over 2 Years Among Mexican Heritage Adolescents in the USA.

TPH2 TPH1

9.91e-062110229697747
Pubmed

Isoform-Specific Substrate Inhibition Mechanism of Human Tryptophan Hydroxylase.

TPH2 TPH1

9.91e-062110229035515
Pubmed

The tryptophan hydroxylase gene influences risk for bipolar disorder but not major depressive disorder: results of meta-analyses.

TPH2 TPH1

9.91e-062110219032713
Pubmed

Comparison of TFII-I gene family members deleted in Williams-Beuren syndrome.

GTF2IRD2B GTF2IRD2

9.91e-062110215388857
Pubmed

Decreased expression of ryanodine receptors alters calcium-induced calcium release mechanism in mdx duodenal myocytes.

RYR2 RYR3

9.91e-062110214985349
Pubmed

YAP1 is involved in mesothelioma development and negatively regulated by Merlin through phosphorylation.

NF2 YAP1

9.91e-062110218725387
Pubmed

Tagging genes with cassette-exchange sites.

UGGT1 UBR4 CLASP2 AP3B1 YAP1 PEX19 DHX29 XRCC6

1.19e-05335110815741177
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

NUDT19 FLOT2 COG7 UGGT1 SPTBN2 UBR4 VPS8 SUCLG2 IFI16 DICER1 WDR3 TRAPPC6B SYNE2 PEX19 DHX29 XRCC6

1.22e-0514401101630833792
Pubmed

Proximity labelling identifies pro-migratory endocytic recycling cargo and machinery of the Rab4 and Rab11 families.

BICD2 FLOT2 ZFYVE16 VPS8 CLIC4 EFHD2 FMNL1 GOLGB1

1.30e-05339110837232246
Pubmed

Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?

FLOT2 UBR4 CEP192 CEP164 SYNE2 UNC79

1.76e-05170110623314748
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

FLOT2 TRIO WEE1 CEP162 CLASP2 CEP192 DENND1B AKAP9 YAP1 SYNE2 MTCL1 GOLGB1

1.88e-058611101236931259
Pubmed

Mapping HSA 3 loci in cattle: additional support for the ancestral synteny of HSA 3 and 21.

COL6A2 GART IFNAR1

2.43e-051811031783381
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

UGGT1 UBR4 GART CLIC4 EFHD2 HMGCS1 SIN3A SUCLG2 INTS3 SYNE2 PARP9 TACC3 DHX29 XRCC6 GOLGB1

2.71e-0513671101532687490
Pubmed

Comparative gene mapping of human chromosome 21 and mouse chromosome 16.

GART IFNAR1

2.97e-05311023160288
Pubmed

Type 1 and type 3 ryanodine receptors are selectively involved in muscarinic antinociception in mice: an antisense study.

RYR2 RYR3

2.97e-053110218403125
Pubmed

Transient expression of secretin in serotoninergic neurons of mouse brain during development.

TPH2 TPH1

2.97e-053110215610158
Pubmed

Control of Neuronal Ryanodine Receptor-Mediated Calcium Signaling by Calsenilin.

RYR2 RYR3

2.97e-053110229730765
Pubmed

Immunohistochemistry for NF2, LATS1/2, and YAP/TAZ Fails to Separate Benign From Malignant Mesothelial Proliferations.

NF2 YAP1

2.97e-053110227128293
Pubmed

The ryanodine receptor/calcium channel genes are widely and differentially expressed in murine brain and peripheral tissues.

RYR2 RYR3

2.97e-05311027876312
Pubmed

Bidirectional coupling between ryanodine receptors and Ca2+ release-activated Ca2+ (CRAC) channel machinery sustains store-operated Ca2+ entry in human T lymphocytes.

RYR2 RYR3

2.97e-053110222948152
Pubmed

Developmental changes in expression of the three ryanodine receptor mRNAs in the mouse brain.

RYR2 RYR3

2.97e-053110210788707
Pubmed

Ca(2+)-induced Ca2+ release in myocytes from dyspedic mice lacking the type-1 ryanodine receptor.

RYR2 RYR3

2.97e-05311027621815
Pubmed

Rac1-Mediated DNA Damage and Inflammation Promote Nf2 Tumorigenesis but Also Limit Cell-Cycle Progression.

NF2 YAP1

2.97e-053110227818180
Pubmed

Ku70 Binding to YAP Alters PARP1 Ubiquitination to Regulate Genome Stability and Tumorigenesis.

YAP1 XRCC6

2.97e-053110238862269
Pubmed

The p130 isoform of angiomotin is required for Yap-mediated hepatic epithelial cell proliferation and tumorigenesis.

NF2 YAP1

2.97e-053110224003254
Pubmed

Association between Serotonin-Related Polymorphisms in 5HT2A, TPH1, TPH2 Genes and Bipolar Disorder in Korean Population.

TPH2 TPH1

2.97e-053110220396435
Pubmed

Molecular identification of the ryanodine receptor pore-forming segment.

RYR2 RYR3

2.97e-053110210473538
Pubmed

Phenylalanine hydroxylase contributes to serotonin synthesis in mice.

TPH2 TPH1

2.97e-053110233993565
Pubmed

The Hippo pathway effectors TAZ/YAP regulate dicer expression and microRNA biogenesis through Let-7.

DICER1 YAP1

2.97e-053110224324261
Pubmed

Autoantibodies against aromatic amino acid hydroxylases in patients with autoimmune polyendocrine syndrome type 1 target multiple antigenic determinants and reveal regulatory regions crucial for enzymatic activity.

TPH2 TPH1

2.97e-053110223182718
Pubmed

Heterogeneous gene expression and functional activity of ryanodine receptors in resistance and conduit pulmonary as well as mesenteric artery smooth muscle cells.

RYR2 RYR3

2.97e-053110218434746
Pubmed

SPRY domains in ryanodine receptors (Ca(2+)-release channels).

RYR2 RYR3

2.97e-05311029204703
Pubmed

Association of TPH1, TPH2, and 5HTTLPR with PTSD and depressive symptoms.

TPH2 TPH1

2.97e-053110222483952
Pubmed

Ryanodine receptors are expressed in epidermal keratinocytes and associated with keratinocyte differentiation and epidermal permeability barrier homeostasis.

RYR2 RYR3

2.97e-053110221881589
Pubmed

Serotonin-reuptake inhibitors act centrally to cause bone loss in mice by counteracting a local anti-resorptive effect.

TPH2 TPH1

2.97e-053110227595322
Pubmed

Tryptophan hydroxylase 1 knockout and tryptophan hydroxylase 2 polymorphism: effects on hypoxic pulmonary hypertension in mice.

TPH2 TPH1

2.97e-053110217675372
Pubmed

Isoform-dependent formation of heteromeric Ca2+ release channels (ryanodine receptors).

RYR2 RYR3

2.97e-053110212213830
Pubmed

AP-3-dependent targeting of flippase ATP8A1 to lamellar bodies suppresses activation of YAP in alveolar epithelial type 2 cells.

AP3B1 YAP1

2.97e-053110233990468
Pubmed

TRIM65/NF2/YAP1 Signaling Coordinately Orchestrates Metabolic and Immune Advantages in Hepatocellular Carcinoma.

NF2 YAP1

2.97e-053110239005234
Pubmed

Isolation and characterisation of GTF2IRD2, a novel fusion gene and member of the TFII-I family of transcription factors, deleted in Williams-Beuren syndrome.

GTF2IRD2B GTF2IRD2

2.97e-053110215100712
Pubmed

Expression of the ryanodine receptor type 3 calcium release channel during development and differentiation of mammalian skeletal muscle cells.

RYR2 RYR3

2.97e-05311029242641
Pubmed

Association between tryptophan hydroxylase 2 polymorphism and anger-related personality traits among young Korean women.

TPH2 TPH1

2.97e-053110220628266
Pubmed

Genetic moderation of cocaine subjective effects by variation in the TPH1, TPH2, and SLC6A4 serotonin genes.

TPH2 TPH1

2.97e-053110228590957
Pubmed

Role of Nesprin-2 and RanBP2 in BICD2-associated brain developmental disorders.

BICD2 SYNE2

2.97e-053110236930595
Pubmed

RYR2 proteins contribute to the formation of Ca(2+) sparks in smooth muscle.

RYR2 RYR3

2.97e-053110215024040
Pubmed

A link between serotonin-related gene polymorphisms, amygdala activity, and placebo-induced relief from social anxiety.

TPH2 TPH1

2.97e-053110219052197
Pubmed

Calcineurin upregulates local Ca(2+) signaling through ryanodine receptor-1 in airway smooth muscle cells.

RYR2 RYR3

2.97e-053110225239916
Pubmed

Zinc transporter ZIP13 suppresses beige adipocyte biogenesis and energy expenditure by regulating C/EBP-β expression.

SLC39A13 PRDM16

2.97e-053110228854265
Pubmed

A gene-specific cerebral types 1, 2, and 3 RyR protein knockdown induces an antidepressant-like effect in mice.

RYR2 RYR3

2.97e-053110218643873
Pubmed

Identification of mutations in the cardiac ryanodine receptor gene in families affected with arrhythmogenic right ventricular cardiomyopathy type 2 (ARVD2).

RYR2 RYR3

2.97e-053110211159936
Pubmed

Chromosomal localization of murine ryanodine receptor genes RYR1, RYR2, and RYR3 by in situ hybridization.

RYR2 RYR3

2.97e-05311027959768
Pubmed

Serotonin in pre-implantation mouse embryos is localized to the mitochondria and can modulate mitochondrial potential.

TPH2 TPH1

2.97e-053110218304982
Pubmed

The organization of proteins in the human red blood cell membrane. A review.

RYR2 RYR3

2.97e-05311024600883
Pubmed

Essential roles of enteric neuronal serotonin in gastrointestinal motility and the development/survival of enteric dopaminergic neurons.

TPH2 TPH1

2.97e-053110221677183
InteractionCEP135 interactions

BICD2 MIA3 WASHC2C CEP162 GPATCH1 PPP1R13B CEP192 CEP164 AKAP9 GOLGB1

2.24e-0627210910int:CEP135
InteractionNIN interactions

BICD2 FLOT2 MIA3 TRIO CEP162 GPATCH1 PPP1R13B CLASP2 CEP192 CEP164 WDR3

3.98e-0635910911int:NIN
InteractionSASS6 interactions

BICD2 WASHC2C CEP162 GPATCH1 UBR4 CEP192 CEP164

2.53e-051591097int:SASS6
InteractionKRT8 interactions

BICD2 MIA3 CEP162 UBR4 PPP1R13B CEP192 AP3B1 AKAP9 CRYBG1 MTCL1 XRCC6

2.72e-0544110911int:KRT8
InteractionNDC80 interactions

BICD2 MIA3 CEP162 PPP1R13B CEP192 CEP164 AKAP9 SYNE2 MTCL1

5.01e-053121099int:NDC80
InteractionAMOT interactions

FKBP15 MIA3 WASHC2C UBR4 PPP1R13B CEP192 NF2 YAP1 MTCL1

5.01e-053121099int:AMOT
InteractionNUDT5 interactions

BICD2 IFI16 YAP1 MAPK6 XRCC6

5.39e-05751095int:NUDT5
Cytoband16p12.2

RBBP6 COG7 CHP2

9.80e-0537110316p12.2
GeneFamilyRyanodine receptors|Protein phosphatase 1 regulatory subunits

RYR2 RYR3

4.55e-053712287
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

FKBP15 ZFYVE16 PPP1R13B CEP192 AKAP9

7.26e-04181715694
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STXBP5L CYP7A1 ANO5 RYR2 RYR3 TRANK1 UNC79

3.81e-0718411072cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STXBP5L CYP7A1 ANO5 RYR2 RYR3 TRANK1 UNC79

3.81e-071841107ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STXBP5L CYP7A1 ANO5 RYR2 RYR3 TRANK1 UNC79

3.81e-0718411072b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellCOVID-19_Moderate-NK_activated|World / disease group, cell group and cell class

EFHD2 IFI16 SLFN12L TRANK1 ANKRD20A4P SYNE2 PARP9

4.10e-071861107ff8f32f69516bf785224fa12f8139a95359b0279
ToppCellMild|World / Condition, Lineage, Cell class and cell subclass

FLOT2 MIA3 SLFN12L TRANK1 AKAP9 SMARCC2 GOLGB1

6.03e-071971107476b0d0389f9fcd4614f6bb1f494281f467f6730
ToppCell(11)_FOXN4+-(2)_GFP_FOXI1|(11)_FOXN4+ / shred by cell type by condition

RBBP6 CEP162 AKAP9 SYNE2 PARP9 DHX29 GOLGB1

6.24e-07198110776d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

GK5 HELB SLFN12L AKAP9 ABCA5 SYNE2 GOLGB1

6.45e-071991107f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell(10)_Ciliated-(2)_GFP_FOXI1|(10)_Ciliated / shred by cell type by condition

RBBP6 CEP162 LCA5L AKAP9 SYNE2 PARP9 GOLGB1

6.45e-07199110761b1ed2db71b96157b92b7535d1955a4033098da
ToppCell(02)_MMP9/10+-(2)_GFP_FOXI1|(02)_MMP9/10+ / shred by cell type by condition

BICD2 IFI16 AKAP9 SYNE2 CRYBG1 PARP9 GOLGB1

6.45e-07199110718a7f9ced4364f45b184bd529f32ef02c27779d3
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

HELB SLFN12L AKAP9 SYNE2 CRYBG1 GOLGB1

4.26e-0617111062e9a20f8980b78325c52065a9c14ab3656267c05
ToppCellwk_20-22-Epithelial-Proximal_epithelial-Deuterosomal|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

CFAP47 CYP7A1 LCA5L ADGB TPH2 SYCP1

4.26e-06171110652aec5f6677fe2f7a36fb5b18117a4cffaeff58f
ToppCellCalu_3-infected|Calu_3 / Cell line, Condition and Strain

TRIO RBBP6 IFI16 TRANK1 SYNE2 PARP9

6.29e-0618311068f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCellControl-Myeloid-cDC1|Myeloid / Disease state, Lineage and Cell class

ANKRD20A2P ANKRD20A3P ANKRD20A8P DENND1B ANKRD20A4P CRYBG1

6.49e-061841106c6affa0b12510363258f65e46bf2d47bf4a8e75f
ToppCellCOPD-Myeloid-cDC1|World / Disease state, Lineage and Cell class

ANKRD20A2P ANKRD20A3P ANKRD20A8P DENND1B ANKRD20A4P CRYBG1

6.49e-06184110642d7ce104cd7bcb83fbbbd0e7d3267ad07edfa94
ToppCellIPF-Myeloid-cDC1|World / Disease state, Lineage and Cell class

ANKRD20A2P ANKRD20A3P ANKRD20A8P DENND1B ANKRD20A4P CRYBG1

6.90e-061861106962c2dada19185628ead77c32fcb07fa95114247
ToppCellControl-Myeloid-cDC1|Control / Disease state, Lineage and Cell class

ANKRD20A2P ANKRD20A3P ANKRD20A8P DENND1B ANKRD20A4P CRYBG1

6.90e-061861106b05c394aa3573ba855abc3066739ca193883b0c3
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BRINP3 SPTBN2 ACOT12 CRYBG1 PRDM16 SLC16A10

7.12e-061871106e3095455d2f255854f339f6b05fa87852af0700f
ToppCellT_cells-ISG-high_CD4+_T_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

IFI16 HELB SLFN12L TRANK1 SYNE2 PARP9

7.34e-0618811066f8946d4710f6e32c937213f99b790b098b8819c
ToppCellIPF-Myeloid-cDC1|IPF / Disease state, Lineage and Cell class

ANKRD20A2P ANKRD20A3P ANKRD20A8P DENND1B ANKRD20A4P CRYBG1

7.34e-0618811062331a2bae1383820d598e93aa86c75b101069bac
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BRINP3 SPTBN2 ACOT12 CRYBG1 PRDM16 SLC16A10

7.57e-0618911063a295c215b5c18e7c673f92b7af5be523421682c
ToppCellCOPD-Myeloid-cDC1|Myeloid / Disease state, Lineage and Cell class

ANKRD20A2P ANKRD20A3P ANKRD20A8P DENND1B ANKRD20A4P CRYBG1

8.03e-0619111063480e6d27dd4291765bbbb2acdb6a2e4f02c8085
ToppCellCOPD-Endothelial-VE_Capillary_B|Endothelial / Disease state, Lineage and Cell class

WASHC2C ANKRD20A2P ANKRD20A3P IFI16 ANKRD20A4P NOSTRIN

9.58e-06197110630dbc05ea66892d2e18ff375ffa86d1db7bc4083
ToppCellAT2_cells-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

SPTBN2 ANKRD20A2P ANKRD20A3P RYR3 ANKRD20A4P

1.86e-051311105ff4e618bd944f852bbd34438f740187aca82460f
ToppCell(08)_Brush+PNEC-(2)_GFP_FOXI1|(08)_Brush+PNEC / shred by cell type by condition

RBBP6 AKAP9 SYNE2 PARP9 GOLGB1

2.39e-051381105817e3f639604ea95adae01e8685ffaa2e0aff7a8
ToppCellE18.5-samps-Endothelial-Mature_fetal_endothelial-capillary_endothelial_Hpgd-CA4_high|E18.5-samps / Age Group, Lineage, Cell class and subclass

STXBP5L COG7 INTS3 RAB44 RYR2

4.03e-051541105212c340a096a3a9669d1aebd61c045cf1402a868
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

STXBP5L SPTBN2 ANO5 UNC79 TPH1

4.70e-0515911057747cef94c55144fddcd024a7495318357f1351b
ToppCellfacs-Pancreas-Exocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CERK ZFYVE16 ABCA5 ALOXE3 DHX29

5.29e-051631105132aece9c79499b4bb3c2bde68d3d7202e1d8772
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BRINP3 SPTBN2 CRYBG1 PRDM16 SLC16A10

7.81e-051771105f35b04c3557ebbdeba37dec54c8f45880eafb422
ToppCellfacs-Kidney-nan-24m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A2 SNX33 RAB44 SVEP1 UNC79

8.45e-051801105f9f8245cbcdea18c15e2976c85b72c6807309787
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SPTBN2 ACOT12 CRYBG1 PRDM16 SLC16A10

8.45e-051801105023ec0b080c8a5cd0f36e83c6b17d4be3c01edb5
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c11-GNLY|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SLC39A13 ZHX1-C8orf76 TRANK1 ANKRD20A4P SYNE2

8.67e-0518111055cecbafc29cc95896e6ccb2c74d9237b9aaece69
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BRINP3 SPTBN2 CRYBG1 PRDM16 SLC16A10

8.67e-051811105aa233b652921848af2257cc3687a7a09c3acfb67
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

BRINP3 SPTBN2 CRYBG1 PRDM16 SLC16A10

8.67e-051811105b7c85fbef3c06d5dc32a2a58f8d3dfabf1d79d9f
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BRINP3 SPTBN2 ACOT12 CRYBG1 PRDM16

9.13e-051831105b5ede5a0048c585b73c00e88aeddbcaf669347b1
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_OPC-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FLOT2 SHOX ANKRD20A3P ANKRD20A8P CHP2

9.61e-051851105d42dcc92a34fcdabf112565fbd5fd26cbd4de58a
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Endothelial_Myeloid-Endo-Endothelial-Endo_L2-5_CLDN5|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CLIC4 SLFN12L SYNE2 PARP9 NOSTRIN

9.86e-051861105422d24e3e1a9397bb7d5c7ef75de2fd7ae8e136d
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Endothelial_Myeloid-Endo|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CLIC4 SLFN12L SYNE2 PARP9 NOSTRIN

9.86e-05186110565da0666a10a59f8cc379589860a2e98fe487754
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Endothelial_Myeloid-Endo-Endothelial|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CLIC4 SLFN12L SYNE2 PARP9 NOSTRIN

9.86e-051861105dc84fef1ca2f5d5d818b76a3321559e87d1c4a4d
ToppCellControl-T_cells|Control / group, cell type (main and fine annotations)

IFI16 HELB SLFN12L SYNE2 CRYBG1

1.01e-041871105f4e8e0eba58da89b56587667555a5d4754e108c7
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BRINP3 SPTBN2 CRYBG1 PRDM16 SLC16A10

1.01e-0418711052d17408b3b5f09d135084fd7ccce98e6b5ca632b
ToppCellLA-13._Vascular_Smooth_Muscle|LA / Chamber and Cluster_Paper

CLASP2 RYR2 RYR3 YAP1 PRDM16

1.04e-04188110534e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCellIPF-Myeloid-cDC1|Myeloid / Disease state, Lineage and Cell class

ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A4P CRYBG1

1.04e-04188110547bb6caf84f70a1cda7d09803afdfd5182772e66
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

BRINP3 SPTBN2 CRYBG1 PRDM16 SLC16A10

1.04e-04188110558ccb31cdf43167872ef0fc737e6f9c51ee2e060
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

COL6A2 ZNF536 BRINP3 RYR3 MTCL1

1.04e-0418811054d1e5f85342ae550086609d7680e32730b78b5d2
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

BRINP3 SPTBN2 CRYBG1 PRDM16 SLC16A10

1.06e-041891105c9565e962a13a7713056ec3dbb1b67d24f9889c7
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ZNF536 BRINP3 RYR3 TRANK1 MTCL1

1.06e-041891105da9ecc0d7b81c1901f30f97bb44112dc85444a66
ToppCellMesenchymal-airway_smooth_muscle_cell|World / Lineage, Cell type, age group and donor

COL6A2 ZNF536 BRINP3 RYR3 MTCL1

1.09e-041901105645e56b02edc3702c7db917b8ecd5eed0decaf71
ToppCellCalu_3-infected-SARSCoV2|infected / Cell line, Condition and Strain

RBBP6 IFI16 TRANK1 SYNE2 PARP9

1.12e-0419111052da876d26f37a00dbdf1ee79d724306e8b20f304
ToppCellCOPD-Myeloid-cDC1|COPD / Disease state, Lineage and Cell class

ANKRD20A2P ANKRD20A3P ANKRD20A8P DENND1B ANKRD20A4P

1.14e-041921105bd3d00b094d92463b06023361a71240851a542b8
ToppCellCOPD-Lymphoid-T|World / Disease state, Lineage and Cell class

RYR2 HELB SLFN12L SYNE2 CRYBG1

1.14e-041921105eb4909574fb5fc91399463523e2737095773200a
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

COL6A2 EFHD2 SLFN12L ANKRD20A4P SYNE2

1.14e-041921105ce867b6e78c1d8f30dff81bf572a78a897bc7625
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell-T_gdT_c14-TRDV2|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

COL6A2 EFHD2 SLFN12L ANKRD20A4P SYNE2

1.14e-04192110558a7829b411b02b422ef75e2277a868969cc23e8
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c08-IL2RB|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

EFHD2 GK5 SLFN12L ANKRD20A4P SYNE2

1.17e-04193110554604c2c5dce2ff6f3ec7ca82b595b09b8cdafe8
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_ILC-NK_cell|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

EFHD2 GK5 SLFN12L ANKRD20A4P SYNE2

1.23e-04195110598b02beafe1d418442e41f85cbf0c7b194fe5957
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_ILC|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

EFHD2 GK5 SLFN12L ANKRD20A4P SYNE2

1.23e-0419511059ecae6c26a0d0607d101ccf1c38f0b23c5a256a8
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MIA3 UGGT1 AKAP9 ABCA5 GOLGB1

1.23e-0419511057796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellCOPD-Lymphoid-T|COPD / Disease state, Lineage and Cell class

RYR2 HELB SLFN12L SYNE2 CRYBG1

1.26e-04196110530e53b8050d2a041f855d0e39bbd8f923c64c489
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

EFHD2 GK5 SLFN12L ANKRD20A4P SYNE2

1.26e-0419611059b3848dd4256cd6d9a21ef6bfdbd0cb7c0030005
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_ILC-NK_cell|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

EFHD2 GK5 SLFN12L ANKRD20A4P SYNE2

1.26e-04196110578b28b263deaa43590b38597186222c6447ad25f
ToppCellMild|World / Disease group and Cell class

IFI16 HELB SLFN12L TRANK1 PARP9

1.26e-0419611055e4ed4a5a437cfa002b92775992a791e27aa4c27
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COL6A2 TRIO WEE1 CLIC4 RYR3

1.26e-041961105b8b9801181d7604871b48aebacb295d0a57a5eaf
ToppCellMild-CD8+_T_activated|World / Disease group and Cell class

IFI16 HELB SLFN12L TRANK1 PARP9

1.26e-04196110579632190e44fcef9d7c11d9b9e37f2ebf0e6e255
ToppCellMild-CD4+_T_activated|World / Disease group and Cell class

IFI16 HELB SLFN12L TRANK1 PARP9

1.26e-041961105417b4fc2e4388f34c410576131b02936f93e46b6
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_ILC|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

EFHD2 GK5 SLFN12L ANKRD20A4P SYNE2

1.26e-0419611053e78e307c9c991c1aadc85c61d401431cf75eaec
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

EFHD2 GK5 SLFN12L ANKRD20A4P SYNE2

1.26e-041961105f0566f2ef96584ed6d9247b149218376fb509915
ToppCellBAL-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IFI16 HELB SLFN12L TRANK1 SYNE2

1.29e-0419711050b4fdf0131dd67a86ee3209fa66db0ca2e01a10e
ToppCellmild-low-quality_cells|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

GK5 HELB SLFN12L ABCA5 SYNE2

1.29e-041971105e4331969bd911d1ebb5453f40a7057297b5389b4
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c08-IL2RB|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

EFHD2 GK5 SLFN12L ANKRD20A4P SYNE2

1.29e-041971105bc37b8919f98dc18c2200834405f06823d965d78
ToppCellsevere_influenza-NK|World / disease group, cell group and cell class (v2)

COL6A2 EFHD2 GK5 SLFN12L SYNE2

1.29e-0419711058e86a1ee0418e153d4f0bf291006cffc6cf36f71
ToppCellBAL-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IFI16 HELB SLFN12L TRANK1 SYNE2

1.29e-041971105b3876076684781fb8384117f2cf367d828985986
ToppCellCOVID-19_Severe-NK_activated|World / disease group, cell group and cell class

EFHD2 IFI16 GK5 SLFN12L SYNE2

1.29e-041971105a60db36d1a192998e3ded63e0c7c08d41689f95f
ToppCellHealthy_donor-NK|World / disease group, cell group and cell class (v2)

COL6A2 EFHD2 GK5 SLFN12L SYNE2

1.32e-0419811054c9c40e91173836ad0df2eba635a4cb3385e80c6
ToppCellmild_COVID-19_(asymptomatic)-NK|World / disease group, cell group and cell class (v2)

COL6A2 EFHD2 GK5 SLFN12L SYNE2

1.32e-0419811057a0aac52d785037455e068e1b25de4b2bf0fff79
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_activated|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

EFHD2 IFI16 GK5 TRANK1 SYNE2

1.32e-0419811050e918e9db9b884f5328d438e90efe065e27266ee
ToppCellmild_COVID-19_(asymptomatic)-NK|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

COL6A2 EFHD2 GK5 SLFN12L SYNE2

1.32e-0419811051e43181c13e054570046c7a973ddc1c586e259b0
ToppCell10x5'v1-week_14-16-Myeloid_neutrophil-granulo-neutrophil-neutrophil|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

CCPG1 PPP2R5A SYNE2 NINJ1 FMNL1

1.32e-041981105e76061e66f6d60f5735962aa7777dda8958caed9
ToppCellControl_saline-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|Control_saline / Treatment groups by lineage, cell group, cell type

COL6A2 SVEP1 RYR2 RYR3 SYCP1

1.32e-0419811050c4d2c68a42f8a9e964e2dd28092fe75f5216834
ToppCellParenchymal-NucSeq-Immune_Myeloid-Dendritic_cell-DC_1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

EFHD2 ANKRD20A2P ANKRD20A3P ANKRD20A4P FMNL1

1.32e-041981105fa5c15a656d4132950092919600e270f1fd79abf
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_activated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

EFHD2 IFI16 GK5 TRANK1 SYNE2

1.32e-041981105ce92d5fbc2eac27fb246b044fb1914ab92506275
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_activated|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

EFHD2 IFI16 GK5 TRANK1 SYNE2

1.32e-041981105fed823d6e684d113bcc9ff3cd1803bb001aa02fa
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_activated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

EFHD2 IFI16 GK5 TRANK1 SYNE2

1.32e-0419811051ef3a6bd681c223eed58300348adfef89df5563c
ToppCellCV-Mild-1|CV / Virus stimulation, Condition and Cluster

IFI16 HELB TRANK1 SYNE2 PARP9

1.32e-0419811054b078714c49e7befb7b113d72485e712236d35fa
ToppCellsevere-NK|severe / disease stage, cell group and cell class

EFHD2 GK5 SLFN12L ANKRD20A4P SYNE2

1.32e-041981105cb505077dc5bdf3fdd513bb9032e32bb9644c004
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

SHOX2 EFHD2 RYR2 ANKRD20A4P

1.34e-0410511048f31edf4183587f5b53941475453c5aa49f10bbd
ToppCellCOVID-19_Severe-Lymphoid_T/NK-NK_activated|COVID-19_Severe / Disease group, lineage and cell class

EFHD2 IFI16 GK5 TRANK1 SYNE2

1.35e-041991105edf5f80b4c299e6bf462675f2cd3329d86c923d8
ToppCellCOVID_non-vent-Lymphocytic-ILC|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

EFHD2 GK5 SLFN12L TRANK1 SYNE2

1.35e-041991105df4f7d5be099e3e6054f3b812ccf70251664e4c0
ToppCell(09)_Interm._secr.>cil.-(2)_GFP_FOXI1|(09)_Interm._secr.>cil. / shred by cell type by condition

RBBP6 AKAP9 SYNE2 PARP9 GOLGB1

1.35e-041991105fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCellCOVID_non-vent-Lymphocytic-ILC-NK_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

EFHD2 GK5 SLFN12L TRANK1 SYNE2

1.35e-041991105ed35d747f11f6ea6a5cb7061057f0a98d9e0db99
ToppCellCOVID-19_Severe-NK_activated|COVID-19_Severe / disease group, cell group and cell class

EFHD2 IFI16 GK5 SLFN12L SYNE2

1.35e-041991105bda28d975f4017ec5bded1d3c72310eabc5aac07
ToppCellHealthy/Control-NK|World / Disease group and Cell class

COL6A2 EFHD2 GK5 SLFN12L SYNE2

1.35e-04199110587af9c38938dc2db0f9cf9f3676895d2a8b5d7e6
ToppCellCOVID-19_Moderate|World / disease group, cell group and cell class

HELB SLFN12L TRANK1 SYNE2 PARP9

1.35e-041991105952fac67588ad5676f5939e3c7f8bac803c27064
ToppCell(01)_IL1RL1+-(2)_GFP_FOXI1|(01)_IL1RL1+ / shred by cell type by condition

RBBP6 AKAP9 SYNE2 DHX29 GOLGB1

1.35e-041991105a2f7d0cabf35b80fe239fae34a77bf9344d5d743
ToppCellHealthy_donor-NK|Healthy_donor / disease group, cell group and cell class (v2)

COL6A2 EFHD2 GK5 SLFN12L SYNE2

1.35e-0419911054892d85f7c8c00e5afdcea2cd7bae0074322fa52
ToppCellLPS_IL1RA-Endothelial-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

CLIC4 IFI16 PPP2R5A SYNE2 NOSTRIN

1.38e-04200110572ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCellmild-CD8+_Tem|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

COL6A2 SLFN12L TRANK1 SYNE2 PARP9

1.38e-042001105d8aec4904c9420b8f9d7508658ba1e36c66cdfcc
ToppCellLPS_IL1RA-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

CLIC4 IFI16 PPP2R5A SYNE2 NOSTRIN

1.38e-0420011055c092b2ecc081b5d04476c56333c338cd89ab984
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

IFI16 AKAP9 SYNE2 PARP9 GOLGB1

1.38e-04200110512f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellSkin-Keratinocytes|Skin / Skin and Kidney Cells in Lupus Nephritis Patients.

BICD2 SPTBN2 UBR4 CHP2 XRCC6

1.38e-04200110559d72395199bc30df0e811fbc99149694e208860
ToppCellmild-gd_T|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

COL6A2 EFHD2 SLFN12L AKAP9 SYNE2

1.38e-042001105109f673a4967ffa52270a0b4f818b3461288db44
ToppCellVE|World / Condition, Cell_class and T cell subcluster

EFHD2 IFI16 TRANK1 SYNE2 PARP9

1.38e-0420011058ae7cb81de3ffac5acdf3466d4b516d80cac95d3
ComputationalNeighborhood of TINF2

SIN3A SNX33 NF2 DHX29

8.12e-0541614GCM_TINF2
DrugMethotrexate [59-05-2]; Down 200; 8.8uM; HL60; HG-U133A

RBBP6 COG7 CLIC4 HMGCS1 PPP2R5A NF2 PRKAB1 TACC3

3.87e-0618911082041_DN
Drugalpha-difluoromethyldopa

TPH2 TPH1

2.31e-0521102CID000129677
DrugSC-48274

TPH2 TPH1

2.31e-0521102CID000040914
Drug17-DMAG; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA

BRINP3 WEE1 RBBP6 PPP2R5A WBP4 SMARCC2 TACC3

4.30e-0519311071051_DN
DrugAir Pollutants, Occupational

FKBP15 WASHC2C GART CLIC4 HMGCS1 ANKRD20A8P IFI16 IFNAR1 GTF2IRD2B TRANK1 NINJ1 PARP9 MAPK6

4.82e-0572511013ctd:D000395
DrugThalidomide [50-35-1]; Down 200; 15.4uM; HL60; HG-U133A

COG7 UGGT1 GART HMGCS1 IFI16 EDAR WBP4

5.05e-0519811071411_DN
Drug2,4,5-trihydroxymethamphetamine

TPH2 TPH1

6.92e-0531102CID000131985
Drug2-hydroxycarbazole

RYR2 RYR3

6.92e-0531102CID000093551
Drug2,4,5-trihydroxyamphetamine

TPH2 TPH1

6.92e-0531102CID000126234
Drug4-methyl-alpha-ethyl-m-tyramine

TPH2 TPH1

6.92e-0531102CID000168028
DrugAC1Q5QKX

TPH2 TPH1

6.92e-0531102CID000164302
Drugcis-diammineplatinum(II

RYR2 RYR3

6.92e-0531102CID000159790
Drug4-methylaminorex

EDAR TPH1

6.92e-0531102CID000092196
Drug2-hydroxyheptanoic acid

RYR2 RYR3

6.92e-0531102CID002750949
DrugRyanodyl 3-(pyridine-3-carboxylate

RYR2 RYR3

6.92e-0531102CID005748312
Drug8N3-cADPR

RYR2 RYR3

6.92e-0531102CID000127713
DrugFmtrp

TPH2 TPH1

6.92e-0531102CID000126435
Drugaminodantrolene

RYR2 RYR3

6.92e-0531102CID009570289
Drug2-hydroxy-4,5-methylenedioxyamphetamine

TPH2 TPH1

6.92e-0531102CID000126859
Diseasecongenital myopathy 1A (implicated_via_orthology)

RYR2 RYR3

3.47e-0531012DOID:3529 (implicated_via_orthology)
Diseasemalignant hyperthermia (implicated_via_orthology)

RYR2 RYR3

3.47e-0531012DOID:8545 (implicated_via_orthology)
Diseasecoloboma (implicated_via_orthology)

NF2 YAP1

3.20e-0481012DOID:12270 (implicated_via_orthology)
Diseasealcohol use disorder (implicated_via_orthology)

CLIC4 RYR2 RYR3 SMARCC2 UNC79

5.68e-041951015DOID:1574 (implicated_via_orthology)
Diseaselevel of Ceramide (d40:1) in blood serum

CYP7A1 SYNE2

6.25e-04111012OBA_2045185
Diseasebreast carcinoma

CEP162 SPTBN2 CEP192 SIN3A GTF2IRD2B AKAP9 NF2 GTF2IRD2 MTCL1 BBOX1 XRCC6

7.38e-04101910111EFO_0000305
Diseaserostral middle frontal gyrus volume measurement

ADGB MAPK6

1.03e-03141012EFO_0010328
Diseasesuccinylcarnitine measurement

ZNF536 SUCLG2

1.35e-03161012EFO_0020020
Diseasechin morphology measurement

ZNF536 DICER1 DENND1B

1.80e-03701013EFO_0007842
Diseasesquamous cell carcinoma (is_marker_for)

RIPK1 XRCC6

1.91e-03191012DOID:1749 (is_marker_for)
Diseasecancer (implicated_via_orthology)

RBBP6 SIN3A PPP2R5A YAP1 SMARCC2

2.32e-032681015DOID:162 (implicated_via_orthology)
Diseasesex interaction measurement, COVID-19

ZNF536 MAPK6

2.33e-03211012EFO_0008343, MONDO_0100096
DiseaseArthrogryposis

BICD2 VPS8

2.33e-03211012C0003886
DiseaseDisproportionate short stature

SHOX ANO5 SLC39A13

2.37e-03771013C0878659
Diseaseperiodontal measurement

ANO5 IFI16

3.05e-03241012EFO_0007780

Protein segments in the cluster

PeptideGeneStartEntry
KDMDKFSGLFSALDS

ABCA5

751

Q8WWZ7
DFEESDEFKLFMKRL

BRINP3

316

Q76B58
KMKSSVFDEDKTFVA

AKAP9

911

Q99996
NSMEDIKFSTRKFLD

CLIC4

166

Q9Y696
MDFSKFLADDFDVKE

COG7

1

P83436
MSSAISKVKDENEFL

ANKRD20A8P

646

Q5CZ79
FASFMESDASLKQVK

ANO5

491

Q75V66
LKEDAATFSSLRAMF

BICD2

736

Q8TD16
STFDMDKLKSTLKQF

CARNMT1

151

Q8N4J0
LFENKIFSLEKMADS

ADGB

426

Q8N7X0
MSSAISKVKDENEFL

ANKRD20A4P

646

Q4UJ75
FMADTKIADSKRAFE

FLOT2

206

Q14254
EDTFNNLMKESSKFD

ACOT12

151

Q8WYK0
NLMKESSKFDDLIFD

ACOT12

156

Q8WYK0
EKFKSSSLSFTVFDM

ARL6

56

Q9H0F7
DSSTLDIDFKFMEDI

DICER1

886

Q9UPY3
LQAFSFKTKDIEDAM

DHX29

131

Q7Z478
SAEIERFSAMFQEKK

PPP1R13B

211

Q96KQ4
MAKSFTSEDDLVKLQ

AP3B1

521

O00203
FDRDVEKAFMKASSE

HMGCS1

311

Q01581
EKAFMKASSELFSQK

HMGCS1

316

Q01581
SAKSKSMVDELFAEI

RAP2C

146

Q9Y3L5
AKFSFLGSKEESEMI

RAB44

71

Q7Z6P3
EAHKMKFSDLFSLAE

INTS3

961

Q68E01
SKNLSDDMKEVAFSV

MTCL1

1596

Q9Y4B5
TDLEIYKAFSSEMAK

PARP9

471

Q8IXQ6
DRLYSSAEFKEKLDM

GUF1

46

Q8N442
MSSAISKVKDENEFL

ANKRD20A2P

646

Q5SQ80
EIEDKMKGFSFKEDT

C8orf76

296

Q96K31
SDFLENLMSTEKKTE

NUDT19

316

A8MXV4
SFQEMESDKKFALTK

ALOXE3

161

Q9BYJ1
VVMFSEKDEFEKLTA

EDAR

246

Q9UNE0
MDLFRAIFASSSDEK

GPATCH1

751

Q9BRR8
MDEKLNKSSVFSDAV

IFNAR1

411

P17181
KFFSRKEDTEMLETE

MAPK6

631

Q16659
SIMFESEKAAVEFNK

FKBP15

151

Q5T1M5
FGSSDHLEKLFKMDE

MANSC1

176

Q9H8J5
FRDKKSSLMEELFGS

LCA5L

591

O95447
SKLDEFTNDFAKELM

RBBP6

656

Q7Z6E9
MDAESITFKSVSEKD

RBBP6

991

Q7Z6E9
IGDSLSFDFKDTDMK

NF2

501

P35240
YASKKSAAESMLDIA

NINJ1

41

Q92982
SQATAEFEKAMKELA

PEX19

81

P40855
MSSAISKVKDENEFL

ANKRD20A3P

646

Q5VUR7
ETFDAMKNSTKEFVR

CCPG1

491

Q9ULG6
KKFQFTSKHMEDEDS

CERK

456

Q8TCT0
MTLFSDLVAEKFIDD

COL6A2

786

P12110
EFVDLMNSKESKFTF

BBOX1

316

O75936
FMKELSDDSFENSDK

CEP162

16

Q5TB80
ISNTTDKDEKFSVFM

DNAH14

3361

Q0VDD8
FTKKSEDTISKMNDF

IFI16

441

Q16666
LTADKGKTEDTFFMS

CEP192

681

Q8TEP8
ELDMSDFEEQFKTKS

FMNL1

671

O95466
LFTDAAETEKMAKSL

GK5

351

Q6ZS86
MFLNDTLSTFDDLEK

CYP7A1

261

P22680
FDSSSDMEKFTEIIK

CRYBG1

691

Q9Y4K1
MIKEVDEDFDSKLSF

EFHD2

136

Q96C19
KRFFESLEEIDSFMS

GTF2IRD2

721

Q86UP8
KRFFESLEEIDSFMS

GTF2IRD2B

721

Q6EKJ0
AAAKSLDFFRSMDDI

DENND1B

586

Q6P3S1
TFLALEKMFLDSKEE

SLC39A13

161

Q96H72
FFDMFLKLKDLTSSD

RYR2

4016

Q92736
FPDFSMDLKDKSEEF

CFAP47

1096

Q6ZTR5
MSFHAASESLKFLKD

HELB

326

Q8NG08
FSDAKSQKDTAALMD

NOSTRIN

336

Q8IVI9
NSMEKSFSDLFKRFE

TACC3

716

Q9Y6A5
SLLSFMESFNEEKKS

SYNE2

331

Q8WXH0
MESFNEEKKSFLDVL

SYNE2

336

Q8WXH0
SFESFEEMLQDKLKV

MIA3

226

Q5JRA6
EKLESFAAMKADSGS

PRDM16

906

Q9HAZ2
CLKEKFMDEDLSFFS

PRAMEF22

156

A3QJZ6
DRVDTFKAFSKKMDD

SNX33

376

Q8WV41
DFLDIMKEFKSQSID

SIN3A

146

Q96ST3
MEELTAFVSKSFDQK

SHOX2

1

O60902
MEELTAFVSKSFDQK

SHOX

1

O15266
ASLSKFSYIDMDKEL

VPS8

31

Q8N3P4
KMKSSDFLESAELDS

RIPK1

11

Q13546
DTDLMKKFSEAFETT

SVEP1

811

Q4LDE5
AAAKSALEEFSKMKE

SMARCC2

691

Q8TAQ2
KDSKEAITALYFMDS

STXBP5L

826

Q9Y2K9
LFDFMDSVSDLKSKE

PPP2R5A

81

Q15172
KKTDFEVFDALMVDS

PRKAB1

156

Q9Y478
KKAVTFDLSDMDSLS

CEP164

1216

Q9UPV0
AVSFVEFTKSLEKMD

CHP2

171

O43745
FNKSALKEAMFDDDA

CLASP2

1031

O75122
ETLKVLKMFTDFLSF

ATP11C

336

Q8NB49
SESFEDAKEKMREFT

TPH1

376

P17752
DSLIFLVDASKAMFE

XRCC6

36

P12956
AEFRQKDIFAMDDKS

SUCLG2

266

Q96I99
SSLFMDTEKSGKREF

WEE1

211

P30291
NASAALEFLKDMEKT

SLFN12L

156

Q6IEE8
AADAAIKKLEDFMST

SPTBN2

1206

O15020
MSAFSEAALEKKLSE

RPRD1A

1

Q96P16
KFFDMFLKLKDLTSS

RYR3

3911

Q15413
KRKMAFEFDINSDSS

SYCP1

881

Q15431
FTKDTARFKDELDIM

TRAPPC6B

51

Q86SZ2
ASKEFAAMEAAALKA

WBP4

61

O75554
MESVLAATKLDKESF

YAP1

486

P46937
AKSIFDDDMDDIFST

WASHC2C

1266

Q9Y4E1
KDRMGIDSSDKVDFF

ACP6

236

Q9NPH0
AQLESSKRFAKEFMD

GART

101

P22102
VSESFEEAKEKMRDF

TPH2

421

Q8IWU9
FMDSFVLSSLKKEKD

ZNF536

921

O15090
TKMFKAEALLSQDAD

ZFP69B

36

Q9UJL9
MFFADATSHLEEKKR

WDR3

916

Q9UNX4
KTDENKDFDDSMFVK

TRANK1

1681

O15050
EAADKALKTFQEEFM

UBR4

5136

Q5T4S7
EDKMKGFSFKEDTLL

ZHX1-C8orf76

266

Q96EF9
FKEVFESSKMDFILS

UGGT1

861

Q9NYU2
LFEMSLVFSKEVKDS

TRIO

1511

O75962
MDSYFKAAVSDLDKL

ZFYVE16

1

Q7Z3T8
KFMAKDESSAESDIS

UNC79

1286

Q9P2D8
KFQSLMSEKDSLSEE

GOLGB1

1741

Q14789
TFGSKDDDKMVFKTA

SLC16A10

101

Q8TF71