Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	inward rectifier potassium channel activity	KCNJ6 KCNJ10 KCNJ15	1.86e-05	28	37	3	GO:0005242
GeneOntologyMolecularFunction	voltage-gated potassium channel activity	KCNJ6 KCNJ10 KCNJ15	8.86e-04	102	37	3	GO:0005249
GeneOntologyMolecularFunction	potassium channel activity	KCNJ6 KCNJ10 KCNJ15	1.70e-03	128	37	3	GO:0005267
GeneOntologyBiologicalProcess	thioester metabolic process	ELOVL1 MPC1 ACSM4 SLC25A1	4.26e-05	109	37	4	GO:0035383
GeneOntologyBiologicalProcess	acyl-CoA metabolic process	ELOVL1 MPC1 ACSM4 SLC25A1	4.26e-05	109	37	4	GO:0006637
GeneOntologyBiologicalProcess	lipid biosynthetic process	ELOVL1 B3GALNT1 ACSM4 NR3C1 SLC25A1 PI4KA SERPINA12 CYB5R3	7.86e-05	813	37	8	GO:0008610
GeneOntologyBiologicalProcess	thioester biosynthetic process	ELOVL1 MPC1 SLC25A1	9.25e-05	49	37	3	GO:0035384
GeneOntologyBiologicalProcess	acyl-CoA biosynthetic process	ELOVL1 MPC1 SLC25A1	9.25e-05	49	37	3	GO:0071616
GeneOntologyBiologicalProcess	potassium ion import across plasma membrane	KCNJ6 KCNJ10 KCNJ15	1.04e-04	51	37	3	GO:1990573
GeneOntologyBiologicalProcess	purine nucleoside bisphosphate metabolic process	ELOVL1 MPC1 ACSM4 SLC25A1	1.19e-04	142	37	4	GO:0034032
GeneOntologyBiologicalProcess	nucleoside bisphosphate metabolic process	ELOVL1 MPC1 ACSM4 SLC25A1	1.19e-04	142	37	4	GO:0033865
GeneOntologyBiologicalProcess	ribonucleoside bisphosphate metabolic process	ELOVL1 MPC1 ACSM4 SLC25A1	1.19e-04	142	37	4	GO:0033875
GeneOntologyBiologicalProcess	ribonucleoside bisphosphate biosynthetic process	ELOVL1 MPC1 SLC25A1	1.78e-04	61	37	3	GO:0034030
GeneOntologyBiologicalProcess	purine nucleoside bisphosphate biosynthetic process	ELOVL1 MPC1 SLC25A1	1.78e-04	61	37	3	GO:0034033
GeneOntologyBiologicalProcess	nucleoside bisphosphate biosynthetic process	ELOVL1 MPC1 SLC25A1	1.78e-04	61	37	3	GO:0033866
GeneOntologyBiologicalProcess	carboxylic acid transmembrane transport	MPC1 LRRC8B SLC25A1 KCNJ10	2.03e-04	163	37	4	GO:1905039
GeneOntologyBiologicalProcess	organic acid transmembrane transport	MPC1 LRRC8B SLC25A1 KCNJ10	2.22e-04	167	37	4	GO:1903825
HumanPheno	CNS hypomyelination	ELOVL1 MED27 PI4KA KCNJ10 CYB5R3	6.45e-06	99	15	5	HP:0003429
HumanPheno	Abnormal formation of myelin sheaths	ELOVL1 MED27 PI4KA KCNJ10 CYB5R3	1.59e-05	119	15	5	HP:0004335
Domain	K_chnl_inward-rec_Kir_cyto	KCNJ6 KCNJ10 KCNJ15	3.94e-06	16	37	3	IPR013518
Domain	IRK	KCNJ6 KCNJ10 KCNJ15	3.94e-06	16	37	3	PF01007
Domain	-	KCNJ6 KCNJ10 KCNJ15	3.94e-06	16	37	3	2.60.40.1400
Domain	K_chnl_inward-rec_Kir	KCNJ6 KCNJ10 KCNJ15	3.94e-06	16	37	3	IPR016449
Domain	RFX1_trans_act	RFX2 RFX3	1.14e-05	3	37	2	IPR007668
Domain	RFX1_trans_act	RFX2 RFX3	1.14e-05	3	37	2	PF04589
Domain	Ig_E-set	PLXNA4 KCNJ6 KCNJ10 KCNJ15	5.20e-05	104	37	4	IPR014756
Domain	RFX_DNA_binding	RFX2 RFX3	1.36e-04	9	37	2	PF02257
Domain	DNA-bd_RFX	RFX2 RFX3	1.36e-04	9	37	2	IPR003150
Domain	RFX_DBD	RFX2 RFX3	1.36e-04	9	37	2	PS51526
Domain	-	PLXNA4 WSB2 NBEA DMXL1 POC1B	4.77e-04	333	37	5	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	PLXNA4 WSB2 NBEA DMXL1 POC1B	4.90e-04	335	37	5	IPR015943
Domain	WD40	WSB2 NBEA DMXL1 POC1B	1.67e-03	259	37	4	PF00400
Domain	Plexin_repeat	PLXNA4 ATRN	1.82e-03	32	37	2	IPR002165
Domain	PSI	PLXNA4 ATRN	1.82e-03	32	37	2	PF01437
Domain	WD40	WSB2 NBEA DMXL1 POC1B	1.89e-03	268	37	4	SM00320
Domain	WD40_repeat	WSB2 NBEA DMXL1 POC1B	1.99e-03	272	37	4	IPR001680
Domain	WD_REPEATS_1	WSB2 NBEA DMXL1 POC1B	2.16e-03	278	37	4	PS00678
Domain	WD_REPEATS_2	WSB2 NBEA DMXL1 POC1B	2.18e-03	279	37	4	PS50082
Domain	WD_REPEATS_REGION	WSB2 NBEA DMXL1 POC1B	2.18e-03	279	37	4	PS50294
Domain	WD40_repeat_dom	WSB2 NBEA DMXL1 POC1B	2.74e-03	297	37	4	IPR017986
Domain	PSI	PLXNA4 ATRN	3.43e-03	44	37	2	IPR016201
Domain	PSI	PLXNA4 ATRN	3.74e-03	46	37	2	SM00423
Pathway	REACTOME_ACTIVATION_OF_G_PROTEIN_GATED_POTASSIUM_CHANNELS	KCNJ6 KCNJ10 KCNJ15	3.06e-05	30	29	3	MM14542
Pathway	REACTOME_INWARDLY_RECTIFYING_K_CHANNELS	KCNJ6 KCNJ10 KCNJ15	4.90e-05	35	29	3	M1075
Pathway	REACTOME_INWARDLY_RECTIFYING_K_CHANNELS	KCNJ6 KCNJ10 KCNJ15	5.34e-05	36	29	3	MM14544
Pathway	REACTOME_GABA_B_RECEPTOR_ACTIVATION	KCNJ6 KCNJ10 KCNJ15	9.14e-05	43	29	3	M954
Pathway	REACTOME_GABA_B_RECEPTOR_ACTIVATION	KCNJ6 KCNJ10 KCNJ15	9.80e-05	44	29	3	MM15709
Pathway	REACTOME_NEURONAL_SYSTEM	NBEA ACHE SLITRK1 KCNJ6 KCNJ10 KCNJ15	1.59e-04	411	29	6	M735
Pathway	REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES	NBEA ACHE KCNJ6 KCNJ10 KCNJ15	2.02e-04	270	29	5	M15514
Pathway	REACTOME_GABA_RECEPTOR_ACTIVATION	KCNJ6 KCNJ10 KCNJ15	2.48e-04	60	29	3	M976
Pathway	REACTOME_GABA_RECEPTOR_ACTIVATION	KCNJ6 KCNJ10 KCNJ15	2.48e-04	60	29	3	MM15708
Pathway	REACTOME_NEUROTRANSMITTER_RECEPTORS_AND_POSTSYNAPTIC_SIGNAL_TRANSMISSION	NBEA KCNJ6 KCNJ10 KCNJ15	7.76e-04	205	29	4	M752
Pathway	REACTOME_POTASSIUM_CHANNELS	KCNJ6 KCNJ10 KCNJ15	1.04e-03	98	29	3	MM14545
Pathway	REACTOME_POTASSIUM_CHANNELS	KCNJ6 KCNJ10 KCNJ15	1.21e-03	103	29	3	M1073
Pathway	REACTOME_FOXO_MEDIATED_TRANSCRIPTION_OF_OXIDATIVE_STRESS_METABOLIC_AND_NEURONAL_GENES	PLXNA4 NR3C1	1.72e-03	30	29	2	M27941
Pathway	WP_ALSTROM_SYNDROME	RFX2 RFX3	2.20e-03	34	29	2	M45524
Pubmed	International Union of Pharmacology. LIV. Nomenclature and molecular relationships of inwardly rectifying potassium channels.	KCNJ6 KCNJ10 KCNJ15	5.00e-07	15	37	3	16382105
Pubmed	Chromosome 21 KIR channels in brain development.	KCNJ6 KCNJ15	1.10e-06	2	37	2	15068243
Pubmed	Cloning and characterization of two K+ inward rectifier (Kir) 1.1 potassium channel homologs from human kidney (Kir1.2 and Kir1.3).	KCNJ10 KCNJ15	1.10e-06	2	37	2	8995301
Pubmed	Specific localization of an inwardly rectifying K(+) channel, Kir4.1, at the apical membrane of rat gastric parietal cells; its possible involvement in K(+) recycling for the H(+)-K(+)-pump.	KCNJ10 KCNJ15	1.10e-06	2	37	2	11927671
Pubmed	Rare independent mutations in renal salt handling genes contribute to blood pressure variation.	KCNJ6 KCNJ10 KCNJ15	1.68e-06	22	37	3	18391953
Pubmed	Evidence for association of GABA(B) receptors with Kir3 channels and regulators of G protein signalling (RGS4) proteins.	KCNJ6 KCNJ10 KCNJ15	2.51e-06	25	37	3	17185339
Pubmed	Involvement of RFX proteins in transcriptional activation from a Ras-responsive enhancer element.	RFX2 RFX3	3.30e-06	3	37	2	15024578
Pubmed	Kcnj16 (Kir5.1) Gene Ablation Causes Subfertility and Increases the Prevalence of Morphologically Abnormal Spermatozoa.	KCNJ10 KCNJ15	3.30e-06	3	37	2	34205849
Pubmed	Drosophila regulatory factor X is necessary for ciliated sensory neuron differentiation.	RFX2 RFX3	3.30e-06	3	37	2	12403718
Pubmed	RFX1, a transactivator of hepatitis B virus enhancer I, belongs to a novel family of homodimeric and heterodimeric DNA-binding proteins.	RFX2 RFX3	3.30e-06	3	37	2	8289803
Pubmed	Dimeric RFX proteins contribute to the activity and lineage specificity of the interleukin-5 receptor alpha promoter through activation and repression domains.	RFX2 RFX3	3.30e-06	3	37	2	10330134
Pubmed	Ciliogenic RFX transcription factors regulate FGF1 gene promoter.	RFX2 RFX3	3.30e-06	3	37	2	22415835
Pubmed	Interplay of RFX transcription factors 1, 2 and 3 in motile ciliogenesis.	RFX2 RFX3	3.30e-06	3	37	2	32725242
Pubmed	Interaction of the Ca2+-sensing receptor with the inwardly rectifying potassium channels Kir4.1 and Kir4.2 results in inhibition of channel function.	KCNJ10 KCNJ15	3.30e-06	3	37	2	17122384
Pubmed	Human regulatory factor X 4 (RFX4) is a testis-specific dimeric DNA-binding protein that cooperates with other human RFX members.	RFX2 RFX3	6.60e-06	4	37	2	11682486
Pubmed	Role of Angiotensin II Type 1a Receptor (AT1aR) of Renal Tubules in Regulating Inwardly Rectifying Potassium Channels 4.2 (Kir4.2), Kir4.1, and Epithelial Na+ Channel (ENaC).	KCNJ10 KCNJ15	6.60e-06	4	37	2	37909221
Pubmed	Copy number variation in ACHE/EPHB4 (7q22) and in BCHE/MME (3q26) genes in sporadic breast cancer.	MME ACHE	6.60e-06	4	37	2	23063927
Pubmed	Co-expression of human Kir3 subunits can yield channels with different functional properties.	KCNJ6 KCNJ10	6.60e-06	4	37	2	10659995
Pubmed	Differential expression of Rfx1-4 during mouse spermatogenesis.	RFX2 RFX3	6.60e-06	4	37	2	19596083
Pubmed	The neurobeachin gene (Nbea) identifies a new region of homology between mouse central chromosome 3 and human chromosome 13q13.	NBEA MME	6.60e-06	4	37	2	10501977
Pubmed	Gene identification in 1.6-Mb region of the Down syndrome region on chromosome 21.	KCNJ6 KCNJ15	6.60e-06	4	37	2	9037601
Pubmed	RFX2 is essential in the ciliated organ of asymmetry and an RFX2 transgene identifies a population of ciliated cells sufficient for fluid flow.	RFX2 RFX3	2.30e-05	7	37	2	22233545
Pubmed	G-protein pathway suppressor 2 (GPS2) interacts with the regulatory factor X4 variant 3 (RFX4_v3) and functions as a transcriptional co-activator.	RFX2 RFX3	6.02e-05	11	37	2	18218630
Pubmed	CIPP, a novel multivalent PDZ domain protein, selectively interacts with Kir4.0 family members, NMDA receptor subunits, neurexins, and neuroligins.	KCNJ10 KCNJ15	6.02e-05	11	37	2	9647694
Pubmed	Global gene expression analysis in fetal mouse ovaries with and without meiosis and comparison of selected genes with meiosis in the testis.	B3GALNT1 NR3C1	8.53e-05	13	37	2	17431699
Pubmed	Platelet storage pool deficiency associated with inherited abnormalities of the inner ear in the mouse pigment mutants muted and mocha.	ATRN KCNJ6	9.94e-05	14	37	2	1912584
Pubmed	Neuronal interleukin-16 (NIL-16): a dual function PDZ domain protein.	KCNJ10 KCNJ15	1.15e-04	15	37	2	10479680
Pubmed	Physical and comparative mapping of distal mouse chromosome 16. 5 p5.	KCNJ6 KCNJ15	1.31e-04	16	37	2	9750193
Pubmed	Transcription factor TAp73 and microRNA-449 complement each other to support multiciliogenesis.	RFX2 RFX3	1.48e-04	17	37	2	31068677
Pubmed	Analysis of mice carrying targeted mutations of the glucocorticoid receptor gene argues against an essential role of glucocorticoid signalling for generating adrenal chromaffin cells.	NR3C1 ACHE	1.48e-04	17	37	2	10357937
Pubmed	miRNA 34a, 100, and 137 modulate differentiation of mouse embryonic stem cells.	MPC1 RIF1 RNMT RFX2	1.86e-04	268	37	4	20439489
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	RIF1 NR3C1 RFX2 RFX3 BRPF1 PHTF1	1.94e-04	808	37	6	20412781
Pubmed	Rfx6 directs islet formation and insulin production in mice and humans.	RFX2 RFX3	2.28e-04	21	37	2	20148032
Pubmed	The Rfx4 transcription factor modulates Shh signaling by regional control of ciliogenesis.	RFX2 RFX3	2.51e-04	22	37	2	19887680
Pubmed	PlexinA1 signaling directs the segregation of proprioceptive sensory axons in the developing spinal cord.	PLXNA4 ATRN SLITRK1	2.65e-04	117	37	3	17145500
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	RIF1 NR3C1 RFX2 RFX3 PI4KA HERC5	2.66e-04	857	37	6	25609649
Pubmed	Hepatic Glucocorticoid Receptor Plays a Greater Role Than Adipose GR in Metabolic Syndrome Despite Renal Compensation.	MPC1 NR3C1	2.99e-04	24	37	2	27754788
Pubmed	SOX9 and SOX10 control fluid homeostasis in the inner ear for hearing through independent and cooperative mechanisms.	MME KCNJ10	3.80e-04	27	37	2	36343245
Pubmed	Morphology-based mammalian stem cell tests reveal potential developmental toxicity of donepezil.	ELOVL1 ACHE	3.80e-04	27	37	2	25269881
Pubmed	Role of the E3 ubiquitin ligase RNF157 as a novel downstream effector linking PI3K and MAPK signaling pathways to the cell cycle.	ATRN SLC25A1	4.09e-04	28	37	2	28655764
Pubmed	Biosynthesis of triacylglycerols.	ELOVL1 SLC25A1	4.09e-04	28	37	2	8944226
Pubmed	Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.	KCNJ6 KCNJ10 KCNJ15	4.39e-04	139	37	3	16985003
Pubmed	Use of comparative physical and sequence mapping to annotate mouse chromosome 16 and human chromosome 21.	KCNJ6 KCNJ15	4.70e-04	30	37	2	11374901
Pubmed	TBX1 is required for normal stria vascularis and semicircular canal development.	ATRN KCNJ10	5.02e-04	31	37	2	31550482
Pubmed	Genome-wide association study of lung function decline in adults with and without asthma.	PLXNA4 HERC5	5.35e-04	32	37	2	22424883
Pubmed	The ciliogenic transcription factor Rfx3 is required for the formation of the thalamocortical tract by regulating the patterning of prethalamus and ventral telencephalon.	PLXNA4 RFX3	6.05e-04	34	37	2	25631876
Pubmed	HIV gp120 induced gene expression signatures in vaginal epithelial cells.	MME IL18R1	6.41e-04	35	37	2	23867815
Pubmed	Cell cycle-related kinase is a crucial regulator for ciliogenesis and Hedgehog signaling in embryonic mouse lung development.	RFX2 RFX3	8.37e-04	40	37	2	32317081
Pubmed	Novel Cul3 binding proteins function to remodel E3 ligase complexes.	LRRC8B POC1B	8.37e-04	40	37	2	25011449
Pubmed	Lsd1 Ablation Triggers Metabolic Reprogramming of Brown Adipose Tissue.	ELOVL1 MPC1	8.37e-04	40	37	2	27760309
Pubmed	Proteomic analysis of the mouse liver mitochondrial inner membrane.	MPC1 SLC25A1 CYB5R3	8.58e-04	175	37	3	12865426
GeneFamily	Potassium voltage-gated channel subfamily J	KCNJ6 KCNJ10 KCNJ15	9.96e-07	16	23	3	276
GeneFamily	Regulatory factor X family	RFX2 RFX3	4.31e-05	8	23	2	1153
GeneFamily	WD repeat domain containing	WSB2 NBEA DMXL1 POC1B	3.07e-04	262	23	4	362
GeneFamily	Glycosyltransferase family 6\|Blood group antigens	B3GALNT1 ACHE	1.00e-03	37	23	2	454
ToppCell	metastatic_Brain-B_lymphocytes-GrB-secreting_B_cells\|B_lymphocytes / Location, Cell class and cell subclass	PLXNA4 NBEA NR3C1 IL18R1	1.38e-05	177	37	4	43e1d0d3cf8f0c02e67d91f8dd1761df23d59e07
ToppCell	MS-CD8-CD4_Treg\|MS / Condition, Cell_class and T cell subcluster	TBC1D19 MPC1 WSB2 TMEM104	1.75e-05	188	37	4	2f0e2c7d79ee2d69a5d908c0247dc950c056c30a
ToppCell	368C-Myeloid-Macrophage-FABP4+_Macrophage_3\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	MPC1 MME ADTRP CYB5R3	1.90e-05	192	37	4	e1deb743b1f39b58a46b8df134e79d512a000273
ToppCell	COVID-19-Myeloid-TRAM2\|COVID-19 / Condition, Lineage and Cell class	MME ADTRP HERC5 CYB5R3	1.98e-05	194	37	4	c5bdf2b58c10dcb09797ddaf46b2e6c80d10399f
ToppCell	COVID-19-Myeloid-TRAM2\|Myeloid / Condition, Lineage and Cell class	MME ADTRP HERC5 CYB5R3	1.98e-05	194	37	4	4060a60c0271e7397b07993a1ef47b3291bba6e3
ToppCell	367C-Myeloid-Macrophage-FABP4+_Macrophage\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	MPC1 MME ADTRP CYB5R3	2.02e-05	195	37	4	f664fe18856065baaa2837fc82ea946e45f6fcc3
ToppCell	368C-Myeloid-Macrophage-FABP4+_Macrophage_3\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	MPC1 MME ADTRP CYB5R3	2.06e-05	196	37	4	1311d5fbbead32fcc6e6b41133a84f92f461b3d9
ToppCell	mild-Myeloid-Neutrophils_2\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	MME IL18R1 HERC5 KCNJ15	2.06e-05	196	37	4	ded44b38ea489946e9eedfe752b5a9fde9149c16
ToppCell	mild-Myeloid-Neutrophils_2\|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	MME IL18R1 HERC5 KCNJ15	2.06e-05	196	37	4	e9f30eb8a3915c3b2af009c832bff9b349b65ae5
ToppCell	367C-Myeloid-Macrophage-FABP4+_Macrophage\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	MPC1 MME ADTRP CYB5R3	2.10e-05	197	37	4	07aee25e17dbb71e49f7da9fd9ed2537f4a72d82
ToppCell	3'-GW_trimst-1-SmallIntestine-Neuronal-neurons_B-Branch_B2_(eMN)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PLXNA4 NBEA ACHE KCNJ6	2.14e-05	198	37	4	85881637641d8996be2edc65c4bceff0433135e7
ToppCell	10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-Reg_T-Z\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NR3C1 ADTRP IL18R1 HERC5	2.14e-05	198	37	4	d021d0edb6aba2f15c51a3ec4e08c7233d0c1962
ToppCell	MS-IIF-Lymphocyte-T/NK-NK_CD56bright\|IIF / Disease, condition lineage and cell class	PLXNA4 B3GALNT1 IL18R1 PHTF1	2.19e-05	199	37	4	9eb2b7d4900b118338590db778a47504559e228d
ToppCell	Sepsis-Leuk-UTI-Myeloid-tDC\|Leuk-UTI / Disease, condition lineage and cell class	PLXNA4 B3GALNT1 RFX3 IL18R1	2.19e-05	199	37	4	a2f154b15087803958a656d2a41b6d83fd37b32f
ToppCell	PBMC-Mild-cDC_3\|Mild / Compartment, Disease Groups and Clusters	WSB2 MME KCNJ10	3.02e-04	158	37	3	5fefab4831687cd8dd45f5cc84f681398069c3be
ToppCell	Leuk-UTI-Myeloid-tDC\|Leuk-UTI / Disease, Lineage and Cell Type	PLXNA4 B3GALNT1 RFX3	3.20e-04	161	37	3	51b9f60986ed2e8e2297d31c80462c3ab65a2e5e
ToppCell	Influenza_Severe-Neutrophil\|Influenza_Severe / Disease group and Cell class	MME IL18R1 KCNJ15	3.20e-04	161	37	3	98c95b1b85d5427415af2ca8fb14849e97f6e8b5
ToppCell	tumor_Lymph_Node_/_Brain-T/NK_cells-Exhausted_Tfh\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	NR3C1 ADTRP KCNJ15	3.49e-04	166	37	3	c73fce59256ad501864f44f76cfae2fc33b3777e
ToppCell	LV-11._Adipocyte\|World / Chamber and Cluster_Paper	PLXNA4 LRRC8B MME	3.49e-04	166	37	3	7e5852891714465c6228c9f955fd511ec79d0e02
ToppCell	tumor_Lymph_Node_/_Brain-T/NK_cells-CD8+/CD4+_Mixed_Th\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	NR3C1 IL18R1 PHTF1	3.56e-04	167	37	3	c0c944eae0514dc8e00d0c2892a0792e157695ec
ToppCell	PND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RIF1 SLC25A1 KCNJ15	3.62e-04	168	37	3	08f6e171a1ea5cf65149744296d0fcd6c7b9684e
ToppCell	Influenza_Severe-Neutrophil\|World / Disease group and Cell class	MME IL18R1 KCNJ15	3.68e-04	169	37	3	6e8e2580e19c96bcf7fa6a6d8c183df65f428396
ToppCell	facs-Marrow-T_cells-18m-Hematologic-MPP_Fraction_B_+_C\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC8B RFX2 SERPINA12	3.68e-04	169	37	3	2a35846b0e0be0a19a5a04a86cbd72ce65257c8a
ToppCell	facs-Liver-Non-hepatocytes-3m-Epithelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC25A1 SERPINA12 CYB5R3	3.88e-04	172	37	3	feaaf8ca7983d04a59ed0a7b3fb0e6d4b3a055f2
ToppCell	facs-Liver-Non-hepatocytes-3m-Epithelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC25A1 SERPINA12 CYB5R3	3.88e-04	172	37	3	9adfb4a65669cc536343616637058d0a4728013f
ToppCell	facs-Liver-Non-hepatocytes-3m-Epithelial-hepatocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC25A1 SERPINA12 CYB5R3	3.88e-04	172	37	3	8aed9c113f27d00401c272a3684495a4bc75bd0f
ToppCell	droplet-Lung-nan-21m-Myeloid-lung_macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLXNA4 B3GALNT1 KCNJ10	3.94e-04	173	37	3	1cff815536f620e32b9805666e1aa711462c2d25
ToppCell	Mild/Remission-B_naive-8\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	MME RNMT CCDC191	3.94e-04	173	37	3	694d02c4d2dc2de4b344544f9124fec40fcf7d8f
ToppCell	COVID-19_Moderate-NK_CD56bright\|COVID-19_Moderate / disease group, cell group and cell class	PLXNA4 B3GALNT1 IL18R1	3.94e-04	173	37	3	a07dcb1e555caaa2235aec219334fcbf2d07f10c
ToppCell	droplet-Lung-nan-21m-Myeloid-Interstitial_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLXNA4 B3GALNT1 KCNJ10	3.94e-04	173	37	3	31ea04e65876c42b90245d280f0b6439bfffbace
ToppCell	severe_influenza-Neutrophil\|severe_influenza / disease group, cell group and cell class (v2)	MME IL18R1 KCNJ15	3.94e-04	173	37	3	615e266419b9f06e964eff73cb466f05451ba0dd
ToppCell	CF-Myeloid-Neutrophil\|Myeloid / Disease state, Lineage and Cell class	MME IL18R1 KCNJ15	4.08e-04	175	37	3	8020c3a34f77e68e8149f87481fb1dddd2ac675e
ToppCell	343B-Myeloid-Dendritic-pDC\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	PLXNA4 NR3C1 RFX3	4.08e-04	175	37	3	b30589ff9dc18e745afe61f289e6d576c9c6c6b2
ToppCell	metastatic_Brain-T/NK_cells-Exhausted_Tfh\|metastatic_Brain / Location, Cell class and cell subclass	NR3C1 BRPF1 PHTF1	4.08e-04	175	37	3	b732c6a423c28856211002107d8c611dcfb6f265
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Plasmacytoid_Dendritic_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PLXNA4 IL18R1 BRPF1	4.15e-04	176	37	3	8488997e0f02e874f53fae1690da63e0dd1d0780
ToppCell	COVID-19_Mild-NK_CD56bright\|COVID-19_Mild / Disease condition and Cell class	PLXNA4 B3GALNT1 IL18R1	4.36e-04	179	37	3	90e7a4af195aa2332b07a9f06cde63e72ff49255
ToppCell	COVID-19_Severe-Neutrophil-\|COVID-19_Severe / Disease condition and Cell class	MME IL18R1 KCNJ15	4.50e-04	181	37	3	5e5101195d5ff8c8ea7ddcf0bc4f4e03e64c01e0
ToppCell	COVID-19_Severe-Neutrophil\|COVID-19_Severe / Disease condition and Cell class	MME IL18R1 KCNJ15	4.50e-04	181	37	3	aa5e5fb0308b5e2ef918548c85529c9a433c57f5
ToppCell	droplet-Liver-Npc-21m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NBEA ACHE KCNJ15	4.57e-04	182	37	3	dc55de945c6f78f32eb3a1b3520835eb8417e068
ToppCell	droplet-Liver-Npc-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NBEA ACHE KCNJ15	4.57e-04	182	37	3	010a7364da46101cb5068891fd7bc712ea8f13bd
ToppCell	cellseq2-Immune-Hematopoietic-Granulocytic-Neutrophil\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MME IL18R1 KCNJ15	4.57e-04	182	37	3	1932d77491d6d46278f01fd70eb469ef1b356619
ToppCell	cellseq2-Immune-Hematopoietic-Granulocytic\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MME IL18R1 KCNJ15	4.65e-04	183	37	3	cfbf8539104cef9ca830ad4f6bb278746f7078f7
ToppCell	mild_COVID-19-NK_CD56bright\|World / disease group, cell group and cell class (v2)	PLXNA4 B3GALNT1 IL18R1	4.65e-04	183	37	3	9a4899afac0f91203209392c5f67b3d0aa356b86
ToppCell	cellseq2-Immune-Hematopoietic\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MME IL18R1 KCNJ15	4.65e-04	183	37	3	324ec4374b552da7ce03809945b3a0798342d4ba
ToppCell	Calu_3-infected\|Calu_3 / Cell line, Condition and Strain	RIF1 NR3C1 HERC5	4.65e-04	183	37	3	8f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCell	B_cells-ISG-high_B_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	RFX3 HERC5 DMXL1	4.65e-04	183	37	3	dc2b00e920efa1dcc2a6265cd1024e3249c9974f
ToppCell	COVID-19_Mild-Lymphoid_T/NK-NK_CD56bright\|COVID-19_Mild / Disease group, lineage and cell class	PLXNA4 B3GALNT1 IL18R1	4.72e-04	184	37	3	f67308228bb6a5d624279fbb04db25a2f4087c9b
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_CD56bright-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	PLXNA4 B3GALNT1 IL18R1	4.79e-04	185	37	3	3a046c948524e5d0e986cd645e318d6930d7e0ee
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_CD56bright\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	PLXNA4 B3GALNT1 IL18R1	4.79e-04	185	37	3	71d1a771026d9fa3528d46ac3d11353e396f2d87
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_CD56bright\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PLXNA4 B3GALNT1 IL18R1	4.79e-04	185	37	3	df5d2309d19ac8d5e429afa785d0a480e75a8f9e
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_CD56bright-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PLXNA4 B3GALNT1 IL18R1	4.79e-04	185	37	3	37b48218dd523049b57b13eb9cdb34e106cf91ea
ToppCell	droplet-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MME KCNJ6 KCNJ15	4.87e-04	186	37	3	4e983de6d2515082f9e555f4f949cec84281c140
ToppCell	facs-Lung-EPCAM-3m\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MME IL18R1 KCNJ15	4.87e-04	186	37	3	7c4eb769574f9f32753cea1cc38c711dabba88b9
ToppCell	Influenza-Influenza_Severe-Myeloid-Neutrophil\|Influenza_Severe / Disease, condition lineage and cell class	MME IL18R1 KCNJ15	4.87e-04	186	37	3	1dfcec9196d4db76fba3abc74e85885b1fb98b87
ToppCell	normal_Lymph_Node-B_lymphocytes-GC_B_cells_in_the_LZ\|B_lymphocytes / Location, Cell class and cell subclass	B3GALNT1 MME CYB5R3	4.95e-04	187	37	3	457eb3791a8c5458d81833e0701ac5a9bfdee2bf
ToppCell	RA-11._Adipocyte\|World / Chamber and Cluster_Paper	PLXNA4 LRRC8B MME	5.02e-04	188	37	3	4dac9d636e5cad4cda540b93d4bfed6b5732c880
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_granulocytic-neutrophil\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	MME IL18R1 KCNJ15	5.26e-04	191	37	3	b9b091d6b352d5128bb864ff52d2e5fb3387b766
ToppCell	PND28-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ELOVL1 MME KCNJ15	5.34e-04	192	37	3	7ccdb977320d09f21e70e7718ead73eeb56d0c48
ToppCell	PND28-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ELOVL1 MME KCNJ15	5.34e-04	192	37	3	f206c015f091234e2c86dfa66926e97b2ea99690
ToppCell	PND28-Epithelial-Epithelial_Alveolar\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ELOVL1 MME KCNJ15	5.34e-04	192	37	3	69963e8dc6d6368243e61da133484eb23225625a
ToppCell	PND28-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ELOVL1 MME KCNJ15	5.34e-04	192	37	3	bfc68af68fdb99ddfe4add49671e4b4c26e6f962
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_granulocytic\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	MME IL18R1 KCNJ15	5.34e-04	192	37	3	3ce486cd5171f2d04ac4f7f87bead8b0d8c99c17
ToppCell	15-Trachea-Epithelial-Intermediate_ciliated\|Trachea / Age, Tissue, Lineage and Cell class	NBEA RFX2 RFX3	5.34e-04	192	37	3	9cbe961a800c981cdc742a47ed18e9c8eb6430bd
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child\|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)	ACSM4 RNMT CCDC191	5.34e-04	192	37	3	aee6522d25e012231cdb905ce047295cb64d6e82
ToppCell	facs-Trachea-3m-Epithelial-glandular_epithelial-lung_secretory_cell-mucous\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADTRP IL18R1 KCNJ15	5.42e-04	193	37	3	c5925b3b5d19098e3987789d68a493d7fd548ac9
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage_2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	MME ADTRP CYB5R3	5.42e-04	193	37	3	aa679fb27f914a931e51cff7153861cde0edfd85
ToppCell	facs-Trachea-3m-Epithelial-glandular_epithelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADTRP IL18R1 KCNJ15	5.42e-04	193	37	3	6905de261d90dfe3dd2c2cf5b2e26afb2bcc3d5b
ToppCell	Control-NK_CD56bright\|Control / Disease condition and Cell class	PLXNA4 B3GALNT1 IL18R1	5.42e-04	193	37	3	8b1e7a226a6057e1097c1525984127b54e823876
ToppCell	facs-Trachea-3m-Epithelial-glandular_epithelial-lung_secretory_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADTRP IL18R1 KCNJ15	5.42e-04	193	37	3	f73630725f093c646bdaf178c39505c04a16e2c6
ToppCell	control-Myeloid-Neutrophils_3\|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	MME IL18R1 KCNJ15	5.42e-04	193	37	3	56daf3c59a124dd068af5409113913d9ee81a454
ToppCell	COVID_vent-Myeloid-Monocytic-Neutrophil\|COVID_vent / Disease condition, Lineage, Cell class and subclass	MME HERC5 KCNJ15	5.51e-04	194	37	3	eb23b171e429165dd26a64377eae7fa2ce25f547
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NBEA RFX3 CCDC191	5.51e-04	194	37	3	4a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCell	control-Myeloid-Neutrophils_3\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	MME IL18R1 KCNJ15	5.51e-04	194	37	3	2218e6677dc6781a6e4ef3a315f2298cc2cd9df2
ToppCell	B_cells-ISG-high_B_cells\|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis	RFX3 HERC5 DMXL1	5.59e-04	195	37	3	b64d9e1a8834401b4dc501566546647754ae21fc
ToppCell	droplet-Trachea-3m-Epithelial-airway_epithelial-epithelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADTRP IL18R1 KCNJ15	5.59e-04	195	37	3	4d7ca21f14730e1b6d0473bc1a11aa626db948f3
ToppCell	droplet-Trachea-3m-Epithelial-airway_epithelial-epithelial_cell-epithelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADTRP IL18R1 KCNJ15	5.59e-04	195	37	3	8727554ef047ca7f1d4b888a8468f148c64a6918
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NBEA RFX3 CCDC191	5.59e-04	195	37	3	9651ee03738226ee10e901f8b9ec6a417eb9c301
ToppCell	droplet-Trachea-nan-3m-Epithelial-epithelial_cell\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADTRP IL18R1 KCNJ15	5.59e-04	195	37	3	9f0ee826d4f0997aee8d63284ed24549bbdf6a28
ToppCell	Mild/Remission-B_naive-8\|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)	MME RNMT CCDC191	5.59e-04	195	37	3	0a3221e4d1fa31a35868bdda0f0cc873c233b407
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage_2\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	MME ADTRP CYB5R3	5.67e-04	196	37	3	fe90501010128b72e6711c567cb04b012f1520a4
ToppCell	Control\|World / Condition, Lineage and Cell class	MME ADTRP CYB5R3	5.67e-04	196	37	3	2565f567c5274d1689e11600a2cb9e6770b65f74
ToppCell	Control-B_naive-8\|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)	MME RNMT CCDC191	5.67e-04	196	37	3	54074da84000e4749ade8acc542f05a275bf829f
ToppCell	distal-Endothelial-Bronchial_Vessel_2-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	NBEA ACHE HERC5	5.76e-04	197	37	3	9fcfbfbe78e8fe90c76eb37a58ed9dc8ece652a1
ToppCell	critical-Myeloid-Neutrophil\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	MME IL18R1 KCNJ15	5.76e-04	197	37	3	f1248781e71e3a158d06e9ec93eb90dc6d48bcb2
ToppCell	10x_3'_v3-lymph_node_(10x_3'_v3)-lymphocytic-T_lymphocytic-type_I_NK_T_cell\|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	NR3C1 IL18R1 HERC5	5.76e-04	197	37	3	51340570667914bffec741c72a8d09cc46abb8e8
ToppCell	10x_3'_v3-lymph_node_(10x_3'_v3)-lymphocytic-T_lymphocytic-T_cell\|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	NR3C1 IL18R1 HERC5	5.76e-04	197	37	3	076fc05b32200e0a8a1e35d03c295111468d92a9
ToppCell	Bronchus_Control_(B.)-Immune-TX-TRAM-2\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	MME ADTRP HERC5	5.76e-04	197	37	3	eecb693367510da20a6b1e9355e68785a1e3b85c
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATRN LRRC8B KCNJ10	5.84e-04	198	37	3	a7e5de81eb7d3d23812c179a001adbaab1506596
ToppCell	TCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma\|TCGA-Bladder / Sample_Type by Project: Shred V9	TMEM104 MED27 SURF4	5.84e-04	198	37	3	65875fbd99393cdd62595c713ab90db06d28081f
ToppCell	390C-Myeloid-Macrophage-FABP4+_Macrophage_2\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	MPC1 MME ADTRP	5.84e-04	198	37	3	8a4b4bb6839b9ec52ff0b9c7b39cec8d9a9525bd
ToppCell	10x_3'_v3-spleen_(10x_3'_v3)-myeloid-myeloid_granulocytic\|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	MME IL18R1 KCNJ15	5.93e-04	199	37	3	119807ea333d1dc7743c6b9f03a2c63e09e19541
ToppCell	10x_3'_v3-spleen_(10x_3'_v3)-myeloid-myeloid_granulocytic-neutrophil\|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	MME IL18R1 KCNJ15	5.93e-04	199	37	3	691e04871cd6cac0ea5fca1b7fd6421df9315db6
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-Mesenchymal-Unfolded_protein_responsible_cell\|10w / Sample Type, Dataset, Time_group, and Cell type.	MPC1 ACHE SURF4	6.01e-04	200	37	3	bc479baca21f0ff19a1c4efdb9530f289a1ab115
ToppCell	mild-NK_CD56bright\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	PLXNA4 B3GALNT1 IL18R1	6.01e-04	200	37	3	a195bc6784346f706d4cd5b740adac1d950ce88a
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-1m-Macroglial-Glia_progenitor_cell\|1m / Sample Type, Dataset, Time_group, and Cell type.	MPC1 SURF4 HERC5	6.01e-04	200	37	3	26940eee4a2f2aafd857964b5607e7dfb65f8d6f
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-Mesenchymal\|10w / Sample Type, Dataset, Time_group, and Cell type.	MPC1 ACHE SURF4	6.01e-04	200	37	3	c968d077b7fd24fb06cedb51c737996f25667eb7
ToppCell	Control_saline-Endothelial-Endothelial-Activated_Alv_Cap\|Control_saline / Treatment groups by lineage, cell group, cell type	NR3C1 HERC5 CYB5R3	6.01e-04	200	37	3	be55cef682ba87250dad97689332c8820b3a7420
ToppCell	mild-NK_CD56bright\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	PLXNA4 B3GALNT1 IL18R1	6.01e-04	200	37	3	6de701985a0b92a7dece1b0e4a76e13756ccc0dd
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_CD56bright\|COVID-19_Mild / Disease, condition lineage and cell class	PLXNA4 B3GALNT1 IL18R1	6.01e-04	200	37	3	bb21e26a8b7cbceddb1ab5163a223a186d914da4
ToppCell	10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_granulocytic-neutrophil\|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	MME IL18R1 KCNJ15	6.01e-04	200	37	3	6beabd5bad042d4d65c89c2f537c7376230f7c08
Drug	AC1NSUFP	NR3C1 ACHE	2.57e-06	2	37	2	CID005316604
Drug	rubidium	RIF1 KCNJ6 KCNJ10 KCNJ15	2.88e-06	61	37	4	CID000105153
Drug	1 sulfonylurea	ATRN SLC25A1 KCNJ6 KCNJ10 KCNJ15	3.38e-06	143	37	5	CID011819083
Drug	fenchone	NR3C1 ACHE	7.70e-06	3	37	2	ctd:C027327
Drug	cyolane	MME ACHE	7.70e-06	3	37	2	CID000013689
Drug	pararosaniline	NR3C1 ACHE	1.54e-05	4	37	2	ctd:C005409
Drug	thiodicarb	MME ACHE	2.56e-05	5	37	2	CID000062155
Drug	desbromoleptophos	MME ACHE	2.56e-05	5	37	2	CID000040785
Drug	agritox	MME ACHE	3.84e-05	6	37	2	CID000009477
Drug	barium chloride dihydrate	KCNJ6 KCNJ10 KCNJ15	4.66e-05	43	37	3	CID000025157
Drug	sulprofos	MME ACHE	5.37e-05	7	37	2	CID000037125
Drug	azinphos-ethyl	MME ACHE	5.37e-05	7	37	2	CID000017531
Drug	merphos	MME ACHE	5.37e-05	7	37	2	CID000009011
Drug	EPN oxon	MME ACHE	5.37e-05	7	37	2	CID000107973
Drug	fenitrooxon	MME ACHE	7.15e-05	8	37	2	CID000016738
Drug	D-box	NR3C1 ACHE	7.15e-05	8	37	2	CID000133881
Drug	des-CIC	NR3C1 ACHE	9.18e-05	9	37	2	CID006918281
Drug	Leu-thiorphan	MME ACHE	9.18e-05	9	37	2	CID000133576
Drug	isoxathion	MME ACHE	9.18e-05	9	37	2	CID000029307
Drug	BaCl2	KCNJ6 KCNJ10 KCNJ15	9.26e-05	54	37	3	CID000025204
Drug	CID5255110	KCNJ6 KCNJ10 KCNJ15	1.09e-04	57	37	3	CID005255110
Drug	A13108	KCNJ6 KCNJ15	1.15e-04	10	37	2	CID000062278
Drug	phenthoate	MME ACHE	1.15e-04	10	37	2	CID000017435
Drug	cyanofenphos	MME ACHE	1.15e-04	10	37	2	CID000025669
Drug	Rabon	MME ACHE	1.15e-04	10	37	2	CID000013745
Drug	tributyl phosphate	NR3C1 ACHE	1.40e-04	11	37	2	ctd:C009524
Drug	coumaphos	MME ACHE	1.68e-04	12	37	2	CID000002871
Drug	Neuromedin L.	MME NR3C1 ACHE	1.92e-04	69	37	3	CID000055582
Drug	demeton-S	MME ACHE	1.98e-04	13	37	2	CID000024723
Drug	Barium	KCNJ6 KCNJ10 KCNJ15	2.18e-04	72	37	3	ctd:D001464
Drug	leptophos-oxon	MME ACHE	2.31e-04	14	37	2	CID000032765
Drug	methidathion	MME ACHE	2.31e-04	14	37	2	CID000013709
Drug	A-17	MME NR3C1	2.66e-04	15	37	2	CID000171155
Drug	ethion	MME ACHE	2.66e-04	15	37	2	CID000003286
Drug	Pentamidine isethionate [140-64-7]; Down 200; 6.8uM; MCF7; HT_HG-U133A	LRRC8B RNMT NR3C1 HERC5	2.76e-04	195	37	4	4396_DN
Drug	Sulpiride [15676-16-1]; Down 200; 11.8uM; HL60; HG-U133A	ATRN TMEM104 HERC5 PHTF1	2.82e-04	196	37	4	1967_DN
Drug	Baclofen (R,S) [1134-47-0]; Up 200; 18.8uM; MCF7; HT_HG-U133A	TBC1D19 ATRN NR3C1 ADTRP	2.82e-04	196	37	4	1536_UP
Drug	Flecainide acetate [54143-56-5]; Down 200; 8.4uM; MCF7; HT_HG-U133A	TBC1D19 TMEM104 NR3C1 HERC5	2.93e-04	198	37	4	3843_DN
Drug	CP-690334-01 [459212-38-5]; Up 200; 1uM; MCF7; HT_HG-U133A	RIF1 LRRC8B RFX3 KCNJ15	2.93e-04	198	37	4	3909_UP
Drug	Diflunisal [22494-42-4]; Down 200; 16uM; PC3; HG-U133A	B3GALNT1 RIF1 HERC5 PHTF1	2.93e-04	198	37	4	1908_DN
Drug	Pivmecillinam hydrochloride [32887-03-9]; Down 200; 8.4uM; MCF7; HT_HG-U133A	RIF1 TMEM104 NR3C1 ADTRP	2.98e-04	199	37	4	3535_DN
Drug	Ozagrel hydrochloride [78712-43-3]; Down 200; 15.2uM; PC3; HT_HG-U133A	RNMT PI4KA DMXL1 PHTF1	2.98e-04	199	37	4	7281_DN
Drug	FB_5	NR3C1 ACHE	3.04e-04	16	37	2	CID005317329
Drug	hex-2-ene	ACHE KCNJ6	3.04e-04	16	37	2	CID000019966
Drug	Amrinone [60719-84-8]; Down 200; 21.4uM; MCF7; HT_HG-U133A	TBC1D19 ATRN TMEM104 NR3C1	3.04e-04	200	37	4	3465_DN
Drug	phenylalanine	RIF1 MME ACHE PHTF1	3.53e-04	208	37	4	CID000000994
Drug	pinacidil	KCNJ6 KCNJ10 KCNJ15	3.81e-04	87	37	3	CID000004826
Drug	tripitramine	ACHE KCNJ6	3.87e-04	18	37	2	CID000132947
Drug	cromakalim	KCNJ6 KCNJ10 KCNJ15	3.94e-04	88	37	3	CID000071191
Drug	diazoxide	ATRN KCNJ6 KCNJ10 KCNJ15	4.91e-04	227	37	4	CID000003019
Drug	CR-39	NR3C1 SLC25A1	5.29e-04	21	37	2	CID000008879
Drug	tetraethylammonium	ACHE KCNJ6 KCNJ10 KCNJ15	5.68e-04	236	37	4	CID000005413
Drug	methanethiosulfonate	SLC25A1 KCNJ6 KCNJ15	6.25e-04	103	37	3	CID004188587
Drug	Isoflurophate	NR3C1 ACHE	6.93e-04	24	37	2	ctd:D007531
Drug	perindoprilat	MME ACHE	6.93e-04	24	37	2	CID000072022
Drug	map J	MME ACHE	6.93e-04	24	37	2	CID000016421
Drug	leptophos	MME ACHE	7.53e-04	25	37	2	CID000030709
Drug	4-AP	ACHE KCNJ6 KCNJ10 KCNJ15	7.93e-04	258	37	4	CID000001727
Drug	p-nitrophenyl-alpha-D-glucopyranoside	ATRN KCNJ10 KCNJ15	8.82e-04	116	37	3	CID000065115
Drug	x1 00	ACHE PI4KA	9.46e-04	28	37	2	CID000019153
Drug	malaoxon	MME ACHE	9.46e-04	28	37	2	CID000015415
Drug	fenitrothion	MME ACHE	9.46e-04	28	37	2	CID000031200
Drug	triphosphoinositide	PI4KA KCNJ6 KCNJ10 KCNJ15	9.78e-04	273	37	4	CID009543520
Drug	Betamethasone	MME NR3C1	1.01e-03	29	37	2	ctd:D001623
Drug	H-8105	NR3C1 ACHE KCNJ6 KCNJ15	1.10e-03	282	37	4	CID000164531
Drug	acephate	MME ACHE	1.31e-03	33	37	2	CID000001982
Drug	anti-K	MME ACHE	1.31e-03	33	37	2	CID000005337
Drug	AC1NUOTY	MME NR3C1	1.48e-03	35	37	2	CID005486808
Drug	Trifluoperazine	NR3C1 ACHE	1.48e-03	35	37	2	ctd:D014268
Disease	chromosome 22q11.2 deletion syndrome, distal (implicated_via_orthology)	SLC25A1 PI4KA	1.30e-04	14	36	2	DOID:0060413 (implicated_via_orthology)
Disease	attention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement	PLXNA4 NBEA RNMT MED27 KCNJ6 POC1B	3.82e-04	801	36	6	EFO_0003888, EFO_0007052, MONDO_0002491
Disease	uveitis (biomarker_via_orthology)	NR3C1 KCNJ10	4.27e-04	25	36	2	DOID:13141 (biomarker_via_orthology)
Disease	blood rubidium measurement	RIF1 KCNJ6	4.62e-04	26	36	2	EFO_0021529
Disease	pulmonary sarcoidosis (is_marker_for)	NR3C1 IL18R1	7.01e-04	32	36	2	DOID:13406 (is_marker_for)
Disease	chronic rhinosinusitis	WSB2 IL18R1	7.92e-04	34	36	2	EFO_1000024
Disease	mitochondrial metabolism disease (implicated_via_orthology)	MPC1 SLC25A1	8.40e-04	35	36	2	DOID:700 (implicated_via_orthology)
Disease	Prostatic Neoplasms	MME NR3C1 ACHE SURF4 BRPF1	8.61e-04	616	36	5	C0033578
Disease	Malignant neoplasm of prostate	MME NR3C1 ACHE SURF4 BRPF1	8.61e-04	616	36	5	C0376358
Disease	monocyte count	ATRN LRRC8B SLC25A1 PI4KA PHTF1 KCNJ15 POC1B	9.42e-04	1320	36	7	EFO_0005091
Disease	smoking status measurement, carotid artery intima media thickness	RFX2 SLITRK1	1.58e-03	48	36	2	EFO_0006527, EFO_0007117

Protein segments in the cluster

Peptide	Gene	Start	Entry
KIFAQRLMRYWANFA	ACHE	501	P22303
ARWKYMTLLNLLLQT	ADTRP	41	Q96IZ2
MKIFFRYQTFRFIWL	ACSM4	1	P0C7M7
QWLLKYQSLLRMFLS	DMXL1	2121	Q9Y485
FMRFAYKVQPRNWLL	MPC1	66	Q9Y5U8
VWFLYSLLMKLFQRS	CYB5R3	16	P00387
LSYNSRFWKNLLYLM	IL18R1	506	Q13478
DMQWRYKLLLFSATF	KCNJ10	61	P78508
DLKWRFNLLIFVMVY	KCNJ6	86	P48051
TQMWTILKDSRFFRY	ATRN	541	O75882
TYNNLTLKTIMAFRW	B3GALNT1	151	O75752
KMLTNWFTFLLYKFL	PLXNA4	1436	Q9HCM2
MKWRYKLTLFAATFV	KCNJ15	61	Q99712
KYSARDLQNLMSWRF	MME	361	P08473
LQKLFRDFWLYSVLM	PI4KA	791	P42356
NWQRFYQLTKLLDSM	NR3C1	711	P04150
IKVWSMYRQRFLYSL	POC1B	126	Q8TC44
FMTWLRSYIKLFQAP	MED27	266	Q6P2C8
WMLRSSLKQYSFEAL	LRRC8B	336	Q6P9F7
LNFFVEVCRRYLWKM	HERC5	601	Q9UII4
SLFLQRKYMLTWFQR	CCDC191	776	Q8NCU4
RKYMLTWFQRSQESL	CCDC191	781	Q8NCU4
RMVRVAWLFLFSKFI	ELOVL1	106	Q9BW60
QSRIFYLRNFNNWMK	RNMT	166	O43148
KTAMWRLFVKIYFLQ	OR14I1	296	A6ND48
QFLLKWSFYSSMVIR	RFX2	611	P48378
QFLLKWSFYSSMVIR	RFX3	596	P48380
MKTLLRTWSELYRAF	RIF1	701	Q5UIP0
KWMFSEIRAVFSRRY	NBEA	2206	Q8NFP9
IAYSILWDLKFLMRN	SURF4	106	O15260
VMLLANYIFFRARWK	SERPINA12	201	Q8IW75
FMQRLHSYWTLKRQS	BRPF1	536	P55201
NNTFKNLLDLRWLYM	SLITRK1	416	Q96PX8
SLRIFVWLLLLYFMQ	PHTF1	96	Q9UMS5
KYLQILTSLMRWIAF	TMEM104	231	Q8NE00
AIRFFVMTSLRNWYR	SLC25A1	196	P53007
VFLWSMRSYTLIRKL	WSB2	221	Q9NYS7
LRISFKWMVRAFSGY	TBC1D19	441	Q8N5T2