Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	microtubule-based process	KIF20A DNHD1 TEKT2 SPEM3 DST IQCA1 DYNC2H1 SPEF2 CEP250 HAUS5 TPX2 MACF1 E2F4 CNTROB CCDC39 TTLL7	4.13e-06	1058	83	16	GO:0007017
GeneOntologyBiologicalProcess	microtubule cytoskeleton organization	KIF20A TEKT2 DST IQCA1 SPEF2 CEP250 HAUS5 TPX2 E2F4 CNTROB CCDC39 TTLL7	2.99e-05	720	83	12	GO:0000226
MousePheno	enlarged stomach	ANKRD20A4P ANKRD20A3P ANKRD20A8P ANKRD20A1	1.88e-05	33	68	4	MP:0003883
Domain	CH	EHBP1L1 DST SPEF2 SPTBN2 MACF1 DMD SMTN	2.63e-08	73	80	7	PS50021
Domain	CH-domain	EHBP1L1 DST SPEF2 SPTBN2 MACF1 DMD SMTN	3.18e-08	75	80	7	IPR001715
Domain	Spectrin	DST TRIO SPTBN2 MACF1 DMD	4.02e-08	23	80	5	PF00435
Domain	Spectrin_repeat	DST TRIO SPTBN2 MACF1 DMD	1.39e-07	29	80	5	IPR002017
Domain	Spectrin/alpha-actinin	DST TRIO SPTBN2 MACF1 DMD	2.34e-07	32	80	5	IPR018159
Domain	SPEC	DST TRIO SPTBN2 MACF1 DMD	2.34e-07	32	80	5	SM00150
Domain	CH	EHBP1L1 DST SPTBN2 MACF1 DMD SMTN	3.45e-07	65	80	6	SM00033
Domain	CH	EHBP1L1 DST SPTBN2 MACF1 DMD SMTN	5.38e-07	70	80	6	PF00307
Domain	-	EHBP1L1 DST SPTBN2 MACF1 DMD SMTN	5.86e-07	71	80	6	1.10.418.10
Domain	Actinin_actin-bd_CS	DST SPTBN2 MACF1 DMD	2.60e-06	23	80	4	IPR001589
Domain	ACTININ_2	DST SPTBN2 MACF1 DMD	2.60e-06	23	80	4	PS00020
Domain	ACTININ_1	DST SPTBN2 MACF1 DMD	2.60e-06	23	80	4	PS00019
Domain	TMEM191C	TMEM191B TMEM191C	1.81e-05	2	80	2	PF15194
Domain	TMEM191B/C	TMEM191B TMEM191C	1.81e-05	2	80	2	IPR028186
Domain	EF-hand-dom_pair	TCHH DST SWAP70 SPEF2 ITSN1 MACF1 DMD	2.29e-04	287	80	7	IPR011992
Domain	-	DST MACF1	2.69e-04	6	80	2	3.90.1290.10
Domain	GAR	DST MACF1	2.69e-04	6	80	2	PS51460
Domain	-	DST MACF1	2.69e-04	6	80	2	3.30.920.20
Domain	GAS_dom	DST MACF1	2.69e-04	6	80	2	IPR003108
Domain	GAS2	DST MACF1	2.69e-04	6	80	2	PF02187
Domain	GAS2	DST MACF1	2.69e-04	6	80	2	SM00243
Domain	Ank_2	ANKRD35 ANKRD20A4P TONSL ANKRD20A2P ANKRD20A3P ANKRD20A1	3.21e-04	215	80	6	PF12796
Domain	Plectin_repeat	DST MACF1	3.75e-04	7	80	2	IPR001101
Domain	Plectin	DST MACF1	3.75e-04	7	80	2	PF00681
Domain	PLEC	DST MACF1	3.75e-04	7	80	2	SM00250
Domain	Ank	ANKRD35 ANKRD20A4P TONSL ANKRD20A2P ANKRD20A3P ANKRD20A1	4.39e-04	228	80	6	PF00023
Domain	PH	SWAP70 TRIO ITSN1 SPTBN2 ARHGEF18 OSBP2	4.49e-04	229	80	6	PF00169
Domain	-	ANKRD35 ANKRD20A4P TONSL ANKRD20A2P ANKRD20A3P ANKRD20A1	6.83e-04	248	80	6	1.25.40.20
Domain	ANK	ANKRD35 ANKRD20A4P TONSL ANKRD20A2P ANKRD20A3P ANKRD20A1	7.27e-04	251	80	6	SM00248
Domain	ANK_REPEAT	ANKRD35 ANKRD20A4P TONSL ANKRD20A2P ANKRD20A3P ANKRD20A1	7.58e-04	253	80	6	PS50088
Domain	Ankyrin_rpt-contain_dom	ANKRD35 ANKRD20A4P TONSL ANKRD20A2P ANKRD20A3P ANKRD20A1	7.73e-04	254	80	6	IPR020683
Domain	ANK_REP_REGION	ANKRD35 ANKRD20A4P TONSL ANKRD20A2P ANKRD20A3P ANKRD20A1	7.73e-04	254	80	6	PS50297
Domain	Ankyrin_rpt	ANKRD35 ANKRD20A4P TONSL ANKRD20A2P ANKRD20A3P ANKRD20A1	9.08e-04	262	80	6	IPR002110
Domain	PH	SWAP70 TRIO ITSN1 SPTBN2 ARHGEF18 OSBP2	1.23e-03	278	80	6	SM00233
Domain	PH_DOMAIN	SWAP70 TRIO ITSN1 SPTBN2 ARHGEF18 OSBP2	1.26e-03	279	80	6	PS50003
Domain	PH_domain	SWAP70 TRIO ITSN1 SPTBN2 ARHGEF18 OSBP2	1.28e-03	280	80	6	IPR001849
Domain	Dynein_HC_stalk	DNHD1 DYNC2H1	1.59e-03	14	80	2	IPR024743
Domain	Dynein_heavy_dom-2	DNHD1 DYNC2H1	1.59e-03	14	80	2	IPR013602
Domain	DHC_N2	DNHD1 DYNC2H1	1.59e-03	14	80	2	PF08393
Domain	MT	DNHD1 DYNC2H1	1.59e-03	14	80	2	PF12777
Domain	zf-H2C2_2	ZNF286B ZNF286A	1.59e-03	14	80	2	PF13465
Domain	DHC_fam	DNHD1 DYNC2H1	1.83e-03	15	80	2	IPR026983
Domain	Dynein_heavy_dom	DNHD1 DYNC2H1	1.83e-03	15	80	2	IPR004273
Domain	Dynein_heavy	DNHD1 DYNC2H1	1.83e-03	15	80	2	PF03028
Domain	DH_1	TRIO ITSN1 ARHGEF18	2.50e-03	63	80	3	PS00741
Domain	RhoGEF	TRIO ITSN1 ARHGEF18	3.10e-03	68	80	3	SM00325
Domain	EF_hand_dom	TCHH DST SWAP70 ITSN1 MACF1	3.20e-03	232	80	5	IPR002048
Domain	RhoGEF	TRIO ITSN1 ARHGEF18	3.37e-03	70	80	3	PF00621
Domain	DH_2	TRIO ITSN1 ARHGEF18	3.37e-03	70	80	3	PS50010
Domain	DH-domain	TRIO ITSN1 ARHGEF18	3.51e-03	71	80	3	IPR000219
Domain	-	TRIO ITSN1 ARHGEF18	3.51e-03	71	80	3	1.20.900.10
Domain	Prefoldin	CCDC27 CCDC62 MORC4	3.65e-03	72	80	3	IPR009053
Pubmed	Expression of testicular germ cell genes identified by differential display analysis.	ANKRD20A4P ANKRD20A3P ANKRD20A8P ANKRD20A1	2.42e-09	8	86	4	12634303
Pubmed	Cloning and characterization of mouse ACF7, a novel member of the dystonin subfamily of actin binding proteins.	DST MACF1 DMD	5.83e-08	4	86	3	8954775
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	TCAF1 FAM120A SWAP70 DYNC2H1 SPTBN2 ZNF286B MRPS27 ARHGEF18 MACF1 ZNF286A	4.05e-07	493	86	10	15368895
Pubmed	Systematic screening reveals a role for BRCA1 in the response to transcription-associated DNA damage.	KIF20A TONSL TPX2 NOL11 BRCC3 GCC1	1.98e-06	149	86	6	25184681
Pubmed	An Interaction Landscape of Ubiquitin Signaling.	HSPG2 TCAF1 DST USP11 ITSN1 MACF1 OPA3 BRCC3 IKBKB	3.08e-06	481	86	9	28190767
Pubmed	Acf7 (MACF) is an actin and microtubule linker protein whose expression predominates in neural, muscle, and lung development.	DST MACF1	6.04e-06	2	86	2	11002341
Pubmed	NF-κB inhibition rescues cardiac function by remodeling calcium genes in a Duchenne muscular dystrophy model.	DMD IKBKB	6.04e-06	2	86	2	30143619
Pubmed	Intersectin-1 interacts with the golgin GCC88 to couple the actin network and Golgi architecture.	ITSN1 GCC1	6.04e-06	2	86	2	30540523
Pubmed	Intersectin (ITSN) family of scaffolds function as molecular hubs in protein interaction networks.	DST SWAP70 TRIO ITSN1 GCC1	8.57e-06	111	86	5	22558309
Pubmed	HENA, heterogeneous network-based data set for Alzheimer's disease.	DST TRIO ITSN1 MACF1 DMD	1.25e-05	120	86	5	31413325
Pubmed	Long non-coding RNA LINC00337 induces autophagy and chemoresistance to cisplatin in esophageal squamous cell carcinoma cells via upregulation of TPX2 by recruiting E2F4.	TPX2 E2F4	1.81e-05	3	86	2	32239565
Pubmed	The alpha and beta subunits of IkappaB kinase (IKK) mediate TRAF2-dependent IKK recruitment to tumor necrosis factor (TNF) receptor 1 in response to TNF.	TRAF2 IKBKB	1.81e-05	3	86	2	11359906
Pubmed	Expression of the mouse Macf2 gene during inner ear development.	DST MACF1	1.81e-05	3	86	2	12399109
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	DNHD1 DST CEP250 TPX2 MACF1 DMD	2.61e-05	234	86	6	36243803
Pubmed	Differential Modulation of miR-122 Transcription by TGFβ1/BMP6: Implications for Nonresolving Inflammation and Hepatocarcinogenesis.	TRAF2 IKBKB	3.61e-05	4	86	2	37566034
Pubmed	Interaction of the TNFR-receptor associated factor TRAF1 with I-kappa B kinase-2 and TRAF2 indicates a regulatory function for NF-kappa B signaling.	TRAF2 IKBKB	3.61e-05	4	86	2	20856938
Pubmed	Loss of β2-spectrin prevents cardiomyocyte differentiation and heart development.	SPTBN2 DMD	3.61e-05	4	86	2	24064296
Pubmed	Tumor necrosis factor receptor-associated factor 1 gene overexpression in B-cell chronic lymphocytic leukemia: analysis of NF-kappa B/Rel-regulated inhibitors of apoptosis.	TRAF2 IKBKB	6.01e-05	5	86	2	12411322
Pubmed	IKK/NF-kappaB signaling pathway inhibits cell-cycle progression by a novel Rb-independent suppression system for E2F transcription factors.	E2F4 IKBKB	6.01e-05	5	86	2	18542057
Pubmed	Nip2/centrobin may be a substrate of Nek2 that is required for proper spindle assembly during mitosis in early mouse embryos.	CEP250 CNTROB	6.01e-05	5	86	2	19117032
Pubmed	Modulation of the NF-kappa B pathway by virally encoded death effector domains-containing proteins.	TRAF2 IKBKB	6.01e-05	5	86	2	10523854
Pubmed	NF-κB-mediated Pax7 dysregulation in the muscle microenvironment promotes cancer cachexia.	DMD IKBKB	6.01e-05	5	86	2	24084740
Pubmed	RIPK1 Suppresses a TRAF2-Dependent Pathway to Liver Cancer.	TRAF2 IKBKB	6.01e-05	5	86	2	28017612
Pubmed	The NEDD8-activating enzyme inhibitor MLN4924 sensitizes a TNFR1+ subgroup of multiple myeloma cells for TNF-induced cell death.	TRAF2 IKBKB	6.01e-05	5	86	2	31406107
Pubmed	NOL11, implicated in the pathogenesis of North American Indian childhood cirrhosis, is required for pre-rRNA transcription and processing.	NOL11 WDR43	6.01e-05	5	86	2	22916032
Pubmed	TAK1 is critical for IkappaB kinase-mediated activation of the NF-kappaB pathway.	TRAF2 IKBKB	6.01e-05	5	86	2	12547194
Pubmed	Nonstructural 5A protein of hepatitis C virus modulates tumor necrosis factor alpha-stimulated nuclear factor kappa B activation.	TRAF2 IKBKB	6.01e-05	5	86	2	11821416
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	KDM5B TRAF2 DST FAM120A GALNT2 TRIO USP11 ITSN1 SPTBN2 MACF1 BRCC3 TAF12	7.54e-05	1285	86	12	35914814
Pubmed	Interplay of IKK/NF-kappaB signaling in macrophages and myofibers promotes muscle degeneration in Duchenne muscular dystrophy.	DMD IKBKB	9.01e-05	6	86	2	17380205
Pubmed	TNF inhibits Notch-1 in skeletal muscle cells by Ezh2 and DNA methylation mediated repression: implications in duchenne muscular dystrophy.	DMD IKBKB	9.01e-05	6	86	2	20814569
Pubmed	A role for IkappaB kinase 2 in bipolar spindle assembly.	TPX2 IKBKB	9.01e-05	6	86	2	17939994
Pubmed	TRIM25 Promotes TNF-α-Induced NF-κB Activation through Potentiating the K63-Linked Ubiquitination of TRAF2.	TRAF2 IKBKB	9.01e-05	6	86	2	32024699
Pubmed	Deactivation of the kinase IKK by CUEDC2 through recruitment of the phosphatase PP1.	TRAF2 IKBKB	9.01e-05	6	86	2	18362886
Pubmed	PKC phosphorylation of TRAF2 mediates IKKalpha/beta recruitment and K63-linked polyubiquitination.	TRAF2 IKBKB	9.01e-05	6	86	2	19150425
Pubmed	Activation of the Ikappa B kinases by RIP via IKKgamma /NEMO-mediated oligomerization.	TRAF2 IKBKB	9.01e-05	6	86	2	10980203
Pubmed	HIV-1 Nef interacts with HCV Core, recruits TRAF2, TRAF5 and TRAF6, and stimulates HIV-1 replication in macrophages.	TRAF2 IKBKB	1.26e-04	7	86	2	23774506
Pubmed	Tumor necrosis factor-alpha-induced IKK phosphorylation of NF-kappaB p65 on serine 536 is mediated through the TRAF2, TRAF5, and TAK1 signaling pathway.	TRAF2 IKBKB	1.26e-04	7	86	2	12842894
Pubmed	K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors.	PARP10 TRAF2 TCAF1 TPRG1L USP11 ITSN1 BRCC3 IKBKB	1.28e-04	604	86	8	38803224
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	KIF20A KDM5B FAM120A TPX2 MORC4 CNTROB WDR43	1.67e-04	469	86	7	27634302
Pubmed	TRUSS, a novel tumor necrosis factor receptor 1 scaffolding protein that mediates activation of the transcription factor NF-kappaB.	TRAF2 IKBKB	1.68e-04	8	86	2	14585990
Pubmed	Loss of short dystrophin isoform Dp71 in olfactory ensheathing cells causes vomeronasal nerve defasciculation in mouse olfactory system.	HSPG2 DMD	1.68e-04	8	86	2	18586242
Pubmed	Sublethal necroptosis signaling promotes inflammation and liver cancer.	TRAF2 IKBKB	1.68e-04	8	86	2	37329888
Pubmed	Association of beta-arrestin and TRAF6 negatively regulates Toll-like receptor-interleukin 1 receptor signaling.	TRAF2 IKBKB	1.68e-04	8	86	2	16378096
Pubmed	Effects of the NIK aly mutation on NF-kappaB activation by the Epstein-Barr virus latent infection membrane protein, lymphotoxin beta receptor, and CD40.	TRAF2 IKBKB	1.68e-04	8	86	2	11278268
Pubmed	Competition between TRAF2 and TRAF6 regulates NF-kappaB activation in human B lymphocytes.	TRAF2 IKBKB	2.15e-04	9	86	2	20449947
Pubmed	Lack of interaction between NEMO and SHARPIN impairs linear ubiquitination and NF-κB activation and leads to incontinentia pigmenti.	TRAF2 IKBKB	2.15e-04	9	86	2	28249776
Pubmed	Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO.	TRAF2 IKBKB	2.15e-04	9	86	2	16603398
Pubmed	An Internally Translated MAVS Variant Exposes Its Amino-terminal TRAF-Binding Motifs to Deregulate Interferon Induction.	TRAF2 IKBKB	2.15e-04	9	86	2	26221961
Pubmed	Wnt signaling specifies and patterns intestinal endoderm.	ANPEP XPNPEP2	2.15e-04	9	86	2	21854845
Pubmed	Kelch-like Protein 21 (KLHL21) Targets IκB Kinase-β to Regulate Nuclear Factor κ-Light Chain Enhancer of Activated B Cells (NF-κB) Signaling Negatively.	TRAF2 IKBKB	2.15e-04	9	86	2	27387502
Pubmed	IKKε-mediated tumorigenesis requires K63-linked polyubiquitination by a cIAP1/cIAP2/TRAF2 E3 ubiquitin ligase complex.	TRAF2 IKBKB	2.15e-04	9	86	2	23453969
Pubmed	Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activation.	TRAF2 IKBKB	2.15e-04	9	86	2	25636800
Pubmed	Impaired Spermatogenesis, Muscle, and Erythrocyte Function in U12 Intron Splicing-Defective Zrsr1 Mutant Mice.	ZNF286B HCCS ZNF286A	2.19e-04	47	86	3	29617656
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	DST SWAP70 SPTBN2 MACF1	3.12e-04	130	86	4	12421765
Pubmed	DNA sequence and analysis of human chromosome 9.	FAM120A ANKRD20A4P CARD9 ANKRD20A2P ANKRD20A3P ANKRD20A1	3.20e-04	370	86	6	15164053
Pubmed	The germinal center kinase TNIK is required for canonical NF-κB and JNK signaling in B-cells by the EBV oncoprotein LMP1 and the CD40 receptor.	TRAF2 IKBKB	3.28e-04	11	86	2	22904686
Pubmed	IκB kinase ε phosphorylates TRAF2 to promote mammary epithelial cell transformation.	TRAF2 IKBKB	3.28e-04	11	86	2	23007157
Pubmed	Genetic variation in tumor necrosis factor and the nuclear factor-kappaB canonical pathway and risk of non-Hodgkin's lymphoma.	TRAF2 IKBKB	3.28e-04	11	86	2	18990758
Pubmed	The role of microtubule actin cross-linking factor 1 (MACF1) in the Wnt signaling pathway.	DST MACF1	3.28e-04	11	86	2	16815997
Pubmed	Requirement of tumor necrosis factor receptor-associated factor (TRAF)6 in interleukin 17 signal transduction.	TRAF2 IKBKB	3.28e-04	11	86	2	10748240
Pubmed	Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain.	TRAF2 IKBKB	3.28e-04	11	86	2	11057907
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	TRAF2 DST FAM120A GALNT2 SWAP70 TRIO TPX2 MACF1 SEC63 IKBKB HCCS	3.51e-04	1297	86	11	33545068
Pubmed	Tumour necrosis factor signalling in health and disease.	TRAF2 IKBKB	3.93e-04	12	86	2	30755793
Pubmed	HOIL-1L interacting protein (HOIP) as an NF-kappaB regulating component of the CD40 signaling complex.	TRAF2 IKBKB	4.63e-04	13	86	2	20614026
Pubmed	Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism.	TRAF2 SWAP70 CARD9 GCC1 TRIM23 NPAS2	4.96e-04	402	86	6	24722188
Pubmed	Deletion of astroglial connexins weakens the blood-brain barrier.	HSPG2 DMD	5.39e-04	14	86	2	22472609
Pubmed	The cell proliferation antigen Ki-67 organises heterochromatin.	DST HAUS5 TPX2 MRPS27 ARHGEF18 WDR48	5.50e-04	410	86	6	26949251
Pubmed	Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.	DST TRIO MACF1 DMD	5.50e-04	151	86	4	17043677
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	DYNC2H1 TPX2 DMD SEC63 TAF12 CNTROB HCCS CCDC39	5.64e-04	754	86	8	35906200
Pubmed	The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes.	TRAF2 IKBKB	6.21e-04	15	86	2	15125833
Pubmed	The kinase IKKα inhibits activation of the transcription factor NF-κB by phosphorylating the regulatory molecule TAX1BP1.	TRAF2 IKBKB	6.21e-04	15	86	2	21765415
Pubmed	Essential cytoplasmic translocation of a cytokine receptor-assembled signaling complex.	TRAF2 IKBKB	6.21e-04	15	86	2	18635759
Pubmed	Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction.	TRAF2 IKBKB	6.21e-04	15	86	2	20005846
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	DST TRIO MACF1 DMD SEC63 WDR48	6.31e-04	421	86	6	36976175
Pubmed	Functional proteomics mapping of a human signaling pathway.	HSPG2 DST ITSN1 CEP250 MACF1 ASXL2 MORC4	6.66e-04	591	86	7	15231748
Pubmed	Lung Epithelial Cells Coordinate Innate Lymphocytes and Immunity against Pulmonary Fungal Infection.	CARD9 IKBKB	7.09e-04	16	86	2	29576482
Pubmed	The tyrosine kinase Syk regulates TPL2 activation signals.	TRAF2 IKBKB	7.09e-04	16	86	2	16291755
Pubmed	Human transcription factor protein interaction networks.	HSPG2 DST FAM120A USP11 RAB1C TPX2 MRPS27 ASXL2 MORC4 TAF12 WDR48	7.86e-04	1429	86	11	35140242
Pubmed	Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region.	ZFP90 CARD9	8.02e-04	17	86	2	19915572
Pubmed	Differential regulation of node formation, nodal ciliogenesis and cilia positioning by Noto and Foxj1.	TEKT2 DYNC2H1	8.02e-04	17	86	2	22357932
Pubmed	Comprehensive analysis of low-abundance proteins in human urinary exosomes using peptide ligand library technology, peptide OFFGEL fractionation and nanoHPLC-chip-MS/MS.	ANPEP XPNPEP2	8.02e-04	17	86	2	21082674
Pubmed	Misregulation of an Activity-Dependent Splicing Network as a Common Mechanism Underlying Autism Spectrum Disorders.	DYNC2H1 ITSN1	9.01e-04	18	86	2	27984743
Pubmed	A protein interaction landscape of breast cancer.	DST TRIO SPTBN2 MACF1 BRCC3 E2F4 WDR48	1.00e-03	634	86	7	34591612
Pubmed	The DNA sequence and biological annotation of human chromosome 1.	GREM2 CCDC27 ANKRD35 TEKT2 GALNT2 TPRG1L MACF1 TAF12 TTLL7	1.02e-03	1031	86	9	16710414
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	KIF20A DST HAUS5 TONSL TPX2 XRCC4 CNTROB	1.11e-03	645	86	7	25281560
Pubmed	Analysis of interaction partners for eukaryotic translation elongation factor 1A M-domain by functional proteomics.	DST MACF1	1.12e-03	20	86	2	21689717
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	DST FAM120A USP11 SPTBN2 NOL11 MACF1 WDR43	1.19e-03	653	86	7	22586326
Pubmed	Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.	DNHD1 DST DYNC2H1 DMD	1.22e-03	187	86	4	26460568
Pubmed	Interactome of vertebrate GAF/ThPOK reveals its diverse functions in gene regulation and DNA repair.	TFEC FAM120A MRPS27 FHIP1B CCDC39	1.23e-03	321	86	5	32098917
Pubmed	DOT1L regulates dystrophin expression and is critical for cardiac function.	HSPG2 DMD	1.23e-03	21	86	2	21289070
Pubmed	A human MAP kinase interactome.	DST ITSN1 CEP250 SPTBN2 MACF1 DMD	1.32e-03	486	86	6	20936779
Pubmed	Co-ordinated control of the ADP-heptose/ALPK1 signalling network by the E3 ligases TRAF6, TRAF2/c-IAP1 and LUBAC.	TRAF2 IKBKB	1.35e-03	22	86	2	36098982
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	DST TRIO ITSN1 MACF1 CNTROB	1.42e-03	332	86	5	37433992
Pubmed	The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.	DST ARHGEF18 MACF1 DMD	1.48e-03	197	86	4	20811636
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	HSPG2 DST FAM120A TRIO USP11 MACF1	1.48e-03	497	86	6	23414517
Pubmed	Tagging genes with cassette-exchange sites.	KDM5B TRAF2 TPX2 MACF1 WDR43	1.48e-03	335	86	5	15741177
Pubmed	USP37 is a SNAI1 deubiquitinase.	USP11 BRCC3	1.61e-03	24	86	2	31911859
Pubmed	Conditional deletion of beta1-integrin in astroglia causes partial reactive gliosis.	HSPG2 DMD	1.75e-03	25	86	2	19373938
Pubmed	Cilia gene mutations cause atrioventricular septal defects by multiple mechanisms.	DYNC2H1 CCDC39	1.75e-03	25	86	2	27340223
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	KIF20A TRAF2 TCHH FAM120A USP11 HAUS5 MACF1 TAF12 WDR48	1.76e-03	1116	86	9	31753913
Interaction	ANKRD20A4P interactions	ANKRD20A4P ANKRD20A2P ANKRD20A1	1.29e-06	6	82	3	int:ANKRD20A4P
Interaction	ANKRD20A2P interactions	ANKRD20A4P ANKRD20A2P ANKRD20A1	2.25e-06	7	82	3	int:ANKRD20A2P
Interaction	ANKRD20A1 interactions	ANKRD20A4P ANKRD20A2P ANKRD20A1	1.05e-05	11	82	3	int:ANKRD20A1
Interaction	PPIA interactions	KIF20A DST TRIO DYNC2H1 USP11 SPEF2 ITSN1 MACF1 E2F4 ASXL2 DMD FAM186B TRIM23 SMTN	1.27e-05	888	82	14	int:PPIA
Cytoband	1p36.32	CCDC27 TPRG1L	8.55e-04	23	86	2	1p36.32
Cytoband	8q24.3	PARP10 CCDC166 TONSL	1.28e-03	113	86	3	8q24.3
Cytoband	9p12	ANKRD20A2P ANKRD20A3P	1.36e-03	29	86	2	9p12
Cytoband	Xq25	XPNPEP2 ENOX2	2.71e-03	41	86	2	Xq25
GeneFamily	Ankyrin repeat domain containing	ANKRD35 ANKRD20A4P TONSL ANKRD20A2P ANKRD20A3P ANKRD20A1	9.05e-05	242	55	6	403
GeneFamily	EF-hand domain containing\|Plakins	DST MACF1	2.51e-04	8	55	2	939
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	SWAP70 ITSN1 SPTBN2 ARHGEF18 OSBP2	4.01e-04	206	55	5	682
GeneFamily	EF-hand domain containing	TCHH DST SWAP70 ITSN1 MACF1	5.30e-04	219	55	5	863
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	TRIO ITSN1 ARHGEF18	1.06e-03	66	55	3	722
GeneFamily	Aminopeptidases\|CD molecules	ANPEP XPNPEP2	1.20e-03	17	55	2	104
ToppCell	COPD-Myeloid-cDC1\|World / Disease state, Lineage and Cell class	DST ANKRD20A4P ANKRD20A2P OSBP2 ANKRD20A3P ANKRD20A8P ANKRD20A1	6.44e-08	184	85	7	42d7ce104cd7bcb83fbbbd0e7d3267ad07edfa94
ToppCell	Control-Myeloid-cDC1\|Myeloid / Disease state, Lineage and Cell class	TMEM156 ANKRD20A4P ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A1	1.44e-06	184	85	6	c6affa0b12510363258f65e46bf2d47bf4a8e75f
ToppCell	COPD-Myeloid-cDC1\|Myeloid / Disease state, Lineage and Cell class	ANKRD20A4P ANKRD20A2P OSBP2 ANKRD20A3P ANKRD20A8P ANKRD20A1	1.79e-06	191	85	6	3480e6d27dd4291765bbbb2acdb6a2e4f02c8085
ToppCell	COPD-Myeloid-cDC1\|COPD / Disease state, Lineage and Cell class	ANKRD20A4P ANKRD20A2P OSBP2 ANKRD20A3P ANKRD20A8P ANKRD20A1	1.85e-06	192	85	6	bd3d00b094d92463b06023361a71240851a542b8
ToppCell	TCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma-Intrahepatic\|TCGA-Bile_Duct / Sample_Type by Project: Shred V9	TRIO MRPS27 NOL11 XRCC4 SUV39H2 TRIM23	2.34e-06	200	85	6	1fa8422fd820d21e285a7e7c4c6fbd8b7277d2af
ToppCell	AT2_cells-IPF_02\|World / lung cells shred on cell class, cell subclass, sample id	HSPG2 ANKRD20A4P SPTBN2 ANKRD20A2P ANKRD20A3P	5.27e-06	131	85	5	ff4e618bd944f852bbd34438f740187aca82460f
ToppCell	systemic_lupus_erythematosus-managed-Lymphocytic_B-plasmablast-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	TMEM156 HSPG2 TPX2 GPR55 TTLL7	2.14e-05	175	85	5	89bf89466191da14896ed8928027f5b911436c22
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_A2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	TRAF2 DST TRIM23 TTLL7 SMTN	2.14e-05	175	85	5	334fad1a147de6c007cec5089c02c35cf3220f1b
ToppCell	wk_08-11-Mesenchymal-Myofibro_&_SMC-ACTC+_SMC\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	GREM2 ANKRD20A4P ANKRD20A3P ANKRD20A1 SMTN	2.73e-05	184	85	5	39168ca2bbf1369c9fe87c67f0aaff5e3cd03151
ToppCell	NS-critical-d_16-33-Epithelial-Ciliated\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TEKT2 IQCA1 DYNC2H1 SPEF2 CCDC39	2.87e-05	186	85	5	76033438426d8f9c72cd6691a7baf92104c9f03d
ToppCell	IPF-Myeloid-cDC1\|World / Disease state, Lineage and Cell class	ANKRD20A4P ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A1	2.87e-05	186	85	5	962c2dada19185628ead77c32fcb07fa95114247
ToppCell	Control-Myeloid-cDC1\|Control / Disease state, Lineage and Cell class	ANKRD20A4P ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A1	2.87e-05	186	85	5	b05c394aa3573ba855abc3066739ca193883b0c3
ToppCell	3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Cycling_pre-Myeloid-2\|lymph-node_spleen / Manually curated celltypes from each tissue	ANPEP ITSN1 BRCC3 SUV39H2 SMTN	2.95e-05	187	85	5	3c10b8501226c69d71bcd99dc1c064a3c2154f87
ToppCell	Control-Lymphoid-B\|Lymphoid / Disease state, Lineage and Cell class	TMEM156 TFEC SWAP70 TRIO ARHGEF18	2.95e-05	187	85	5	4e64be635f445276e71f2937f33f041c3a4204ab
ToppCell	(04)_Pre-ciliated-(3)_72hpi\|(04)_Pre-ciliated / shred by cell type and Timepoint	EHBP1L1 CROCC2 TPX2 CNTROB CCDC39	3.02e-05	188	85	5	f911dc61b008b60aaa2a1e9354085f480a669e2c
ToppCell	IPF-Myeloid-cDC1\|Myeloid / Disease state, Lineage and Cell class	ANKRD20A4P ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A1	3.02e-05	188	85	5	47bb6caf84f70a1cda7d09803afdfd5182772e66
ToppCell	Epithelial-Epithelial-D_(Ciliated)\|Epithelial / shred on cell class and cell subclass (v4)	TEKT2 IQCA1 DYNC2H1 SPEF2 CCDC39	3.02e-05	188	85	5	8f30535a32968a81a304315a49c0d90a77d36948
ToppCell	IPF-Myeloid-cDC1\|IPF / Disease state, Lineage and Cell class	ANKRD20A4P ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A1	3.02e-05	188	85	5	2331a2bae1383820d598e93aa86c75b101069bac
ToppCell	E18.5-Epithelial-Epithelial_Airway\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TEKT2 IQCA1 CROCC2 SPEF2 CCDC39	3.18e-05	190	85	5	5c012935ea5e35a2d0d08ea7dc04ffbe3c2a10ac
ToppCell	E18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TEKT2 IQCA1 CROCC2 SPEF2 CCDC39	3.26e-05	191	85	5	acd844b477a069b2dcf07b2998e1b5c87dc0eb94
ToppCell	E16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TEKT2 IQCA1 CROCC2 SPEF2 CCDC39	3.26e-05	191	85	5	1e21de183a9c09cfb6aad3f9b948087fb6bad061
ToppCell	E16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TEKT2 IQCA1 CROCC2 SPEF2 CCDC39	3.26e-05	191	85	5	8688708c9183ebcb200596501dc30cc12073f151
ToppCell	PND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TEKT2 IQCA1 CROCC2 SPEF2 CCDC39	3.26e-05	191	85	5	96483adb97c81208aa513782550acd8a08b63866
ToppCell	E16.5-Epithelial-Epithelial_Airway\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TEKT2 IQCA1 CROCC2 SPEF2 CCDC39	3.34e-05	192	85	5	bb7eb51bc079acacde42d8e55ba06d03eba2ea28
ToppCell	E16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TEKT2 IQCA1 CROCC2 SPEF2 CCDC39	3.34e-05	192	85	5	a50a6279371b3be682e334082637b7ab76b9a6e5
ToppCell	Control-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	TEKT2 DYNC2H1 CROCC2 SPEF2 CCDC39	3.42e-05	193	85	5	0e37d454f3735edd936ee9a5f5f516ac3aad400e
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DST FAM120A DYNC2H1 MACF1 TTLL7	3.60e-05	195	85	5	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	moderate-Epithelial-Ciliated\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	TEKT2 IQCA1 DYNC2H1 SPEF2 CCDC39	3.60e-05	195	85	5	e80f5cdf0b18066b3e6c2f5452e58f101c67932c
ToppCell	BL-critical-LOC-Epithelial-Ciliated\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TEKT2 IQCA1 DYNC2H1 SPEF2 CCDC39	3.60e-05	195	85	5	07a6bcef6af93ed87df455dee624037cb75e011a
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DST FAM120A DYNC2H1 MACF1 TTLL7	3.60e-05	195	85	5	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	critical-Epithelial-Ciliated\|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	TEKT2 IQCA1 DYNC2H1 SPEF2 CCDC39	3.69e-05	196	85	5	27b855c6e1ae44f16db998cf0e81bd686b9cee7e
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DYNC2H1 CROCC2 SPEF2 DMD CCDC39	3.78e-05	197	85	5	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	Parenchymal-NucSeq-Immune_Myeloid-Dendritic_cell-DC_1\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	EHBP1L1 ANKRD20A4P ANPEP ANKRD20A2P ANKRD20A3P	3.87e-05	198	85	5	fa5c15a656d4132950092919600e270f1fd79abf
ToppCell	TCGA-Colorectal-Primary_Tumor\|TCGA-Colorectal / Sample_Type by Project: Shred V9	KIF20A SPTBN2 HAUS5 TPX2 WDR43	3.96e-05	199	85	5	c7d6a8398f2419b726a0461585d1ee0561654e3b
ToppCell	Bronchial-10x5prime-Epithelial-Epi_airway_ciliated-Deuterosomal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	KIF20A TEKT2 CROCC2 TPX2 ANKRD20A3P	3.96e-05	199	85	5	92778939e9d06599c7d06cfd8f4362b97ed0606b
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma\|TCGA-Colorectal / Sample_Type by Project: Shred V9	KIF20A SPTBN2 HAUS5 TPX2 WDR43	3.96e-05	199	85	5	85b3b1ad01368dae4adbc9da7efc148e49992f69
ToppCell	LPS_only-Mesenchymal_myocytic-Myofibroblastic\|LPS_only / Treatment groups by lineage, cell group, cell type	TCAF1 DST ITSN1 DMD SMTN	4.06e-05	200	85	5	02cae2c296a13ad4cbb53bca7a86d64629d67d66
ToppCell	(53)_Lymphoid_DC\|World / shred on Cell_type and subtype	ITSN1 ANKRD20A2P ANKRD20A3P DMD ANKRD20A1	4.89e-05	208	85	5	30212cfacad94a7cc562a69efa73a31259851515
ToppCell	PBMC-Control-Lymphocyte-B-B_cell-B_intermediate-B_activate-7\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SWAP70 SPTBN2 GPR55 DMD	9.96e-05	126	85	4	518a6e4919981b556ce6b451a91270dba976bc75
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Diffuse-7\|TCGA-Stomach / Sample_Type by Project: Shred V9	ARHGEF18 DMD TTLL7 SMTN	1.30e-04	135	85	4	451e90c154e26ae4f72269d6765e7ef51d67313a
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-myeloid-myeloid_dendritic-myeloid_dendritic_cell\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ANKRD20A4P ANPEP CARD9 ANKRD20A3P	1.90e-04	149	85	4	71d72a6e7b128ee96161e08f6a0d77be925e73a1
ToppCell	PND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TEKT2 CROCC2 SPEF2 CCDC39	2.00e-04	151	85	4	e335dad89e0a44cdd302b9653154ba5d1ee5fe1a
ToppCell	PND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TEKT2 CROCC2 SPEF2 CCDC39	2.00e-04	151	85	4	633ed52dd3b4cf1e87432cf0a1ca187d7b204e83
ToppCell	Severe-B_naive-1\|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)	TCAF1 SWAP70 ARHGEF18 MACF1	2.43e-04	159	85	4	2881b054bbeb479221ee3c38bbd9b0815b123579
ToppCell	10x5'v1-week_17-19-Hematopoietic-HSC/MPP_and_pro\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	TMEM156 KDM5B GALNT2 IQCA1	2.68e-04	163	85	4	edca1d1a345109dbdeb7ee5464faefab1993fdb2
ToppCell	Ciliated_cells-B-Donor_03\|World / lung cells shred on cell class, cell subclass, sample id	DYNC2H1 SPEF2 CCDC39 TTLL7	2.74e-04	164	85	4	fd30c55d0d75ef8b9396435d836187168095152b
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW16-Mesenchymal-Cilia-bearing_cell\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	FAM120A SPEF2 CCDC62 TMEM191C	2.74e-04	164	85	4	346e1530b4bf30adbcb2f7d64fdfb4cd8df69d7f
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_B-B_naive-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	TMEM156 SWAP70 SPTBN2 DMD	2.80e-04	165	85	4	8003fd2aa3f5c9d0e99054af4ad2d79a4a3c4829
ToppCell	PND01-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF20A TFEC TPX2 GPR55	3.00e-04	168	85	4	52fd65024af8683db11d931f7563cbe8eb815d1c
ToppCell	PND07-Epithelial-Epithelial_Airway-Basal-Basal-Basal_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF20A DST SPTBN2 TPX2	3.00e-04	168	85	4	f150beee37e0252951a88adcd9e3f0a22e5cfdd9
ToppCell	10x5'v1-week_17-19-Hematopoietic-HSC/MPP_and_pro-ELP\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	TMEM156 KDM5B GALNT2 XPNPEP2	3.14e-04	170	85	4	a50e558d0b38100ccbdccb90647fe93e85bffd86
ToppCell	droplet-Liver-HEPATOCYTES-1m-Lymphocytic-NK/T\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PARP10 CCDC166 GIMAP5 CEP250	3.21e-04	171	85	4	2e7cc311005958af52f39ca6c310c85b43a85aaf
ToppCell	E16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TEKT2 SPEF2 OSBP2 CCDC39	3.21e-04	171	85	4	4f2a83d8091f1fd29542d2e5add57fd482e921b5
ToppCell	droplet-Liver-HEPATOCYTES-1m-Lymphocytic-NK_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PARP10 CCDC166 GIMAP5 CEP250	3.21e-04	171	85	4	4b599f953c8e5b947b2c8bbbf7fe6f9dc388e336
ToppCell	wk_08-11-Epithelial-Proximal_epithelial-Deuterosomal\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	CCDC27 TEKT2 CROCC2 CCDC39	3.28e-04	172	85	4	08ad76412c9cc3504141797b44b88478ced87476
ToppCell	Ciliated_cells-B-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	IQCA1 DYNC2H1 SPEF2 CCDC39	3.28e-04	172	85	4	187ae91148d293537afc77e10da2b64302322224
ToppCell	facs-Large_Intestine-Proximal-24m-Epithelial-secretory_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFP90 CCDC166 USP11 SUV39H2	3.35e-04	173	85	4	766e712e4db440468a32971459c1d3354add611f
ToppCell	facs-Large_Intestine-Proximal-24m-Epithelial-Reg4/cKit+_deep_crypt_secretory_cells_(Distal)\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFP90 CCDC166 USP11 SUV39H2	3.35e-04	173	85	4	40ef91afb366e87b5ba2951d2578ebfe04d042c0
ToppCell	droplet-Lung-1m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ZFP90 ANPEP PHF11 ENOX2	3.50e-04	175	85	4	1b910c08d2bfbcc77431ee66103e63a11a9d39fe
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF20A GALNT2 TPX2 SUV39H2	3.50e-04	175	85	4	15c69dd5635c9251c535f1e22467712e9667ae92
ToppCell	Ciliated_cells-A-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	TEKT2 CROCC2 SPEF2 CCDC39	3.58e-04	176	85	4	1c364155f46b9a7c995bdc2cc2333c437cd90f5b
ToppCell	NS-critical-d_0-4-Epithelial-Ciliated\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TEKT2 DYNC2H1 SPEF2 CCDC39	3.58e-04	176	85	4	b794275fdd757b8fa2108e3c867f23da2649146d
ToppCell	3'_v3-blood-Mast-Mast_cell_granulo-myelo\|blood / Manually curated celltypes from each tissue	HSPG2 TRIO TTLL7 SMTN	3.58e-04	176	85	4	d421b6b8e13894dbcf29548c0a6516c3dee8f9b1
ToppCell	Healthy-RBC\|World / disease group, cell group and cell class	KIF20A TEKT2 WFIKKN1 OSBP2	3.66e-04	177	85	4	2ce41e37fa7139c7bd2b464bd86c5601dc501515
ToppCell	Healthy-RBC\|Healthy / disease group, cell group and cell class	KIF20A TEKT2 WFIKKN1 OSBP2	3.66e-04	177	85	4	945d72ab52efa9a9468daace9f9ec676a891d963
ToppCell	Tracheal-NucSeq-Immune_Myeloid-Dendritic_cell-DC_plasmacytoid\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TFEC TPRG1L CARD9	3.68e-04	73	85	3	582faedb369a099d0acf1565413e6b3ca2cfc564
ToppCell	T_cells-ISG-high_CD4+_T_cells\|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis	GREM2 PARP10 GIMAP5 PHF11	3.82e-04	179	85	4	af35ef8a7768cee0c2af0590e5bec35cee6a4714
ToppCell	10x5'-Lung-Lymphocytic_B_plasma-Plasmablasts\|Lung / Manually curated celltypes from each tissue	KIF20A TPX2 MRPS27 NOL11	3.82e-04	179	85	4	3fa75eec3e86fd1797eaa33362257df7f9b2a0bf
ToppCell	PCW_13-14-Hematologic_Myeloid-Hem_Myeloid_dendritic-im_conventional_dendritic_(19)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	TMEM156 TFEC ANPEP ANKRD20A1	3.82e-04	179	85	4	9fc44637c9a7551fd47b8533e45a9c199e164a95
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-Alveolar_macrophage_proliferating_L.1.0.7.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KIF20A CCDC62 TPX2 SUV39H2	3.98e-04	181	85	4	73b1b59810f60e3e39ca1d5073a5a0d4f5377e6e
ToppCell	10x5'-bone_marrow-Mast-Mast_cell_lympho\|bone_marrow / Manually curated celltypes from each tissue	HSPG2 CNTROB SUV39H2 TTLL7	3.98e-04	181	85	4	56fa77ae31f3b7de6e441a439c33a11353b6573a
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GREM2 DST MACF1 SMTN	3.98e-04	181	85	4	beb2771820956be8b190c0088ae3c4efdb53c897
ToppCell	droplet-Lung-immune-endo-depleted-3m-Lymphocytic-T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF20A TMEM191C TPX2 CNTROB	4.06e-04	182	85	4	3948422707d6d5e021bcd7158e2eb69143613f62
ToppCell	Ciliated_cells-B-SSc-ILD_02\|World / lung cells shred on cell class, cell subclass, sample id	TEKT2 CROCC2 SPEF2 CCDC39	4.06e-04	182	85	4	e44c4810dc7d51a76b86d7623f8e4c4d8b4bf2fc
ToppCell	droplet-Lung-immune-endo-depleted-3m-Lymphocytic-Proliferating_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF20A TMEM191C TPX2 CNTROB	4.06e-04	182	85	4	fe46819c153a81911864473badc794f243705f98
ToppCell	Ciliated_cells-B-Donor_04\|World / lung cells shred on cell class, cell subclass, sample id	DYNC2H1 CROCC2 SPEF2 CCDC39	4.06e-04	182	85	4	e93968f800bfeb258e4e834fc8bf92d1cb72cd73
ToppCell	18-Airway-Epithelial-Multiciliated_precursor\|Airway / Age, Tissue, Lineage and Cell class	TEKT2 ANKRD20A4P MYRFL ANKRD20A1	4.15e-04	183	85	4	a75cda2131755931117c387f2e0ae3394efa8e80
ToppCell	droplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HSPG2 TCAF1 DMD MORC4	4.15e-04	183	85	4	351d575339038bd4a66f408da518c567444208e8
ToppCell	BAL-Severe-Myeloid-cDC-cDC-cDC_11\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	DST ANKRD20A3P DMD ANKRD20A1	4.23e-04	184	85	4	667846c422cfa27e949a24844a305df859cb6760
ToppCell	P07-Epithelial-airway_epithelial_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	TEKT2 IQCA1 SPEF2 CCDC39	4.23e-04	184	85	4	a5e7af3392e9d6ddad0397f1eeb6b91ed1107cc2
ToppCell	P07-Epithelial-airway_epithelial_cell-club_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	TEKT2 IQCA1 SPEF2 CCDC39	4.23e-04	184	85	4	ab469b9e06212462cbe2e4db8775c6778db855e6
ToppCell	E18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TEKT2 IQCA1 SPEF2 CCDC39	4.23e-04	184	85	4	797b6a6d6f6aafae98f75ca8bffe8263f8d3ff9b
ToppCell	3'-Child09-12-SmallIntestine-Mesenchymal-myocytic\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GREM2 DMD TTLL7 SMTN	4.23e-04	184	85	4	5cfc19ffb9f074bdf0d81c86e212a708ec141631
ToppCell	E18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TEKT2 IQCA1 SPEF2 CCDC39	4.23e-04	184	85	4	77d5b60a20b277f589b18f7a131142a7ef2dac17
ToppCell	Ciliated_cells-B-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	TEKT2 DYNC2H1 SPEF2 CCDC39	4.32e-04	185	85	4	f012c243343e1d1956db19b34d062e9b13de2b2a
ToppCell	368C-Myeloid-Dendritic-cDC_proliferating_1\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	KIF20A TMEM156 TPX2 PET117	4.41e-04	186	85	4	799903b68bc6f6205d004b44c603424b0d5f7c32
ToppCell	Control-Myeloid-cDC1\|World / Disease state, Lineage and Cell class	ANKRD20A4P ANKRD20A2P ANKRD20A3P ANKRD20A1	4.41e-04	186	85	4	3de803dee3ef10eb85a2b47d3f93385214e5b0ff
ToppCell	PCW_07-8.5-Hematologic_ErythroMegGranulo-Hem_ErythroMeg-erythro\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	EHBP1L1 OSBP2 ANKRD20A8P ANKRD20A1	4.41e-04	186	85	4	6078aa16261554c7fd41137b8de1362d15b30490
ToppCell	10x5'-Liver-Myeloid_Dendritic-DC1\|Liver / Manually curated celltypes from each tissue	DST ANPEP ANKRD20A2P DMD	4.41e-04	186	85	4	e823529ffd06352c6bdec102f221fdf27f7c7369
ToppCell	droplet-Tongue-nan-24m-Epithelial-parabasal\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCHH ANPEP IL36A TTLL7	4.41e-04	186	85	4	18c06041c6c8a0ebac17b3c8aaebd67e652d315a
ToppCell	PND14-Epithelial-Epithelial_Airway\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TEKT2 IQCA1 SPEF2 CCDC39	4.50e-04	187	85	4	1399c703505211c510b3f14c7a2aa9930566c473
ToppCell	facs-Lung-EPCAM-3m-Epithelial-Ciliated_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TEKT2 IQCA1 SPEF2 CCDC39	4.50e-04	187	85	4	04dba2ed09ee4180830bdf0191921696697ea234
ToppCell	tumor_Lung-Epithelial_cells-tS3\|Epithelial_cells / Location, Cell class and cell subclass	TEKT2 SPEF2 CCDC39 TTLL7	4.50e-04	187	85	4	3cea677279e71fdb9879530dea10a5e6393beacd
ToppCell	COVID-19-Fibroblasts-Airway_smooth_muscle\|COVID-19 / group, cell type (main and fine annotations)	DST DMD TTLL7 SMTN	4.50e-04	187	85	4	464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCell	facs-Lung-EPCAM-18m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TEKT2 IQCA1 SPEF2 CCDC39	4.50e-04	187	85	4	051b8c07d7489ce7576f6c57ce7008767ef76869
ToppCell	facs-Lung-EPCAM-18m-Epithelial-Ciliated_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TEKT2 IQCA1 SPEF2 CCDC39	4.50e-04	187	85	4	888856cde7a69ea2f14d590597e25b1af6383c51
ToppCell	wk_08-11-Hematologic-Myeloid-DC1\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	TMEM156 ANPEP GPR55 ANKRD20A1	4.50e-04	187	85	4	2907cc0b8789c5e1468917caa21fa0feb025305e
ToppCell	facs-Lung-EPCAM-3m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TEKT2 IQCA1 SPEF2 CCDC39	4.50e-04	187	85	4	805dafe22f835ece4dd091d8030d0a63b52a48dd
ToppCell	Monocytes-M2-like_CD16+_macrophages\|Monocytes / Immune cells in Kidney/Urine in Lupus Nephritis	TCHH GIMAP5 ITSN1 IKBKB	4.50e-04	187	85	4	59e31c51183ed4c9a3d0792c8005ea3a12b28dfa
ToppCell	IPF-Lymphoid-B\|Lymphoid / Disease state, Lineage and Cell class	TMEM156 SWAP70 TRIO ARHGEF18	4.50e-04	187	85	4	af1327559f7e01bec070881cae52834917c3da65
Disease	retinal degeneration (biomarker_via_orthology)	CARD9 DMD	2.43e-03	28	77	2	DOID:8466 (biomarker_via_orthology)
Disease	cholesteryl esters:total lipids ratio, intermediate density lipoprotein measurement	GALNT2 MACF1 OPA3	2.51e-03	103	77	3	EFO_0008595, EFO_0020944

Protein segments in the cluster

Peptide	Gene	Start	Entry
WLENQQGNQERHLRE	ZNF286A	161	Q9HBT8
HLQRENAWLVQQLDD	ANKRD20A1	736	Q5TYW2
LEKLQSQLRHEQQRW	ARHGEF18	1056	Q6ZSZ5
EQQRWERERQWQHQE	ARHGEF18	1066	Q6ZSZ5
HLQRENAWLVQQLDD	ANKRD20A8P	736	Q5CZ79
HQQQLLSWEEDRQKV	CCDC62	51	Q6P9F0
HLQRENAWLVQQLDD	ANKRD20A4P	736	Q4UJ75
EENWRKIQTQLQRDH	ANPEP	636	P15144
QVAVERWNRHDQKLL	ANKRD35	11	Q8N283
IRIHNQNNEQAWKEI	HCCS	151	P53701
EQEHQEKLRQWNLED	FAM186B	511	Q8IYM0
WDEVQEHLQNRRQQL	DMD	2561	P11532
DRINQVWQNENERIH	DNHD1	1136	Q96M86
QVLEEDWRQALRDHQ	CARD9	281	Q9H257
VDIKENLQDQIRHWF	IQCA1	291	Q86XH1
WEKRPRVTENRQHQQ	ASXL2	581	Q76L83
LQEQVELDQNHLQRW	CCDC27	536	Q2M243
ELDQNHLQRWKQLQE	CCDC27	541	Q2M243
IHNERQELIKQWENT	CCDC39	216	Q9UFE4
QWLQEIDRHASENVN	RAB1C	101	Q92928
WKTRNQELEDNVHIS	HSPG2	3056	P98160
VHDNKVLRIWNNEDV	NOL11	81	Q9H8H0
RWQQEELHKIQEQLC	NPAS2	521	Q99743
HLQRENAWLVQQLDD	ANKRD20A2P	736	Q5SQ80
KNHWSQVVRILERQG	FHIP1B	41	Q8N612
RWHNQETGEQIAIKQ	IKBKB	31	O14920
KEKADQLVERWQNVH	DST	1261	Q03001
WQNVHVQIDNRLRDL	DST	1271	Q03001
RFEEVLAWAKQHQQR	DST	7011	Q03001
VWCKQAEEIRNIHND	ENOX2	361	Q16206
TRHDQCQRKQWRVDL	GALNT2	121	Q10471
AQQRHKEEEQRAAWN	OPA3	106	Q9H6K4
IEDWQKTSAQQHREQ	EHBP1L1	1451	Q8N3D4
VQRQSEEKEFHQRRW	MYRFL	726	Q96LU7
IERTVNWQHRAQQLL	KDM5B	1256	Q9UGL1
HEWVKRQGNERQTAQ	FAM120A	106	Q9NZB2
AKQQRILHWRQLVEE	HAUS5	381	O94927
NSERWQHQIKEVLAS	GREM2	41	Q9H772
RRDHTQDWVQQKACI	GPR55	211	Q9Y2T6
HSRKWQRALQYEQEQ	OSBP2	381	Q969R2
QEKGSQLQERWHRVI	MACF1	1246	Q9UPN3
QLQERWHRVIAQLEI	MACF1	1251	Q9UPN3
EVLTWAKQHQQRLET	MACF1	6861	Q9UPN3
WQVEKHKQELRENES	GIMAP5	251	Q96F15
INQLDREHKRWNAQV	DYNC2H1	3176	Q8NCM8
HLQRENAWLVQQLDD	ANKRD20A3P	736	Q5VUR7
DWKQELARLQQLHRQ	GCC1	551	Q96CN9
QDINHRVWVLQDQTL	IL36A	16	Q9UHA7
ELQQREQELDQHKVW	E2F4	106	Q16254
KEQLDQEVQWRQQAH	CROCC2	1626	H7BZ55
EQNRVDLAQIHWQRA	CCDC166	96	P0CW27
RRAQERDKQWLEHVQ	ITSN1	651	Q15811
QSWRQRLEHLQQAVA	CEP250	2266	Q9BV73
EEERQTWAQQEHQLK	CNTROB	356	Q8N137
AGVHVKQQWDQQRLR	PET117	21	Q6UWS5
QQWQVAERVLQQEHR	PARP10	221	Q53GL7
QWHLDLVQLIQREQQ	MRPS27	381	Q92552
VLWQNRIFREKQHEE	SPEF2	361	Q9C093
EQHSRQLQEQWEELS	TMEM191B	141	P0C7N4
EQHSRQLQEQWEELS	TMEM191C	141	A6NGB0
VHELGRNQQRQEWEF	TCAF1	756	Q9Y4C2
LEVKDVQLHLERQWN	TAF12	111	Q16514
QKVEELEQERNHWQS	MORC4	791	Q8TE76
NQTIWDEHDNRTRLV	TEKT2	51	Q9UIF3
WLEDRLEQNQQHLQE	BRCC3	286	P46736
LEGQRRVQKWQSHRD	TMEM156	236	Q8N614
KQQEHEVQWLREHLA	TRAF2	231	Q12933
DSIIRIWSVNQHKQD	WDR48	51	Q8TAF3
KDRIVNTQEQLNHRW	SPTBN2	926	O15020
DAQRHVLWARVQLNE	SPEM3	1061	A0A1B0GUW6
QQREQWCSEHLDTQK	KIF20A	601	O95235
ALEQHWQELQLRERA	TONSL	46	Q96HA7
ALQRWQDELNRRKNH	SUV39H2	136	Q9H5I1
HWNNEKERLVLVTEQ	TPRG1L	101	Q5T0D9
NEHLQKENERLLRDW	XRCC4	141	Q13426
LEQRQEPWNVKRHET	ZNF682	56	O95780
AEWQELQQSIQRKER	SEC63	611	Q9UGP8
IHASQQRWQQLKEEI	PHF11	286	Q9UIL8
AVTWEKQSHQRENLI	WFIKKN1	216	Q96NZ8
RAELEKWHLEQQQAI	SWAP70	461	Q9UH65
WLQKEQQRARELEHR	TFEC	191	O14948
AENEELHQLWRKLTQ	TTC37	151	Q6PGP7
NWLEKQQGNQERHLR	ZNF286B	161	P0CG31
RRQLLEEFEWLQQHT	XPNPEP2	631	O43895
DAHVREKLIWLRQQQ	TRIM23	311	P36406
LQWQEEERAHRQQQE	TCHH	746	Q07283
QEVAQEAWQNHKRRN	USP11	436	P51784
EAWQNHKRRNDSVIV	USP11	441	P51784
AERQDNKENWLHSQQ	SMTN	56	P53814
NKENWLHSQQREAEQ	SMTN	61	P53814
WEQQRHQLERRKEEL	TTLL7	416	Q6ZT98
TWIHEINQILENQRN	TRIO	2261	O75962
QLDRQQENWKRHLGS	ZFP90	126	Q8TF47
VHDRLLNVWQVRSEN	WDR43	241	Q15061
QTWKHQLEEELRQQK	TPX2	606	Q9ULW0