Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNHD1 PAFAH1B1 DNAH9 HTT

9.91e-0637734GO:0045505
GeneOntologyMolecularFunctionpeptide lactyltransferase (CoA-dependent) activity

CREBBP EP300

1.32e-052732GO:0120300
GeneOntologyMolecularFunctionhistone H3K27 acetyltransferase activity

CREBBP EP300

1.32e-052732GO:0044017
GeneOntologyMolecularFunctionhistone H3K18 acetyltransferase activity

CREBBP EP300

3.95e-053732GO:0043993
GeneOntologyMolecularFunctioncytoskeleton-nuclear membrane anchor activity

SYNE1 SYNE2

1.31e-045732GO:0140444
GeneOntologyMolecularFunctionhistone modifying activity

TTLL12 JARID2 DOT1L KDM4E CREBBP EP300

1.91e-04229736GO:0140993
GeneOntologyMolecularFunctionNAD+ nucleosidase activity

SARM1 IL1RL2

8.50e-0412732GO:0003953
GeneOntologyMolecularFunctiondynactin binding

PAFAH1B1 HTT

8.50e-0412732GO:0034452
GeneOntologyMolecularFunctionhistone H3 acetyltransferase activity

CREBBP EP300

1.34e-0315732GO:0010484
GeneOntologyMolecularFunctionNAD+ nucleotidase, cyclic ADP-ribose generating

SARM1 IL1RL2

1.53e-0316732GO:0061809
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNHD1 DNAH9

1.94e-0318732GO:0008569
GeneOntologyMolecularFunctionprotein-lysine N-methyltransferase activity

TTLL12 JARID2 DOT1L

1.98e-0368733GO:0016279
GeneOntologyMolecularFunctionlysine N-methyltransferase activity

TTLL12 JARID2 DOT1L

2.07e-0369733GO:0016278
GeneOntologyMolecularFunctionhistone methyltransferase activity

TTLL12 JARID2 DOT1L

2.24e-0371733GO:0042054
GeneOntologyMolecularFunctionperoxisome proliferator activated receptor binding

CREBBP EP300

2.65e-0321732GO:0042975
GeneOntologyMolecularFunctionp53 binding

CREBBP EP300 HTT

2.82e-0377733GO:0002039
GeneOntologyMolecularFunctionchromatin DNA binding

GLI2 KDM4E CREBBP EP300

3.28e-03167734GO:0031490
GeneOntologyMolecularFunctiondamaged DNA binding

KDM4E CREBBP EP300

3.61e-0384733GO:0003684
GeneOntologyBiologicalProcessneuron projection morphogenesis

CDKL5 GLI2 SYNE1 PPP1R9A PAFAH1B1 SARM1 ZSWIM6 PTEN ARHGEF25 EP300 PLXNA1 UNC13A NOTCH3 WDR47

4.95e-078027114GO:0048812
GeneOntologyBiologicalProcessplasma membrane bounded cell projection morphogenesis

CDKL5 GLI2 SYNE1 PPP1R9A PAFAH1B1 SARM1 ZSWIM6 PTEN ARHGEF25 EP300 PLXNA1 UNC13A NOTCH3 WDR47

6.36e-078197114GO:0120039
GeneOntologyBiologicalProcesscell projection morphogenesis

CDKL5 GLI2 SYNE1 PPP1R9A PAFAH1B1 SARM1 ZSWIM6 PTEN ARHGEF25 EP300 PLXNA1 UNC13A NOTCH3 WDR47

7.04e-078267114GO:0048858
GeneOntologyBiologicalProcesscell morphogenesis involved in neuron differentiation

CDKL5 GLI2 SYNE1 PPP1R9A PAFAH1B1 SARM1 PTEN ARHGEF25 EP300 PLXNA1 NOTCH3 WDR47

8.51e-067487112GO:0048667
GeneOntologyBiologicalProcessmotile cilium assembly

CFAP47 DNHD1 DZIP1 HTT ZMYND12

1.31e-0588715GO:0044458
GeneOntologyBiologicalProcesscentral nervous system neuron axonogenesis

GLI2 PAFAH1B1 PTEN WDR47

1.44e-0543714GO:0021955
GeneOntologyBiologicalProcessregulation of dendritic spine development

CDKL5 PPP1R9A PAFAH1B1 PTEN CREBBP

1.55e-0591715GO:0060998
GeneOntologyBiologicalProcessregulation of plasma membrane bounded cell projection assembly

CDKL5 SYNE1 PPP1R9A SYNE2 DZIP1 PLD1 HTT

2.31e-05248717GO:0120032
GeneOntologyBiologicalProcesscentral nervous system neuron development

GLI2 PAFAH1B1 PTEN PLXNA1 WDR47

2.33e-0599715GO:0021954
GeneOntologyBiologicalProcessregulation of cell projection assembly

CDKL5 SYNE1 PPP1R9A SYNE2 DZIP1 PLD1 HTT

2.49e-05251717GO:0060491
GeneOntologyBiologicalProcessneuron projection development

CDKL5 GLI2 SYNE1 PPP1R9A PAFAH1B1 SARM1 ZSWIM6 PTEN ARHGEF25 CREBBP EP300 PLXNA1 UNC13A NOTCH3 WDR47

2.55e-0512857115GO:0031175
GeneOntologyBiologicalProcessregulation of plasma membrane bounded cell projection organization

CDKL5 SYNE1 PPP1R9A PAFAH1B1 SYNE2 SARM1 DZIP1 PLD1 PTEN EP300 PLXNA1 HTT

2.89e-058467112GO:0120035
GeneOntologyBiologicalProcessneuron development

CDKL5 GLI2 SYNE1 PPP1R9A PAFAH1B1 SARM1 ZSWIM6 PTEN ARHGEF25 CREBBP EP300 PLXNA1 UNC13A NOTCH3 HTT WDR47

2.91e-0514637116GO:0048666
GeneOntologyBiologicalProcessregulation of cell projection organization

CDKL5 SYNE1 PPP1R9A PAFAH1B1 SYNE2 SARM1 DZIP1 PLD1 PTEN EP300 PLXNA1 HTT

3.51e-058637112GO:0031344
GeneOntologyBiologicalProcessregulation of cilium assembly

CDKL5 SYNE1 SYNE2 DZIP1 HTT

3.55e-05108715GO:1902017
GeneOntologyBiologicalProcesssperm flagellum assembly

CFAP47 DNHD1 DZIP1 ZMYND12

4.14e-0556714GO:0120316
GeneOntologyBiologicalProcessforebrain development

GLI2 PAFAH1B1 SYNE2 ZSWIM6 PTEN PLXNA1 NOTCH3 HTT WDR47

4.44e-05489719GO:0030900
GeneOntologyBiologicalProcesscell morphogenesis

CDKL5 GLI2 SYNE1 PPP1R9A PAFAH1B1 SARM1 ZSWIM6 PTEN ARHGEF25 EP300 PLXNA1 UNC13A NOTCH3 WDR47

4.75e-0511947114GO:0000902
GeneOntologyBiologicalProcessdendrite morphogenesis

CDKL5 SYNE1 PPP1R9A PAFAH1B1 SARM1 PTEN

6.19e-05198716GO:0048813
GeneOntologyBiologicalProcessN-terminal peptidyl-lysine acetylation

CREBBP EP300

6.98e-054712GO:0018076
GeneOntologyBiologicalProcessneuron projection extension

CDKL5 PAFAH1B1 PTEN EP300 PLXNA1 UNC13A

7.91e-05207716GO:1990138
GeneOntologyBiologicalProcessplasma membrane bounded cell projection assembly

CFAP47 DNHD1 CDKL5 SYNE1 PPP1R9A SYNE2 DZIP1 PLD1 HTT ZMYND12

9.45e-056707110GO:0120031
GeneOntologyBiologicalProcesspositive regulation of dendritic spine development

CDKL5 PPP1R9A PAFAH1B1 CREBBP

9.96e-0570714GO:0060999
GeneOntologyBiologicalProcesscentral nervous system neuron differentiation

GLI2 PAFAH1B1 ZSWIM6 PTEN PLXNA1 WDR47

1.03e-04217716GO:0021953
GeneOntologyBiologicalProcesscell projection assembly

CFAP47 DNHD1 CDKL5 SYNE1 PPP1R9A SYNE2 DZIP1 PLD1 HTT ZMYND12

1.13e-046857110GO:0030031
GeneOntologyBiologicalProcessdendritic spine development

CDKL5 PPP1R9A PAFAH1B1 PTEN CREBBP

1.26e-04141715GO:0060996
GeneOntologyBiologicalProcessaxonogenesis

CDKL5 GLI2 PAFAH1B1 PTEN ARHGEF25 EP300 PLXNA1 NOTCH3 WDR47

1.36e-04566719GO:0007409
GeneOntologyBiologicalProcesscilium assembly

CFAP47 DNHD1 CDKL5 SYNE1 SYNE2 DZIP1 HTT ZMYND12

1.41e-04444718GO:0060271
GeneOntologyBiologicalProcesscerebral cortex radial glia-guided migration

PAFAH1B1 SYNE2 WDR47

1.48e-0430713GO:0021801
GeneOntologyBiologicalProcesstelencephalon glial cell migration

PAFAH1B1 SYNE2 WDR47

1.48e-0430713GO:0022030
GeneOntologyBiologicalProcessdendrite development

CDKL5 SYNE1 PPP1R9A PAFAH1B1 SARM1 PTEN CREBBP

1.53e-04335717GO:0016358
GeneOntologyBiologicalProcesscentral nervous system projection neuron axonogenesis

GLI2 PAFAH1B1 WDR47

1.80e-0432713GO:0021952
GeneOntologyBiologicalProcessnuclear migration

SYNE1 PAFAH1B1 SYNE2

2.17e-0434713GO:0007097
GeneOntologyBiologicalProcesscilium organization

CFAP47 DNHD1 CDKL5 SYNE1 SYNE2 DZIP1 HTT ZMYND12

2.26e-04476718GO:0044782
GeneOntologyBiologicalProcesscentrosome localization

SYNE1 PAFAH1B1 SYNE2

2.36e-0435713GO:0051642
GeneOntologyBiologicalProcessmicrotubule organizing center localization

SYNE1 PAFAH1B1 SYNE2

2.57e-0436713GO:0061842
GeneOntologyBiologicalProcessmicrotubule-based movement

CFAP47 DNHD1 PAFAH1B1 SYNE2 DZIP1 DNAH9 HTT ZMYND12

2.86e-04493718GO:0007018
GeneOntologyBiologicalProcesshead development

GLI2 PAFAH1B1 SYNE2 ZSWIM6 PTEN CREBBP EP300 PLXNA1 NOTCH3 HTT WDR47

2.86e-049197111GO:0060322
GeneOntologyBiologicalProcesslearning or memory

RAPGEF3 PAFAH1B1 NTS PTEN CREBBP EP300 HTT

2.94e-04373717GO:0007611
GeneOntologyBiologicalProcessaxon development

CDKL5 GLI2 PAFAH1B1 PTEN ARHGEF25 EP300 PLXNA1 NOTCH3 WDR47

3.45e-04642719GO:0061564
GeneOntologyBiologicalProcesscerebral cortex radially oriented cell migration

PAFAH1B1 SYNE2 WDR47

4.08e-0442713GO:0021799
GeneOntologyBiologicalProcessregulation of dendrite morphogenesis

CDKL5 SYNE1 PAFAH1B1 SARM1

4.41e-04103714GO:0048814
GeneOntologyBiologicalProcessnucleus localization

SYNE1 PAFAH1B1 SYNE2

4.68e-0444713GO:0051647
GeneOntologyBiologicalProcessregulation of axonogenesis

CDKL5 PAFAH1B1 PTEN EP300 PLXNA1

5.25e-04192715GO:0050770
GeneOntologyBiologicalProcessdevelopmental growth involved in morphogenesis

CDKL5 PAFAH1B1 PTEN EP300 PLXNA1 UNC13A

5.74e-04299716GO:0060560
GeneOntologyBiologicalProcessdevelopmental cell growth

CDKL5 PAFAH1B1 PTEN EP300 PLXNA1 UNC13A

5.94e-04301716GO:0048588
GeneOntologyBiologicalProcessregulation of developmental growth

CDKL5 JARID2 TLL2 PAFAH1B1 PTEN EP300 UNC13A

6.07e-04421717GO:0048638
GeneOntologyBiologicalProcesscognition

RAPGEF3 PAFAH1B1 NTS PTEN CREBBP EP300 HTT

6.24e-04423717GO:0050890
GeneOntologyBiologicalProcessnegative regulation of transcription by RNA polymerase I

DDX21 CREBBP

6.30e-0411712GO:0016479
GeneOntologyBiologicalProcesspositive regulation of axonogenesis

CDKL5 PAFAH1B1 EP300 PLXNA1

6.47e-04114714GO:0050772
GeneOntologyBiologicalProcesscilium movement involved in cell motility

CFAP47 DNHD1 DZIP1 DNAH9 ZMYND12

7.87e-04210715GO:0060294
GeneOntologyBiologicalProcessmicrotubule cytoskeleton organization

CFAP47 PAFAH1B1 SYNE2 CHD3 DZIP1 PTEN HTT ZMYND12 WDR47

7.88e-04720719GO:0000226
GeneOntologyBiologicalProcesscilium-dependent cell motility

CFAP47 DNHD1 DZIP1 DNAH9 ZMYND12

8.75e-04215715GO:0060285
GeneOntologyBiologicalProcesscilium or flagellum-dependent cell motility

CFAP47 DNHD1 DZIP1 DNAH9 ZMYND12

8.75e-04215715GO:0001539
GeneOntologyBiologicalProcesspositive regulation of axon extension

CDKL5 PAFAH1B1 EP300

9.02e-0455713GO:0045773
GeneOntologyBiologicalProcessbehavior

RAPGEF3 PAFAH1B1 NTS PTEN CREBBP EP300 MCOLN3 CRHR2 HTT WDR47

9.10e-048917110GO:0007610
GeneOntologyBiologicalProcessdefense response to other organism

TTLL12 ACOD1 NTS SARM1 PLD1 PTEN DDX21 TTC4 USP27X IL1RL2 TF CREBBP EP300

9.24e-0414077113GO:0098542
GeneOntologyBiologicalProcessmicrotubule-based process

CFAP47 DNHD1 PAFAH1B1 SYNE2 CHD3 DZIP1 PTEN DNAH9 HTT ZMYND12 WDR47

9.30e-0410587111GO:0007017
GeneOntologyBiologicalProcessprotein destabilization

CREBBP EP300 HTT

9.51e-0456713GO:0031648
GeneOntologyBiologicalProcesscerebral cortex cell migration

PAFAH1B1 SYNE2 WDR47

9.51e-0456713GO:0021795
GeneOntologyBiologicalProcesstelencephalon development

PAFAH1B1 SYNE2 ZSWIM6 PTEN HTT WDR47

9.89e-04332716GO:0021537
GeneOntologyBiologicalProcessskeletal muscle tissue growth

TLL2 CRHR2

1.04e-0314712GO:0048630
GeneOntologyBiologicalProcessregulation of cell size

CDKL5 RAPGEF3 PAFAH1B1 PTEN EP300

1.07e-03225715GO:0008361
GeneOntologyBiologicalProcessdevelopmental growth

CDKL5 JARID2 GLI2 TLL2 PAFAH1B1 PTEN EP300 PLXNA1 UNC13A CRHR2

1.08e-039117110GO:0048589
GeneOntologyBiologicalProcessregulation of neuron projection development

CDKL5 SYNE1 PPP1R9A PAFAH1B1 SARM1 PTEN EP300 PLXNA1

1.18e-03612718GO:0010975
GeneOntologyBiologicalProcessregulation of anatomical structure morphogenesis

CDKL5 RAPGEF3 SYNE1 PPP1R9A PAFAH1B1 SARM1 PTEN EP300 PLXNA1 UNC13A CRHR2

1.18e-0310907111GO:0022603
GeneOntologyBiologicalProcessnegative regulation of excitatory postsynaptic potential

SYNE1 PTEN

1.19e-0315712GO:0090394
GeneOntologyBiologicalProcessN-terminal protein amino acid acetylation

CREBBP EP300

1.36e-0316712GO:0006474
GeneOntologyBiologicalProcessregulation of cellular response to heat

CREBBP EP300

1.36e-0316712GO:1900034
GeneOntologyBiologicalProcessregulation of dendritic spine morphogenesis

PPP1R9A PAFAH1B1 PTEN

1.40e-0364713GO:0061001
GeneOntologyBiologicalProcessregulation of collagen biosynthetic process

RAPGEF3 GLI2 EP300

1.47e-0365713GO:0032965
GeneOntologyBiologicalProcesspositive regulation of cell projection organization

CDKL5 PPP1R9A PAFAH1B1 DZIP1 EP300 PLXNA1 HTT

1.54e-03494717GO:0031346
GeneOntologyBiologicalProcesslong-term synaptic potentiation

PPP1R9A PTEN UNC13A CRHR2

1.54e-03144714GO:0060291
GeneOntologyCellularComponentsomatodendritic compartment

CDKL5 DRP2 RAPGEF3 SYNE1 PPP1R9A PAFAH1B1 NTS SARM1 PTEN TF DDC CRHR2 HTT WDR47

1.21e-0412287614GO:0036477
GeneOntologyCellularComponentdistal axon

CDKL5 RAPGEF3 PPP1R9A PAFAH1B1 NTS UNC13A CRHR2 WDR47

1.80e-04435768GO:0150034
GeneOntologyCellularComponentmotile cilium

CFAP47 DNHD1 GLI2 PAFAH1B1 DNAH9 MORN5 ZMYND12

3.07e-04355767GO:0031514
GeneOntologyCellularComponentcytoplasmic region

DNHD1 CDKL5 GLI2 PAFAH1B1 DNAH9 UNC13A HTT

3.34e-04360767GO:0099568
GeneOntologyCellularComponentaxon

CDKL5 RAPGEF3 PPP1R9A PAFAH1B1 NTS SARM1 DDC UNC13A CRHR2 HTT WDR47

3.60e-048917611GO:0030424
GeneOntologyCellularComponentactin-based cell projection

RAPGEF3 PPP1R9A PAFAH1B1 SYNE2 ZSWIM6 UTRN

5.26e-04278766GO:0098858
GeneOntologyCellularComponentmicrotubule organizing center attachment site

SYNE1 SYNE2

7.02e-0411762GO:0034992
GeneOntologyCellularComponentmeiotic nuclear membrane microtubule tethering complex

SYNE1 SYNE2

7.02e-0411762GO:0034993
GeneOntologyCellularComponentnuclear membrane protein complex

SYNE1 SYNE2

7.02e-0411762GO:0106083
GeneOntologyCellularComponentnuclear membrane microtubule tethering complex

SYNE1 SYNE2

7.02e-0411762GO:0106094
GeneOntologyCellularComponentneuromuscular junction

PPP1R9A SARM1 UTRN UNC13A

7.45e-04112764GO:0031594
GeneOntologyCellularComponentplasma membrane bounded cell projection cytoplasm

DNHD1 CDKL5 GLI2 PAFAH1B1 DNAH9 HTT

1.04e-03317766GO:0032838
GeneOntologyCellularComponentfilopodium

RAPGEF3 PPP1R9A SYNE2 UTRN

1.06e-03123764GO:0030175
GeneOntologyCellularComponentdendrite

CDKL5 DRP2 SYNE1 PPP1R9A SARM1 PTEN TF CRHR2 HTT WDR47

1.06e-038587610GO:0030425
GeneOntologyCellularComponentdendritic tree

CDKL5 DRP2 SYNE1 PPP1R9A SARM1 PTEN TF CRHR2 HTT WDR47

1.08e-038607610GO:0097447
GeneOntologyCellularComponentPML body

TOPBP1 CHD3 PTEN CREBBP

1.12e-03125764GO:0016605
GeneOntologyCellularComponentlate endosome

PLD1 MON1A RUFY1 TF MCOLN3 HTT

1.67e-03348766GO:0005770
GeneOntologyCellularComponentgrowth cone

CDKL5 RAPGEF3 PPP1R9A PAFAH1B1 WDR47

1.99e-03245765GO:0030426
GeneOntologyCellularComponentsite of polarized growth

CDKL5 RAPGEF3 PPP1R9A PAFAH1B1 WDR47

2.29e-03253765GO:0030427
GeneOntologyCellularComponentfilopodium membrane

SYNE2 UTRN

2.62e-0321762GO:0031527
GeneOntologyCellularComponentneuronal cell body

DRP2 RAPGEF3 PPP1R9A PAFAH1B1 NTS DDC CRHR2 HTT WDR47

3.22e-03835769GO:0043025
GeneOntologyCellularComponentaxonemal dynein complex

DNHD1 DNAH9

3.71e-0325762GO:0005858
HumanPhenoDilation of Virchow-Robin spaces

PAFAH1B1 ZSWIM6 PTEN PLXNA1

1.56e-0618264HP:0012520
HumanPhenoAbnormal subclavian artery morphology

PLD1 CREBBP EP300

1.90e-0511263HP:0031251
HumanPhenoAbnormal branching pattern of the aortic arch

PLD1 DNAH9 CREBBP EP300

1.97e-0533264HP:0011587
HumanPhenoPlantar crease between first and second toes

CREBBP EP300

2.51e-052262HP:0008107
HumanPhenoAortic isthmus hypoplasia

CREBBP EP300

2.51e-052262HP:0034227
HumanPhenoHigh axial triradius

CREBBP EP300

2.51e-052262HP:0001042
HumanPhenoProminent forehead

CDKL5 JARID2 GLI2 CHD3 ZSWIM6 PTEN CREBBP EP300

2.98e-05261268HP:0011220
HumanPhenoKeloids

CREBBP EP300 NOTCH3

3.26e-0513263HP:0010562
HumanPhenoParietal foramina

ZSWIM6 CREBBP EP300

4.14e-0514263HP:0002697
HumanPhenoPerseverative thought

CDKL5 JARID2 CHD3 ZSWIM6 CREBBP DDC EP300 NOTCH3 HTT

6.09e-05377269HP:0030223
HumanPhenoDisordered formal thought process

CDKL5 JARID2 CHD3 ZSWIM6 CREBBP DDC EP300 NOTCH3 HTT

7.34e-05386269HP:0025769
HumanPhenoLaryngeal cartilage malformation

CREBBP EP300

7.49e-053262HP:0008752
HumanPhenoPhobia

CREBBP EP300

7.49e-053262HP:5200232
HumanPhenoAgoraphobia

CREBBP EP300

7.49e-053262HP:0000756
HumanPhenoHumoral immunodeficiency

CREBBP EP300

7.49e-053262HP:0005363
HumanPhenoProminent nasal septum

CREBBP EP300

7.49e-053262HP:0005322
HumanPhenoRadial deviation of thumb terminal phalanx

CREBBP EP300

7.49e-053262HP:0005895
HumanPhenoAdvanced eruption of teeth

CHD6 ZSWIM6 CREBBP EP300

7.53e-0546264HP:0006288
HumanPhenoTongue thrusting

CDKL5 ZSWIM6 DDC

7.66e-0517263HP:0100703
HumanPhenoBroad phalanx of the toes

CDKL5 PTEN CREBBP EP300

8.20e-0547264HP:0010174
HumanPhenoSkin appendage neoplasm

PTEN CREBBP EP300

9.16e-0518263HP:0012842
HumanPhenoAbnormal thought pattern

CDKL5 JARID2 CHD3 ZSWIM6 CREBBP DDC EP300 NOTCH3 HTT

1.05e-04404269HP:5200269
HumanPhenoPtosis

JARID2 GLI2 SYNE1 SYNE2 ZSWIM6 PTEN CREBBP DDC EP300 PLXNA1 NOTCH3 CAPN15

1.32e-047542612HP:0000508
HumanPhenoTrichiasis

CREBBP EP300

1.49e-044262HP:0001128
HumanPhenoVisceral hemangioma

CREBBP EP300

1.49e-044262HP:0410266
HumanPhenoTalon cusp

CREBBP EP300

1.49e-044262HP:0011087
HumanPhenoWidened distal phalanges

CREBBP EP300

1.49e-044262HP:0006200
HumanPhenoVascular ring

CREBBP EP300

1.49e-044262HP:0010775
HumanPhenoHepatic hemangioma

CREBBP EP300

1.49e-044262HP:0031207
HumanPhenoBenign neoplasm of the central nervous system

ZSWIM6 PTEN CREBBP EP300 NOTCH3

1.58e-04105265HP:0100835
HumanPhenoAbnormal spermatogenesis

CFAP47 DNHD1 GLI2 SYNE1 PAFAH1B1 CHD3 CHD6 ZSWIM6 DZIP1 PLD1 PTEN DNAH9 CREBBP EP300 NOTCH3

1.68e-0411902615HP:0008669
HumanPhenoSimple ear

CREBBP EP300 CAPN15

2.23e-0424263HP:0020206
HumanPhenoPapillary cystadenoma of the epididymis

CREBBP EP300

2.48e-045262HP:0009715
HumanPhenoRib exostoses

CHD6 PTEN

2.48e-045262HP:0000896
HumanPhenoSupernumerary cusp

CREBBP EP300

2.48e-045262HP:0033777
HumanPhenoEpididymal neoplasm

CREBBP EP300

2.48e-045262HP:0030421
HumanPhenoSteroetypic movements of face and head

CDKL5 ZSWIM6 DDC HTT

2.59e-0463264HP:5200017
HumanPhenoAbnormal male internal genitalia morphology

CFAP47 DNHD1 GLI2 SYNE1 PAFAH1B1 CHD3 CHD6 ZSWIM6 DZIP1 PLD1 PTEN DNAH9 CREBBP EP300 NOTCH3

2.82e-0412432615HP:0000022
HumanPhenoPerimembranous ventricular septal defect

CHD3 CREBBP EP300

2.84e-0426263HP:0011682
HumanPhenoRestricted or repetitive behaviors or interests

CDKL5 JARID2 CHD3 ZSWIM6 CREBBP DDC EP300 HTT

3.38e-04368268HP:0031432
HumanPhenoAbsent sperm flagella

CFAP47 DNHD1 DZIP1

3.55e-0428263HP:0032558
HumanPhenoFunctional abnormality of male internal genitalia

CFAP47 DNHD1 GLI2 SYNE1 PAFAH1B1 CHD3 CHD6 ZSWIM6 DZIP1 PLD1 PTEN DNAH9 CREBBP EP300 NOTCH3

3.61e-0412692615HP:0000025
HumanPhenoAbnormally slow thought process

NOTCH3 HTT

3.71e-046262HP:0031843
HumanPhenoAbnormal muscle fiber emerin

SYNE1 SYNE2

3.71e-046262HP:0030116
HumanPhenoAbsent muscle fiber emerin

SYNE1 SYNE2

3.71e-046262HP:0030117
HumanPhenoLarge foramen magnum

CREBBP EP300

3.71e-046262HP:0002700
HumanPhenoMotor stereotypy

CDKL5 CHD3 ZSWIM6 CREBBP DDC EP300 HTT

3.74e-04280267HP:0000733
HumanPhenoAbnormality of the male genitalia

CFAP47 DNHD1 CDKL5 GLI2 SYNE1 PAFAH1B1 CHD3 CHD6 ZSWIM6 DZIP1 PLD1 PTEN DNAH9 CREBBP EP300 NOTCH3

3.86e-0414372616HP:0010461
HumanPhenoAbnormal parietal bone morphology

ZSWIM6 CREBBP EP300

3.95e-0429263HP:0002696
HumanPhenoPreaxial foot polydactyly

ZSWIM6 CREBBP EP300

4.37e-0430263HP:0001841
HumanPhenoDeep philtrum

CDKL5 JARID2 CREBBP EP300

5.07e-0475264HP:0002002
HumanPhenoDecreased cervical spine flexion due to contractures of posterior cervical muscles

SYNE1 SYNE2

5.18e-047262HP:0004631
HumanPhenoDeviated nasal septum

CREBBP EP300

5.18e-047262HP:0004411
HumanPhenoAbnormal male reproductive system physiology

CFAP47 DNHD1 GLI2 SYNE1 PAFAH1B1 CHD3 CHD6 ZSWIM6 DZIP1 PLD1 PTEN DNAH9 CREBBP EP300 NOTCH3

5.43e-0413142615HP:0012874
HumanPhenoSyringomyelia

CREBBP EP300 NOTCH3

5.82e-0433263HP:0003396
HumanPhenoMovement abnormality of the tongue

CDKL5 ZSWIM6 DDC

5.82e-0433263HP:0000182
HumanPhenoShort sperm flagella

CFAP47 DNHD1 DZIP1

5.82e-0433263HP:0032559
HumanPhenoAbnormal internal genitalia

CFAP47 DNHD1 GLI2 SYNE1 PAFAH1B1 CHD3 CHD6 ZSWIM6 DZIP1 PLD1 PTEN DNAH9 CREBBP EP300 NOTCH3 CAPN15

6.46e-0414982616HP:0000812
HumanPhenoHydrocele testis

PTEN CREBBP EP300

7.54e-0436263HP:0000034
HumanPhenoPilomatrixoma

CREBBP EP300

8.82e-049262HP:0030434
HumanPhenoCervical cord compression

CREBBP EP300

8.82e-049262HP:0002341
HumanPhenoNatal tooth

CHD6 CREBBP EP300

8.85e-0438263HP:0000695
HumanPhenoAbnormal nasolacrimal system morphology

GLI2 IL2RB CREBBP EP300

8.91e-0487264HP:0000614
HumanPhenoDeviation of the hallux

CDKL5 PTEN CREBBP EP300

9.30e-0488264HP:0010051
HumanPhenoCapillary hemangioma

PTEN CREBBP EP300

9.55e-0439263HP:0005306
HumanPhenoCellular immunodeficiency

PTEN CREBBP EP300

9.55e-0439263HP:0005374
HumanPhenoHigh, narrow palate

CHD6 PTEN CREBBP EP300 NOTCH3

9.87e-04156265HP:0002705
HumanPhenoCompulsive behaviors

JARID2 ZSWIM6 CREBBP EP300 HTT

1.05e-03158265HP:0000722
HumanPhenoFrontal hirsutism

CREBBP EP300

1.10e-0310262HP:0011335
HumanPhenoAutistic behavior

CDKL5 JARID2 CHD3 ZSWIM6 PTEN CREBBP DDC EP300 PLXNA1 CAPN15

1.16e-036782610HP:0000729
HumanPhenoHyperactivity

CDKL5 JARID2 GLI2 CHD3 ZSWIM6 PTEN CREBBP EP300 HTT

1.20e-03558269HP:0000752
HumanPhenoMood alterations

CREBBP DDC EP300 UNC13A NOTCH3

1.24e-03164265HP:0001296
HumanPhenoEmotional lability

CREBBP DDC EP300 UNC13A NOTCH3

1.24e-03164265HP:0000712
HumanPhenoAbnormal sperm tail morphology

CFAP47 DNHD1 DZIP1

1.27e-0343263HP:0012868
HumanPhenoAbnormal columella morphology

ZSWIM6 CREBBP EP300 CAPN15

1.34e-0397264HP:0009929
HumanPhenoVentricular escape rhythm

SYNE1 SYNE2

1.34e-0311262HP:0005155
HumanPhenoMeningioma

PTEN CREBBP EP300

1.36e-0344263HP:0002858
HumanPhenoSpina bifida

GLI2 ZSWIM6 CREBBP EP300 NOTCH3

1.49e-03171265HP:0002414
HumanPhenoSpinal cord lesion

CREBBP EP300 NOTCH3

1.55e-0346263HP:0100561
HumanPhenoProminent fingertip pads

JARID2 CREBBP EP300

1.55e-0346263HP:0001212
HumanPhenoSevere cytomegalovirus infection

PTEN IL2RB

1.60e-0312262HP:0031692
HumanPhenoSporadic

GLI2 PAFAH1B1 CREBBP EP300

1.67e-03103264HP:0003745
HumanPhenoChiari type I malformation

CREBBP EP300 NOTCH3

1.75e-0348263HP:0007099
HumanPhenoProminent digit pad

JARID2 CREBBP EP300

1.75e-0348263HP:0011298
HumanPhenoAbnormal aortic morphology

GLI2 PLD1 PTEN DNAH9 CREBBP EP300 NOTCH3

1.77e-03363267HP:0030963
HumanPhenoNeoplasm of the central nervous system

ZSWIM6 PTEN CREBBP EP300 NOTCH3

1.78e-03178265HP:0100006
MousePhenoimpaired coordination

CDKL5 GLI2 SYNE1 PAFAH1B1 CHD6 ZSWIM6 CREBBP DDC MCOLN3 HTT

2.77e-054785910MP:0001405
MousePhenoabnormal motor coordination/balance

CDKL5 GLI2 SYNE1 PAFAH1B1 CHD6 ZSWIM6 PTEN TF CREBBP DDC MCOLN3 NOTCH3 HTT

5.55e-058735913MP:0001516
DomainZZ

DRP2 UTRN CREBBP EP300

6.66e-0718744PF00569
DomainZF_ZZ_2

DRP2 UTRN CREBBP EP300

6.66e-0718744PS50135
DomainZF_ZZ_1

DRP2 UTRN CREBBP EP300

6.66e-0718744PS01357
DomainZnf_ZZ

DRP2 UTRN CREBBP EP300

8.41e-0719744IPR000433
DomainZnF_ZZ

DRP2 UTRN CREBBP EP300

8.41e-0719744SM00291
DomainSpectrin

DRP2 SYNE1 SYNE2 UTRN

1.90e-0623744PF00435
DomainSpectrin_repeat

DRP2 SYNE1 SYNE2 UTRN

5.00e-0629744IPR002017
DomainSpectrin/alpha-actinin

DRP2 SYNE1 SYNE2 UTRN

7.51e-0632744IPR018159
DomainSPEC

DRP2 SYNE1 SYNE2 UTRN

7.51e-0632744SM00150
DomainNuc_rcpt_coact_CREBbp

CREBBP EP300

1.55e-052742IPR014744
DomainHAT_KAT11

CREBBP EP300

1.55e-052742PF08214
DomainKIX

CREBBP EP300

1.55e-052742PS50952
DomainZnF_TAZ

CREBBP EP300

1.55e-052742SM00551
DomainCBP_P300_HAT

CREBBP EP300

1.55e-052742IPR031162
DomainDUF902

CREBBP EP300

1.55e-052742PF06001
Domain-

CREBBP EP300

1.55e-0527421.20.1020.10
DomainRING_CBP-p300

CREBBP EP300

1.55e-052742IPR010303
Domain-

CREBBP EP300

1.55e-0527421.10.1630.10
DomainCreb_binding

CREBBP EP300

1.55e-052742PF09030
Domain-

CREBBP EP300

1.55e-0527421.10.246.20
Domainzf-TAZ

CREBBP EP300

1.55e-052742PF02135
DomainZF_TAZ

CREBBP EP300

1.55e-052742PS50134
DomainHistone_AcTrfase_Rtt109/CBP

CREBBP EP300

1.55e-052742IPR013178
DomainKAT11

CREBBP EP300

1.55e-052742SM01250
DomainZnf_TAZ

CREBBP EP300

1.55e-052742IPR000197
DomainKIX_dom

CREBBP EP300

1.55e-052742IPR003101
DomainKIX

CREBBP EP300

1.55e-052742PF02172
DomainCBP_P300_HAT

CREBBP EP300

1.55e-052742PS51727
DomainKASH

SYNE1 SYNE2

9.24e-054742PF10541
DomainKASH

SYNE1 SYNE2

9.24e-054742IPR012315
DomainKASH

SYNE1 SYNE2

9.24e-054742PS51049
DomainKASH

SYNE1 SYNE2

9.24e-054742SM01249
DomainActinin_actin-bd_CS

SYNE1 SYNE2 UTRN

9.99e-0523743IPR001589
DomainACTININ_2

SYNE1 SYNE2 UTRN

9.99e-0523743PS00020
DomainACTININ_1

SYNE1 SYNE2 UTRN

9.99e-0523743PS00019
DomainCH

CFAP47 SYNE1 SYNE2 UTRN

1.71e-0470744PF00307
Domain-

CFAP47 SYNE1 SYNE2 UTRN

1.80e-04717441.10.418.10
DomainCH

CFAP47 SYNE1 SYNE2 UTRN

2.01e-0473744PS50021
DomainCH-domain

CFAP47 SYNE1 SYNE2 UTRN

2.23e-0475744IPR001715
DomainNuc_rcpt_coact

CREBBP EP300

2.30e-046742IPR009110
DomainEF-hand_dom_typ1

DRP2 UTRN

2.30e-046742IPR015153
DomainEF-hand_dom_typ2

DRP2 UTRN

2.30e-046742IPR015154
DomainEF-hand_2

DRP2 UTRN

2.30e-046742PF09068
DomainEF-hand_3

DRP2 UTRN

2.30e-046742PF09069
DomainJmjN

JARID2 KDM4E

6.83e-0410742SM00545
DomainJMJN

JARID2 KDM4E

6.83e-0410742PS51183
DomainJmjN

JARID2 KDM4E

6.83e-0410742PF02375
DomainJmjN

JARID2 KDM4E

6.83e-0410742IPR003349
DomainDynein_HC_stalk

DNHD1 DNAH9

1.37e-0314742IPR024743
DomainDynein_heavy_dom-2

DNHD1 DNAH9

1.37e-0314742IPR013602
DomainDHC_N2

DNHD1 DNAH9

1.37e-0314742PF08393
DomainMT

DNHD1 DNAH9

1.37e-0314742PF12777
DomainDHC_fam

DNHD1 DNAH9

1.57e-0315742IPR026983
DomainDynein_heavy_dom

DNHD1 DNAH9

1.57e-0315742IPR004273
DomainDynein_heavy

DNHD1 DNAH9

1.57e-0315742PF03028
DomainAT_hook

CCDC71 DOT1L

1.79e-0316742PF02178
DomainCH

SYNE1 SYNE2 UTRN

2.19e-0365743SM00033
DomainTIR

SARM1 IL1RL2

3.10e-0321742SM00255
Domain-

SARM1 IL1RL2

3.71e-03237423.40.50.10140
DomainChromo_domain

CHD3 CHD6

4.04e-0324742IPR023780
DomainJmjC

JARID2 KDM4E

4.04e-0324742PF02373
DomainTIR

SARM1 IL1RL2

4.04e-0324742PS50104
DomainWD40_repeat_CS

FBXW9 PAFAH1B1 TBL3 WDR47

4.09e-03164744IPR019775
DomainTIR_dom

SARM1 IL1RL2

4.38e-0325742IPR000157
DomainG-protein_beta_WD-40_rep

FBXW9 PAFAH1B1 TBL3

4.67e-0385743IPR020472
DomainBromodomain_CS

CREBBP EP300

4.73e-0326742IPR018359
DomainChromo

CHD3 CHD6

4.73e-0326742PF00385
PathwayREACTOME_ZYGOTIC_GENOME_ACTIVATION_ZGA

KDM4E CREBBP EP300

3.29e-0517533M48025
PathwayWP_HEMATOPOIETIC_STEM_CELL_GENE_REGULATION_BY_GABP_ALPHABETA_COMPLEX

PTEN CREBBP EP300

6.36e-0521533M39593
PathwayREACTOME_NOTCH3_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

CREBBP EP300 NOTCH3

1.09e-0425533M27880
PathwayBIOCARTA_PELP1_PATHWAY

CREBBP EP300

1.38e-045532MM1575
PathwayREACTOME_NFE2L2_REGULATING_INFLAMMATION_ASSOCIATED_GENES

CREBBP EP300

1.38e-045532M48020
PathwayREACTOME_NFE2L2_REGULATING_ER_STRESS_ASSOCIATED_GENES

CREBBP EP300

1.38e-045532M48023
PathwayREACTOME_LRR_FLII_INTERACTING_PROTEIN_1_LRRFIP1_ACTIVATES_TYPE_I_IFN_PRODUCTION

CREBBP EP300

1.38e-045532M27228
PathwayBIOCARTA_PELP1_PATHWAY

CREBBP EP300

2.06e-046532M22062
PathwayBIOCARTA_PPARG_PATHWAY

CREBBP EP300

2.88e-047532MM1573
PathwayBIOCARTA_PPARG_PATHWAY

CREBBP EP300

3.83e-048532M22058
PathwayREACTOME_NFE2L2_REGULATING_MDR_ASSOCIATED_ENZYMES

CREBBP EP300

3.83e-048532M48022
PathwayREACTOME_REGULATION_OF_NFE2L2_GENE_EXPRESSION

CREBBP EP300

3.83e-048532M48024
PathwayREACTOME_NFE2L2_REGULATES_PENTOSE_PHOSPHATE_PATHWAY_GENES

CREBBP EP300

3.83e-048532M46443
PathwayKEGG_MEDICUS_REFERENCE_TLR3_IRF3_SIGNALING_PATHWAY

CREBBP EP300

4.91e-049532M47451
PathwayREACTOME_REGULATION_OF_FOXO_TRANSCRIPTIONAL_ACTIVITY_BY_ACETYLATION

CREBBP EP300

6.12e-0410532M27945
PathwayKEGG_NOTCH_SIGNALING_PATHWAY

CREBBP EP300 NOTCH3

7.24e-0447533M7946
PathwayBIOCARTA_CARM1_PATHWAY

CREBBP EP300

7.46e-0411532MM1521
PathwayREACTOME_NFE2L2_REGULATING_TUMORIGENIC_GENES

CREBBP EP300

7.46e-0411532M48021
PathwayREACTOME_REGULATION_OF_GENE_EXPRESSION_BY_HYPOXIA_INDUCIBLE_FACTOR

CREBBP EP300

7.46e-0411532M26924
PathwayWP_RETT_SYNDROME

CDKL5 SYNE2 HTT

7.70e-0448533M39759
PathwayREACTOME_SIGNALING_BY_NOTCH3

CREBBP EP300 NOTCH3

8.18e-0449533M618
PathwayBIOCARTA_CARM1_PATHWAY

CREBBP EP300

8.94e-0412532M7968
PathwayREACTOME_ACTIVATION_OF_THE_TFAP2_AP_2_FAMILY_OF_TRANSCRIPTION_FACTORS

CREBBP EP300

8.94e-0412532M27765
PathwayREACTOME_RUNX3_REGULATES_NOTCH_SIGNALING

CREBBP EP300

1.23e-0314532M27808
PathwayBIOCARTA_RELA_PATHWAY

CREBBP EP300

1.41e-0315532MM1339
PathwayBIOCARTA_RELA_PATHWAY

CREBBP EP300

1.41e-0315532M10183
PathwayBIOCARTA_PITX2_PATHWAY

CREBBP EP300

1.41e-0315532MM1439
PathwayWP_RUBINSTEINTAYBI_SYNDROME_1

DDX21 CREBBP

1.41e-0315532M48323
PathwayREACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY

CREBBP EP300

1.41e-0315532M953
PathwayREACTOME_REGULATION_OF_GENE_EXPRESSION_IN_LATE_STAGE_BRANCHING_MORPHOGENESIS_PANCREATIC_BUD_PRECURSOR_CELLS

CREBBP EP300

1.61e-0316532M27121
PathwayBIOCARTA_IL7_PATHWAY

CREBBP EP300

1.61e-0316532M1296
PathwayBIOCARTA_IL7_PATHWAY

CREBBP EP300

1.61e-0316532MM1420
PathwayBIOCARTA_PITX2_PATHWAY

CREBBP EP300

1.61e-0316532M8516
PathwayREACTOME_FOXO_MEDIATED_TRANSCRIPTION_OF_CELL_DEATH_GENES

CREBBP EP300

1.61e-0316532M27940
PathwayPID_P53_DOWNSTREAM_PATHWAY

PTEN CREBBP EP300 HTT

1.73e-03137534M145
PathwayBIOCARTA_TGFB_PATHWAY

CREBBP EP300

1.82e-0317532MM1509
PathwayWP_PATHWAYS_AFFECTED_IN_ADENOID_CYSTIC_CARCINOMA

PTEN CREBBP EP300

1.86e-0365533M39682
PathwayPID_HIF1_TFPATHWAY

TF CREBBP EP300

1.94e-0366533M255
PathwayPID_HDAC_CLASSI_PATHWAY

CHD3 CREBBP EP300

1.94e-0366533M101
PathwayREACTOME_RORA_ACTIVATES_GENE_EXPRESSION

CREBBP EP300

2.04e-0318532M26942
PathwayWP_UROTENSINIIMEDIATED_SIGNALING

PTEN CREBBP EP300

2.21e-0369533M48052
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_TP53

ELOA TOPBP1 CHD3 PTEN CREBBP EP300

2.22e-03360536M27267
PathwayBIOCARTA_TGFB_PATHWAY

CREBBP EP300

2.28e-0319532M18933
PathwayREACTOME_NFE2L2_REGULATING_ANTI_OXIDANT_DETOXIFICATION_ENZYMES

CREBBP EP300

2.28e-0319532M46442
PathwayKEGG_LONG_TERM_POTENTIATION

RAPGEF3 CREBBP EP300

2.30e-0370533M3115
PathwayPID_AP1_PATHWAY

NTS PTEN EP300

2.30e-0370533M167
Pubmed

STAG3, a novel gene encoding a protein involved in meiotic chromosome pairing and location of STAG3-related genes flanking the Williams-Beuren syndrome deletion.

STAG3L1 STAG3L2 STAG3L3

1.00e-07576310698974
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

TMEM144 LUC7L3 STAG3L1 GLI2 PPP1R9A CHD3 CHD6 ELK3 ZSWIM6 PTEN UTRN CREBBP EP300 NOTCH3 HTT

6.73e-071489761528611215
Pubmed

The centrosomal deubiquitylase USP21 regulates Gli1 transcriptional activity and stability.

GLI2 SYNE1 WDR47

1.63e-061176327621083
Pubmed

SUN1/2 and Syne/Nesprin-1/2 complexes connect centrosome to the nucleus during neurogenesis and neuronal migration in mice.

SYNE1 PAFAH1B1 SYNE2

3.59e-061476319874786
Pubmed

Loss of p300 accelerates MDS-associated leukemogenesis.

CREBBP EP300

4.71e-06276227881875
Pubmed

Molecular characterization of the histone acetyltransferase CREBBP/EP300 genes in myeloid neoplasia.

CREBBP EP300

4.71e-06276234845315
Pubmed

p300 plays a critical role in maintaining cardiac mitochondrial function and cell survival in postnatal hearts.

CREBBP EP300

4.71e-06276219729597
Pubmed

Nesprins: a novel family of spectrin-repeat-containing proteins that localize to the nuclear membrane in multiple tissues.

SYNE1 SYNE2

4.71e-06276211792814
Pubmed

CREB-binding protein/P300 bromodomain inhibition reduces neutrophil accumulation and activates antitumor immunity in triple-negative breast cancer.

CREBBP EP300

4.71e-06276239287984
Pubmed

Nesprin-1 and nesprin-2 regulate endothelial cell shape and migration.

SYNE1 SYNE2

4.71e-06276224931616
Pubmed

Notch3 inhibits cell proliferation and tumorigenesis and predicts better prognosis in breast cancer through transactivating PTEN.

PTEN NOTCH3

4.71e-06276234006834
Pubmed

Exon deletions of the EP300 and CREBBP genes in two children with Rubinstein-Taybi syndrome detected by aCGH.

CREBBP EP300

4.71e-06276220717166
Pubmed

Mutant huntingtin represses CBP, but not p300, by binding and protein degradation.

CREBBP HTT

4.71e-06276216456924
Pubmed

The epigenetic regulators CBP and p300 facilitate leukemogenesis and represent therapeutic targets in acute myeloid leukemia.

CREBBP EP300

4.71e-06276225893291
Pubmed

Human T-lymphotropic virus type 1 p30(II) regulates gene transcription by binding CREB binding protein/p300.

CREBBP EP300

4.71e-06276211559821
Pubmed

CARM1 inhibition reduces histone acetyltransferase activity causing synthetic lethality in CREBBP/EP300-mutated lymphomas.

CREBBP EP300

4.71e-06276232576962
Pubmed

Syndromic features and mild cognitive impairment in mice with genetic reduction on p300 activity: Differential contribution of p300 and CBP to Rubinstein-Taybi syndrome etiology.

CREBBP EP300

4.71e-06276219822209
Pubmed

A specific CBP/p300-dependent gene expression programme drives the metabolic remodelling in late stages of spermatogenesis.

CREBBP EP300

4.71e-06276224522976
Pubmed

JARID2 regulates epithelial mesenchymal transition through the PTEN/AKT signalling pathways in ovarian endometriosis.

JARID2 PTEN

4.71e-06276236640627
Pubmed

CBP is required for environmental enrichment-induced neurogenesis and cognitive enhancement.

CREBBP EP300

4.71e-06276221847097
Pubmed

p300 or CBP is required for insulin-stimulated glucose uptake in skeletal muscle and adipocytes.

CREBBP EP300

4.71e-06276234813504
Pubmed

Mutant huntingtin represses CBP, but not p300, by binding and protein degradation.

CREBBP HTT

4.71e-06276215994095
Pubmed

Depletion of CBP is directly linked with cellular toxicity caused by mutant huntingtin.

CREBBP HTT

4.71e-06276216766198
Pubmed

Rubinstein-Taybi Syndrome

CREBBP EP300

4.71e-06276220301699
Pubmed

Potential biomarker of metformin action.

CREBBP EP300

4.71e-06276224639469
Pubmed

The histone acetyl transferases CBP and p300 regulate stress response pathways in synovial fibroblasts at transcriptional and functional levels.

CREBBP EP300

4.71e-06276237816914
Pubmed

Binding of p300/CBP co-activators by polyoma large T antigen.

CREBBP EP300

4.71e-06276211438528
Pubmed

Smad-dependent stimulation of type I collagen gene expression in human skin fibroblasts by TGF-beta involves functional cooperation with p300/CBP transcriptional coactivators.

CREBBP EP300

4.71e-06276210918613
Pubmed

Histone Acetyltransferases p300 and CBP Coordinate Distinct Chromatin Remodeling Programs in Vascular Smooth Muscle Plasticity.

CREBBP EP300

4.71e-06276235502657
Pubmed

p300 and cAMP response element-binding protein-binding protein in skeletal muscle homeostasis, contractile function, and survival.

CREBBP EP300

4.71e-06276231898871
Pubmed

Germline or inducible knockout of p300 or CBP in skeletal muscle does not alter insulin sensitivity.

CREBBP EP300

4.71e-06276230888860
Pubmed

Exploitation of EP300 and CREBBP Lysine Acetyltransferases by Cancer.

CREBBP EP300

4.71e-06276227881443
Pubmed

Spatiotemporal expression of histone acetyltransferases, p300 and CBP, in developing embryonic hearts.

CREBBP EP300

4.71e-06276219272189
Pubmed

Differential contribution of p300 and CBP to regulatory element acetylation in mESCs.

CREBBP EP300

4.71e-06276232690000
Pubmed

CBP/p300 antagonises EGFR-Ras-Erk signalling and suppresses increased Ras-Erk signalling-induced tumour formation in mice.

CREBBP EP300

4.71e-06276230953353
Pubmed

Disrupting the CH1 domain structure in the acetyltransferases CBP and p300 results in lean mice with increased metabolic control.

CREBBP EP300

4.71e-06276221803292
Pubmed

HIV-1 tat transactivator recruits p300 and CREB-binding protein histone acetyltransferases to the viral promoter.

CREBBP EP300

4.71e-0627629811832
Pubmed

Two independent regions of simian virus 40 T antigen increase CBP/p300 levels, alter patterns of cellular histone acetylation, and immortalize primary cells.

CREBBP EP300

4.71e-06276224089570
Pubmed

Early alteration of epigenetic-related transcription in Huntington's disease mouse models.

CREBBP HTT

4.71e-06276229967375
Pubmed

Genetic heterogeneity in Rubinstein-Taybi syndrome: mutations in both the CBP and EP300 genes cause disease.

CREBBP EP300

4.71e-06276215706485
Pubmed

AR coactivators, CBP/p300, are critical mediators of DNA repair in prostate cancer.

CREBBP EP300

4.71e-06276239266679
Pubmed

A boy with classical Rubinstein-Taybi syndrome but no detectable mutation in the CREBBP and EP300 genes.

CREBBP EP300

4.71e-06276222303793
Pubmed

Inhibition of histone acetyltransferase function radiosensitizes CREBBP/EP300 mutants via repression of homologous recombination, potentially targeting a gain of function.

CREBBP EP300

4.71e-06276234732714
Pubmed

Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition.

CREBBP EP300

4.71e-06276234019788
Pubmed

Multiple novel nesprin-1 and nesprin-2 variants act as versatile tissue-specific intracellular scaffolds.

SYNE1 SYNE2

4.71e-06276222768332
Pubmed

Endogenous CCAAT/enhancer binding protein beta and p300 are both regulated by growth hormone to mediate transcriptional activation.

CREBBP EP300

4.71e-06276215860545
Pubmed

Further delineation of an entity caused by CREBBP and EP300 mutations but not resembling Rubinstein-Taybi syndrome.

CREBBP EP300

4.71e-06276229460469
Pubmed

Expression of p300 and CBP is associated with poor prognosis in small cell lung cancer.

CREBBP EP300

4.71e-06276224551300
Pubmed

Genome-wide CRISPR screens reveal synthetic lethal interaction between CREBBP and EP300 in diffuse large B-cell lymphoma.

CREBBP EP300

4.71e-06276233911074
Pubmed

The adenovirus 12 E1A proteins can bind directly to proteins of the p300 transcription co-activator family, including the CREB-binding protein CBP and p300.

CREBBP EP300

4.71e-0627629018065
Pubmed

Coactivators p300 and CBP maintain the identity of mouse embryonic stem cells by mediating long-range chromatin structure.

CREBBP EP300

4.71e-06276224648406
Pubmed

CBP and P300 regulate distinct gene networks required for human primary myoblast differentiation and muscle integrity.

CREBBP EP300

4.71e-06276230135524
Pubmed

Distribution of co-activators CBP and p300 during mouse oocyte and embryo development.

CREBBP EP300

4.71e-06276216596650
Pubmed

The p300 and CBP Transcriptional Coactivators Are Required for β-Cell and α-Cell Proliferation.

CREBBP EP300

4.71e-06276229217654
Pubmed

Differences in the interactions of oncogenic adenovirus 12 early region 1A and nononcogenic adenovirus 2 early region 1A with the cellular coactivators p300 and CBP.

CREBBP EP300

4.71e-06276210049825
Pubmed

CBP/p300 acetyltransferase activity in hematologic malignancies.

CREBBP EP300

4.71e-06276227380996
Pubmed

CREBBP and p300 lysine acetyl transferases in the DNA damage response.

CREBBP EP300

4.71e-06276229170789
Pubmed

Crebbp haploinsufficiency in mice alters the bone marrow microenvironment, leading to loss of stem cells and excessive myelopoiesis.

CREBBP EP300

4.71e-06276221555743
Pubmed

Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity.

CREBBP HTT

4.71e-06276211264541
Pubmed

CBP/p300 induction is required for retinoic acid sensitivity in human mammary cells.

CREBBP EP300

4.71e-06276212646247
Pubmed

Syne-1 and Syne-2 play crucial roles in myonuclear anchorage and motor neuron innervation.

SYNE1 SYNE2

4.71e-06276217267447
Pubmed

CHD6 is a DNA-dependent ATPase and localizes at nuclear sites of mRNA synthesis.

CHD3 CHD6

4.71e-06276217027977
Pubmed

Nesprins: tissue-specific expression of epsilon and other short isoforms.

SYNE1 SYNE2

4.71e-06276224718612
Pubmed

Targeted ablation of nesprin 1 and nesprin 2 from murine myocardium results in cardiomyopathy, altered nuclear morphology and inhibition of the biomechanical gene response.

SYNE1 SYNE2

4.71e-06276224586179
Pubmed

Histone acetyltransferase activities of cAMP-regulated enhancer-binding protein and p300 in tissues of fetal, young, and old mice.

CREBBP EP300

4.71e-06276211867645
Pubmed

Expression of the nuclear coactivators CBP and p300 in developing craniofacial tissue.

CREBBP EP300

4.71e-06276211963968
Pubmed

Differential transcriptional activation by human T-cell leukemia virus type 1 Tax mutants is mediated by distinct interactions with CREB binding protein and p300.

CREBBP EP300

4.71e-0627629528808
Pubmed

Analysis of genetic stability at the EP300 and CREBBP loci in a panel of cancer cell lines.

CREBBP EP300

4.71e-06276212696060
Pubmed

Nesprin-1 and -2 are involved in the pathogenesis of Emery Dreifuss muscular dystrophy and are critical for nuclear envelope integrity.

SYNE1 SYNE2

4.71e-06276217761684
Pubmed

CBP Is Required for Establishing Adaptive Gene Programs in the Adult Mouse Brain.

CREBBP EP300

4.71e-06276236109165
Pubmed

Nesprin-1-alpha2 associates with kinesin at myotube outer nuclear membranes, but is restricted to neuromuscular junction nuclei in adult muscle.

SYNE1 SYNE2

4.71e-06276231578382
Pubmed

Retinoids and retinoic acid receptors regulate growth arrest and apoptosis in human mammary epithelial cells and modulate expression of CBP/p300.

CREBBP EP300

4.71e-06276212242694
Pubmed

CBP/p300 Drives the Differentiation of Regulatory T Cells through Transcriptional and Non-Transcriptional Mechanisms.

CREBBP EP300

4.71e-06276231182547
Pubmed

Rubinstein-Taybi syndrome in a Saudi boy with distinct features and variants in both the CREBBP and EP300 genes: a case report.

CREBBP EP300

4.71e-06276230635043
Pubmed

CBP loss cooperates with PTEN haploinsufficiency to drive prostate cancer: implications for epigenetic therapy.

PTEN CREBBP

4.71e-06276224491799
Pubmed

Phenotype and genotype in 52 patients with Rubinstein-Taybi syndrome caused by EP300 mutations.

CREBBP EP300

4.71e-06276227648933
Pubmed

Long-term memory deficits in Huntington's disease are associated with reduced CBP histone acetylase activity.

CREBBP HTT

4.71e-06276222116937
Pubmed

Developmentally regulated expression of the transcriptional cofactors/histone acetyltransferases CBP and p300 during mouse embryogenesis.

CREBBP EP300

4.71e-06276210610021
Pubmed

Emerging roles of p300/CBP in autophagy and autophagy-related human disorders.

CREBBP EP300

4.71e-06276237314181
Pubmed

Distinct roles for CREB-binding protein and p300 in hematopoietic stem cell self-renewal.

CREBBP EP300

4.71e-06276212397173
Pubmed

CBP/p300 TAZ1 domain forms a structured scaffold for ligand binding.

CREBBP EP300

4.71e-06276215641773
Pubmed

Interaction of human immunodeficiency virus type 1 Tat with the transcriptional coactivators p300 and CREB binding protein.

CREBBP EP300

4.71e-0627629733868
Pubmed

Rubinstein-Taybi syndrome in Chinese population with four novel mutations.

CREBBP EP300

4.71e-06276233063428
Pubmed

EP300/CBP is crucial for cAMP-PKA pathway to alleviate podocyte dedifferentiation via targeting Notch3 signaling.

CREBBP EP300

4.71e-06276234506759
Pubmed

Lack of somatic mutations in the catalytic domains of CREBBP and EP300 genes implies a role for histone deacetylase inhibition in myeloproliferative neoplasms.

CREBBP EP300

4.71e-06276222177454
Pubmed

New nomenclature for chromatin-modifying enzymes.

DOT1L KDM4E CREBBP EP300

7.62e-065776418022353
Pubmed

The human T-cell leukemia virus type 1 tax protein confers CBP/p300 recruitment and transcriptional activation properties to phosphorylated CREB.

CREBBP EP300

1.41e-05376218070920
Pubmed

SIRT7 and the DEAD-box helicase DDX21 cooperate to resolve genomic R loops and safeguard genome stability.

DDX21 CREBBP

1.41e-05376228790157
Pubmed

CD103-positive CSC exosome promotes EMT of clear cell renal cell carcinoma: role of remote MiR-19b-3p.

PTEN ITGAE

1.41e-05376230975145
Pubmed

Whole-transcriptome sequencing identifies a distinct subtype of acute lymphoblastic leukemia with predominant genomic abnormalities of EP300 and CREBBP.

CREBBP EP300

1.41e-05376227903646
Pubmed

Inhibition of p300/CBP by early B-cell factor.

CREBBP EP300

1.41e-05376212748286
Pubmed

Genetic interaction between mutations in c-Myb and the KIX domains of CBP and p300 affects multiple blood cell lineages and influences both gene activation and repression.

CREBBP EP300

1.41e-05376224340053
Pubmed

Acetylation of Nrf2 by p300/CBP augments promoter-specific DNA binding of Nrf2 during the antioxidant response.

CREBBP EP300

1.41e-05376219273602
Pubmed

Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila.

CREBBP HTT

1.41e-05376211607033
Pubmed

Activation of Stat3 sequence-specific DNA binding and transcription by p300/CREB-binding protein-mediated acetylation.

CREBBP EP300

1.41e-05376215649887
Pubmed

DUX4 recruits p300/CBP through its C-terminus and induces global H3K27 acetylation changes.

CREBBP EP300

1.41e-05376226951377
Pubmed

CBP/p300 and SIRT1 are involved in transcriptional regulation of S-phase specific histone genes.

CREBBP EP300

1.41e-05376221789216
Pubmed

Mastermind mediates chromatin-specific transcription and turnover of the Notch enhancer complex.

CREBBP EP300

1.41e-05376212050117
Pubmed

Two transactivation mechanisms cooperate for the bulk of HIF-1-responsive gene expression.

CREBBP EP300

1.41e-05376216237459
Pubmed

The IFNgamma-induced STAT1-CBP/P300 association, required for a normal response to the cytokine, is disrupted in Brucella-infected macrophages.

CREBBP EP300

1.41e-05376219041714
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

DRP2 UTRN CREBBP EP300

2.45e-071856491
GeneFamilySpectrin repeat containing nuclear envelope family

SYNE1 SYNE2

5.63e-0545621252
GeneFamilyCD molecules|I-set domain containing|Immunoglobulin like domain containing|Interleukin receptors|TIR domain containing

SARM1 IL1RL2

9.64e-04155621296
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

CREBBP EP300

1.24e-0317562486
CoexpressionGSE17974_2H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_UP

ACOD1 ELOA ELK3 ZSWIM6 DDX21 USP27X PLXNA1

1.62e-06198757M4240
CoexpressionAtlasDevelopingGonad_e16.5_ovary_emap-9563_k-means-cluster#2_top-relative-expression-ranked_1000

LUC7L3 PAFAH1B1 SYNE2 PTEN UTRN CREBBP HTT

1.55e-05230747gudmap_developingGonad_e16.5_ovary_1000_k2
CoexpressionAtlasDevelopingGonad_e12.5_epididymis_emap-29139_k-means-cluster#3_top-relative-expression-ranked_1000

LUC7L3 PAFAH1B1 SYNE2 PTEN UTRN CREBBP HTT

3.32e-05259747gudmap_developingGonad_e12.5_epididymis_k3_1000
CoexpressionAtlasDevelopingGonad_e18.5_epididymis_emap-13166_k-means-cluster#3_top-relative-expression-ranked_1000

LUC7L3 PAFAH1B1 SYNE2 PTEN UTRN CREBBP HTT

5.57e-05281747gudmap_developingGonad_e18.5_epididymis_1000_k3
CoexpressionAtlasalpha beta T cells, T.8Nve.PP, TCR+ CD8+ CD44low CD62Lhigh, Peyer's Patch, avg-1

DZIP1 ITGAE IL2RB UTRN

9.90e-0569744GSM538412_100
CoexpressionAtlasgamma delta T cells, Tgd.vg2+24ahi.Th, TCRd+ Vg2+ CD24+, Thymus, avg-3

TTLL12 RAPGEF3 CHD3 DZIP1 ITGAE IL2RB UTRN MCOLN3

1.11e-04423748GSM476655_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_F-2fold-vs-M_top255_255

ELOA GLI2 SYNE2 CHD3 DZIP1 NOTCH3

1.63e-04233746gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_250_F-2fold-vs-M
ToppCellsevere-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SLC9A4 LUC7L3 SYNE1 SYNE2 CHD3 UTRN

1.11e-0619776657ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c10-MKI67-GZMK|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

FBXW9 ITGAE RWDD2A IL2RB HTT

6.90e-061557655687416773809b8c478567bc54310af102b3029a
ToppCellLeuk-UTI-Lymphocyte-T_NK-gdT|Leuk-UTI / Disease, Lineage and Cell Type

SLC22A9 SYNE1 SYNE2 DZIP1 IL2RB

7.57e-06158765c4b0af25608cee3d0d2b0193f5ff45d9dc87078b
ToppCellChildren_(3_yrs)-Mesenchymal-chondrocyte-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

DZIP1 RWDD2A ARHGEF25 TBL3 NOTCH3

9.91e-06167765f4943fb5001475ddab82a0273bcbb3fa68fdd7bd
ToppCellSevere-Lymphoid-T-|Severe / Condition, Lineage, Cell class and cell subclass

SYNE1 SYNE2 CHD3 ITGAE IL2RB

1.08e-051707655788e1158fde036937d41708e9db3222ca351eb1
ToppCelldroplet-Bladder-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAFAH1B1 SYNE2 CHD3 DDX21 CREBBP

1.71e-05187765663991a8afe652e92363b64bcbd68c14d0307f0e
ToppCellhuman_hepatoblastoma-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

JARID2 LUC7L3 PPP1R9A CHD6 UTRN

1.94e-05192765916fbec1c7ab7969bda711886ac88e877e30c280
ToppCellRA-09._Endothelium_I|RA / Chamber and Cluster_Paper

RAPGEF3 SYNE1 SYNE2 ELK3 UTRN

1.94e-051927658a1b1c3e83a68ad74f8f4eb00455c9e41aa57cfc
ToppCellsevere-low-quality_cells|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SLC9A4 LUC7L3 SYNE1 SYNE2 UTRN

1.99e-051937659337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCellhuman_hepatoblastoma|World / Sample and Cell Type and Tumor Cluster (all cells)

JARID2 LUC7L3 PPP1R9A CHD6 UTRN

1.99e-05193765e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCellRV-09._Endothelium_I|World / Chamber and Cluster_Paper

RAPGEF3 SYNE1 SYNE2 ELK3 UTRN

1.99e-05193765e3fa47e2c7cd8a5b69186711c57751f2296de8ae
ToppCellRV-09._Endothelium_I|RV / Chamber and Cluster_Paper

RAPGEF3 SYNE1 SYNE2 ELK3 UTRN

2.04e-051947657b408096e717f2327c12aea35a8d5fc4621d3b06
ToppCellLV-09._Endothelium_I|World / Chamber and Cluster_Paper

RAPGEF3 SYNE1 SYNE2 ELK3 UTRN

2.09e-0519576519e0a6c3eae1615aaa39767300acd937dfcb2a7f
ToppCellCOVID-19-Heart-EC_1|Heart / Disease (COVID-19 only), tissue and cell type

RAPGEF3 SYNE1 SYNE2 ELK3 UTRN

2.09e-0519576550a193475db1bb1e05b8590225a553688c372c14
ToppCellCOVID-19_Severe-Lymphoid_T/NK-gd_T|COVID-19_Severe / Disease group, lineage and cell class

SYNE1 SYNE2 CHD3 IL2RB UTRN

2.09e-051957659990440bda7fac5d00ef80444fab07459be625e1
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

SYNE1 SYNE2 CHD3 IL2RB UTRN

2.14e-05196765418e8e0a51c5cb60e3b903e7d2d800dc8b9f3d5c
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SYNE1 SYNE2 CHD3 IL2RB UTRN

2.14e-05196765581fc8c8d42005aacd7b401a2c9d1fc331fb4af7
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ACOD1 JARID2 CSGALNACT2 DOT1L EP300

2.14e-05196765c2bbb48c4aa979b03cb6f4ce9f351f492977c992
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ACOD1 JARID2 CSGALNACT2 DOT1L EP300

2.14e-0519676564c2abc0087bf2ae547932377f3662e3be1cc63e
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SYNE1 SYNE2 CHD3 IL2RB UTRN

2.14e-051967656beaf0c2799424c59819b286fbb5c1a83d85e4d1
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SYNE1 SYNE2 CHD3 IL2RB UTRN

2.14e-05196765c35f2349dfe35baa845f790b9f31673dceac54c0
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PLB1 LUC7L3 SYNE2 MROH5 UTRN

2.20e-05197765b94645d57efe8d9e032bffb8c89af1f425c6421e
ToppCellCOVID_vent-Lymphocytic-T_cell-CD8+_Memory_T_cell|COVID_vent / Disease condition, Lineage, Cell class and subclass

SYNE1 SYNE2 CHD3 IL2RB UTRN

2.20e-05197765d4dfb3b561d0783cdbee4e8d27009ad81df695cb
ToppCell10x_3'_v3-blood_(10x_3'_v3)-lymphocytic-T_lymphocytic-CD8-positive,_alpha-beta_cytokine_secreting_effector_T_cell|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SYNE1 PPP1R9A SYNE2 IL2RB UTRN

2.25e-0519876534c564ece9a2b94dcf646e3c95b5be9c5ecfaafe
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

CDKL5 LUC7L3 SYNE2 UTRN PLXNA1

2.30e-05199765d43c605a4ff221cf78d91678c15d2ad20f831c7f
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_submucosal-gland-SMG_Serous|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

PPP1R9A SARM1 IL1RL2 ZNF891 MCOLN3

2.36e-0520076561bae10c8b12196d9cee766897971b81cb897191
ToppCellhealthy_donor|World / Disease condition, Lineage, Cell class and subclass

LUC7L3 SYNE1 SYNE2 IL2RB UTRN

2.36e-05200765afd4d5609adaa470e3d880f8be4a4d55e162b3d6
ToppCellCOVID-19-COVID-19_Severe-Lymphocyte-T/NK-gd_T|COVID-19_Severe / Disease, condition lineage and cell class

SYNE1 SYNE2 CHD3 IL2RB UTRN

2.36e-05200765f72bc3f6606ae77fe1b0a972e35b3ce0727804d9
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-like|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BCO2 TLL2 CPVL TF

8.17e-0513476464979e1a056b7406e1be39c5ebe2f8d731ac3c17
ToppCellEnterocyte-C_02|Enterocyte / shred on cell type and cluster

LUC7L3 CHD6 DDX21 UTRN

8.66e-05136764daf11618c65e8fa2d77001b5c277d534cc012a4b
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC9A4 DRP2 MORN5 NOTCH3

1.33e-04152764d5ba87b5d34e52cef8475befafea962d70fa8a1d
ToppCelldroplet-Liver-LIVER_HEPATOCYTES|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC9A4 DRP2 MORN5 NOTCH3

1.33e-04152764d88d68a788a3256671ebbc06e104833f1f58f07d
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DRP2 SARM1 IL2RB IL1RL2

1.33e-041527643951a9f5fe164002311ed2ef7c36ae958451826b
ToppCellLPS_only-Epithelial_airway-Ciliated_cells-Ciliated|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLC9A4 ADGRA1 DNAH9 MORN5

1.40e-041547649ca71d440c4f87781e6525b8141e7d8d470b6a8e
ToppCellLPS_only-Epithelial_airway-Ciliated_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLC9A4 ADGRA1 DNAH9 MORN5

1.40e-0415476458072ce422d09f2de602580325eaac6c4ec6c136
ToppCell10x5'-Lung-Lymphocytic_T_CD4-T_CD4/CD8|Lung / Manually curated celltypes from each tissue

CFAP47 SYNE2 ARHGEF25 DNAH9

1.47e-0415676410d191e29b16cae8238e8df6c0ff38882253f34e
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FBXW9 MON1A CAPN15 WDR47

1.58e-041597649f6607e395bcca9cb1c83199bdbbaaa62a93938d
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FBXW9 MON1A CAPN15 WDR47

1.58e-04159764c8b42ebc25ebcc450832096fbffaa5c5f5fe88e7
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRHDE PLB1 CPVL DNAH9

1.62e-04160764c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRHDE PLB1 CPVL DNAH9

1.62e-0416076425c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TRHDE TTLL12 TMEM144 SYNE2

1.66e-041617645fba13f0aa5002f7eefe219e2c6a07e163f1a50d
ToppCellnormal-na-Lymphocytic_NK-NK_bright-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

SYNE1 PPP1R9A IL2RB UTRN

1.78e-04164764b5a91f2cbfad9a2bc38aea576085a37865df955d
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-Klrb1a/b/c(-)_NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DRP2 SYNE1 CHD3 IL2RB

1.82e-04165764eeb58d4db64ad37dc6b441eab22b05c24862e1a9
ToppCelldroplet-Mammary_Gland-nan-21m-Epithelial-nan|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTLL12 LRRCC1 DZIP1 DDC

1.82e-041657647c771f22b58989572c939ed127e637ec28dc0dca
ToppCellCiliated_cells-B-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

CFAP47 BCO2 DNAH9 MORN5

1.86e-041667644b1056aad8a99827835242b8ab0c7f2bb84471f1
ToppCelldroplet-Thymus-nan-3m-Lymphocytic-DN4|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHD3 ITGAE IL2RB UTRN

1.91e-0416776410c9fab3573c2948081aac2cec1798e46e59e38a
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-T_cells-TRGV5/7_gdT|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CCDC71 USP27X IL2RB ZMYND12

1.91e-0416776418e336faa2d2429ab49d1c6ae9bbf9923d74aa8d
ToppCell10x5'-Lung-Lymphocytic_T_CD4/8-lo-Trm_Tgd|Lung / Manually curated celltypes from each tissue

DNHD1 BCO2 ITGAE IL2RB

1.91e-04167764dcbcc658082910838c8082d71a64917055086cc4
ToppCell3'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(NPW+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADGRA1 DDC UNC13A MCOLN3

1.95e-041687644e1b522c7400c9d87f63c00e4e1dd07136095cd6
ToppCell3'-GW_trimst-1-SmallIntestine-Epithelial-neuro-epithelial-L_cells_(PYY+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NTS ADGRA1 DDC MCOLN3

1.95e-041687640f736d58cb0ff042fa3ce58e36bde37b6976f8fc
ToppCelldroplet-Thymus-nan-3m-Lymphocytic-DN4_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHD3 ITGAE IL2RB UTRN

2.00e-041697642de213b083f57f47be58427c0ce127fee9f85caa
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC9A4 RAPGEF3 PPP1R9A CHD3

2.04e-04170764928e42c51a7079c506f21c669c4e4c1a0df84d77
ToppCellnormal-na-Lymphocytic_NK-natural_killer_cell-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

SYNE1 PPP1R9A SYNE2 IL2RB

2.09e-04171764d339840626211a7bf1a9eb8f14d6c9509ab05e1c
ToppCellTracheal-10x3prime_v2-Immune_Myeloid-Macrophage_other-Macrophage_intermediate|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

JARID2 CSGALNACT2 EP300

2.15e-0468763f1cbc6d72489272c1eb6200f64b8b6444719acda
ToppCellBrain_organoid-organoid_Tanaka_cellReport-5w-Mesenchymal-Cilia-bearing_cell|5w / Sample Type, Dataset, Time_group, and Cell type.

TTLL12 CDKL5 ARHGEF25 MORN5

2.18e-04173764d4cbeae262abfa30d8c5452285d3261a96875610
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TLL2 SARM1 TBL3 CAPN15

2.18e-0417376423e50492bc673aff9df95d97f0b9be4ce57cbf01
ToppCelldroplet-Spleen-nan-24m-Lymphocytic-T_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHD3 ITGAE IL2RB UTRN

2.23e-04174764919fc124affc69acfd8f575f2c372674f3d2625e
ToppCelldroplet-Lung-1m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SARM1 ITGAE IL2RB DDC

2.28e-04175764c38525583962c0e14130f4c98de912d8747bc4cb
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRHDE SYNE1 CPVL UTRN

2.33e-04176764327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCellHippocampus|World / BrainAtlas - Mouse McCarroll V32

SLC9A4 RWDD2A ARHGEF25 DNAH9

2.33e-04176764f120a703f6d2f2d5f55eae1aea2e6382a485828f
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP47 DNAH9 NOTCH3 ZMYND12

2.38e-04177764e8bb4f8ecd5e283efec966b9fc2040a6152d5551
ToppCellfacs-Trachea-3m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell-ciliated_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CFAP47 DNAH9 MORN5 ZMYND12

2.38e-041777643cfde67b93f3986312f5e74e42504214d966e7dc
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRHDE SYNE1 CPVL UTRN

2.38e-04177764da8802a6351d3e510822f82e2fde8a4314a2216e
ToppCellfacs-Trachea-3m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CFAP47 DNAH9 MORN5 ZMYND12

2.38e-0417776412a52a12a87a31e501ced611f46a90d172ca7e35
ToppCellfacs-Heart-RV-18m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLXNA1 UNC13A CRHR2 NOTCH3

2.38e-041777647c3d46ebd7e8726be6871aa9763e281fc0ec6ac8
ToppCellfacs-Heart-RV-18m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLXNA1 UNC13A CRHR2 NOTCH3

2.38e-04177764e7b1f3092e6b8d0d580f82648035f5ad12be6961
ToppCelldroplet-Marrow-nan-3m-Hematologic-hematopoietic_precursor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHD3 DDX21 IL2RB UTRN

2.43e-041787648aef208b6351143562c87715bb11628880abce94
ToppCellMid-temporal_gyrus_(MTG)|World / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC22A9 LUC7L3 CHD3 PLXNA1

2.43e-04178764ad187db4c40b9078d54dd915c143e0172b2f47b8
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-ependymal_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRHDE CFAP47 DNAH9 ZMYND12

2.43e-04178764b1db59344c074c7c80169fc2c5cd5fc89f3fe463
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-Ependyma|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRHDE CFAP47 DNAH9 ZMYND12

2.43e-04178764579cdc14f28b459e200ae2102e0bd4df8a2c0dcb
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADGRA1 DDC UNC13A MCOLN3

2.49e-04179764d70791d2a0db35a6b013fa7ed2f9f39364581eff
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L5-6_SST_TH|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TRHDE TLL2 UTRN DDC

2.49e-04179764797d165718dd1d819e65add3a7859f87b32238a5
ToppCellCiliated_cells-B-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

CFAP47 ADGRA1 DNAH9 MORN5

2.54e-04180764bdea5ec6b60fc8c7cce4d71db5da74ac8675e211
ToppCelldroplet-Heart-nan-3m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAPGEF3 SYNE2 ELK3 UTRN

2.59e-0418176492d44892bb15771f0ab5fe61879b204b0acbd9b3
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK-NK_bright-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SYNE1 PPP1R9A IL2RB UTRN

2.59e-041817649c4f9abb9335da2b07644bca8faff1baa1bb9f5b
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(NPW+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADGRA1 DDC UNC13A MCOLN3

2.59e-041817642392af8c7f040c23a7d416c2e37419954970c8f4
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADGRA1 DDC UNC13A MCOLN3

2.65e-041827640e589bf97d51b4b2f723f8c45853ad81b7ce8778
ToppCelldroplet-Heart-nan-3m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAPGEF3 SYNE2 ELK3 UTRN

2.65e-0418276481279877b920b5a1bc991a07d3031d6458700fe3
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TMEM144 RAPGEF3 PLD1 TF

2.70e-041837645472cdce6d99314d229418412acf1fff6340db7d
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TMEM144 RAPGEF3 PLD1 TF

2.76e-041847645939527d24d299e562e707469c9123890edd76be
ToppCellCOPD-Myeloid-cMonocyte|World / Disease state, Lineage and Cell class

JARID2 ZSWIM6 PTEN IL1RL2

2.76e-04184764ceec41ed5636032aaf7716d1203816ea58bd39bd
ToppCellnormal-na-Lymphocytic_NK-NK_dim-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

SYNE1 SYNE2 IL2RB UTRN

2.82e-04185764b1a8a8c4d0fc7605eabc17dcb6bd9e8ab4fd578c
ToppCellBAL-Mild-cDC_12|Mild / Compartment, Disease Groups and Clusters

BCO2 TOPBP1 RWDD2A USP27X

2.82e-04185764e867ed55ab0df018f14bca824da09d36d83e12f9
ToppCellAnterior_Cingulate_gyrus_(CgG)|World / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LUC7L3 STAG3L1 STAG3L2 STAG3L3

2.88e-0418676432af3f211f9ad5d5c6b86b83325cfbf2f8466b56
ToppCellASK440-Immune-NK_cell|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq

SYNE1 SYNE2 POLN IL2RB

2.88e-04186764ce8e63057a99afa0a9cbf27ae7f9a70c0e972b6d
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK-NK_dim-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SYNE1 SYNE2 IL2RB UTRN

2.94e-041877640bca79cea4886b66350c56c61859bd71e1e7a85c
ToppCellCOVID-NK-|COVID / Condition, Cell_class and T cell subcluster

SYNE1 PPP1R9A IL2RB UTRN

3.00e-04188764fabdd68a9734d35e75e1f4a4bfd5c531cfc099f1
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRHDE SYNE1 CPVL UTRN

3.00e-0418876463a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCellCOPD-Multiplet-Multiplet|World / Disease state, Lineage and Cell class

SYNE1 SYNE2 IL2RB DNAH9

3.00e-04188764186fe1ea328c942910190a4240262c0d8642ea3b
ToppCellCOVID-NK|COVID / Condition, Cell_class and T cell subcluster

SYNE1 PPP1R9A IL2RB UTRN

3.00e-041887640beaa671611110a11e46156f54f5202cc24967a4
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK-NK_bright|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SYNE1 PPP1R9A IL2RB UTRN

3.06e-041897643e148accffc6ab249fb0dff7f3bf5a7fff9da773
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE1 SYNE2 CPVL UTRN

3.12e-04190764b855b8b7d3439023390ca44629c1a99f5d4c6801
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.4.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SYNE1 SYNE2 IL2RB UTRN

3.12e-04190764d153a0bdedcd6865e6ee19575234a78b5d859ff1
ToppCellCOVID-19-Heart-EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

SYNE2 PTEN UTRN NOTCH3

3.12e-04190764a21653bfb7bafbc273f94fa7c13bfb48cf8fd562
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE1 SYNE2 CPVL UTRN

3.12e-04190764a5db902ad112a0c0a0a7f1a2e38718bb3bd11412
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CFAP47 SLC9A4 RAPGEF3 PPP1R9A

3.12e-04190764078f4be52fa4cc8dd9c8d7a2b6d9631c3d902285
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ACOD1 JARID2 CSGALNACT2 DOT1L

3.18e-041917640b296404ebad0aadb75737f8c0462ec6934fc8bb
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

GLI2 UTRN UNC13A NOTCH3

3.18e-0419176404c4d454b57e29a8d1dcdeb4678ce71bdc29b77b
ToppCellControl-Lymphoid_T/NK-NK_CD56bright|Control / Disease group, lineage and cell class

SYNE1 PPP1R9A IL2RB UTRN

3.18e-04191764e842f29bc03ed6734b2a7b975e7830a498f2743c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GLI2 PTEN UTRN NOTCH3

3.18e-041917647b0d42a877540dbb346a76a62403e0d5d3e07fa6
DiseaseRUBINSTEIN-TAYBI SYNDROME 1

CREBBP EP300

6.04e-062732180849
DiseaseRubinstein-Taybi syndrome due to CREBBP mutations

CREBBP EP300

6.04e-062732cv:C4551859
DiseaseMenke-Hennekam syndrome

CREBBP EP300

6.04e-062732cv:C5681632
DiseaseRubinstein-Taybi syndrome (implicated_via_orthology)

CREBBP EP300

6.04e-062732DOID:1933 (implicated_via_orthology)
DiseaseRubinstein-Taybi syndrome

CREBBP EP300

6.04e-062732cv:C0035934
DiseaseRUBINSTEIN-TAYBI SYNDROME 1

CREBBP EP300

6.04e-062732C4551859
DiseaseRubinstein-Taybi syndrome (is_implicated_in)

CREBBP EP300

6.04e-062732DOID:1933 (is_implicated_in)
DiseaseRubinstein-Taybi Syndrome

CREBBP EP300

6.04e-062732C0035934
DiseaseAutosomal dominant Emery-Dreifuss muscular dystrophy

SYNE1 SYNE2

3.61e-054732cv:CN293514
DiseaseSezary Syndrome

CHD3 PTEN CREBBP

4.07e-0527733C0036920
DiseaseAutosomal Recessive Emery-Dreifuss Muscular Dystrophy

SYNE1 SYNE2

6.01e-055732C1450051
DiseaseAutosomal Dominant Emery-Dreifuss Muscular Dystrophy (disorder)

SYNE1 SYNE2

6.01e-055732C0410190
DiseaseEmery-Dreifuss muscular dystrophy

SYNE1 SYNE2

9.00e-056732cv:C0410189
DiseaseMuscular Dystrophy, Emery-Dreifuss

SYNE1 SYNE2

9.00e-056732C0410189
DiseaseAdenoid Cystic Carcinoma

STAG3L1 PTEN CREBBP EP300

1.13e-04100734C0010606
Diseaseceroid-lipofuscinosis neuronal protein 5 measurement

ACOD1 SARM1

1.26e-047732EFO_0802390
DiseaseX-Linked Emery-Dreifuss Muscular Dystrophy

SYNE1 SYNE2

1.26e-047732C0751337
DiseaseCarcinoma, Transitional Cell

CHD6 CREBBP EP300

1.45e-0441733C0007138
DiseaseHuntington's disease (is_marker_for)

PPP1R9A CREBBP HTT

3.11e-0453733DOID:12858 (is_marker_for)
Diseaseinterleukin 1 receptor-like 1 measurement

SLC9A4 IL1RL2

3.27e-0411732EFO_0008168
DiseaseMacrocephaly

CHD3 PTEN

3.27e-0411732C0221355
Diseaseserum ST2 measurement

SLC9A4 IL1RL2

3.27e-0411732EFO_0005416
DiseaseSmall cell carcinoma of lung

PTEN CREBBP EP300

3.29e-0454733C0149925
DiseaseEmery-Dreifuss muscular dystrophy (implicated_via_orthology)

SYNE1 SYNE2

3.92e-0412732DOID:11726 (implicated_via_orthology)
Diseasebiliary atresia (is_marker_for)

GLI2 PTEN

5.39e-0414732DOID:13608 (is_marker_for)
Diseaseinterleukin 18 receptor 1 measurement

SLC9A4 IL1RL2

6.21e-0415732EFO_0008178
DiseaseIntellectual Disability

SYNE1 CHD3 PTEN ACBD6 USP27X HTT

8.45e-04447736C3714756
Diseaseglomerulonephritis (is_marker_for)

TF EP300

1.00e-0319732DOID:2921 (is_marker_for)
DiseaseMalignant neoplasm of breast

SLC22A9 SYNE1 SYNE2 ELK3 PTEN RUFY1 DNAH9 EP300 NOTCH3

1.30e-031074739C0006142
DiseaseNasopharyngeal carcinoma

SYNE1 PTEN

1.35e-0322732C2931822
Diseasealcohol use disorder (implicated_via_orthology)

CREBBP EP300 UNC13A NOTCH3

1.41e-03195734DOID:1574 (implicated_via_orthology)
DiseaseSquamous cell carcinoma of esophagus

CREBBP EP300 NOTCH3

1.71e-0395733C0279626
DiseaseAdenocarcinoma of lung (disorder)

DOT1L TF CREBBP EP300

1.72e-03206734C0152013
Diseasebipolar disorder (is_implicated_in)

SYNE1 DDC

2.35e-0329732DOID:3312 (is_implicated_in)
Diseasehepatocellular carcinoma (biomarker_via_orthology)

PPP1R9A PTEN EP300

2.46e-03108733DOID:684 (biomarker_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
CHNSSDRIKVRVWDE

UNC13A

731

Q9UPW8
EAIIWVSNKSEHHRI

TRHDE

656

Q9UKU6
NECKHHVETRWHCTV

EP300

1671

Q09472
WLDHSKHCLSVETEA

ARHGEF25

81

Q86VW2
FVLIHHCAKREDVWQ

ADGRA1

301

Q86SQ6
KHHVETRWHCTVCED

CREBBP

1711

Q92793
KVQEFCREHHWITGI

DNHD1

706

Q96M86
HDAAHEIIETIRWVC

DOT1L

31

Q8TEK3
LHWACDRGHKELVTV

ACBD6

196

Q9BR61
ESAHVQRAWEHIKEL

DDC

456

P20711
WCSHENLHQEDLEKE

BCO2

446

Q9BYV7
HFCDIRHLDDWAKSQ

POLN

196

Q7Z5Q5
DVTNRKSFEHIQDWH

RAB42

96

Q8N4Z0
ELREHEHVVECISWA

PAFAH1B1

271

P43034
SVDICKVHSDWQEAR

CAPN15

786

O75808
VCHALRDLVSDHVTW

FBXW9

106

Q5XUX1
DNDISIRECKDWHVS

MCOLN3

261

Q8TDD5
CHECIEHIRKQNWFE

CPVL

271

Q9H3G5
VQHVEEWHSVSCVIA

ITGAE

1046

P38570
IHDADVRHTWKSNCL

PLXNA1

1731

Q9UIW2
AEEAVDCRQWTQHHL

NOTCH3

1741

Q9UM47
DCRQWTQHHLVAADI

NOTCH3

1746

Q9UM47
LVDHEVHESNEVWCR

CRHR2

171

Q13324
ELWKHRQDLAIVEHT

KDM4E

331

B2RXH2
DEKRSNVRWDHESVC

LUC7L3

21

O95232
EHIHGEKKEFVCRWQ

GLI2

461

P10070
VSAKDCVHVHLDLTW

OTOP2

156

Q7RTS6
IHVNLTVFEKHWCDT

IL1RL2

106

Q9HB29
EAWRLHQKHVFVLSE

MON1A

246

Q86VX9
CHSRAFQHWELIQED

NTS

111

P30990
QHVEEKAVHSWSRIS

CCDC71

6

Q8IV32
LFHLWHEKRCADELT

CSGALNACT2

481

Q8N6G5
VCQNLHDSEHLTWLI

HTT

1906

P42858
IEETDQLWKVHCHRD

ELOA

626

Q14241
QLWKVHCHRDFKEER

ELOA

631

Q14241
HWSCVIIDEAHRLKN

CHD6

591

Q8TD26
HCSWAKELQLEIFHL

CHD3

561

Q12873
VHVETHRCNISWEIS

IL2RB

141

P14784
LDQKHEHLICWTSND

ELK3

16

P41970
HWVADAAASVRKHLV

ACOD1

281

A6NK06
RHRWDDEVKHCFANI

DNAH9

1811

Q9NYC9
VEHLAIKCHWTQRAA

DDX21

411

Q9NR30
KAIHWCHKNDIVHRD

CDKL5

121

O76039
ENTRHVIWKNCHKDV

CFAP47

1761

Q6ZTR5
KTTCENWREIHHLVF

BVES

31

Q8NE79
LWEKLTARCVDQHRH

DRP2

211

Q13474
WLSEDDNHVAAIHCK

PTEN

111

P60484
WRLVEEKDCHVAVHC

JARID2

851

Q92833
ICRHSWRVVAQHLET

MROH5

196

Q6ZUA9
HQLDEIICWLTKAEH

UTRN

2091

P46939
DELNSHEHELCWLKD

SYNE1

2026

Q8NF91
DVCAKWESLHHELSL

SYNE2

921

Q8WXH0
WAHHEKLVIIDQSVA

PLD1

461

Q13393
GHRCWVHILDNDTVS

SLC22A9

46

Q8IVM8
GHAWLKDDEATHCRQ

RUFY1

636

Q96T51
EDVCGHWSHYQVRDK

SLC9A4

506

Q6AI14
WTLHDKHREVRVKCV

STAG3L1

51

P0CL83
DHRVNFHEDWKVITV

PLB1

841

Q6P1J6
WKHISCKHAESVETE

RWDD2A

216

Q9UIY3
ESKWTARVQAIHQEH

DZIP1

371

Q86YF9
CHVKHDWAFQDRDAQ

RAPGEF3

166

O95398
EHKDKVIQCRWHTQD

WDR47

886

O94967
RHHKDQWFKCDDAVI

USP27X

386

A6NNY8
LSHHERLKCDEWSVN

TF

366

P02787
QDHDCKDWVHKEIVT

SARM1

631

Q6SZW1
WVDKLSTVHHRIVGC

TMEM144

176

Q7Z5S9
LDAHEDKVWGLHCSR

TBL3

601

Q12788
DKVWGLHCSRLDDHA

TBL3

606

Q12788
HWEKHTCVTFIERTD

TLL2

186

Q9Y6L7
WTLHDKHREVRVKCV

STAG3L2

51

P0CL84
DHAWTCRVEHARQQL

TTLL12

121

Q14166
HQKADWDSIHEKICQ

ZMYND12

41

Q9H0C1
TRAIEACDLHWQDSH

ZSWIM6

516

Q9HCJ5
WTLHDKHREVRVKCV

STAG3L3

51

P0CL85
VHIVSEHWLLDCAQE

TOPBP1

966

Q92547
HLELKHFAEAVNWCD

TTC4

161

O95801
TLREDWECHKIRKQH

ZNF891

151

A8MT65
ADDDEHEWITRTCRK

MORN5

146

Q5VZ52
HCNNISKIEAIDHIW

LRRCC1

51

Q9C099
WIEAQTLCHTVNEHL

PPP1R9A

736

Q9ULJ8