Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	L27 domain binding	LIN7C LIN7A LIN7B	4.29e-07	4	96	3	GO:0097016
GeneOntologyMolecularFunction	calcium ion binding	MYL3 MYL6 DSG1 ENPP2 MATN1 FKBP9 CRELD2 AIF1L PKDREJ SVEP1 RYR2 ITPR3 PPP2R3A CELSR1 ATP2B2	2.76e-06	749	96	15	GO:0005509
GeneOntologyMolecularFunction	oxo-acid-lyase activity	CLYBL TYW1B TYW1	3.72e-06	7	96	3	GO:0016833
GeneOntologyMolecularFunction	tRNA-4-demethylwyosine synthase activity	TYW1B TYW1	2.29e-05	2	96	2	GO:0102521
GeneOntologyMolecularFunction	H3K27me3 modified histone binding	TAF1 TAF1L	2.27e-04	5	96	2	GO:0061628
GeneOntologyBiologicalProcess	protein localization to basolateral plasma membrane	LIN7C LIN7A LIN7B	5.55e-06	8	97	3	GO:1903361
GeneOntologyBiologicalProcess	maintenance of epithelial cell apical/basal polarity	LIN7C LIN7A LIN7B	1.62e-05	11	97	3	GO:0045199
GeneOntologyBiologicalProcess	maintenance of apical/basal cell polarity	LIN7C LIN7A LIN7B	2.15e-05	12	97	3	GO:0035090
GeneOntologyBiologicalProcess	cardiac muscle tissue morphogenesis	COL11A1 MYL3 UBE4B RYR2 MYLK2	3.13e-05	77	97	5	GO:0055008
GeneOntologyBiologicalProcess	cell adhesion mediated by integrin	EMILIN2 ITGAD ITGAE WNK1 EPHA2	7.00e-05	91	97	5	GO:0033627
GeneOntologyBiologicalProcess	muscle tissue morphogenesis	COL11A1 MYL3 UBE4B RYR2 MYLK2	7.77e-05	93	97	5	GO:0060415
GeneOntologyBiologicalProcess	maintenance of cell polarity	LIN7C LIN7A LIN7B	1.08e-04	20	97	3	GO:0030011
GeneOntologyBiologicalProcess	cardiac ventricle development	COL11A1 MYL3 UBE4B RYR2 SCN5A HECTD1	1.13e-04	161	97	6	GO:0003231
GeneOntologyBiologicalProcess	muscle organ morphogenesis	COL11A1 MYL3 UBE4B RYR2 MYLK2	1.20e-04	102	97	5	GO:0048644
GeneOntologyBiologicalProcess	ventricular cardiac muscle tissue morphogenesis	COL11A1 MYL3 UBE4B RYR2	1.72e-04	59	97	4	GO:0055010
GeneOntologyBiologicalProcess	cell-matrix adhesion	ENPP2 ITGAD ITGAE HPSE RCC2 SVEP1 CTTN	2.87e-04	270	97	7	GO:0007160
GeneOntologyBiologicalProcess	wybutosine metabolic process	TYW1B TYW1	3.24e-04	6	97	2	GO:0031590
GeneOntologyBiologicalProcess	wybutosine biosynthetic process	TYW1B TYW1	3.24e-04	6	97	2	GO:0031591
GeneOntologyBiologicalProcess	Purkinje myocyte to ventricular cardiac muscle cell communication	RYR2 SCN5A	3.24e-04	6	97	2	GO:0086068
GeneOntologyBiologicalProcess	Purkinje myocyte to ventricular cardiac muscle cell signaling	RYR2 SCN5A	3.24e-04	6	97	2	GO:0086029
GeneOntologyBiologicalProcess	actin-mediated cell contraction	MYL6 RYR2 MYLK2 SCN1A SCN5A	3.35e-04	127	97	5	GO:0070252
GeneOntologyCellularComponent	MPP7-DLG1-LIN7 complex	LIN7C LIN7A LIN7B	9.32e-07	5	96	3	GO:0097025
GeneOntologyCellularComponent	tight junction	LIN7C CYTH2 LIN7A LIN7B MAGI2 EPHA2	4.40e-05	139	96	6	GO:0070160
GeneOntologyCellularComponent	cell-cell junction	LIN7C DSG1 CYTH2 LIN7A ABCB4 LIN7B MAGI2 EPHA2 SCN1A SCN5A PDZD2	8.43e-05	591	96	11	GO:0005911
GeneOntologyCellularComponent	anchoring junction	LIN7C DSG1 CYTH2 AIF1L PPIB LIN7A ABCB4 LIN7B MAGI2 EPHA2 SCN1A SCN5A CTTN PDZD2	1.43e-04	976	96	14	GO:0070161
GeneOntologyCellularComponent	collagen type XI trimer	COL2A1 COL11A1	2.07e-04	5	96	2	GO:0005592
GeneOntologyCellularComponent	bicellular tight junction	LIN7C CYTH2 LIN7A LIN7B MAGI2	3.47e-04	131	96	5	GO:0005923
GeneOntologyCellularComponent	apical junction complex	LIN7C CYTH2 LIN7A LIN7B MAGI2	8.14e-04	158	96	5	GO:0043296
MousePheno	ventricular fibrillation	RYR2 SCN1A SCN5A	4.91e-06	7	74	3	MP:0006110
MousePheno	fibrillation	RYR2 SCN1A SCN5A	4.97e-05	14	74	3	MP:0006109
Domain	L27_C	LIN7C LIN7A LIN7B	1.35e-05	10	92	3	IPR014775
Domain	L27	LIN7C LIN7A LIN7B	1.35e-05	10	92	3	PF02828
Domain	TAF_II_230-bd	TAF1 TAF1L	2.40e-05	2	92	2	IPR009067
Domain	TFIID_sub1_DUF3591	TAF1 TAF1L	2.40e-05	2	92	2	IPR022591
Domain	-	TAF1 TAF1L	2.40e-05	2	92	2	1.10.1100.10
Domain	tRNA_wybutosine-synth	TYW1B TYW1	2.40e-05	2	92	2	IPR013917
Domain	TBP-binding	TAF1 TAF1L	2.40e-05	2	92	2	PF09247
Domain	DUF3591	TAF1 TAF1L	2.40e-05	2	92	2	PF12157
Domain	Wyosine_form	TYW1B TYW1	2.40e-05	2	92	2	PF08608
Domain	TAF1_animal	TAF1 TAF1L	2.40e-05	2	92	2	IPR011177
Domain	L27	LIN7C LIN7A LIN7B	3.19e-05	13	92	3	SM00569
Domain	L27	LIN7C LIN7A LIN7B	3.19e-05	13	92	3	PS51022
Domain	L27_dom	LIN7C LIN7A LIN7B	3.19e-05	13	92	3	IPR004172
Domain	VWA	MATN1 ITGAD ITGAE SVEP1	1.66e-04	56	92	4	PF00092
Domain	RIH_assoc	RYR2 ITPR3	3.55e-04	6	92	2	PF08454
Domain	RIH_assoc-dom	RYR2 ITPR3	3.55e-04	6	92	2	IPR013662
Domain	RIH_dom	RYR2 ITPR3	3.55e-04	6	92	2	IPR000699
Domain	Na_trans_cytopl	SCN1A SCN5A	3.55e-04	6	92	2	PF11933
Domain	Ins145_P3_rcpt	RYR2 ITPR3	3.55e-04	6	92	2	IPR014821
Domain	Ryanodine_recept-rel	RYR2 ITPR3	3.55e-04	6	92	2	IPR015925
Domain	-	RYR2 ITPR3	3.55e-04	6	92	2	1.25.10.30
Domain	RYDR_ITPR	RYR2 ITPR3	3.55e-04	6	92	2	PF01365
Domain	Ins145_P3_rec	RYR2 ITPR3	3.55e-04	6	92	2	PF08709
Domain	Na_trans_cytopl	SCN1A SCN5A	3.55e-04	6	92	2	IPR024583
Domain	EF-hand-dom_pair	MYL3 MYL6 FKBP9 AIF1L RYR2 PPP2R3A SCN1A	5.41e-04	287	92	7	IPR011992
Domain	FLAVODOXIN_LIKE	TYW1B TYW1	6.59e-04	8	92	2	PS50902
Domain	Flavodoxin/NO_synth	TYW1B TYW1	6.59e-04	8	92	2	IPR008254
Domain	Flavdoxin-like	TYW1B TYW1	6.59e-04	8	92	2	IPR001094
Domain	Flavodoxin_1	TYW1B TYW1	6.59e-04	8	92	2	PF00258
Domain	PDZ	LIN7C LIN7A LIN7B MAGI2 PDZD2	6.63e-04	141	92	5	PF00595
Domain	VWFA	MATN1 ITGAD ITGAE SVEP1	7.19e-04	82	92	4	PS50234
Domain	VWA	MATN1 ITGAD ITGAE SVEP1	7.87e-04	84	92	4	SM00327
Domain	PDZ	LIN7C LIN7A LIN7B MAGI2 PDZD2	8.26e-04	148	92	5	SM00228
Domain	rSAM	TYW1B TYW1	8.45e-04	9	92	2	IPR007197
Domain	Radical_SAM	TYW1B TYW1	8.45e-04	9	92	2	PF04055
Domain	-	LIN7C LIN7A LIN7B MAGI2 PDZD2	8.77e-04	150	92	5	2.30.42.10
Domain	PDZ	LIN7C LIN7A LIN7B MAGI2 PDZD2	9.03e-04	151	92	5	PS50106
Domain	EF-hand_1	MYL3 MYL6 FKBP9 RYR2 PPP2R3A	9.31e-04	152	92	5	PF00036
Domain	PDZ	LIN7C LIN7A LIN7B MAGI2 PDZD2	9.31e-04	152	92	5	IPR001478
Domain	EF_HAND_2	MYL3 MYL6 FKBP9 AIF1L RYR2 PPP2R3A	9.87e-04	231	92	6	PS50222
Domain	EF_hand_dom	MYL3 MYL6 FKBP9 AIF1L RYR2 PPP2R3A	1.01e-03	232	92	6	IPR002048
Domain	Na_channel_asu	SCN1A SCN5A	1.05e-03	10	92	2	IPR001696
Domain	MIR	RYR2 ITPR3	1.05e-03	10	92	2	PS50919
Domain	MIR	RYR2 ITPR3	1.05e-03	10	92	2	PF02815
Domain	MIR	RYR2 ITPR3	1.05e-03	10	92	2	SM00472
Domain	Flavoprotein-like_dom	TYW1B TYW1	1.05e-03	10	92	2	IPR029039
Domain	MIR_motif	RYR2 ITPR3	1.05e-03	10	92	2	IPR016093
Domain	Na_trans_assoc	SCN1A SCN5A	1.05e-03	10	92	2	IPR010526
Domain	Na_trans_assoc	SCN1A SCN5A	1.05e-03	10	92	2	PF06512
Domain	-	TYW1B TYW1	1.05e-03	10	92	2	3.40.50.360
Domain	-	COL11A1 SVEP1 CELSR1 LMAN2L	1.25e-03	95	92	4	2.60.120.200
Domain	Filamin	TRIM2 MYCBP2	1.28e-03	11	92	2	PF00630
Domain	Integrin_alpha	ITGAD ITGAE	1.28e-03	11	92	2	PF00357
Domain	Fib_collagen_C	COL2A1 COL11A1	1.28e-03	11	92	2	IPR000885
Domain	COLFI	COL2A1 COL11A1	1.28e-03	11	92	2	PF01410
Domain	FILAMIN_REPEAT	TRIM2 MYCBP2	1.28e-03	11	92	2	PS50194
Domain	NC1_FIB	COL2A1 COL11A1	1.28e-03	11	92	2	PS51461
Domain	Filamin/ABP280_rpt	TRIM2 MYCBP2	1.28e-03	11	92	2	IPR001298
Domain	Fib_collagen_C	COL2A1 COL11A1	1.28e-03	11	92	2	PD002078
Domain	Filamin/ABP280_repeat-like	TRIM2 MYCBP2	1.28e-03	11	92	2	IPR017868
Domain	COLFI	COL2A1 COL11A1	1.28e-03	11	92	2	SM00038
Domain	VWF_A	MATN1 ITGAD ITGAE SVEP1	1.45e-03	99	92	4	IPR002035
Domain	NHL	TRIM2 TENM3	1.81e-03	13	92	2	PS51125
Domain	-	MYL3 MYL6 FKBP9 AIF1L RYR2 PPP2R3A	1.84e-03	261	92	6	1.10.238.10
Domain	EGF-like_CS	MATN1 CRELD2 SVEP1 CELSR1 TENM3 EPHA2	1.84e-03	261	92	6	IPR013032
Domain	EGF_2	MATN1 CRELD2 SVEP1 CELSR1 TENM3 EPHA2	1.99e-03	265	92	6	PS01186
Domain	MORN	MORN4 RSPH10B	2.10e-03	14	92	2	SM00698
Domain	MORN	MORN4 RSPH10B	2.42e-03	15	92	2	IPR003409
Domain	MORN	MORN4 RSPH10B	2.42e-03	15	92	2	PF02493
Domain	Ion_trans_dom	RYR2 ITPR3 SCN1A SCN5A	2.43e-03	114	92	4	IPR005821
Domain	Ion_trans	RYR2 ITPR3 SCN1A SCN5A	2.43e-03	114	92	4	PF00520
Domain	Integrin_alpha_C_CS	ITGAD ITGAE	2.75e-03	16	92	2	IPR018184
Domain	EGF_CA	MATN1 CRELD2 SVEP1 CELSR1	3.11e-03	122	92	4	SM00179
Domain	EGF-like_Ca-bd_dom	MATN1 CRELD2 SVEP1 CELSR1	3.30e-03	124	92	4	IPR001881
Domain	Integrin_alpha-2	ITGAD ITGAE	3.49e-03	18	92	2	IPR013649
Domain	Integrin_alpha2	ITGAD ITGAE	3.49e-03	18	92	2	PF08441
Domain	Integrin_alpha	ITGAD ITGAE	3.49e-03	18	92	2	IPR000413
Domain	INTEGRIN_ALPHA	ITGAD ITGAE	3.49e-03	18	92	2	PS00242
Domain	Int_alpha_beta-p	ITGAD ITGAE	3.89e-03	19	92	2	IPR013519
Domain	Cyclophilin-type_PPIase_CS	PPIB NKTR	3.89e-03	19	92	2	IPR020892
Domain	Int_alpha	ITGAD ITGAE	3.89e-03	19	92	2	SM00191
Domain	RCC1	MYCBP2 RCC2	4.30e-03	20	92	2	PF00415
Domain	ConA-like_dom	COL11A1 SVEP1 RYR2 CELSR1 LMAN2L	4.56e-03	219	92	5	IPR013320
Domain	RCC1_1	MYCBP2 RCC2	4.74e-03	21	92	2	PS00625
Domain	RCC1_2	MYCBP2 RCC2	4.74e-03	21	92	2	PS00626
Domain	Cyclophilin-type_PPIase	PPIB NKTR	4.74e-03	21	92	2	IPR024936
Domain	RCC1_3	MYCBP2 RCC2	4.74e-03	21	92	2	PS50012
Pathway	REACTOME_MUSCLE_CONTRACTION	MYL3 MYL6 KCNK13 RYR2 ITPR3 SCN1A SCN5A ATP2B2	5.68e-06	203	68	8	M5485
Pathway	REACTOME_CARDIAC_CONDUCTION	KCNK13 RYR2 ITPR3 SCN1A SCN5A ATP2B2	3.75e-05	130	68	6	M27454
Pathway	PID_SYNDECAN_1_PATHWAY	COL2A1 COL11A1 HPSE PPIB	6.94e-05	46	68	4	M198
Pathway	REACTOME_MUSCLE_CONTRACTION	MYL3 MYL6 KCNK13 RYR2 ITPR3 ATP2B2	1.41e-04	165	68	6	MM15026
Pathway	REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE	LIN7C LIN7A LIN7B	1.77e-04	23	68	3	MM14852
Pathway	REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE	LIN7C LIN7A LIN7B	1.77e-04	23	68	3	M12627
Pathway	WP_FOCAL_ADHESION	COL2A1 COL11A1 MYL6 ITGAD ITGAE MYLK2	2.78e-04	187	68	6	MM15913
Pathway	REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS	SPTB SCN1A SCN5A	4.38e-04	31	68	3	M877
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	COL2A1 COL11A1 MATN1 EMILIN2 ITGAD ITGAE PPIB	5.89e-04	300	68	7	M610
Pubmed	Renal defects associated with improper polarization of the CRB and DLG polarity complexes in MALS-3 knockout mice.	LIN7C LIN7A LIN7B	9.21e-08	4	100	3	17923534
Pubmed	Association study of brain-derived neurotrophic factor (BDNF) and LIN-7 homolog (LIN-7) genes with adult attention-deficit/hyperactivity disorder.	LIN7C LIN7A LIN7B	9.21e-08	4	100	3	18286632
Pubmed	MALS is a binding partner of IRSp53 at cell-cell contacts.	LIN7C LIN7A LIN7B	9.21e-08	4	100	3	14596909
Pubmed	Characterization of MALS/Velis-1, -2, and -3: a family of mammalian LIN-7 homologs enriched at brain synapses in association with the postsynaptic density-95/NMDA receptor postsynaptic complex.	LIN7C LIN7A LIN7B	2.30e-07	5	100	3	10341223
Pubmed	The stardust family protein MPP7 forms a tripartite complex with LIN7 and DLG1 that regulates the stability and localization of DLG1 to cell junctions.	LIN7C LIN7A LIN7B	2.30e-07	5	100	3	17237226
Pubmed	Contrasting localizations of MALS/LIN-7 PDZ proteins in brain and molecular compensation in knockout mice.	LIN7C LIN7A LIN7B	2.30e-07	5	100	3	11104771
Pubmed	A unified assembly mode revealed by the structures of tetrameric L27 domain complexes formed by mLin-2/mLin-7 and Patj/Pals1 scaffold proteins.	LIN7C LIN7A LIN7B	4.58e-07	6	100	3	15863617
Pubmed	A tripartite protein complex with the potential to couple synaptic vesicle exocytosis to cell adhesion in brain.	LIN7C LIN7A LIN7B	8.01e-07	7	100	3	9753324
Pubmed	A multiprotein trafficking complex composed of SAP97, CASK, Veli, and Mint1 is associated with inward rectifier Kir2 potassium channels.	LIN7C LIN7A LIN7B	2.73e-06	10	100	3	14960569
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	SRRM1 MYL3 MYL6 DSG1 MARS1 COPB2 PPIB RCC2 ITPR3 CSDE1 CACTIN SUPT16H CTTN	3.41e-06	949	100	13	36574265
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	MYL6 UBE4B FNTB MARS1 COPB2 FKBP9 IDE WNK1 PPIB RCC2 CSDE1 ASB6 DNAAF10 SUPT16H CTTN HECTD1	3.96e-06	1455	100	16	22863883
Pubmed	Kinesin superfamily motor protein KIF17 and mLin-10 in NMDA receptor-containing vesicle transport.	LIN7C LIN7A LIN7B	4.98e-06	12	100	3	10846156
Pubmed	Incidence of mandibular distraction osteogenesis in Stickler Syndrome: Variation due to COL2A1 and COL11A1.	COL2A1 COL11A1	8.18e-06	2	100	2	34004386
Pubmed	Loss of Nav1.5 expression and function in murine atria containing the RyR2-P2328S gain-of-function mutation.	RYR2 SCN5A	8.18e-06	2	100	2	23723061
Pubmed	Mutation Spectrum and De Novo Mutation Analysis in Stickler Syndrome Patients with High Myopia or Retinal Detachment.	COL2A1 COL11A1	8.18e-06	2	100	2	32756486
Pubmed	Stickler syndrome and the vitreous phenotype: mutations in COL2A1 and COL11A1.	COL2A1 COL11A1	8.18e-06	2	100	2	20513134
Pubmed	A truncated alternative spliced isoform of human desmoglein 1 contains a specific T cell epitope binding to the pemphigus foliaceus-associated HLA class II DRbeta1*0102 molecule.	DSG1 HLA-DRB1	8.18e-06	2	100	2	17056584
Pubmed	Genetic Characteristics and Phenotype of Korean Patients with Stickler Syndrome: A Korean Multicenter Analysis Report No. 1.	COL2A1 COL11A1	8.18e-06	2	100	2	34680973
Pubmed	Taf1 knockout is lethal in embryonic male mice and heterozygous females show weight and movement disorders.	TAF1 TAF1L	8.18e-06	2	100	2	38804708
Pubmed	Wide long lasting perinuclear Ca2+ release events generated by an interaction between ryanodine and IP3 receptors in canine Purkinje cells.	RYR2 ITPR3	8.18e-06	2	100	2	18586264
Pubmed	Sustained expression of a neuron-specific isoform of the Taf1 gene in development stages and aging in mice.	TAF1 TAF1L	8.18e-06	2	100	2	22842574
Pubmed	Expanding the phenotype spectrum associated with pathogenic variants in the COL2A1 and COL11A1 genes.	COL2A1 COL11A1	8.18e-06	2	100	2	32427345
Pubmed	Frameshift Mutations in the Mononucleotide Repeats of TAF1 and TAF1L Genes in Gastric and Colorectal Cancers with Regional Heterogeneity.	TAF1 TAF1L	8.18e-06	2	100	2	27571988
Pubmed	Striatal Cholinergic Dysregulation after Neonatal Decrease in X-Linked Dystonia Parkinsonism-Related TAF1 Isoforms.	TAF1 TAF1L	8.18e-06	2	100	2	34403156
Pubmed	Splicing mutations of 54-bp exons in the COL11A1 gene cause Marshall syndrome, but other mutations cause overlapping Marshall/Stickler phenotypes.	COL2A1 COL11A1	8.18e-06	2	100	2	10486316
Pubmed	Mutation survey and genotype-phenotype analysis of COL2A1 and COL11A1 genes in 16 Chinese patients with Stickler syndrome.	COL2A1 COL11A1	8.18e-06	2	100	2	27390512
Pubmed	Changes in type II procollagen isoform expression during chondrogenesis by disruption of an alternative 5' splice site within Col2a1 exon 2.	COL2A1 COL11A1	8.18e-06	2	100	2	24735995
Pubmed	rse, a novel receptor-type tyrosine kinase with homology to Axl/Ufo, is expressed at high levels in the brain.	TYRO3 EPHA2	8.18e-06	2	100	2	7511603
Pubmed	Purkinje Cells as Sources of Arrhythmias in Long QT Syndrome Type 3.	RYR2 SCN5A	8.18e-06	2	100	2	26289036
Pubmed	Hearing Outcomes in Stickler Syndrome: Variation Due to COL2A1 and COL11A1.	COL2A1 COL11A1	8.18e-06	2	100	2	34238052
Pubmed	Splicing analysis of unclassified variants in COL2A1 and COL11A1 identifies deep intronic pathogenic mutations.	COL2A1 COL11A1	8.18e-06	2	100	2	22189268
Pubmed	Discovery of a gene family critical to wyosine base formation in a subset of phenylalanine-specific transfer RNAs.	TYW1B TYW1	8.18e-06	2	100	2	16162496
Pubmed	TYRO3 and EPHA2 Expression Are Dysregulated in Breast Cancer.	TYRO3 EPHA2	8.18e-06	2	100	2	39327735
Pubmed	Molecular cloning of a novel receptor tyrosine kinase, tif, highly expressed in human ovary and testis.	TYRO3 EPHA2	8.18e-06	2	100	2	8108143
Pubmed	Genetic analysis in post-mortem samples with micro-ischemic alterations.	RYR2 SCN5A	8.18e-06	2	100	2	28086167
Pubmed	Regulatory mechanisms and pathophysiological significance of IP3 receptors and ryanodine receptors in drug dependence.	RYR2 ITPR3	8.18e-06	2	100	2	24285081
Pubmed	Mutation in the neuronal voltage-gated sodium channel SCN1A in familial hemiplegic migraine.	SCN1A SCN5A	8.18e-06	2	100	2	16054936
Pubmed	Phenotypic characterization of patients with early-onset high myopia due to mutations in COL2A1 or COL11A1: Why not Stickler syndrome?	COL2A1 COL11A1	8.18e-06	2	100	2	30181686
Pubmed	Comparative structural analysis of human Nav1.1 and Nav1.5 reveals mutational hotspots for sodium channelopathies.	SCN1A SCN5A	8.18e-06	2	100	2	33712547
Pubmed	TAFII250, Egr-1, and D-type cyclin expression in mice and neonatal rat cardiomyocytes treated with doxorubicin.	TAF1 TAF1L	8.18e-06	2	100	2	10070062
Pubmed	Mass spectrometric analysis identifies a cortactin-RCC2/TD60 interaction in mitotic cells.	RCC2 CTTN	8.18e-06	2	100	2	22282019
Pubmed	Synthesis, maturation, and trafficking of human Na+-dicarboxylate cotransporter NaDC1 requires the chaperone activity of cyclophilin B.	SLC13A2 PPIB	8.18e-06	2	100	2	21257749
Pubmed	Epistasis between DSG1 and HLA class II genes in pemphigus foliaceus.	DSG1 HLA-DRB1	8.18e-06	2	100	2	12058255
Pubmed	Ligand targeting of EphA2 enhances keratinocyte adhesion and differentiation via desmoglein 1.	DSG1 EPHA2	8.18e-06	2	100	2	20861311
Pubmed	Collagen II is essential for the removal of the notochord and the formation of intervertebral discs.	COL2A1 COL11A1 MATN1	1.02e-05	15	100	3	9832566
Pubmed	Perlecan maintains the integrity of cartilage and some basement membranes.	COL2A1 COL11A1 MATN1	1.02e-05	15	100	3	10579729
Pubmed	Brain-specific angiogenesis inhibitor-1 signaling, regulation, and enrichment in the postsynaptic density.	LIN7A MAGI2 PDZD2	1.02e-05	15	100	3	23782696
Pubmed	Intact lipid rafts regulate HIV-1 Tat protein-induced activation of the Rho signaling and upregulation of P-glycoprotein in brain endothelial cells.	MYL3 MYL6 ABCB4	1.26e-05	16	100	3	19794400
Pubmed	MALS-3 regulates polarity and early neurogenesis in the developing cerebral cortex.	LIN7C LIN7A LIN7B	1.52e-05	17	100	3	18403412
Pubmed	Protein trafficking and anchoring complexes revealed by proteomic analysis of inward rectifier potassium channel (Kir2.x)-associated proteins.	LIN7C LIN7A LIN7B	2.16e-05	19	100	3	15024025
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	MORN4 MYL6 DSG1 MYCBP2 CYTH2 COPB2 RYR2 LIN7A CSDE1 MAGI2 SCN1A CTTN FAM177A1	2.37e-05	1139	100	13	36417873
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	SRRM1 LIN7C FNTB COPB2 DPYSL5 IDE RCC2 LIN7A ITPR3 EPHA2 CTTN HECTD1	2.38e-05	974	100	12	28675297
Pubmed	Developmental expression analysis of murine autotaxin (ATX).	COL2A1 ENPP2	2.45e-05	3	100	2	10473125
Pubmed	Col11a1 and Col11a2 mRNA expression in the developing mouse cochlea: implications for the correlation of hearing loss phenotype with mutant type XI collagen genotype.	COL2A1 COL11A1	2.45e-05	3	100	2	15141750
Pubmed	Enhancement of cell adhesion and spreading by a cartilage-specific noncollagenous protein, cartilage matrix protein (CMP/Matrilin-1), via integrin alpha1beta1.	COL2A1 MATN1	2.45e-05	3	100	2	10196235
Pubmed	Protein expression profiles in murine ventricles modeling catecholaminergic polymorphic ventricular tachycardia: effects of genotype and sex.	RYR2 SCN5A	2.45e-05	3	100	2	32713021
Pubmed	Histochemical, immunofluorescence, and ultrastructural differences in fetal cartilage among three genetically distinct chondrodystrophic mice.	COL2A1 COL11A1	2.45e-05	3	100	2	3070812
Pubmed	Regulated expression of TAF1 in 1-cell mouse embryos.	TAF1 TAF1L	2.45e-05	3	100	2	16822332
Pubmed	Glycerophosphodiesterase GDE4 as a novel lysophospholipase D: a possible involvement in bioactive N-acylethanolamine biosynthesis.	GDPD1 ENPP2	2.45e-05	3	100	2	25596343
Pubmed	TAFII55 binding to TAFII250 inhibits its acetyltransferase activity.	TAF1 TAF1L	2.45e-05	3	100	2	11592977
Pubmed	LIN7 regulates the filopodium- and neurite-promoting activity of IRSp53.	LIN7C LIN7A	2.45e-05	3	100	2	22767515
Pubmed	Functional substitution for TAF(II)250 by a retroposed homolog that is expressed in human spermatogenesis.	TAF1 TAF1L	2.45e-05	3	100	2	12217962
Pubmed	TAF7: a possible transcription initiation check-point regulator.	TAF1 TAF1L	2.45e-05	3	100	2	16407123
Pubmed	CASK deletion in intestinal epithelia causes mislocalization of LIN7C and the DLG1/Scrib polarity complex without affecting cell polarity.	LIN7C LIN7A LIN7B	2.54e-05	20	100	3	19726564
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	SRRM1 MYL6 LIN7C MYCBP2 FNTB MARS1 COPB2 AIF1L PPIB RCC2 DNAAF10 SUPT16H CTTN	2.59e-05	1149	100	13	35446349
Pubmed	Sequential genome-wide CRISPR-Cas9 screens identify genes regulating cell-surface expression of tetraspanins.	CYTH2 KCNK13 IDE SMCO2 PALB2 MYLK2 MAGI2 DNAAF10 AK5 ATP2B2 RSPH10B	2.81e-05	832	100	11	36724073
Pubmed	Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.	SRRM1 LIN7C DSG1 COPB2 OAS3 MUC5B IDE WNK1 PPIB RCC2 CSDE1 EPHA2 SUPT16H CTTN	3.70e-05	1367	100	14	32687490
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	COL2A1 SRRM1 COL11A1 MYL6 DSG1 RBM3 OAS3 PPIB VIRMA CSDE1 CACTIN EPHA2 SUPT16H NKTR	3.81e-05	1371	100	14	36244648
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	MYCBP2 FKBP9 CRELD2 OGFOD3 PPIB CSDE1 CELSR1 LMAN2L TENM3 TMEM106C EPHA2 TYW1 HECTD1	4.09e-05	1201	100	13	35696571
Pubmed	Genome wide association study (GWAS) of Chagas cardiomyopathy in Trypanosoma cruzi seropositive subjects.	SPTB EMILIN2 MAGI2 DNAAF10 MGAT4C	4.42e-05	134	100	5	24324551
Pubmed	Collagen XI chain misassembly in cartilage of the chondrodysplasia (cho) mouse.	COL2A1 COL11A1	4.89e-05	4	100	2	17683922
Pubmed	X-ray crystal structure of HLA-DR4 (DRA0101, DRB10401) complexed with a peptide from human collagen II.	COL2A1 HLA-DRB1	4.89e-05	4	100	2	9354468
Pubmed	Lineage tracing using matrilin-1 gene expression reveals that articular chondrocytes exist as the joint interzone forms.	COL2A1 MATN1	4.89e-05	4	100	2	17313942
Pubmed	The function and interrelationship between GDF5 and ERG-010 during chondrogenesis in vitro.	COL2A1 MATN1	4.89e-05	4	100	2	26542169
Pubmed	Mutations in collagen genes resulting in metaphyseal and epiphyseal dysplasias.	COL2A1 COL11A1	4.89e-05	4	100	2	8579897
Pubmed	Murine models of human genetic skeletal disorders.	COL2A1 COL11A1	4.89e-05	4	100	2	9205941
Pubmed	Ribonucleome analysis identified enzyme genes responsible for wybutosine synthesis.	TYW1B TYW1	4.89e-05	4	100	2	17150819
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	SRRM1 MYL6 DSG1 MARS1 RBM3 COPB2 WNK1 PPIB RCC2 CSDE1 DNAAF10 SUPT16H CTTN HECTD1	5.36e-05	1415	100	14	28515276
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	SRRM1 VIRMA RCC2 FER1L6 SUPT16H CTTN	6.12e-05	234	100	6	36243803
Pubmed	Chondromodulin I is dispensable during enchondral ossification and eye development.	COL2A1 COL11A1 MATN1	6.42e-05	27	100	3	12192060
Pubmed	SARS-CoV-2 uses Spike glycoprotein to control the host's anaerobic metabolism by inhibiting LDHB.	SRRM1 MARS1 COPB2 PPIB VIRMA RCC2 CSDE1 SUPT16H CTTN	6.58e-05	607	100	9	39147351
Pubmed	PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation.	SRRM1 DSG1 UBE4B PPIB SCN5A SUPT16H NKTR CTTN	7.30e-05	477	100	8	31300519
Pubmed	An orphan receptor tyrosine kinase family whose members serve as nonintegrin collagen receptors.	COL2A1 COL11A1	8.14e-05	5	100	2	9659900
Pubmed	Ro52 functionally interacts with IgG1 and regulates its quality control via the ERAD system.	UBE4B HLA-DRB1	8.14e-05	5	100	2	18022694
Pubmed	Identification of HAX-1 as a protein that binds bile salt export protein and regulates its abundance in the apical membrane of Madin-Darby canine kidney cells.	ABCB4 CTTN	8.14e-05	5	100	2	15159385
Pubmed	Chromosomal localization and genomic cloning of the mouse alpha-tropomyosin gene Tpm-1.	MYL3 SCN5A	8.14e-05	5	100	2	8406508
Pubmed	MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.	MYCBP2 CSDE1 TYRO3 MAGI2 TENM3 SUPT16H TAF1	8.14e-05	358	100	7	32460013
Pubmed	Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation.	SRRM1 MYL6 LIN7C MYCBP2 VIRMA DNAAF10 SUPT16H	8.57e-05	361	100	7	30344098
Pubmed	Neurotransmitter release regulated by a MALS-liprin-alpha presynaptic complex.	LIN7C LIN7A LIN7B	8.85e-05	30	100	3	16186258
Pubmed	Roles of I(f) and intracellular Ca2+ release in spontaneous activity of ventricular cardiomyocytes during murine embryonic development.	RYR2 ITPR3	1.22e-04	6	100	2	23463619
Pubmed	Expression patterns of cartilage collagens and Sox9 during mouse heart development.	COL2A1 COL11A1	1.22e-04	6	100	2	12883905
Pubmed	Essential Roles of Intracellular Calcium Release Channels in Muscle, Brain, Metabolism, and Aging.	RYR2 ITPR3	1.22e-04	6	100	2	25966694
Pubmed	Regulation of collagen fibril nucleation and initial fibril assembly involves coordinate interactions with collagens V and XI in developing tendon.	COL2A1 COL11A1	1.22e-04	6	100	2	21467034
Pubmed	Molecular cloning and characterization of Pals, proteins associated with mLin-7.	LIN7C LIN7A	1.22e-04	6	100	2	10753959
Pubmed	The role of collagen II and cartilage fibril-associated molecules in skeletal development.	COL2A1 MATN1	1.22e-04	6	100	2	11680679
Pubmed	The collagen family members as cell adhesion proteins.	COL2A1 COL11A1	1.22e-04	6	100	2	17876790
Pubmed	The role of sequence variations within the genes encoding collagen II, IX and XI in non-syndromic, early-onset osteoarthritis.	COL2A1 COL11A1	1.22e-04	6	100	2	15922184
Pubmed	Transforming growth factor-beta regulates basal transcriptional regulatory machinery to control cell proliferation and differentiation in cranial neural crest-derived osteoprogenitor cells.	TAF1 TAF1L	1.22e-04	6	100	2	19959467
Pubmed	Retarded skeletal development in transgenic mice with a type II collagen mutation.	COL2A1 COL11A1	1.22e-04	6	100	2	8952549
Pubmed	A calcium-induced calcium release mechanism supports luteinizing hormone-induced testosterone secretion in mouse Leydig cells.	RYR2 ITPR3	1.22e-04	6	100	2	20519450
Interaction	CACNA1D interactions	VIRMA RYR2 SCN1A SCN5A	4.98e-06	24	97	4	int:CACNA1D
Interaction	PXDC1 interactions	LIN7C LIN7A LIN7B	8.89e-06	9	97	3	int:PXDC1
Cytoband	8q24.1	ENPP2 FER1L6	9.79e-05	7	100	2	8q24.1
Cytoband	12q21	LIN7A MGAT4C	3.61e-04	13	100	2	12q21
GeneFamily	PDZ domain containing\|Crumbs complex	LIN7C LIN7A LIN7B	2.33e-06	9	56	3	1223
GeneFamily	PDZ domain containing	LIN7C LIN7A LIN7B MAGI2 FRMPD2B PDZD2	7.34e-06	152	56	6	1220
GeneFamily	EF-hand domain containing	MYL3 MYL6 FKBP9 AIF1L RYR2 PPP2R3A	5.78e-05	219	56	6	863
GeneFamily	Sodium voltage-gated channel alpha subunits	SCN1A SCN5A	3.35e-04	9	56	2	1203
GeneFamily	Myosin light chains\|EF-hand domain containing	MYL3 MYL6	8.37e-04	14	56	2	657
GeneFamily	CD molecules\|Integrin alpha subunits	ITGAD ITGAE	1.40e-03	18	56	2	1160
GeneFamily	Cyclophilin peptidylprolyl isomerases	PPIB NKTR	1.56e-03	19	56	2	909
GeneFamily	Collagens	COL2A1 COL11A1	8.94e-03	46	56	2	490
ToppCell	wk_15-18-Mesenchymal-Chondrocyte\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	COL2A1 COL11A1 ENPP2 MATN1 AIF1L TENM3 SCN1A	1.77e-07	181	100	7	8950844b3e65c7028d80da5787ae2ce509c3d52d
ToppCell	Substantia_nigra-Macroglia-OLIGODENDROCYTE-O1-Tfr\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	ENPP2 EMILIN2 KCNK13 FSIP2 FAM177A1	2.07e-06	92	100	5	0754a79efc4c0659d9a2acfe4185bcae1a3e7206
ToppCell	Substantia_nigra-Macroglia-OLIGODENDROCYTE-O1\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	ENPP2 EMILIN2 KCNK13 FSIP2 FAM177A1	2.07e-06	92	100	5	aee1fd2419dc1fc7039c0ac56f0ba23ed11d668f
ToppCell	wk_15-18-Mesenchymal-Chondrocyte-intermediate_chondrocyte\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	COL2A1 COL11A1 ENPP2 AIF1L TENM3 SCN1A	2.80e-06	175	100	6	a84965d28438a4228d841b357c2cd75cf4b59a63
ToppCell	COVID-19-Heart\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MYL3 SMYD1 SPTB RYR2 SCN5A PDZD2	4.49e-06	190	100	6	918ad5037881212008f9f69d5df5da91fd01422c
ToppCell	Globus_pallidus-Neuronal\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	MYCBP2 SPTB DPYSL5 RYR2 LIN7B ATP2B2	4.49e-06	190	100	6	416de85d8841dac883faa6f5339b2fb461a09e82
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_chondroblast_(18)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	COL2A1 COL11A1 MATN1 AIF1L TENM3 PDZD2	4.63e-06	191	100	6	f9a46956778a8773d6656340ecf5d218376d79c2
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_chondroblast_(18)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	COL2A1 COL11A1 ENPP2 TENM3 SCN1A MGAT4C	4.77e-06	192	100	6	d0649410cf5eacdb0c1dce70e37c7473ef5fddfa
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c5-CD16\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	HPSE KCNRG ITPR3 MGAT4C	1.78e-05	69	100	4	1592edde44c3927d6a2350eb00f92c10d3adf692
ToppCell	Posterior_cortex-Macroglia-OLIGODENDROCYTE-O2-Tfr-Oligodendrocyte.Tfr.Klk6_(Klk6)-\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	COL2A1 EMILIN2 SMCO2 FAM177A1	2.35e-05	74	100	4	88d6112e16d537bbbb73f206f3388b5a951e68b4
ToppCell	Posterior_cortex-Macroglia-OLIGODENDROCYTE-O2-Tfr-Oligodendrocyte.Tfr.Klk6_(Klk6)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	COL2A1 EMILIN2 SMCO2 FAM177A1	2.35e-05	74	100	4	b61bfa778b295a05db58b231d1fca7cb69aab8c3
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL11A1 MUC5B SVEP1 RYR2 LIN7A	3.06e-05	160	100	5	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL11A1 MUC5B SVEP1 RYR2 LIN7A	3.06e-05	160	100	5	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TRIM2 ARHGAP40 MUC5B CELSR1 EPHA2	3.16e-05	161	100	5	2d63b279d9a5132e1c09b03930bf9039036d24a2
ToppCell	Smart-seq2-tissue-resident_(Smart-seq2)-hematologic-erythrocytic-erythrocyte\|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	SMYD1 SPTB PALB2 CTTN ATP2B2	3.25e-05	162	100	5	25a11e4c6304324310b33a33331ebc812d045d4a
ToppCell	E17.5-Mesenchymal-mesenchymal_fibroblast-tracheal_fibroblast\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	COL2A1 COL11A1 MATN1 MAGI2 TENM3	3.98e-05	169	100	5	58e22f9119240664515fe91ca53812611a8f17d6
ToppCell	3'-GW_trimst-2-LargeIntestine-Epithelial-epithelial_progenitor_cell\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL2A1 TRIM2 MUC5B SLC13A2 EPHA2	4.21e-05	171	100	5	3ef44a5e3e8f81424f1e9aa302860b6688a549b8
ToppCell	3'-GW_trimst-2-LargeIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL2A1 TRIM2 MUC5B SLC13A2 EPHA2	4.21e-05	171	100	5	3a2fefcb62e9d47ae6b3a946c45d3f2dd32c576c
ToppCell	facs-Heart-Unknown-3m-Mesenchymal-atrial_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYL3 SMYD1 SPTB RYR2 SCN5A	4.32e-05	172	100	5	ee8ce9e8c9a6d3ee2be113f77743958005f4b3f0
ToppCell	facs-Heart-Unknown-3m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYL3 SMYD1 SPTB RYR2 SCN5A	4.32e-05	172	100	5	bd468a7ea6ec832dcf6a816a1e0c03fa0f176dad
ToppCell	facs-Large_Intestine-Distal-24m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYL3 SMYD1 SPTB SCN5A MN1	4.45e-05	173	100	5	f0eb48c1283bdde313bb75f6ffc0d2626922d24b
ToppCell	droplet-Lung-nan-21m-Lymphocytic-Plasma_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRELD2 MUC5B OGFOD3 LIN7B SCN5A	4.57e-05	174	100	5	3f4277763e312b46ebd4401ea4a2f5d4c850c768
ToppCell	droplet-Lung-nan-21m-Lymphocytic-plasma_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRELD2 MUC5B OGFOD3 LIN7B SCN5A	4.57e-05	174	100	5	fad66d1a8407574b6a835e0bdb824a53afa58650
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte-Chondrocyte_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL2A1 COL11A1 ENPP2 MATN1 TENM3	4.70e-05	175	100	5	a5db428b078938627e61b7e944c1e0c1d61ac2da
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL2A1 COL11A1 ENPP2 MATN1 TENM3	4.70e-05	175	100	5	8b498eea1ec1c1f27b171025c3d08adf3687bafc
ToppCell	nucseq-Epithelial-Epithelial_Airway-Secretory/RAS\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	TRIM2 ARHGAP40 MUC5B FER1L6 CELSR1	4.96e-05	177	100	5	779ba86f53650772755b52460be03f18bb204e55
ToppCell	nucseq-Epithelial-Epithelial_Airway-Secretory/RAS-Secretory\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	TRIM2 ARHGAP40 MUC5B FER1L6 CELSR1	4.96e-05	177	100	5	0f210cfb61b873c5fd77dc17eadf4d017306500e
ToppCell	wk_15-18-Mesenchymal-Chondrocyte-Resting_chondrocyte\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	COL2A1 COL11A1 MATN1 AIF1L TENM3	4.96e-05	177	100	5	b01d7a6a78169962123ddfb0bb588f51d138ad02
ToppCell	Substantia_nigra-Macroglia-OLIGODENDROCYTE-O1-Tfr-Oligodendrocyte.Tfr.Il33_(Il33)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	ENPP2 KCNK13 ITGAD FAM177A1	5.07e-05	90	100	4	091bbcceecb7b5c30b92e0c991bb117561b43b89
ToppCell	Substantia_nigra-Macroglia-OLIGODENDROCYTE-O1-Tfr-Oligodendrocyte.Tfr.Il33_(Il33)-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	ENPP2 KCNK13 ITGAD FAM177A1	5.07e-05	90	100	4	5046bb6a66ce138c5c1dc4060d1360d494a91a67
ToppCell	Adult-Epithelial-club_cell-D122\|Adult / Lineage, Cell type, age group and donor	TRIM2 ARHGAP40 TYRO3 MAGI2 CELSR1	5.09e-05	178	100	5	35a2e3ba98b6f857dbb79cf8ddb4846ddcda6c17
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TRIM2 MUC5B FER1L6 EPHA2 NKTR	5.23e-05	179	100	5	6e965e424eebef50f0202cff75f458be395cfca1
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	COL11A1 TRIM2 FKBP9 CTAG2 CTTN	5.37e-05	180	100	5	e4add4c94f892a2d93926e5c6dac6a738319d091
ToppCell	droplet-Fat-Scat-21m-Hematologic-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MORN4 DPYSL5 KCNRG AK5	5.52e-05	92	100	4	246aebf5f17d50f67a7b48f713ea5043cefefb24
ToppCell	PND01-03-samps-Mesenchymal-Myofibroblast\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	COL11A1 ENPP2 MYLK2 TENM3 MN1	5.66e-05	182	100	5	812dac35b9aa05be48258082e007f6c00e7b4dd8
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TRIM2 ARHGAP40 FER1L6 CELSR1 EPHA2	5.66e-05	182	100	5	215c303df42f13597b2c7a95cb157c6bc7aca9a1
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TRIM2 ARHGAP40 MUC5B FER1L6 CELSR1	5.66e-05	182	100	5	3f1a666fe27dd7529c114539ed5f6b8ca585c875
ToppCell	wk_08-11-Mesenchymal-Chondrocyte-Resting_chondrocyte\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	COL2A1 COL11A1 MATN1 TRAPPC8 TENM3	5.66e-05	182	100	5	00a148b1e499bf16325491536d187d4dd6b70c06
ToppCell	wk_20-22-Mesenchymal-Chondrocyte-intermediate_chondrocyte\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	COL2A1 COL11A1 PPP2R3A TENM3 MN1	5.80e-05	183	100	5	1464b5c4425e8776c4aeb4d2b560481d4bf13931
ToppCell	COVID-19-Heart-CM_1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MYL3 SMYD1 SPTB RYR2 SCN5A	5.96e-05	184	100	5	e737f0f14c49b07bbb04a165083ac32210bc5690
ToppCell	COVID-19-Heart-CM_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MYL3 SMYD1 SPTB RYR2 SCN5A	6.11e-05	185	100	5	549eeb521c3985bff396ea0f202db21822efa51f
ToppCell	PCW_07-8.5-Neuronal-Neuronal_SCP-neuro_proliferating_SCP1_(1)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	COL2A1 DPYSL5 AIF1L AK5 SCN1A	6.27e-05	186	100	5	3113c85d0ac5fc46532c19b1bb71f34b985e1276
ToppCell	facs-Heart-Unknown-3m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYL3 SMYD1 SPTB RYR2 SCN5A	6.43e-05	187	100	5	0ffb988e0da2c7205c3515eca8e9851739bff5c5
ToppCell	facs-Heart-Unknown\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYL3 SMYD1 SPTB RYR2 SCN5A	6.43e-05	187	100	5	362e56426a568423a81e8a30e3ecf99b76135843
ToppCell	facs-Heart-Unknown-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYL3 SMYD1 SPTB RYR2 SCN5A	6.43e-05	187	100	5	c004567767b89f3d89f5c7b28d952f3445957e1e
ToppCell	facs-Heart-Unknown-3m-Mesenchymal-ventricular_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYL3 SMYD1 SPTB RYR2 SCN5A	6.59e-05	188	100	5	4db566f3f708e66730aa9e16f4d73d91dc534177
ToppCell	facs-Heart-Unknown-3m-Mesenchymal-ventricular_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYL3 SMYD1 SPTB RYR2 SCN5A	6.59e-05	188	100	5	6704b92991ad8c0a910e9f36cd33d00bd26dcb8f
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|World / Chamber and Cluster_Paper	MYL3 SMYD1 RYR2 PPP2R3A PDZD2	6.76e-05	189	100	5	5e80c47f63980904c4c1ff02c201b67b456a0974
ToppCell	droplet-Fat-Scat-21m-Hematologic\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MORN4 DPYSL5 KCNRG AK5	6.79e-05	97	100	4	440d45ecfc9b66cb61d734118601e745892d51e3
ToppCell	droplet-Fat-Scat-21m-Hematologic-erythroblast\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MORN4 DPYSL5 KCNRG AK5	6.79e-05	97	100	4	6fff45d4c4bbd81a67e1ad12b131cfe6a5ab37e6
ToppCell	droplet-Mammary_Gland-nan-3m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ENPP2 FKBP9 EMILIN2 SVEP1 DNAAF10	6.93e-05	190	100	5	bd0d68dc1b6f388190a6ba8a83b011619abe2bdd
ToppCell	droplet-Mammary_Gland-nan-3m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ENPP2 FKBP9 EMILIN2 SVEP1 DNAAF10	6.93e-05	190	100	5	e275de94468872e70cf305b3b450823d4c9c5e3f
ToppCell	droplet-Mammary_Gland-nan-3m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ENPP2 FKBP9 EMILIN2 SVEP1 DNAAF10	6.93e-05	190	100	5	ee2f4a55d2fd18b83e55399b5b5697a15a2d2e70
ToppCell	facs-Heart-LV-24m-Mesenchymal-ventricular_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYL3 SMYD1 SPTB RYR2 SCN5A	7.11e-05	191	100	5	543da1197c7e62f2c9cbd4a51414bbaaa6d1a92f
ToppCell	facs-Heart-LV-24m-Mesenchymal-ventricular_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYL3 SMYD1 SPTB RYR2 SCN5A	7.11e-05	191	100	5	9d7d680da3979e256191b534ebd14c5383e0cf93
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_chondroblast_(18)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	COL2A1 COL11A1 MATN1 AIF1L TENM3	7.11e-05	191	100	5	273c4a757292a9301de0eaeacdec91c9866be229
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-Z\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TRIM2 ENPP2 DPYSL5 AIF1L AK5	7.28e-05	192	100	5	8dc3016601148243196e925641c9507e9d58c9e0
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TRIM2 ENPP2 DPYSL5 PPP2R3A AK5	7.65e-05	194	100	5	cb0422e7607dbd77204428b7e2c70dfe14a6ca11
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_secretory\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TRIM2 ARHGAP40 MUC5B FER1L6 CELSR1	7.83e-05	195	100	5	e7230a849ea31e6eef9bc6f5468938499450582d
ToppCell	facs-Bladder-nan-3m\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL11A1 MYL6 COPB2 FKBP9 CSDE1	8.03e-05	196	100	5	44f5b1b474399c9316729155f2ea95a82ca66e30
ToppCell	facs-Bladder-nan-3m-Epithelial\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL11A1 MYL6 COPB2 FKBP9 CSDE1	8.03e-05	196	100	5	c0e90d964baa2eb4fbd18a52379ccec5d3bf59a8
ToppCell	COVID-19-Heart-Mito_CM\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MYL3 SMYD1 SPTB RYR2 MYLK2	8.22e-05	197	100	5	44e49943d62bfe622b40ad0460093d31540544df
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FNTB ENPP2 AIF1L TYRO3 AK5	8.22e-05	197	100	5	82b8e22317cad6d3786bd70d91107007c0ccd7cd
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TRIM2 ENPP2 AIF1L TYRO3 AK5	8.42e-05	198	100	5	bdabdb11217ea16e5863aa6bfb0f04d48b17f81e
ToppCell	5'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Glia_2_(ELN+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL2A1 COL11A1 AIF1L TENM3 SCN5A	8.42e-05	198	100	5	52ddc1f1ed4ac4c3bac794c90b8feb03e3c221c4
ToppCell	saliva-Severe-critical_progression_d28-40-Epithelial-Epithelial,_Airway-squamous_epithelial_cell-Epi-Squamous\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TRIM2 AIF1L EPHA2 CTTN HECTD1	8.62e-05	199	100	5	a8f4bd0e65f36b29535864fae4347369d5c864d2
ToppCell	18-Airway-Mesenchymal-Cartilage\|Airway / Age, Tissue, Lineage and Cell class	COL2A1 COL11A1 MATN1 AIF1L TENM3	8.62e-05	199	100	5	f5d0aa4170367c080d3c2f01d9af3529762917fa
ToppCell	saliva-Severe-critical_progression_d28-40-Epithelial-Epithelial,_Airway-squamous_epithelial_cell\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TRIM2 AIF1L EPHA2 CTTN HECTD1	8.62e-05	199	100	5	eacea42e973f073b410f54c0a1b3a7f2dc2b5a29
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating-Cycling_Progenitors\|1_mon / Sample Type, Dataset, Time_group, and Cell type.	COL2A1 WNK1 RCC2 CELSR1 MN1	8.62e-05	199	100	5	358c4b3037f59378db8916a2fbe9ed4830cf1449
ToppCell	Bronchial-10x5prime-Stromal-Pericyte-Muscle_pericyte_pulmonary\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	MYL3 SPTB RYR2 LIN7A PDZD2	8.83e-05	200	100	5	12326cc6f0af24bacba9493dc79e7c7347db2f41
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TRIM2 ENPP2 AIF1L TYRO3 AK5	8.83e-05	200	100	5	3ce8a2db8c25e1169a0a544f644a63104749c5ee
ToppCell	wk_08-11-Epithelial\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	COL2A1 COL11A1 AIF1L ITPR3 CELSR1	8.83e-05	200	100	5	445fc7995ffc440c6256a6aab0bbf33fb0fea028
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TRIM2 ENPP2 AIF1L TYRO3 AK5	8.83e-05	200	100	5	0bfd41c12887479ceb62c3db0a3c3ba5007eb62b
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TRIM2 ENPP2 AIF1L TYRO3 AK5	8.83e-05	200	100	5	159377d904394d91e09913131e9a93e08189955a
ToppCell	Bronchial-10x5prime-Stromal-Pericyte\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	MYL3 SPTB RYR2 LIN7A PDZD2	8.83e-05	200	100	5	362706445edb33b313684efe50b1f44f5f816e67
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TRIM2 ENPP2 AIF1L TYRO3 AK5	8.83e-05	200	100	5	d30316836494f33ca46d4e415fd2ed179e9cb5ee
ToppCell	COVID-19-COVID-19_Mild\|COVID-19 / Disease, condition lineage and cell class	SRRM1 RBM3 HLA-DRB1 OAS3 NKTR	8.83e-05	200	100	5	62c25042086f1afd1102e0720e933c2e476468fd
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Neuronal-Intermediate\|2m / Sample Type, Dataset, Time_group, and Cell type.	TRIM2 DPYSL5 PPP2R3A HECTD1 MGAT4C	8.83e-05	200	100	5	2a635694844ddabcd98462c5636a6f41a3f08a46
ToppCell	Substantia_nigra-Macroglia-OLIGODENDROCYTE\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	ENPP2 EMILIN2 KCNK13 FAM177A1	1.15e-04	111	100	4	4a22732094a9781867d501d9c05ba652c2f25048
ToppCell	Thalamus-Macroglia-OLIGODENDROCYTE-O1-Trf\|Thalamus / BrainAtlas - Mouse McCarroll V32	ENPP2 EMILIN2 KCNK13 ITGAD	1.19e-04	112	100	4	cb351e57c99aaaf9ae6c7ff7e8ce5375552b1639
ToppCell	Thalamus-Macroglia-OLIGODENDROCYTE-O1-Trf-Oligodendrocyte.Trf.Il33_(Il33)\|Thalamus / BrainAtlas - Mouse McCarroll V32	ENPP2 EMILIN2 KCNK13 ITGAD	1.19e-04	112	100	4	999b5eeed4305e1a1385aadbaf017b64f21c1ee0
ToppCell	Thalamus-Macroglia-OLIGODENDROCYTE-O1-Trf-Oligodendrocyte.Trf.Il33_(Il33)-\|Thalamus / BrainAtlas - Mouse McCarroll V32	ENPP2 EMILIN2 KCNK13 ITGAD	1.19e-04	112	100	4	004cd69b66c3b26b9a61f03279b48230da351574
ToppCell	Thalamus-Macroglia-OLIGODENDROCYTE-O1\|Thalamus / BrainAtlas - Mouse McCarroll V32	ENPP2 EMILIN2 KCNK13 ITGAD	1.19e-04	112	100	4	502e3f356f6e1c959bff0a39c98f33f863ce8265
ToppCell	Globus_pallidus-Macroglia-OLIGODENDROCYTE-O1\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	ENPP2 EMILIN2 KCNK13 ITGAD	1.45e-04	118	100	4	d0dd5c882cd9e0a5eb0cb08e47877292126bd4ae
ToppCell	Globus_pallidus-Macroglia-OLIGODENDROCYTE-O1-Trf\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	ENPP2 EMILIN2 KCNK13 ITGAD	1.45e-04	118	100	4	4283699cb3ca7a112faa07727dfdc0b0a67fb779
ToppCell	Globus_pallidus-Macroglia-OLIGODENDROCYTE-O2\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	ENPP2 EMILIN2 KCNK13 ITGAD	1.65e-04	122	100	4	d4152c45dfbb979ddf8380b4896db753a79cad9e
ToppCell	Globus_pallidus-Macroglia-OLIGODENDROCYTE-O2-Trf\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	ENPP2 EMILIN2 KCNK13 ITGAD	1.65e-04	122	100	4	40f983623c990203df4ba997e296231489d51012
ToppCell	Posterior_cortex-Macroglia-OLIGODENDROCYTE\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	COL2A1 EMILIN2 KCNK13 ITGAD	1.76e-04	124	100	4	9f169fa17be1842a6bd83778ff30465a740edd5f
ToppCell	Thalamus-Macroglia-OLIGODENDROCYTE\|Thalamus / BrainAtlas - Mouse McCarroll V32	ENPP2 EMILIN2 KCNK13 WNK1	2.04e-04	129	100	4	b3cb0c10659d1216b8f7de3aa1f9aac101cb65dd
ToppCell	Globus_pallidus-Macroglia-OLIGODENDROCYTE\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	ENPP2 EMILIN2 KCNK13 ITGAD	2.04e-04	129	100	4	98a5f24de72d2ae6a57787226b2e523ddd13b2c5
ToppCell	PBMC-Mild-cDC_2\|Mild / Compartment, Disease Groups and Clusters	SVEP1 CTAG2 SCN1A PDZD2	2.43e-04	135	100	4	cb9d834f8301cf53f20e09c3f4cb6a148690196a
ToppCell	Hippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Nnat-Inhibitory_Gad1Gad2_Htr3a.Nnat_(Interneuron,__(candidate_CGE-derived_1))-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	MYL3 ITGAE PKDREJ	2.71e-04	56	100	3	45241df25dfb0374e387391f7f6ea9d8d2564356
ToppCell	Hippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Nnat-Inhibitory_Gad1Gad2_Htr3a.Nnat_(Interneuron,__(candidate_CGE-derived_1))\|Hippocampus / BrainAtlas - Mouse McCarroll V32	MYL3 ITGAE PKDREJ	2.71e-04	56	100	3	8e988e3b2c034f0418d90f2be35c42bd181b044f
ToppCell	Hippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Nnat\|Hippocampus / BrainAtlas - Mouse McCarroll V32	MYL3 ITGAE PKDREJ	2.71e-04	56	100	3	7fb4d1ee114f5ee481775bb5b6fee424147642db
ToppCell	facs-Lung-EPCAM-3m-Hematologic-leukocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL2A1 CLYBL CCDC180 MGAT4C	2.79e-04	140	100	4	731b46e4b815a45af1d0ce7ab4d0d0324ac8798f
ToppCell	facs-Lung-EPCAM-3m-Hematologic-Proliferating_Immune\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL2A1 CLYBL CCDC180 MGAT4C	2.79e-04	140	100	4	b30fc389583406ee6cb55112d0f7250d1b74c88a
ToppCell	facs-Lung-EPCAM-3m-Hematologic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL2A1 CLYBL CCDC180 MGAT4C	2.79e-04	140	100	4	35ecd887bb7827603ef673912ba820208a6368d2
ToppCell	IIH-CD8-proli_CD4\|IIH / Condition, Cell_class and T cell subcluster	MORN4 FKBP9 CTAG2 ASB6	3.28e-04	146	100	4	7fa6e35def3f7cffbee1e1c2f10b523bab678e14
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DPYSL5 LYSMD4 WNK1 SCN1A	3.72e-04	151	100	4	f41c6558a5874b6464c157027fdf202257c60e5b
ToppCell	pdx-Tumor_cells-T4\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	LIN7C ARHGAP40 RBM3 TLNRD1	3.82e-04	152	100	4	7ccc56b79c499dd48dab8e2d936edca5223b9356
Drug	AC1L1D8L	FKBP9 PPIB RYR2 ABCB4 DNAAF10 SCN5A	5.86e-07	71	97	6	CID000002241
Drug	Pinacidil [85371-64-8]; Up 200; 16.4uM; PC3; HT_HG-U133A	TRIM2 UBE4B ENPP2 RYR2 LIN7B CACTIN PAFAH2 ATP2B2	2.12e-06	198	97	8	6356_UP
Disease	Arrhythmogenic Right Ventricular Dysplasia	RYR2 SCN5A	2.94e-05	3	93	2	C0349788
Disease	gestational age, birth measurement	COL2A1 PPP2R3A TMEM106C	3.87e-05	21	93	3	EFO_0005112, EFO_0006921
Disease	Stickler syndrome	COL2A1 COL11A1	9.77e-05	5	93	2	cv:C0265253
Disease	Stickler syndrome, type 1	COL2A1 COL11A1	9.77e-05	5	93	2	C2020284
Disease	leptin measurement	ARHGAP40 HLA-DRB1 SPTB PDZD2	1.28e-04	81	93	4	EFO_0005000
Disease	Abnormal corpus callosum morphology	SUPT16H MN1	1.46e-04	6	93	2	C1842581
Disease	urinary albumin to creatinine ratio	MYL3 LIN7C HLA-DRB1 TYRO3 AK5	2.62e-04	179	93	5	EFO_0007778
Disease	oral microbiome measurement	ARHGAP40 SEC61A2 PDZD2	3.18e-04	42	93	3	EFO_0801229
Disease	idiopathic pulmonary fibrosis (is_implicated_in)	HLA-DRB1 MUC5B	3.49e-04	9	93	2	DOID:0050156 (is_implicated_in)
Disease	generalized epilepsy with febrile seizures plus 2 (implicated_via_orthology)	SCN1A SCN5A	4.35e-04	10	93	2	DOID:0111294 (implicated_via_orthology)
Disease	Dravet syndrome (implicated_via_orthology)	SCN1A SCN5A	4.35e-04	10	93	2	DOID:0080422 (implicated_via_orthology)
Disease	Cardiomyopathy	MYL3 MYLK2 SCN5A	4.44e-04	47	93	3	cv:C0878544
Disease	Tachycardia, Ventricular	RYR2 SCN5A	5.31e-04	11	93	2	C0042514
Disease	autosomal dominant nonsyndromic deafness (is_implicated_in)	COL11A1 ATP2B2	5.31e-04	11	93	2	DOID:0050564 (is_implicated_in)
Disease	Long QT Syndrome	RYR2 SCN5A	5.31e-04	11	93	2	C0023976
Disease	generalized epilepsy with febrile seizures plus (implicated_via_orthology)	SCN1A SCN5A	6.35e-04	12	93	2	DOID:0060170 (implicated_via_orthology)
Disease	Neurobehavioral Manifestations	UBE4B MAGI2	6.35e-04	12	93	2	C0525041
Disease	xanthine measurement	COL2A1 MATN1	7.49e-04	13	93	2	EFO_0010548
Disease	Hypertrophic Cardiomyopathy	MYL3 RYR2 MYLK2	7.84e-04	57	93	3	C0007194
Disease	lung carcinoma	COL2A1 HLA-DRB1 WNK1 SMCO2 CLYBL DNAAF10 AK5	8.41e-04	482	93	7	EFO_0001071
Disease	Global developmental delay	CSDE1 SUPT16H TAF1 MN1	8.45e-04	133	93	4	C0557874
Disease	osteoarthritis (implicated_via_orthology)	COL2A1 COL11A1	1.00e-03	15	93	2	DOID:8398 (implicated_via_orthology)
Disease	sleep duration	MYCBP2 SMYD1 MAGI2 PPP2R3A SCN1A PDZD2	1.02e-03	362	93	6	EFO_0005271
Disease	Spondyloepiphyseal Dysplasia	COL2A1 COL11A1	1.15e-03	16	93	2	C0038015
Disease	Spondyloepiphyseal Dysplasia Tarda, X-Linked	COL2A1 COL11A1	1.15e-03	16	93	2	C3541456
Disease	Schwartz-Jampel Syndrome, Type 1	COL2A1 COL11A1	1.15e-03	16	93	2	C4551479
Disease	Schwartz-Jampel Syndrome	COL2A1 COL11A1	1.15e-03	16	93	2	C0036391
Disease	Melnick-Needles Syndrome	COL2A1 COL11A1	1.15e-03	16	93	2	C0025237
Disease	Van Buchem disease	COL2A1 COL11A1	1.30e-03	17	93	2	C0432272
Disease	osteoarthritis, knee	COL2A1 DCDC1 ITPR3 MN1	1.60e-03	158	93	4	EFO_0004616
Disease	Osteochondrodysplasias	COL2A1 COL11A1	1.62e-03	19	93	2	C0029422
Disease	Dyschondroplasias	COL2A1 COL11A1	1.62e-03	19	93	2	C0013366
Disease	Multiple Epiphyseal Dysplasia	COL2A1 COL11A1	1.80e-03	20	93	2	C0026760
Disease	Moderate albuminuria	MYL3 HLA-DRB1 TYRO3	2.09e-03	80	93	3	HP_0012594
Disease	Primary familial hypertrophic cardiomyopathy	MYL3 MYLK2	2.18e-03	22	93	2	cv:C0949658
Disease	childhood aggressive behaviour measurement	ARHGAP40 SCN1A HECTD1	2.83e-03	89	93	3	EFO_0007663
Disease	Intellectual Disability	CSDE1 LMAN2L SCN1A SUPT16H TAF1 MN1	2.94e-03	447	93	6	C3714756

Protein segments in the cluster

Peptide	Gene	Start	Entry
MSGELSNRFQGGKAF	AIF1L	1	Q9BQI0
MKLFGFGSRRGQTAE	ANKRD20A8P	1	Q5CZ79
AQGDGCRGVAFNVMF	CTAG2	191	O75638
AEGAERDGKNNVAFM	COPB2	716	P35606
NSMGFGAERKIRQAG	CSDE1	781	O75534
GGDKEEAQMINRFCF	ASB6	226	Q9NWX5
VDMAGFIANNGTREG	CELSR1	1631	Q9NYQ6
FFFQMVGALQGKVEE	CCDC180	481	Q9P1Z9
FVGEKMFQIDSGRNA	ATP2B2	971	Q01814
QLGKGAFTFQGSMID	CLYBL	306	Q8N0X4
GFDEKAGGAQLGVMQ	COL2A1	186	P02458
GDMETFENIRAAGGK	MUC5B	1806	Q9HC84
GSVFAFGENKMGQLG	RCC2	221	Q9P258
MSSEEGKLFVGGLNF	RBM3	1	P98179
DRIGEQAEAMFGVGK	ITPR3	1026	Q14573
EGEVVNGMRNGFGMF	RSPH10B	156	P0C881
EGEVVNGMRNGFGMF	RSPH10B2	156	B2RC85
RLGEFKNGNFEMSGV	MGAT4C	431	Q9UBM8
RILFFKNGMGQDGHE	DCDC1	296	M0R2J8
GGRFMFMEEGANKTV	OGFOD3	256	Q6PK18
EGLGFNVMGGKEQNS	LIN7A	116	O14910
EGLGFNIMGGKEQNS	LIN7B	101	Q9HAP6
EGLGFNIMGGKEQNS	LIN7C	101	Q9NUP9
DLGFKMFAVGVGNAV	MATN1	401	P21941
KSNMGFGFTIIGGDE	MAGI2	431	Q86UL8
AQAGQLMGFFKGIDQ	LYSMD4	161	Q5XG99
FGESAGQMSNERGFE	FAM177A1	26	Q8N128
GQMSNERGFENVELG	FAM177A1	31	Q8N128
DQLNVFGEDTMGGFM	AK5	356	Q9Y6K8
GLRVFDKEGNGTVMG	MYL3	136	P08590
RGTMVQRGFGKFGEL	LRRIQ4	516	A6NIV6
MQDTGFNGEDIGKNT	FSIP2	306	Q5CZC0
AKFVTMGNFARGTGV	DNAAF10	31	Q96MX6
QGMFGQKGDEGARGF	COL11A1	1176	P12107
MQGVERFAIGVGEEF	ITGAE	331	P38570
FDKEGNGTVMGAEIR	MYL6	96	P60660
QGMLQVDFANRFVGG	PARG	731	Q86W56
GQAKMQGDTSRGIEF	MYLK2	216	Q9H1R3
QGAASQEGTMNRGDF	PDZD2	2656	O15018
GNMDKFVGLGVFVDT	LMAN2L	146	Q9H0V9
RGGAGENLENTMAAF	GDPD1	46	Q8N9F7
EFSGGVGAFAIMNNR	KCNK13	386	Q9HB14
DGRDQEFKMVGGQIF	KCNRG	36	Q8N5I3
EFKMVGGQIFVDRDG	KCNRG	41	Q8N5I3
MFRAAGGEKTGFVTA	PPP2R3A	766	Q06190
GNMGSNDKVGDFVAT	DSG1	396	Q02413
GIEVVMRQVFFGAGN	HPSE	376	Q9Y251
EGIGDKVGMFFQAVA	ABCB4	186	P21439
GFVQAVMGQFEGTDT	ITGAD	171	Q13349
VMTFAEDGGGKENQF	PALB2	991	Q86YC2
TLRNDKFIQAFGDGM	OR9A1P	291	Q8NGU1
FNVFVGKGQLITGMD	FKBP9	81	O95302
TGIQKQMEAFRDGFN	HECTD1	2456	Q9ULT8
NANGLGFSFVQMEKE	FRMPD2B	96	Q6IN97
QRVDFLGEAGIMGQF	EPHA2	656	P29317
ERFVAMNRGINEGGD	CYTH2	211	Q99418
GKMSEGINFSDNLGR	DDX12P	796	Q92771
FLNGQEEKAGMVSTG	HLA-DRB1	161	P01911
QMRFEGGFQGRCNKL	FNTB	281	P49356
FFRRAKEGMGQDEAQ	CACTIN	606	Q8WUQ7
GGQKEGARGFMFFII	IDE	361	P14735
ENAGMGRFTKVGEQE	EMILIN2	636	Q9BXX0
FNQGMVDTAKKNFGG	CRELD2	41	Q6UXH1
GFNFRKNFGIGEKMQ	SLC13A2	291	Q13183
SLGVAQVGRMNFGKD	RYR2	1206	Q92736
GFDNKVNSMQTVFVG	ENPP2	476	Q13822
RGVVGGKMDENRFVA	DPYSL5	361	Q9BPU6
GDVMEGQNLQGSFFR	PAFAH2	21	Q99487
EQGGKDSQFNMAEGF	OAS3	981	Q9Y6K5
AGQGERNFNETGLSM	MN1	16	Q10571
QEMNEGFGEGVSFRG	FER1L6	381	Q2WGJ9
SEQLVNFTGKAEMGG	TMEM106C	181	Q9BVX2
FVKEQAEVGGMGALF	SEC61A2	461	Q9H9S3
RVVKNFMIQGGDFSE	NKTR	66	P30414
QERQASGGGELFFMR	TAF1L	671	Q8IZX4
EQERQASGGGEMFFM	TAF1	651	P21675
VEVSGFRMTGVADNG	PKDREJ	926	Q9NTG1
MENVEVFTAEGKGRG	SMYD1	6	Q8NB12
VIKDFMIQGGDFTRG	PPIB	96	P23284
MGVNLFAGKFGRCIN	SCN5A	1351	Q14524
NQGGKGFGVENMATA	MYCBP2	721	O75592
KNLGFGMGIEFREGS	SUPT16H	346	Q9Y5B9
QNGFMKGENFEVGSK	SVEP1	2271	Q4LDE5
PGNKFQGMVFDFVTR	SCN1A	1526	P35498
RDVRDVFGVFNSGKM	ARHGAP40	121	Q5TG30
VFGVFNSGKMSSENG	ARHGAP40	126	Q5TG30
DSVRGFGGKFGVQMD	CTTN	116	Q14247
FGGKFGVQMDRVDQS	CTTN	121	Q14247
GFLNGKNAREFMGEL	SRRM1	91	Q8IYB3
GTFMEEFNSGKQFVR	UBE4B	1011	O95155
VQSQLNMGRFGEAGD	TLNRD1	96	Q9H1K6
ITRQDGMFDLVANGG	TENM3	896	Q9P273
GIRKFEDFLGSMENN	SPTB	1206	P11277
GFFQKLNVTEGAMQD	SMCO2	31	A6NFE2
RETMENSKNFGGGNI	TRAV40	66	A0A0B4J280
GRGGNMLVFVDVENT	TRAPPC8	1096	Q9Y2L5
EKSGLFRNMGRNEDG	TYW1	336	Q9NV66
GAGVFKMGRFQVSVA	WNK1	1851	Q9H4A3
QEGEFMLKFGSNGEG	TRIM2	651	Q9C040
GMEAFLRGRQNEKSG	VIRMA	516	Q69YN4
KSRGVGVFGDMAQDT	MARS1	596	P56192
QQFTLGRMLGKGEFG	TYRO3	516	Q06418
KSGLFRNMGRNEDGE	TYW1B	291	Q6NUM6
DNMTFEGEFKNGRVD	MORN4	81	Q8NDC4