Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	steroid 11-beta-monooxygenase activity	CYP11B1 CYP11B2	3.17e-05	2	113	2	GO:0004507
GeneOntologyMolecularFunction	corticosterone 18-monooxygenase activity	CYP11B1 CYP11B2	3.17e-05	2	113	2	GO:0047783
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	GAPVD1 FGD2 MYO9A OBSCN GIT2 ARHGEF39 RAPGEF3 TBCK BCAR3 PREX1 SEC23B	1.43e-04	507	113	11	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	GAPVD1 FGD2 MYO9A OBSCN GIT2 ARHGEF39 RAPGEF3 TBCK BCAR3 PREX1 SEC23B	1.43e-04	507	113	11	GO:0030695
GeneOntologyMolecularFunction	guanyl-nucleotide exchange factor activity	GAPVD1 FGD2 OBSCN ARHGEF39 RAPGEF3 BCAR3 PREX1	3.46e-04	231	113	7	GO:0005085
HumanPheno	Craniosynostosis	SETD1A ATR TCIRG1 STAT3 KPTN KANSL1 GLI3 PLK4 MED12	2.64e-05	190	44	9	HP:0001363
HumanPheno	Recurrent maladaptive behavior	SETD1A CIB2 ATR MYO9A CYP11B1 VPS13C CYP11B2 NBEA FBXL3 PALB2 STAT3 DHX30 RUSC2 KPTN PIEZO2 KANSL1 KCNJ1 USH1G HECW2 GLI3 SCN1A PRKCG TBC1D23 MED12	3.22e-05	1293	44	24	HP:5200241
HumanPheno	Reduced impulse control	SETD1A ATR MYO9A CYP11B1 VPS13C CYP11B2 NBEA FBXL3 PALB2 STAT3 RUSC2 KPTN PIEZO2 KANSL1 KCNJ1 HECW2 GLI3 SCN1A PRKCG TBC1D23 MED12	3.75e-05	1032	44	21	HP:5200045
HumanPheno	Prominent fingertip pads	DHX30 RUSC2 KPTN KANSL1 MED12	4.01e-05	46	44	5	HP:0001212
HumanPheno	Prominent digit pad	DHX30 RUSC2 KPTN KANSL1 MED12	4.95e-05	48	44	5	HP:0011298
MousePheno	abnormal urine progesterone level	CYP11B1 CYP11B2	4.10e-05	2	90	2	MP:0011545
MousePheno	abnormal urine deoxycorticosterone level	CYP11B1 CYP11B2	4.10e-05	2	90	2	MP:0011552
MousePheno	decreased urine corticosterone level	CYP11B1 CYP11B2	4.10e-05	2	90	2	MP:0011550
MousePheno	increased urine deoxycorticosterone level	CYP11B1 CYP11B2	4.10e-05	2	90	2	MP:0011553
MousePheno	increased urine progesterone level	CYP11B1 CYP11B2	4.10e-05	2	90	2	MP:0011546
MousePheno	increased brain size	CYP11B1 CYP11B2 NBEA KPTN GLI3	2.16e-04	85	90	5	MP:0005238
MousePheno	abnormal adrenal gland zona glomerulosa morphology	CYP11B1 CYP11B2	2.44e-04	4	90	2	MP:0008293
MousePheno	decreased urine aldosterone level	CYP11B1 CYP11B2	2.44e-04	4	90	2	MP:0011541
MousePheno	abnormal urine aldosterone level	CYP11B1 CYP11B2	2.44e-04	4	90	2	MP:0011539
MousePheno	abnormal urine corticosterone level	CYP11B1 CYP11B2	2.44e-04	4	90	2	MP:0011548
MousePheno	decreased urine hormone level	CYP11B1 CYP11B2	2.44e-04	4	90	2	MP:0014459
Domain	Cyt_P450_mitochondrial	CYP11B1 CYP11B2	3.50e-05	2	111	2	IPR002399
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DGKB URB2 VIRMA TENM2 STRIP2 DHX30 RUSC2 ZCCHC14 KANSL1 NAV1 MTCL1	9.85e-08	407	113	11	12693553
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	AMPD2 GAPVD1 MYO9A VIRMA HDAC7 STAT3 RUSC2 ZCCHC14 MDN1 NAV1 MAP3K10 PRKCG MTCL1 PLK4 SEC23B	1.36e-07	861	113	15	36931259
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SETD1A CDK12 OBSCN HDAC7 DHX30 ZCCHC14 VAC14 URB1 SYNE3 MDN1 KANSL1 SLC45A3 NAV1 NLRC5 PREX1 MED12	5.98e-07	1105	113	16	35748872
Pubmed	Common polymorphisms in the CYP11B1 and CYP11B2 genes: evidence for a digenic influence on hypertension.	CYP11B1 CYP11B2	1.05e-05	2	113	2	23150505
Pubmed	GRAde: a long-read sequencing approach to efficiently identifying the CYP11B1/CYP11B2 chimeric form in patients with glucocorticoid-remediable aldosteronism.	CYP11B1 CYP11B2	1.05e-05	2	113	2	35012455
Pubmed	Role of genetic variation in regulation of aldosterone biosynthesis.	CYP11B1 CYP11B2	1.05e-05	2	113	2	21164264
Pubmed	BCL-2 expression is mainly regulated by JAK/STAT3 pathway in human CD34+ hematopoietic cells.	BCL2 STAT3	1.05e-05	2	113	2	16841088
Pubmed	Signal transducer and activator of transcription 3 mediates apoptosis inhibition through reducing mitochondrial ROS and activating Bcl-2 in gemcitabine-resistant lung cancer A549 cells.	BCL2 STAT3	1.05e-05	2	113	2	33283880
Pubmed	The hamster adrenal cytochrome P450C11 has equipotent 11beta-hydroxylase and 19-hydroxylase activities, but no aldosterone synthase activity.	CYP11B1 CYP11B2	1.05e-05	2	113	2	8645611
Pubmed	Expression and localization of cytochrome P450(11beta,aldo) mRNA in the frog brain.	CYP11B1 CYP11B2	1.05e-05	2	113	2	12231255
Pubmed	A de novo unequal cross-over mutation between CYP11B1 and CYP11B2 genes causes familial hyperaldosteronism type I.	CYP11B1 CYP11B2	1.05e-05	2	113	2	20634641
Pubmed	Hereditary hypertension caused by chimaeric gene duplications and ectopic expression of aldosterone synthase.	CYP11B1 CYP11B2	1.05e-05	2	113	2	1303253
Pubmed	Hdac7 promotes lung tumorigenesis by inhibiting Stat3 activation.	HDAC7 STAT3	1.05e-05	2	113	2	29126425
Pubmed	Role of steroid 11 beta-hydroxylase and steroid 18-hydroxylase in the biosynthesis of glucocorticoids and mineralocorticoids in humans.	CYP11B1 CYP11B2	1.05e-05	2	113	2	1741400
Pubmed	CIB2 and CIB3 Regulate Stereocilia Maintenance and Mechanoelectrical Transduction in Mouse Vestibular Hair Cells.	CIB2 CIB3	1.05e-05	2	113	2	37001993
Pubmed	Effects of intron conversion in the human CYP11B2 gene on its transcription and blood pressure regulation in transgenic mice.	CYP11B1 CYP11B2	1.05e-05	2	113	2	32540969
Pubmed	Inhibition of aldosterone synthase (CYP11B2) by torasemide prevents atrial fibrosis and atrial fibrillation in mice.	CYP11B1 CYP11B2	1.05e-05	2	113	2	26047574
Pubmed	Aldosterone synthase knockout mouse as a model for sodium-induced endothelial sodium channel up-regulation in vascular endothelium.	CYP11B1 CYP11B2	1.05e-05	2	113	2	26324851
Pubmed	Microsatellite polymorphism analysis allows the individual assignment of the rat 11 beta-hydroxylase gene (Cyp11b1) and the rat aldosterone synthase gene (Cyp11b2) to chromosome 7 using rat x mouse somatic cell hybrids and identifies differences between and within various rat strains.	CYP11B1 CYP11B2	1.05e-05	2	113	2	7669222
Pubmed	Aldosterone-dependent and -independent regulation of the epithelial sodium channel (ENaC) in mouse distal nephron.	CYP11B1 CYP11B2	1.05e-05	2	113	2	22933298
Pubmed	Structural and functional analysis of the promoter region of the gene encoding mouse steroid 11 beta-hydroxylase.	CYP11B1 CYP11B2	1.05e-05	2	113	2	2783417
Pubmed	Cloning and expression of a cDNA for human cytochrome P-450aldo as related to primary aldosteronism.	CYP11B1 CYP11B2	1.05e-05	2	113	2	2256920
Pubmed	Association of DNA polymorphisms within the CYP11B2/CYP11B1 locus and postoperative hypertension risk in the patients with aldosterone-producing adenomas.	CYP11B1 CYP11B2	1.05e-05	2	113	2	20708777
Pubmed	Molecular genetic studies on the biosynthesis of aldosterone in humans.	CYP11B1 CYP11B2	1.05e-05	2	113	2	22217843
Pubmed	Mechanistic study of polychlorinated biphenyl 126-induced CYP11B1 and CYP11B2 up-regulation.	CYP11B1 CYP11B2	1.05e-05	2	113	2	16396990
Pubmed	[123 I]Iodometomidate for molecular imaging of adrenocortical cytochrome P450 family 11B enzymes.	CYP11B1 CYP11B2	1.05e-05	2	113	2	18397978
Pubmed	Glucocorticoid-suppressible hyperaldosteronism results from hybrid genes created by unequal crossovers between CYP11B1 and CYP11B2.	CYP11B1 CYP11B2	1.05e-05	2	113	2	1518866
Pubmed	Procollagen I-expressing renin cell precursors.	CYP11B1 CYP11B2	1.05e-05	2	113	2	23761669
Pubmed	Characterization of two genes encoding human steroid 11 beta-hydroxylase (P-450(11) beta).	CYP11B1 CYP11B2	1.05e-05	2	113	2	2592361
Pubmed	The subcellular redistribution of NLRC5 promotes angiogenesis via interacting with STAT3 in endothelial cells.	STAT3 NLRC5	1.05e-05	2	113	2	33754073
Pubmed	Aldosterone deficiency prevents high-fat-feeding-induced hyperglycaemia and adipocyte dysfunction in mice.	CYP11B1 CYP11B2	1.05e-05	2	113	2	23314847
Pubmed	Effect of variation in CYP11B1 and CYP11B2 on corticosteroid phenotype and hypothalamic-pituitary-adrenal axis activity in hypertensive and normotensive subjects.	CYP11B1 CYP11B2	1.05e-05	2	113	2	17980006
Pubmed	Association between aldosterone production and variation in the 11beta-hydroxylase (CYP11B1) gene.	CYP11B1 CYP11B2	1.05e-05	2	113	2	16984984
Pubmed	Evidence for local aldosterone synthesis in the large intestine of the mouse.	CYP11B1 CYP11B2	1.05e-05	2	113	2	35288482
Pubmed	Homeostatic responses in the adrenal cortex to the absence of aldosterone in mice.	CYP11B1 CYP11B2	1.05e-05	2	113	2	15731365
Pubmed	Critical role for Epac1 in inflammatory pain controlled by GRK2-mediated phosphorylation of Epac1.	GRK2 RAPGEF3	1.05e-05	2	113	2	26929333
Pubmed	Phenotypic consequences of variation across the aldosterone synthase and 11-beta hydroxylase locus in a hypertensive cohort: data from the MRC BRIGHT Study.	CYP11B1 CYP11B2	1.05e-05	2	113	2	17651452
Pubmed	Expression of CYP11B1 and CYP11B2 in adrenal adenoma correlates with clinical characteristics of primary aldosteronism.	CYP11B1 CYP11B2	1.05e-05	2	113	2	34743356
Pubmed	Polymorphisms in CYP11B2 and CYP11B1 genes associated with primary hyperaldosteronism.	CYP11B1 CYP11B2	1.05e-05	2	113	2	20339375
Pubmed	Genetic analyses of the chimeric CYP11B1/CYP11B2 gene in a Korean family with glucocorticoid-remediable aldosteronism.	CYP11B1 CYP11B2	1.05e-05	2	113	2	20808686
Pubmed	Electroacupuncture Attenuates Post-Inflammatory IBS-Associated Visceral and Somatic Hypersensitivity and Correlates With the Regulatory Mechanism of Epac1-Piezo2 Axis.	PIEZO2 RAPGEF3	1.05e-05	2	113	2	35865309
Pubmed	Aldosterone decreases glucose-stimulated insulin secretion in vivo in mice and in murine islets.	CYP11B1 CYP11B2	1.05e-05	2	113	2	21519965
Pubmed	Diagnosis of glucocorticoid-remediable aldosteronism in hypertensive children.	CYP11B1 CYP11B2	1.05e-05	2	113	2	21625068
Pubmed	Genetic screening for glucocorticoid-remediable aldosteronism (GRA): experience of three clinical centres in Poland.	CYP11B1 CYP11B2	1.05e-05	2	113	2	16110193
Pubmed	Chimeric CYP11B2/CYP11B1 causing 11β-hydroxylase deficiency in Chinese patients with congenital adrenal hyperplasia.	CYP11B1 CYP11B2	1.05e-05	2	113	2	26066897
Pubmed	STAT3 is involved in phosphatidic acid-induced Bcl-2 expression in HeLa cells.	BCL2 STAT3	1.05e-05	2	113	2	19287190
Pubmed	Cytotoxicity and decreased corticosterone production in adrenocortical Y-1 cells by 3-methylsulfonyl-DDE and structurally related molecules.	CYP11B1 CYP11B2	1.05e-05	2	113	2	18651133
Pubmed	A new presentation of the chimeric CYP11B1/CYP11B2 gene with low prevalence of primary aldosteronism and atypical gene segregation pattern.	CYP11B1 CYP11B2	1.05e-05	2	113	2	22083159
Pubmed	Editorial: polymorphisms in CYP11B genes and 11-hydroxylase activity.	CYP11B1 CYP11B2	1.05e-05	2	113	2	15699546
Pubmed	Cyp11b1 is induced in the murine gonad by luteinizing hormone/human chorionic gonadotropin and involved in the production of 11-ketotestosterone, a major fish androgen: conservation and evolution of the androgen metabolic pathway.	CYP11B1 CYP11B2	1.05e-05	2	113	2	18162527
Pubmed	Chronic activation of adrenal Gq signaling induces Cyp11b2 expression in the zona fasciculata and hyperaldosteronism.	CYP11B1 CYP11B2	1.05e-05	2	113	2	38341019
Pubmed	Adrenal CYP11B1/2 expression in primary aldosteronism: immunohistochemical analysis using novel monoclonal antibodies.	CYP11B1 CYP11B2	1.05e-05	2	113	2	24837548
Pubmed	Aldosterone deficiency in mice burdens respiration and accentuates diet-induced hyperinsulinemia and obesity.	CYP11B1 CYP11B2	1.05e-05	2	113	2	30046010
Pubmed	Familial and phenotypic associations of the aldosterone Renin ratio.	CYP11B1 CYP11B2	1.05e-05	2	113	2	19820005
Pubmed	Aldosterone deficiency and mineralocorticoid receptor antagonism prevent angiotensin II-induced cardiac, renal, and vascular injury.	CYP11B1 CYP11B2	1.05e-05	2	113	2	22622494
Pubmed	Mutation analysis of CYP11B1 and CYP11B2 in patients with increased 18-hydroxycortisol production.	CYP11B1 CYP11B2	1.05e-05	2	113	2	15062555
Pubmed	Disturbed homeostasis in sodium-restricted mice heterozygous and homozygous for aldosterone synthase gene disruption.	CYP11B1 CYP11B2	1.05e-05	2	113	2	17075030
Pubmed	Polymorphic variation in the 11beta-hydroxylase gene associates with reduced 11-hydroxylase efficiency.	CYP11B1 CYP11B2	1.05e-05	2	113	2	17075029
Pubmed	CYP11B2-CYP11B1 haplotypes associated with decreased 11 beta-hydroxylase activity.	CYP11B1 CYP11B2	1.05e-05	2	113	2	15507509
Pubmed	Polymorphism of CYP11B2 determines salt sensitivity in Japanese.	CYP11B1 CYP11B2	1.05e-05	2	113	2	17296872
Pubmed	Salt-sensitive blood pressure in mice with increased expression of aldosterone synthase.	CYP11B1 CYP11B2	1.05e-05	2	113	2	18039983
Pubmed	Cyp11b1 null mouse, a model of congenital adrenal hyperplasia.	CYP11B1 CYP11B2	1.05e-05	2	113	2	19029289
Pubmed	Genetic variation at the locus encompassing 11-beta hydroxylase and aldosterone synthase accounts for heritability in cortisol precursor (11-deoxycortisol) urinary metabolite excretion.	CYP11B1 CYP11B2	1.05e-05	2	113	2	15522937
Pubmed	The roles of cAMP and cAMP-dependent protein kinase in the expression of cholesterol side chain cleavage and steroid 11 beta-hydroxylase genes in mouse adrenocortical tumor cells.	CYP11B1 CYP11B2	3.13e-05	3	113	2	2546938
Pubmed	Kidney function in mice lacking aldosterone.	CYP11B1 CYP11B2	3.13e-05	3	113	2	16118390
Pubmed	Aldosterone-induced coronary dysfunction in transgenic mice involves the calcium-activated potassium (BKCa) channels of vascular smooth muscle cells.	CYP11B1 CYP11B2	3.13e-05	3	113	2	17984374
Pubmed	Identification and characterization of two upstream elements that regulate adrenocortical expression of steroid 11 beta-hydroxylase.	CYP11B1 CYP11B2	3.13e-05	3	113	2	2233742
Pubmed	Substrate-induced modulation of protein-protein interactions within human mitochondrial cytochrome P450-dependent system.	CYP11B1 CYP11B2	3.13e-05	3	113	2	33271253
Pubmed	The prolactin regulatory element-binding regulates of the 11beta-hydroxylase gene.	CYP11B1 CYP11B2	3.13e-05	3	113	2	18801336
Pubmed	Differential regulation of aldosterone synthase and 11beta-hydroxylase transcription by steroidogenic factor-1.	CYP11B1 CYP11B2	3.13e-05	3	113	2	11932209
Pubmed	GRKs and Epac1 Interaction in Cardiac Remodeling and Heart Failure.	GRK2 RAPGEF3	3.13e-05	3	113	2	33466800
Pubmed	Aldosterone postnatally, but not at birth, is required for optimal induction of renal mineralocorticoid receptor expression and sodium reabsorption.	CYP11B1 CYP11B2	3.13e-05	3	113	2	21467193
Pubmed	Coupling of Homologous Recombination and the Checkpoint by ATR.	ATR PALB2	3.13e-05	3	113	2	28089683
Pubmed	STAT3 interrupts ATR-Chk1 signaling to allow oncovirus-mediated cell proliferation.	ATR STAT3	3.13e-05	3	113	2	24639502
Pubmed	TIRC7 inhibits Th1 cells by upregulating the expression of CTLA‑4 and STAT3 in mice with acute graft‑versus‑host disease.	TCIRG1 STAT3	3.13e-05	3	113	2	32319655
Pubmed	Expression of genes related to multiple drug resistance and apoptosis in acute leukemia: response to induction chemotherapy.	ABCC1 BCL2	3.13e-05	3	113	2	22037714
Pubmed	Acute inflammation induces insulin-like growth factor-1 to mediate Bcl-2 and Muc5ac expression in airway epithelial cells.	BCL2 MUC5AC	3.13e-05	3	113	2	22878411
Pubmed	Expression of the steroidogenic enzyme P450scc in the central and peripheral nervous systems during rodent embryogenesis.	CYP11B1 CYP11B2	3.13e-05	3	113	2	7750493
Pubmed	Reversal of multidrug resistance by icaritin in doxorubicin-resistant human osteosarcoma cells.	ABCC1 STAT3	3.13e-05	3	113	2	29425587
Pubmed	Antiaging Gene Klotho Regulates Adrenal CYP11B2 Expression and Aldosterone Synthesis.	CYP11B1 CYP11B2	3.13e-05	3	113	2	26471128
Pubmed	Increased drug resistance in breast cancer by tumor-associated macrophages through IL-10/STAT3/bcl-2 signaling pathway.	BCL2 STAT3	3.13e-05	3	113	2	25572805
Pubmed	Tip60 is a co-repressor for STAT3.	HDAC7 STAT3	3.13e-05	3	113	2	12551922
Pubmed	Molecular Recognition in Mitochondrial Cytochromes P450 That Catalyze the Terminal Steps of Corticosteroid Biosynthesis.	CYP11B1 CYP11B2	3.13e-05	3	113	2	28355486
Pubmed	Immune escape of colorectal tumours via local LRH-1/Cyp11b1-mediated synthesis of immunosuppressive glucocorticoids.	CYP11B1 CYP11B2	3.13e-05	3	113	2	36861295
Pubmed	Mediator modulates Gli3-dependent Sonic hedgehog signaling.	GLI3 MED12	3.13e-05	3	113	2	17000779
Pubmed	Adrenal-Specific KO of the Circadian Clock Protein BMAL1 Alters Blood Pressure Rhythm and Timing of Eating Behavior.	CYP11B1 CYP11B2	3.13e-05	3	113	2	36778748
Pubmed	Neurosteroid biosynthesis: genes for adrenal steroidogenic enzymes are expressed in the brain.	CYP11B1 CYP11B2	3.13e-05	3	113	2	8111631
Pubmed	TEFM (c17orf42) is necessary for transcription of human mtDNA.	TEFM DHX30	3.13e-05	3	113	2	21278163
Pubmed	IL-17-mediated Bcl-2 expression regulates survival of fibroblast-like synoviocytes in rheumatoid arthritis through STAT3 activation.	BCL2 STAT3	3.13e-05	3	113	2	23421940
Pubmed	Interaction of CYP11B1 (cytochrome P-45011 beta) with CYP11A1 (cytochrome P-450scc) in COS-1 cells.	CYP11B1 CYP11B2	3.13e-05	3	113	2	10411633
Pubmed	Differential effects of high and low steroidogenic factor-1 expression on CYP11B2 expression and aldosterone production in adrenocortical cells.	CYP11B1 CYP11B2	3.13e-05	3	113	2	18974272
Pubmed	Different isozymes of mouse 11 beta-hydroxylase produce mineralocorticoids and glucocorticoids.	CYP11B1 CYP11B2	3.13e-05	3	113	2	1686470
Pubmed	Targeted regulationof STAT3 by miR-29a in mediating Taxol resistance of nasopharyngeal carcinoma cell line CNE-1.	BCL2 STAT3	3.13e-05	3	113	2	29914005
Pubmed	Sam68 mediates high glucose‑induced podocyte apoptosis through modulation of Bax/Bcl‑2.	BCL2 KHDRBS1	3.13e-05	3	113	2	31485651
Pubmed	Mislocalization of protein kinase A drives pathology in Cushing's syndrome.	CYP11B1 CYP11B2	3.13e-05	3	113	2	35830806
Pubmed	Sorafenib with ASC-J9® synergistically suppresses the HCC progression via altering the pSTAT3-CCL2/Bcl2 signals.	BCL2 STAT3	3.13e-05	3	113	2	27668844
Pubmed	[Effects of cucurbitacin B on cell proliferation and apoptosis in Hep-2 cells].	BCL2 STAT3	3.13e-05	3	113	2	18652313
Pubmed	STAT3 regulated ATR via microRNA-383 to control DNA damage to affect apoptosis in A431 cells.	ATR STAT3	3.13e-05	3	113	2	26261078
Pubmed	MED12 mutations link intellectual disability syndromes with dysregulated GLI3-dependent Sonic Hedgehog signaling.	GLI3 MED12	3.13e-05	3	113	2	23091001
Pubmed	Control of renin secretion from kidneys with renin cell hyperplasia.	CYP11B1 CYP11B2	3.13e-05	3	113	2	24285498
Cytoband	4q28	PLK4 RAB33B	2.14e-04	9	113	2	4q28
Cytoband	12q13.1	HDAC7 RAPGEF3	3.90e-04	12	113	2	12q13.1
Cytoband	18p11.22	PIEZO2 MTCL1	7.97e-04	17	113	2	18p11.22
GeneFamily	Cytochrome P450 family 11	CYP11B1 CYP11B2	5.50e-05	3	78	2	1007
GeneFamily	Olfactory receptors, family 8	OR8U1 OR8U9 OR8U8 OR8G5	5.86e-05	49	78	4	155
Coexpression	GSE8685_IL2_STARVED_VS_IL15_ACT_IL2_STARVED_CD4_TCELL_UP	GAPVD1 CIB3 FBXL3 ADD3 EXOC5 KANSL1 EPC1	2.28e-05	199	111	7	M326
Coexpression	GSE17580_UNINFECTED_VS_S_MANSONI_INF_TREG_UP	CDK12 ATG2B BCL2 FBXL3 RNF167 MDN1 MS4A1	2.28e-05	199	111	7	M3677
Coexpression	GSE20366_EX_VIVO_VS_DEC205_CONVERSION_DN	BCL2 QRICH1 RBM39 ZBTB39 MS4A1 GLI3 RAB33B	2.36e-05	200	111	7	M4318
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-Myeloid_Dendritic_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SETD1A FGD2 MYO9A KIAA1549 PALB2 MDN1 EPC1	2.89e-07	175	111	7	bb058e714d21a0ec8532eaf3c7dd2faf78016bc0
ToppCell	Adult-Immune-mast_cell\|Adult / Lineage, Cell type, age group and donor	CIB2 KIAA1549 SLC24A3 PANX3 SLC45A3 MTCL1	3.18e-06	161	111	6	44f5c0256b3ce264a6c7b62740f32dcd45ee052d
ToppCell	Healthy_Control-Myeloid-Mast\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	CIB2 OBSCN SLC24A3 STRIP2 PIEZO2 SLC45A3	5.13e-06	175	111	6	ca187074adcc9b8bd0fa270e2ede1564c8e6c6cf
ToppCell	Healthy_Control-Myeloid-Mast-\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	CIB2 OBSCN SLC24A3 STRIP2 PIEZO2 SLC45A3	5.13e-06	175	111	6	eadbbcdf2aef4cee268bc70a7a2c4175d898953b
ToppCell	Tracheal-10x3prime_v2-Immune_Lymphocytic-B-B_cell-B_naive\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	FGD2 ZNF195 BCL2 GIT2 MS4A1	5.48e-06	101	111	5	86acaa2502f61baa714ae988b73e3e73a71e897e
ToppCell	Control-B_intermediate-6\|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)	TCIRG1 RNF213 MS4A1 NLRC5 BCAR3 PREX1	7.97e-06	189	111	6	11cb9a16f1de8f60af2073ed7ea6d4f41c02f299
ToppCell	CD8+_Memory_T_cell-CV-7\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	GAPVD1 VPS13C RNF213 URB1 SYNE3 TBCK	8.46e-06	191	111	6	9454f642c3621370fa23640b631301346b300950
ToppCell	COVID-19\|World / Disease, condition lineage and cell class	VPS13C RNF213 BCL2 RBM39 STAT3 EPC1	1.10e-05	200	111	6	7dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCell	COVID-19-Mast_cells-Mast_cells\|COVID-19 / group, cell type (main and fine annotations)	KIAA1549 SLC24A3 NBEA SLC45A3 MTCL1	4.48e-05	156	111	5	bc10b94673184ef384c6665b16a1209a8975a4f1
ToppCell	10x5'-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8\|bone_marrow / Manually curated celltypes from each tissue	ABCC1 RNF213 RBM39 STAT3 KANSL1	4.48e-05	156	111	5	1545169694f686d28648a68b552c2ae606599d66
ToppCell	COVID-19-Mast_cells\|COVID-19 / group, cell type (main and fine annotations)	KIAA1549 SLC24A3 NBEA SLC45A3 MTCL1	4.48e-05	156	111	5	159504d43421ee83b9ab484816333ae549c9c2fd
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PIEZO2 HECW2 NAV1 NLRC5 PREX1	4.90e-05	159	111	5	d3f81ba22160568ccaa6d2b04ebfd30630f9a6db
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-plasmacytoid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FGD2 OBSCN PALB2 URB1 RAB33B	5.20e-05	161	111	5	ed93cb6c133855a5c244821e1a260aae8ab4df9a
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-Plasmacytoid_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FGD2 OBSCN PALB2 URB1 RAB33B	5.20e-05	161	111	5	0089d7bb305c592392791862a3341fc92af8f3e2
ToppCell	droplet-Lung-nan-3m-Myeloid-Ccr7+_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATR CARMIL3 SQLE STRIP2 NLRC5	5.68e-05	164	111	5	78de403446fe0eb375c82ff1832cc5fbb8e20afa
ToppCell	nucseq-Immune-Hematopoietic-Granulocytic\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	KIAA1549 SLC24A3 NBEA SLC45A3 MTCL1	5.85e-05	165	111	5	37615622c736e43260c38016e7c9e565ac97a3e8
ToppCell	nucseq-Immune-Hematopoietic-Granulocytic-Mast/Basophil\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	KIAA1549 SLC24A3 NBEA SLC45A3 MTCL1	5.85e-05	165	111	5	640bb71e74a61df2fcb01ceeabe4c493ef836b21
ToppCell	nucseq-Immune-Hematopoietic\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	KIAA1549 SLC24A3 NBEA SLC45A3 MTCL1	5.85e-05	165	111	5	f3df74b5763130c71c0a482a3a23f6b22acc2892
ToppCell	moderate-Myeloid-Mast_cell\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	KIAA1549 SLC24A3 PIEZO2 SLC45A3 MTCL1	6.02e-05	166	111	5	c3835b424c63bf11a4e2c47635dc3787fc4a637a
ToppCell	E16.5-Endothelial-Endothelial_lymphatic\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RXRA MMRN1 SYNE3 L3MBTL1 SLC45A3	6.19e-05	167	111	5	b93103a868fba63a8910bffb690a6242b9252833
ToppCell	E16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RXRA MMRN1 SYNE3 L3MBTL1 SLC45A3	6.19e-05	167	111	5	fcd583b1efd0ac883379982ea8e6c54f2c0be268
ToppCell	E16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RXRA MMRN1 SYNE3 L3MBTL1 SLC45A3	6.19e-05	167	111	5	f6bc63138b7239211fa5f27a8dc799b6e022c0f8
ToppCell	E16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RXRA MMRN1 SYNE3 L3MBTL1 SLC45A3	6.19e-05	167	111	5	26cd8ee5e826e71eaf58d10a906543a6932fb3f9
ToppCell	5'-Adult-Appendix-Hematopoietic-Myeloid-Lymphoid_DC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FGD2 CIB3 TENM2 CCNA1 NAV1	6.19e-05	167	111	5	8b223333c0c7a85b5a1af6f2f5b12ee0d94357f6
ToppCell	Control-Mast_cells\|Control / group, cell type (main and fine annotations)	KIAA1549 SLC24A3 NBEA SLC45A3 MTCL1	6.55e-05	169	111	5	fdb9abca1d0f4fdc32dd8ac6231651ef34aa5afb
ToppCell	droplet-Lung-nan-18m-Myeloid-Plasmacytoid_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FOXR1 SQLE PRKCG MUC5AC RAB33B	6.73e-05	170	111	5	749144a1a869a6bf9acdd227184319083367dc3f
ToppCell	Control-Mast_cells-Mast_cells\|Control / group, cell type (main and fine annotations)	KIAA1549 SLC24A3 NBEA SLC45A3 MTCL1	6.73e-05	170	111	5	c80f6d29096c372da95a8407f402349ff1bb7018
ToppCell	droplet-Lung-nan-18m-Myeloid-plasmacytoid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FOXR1 SQLE PRKCG MUC5AC RAB33B	6.73e-05	170	111	5	25d60a62e8f99c31ab64fe6a0c07ccca3df1a7ee
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	RNF213 RBM39 STAT3 KANSL1 NLRC5	6.92e-05	171	111	5	2e9a20f8980b78325c52065a9c14ab3656267c05
ToppCell	droplet-Lung-18m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FOXR1 SQLE PRKCG MUC5AC RAB33B	7.12e-05	172	111	5	422d311bba2dd5d8bece4e96ee8c86e78086b62d
ToppCell	droplet-Lung-18m-Hematologic-myeloid-plasmacytoid_dendritic_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FOXR1 SQLE PRKCG MUC5AC RAB33B	7.12e-05	172	111	5	1abb6fbb28c8aff384540493d0f70eeacaa751f4
ToppCell	5'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-CLC+_Mast_cell\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ABCC1 SLC24A3 SLC45A3 CCNA1 OR8G5	7.12e-05	172	111	5	2ab720a4c96073339a1f8b95ec7699682df98acf
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FMO1 STRIP2 PIEZO2 HECW2 NAV1	7.93e-05	176	111	5	269326c2bf44a9003d95bc6dbc839f08f25737ca
ToppCell	3'_v3-lymph-node_spleen-Myeloid_Dendritic-DC2\|lymph-node_spleen / Manually curated celltypes from each tissue	CFAP47 FGD2 CIB3 NAV1 MUC5AC	7.93e-05	176	111	5	72a3bbab0540ae3e3c94b9573cdb9298a024dbc4
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FOXR1 PIEZO2 HECW2 NAV1 PREX1	7.93e-05	176	111	5	dc5a22f9d1347f157bdd93e6e5769b983deccf1a
ToppCell	PND14-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFAP47 TBC1D31 CCNA1 PLK4 DEUP1	8.82e-05	180	111	5	5c9d2d44d840cd4ec7d42d43446ba2b689e7ec43
ToppCell	PND14-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFAP47 TBC1D31 CCNA1 PLK4 DEUP1	8.82e-05	180	111	5	c60e74fbbd815a0251253a19dc520a254b2e1762
ToppCell	droplet-Liver-Npc-21m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NBEA ZBTB39 USH1G HECW2 NAV1	9.29e-05	182	111	5	dc55de945c6f78f32eb3a1b3520835eb8417e068
ToppCell	10x3'2.3-week_14-16-Hematopoietic-HSC/MPP_and_pro-LMPP\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	BCL2 CHI3L2 L3MBTL1 TBCK MAP3K10	9.29e-05	182	111	5	69b5cae6fe3bbb0fc60bd2f71b6cfa6cbb0b00ee
ToppCell	COPD-Myeloid-Mast\|World / Disease state, Lineage and Cell class	KIAA1549 SLC24A3 STRIP2 SLC45A3 MTCL1	9.29e-05	182	111	5	68a1e7b804f309bfd6c23d65fad20a9a962712ae
ToppCell	droplet-Liver-Npc-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NBEA ZBTB39 USH1G HECW2 NAV1	9.29e-05	182	111	5	010a7364da46101cb5068891fd7bc712ea8f13bd
ToppCell	IPF-Myeloid-Mast\|World / Disease state, Lineage and Cell class	ABCC1 KIAA1549 SLC24A3 SLC45A3 MTCL1	9.78e-05	184	111	5	7aefa182acad5a53c730945fec85329d7168606a
ToppCell	IPF-Myeloid-Mast\|IPF / Disease state, Lineage and Cell class	ABCC1 KIAA1549 SLC24A3 SLC45A3 MTCL1	9.78e-05	184	111	5	c3baf21f10b45cf91ac99997a59f353bcf3de8b7
ToppCell	10x5'v1-week_14-16-Myeloid_neutrophil-granulo-eo/baso/mast-eosinophil\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	ABCC1 SLC24A3 BCL2 SLC45A3 CCNA1	9.78e-05	184	111	5	ce31684772e47a294155f368e50b49753f7c8e87
ToppCell	control-Myeloid-Eosinophils\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	SLC24A3 BCL2 SLC45A3 CCNA1 BCAR3	9.78e-05	184	111	5	fad517d047e8eaeaa5bd4f311d770880568dd13c
ToppCell	droplet-Heart-4Chambers-21m-Endothelial-leukocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCIRG1 MMRN1 MDN1 SLC45A3 SLC10A6	1.00e-04	185	111	5	bb5a4cf93534b9bcd0923f314c389d571e91e7f8
ToppCell	(4)_Mast_cells\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	KIAA1549 SLC24A3 STRIP2 MS4A1 SLC45A3	1.00e-04	185	111	5	c91e1081e630a61c18f6af6d198bfcf296746852
ToppCell	(4)_Mast_cells\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	KIAA1549 SLC24A3 STRIP2 MS4A1 SLC45A3	1.00e-04	185	111	5	3dd5d2237ab50b13a41c12f85e1b79cd72ea567b
ToppCell	COPD-Myeloid-Mast\|COPD / Disease state, Lineage and Cell class	KIAA1549 SLC24A3 STRIP2 SLC45A3 MTCL1	1.03e-04	186	111	5	def6f0f284acc2154738574c8c5d3d2a5ef1f208
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	VPS13C DGKB RXRA GRK2 NAV1	1.03e-04	186	111	5	23b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell	10x5'-Lung-Mast\|Lung / Manually curated celltypes from each tissue	KIAA1549 SLC24A3 NBEA SLC45A3 MTCL1	1.05e-04	187	111	5	f8ac5ca5cbe9c6f3d8c0fffc20fe08ca1aea43c0
ToppCell	10x5'-Lung-Mast-Mast_cells\|Lung / Manually curated celltypes from each tissue	KIAA1549 SLC24A3 NBEA SLC45A3 MTCL1	1.05e-04	187	111	5	da275d2c774b3e6a8ed77f777dd0676ecf2ddd2c
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	VPS13C RNF213 INO80D RBM39 KANSL1	1.08e-04	188	111	5	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	Mast_cells\|World / lung cells shred on cell class, cell subclass, sample id	KIAA1549 SLC24A3 MS4A1 SLC45A3 MTCL1	1.08e-04	188	111	5	229d24b87e945c4d543d11ac70761e45175ba0e5
ToppCell	3'-Distal_airway-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KIAA1549 SLC24A3 STRIP2 SLC45A3 MTCL1	1.11e-04	189	111	5	f3cb1a8ddf7a4a95fb1b6e8fe5aa63ef037ca7a6
ToppCell	Control-Endothelial-VE_Capillary_B\|Endothelial / Disease state, Lineage and Cell class	KIAA1549 HECW2 NAV1 BCAR3 PREX1	1.14e-04	190	111	5	7f3f419fffe02934b6f27b697f7a6401072491ed
ToppCell	(04)_Pre-ciliated\|World / shred by cell type and Timepoint	TBC1D31 CCNA1 POC5 PLK4 DEUP1	1.16e-04	191	111	5	37cf121e6e80760c8519075b7845b9029958a988
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FMO1 ADD3 PIEZO2 RAPGEF3 NAV1	1.16e-04	191	111	5	718330bb97fe8a1ffd0c82e9af23311a32eacfe1
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FMO1 ADD3 PIEZO2 RAPGEF3 NAV1	1.16e-04	191	111	5	454034ad940377ee079afa8ce33f8e0bdeaf44f8
ToppCell	10x3'2.3-week_17-19-Myeloid_neutrophil-granulo-eo/baso/mast-mast_cell\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	ABCC1 KIAA1549 SLC24A3 SLC45A3 CCNA1	1.19e-04	192	111	5	758ca0dacf313787effda36e6d1adb809e5b3a4e
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AMPD2 FMO1 CARMIL3 SQLE SEC23B	1.22e-04	193	111	5	471e65f02937bc18d7c5facdacdf1df58cf0f839
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AMPD2 FMO1 CARMIL3 SQLE SEC23B	1.22e-04	193	111	5	fe451b3295d77b2bd1ac25cf29310c85835a45fe
ToppCell	CF-Lymphoid\|CF / Disease state, Lineage and Cell class	ATR FGD2 MDN1 MS4A1 TBCK	1.22e-04	193	111	5	11de07d13a7da223990b56fa89ba7fc1c3dd0122
ToppCell	10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_cytotoxic-C\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	RNF213 HDAC7 BTN2A1 MDN1 MTCL1	1.28e-04	195	111	5	83c125223e7ca0f08a31414b3a16347912564765
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC1 PIEZO2 HECW2 NAV1 PREX1	1.28e-04	195	111	5	23ced69fd904f1d4114b1a7f99f4b5f65ea8824b
ToppCell	distal-Hematologic-Basophil/Mast_1-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	KIAA1549 SLC24A3 STRIP2 SLC45A3 MTCL1	1.28e-04	195	111	5	4f83449fce3717518e2acbba1a4b3bea765c0bdb
ToppCell	facs-Lung-nan-3m-Endothelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMO1 MMRN1 PIEZO2 SLC45A3 HECW2	1.28e-04	195	111	5	7f9b7f15006610ad591063d90e90367bd6083c7f
ToppCell	Adult-Immune-monocyte-D122\|Adult / Lineage, Cell type, age group and donor	AMPD2 FGD2 TCIRG1 GRK2 PREX1	1.31e-04	196	111	5	16b0acb6157534938ca83d4e909471e33a7d3c52
ToppCell	10x5'v1-week_14-16-Myeloid_neutrophil-granulo-eo/baso/mast-basophil\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	ABCC1 SLC24A3 RUSC2 SLC45A3 CCNA1	1.31e-04	196	111	5	5bb8653af62334ded8aad48b24b64d7b54bc3cd5
ToppCell	moderate-Lymphoid-Treg\|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	VPS13C RNF213 RBM39 TBC1D31 EPC1	1.31e-04	196	111	5	9152f4a8a27ff4ee28f231c5ad00eb2edd9ea6da
ToppCell	COVID-19_Mild\|World / Disease group, lineage and cell class	VPS13C RNF213 RBM39 GRK2 KANSL1	1.35e-04	197	111	5	5c33454b10023decd2f5ccda9229b6512659711e
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Dendritic_cell-DC_activated\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FGD2 CIB3 STRIP2 NAV1 MED12	1.35e-04	197	111	5	68d8546dfe7dffd017756a11d3333061f576d0ef
ToppCell	PBMC-Mild\|PBMC / Location, Disease Group, Cell group, Cell class (2021.03.09)	VPS13C RNF213 RBM39 GRK2 KANSL1	1.38e-04	198	111	5	44417089b62056269cac38d3134ff209c05b7007
ToppCell	Tracheal-NucSeq-Immune_Myeloid-Mast_cell-Mast_cell\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	KIAA1549 SLC24A3 SLC45A3 MTCL1 OR8G5	1.38e-04	198	111	5	cc5ca64749e2f4f1d373d9472824df85741702b7
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Proliferating\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	ADD3 TBC1D31 ARHGEF39 CCNA1 PLK4	1.38e-04	198	111	5	629d674a9c9108c1acb3f7af57bbdbf34bb0528e
ToppCell	Tracheal-NucSeq-Immune_Myeloid-Mast_cell\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	KIAA1549 SLC24A3 SLC45A3 MTCL1 OR8G5	1.38e-04	198	111	5	d4d66f19df078bfc3a83d4664aaf9c7789bde1a5
ToppCell	PBMC-Mild\|PBMC / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	VPS13C RNF213 RBM39 GRK2 KANSL1	1.38e-04	198	111	5	28ef3fc4c17dcb765537b75917f7db78baa522db
ToppCell	healthy_donor-Lymphocytic\|healthy_donor / Disease condition, Lineage, Cell class and subclass	RNF213 BCL2 ADD3 MS4A1 NLRC5	1.41e-04	199	111	5	2841e16d54acd344ba454f024e285c28abc37319
ToppCell	Severe-B_intermediate-6\|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)	FGD2 ADD3 MS4A1 NLRC5 PREX1	1.41e-04	199	111	5	bf6ebb63ab361d9d1946225894d7be433e9befab
ToppCell	Bronchial-10x5prime-Immune_Myeloid-Myeloid-Megakaryocyte\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	KIAA1549 SLC24A3 RUSC2 PIEZO2 SLC45A3	1.41e-04	199	111	5	6e7f7214317f2af2ba8523df9896f54b7294d58a
ToppCell	Bronchial-10x5prime-Immune_Myeloid-Myeloid\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	KIAA1549 SLC24A3 RUSC2 PIEZO2 SLC45A3	1.41e-04	199	111	5	5f499595597c10857bba8272f62afe4d32d733ac
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-CD4+_T_activated\|COVID-19_Mild / Disease, condition lineage and cell class	OBSCN RNF213 BCL2 ADD3 MDN1	1.44e-04	200	111	5	d9e8a0d047d4403fb7265fde7448e23a7780785c
ToppCell	Parenchymal-10x5prime-Immune_Myeloid-Mast_cell-Mast_cell\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	KIAA1549 SLC24A3 STRIP2 SLC45A3 MTCL1	1.44e-04	200	111	5	8943278190f42016ee914e584d1b6b9aeaf7c73f
ToppCell	Parenchymal-10x5prime-Immune_Myeloid-Mast_cell\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	KIAA1549 SLC24A3 STRIP2 SLC45A3 MTCL1	1.44e-04	200	111	5	ea52df18400550b65de142d03b3b0963436e03d9
ToppCell	343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	FBXL3 RNF167 GRK2 TRMT61B	1.60e-04	109	111	4	cc43c221487a712546917cc3253c158a1fc1fd7a
ToppCell	(05)_Ciliated-(3)_72hpi\|(05)_Ciliated / shred by cell type and Timepoint	TBC1D31 CCNA1 PREX1 PLK4	1.84e-04	113	111	4	eaa5bc8f8183b353ee1e7618e99220eb3684cd60
Drug	Hesperetin [520-33-2]; Up 200; 13.2uM; PC3; HG-U133A	SQLE GIT2 PIGZ RUSC2 VAC14 RNF167 ZBTB39 MED12	5.25e-06	197	110	8	1947_UP
Drug	2,2',3,3',4,6'-hexachlorobiphenyl	CYP11B1 CYP11B2 BCL2	6.04e-06	8	110	3	ctd:C094859
Drug	cyadox	CYP11B1 CYP11B2	2.31e-05	2	110	2	ctd:C020728
Drug	18-hydroxydeoxycorticosterone	CYP11B1 CYP11B2	2.31e-05	2	110	2	ctd:C042509
Drug	Phenoxybenzamine hydrochloride [63-92-3]; Down 200; 11.8uM; MCF7; HT_HG-U133A	SLC24A3 CTDSP1 NBEA BCL2 ADD3 PPP2R3A GLI3	3.06e-05	183	110	7	5613_DN
Drug	0179445-0000 [211246-22-9]; Down 200; 10uM; MCF7; HT_HG-U133A	NBEA BCL2 GIT2 PPP2R3A TBC1D31 FBXL18 MTCL1	3.28e-05	185	110	7	4755_DN
Drug	Clomiphene citrate (Z,E) [50-41-9]; Down 200; 6.6uM; PC3; HT_HG-U133A	INO80D HDAC7 KPTN URB1 ZBTB39 L3MBTL1 PLK4	4.59e-05	195	110	7	6648_DN
Drug	dalcetrapib	CYP11B1 CYP11B2 STAT3	4.79e-05	15	110	3	ctd:C411602
Drug	Ursolic acid [77-52-1]; Down 200; 8.8uM; PC3; HT_HG-U133A	SQLE GIT2 HDAC7 BTN2A1 VAC14 TMEM161A GLI3	4.90e-05	197	110	7	2067_DN
Drug	estradiol, USP; Up 200; 0.01uM; HL60; HG-U133A	GIT2 VAC14 TMEM161A TBC1D31 MS4A1 PLK4 SEC23B	4.90e-05	197	110	7	387_UP
Drug	STOCK1N-35696; Down 200; 15uM; MCF7; HT_HG-U133A	SQLE SLC24A3 GIT2 INO80D ADD3 GRK2 MED12	4.90e-05	197	110	7	6577_DN
Drug	Mephenesin [59-47-2]; Up 200; 22uM; HL60; HT_HG-U133A	BCL2 INO80D URB1 FBXL18 L3MBTL1 KHDRBS1 PLK4	5.05e-05	198	110	7	2342_UP
Drug	Flunarizine dihydrochloride [30484-77-6]; Down 200; 8.4uM; MCF7; HT_HG-U133A	MYO9A BCL2 GIT2 RXRA VAC14 TMEM161A MTCL1	5.05e-05	198	110	7	7013_DN
Drug	Pepstatin A [26305-03-3]; Up 200; 5.8uM; MCF7; HT_HG-U133A	MYO9A SLC24A3 BCL2 RUSC2 PPP2R3A MUC5AC PLK4	5.22e-05	199	110	7	3264_UP
Drug	genistein; Up 200; 10uM; MCF7; HG-U133A	PIGZ VAC14 TMEM161A RNF167 ZBTB39 KHDRBS1 RAB33B	5.22e-05	199	110	7	638_UP
Drug	FK-506; Up 200; 1uM; MCF7; HG-U133A	GAPVD1 GIT2 PIGZ BTN2A1 STAT3 TMEM161A PLK4	5.39e-05	200	110	7	378_UP
Drug	Naphazoline hydrochloride [550-99-2]; Down 200; 16.2uM; HL60; HG-U133A	MYO9A VPS13C INO80D BTN2A1 GRK2 CCNA1 SEC23B	5.39e-05	200	110	7	1966_DN
Disease	Glucocorticoid-remediable aldosteronism	CYP11B1 CYP11B2	1.23e-05	2	104	2	C1260386
Disease	adrenal cortical adenoma (is_marker_for)	CYP11B1 CYP11B2	1.23e-05	2	104	2	DOID:0050891 (is_marker_for)
Disease	Squamous cell carcinoma of the head and neck	ABCC1 STAT3 TBCK CCNA1	3.46e-05	52	104	4	C1168401
Disease	congenital adrenal hyperplasia (implicated_via_orthology)	CYP11B1 CYP11B2	3.68e-05	3	104	2	DOID:0050811 (implicated_via_orthology)
Disease	Malignant neoplasm of breast	ABCC1 OBSCN BCL2 HDAC7 PALB2 STAT3 ZCCHC14 TMEM161A KCNJ1 SLC10A6 NLRC5 BCAR3 MED12	1.04e-04	1074	104	13	C0006142
Disease	primary hyperaldosteronism (is_implicated_in)	CYP11B1 CYP11B2	1.22e-04	5	104	2	DOID:446 (is_implicated_in)
Disease	pontocerebellar hypoplasia (implicated_via_orthology)	AMPD2 TBC1D23	1.22e-04	5	104	2	DOID:0060264 (implicated_via_orthology)
Disease	Conn Syndrome	CYP11B1 CYP11B2	1.83e-04	6	104	2	C1384514
Disease	Usher Syndrome, Type I	CIB2 USH1G	1.83e-04	6	104	2	C1568247
Disease	Hyperaldosteronism	CYP11B1 CYP11B2	1.83e-04	6	104	2	C0020428
Disease	Intellectual Disability	SETD1A NBEA QRICH1 FBXL3 KANSL1 SCN1A PRKCG TBC1D23	1.89e-04	447	104	8	C3714756
Disease	protocadherin alpha-7 measurement	CYP11B1 CYP11B2	2.55e-04	7	104	2	EFO_0801973
Disease	hippocampal CA3 volume	CFAP47 KANSL1 GLI3	2.79e-04	36	104	3	EFO_0009395
Disease	Prostatic Neoplasms	ATR CDK12 CYP11B2 BCL2 RXRA PALB2 STAT3 DHX30 MED12	3.36e-04	616	104	9	C0033578
Disease	Malignant neoplasm of prostate	ATR CDK12 CYP11B2 BCL2 RXRA PALB2 STAT3 DHX30 MED12	3.36e-04	616	104	9	C0376358
Disease	protein FAM163B measurement	CYP11B1 CYP11B2	4.36e-04	9	104	2	EFO_0802936
Disease	nasopharynx carcinoma (is_marker_for)	ATR BCL2 STAT3	4.74e-04	43	104	3	DOID:9261 (is_marker_for)
Disease	androstenedione measurement	CYP11B1 CYP11B2	5.44e-04	10	104	2	EFO_0007972
Disease	allergic rhinitis (biomarker_via_orthology)	BCL2 MUC5AC	5.44e-04	10	104	2	DOID:4481 (biomarker_via_orthology)
Disease	cell growth regulator with EF hand domain protein 1 measurement	CYP11B1 CYP11B2	6.63e-04	11	104	2	EFO_0801461
Disease	3-hydroxyanthranilate 3,4-dioxygenase measurement	CYP11B1 CYP11B2	6.63e-04	11	104	2	EFO_0021862
Disease	colon cancer (implicated_via_orthology)	ATR BCL2	6.63e-04	11	104	2	DOID:219 (implicated_via_orthology)
Disease	gastric ulcer (implicated_via_orthology)	BCL2 MUC5AC	1.09e-03	14	104	2	DOID:10808 (implicated_via_orthology)
Disease	Lymphoma, Follicular, Grade 2	BCL2 RRAGC	1.25e-03	15	104	2	C1956132
Disease	Lymphoma, Follicular, Grade 3	BCL2 RRAGC	1.25e-03	15	104	2	C1956131
Disease	Lymphoma, Follicular, Grade 1	BCL2 RRAGC	1.25e-03	15	104	2	C1956130
Disease	Lymphoma, Large-Cell, Follicular	BCL2 RRAGC	1.25e-03	15	104	2	C0079745
Disease	Lymphoma, Small Cleaved-Cell, Follicular	BCL2 RRAGC	1.25e-03	15	104	2	C0079765
Disease	Lymphoma, Mixed-Cell, Follicular	BCL2 RRAGC	1.25e-03	15	104	2	C0079758
Disease	impotence (implicated_via_orthology)	BCL2 GRK2	1.25e-03	15	104	2	DOID:1875 (implicated_via_orthology)
Disease	basophil measurement	ABCC1 BCL2 CCNA1	1.26e-03	60	104	3	EFO_0803539
Disease	ovarian neoplasm	ATR CDK12 STAT3 KANSL1	1.32e-03	134	104	4	C0919267
Disease	Malignant neoplasm of ovary	ATR CDK12 STAT3 KANSL1	1.43e-03	137	104	4	C1140680
Disease	Pontoneocerebellar hypoplasia	AMPD2 TBC1D23	1.43e-03	16	104	2	cv:C1261175
Disease	pre-malignant neoplasm (biomarker_via_orthology)	STAT3 GLI3	1.62e-03	17	104	2	DOID:0060071 (biomarker_via_orthology)
Disease	stomach cancer (is_marker_for)	CDK12 NBEA BCL2 STAT3	1.63e-03	142	104	4	DOID:10534 (is_marker_for)
Disease	mean corpuscular hemoglobin concentration	ABCC1 ATR CDK12 CTDSP1 BCL2 URB2 HDAC7 STAT3 HECW2 PREX1 PLK4	1.80e-03	1105	104	11	EFO_0004528
Disease	migraine disorder, systolic blood pressure	RNF213 SLC24A3	1.81e-03	18	104	2	EFO_0006335, MONDO_0005277
Disease	Bone marrow hypocellularity	PALB2 MYSM1	1.81e-03	18	104	2	C1855710
Disease	mean reticulocyte volume	SETD1A ABCC1 ATR CYP11B1 BCL2 URB2 HDAC7 KANSL1 PREX1	2.08e-03	799	104	9	EFO_0010701
Disease	executive function measurement	SLC24A3 PIEZO2 CCNA1 NAV1 NLRC5 PREX1	2.19e-03	376	104	6	EFO_0009332
Disease	atherosclerosis (biomarker_via_orthology)	BCL2 STAT3	2.24e-03	20	104	2	DOID:1936 (biomarker_via_orthology)
Disease	Lymphoma, Follicular	BCL2 RRAGC	2.24e-03	20	104	2	C0024301
Disease	Mammary Carcinoma, Human	ABCC1 BCL2 PALB2 STAT3 SLC10A6 BCAR3 MED12	2.61e-03	525	104	7	C4704874
Disease	Mammary Neoplasms, Human	ABCC1 BCL2 PALB2 STAT3 SLC10A6 BCAR3 MED12	2.61e-03	525	104	7	C1257931
Disease	Mammary Neoplasms	ABCC1 BCL2 PALB2 STAT3 SLC10A6 BCAR3 MED12	2.67e-03	527	104	7	C1458155
Disease	Seckel syndrome	ATR PLK4	2.71e-03	22	104	2	C0265202
Disease	Breast Carcinoma	ABCC1 BCL2 PALB2 STAT3 SLC10A6 BCAR3 MED12	2.99e-03	538	104	7	C0678222
Disease	migraine disorder, diastolic blood pressure	SLC24A3 POC5	3.50e-03	25	104	2	EFO_0006336, MONDO_0005277
Disease	Dwarfism	FBXL3 PLK4	3.50e-03	25	104	2	C0013336
Disease	colon adenocarcinoma (is_marker_for)	BCL2 STAT3	3.50e-03	25	104	2	DOID:234 (is_marker_for)
Disease	apolipoprotein L1 measurement	CYP11B1 CYP11B2	3.50e-03	25	104	2	EFO_0021854

Protein segments in the cluster

Peptide	Gene	Start	Entry
PLETFLASLHMEDFA	USH1G	391	Q495M9
FPEMQSLHSAFLTCV	URB2	801	Q14146
ENTFLSIPHMASTLF	ABHD13	216	Q7L211
SVFHHLDLEMLSSPQ	EPC1	476	Q9H2F5
FSFIPSAALDLLDHM	CDK12	986	Q9NYV4
NHQFPLASSMDLLSS	BCAR3	16	O75815
NHELFSKSFISMEVP	ADD3	611	Q9UEY8
HFIIPQMADSSLDLS	GIT2	246	Q14161
FHPMVDSSTSRLEFI	CHI3L2	111	Q15782
GLMVSLSTDDPLQFH	AMPD2	756	Q01433
MSFPASLAAQHFLLE	DEUP1	551	Q05D60
DFLSMTQQDSHAPLR	DHX30	206	Q7L2E3
FLKMESLNFIRAHTP	MS4A1	146	P11836
QMEFLECLFPTDFHS	ATG2B	606	Q96BY7
SLSFPHEKLLLMSTD	ARHGEF39	301	Q8N4T4
FHTPDKLSFILDLMN	GRK2	261	P25098
DLAQKFADTHSMPLF	RAB33B	161	Q9H082
FADTHSMPLFETSAK	RAB33B	166	Q9H082
YHNLFPDSMTATQLL	RBM39	511	Q14498
AHSPSTLLTTLMFFN	QRICH1	616	Q2TAL8
FASPLHSLEMSKNLS	MTCL1	1586	Q9Y4B5
IPHLLLFSFATFNEM	OR5D14	196	Q8NGL3
TMHSLLDDAFALVAP	KIAA1549	1686	Q9HCM3
FPTDTRLNAMLHIDS	HECW2	451	Q9P2P5
IFMYLQPSSSHSLDA	OR8U8	256	P0C7N1
LNTMFFLSPAETHQR	OR8G5	21	Q8NG78
PVMDFFSSHLLADSS	POC5	116	Q8NA72
EQSALFQMPLESFHS	MAP3K10	361	Q02779
SVLRMSFEFHQDPES	MDN1	2661	Q9NU22
ISPLSDHSFDLQTMI	GLI3	296	P10071
TSDMETILTFIPQFH	MMRN1	766	Q13201
SESLLAMFDPLSSHE	GAPVD1	821	Q14C86
LESNHTLRFMSFPVS	CARMIL3	621	Q8ND23
PSLSIFTLMIFDECH	DDX58	361	O95786
IFLDDSIASQPHLTM	CCNYL2	126	Q5T2Q4
SFSSPLLAMAHVDLT	KPTN	361	Q9Y664
PDVVHQSLFMSALSA	L3MBTL1	706	Q9Y468
FATPKMIADFLSAHE	OR4K5	76	Q8NGD3
FDNMSDTELHDLLPF	CTDSP1	226	Q9GZU7
FPDDVPTSLHFQSML	KANSL1	671	Q7Z3B3
FMIDTLENPAAHTFT	MED12	1021	Q93074
ASPGRLHISDFSFLM	PRKCG	341	P05129
SELLSHNTKLTPMEF	MUC5AC	221	P98088
SQFKDADLNSMFLPH	PPP2R3A	61	Q06190
IFMYLQPSSSHALDT	OR8U9	256	P0C7N5
MVDELLSAYPHQLSF	SLC24A3	311	Q9HC58
SLQEFLAALHLMASP	NLRC5	516	Q86WI3
PLLLMSLAFAQEFSS	PANX3	46	Q96QZ0
THRLFPNTMLFASEA	GBA	366	P04062
FLKSMPAEEAHFINT	OBSCN	6721	Q5VST9
DAFTAPFHRDGMLSL	PALB2	586	Q86YC2
FDKQFNDHLMPLISS	EXOC5	496	O00471
FLVESLHSSQMTALP	ATR	936	Q13535
SFMDLPKSHFISALT	FBXL3	151	Q9UKT7
SMLLTDPHLALTVFF	FMO1	451	Q01740
SDLHFLLDFNTVSPM	CCNA1	171	P78396
FLEATDNSHLRSMPA	SQLE	376	Q14534
MTAKLLPSFLHCFSD	HEATR4	726	Q86WZ0
MGNELFLAFTTSHLP	FOXR1	1	Q6PIV2
PSSASLNFLHALEVM	CYP11B1	216	P15538
LEAELPDDFTAHLFM	DGKB	71	Q9Y6T7
MESAAALHFSRPASL	BTN2A1	1	Q7KYR7
RELMDAEFPHSFLVS	FGD2	376	Q7Z6J4
DRILMKATAFSPHFS	INO80D	281	Q53TQ3
KDSLDPSFTHAMQLL	KHDRBS1	111	Q07666
PSSASLNFLHALEVM	CYP11B2	216	P19099
PFHFAQSLMTTERLS	HDAC7	331	Q8WUI4
MDTKHFLPLDFSTQV	RXRA	1	P19793
GTSSLELRFLPFNMH	CFAP47	2081	Q6ZTR5
HFLCDVDPLMALSSA	OR11H7	176	Q8NGC8
DNVIPHFFCDMSALL	OR1E1	171	P30953
DLLHSILRSPMSFFE	ABCC1	1051	P33527
HLSFRMLTFSNNVEP	NAV1	1671	Q8NEY1
IFMYLQPSSSHALDT	OR8U1	256	Q8NH10
PELTSHTMRFNAFIL	RUSC2	1096	Q8N2Y8
LPFTIDTMVDSLLHF	TAAR5	266	O14804
MFRHTDSLFPILLQT	VAC14	436	Q08AM6
VFHKMSPNETLFLES	RRAGC	81	Q9HB90
LFDNIFSNHPSFLLM	TBC1D31	591	Q96DN5
SFSMHNEEPFALLLF	STRIP2	236	Q9ULQ0
HTFLPQIEAALMESS	SYNE3	476	Q6ZMZ3
EDRPMLQFLLHTSFL	TMEM161A	261	Q9NX61
EHLELIGSNFSSAMP	FBXL18	486	Q96ME1
TQAILPMQFHSFDRS	NBEA	1776	Q8NFP9
DHNASMDFADLPALF	RNF167	31	Q9H6Y7
ALSSAIVTMPHFEFR	PREX1	906	Q8TCU6
ASLTLHFERAPFMSQ	TENM2	976	Q9NT68
SSLFPILLHFHIMEA	TEFM	241	Q96QE5
ADRLSLSSVLDHPFM	PLK4	251	O00444
PFAQHSSLDSRIEML	SETD1A	481	O15047
FHPAMEALSLSSLSE	URB1	2191	O60287
FASSRFLQPVHKIDM	SEC23B	226	Q15437
DSAFLLSQVAPSLFM	SLC45A3	496	Q96JT2
SFHVSMDFLEDPSQR	SCN1A	696	P35498
DFAEMSSQLHLTPFT	BCL2	111	P10415
DMIAKAPDFLSTFHI	CIB2	171	O75838
NMILRAPDFLSTFHI	CIB3	171	Q96Q77
IFMARDFATPSLHTS	RNF213	2256	Q63HN8
TFLSDFLLTHRVFMP	RAPGEF3	416	O95398
SLTFDAVALDMLNPH	TRMT61B	326	Q9BVS5
EQLHQLYSDSFPMEL	STAT3	16	P40763
FVPSDFMEELLTLHS	SPATA31D1	371	Q6ZQQ2
FMEELLTLHSSEAFL	SPATA31D1	376	Q6ZQQ2
TAFHLDSDLMLQNPS	TBC1D23	356	Q9NUY8
KMIHELLDPNSSFSV	PIEZO2	2516	Q9H5I5
LSFTAEHLVQMLSFP	SLC10A6	276	Q3KNW5
ALLSFMDFLSSAAPF	VPS13C	1546	Q709C8
MPLALLSAFSHQEAR	PIGZ	376	Q86VD9
VFSQMIAFHDPELSN	TBCK	596	Q8TEA7
MEDLLQACHSTFPDL	ZBTB39	111	O15060
EKPVMLLNHFTSSSA	ZCCHC14	456	Q8WYQ9
AMELLFLDTFKHPSA	VIRMA	6	Q69YN4
SLAMSSHFTQDLLPE	ZNF195	146	O14628
INMFLFSHSPSNRLL	TCIRG1	611	Q13488
SPFFHMAAETLLQQD	KCNJ1	276	P48048
AILKSMDSFSFLQHP	MYO9A	736	B2RTY4
SSSDLLLDFPNSKMH	MYSM1	241	Q5VVJ2