Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	glucosamine-6-phosphate deaminase activity	GNPDA1 GNPDA2	5.46e-05	2	148	2	GO:0004342
GeneOntologyMolecularFunction	glucan 1,4-alpha-glucosidase activity	MGAM MGAM2	5.46e-05	2	148	2	GO:0004339
GeneOntologyMolecularFunction	acetyl-CoA carboxylase activity	ACACA ACACB	5.46e-05	2	148	2	GO:0003989
GeneOntologyMolecularFunction	dynein intermediate chain binding	DNAH3 DYNC2H1 DNAH2 SPTBN5	1.58e-04	37	148	4	GO:0045505
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNAH3 DYNC2H1 DNAH2	3.00e-04	18	148	3	GO:0008569
GeneOntologyMolecularFunction	calcium ion binding	SLC25A24 DSG1 FAT3 CASQ1 CASQ2 SPOCK2 ADGRV1 CRP ESYT3 EYS HMCN2 EGF LPL LRP2 PROS1	4.58e-04	749	148	15	GO:0005509
GeneOntologyMolecularFunction	alpha-1,4-glucosidase activity	MGAM MGAM2	5.38e-04	5	148	2	GO:0004558
Domain	WD40_repeat_CS	POC1A GEMIN5 DENND3 WDR11 TLE2 TLE4 PWP2 WDFY3 WDR72	5.45e-06	164	145	9	IPR019775
Domain	WD40	POC1A COPB2 GEMIN5 DENND3 WDR11 RPTOR TLE2 TLE4 PWP2 WDFY3 WDR72	5.80e-06	259	145	11	PF00400
Domain	WD40	POC1A COPB2 GEMIN5 DENND3 WDR11 RPTOR TLE2 TLE4 PWP2 WDFY3 WDR72	8.02e-06	268	145	11	SM00320
Domain	WD40_repeat	POC1A COPB2 GEMIN5 DENND3 WDR11 RPTOR TLE2 TLE4 PWP2 WDFY3 WDR72	9.23e-06	272	145	11	IPR001680
Domain	WD_REPEATS_1	POC1A COPB2 GEMIN5 DENND3 WDR11 RPTOR TLE2 TLE4 PWP2 WDFY3 WDR72	1.13e-05	278	145	11	PS00678
Domain	WD_REPEATS_2	POC1A COPB2 GEMIN5 DENND3 WDR11 RPTOR TLE2 TLE4 PWP2 WDFY3 WDR72	1.17e-05	279	145	11	PS50082
Domain	WD_REPEATS_REGION	POC1A COPB2 GEMIN5 DENND3 WDR11 RPTOR TLE2 TLE4 PWP2 WDFY3 WDR72	1.17e-05	279	145	11	PS50294
Domain	WD40/YVTN_repeat-like_dom	POC1A COPB2 GEMIN5 DENND3 WDR11 RPTOR TLE2 TLE4 PWP2 WDFY3 PLXNA2 WDR72	1.22e-05	335	145	12	IPR015943
Domain	WD40_repeat_dom	POC1A COPB2 GEMIN5 DENND3 WDR11 RPTOR TLE2 TLE4 PWP2 WDFY3 WDR72	2.09e-05	297	145	11	IPR017986
Domain	PH_dom-spectrin-type	SPTBN1 PSD3 SPTBN5	3.72e-05	9	145	3	IPR001605
Domain	-	POC1A COPB2 GEMIN5 DENND3 WDR11 RPTOR TLE2 TLE4 WDFY3 PLXNA2 WDR72	5.93e-05	333	145	11	2.130.10.10
Domain	ACC_central	ACACA ACACB	5.99e-05	2	145	2	PF08326
Domain	Calsequestrin_CS	CASQ1 CASQ2	5.99e-05	2	145	2	IPR018233
Domain	Glucosamine6P_isomerase_CS	GNPDA1 GNPDA2	5.99e-05	2	145	2	IPR018321
Domain	Calsequestrin	CASQ1 CASQ2	5.99e-05	2	145	2	PF01216
Domain	Glucosamine6P_isomerase	GNPDA1 GNPDA2	5.99e-05	2	145	2	IPR004547
Domain	GLC_GALNAC_ISOMERASE	GNPDA1 GNPDA2	5.99e-05	2	145	2	PS01161
Domain	AcCoA_COase_cen	ACACA ACACB	5.99e-05	2	145	2	IPR013537
Domain	CALSEQUESTRIN_1	CASQ1 CASQ2	5.99e-05	2	145	2	PS00863
Domain	CALSEQUESTRIN_2	CASQ1 CASQ2	5.99e-05	2	145	2	PS00864
Domain	-	FAT3 ADGRV1 CRP EYS WDFY3 PROS1	9.72e-05	95	145	6	2.60.120.200
Domain	EGF_Ca-bd_CS	FAT3 EYS HMCN2 EGF LRP2 PROS1	1.09e-04	97	145	6	IPR018097
Domain	EGF_CA	FAT3 EYS HMCN2 EGF LRP2 PROS1	1.22e-04	99	145	6	PS01187
Domain	ASX_HYDROXYL	FAT3 EYS HMCN2 EGF LRP2 PROS1	1.29e-04	100	145	6	PS00010
Domain	Dynein_heavy_chain_D4_dom	DNAH3 DYNC2H1 DNAH2	1.57e-04	14	145	3	IPR024317
Domain	Dynein_HC_stalk	DNAH3 DYNC2H1 DNAH2	1.57e-04	14	145	3	IPR024743
Domain	Dynein_heavy_dom-2	DNAH3 DYNC2H1 DNAH2	1.57e-04	14	145	3	IPR013602
Domain	DHC_N2	DNAH3 DYNC2H1 DNAH2	1.57e-04	14	145	3	PF08393
Domain	ATPase_dyneun-rel_AAA	DNAH3 DYNC2H1 DNAH2	1.57e-04	14	145	3	IPR011704
Domain	MT	DNAH3 DYNC2H1 DNAH2	1.57e-04	14	145	3	PF12777
Domain	AAA_8	DNAH3 DYNC2H1 DNAH2	1.57e-04	14	145	3	PF12780
Domain	AAA_5	DNAH3 DYNC2H1 DNAH2	1.57e-04	14	145	3	PF07728
Domain	EGF-type_Asp/Asn_hydroxyl_site	FAT3 EYS HMCN2 EGF LRP2 PROS1	1.78e-04	106	145	6	IPR000152
Domain	DHC_fam	DNAH3 DYNC2H1 DNAH2	1.95e-04	15	145	3	IPR026983
Domain	Dynein_heavy	DNAH3 DYNC2H1 DNAH2	1.95e-04	15	145	3	PF03028
Domain	Dynein_heavy_dom	DNAH3 DYNC2H1 DNAH2	1.95e-04	15	145	3	IPR004273
Domain	-	APEH EGF TENM1 LRP2	2.32e-04	39	145	4	2.120.10.30
Domain	Carboxyl_trans	ACACA ACACB	3.56e-04	4	145	2	PF01039
Domain	Gal_mutarotase_N	MGAM MGAM2	3.56e-04	4	145	2	IPR031727
Domain	COA_CT_CTER	ACACA ACACB	3.56e-04	4	145	2	PS50989
Domain	COA_CT_NTER	ACACA ACACB	3.56e-04	4	145	2	PS50980
Domain	COA_CT_N	ACACA ACACB	3.56e-04	4	145	2	IPR011762
Domain	COA_CT_C	ACACA ACACB	3.56e-04	4	145	2	IPR011763
Domain	Glc/Gal-6P_isomerase	GNPDA1 GNPDA2	3.56e-04	4	145	2	IPR006148
Domain	NtCtMGAM_N	MGAM MGAM2	3.56e-04	4	145	2	PF16863
Domain	Calsequestrin	CASQ1 CASQ2	3.56e-04	4	145	2	IPR001393
Domain	Carboxyl_trans	ACACA ACACB	3.56e-04	4	145	2	IPR000022
Domain	Glucosamine_iso	GNPDA1 GNPDA2	3.56e-04	4	145	2	PF01182
Domain	EGF_CA	FAT3 EYS HMCN2 EGF LRP2 PROS1	3.81e-04	122	145	6	SM00179
Domain	EGF-like_Ca-bd_dom	FAT3 EYS HMCN2 EGF LRP2 PROS1	4.16e-04	124	145	6	IPR001881
Domain	6-blade_b-propeller_TolB-like	APEH EGF TENM1 LRP2	4.41e-04	46	145	4	IPR011042
Domain	EGF_CA	FAT3 HMCN2 EGF LRP2 PROS1	5.53e-04	86	145	5	PF07645
Domain	Groucho_enhance	TLE2 TLE4	5.89e-04	5	145	2	IPR009146
Domain	Biotin_BS	ACACA ACACB	5.89e-04	5	145	2	IPR001882
Domain	TLE_N	TLE2 TLE4	5.89e-04	5	145	2	PF03920
Domain	Biotin_COase_C	ACACA ACACB	5.89e-04	5	145	2	IPR005482
Domain	Groucho/TLE_N	TLE2 TLE4	5.89e-04	5	145	2	IPR005617
Domain	BC	ACACA ACACB	5.89e-04	5	145	2	PS50979
Domain	Biotin_carb_C	ACACA ACACB	5.89e-04	5	145	2	SM00878
Domain	Biotin_carb_C	ACACA ACACB	5.89e-04	5	145	2	PF02785
Domain	Biotin_carboxylation_dom	ACACA ACACB	5.89e-04	5	145	2	IPR011764
Domain	CPSASE_1	ACACA ACACB	5.89e-04	5	145	2	PS00866
Domain	BIOTIN	ACACA ACACB	5.89e-04	5	145	2	PS00188
Domain	Spectrin	SPTBN1 SPTBN5 SYNE2	7.24e-04	23	145	3	PF00435
Domain	ACTININ_2	SPTBN1 SPTBN5 SYNE2	7.24e-04	23	145	3	PS00020
Domain	ACTININ_1	SPTBN1 SPTBN5 SYNE2	7.24e-04	23	145	3	PS00019
Domain	Actinin_actin-bd_CS	SPTBN1 SPTBN5 SYNE2	7.24e-04	23	145	3	IPR001589
Domain	Glyco_hydro_31_AS	MGAM MGAM2	8.80e-04	6	145	2	IPR030458
Domain	Rudment_hybrid_motif	ACACA ACACB	8.80e-04	6	145	2	IPR011054
Domain	CPSASE_2	ACACA ACACB	8.80e-04	6	145	2	PS00867
Domain	EGF_2	FAT3 EYS HMCN2 EGF TENM1 LRP2 EPHA3 PROS1	1.11e-03	265	145	8	PS01186
Domain	IPT	PKHD1L1 NFATC2 PLXNA2	1.17e-03	27	145	3	SM00429
Domain	Glyco_hydro_31	MGAM MGAM2	1.23e-03	7	145	2	IPR000322
Domain	Glyco_hydro_31	MGAM MGAM2	1.23e-03	7	145	2	PF01055
Domain	CbamoylP_synth_lsu-like_ATP-bd	ACACA ACACB	1.23e-03	7	145	2	IPR005479
Domain	BC-like_N	ACACA ACACB	1.23e-03	7	145	2	IPR005481
Domain	CPSase_L_D2	ACACA ACACB	1.23e-03	7	145	2	PF02786
Domain	Aspartic_peptidase_N	PGA4 PGA3	1.23e-03	7	145	2	IPR012848
Domain	Biotin_carb_N	ACACA ACACB	1.23e-03	7	145	2	PF00289
Domain	GLYCOSYL_HYDROL_F31_1	MGAM MGAM2	1.23e-03	7	145	2	PS00129
Domain	A1_Propeptide	PGA4 PGA3	1.23e-03	7	145	2	PF07966
Domain	Growth_fac_rcpt_	EYS HMCN2 EGF LRP2 EPHA3 PROS1	1.38e-03	156	145	6	IPR009030
Domain	Spectrin_repeat	SPTBN1 SPTBN5 SYNE2	1.44e-03	29	145	3	IPR002017
Domain	PH	CDC42BPA SH2B3 SPTBN1 PSD3 SPTBN5 SBF1 PLCL2 FERMT2	1.50e-03	278	145	8	SM00233
Domain	PH_DOMAIN	CDC42BPA SH2B3 SPTBN1 PSD3 SPTBN5 SBF1 PLCL2 FERMT2	1.53e-03	279	145	8	PS50003
Domain	PH_domain	CDC42BPA SH2B3 SPTBN1 PSD3 SPTBN5 SBF1 PLCL2 FERMT2	1.57e-03	280	145	8	IPR001849
Domain	DHC_N1	DYNC2H1 DNAH2	1.63e-03	8	145	2	PF08385
Domain	Trefoil	MGAM MGAM2	1.63e-03	8	145	2	PF00088
Domain	Dynein_heavy_dom-1	DYNC2H1 DNAH2	1.63e-03	8	145	2	IPR013594
Domain	ConA-like_dom	FAT3 ADGRV1 CRP EYS ADGRD2 WDFY3 PROS1	1.63e-03	219	145	7	IPR013320
Domain	TIG	PKHD1L1 NFATC2 PLXNA2	1.76e-03	31	145	3	PF01833
Domain	IPT	PKHD1L1 NFATC2 PLXNA2	1.93e-03	32	145	3	IPR002909
Domain	SPEC	SPTBN1 SPTBN5 SYNE2	1.93e-03	32	145	3	SM00150
Domain	Spectrin/alpha-actinin	SPTBN1 SPTBN5 SYNE2	1.93e-03	32	145	3	IPR018159
Domain	P_TREFOIL_2	MGAM MGAM2	2.08e-03	9	145	2	PS51448
Domain	PENTAXIN	CRP ADGRD2	2.08e-03	9	145	2	PS00289
Domain	Biotin_lipoyl	ACACA ACACB	2.08e-03	9	145	2	PF00364
Domain	PD	MGAM MGAM2	2.08e-03	9	145	2	SM00018
Domain	PH	CDC42BPA SH2B3 SPTBN1 PSD3 SPTBN5 SBF1 FERMT2	2.10e-03	229	145	7	PF00169
Domain	GPS	ADGRV1 PKD1 ADGRD2	2.30e-03	34	145	3	SM00303
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	ACACA COPB1 ACAT1 NSD2 DDX52 SPTBN1 COPB2 GEMIN5 PFAS PRPF40A PPM1G SBF1 SYNE2 PWP2 HECTD1	1.70e-07	653	150	15	22586326
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	SLC25A24 ACACA RBM12B DYNC2H1 NUP210L SPTBN1 COPB2 DNAH2 ABCB6 PFAS PPM1G ESYT3 CSF3 SCMH1 SYNE2	1.04e-06	754	150	15	35906200
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	TANC2 HIP1 CDC42BPA ACACA SH2B3 NSD2 RDH10 APEH GEMIN5 PFAS SBF1 RPTOR PKD1 DIP2C HMGXB3 WDFY3 HECTD1 IGSF3	1.46e-06	1105	150	18	35748872
Pubmed	Large-scale proteomics and phosphoproteomics of urinary exosomes.	GNPDA1 CDC42BPA ACAT1 DYNC2H1 SPTBN1 ABCB6 ADGRV1 BLMH ACE2 EYS EGF GUSB PKD1 LRP2 GATD1 CAPN5 LRRC15	2.04e-06	1016	150	17	19056867
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	TANC2 CDC42BPA ACACA ACACB DSG1 ACAT1 SPTBN1 COPB2 PSD3 KCNAB2 LASP1 GRIN2A PPM1G RPTOR TNRC6A TENM1 FERMT2 IGSF3	2.23e-06	1139	150	18	36417873
Pubmed	A focused and efficient genetic screening strategy in the mouse: identification of mutations that disrupt cortical development.	DYNC2H1 RDH10 LRP2	2.72e-06	7	150	3	15314648
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	ACACA COPB1 DSG1 ACAT1 DDX52 SPTBN1 DLGAP5 COPB2 GEMIN5 PFAS LASP1 BLMH GSTZ1 SBF1 WDR11 RPTOR ZBTB10 WDFY3 FERMT2	6.30e-06	1353	150	19	29467282
Pubmed	The Tumor Suppressor SASH1 Interacts With the Signal Adaptor CRKL to Inhibit Epithelial-Mesenchymal Transition and Metastasis in Colorectal Cancer.	SECISBP2L RBM12B SPTBN1 SYNE2	8.35e-06	30	150	4	30480076
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SECISBP2L TANC2 GNPDA1 DYNC2H1 PFAS DENND3 RGL1 WDR11 DIP2C KCNS2 HECTD1	1.05e-05	493	150	11	15368895
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	SLC25A24 ACACA COPB1 DSG1 ACAT1 DYNC2H1 NSD2 DDX52 SPTBN1 COPB2 GEMIN5 PFAS PRPF40A BLMH CLCA2 RPTOR PWP2 UHRF1 MGAM2	1.30e-05	1425	150	19	30948266
Pubmed	CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.	SECISBP2L ACACA COPB1 DYNC2H1 DISC1 COPB2 PFAS PPM1G HAUS8 WDR11 RPTOR GATD1	1.37e-05	606	150	12	36538041
Pubmed	Two mammalian glucosamine-6-phosphate deaminases: a structural and genetic study.	GNPDA1 GNPDA2	1.85e-05	2	150	2	12965206
Pubmed	LRRC15 mediates an accessory interaction with the SARS-CoV-2 spike protein.	ACE2 LRRC15	1.85e-05	2	150	2	36735681
Pubmed	Ouabain Regulates CFTR-Mediated Anion Secretion and Na,K-ATPase Transport in ADPKD Cells.	CFTR PKD1	1.85e-05	2	150	2	26289599
Pubmed	Cloning and functional characterization of GNPI2, a novel human homolog of glucosamine-6-phosphate isomerase/oscillin.	GNPDA1 GNPDA2	1.85e-05	2	150	2	12616532
Pubmed	Calsequestrin depolymerizes when calcium is depleted in the sarcoplasmic reticulum of working muscle.	CASQ1 CASQ2	1.85e-05	2	150	2	28069951
Pubmed	Genetic inhibition of hepatic acetyl-CoA carboxylase activity increases liver fat and alters global protein acetylation.	ACACA ACACB	1.85e-05	2	150	2	24944901
Pubmed	Mitochondrial Ca2+-handling in fast skeletal muscle fibers from wild type and calsequestrin-null mice.	CASQ1 CASQ2	1.85e-05	2	150	2	24098358
Pubmed	The chloride channel CFTR is not required for cyst growth in an ADPKD mouse model.	CFTR PKD1	1.85e-05	2	150	2	34473378
Pubmed	LRRC15 inhibits SARS-CoV-2 cellular entry in trans.	ACE2 LRRC15	1.85e-05	2	150	2	36228039
Pubmed	Hormonal regulation of acetyl-CoA carboxylase isoenzyme gene transcription.	ACACA ACACB	1.85e-05	2	150	2	20139635
Pubmed	Inhibition of Acetyl-CoA Carboxylase 1 (ACC1) and 2 (ACC2) Reduces Proliferation and De Novo Lipogenesis of EGFRvIII Human Glioblastoma Cells.	ACACA ACACB	1.85e-05	2	150	2	28081256
Pubmed	Acetyl-CoA carboxylase inhibition by ND-630 reduces hepatic steatosis, improves insulin sensitivity, and modulates dyslipidemia in rats.	ACACA ACACB	1.85e-05	2	150	2	26976583
Pubmed	Fibroblast-expressed LRRC15 is a receptor for SARS-CoV-2 spike and controls antiviral and antifibrotic transcriptional programs.	ACE2 LRRC15	1.85e-05	2	150	2	36757924
Pubmed	A gene polymorphism in acetyl-coenzyme A carboxylase beta may be associated with the C-reactive protein level in a prediabetic and diabetic population.	ACACB CRP	1.85e-05	2	150	2	21553357
Pubmed	AMPK-dependent inhibitory phosphorylation of ACC is not essential for maintaining myocardial fatty acid oxidation.	ACACA ACACB	1.85e-05	2	150	2	25001074
Pubmed	The subcellular localization of acetyl-CoA carboxylase 2.	ACACA ACACB	1.85e-05	2	150	2	10677481
Pubmed	Susceptibility of podocytes to palmitic acid is regulated by fatty acid oxidation and inversely depends on acetyl-CoA carboxylases 1 and 2.	ACACA ACACB	1.85e-05	2	150	2	24338821
Pubmed	mTORC1 hyperactivation arrests bone growth in lysosomal storage disorders by suppressing autophagy.	GUSB RPTOR	1.85e-05	2	150	2	28872463
Pubmed	The Cholesterol-Binding Sequence in Monomeric C-Reactive Protein Binds to the SARS-CoV-2 Spike Receptor-Binding Domain and Blocks Interaction With Angiotensin-Converting Enzyme 2.	CRP ACE2	1.85e-05	2	150	2	35874670
Pubmed	Calsequestrin Deletion Facilitates Hippocampal Synaptic Plasticity and Spatial Learning in Post-Natal Development.	CASQ1 CASQ2	1.85e-05	2	150	2	32751833
Pubmed	De novo fatty acid synthesis controls the fate between regulatory T and T helper 17 cells.	ACACA ACACB	1.85e-05	2	150	2	25282359
Pubmed	Acetyl-CoA carboxylase rewires cancer metabolism to allow cancer cells to survive inhibition of the Warburg effect by cetuximab.	ACACA ACACB	1.85e-05	2	150	2	27693630
Pubmed	Clinical significance and biological role of KLF17 as a tumour suppressor in colorectal cancer.	UHRF1 KLF17	1.85e-05	2	150	2	31545467
Pubmed	Glycoprotein 330, a member of the low density lipoprotein receptor family, binds lipoprotein lipase in vitro.	LPL LRP2	1.85e-05	2	150	2	7686151
Pubmed	Effects of PKB/Akt inhibitors on insulin-stimulated lipogenesis and phosphorylation state of lipogenic enzymes in white adipose tissue.	ACACA ACACB	1.85e-05	2	150	2	32215608
Pubmed	Activity and structure of human acetyl-CoA carboxylase targeted by a specific inhibitor.	ACACA ACACB	1.85e-05	2	150	2	29772612
Pubmed	Cloning of the genes encoding mouse cardiac and skeletal calsequestrins: expression pattern during embryogenesis.	CASQ1 CASQ2	1.85e-05	2	150	2	9795116
Pubmed	Phosphorylation of Acetyl-CoA Carboxylase by AMPK Reduces Renal Fibrosis and Is Essential for the Anti-Fibrotic Effect of Metformin.	ACACA ACACB	1.85e-05	2	150	2	29976587
Pubmed	Differential effect of calsequestrin ablation on structure and function of fast and slow skeletal muscle fibers.	CASQ1 CASQ2	1.85e-05	2	150	2	21941434
Pubmed	Early embryonic renal tubules of wild-type and polycystic kidney disease kidneys respond to cAMP stimulation with cystic fibrosis transmembrane conductance regulator/Na(+),K(+),2Cl(-) Co-transporter-dependent cystic dilation.	CFTR PKD1	1.85e-05	2	150	2	17108316
Pubmed	Knocking down type 2 but not type 1 calsequestrin reduces calcium sequestration and release in C2C12 skeletal muscle myotubes.	CASQ1 CASQ2	1.85e-05	2	150	2	16595676
Pubmed	Structure and regulation of acetyl-CoA carboxylase genes of metazoa.	ACACA ACACB	1.85e-05	2	150	2	15749055
Pubmed	Endogenous and maximal sarcoplasmic reticulum calcium content and calsequestrin expression in type I and type II human skeletal muscle fibres.	CASQ1 CASQ2	1.85e-05	2	150	2	24127619
Pubmed	Paradoxical buffering of calcium by calsequestrin demonstrated for the calcium store of skeletal muscle.	CASQ1 CASQ2	1.85e-05	2	150	2	20713548
Pubmed	AMPK signaling to acetyl-CoA carboxylase is required for fasting- and cold-induced appetite but not thermogenesis.	ACACA ACACB	1.85e-05	2	150	2	29433631
Pubmed	Acetyl-CoA carboxylase inhibition regulates microtubule dynamics and intracellular transport in cystic fibrosis epithelial cells.	ACACA CFTR	1.85e-05	2	150	2	30892081
Pubmed	Blocking AMPK signalling to acetyl-CoA carboxylase increases cisplatin-induced acute kidney injury and suppresses the benefit of metformin.	ACACA ACACB	1.85e-05	2	150	2	36076520
Pubmed	Inhibition of hepatic lipogenesis enhances liver tumorigenesis by increasing antioxidant defence and promoting cell survival.	ACACA ACACB	1.85e-05	2	150	2	28290443
Pubmed	Inhibition of Acetyl-CoA Carboxylase by Phosphorylation or the Inhibitor ND-654 Suppresses Lipogenesis and Hepatocellular Carcinoma.	ACACA ACACB	1.85e-05	2	150	2	30244972
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	RAB23 CACNA1F DNAH3 ACACA TOPAZ1 DISC1 COPB2 DNAH2 MAGEB6 TMEM260 PKD1 LRP2 KCNS2	1.98e-05	736	150	13	29676528
Pubmed	Nkx2.2-repressor activity is sufficient to specify alpha-cells and a small number of beta-cells in the pancreatic islet.	SLC2A2 TLE2 TLE4	2.76e-05	14	150	3	17202186
Pubmed	Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.	DNAH3 DYNC2H1 DNAH2	2.76e-05	14	150	3	9373155
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	RAB23 TDRD15 CDC42BPA ACACA ACACB COPB1 APEH PKHD1L1 PPM1G WDR11 TNRC6A FERMT2 IGSF3	3.46e-05	777	150	13	35844135
Pubmed	Transgenic mouse proteomics identifies new 14-3-3-associated proteins involved in cytoskeletal rearrangements and cell signaling.	TANC2 SPTBN1 PSD3 KCNAB2 SBF1 SMARCB1	4.46e-05	147	150	6	16959763
Pubmed	Human transcription factor protein interaction networks.	ZNF609 CDC42BPA ACACB COPB1 DDX52 SPTBN1 COPB2 LASP1 PRPF40A STAT4 PPM1G TLE4 SYNE2 TNRC6A ZBTB10 LRP2 SMARCB1 RAI2	4.70e-05	1429	150	18	35140242
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	ZNF609 CDC42BPA NSD2 SPTBN1 COPB2 PSD3 PPM1M PFAS PPM1G BLMH SBF1 WDR11 SYNE2 PLCL2 TNRC6A	5.17e-05	1049	150	15	27880917
Pubmed	AMPK activation by SC4 inhibits noradrenaline-induced lipolysis and insulin-stimulated lipogenesis in white adipose tissue.	ACACA ACACB	5.53e-05	3	150	2	34668531
Pubmed	AMPK-ACC signaling modulates platelet phospholipids and potentiates thrombus formation.	ACACA ACACB	5.53e-05	3	150	2	30018077
Pubmed	Accelerated activation of SOCE current in myotubes from two mouse models of anesthetic- and heat-induced sudden death.	CASQ1 CASQ2	5.53e-05	3	150	2	24143248
Pubmed	The epidemiology of low serum pepsinogen A levels and an international association with gastric cancer rates. EUROGAST Study Group.	PGA4 PGA3	5.53e-05	3	150	2	7926498
Pubmed	Crystal structure of human pepsinogen A.	PGA4 PGA3	5.53e-05	3	150	2	9561228
Pubmed	Role of the JP45-Calsequestrin Complex on Calcium Entry in Slow Twitch Skeletal Muscles.	CASQ1 CASQ2	5.53e-05	3	150	2	27189940
Pubmed	The combination of serum trefoil factor 3 and pepsinogen testing is a valid non-endoscopic biomarker for predicting the presence of gastric cancer: a new marker for gastric cancer risk.	PGA4 PGA3	5.53e-05	3	150	2	21455714
Pubmed	Serum pepsinogen level, atrophic gastritis and the risk of incident pancreatic cancer--a prospective cohort study.	PGA4 PGA3	5.53e-05	3	150	2	19800305
Pubmed	Serum pepsinogen reference intervals in apparently healthy Chinese population with latex enhanced turbidimetric immunoassay.	PGA4 PGA3	5.53e-05	3	150	2	24170207
Pubmed	Relationships between the human pepsinogen DNA and protein polymorphisms.	PGA4 PGA3	5.53e-05	3	150	2	3014868
Pubmed	Acetyl-coenzyme A carboxylase alpha gene variations may be associated with the direct effects of some antipsychotics on triglyceride levels.	ACACA ACACB	5.53e-05	3	150	2	19846279
Pubmed	Exploring genetic variations that may be associated with the direct effects of some antipsychotics on lipid levels.	ACACA ACACB	5.53e-05	3	150	2	18031993
Pubmed	The ratio of pepsinogen A to pepsinogen C: a sensitive test for atrophic gastritis.	PGA4 PGA3	5.53e-05	3	150	2	2799289
Pubmed	CRYSTALLINE PEPSIN : I. ISOLATION AND TESTS OF PURITY.	PGA4 PGA3	5.53e-05	3	150	2	19872561
Pubmed	Human pepsinogen A (PGA): an informative gene complex located at 11q13.	PGA4 PGA3	5.53e-05	3	150	2	1968039
Pubmed	Intronic CA-repeat and CA-rich elements: a new class of regulators of mammalian alternative splicing.	SLC2A2 GSTZ1	5.53e-05	3	150	2	15889141
Pubmed	Helicobacter pylori infection and serum pepsinogen A, pepsinogen C, and gastrin in gastritis and peptic ulcer: significance of inflammation and effect of bacterial eradication.	PGA4 PGA3	5.53e-05	3	150	2	8053437
Pubmed	Induced polymerization of mammalian acetyl-CoA carboxylase by MIG12 provides a tertiary level of regulation of fatty acid synthesis.	ACACA ACACB	5.53e-05	3	150	2	20457939
Pubmed	Family and population studies on the human pepsinogen A multigene family.	PGA4 PGA3	5.53e-05	3	150	2	2566575
Pubmed	Macrophage acetyl-CoA carboxylase regulates acute inflammation through control of glucose and lipid metabolism.	ACACA ACACB	5.53e-05	3	150	2	36417534
Pubmed	Immunoblot technique to visualise serum pepsinogen A isozymogen patterns.	PGA4 PGA3	5.53e-05	3	150	2	2229438
Pubmed	Prediction of gastric cancer development by serum pepsinogen test and Helicobacter pylori seropositivity in Eastern Asians: a systematic review and meta-analysis.	PGA4 PGA3	5.53e-05	3	150	2	25314140
Pubmed	Validation of the pepsinogen test method for gastric cancer screening using a follow-up study.	PGA4 PGA3	5.53e-05	3	150	2	19890696
Pubmed	Diagnostic value of serum pepsinogen C in patients with raised serum concentrations of pepsinogen A.	PGA4 PGA3	5.53e-05	3	150	2	8244094
Pubmed	Plasma pepsinogens, antibodies against Helicobacter pylori, and risk of gastric cancer in the Shanghai Women's Health Study Cohort.	PGA4 PGA3	5.53e-05	3	150	2	21407214
Pubmed	Isolation of an activation intermediate and determination of the amino acid sequence of the activation segment of human pepsinogen A.	PGA4 PGA3	5.53e-05	3	150	2	6774973
Pubmed	Differential activation of recombinant human acetyl-CoA carboxylases 1 and 2 by citrate.	ACACA ACACB	5.53e-05	3	150	2	18455495
Pubmed	Primary structure of human pepsinogen gene.	PGA4 PGA3	5.53e-05	3	150	2	6300126
Pubmed	Knockdown of HIP1 expression promotes ligand‑induced endocytosis of EGFR in HeLa cells.	HIP1 EGF	5.53e-05	3	150	2	29039605
Pubmed	Pepsinogen I/II ratio is related to glucose, triacylglycerol, and uric acid levels.	PGA4 PGA3	5.53e-05	3	150	2	22304859
Pubmed	Pepsinogen I and II expressions in situ and their correlations with serum pesignogen levels in gastric cancer and its precancerous disease.	PGA4 PGA3	5.53e-05	3	150	2	24004680
Pubmed	Effect of enprostil on serum gastrin and pepsinogen A and C levels in patients on long-term treatment with omeprazole.	PGA4 PGA3	5.53e-05	3	150	2	8038355
Pubmed	Human pepsinogen A isozymogen patterns in serum and gastric mucosa.	PGA4 PGA3	5.53e-05	3	150	2	2227273
Pubmed	Identification of a high risk gastric cancer group using serum pepsinogen after successful eradication of Helicobacter pylori.	PGA4 PGA3	5.53e-05	3	150	2	23034090
Pubmed	A possible association of low pepsinogen I and pepsinogen I/II with low and high body weight in Japanese men.	PGA4 PGA3	5.53e-05	3	150	2	24125879
Pubmed	Effects of omeprazole and lansoprazole on fasting and postprandial serum gastrin and serum pepsinogen A and C.	PGA4 PGA3	5.53e-05	3	150	2	8751234
Pubmed	Enzyme-linked immunosorbent assay and radioimmunoassay of serum pepsinogen A.	PGA4 PGA3	5.53e-05	3	150	2	3554488
Pubmed	Expression of serum miR-20a-5p, let-7a, and miR-320a and their correlations with pepsinogen in atrophic gastritis and gastric cancer: a case-control study.	PGA4 PGA3	5.53e-05	3	150	2	23521833
Pubmed	Close linkage of human chromosomal pepsinogen A genes.	PGA4 PGA3	5.53e-05	3	150	2	3017318
Pubmed	Serum pepsinogen test for early detection of gastric cancer in a European country.	PGA4 PGA3	5.53e-05	3	150	2	21989121
Pubmed	Serum antibodies to H+,K+-ATPase, serum pepsinogen A and Helicobacter pylori in relation to gastric mucosa morphology in patients with low or low-normal concentrations of serum cobalamins.	PGA4 PGA3	5.53e-05	3	150	2	9855083
Pubmed	Advantages of serum pepsinogen A combined with gastrin or pepsinogen C as first-line analytes in the evaluation of suspected cobalamin deficiency: a study in patients previously not subjected to gastrointestinal surgery.	PGA4 PGA3	5.53e-05	3	150	2	9797498
Pubmed	The glomerular sieving of pepsinogen A and C in man.	PGA4 PGA3	5.53e-05	3	150	2	2478370
GeneFamily	WD repeat domain containing	POC1A COPB2 GEMIN5 DENND3 WDR11 RPTOR TLE2 TLE4 PWP2 WDFY3 WDR72	2.95e-07	262	103	11	362
GeneFamily	EF-hand domain containing\|Spectrins	SPTBN1 SPTBN5	6.63e-04	7	103	2	1113
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#4_top-relative-expression-ranked_500	FAT3 SPTBN1 PNISR CRP ACE2 NALCN SYNE2 CYP7B1 WDFY3 PLXNA2 EPHA3	3.90e-08	175	147	11	gudmap_developingGonad_e14.5_ epididymis_500_k4
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_top-relative-expression-ranked_500	MGAM FAT3 SPTBN1 PNISR CRP ACE2 RGL1 NALCN SCMH1 SYNE2 CYP7B1 WDFY3 PLXNA2 EPHA3	1.13e-06	413	147	14	gudmap_developingGonad_e14.5_ epididymis_500
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_top-relative-expression-ranked_500	MGAM FAT3 SPTBN1 PNISR CRP ACE2 NALCN SCMH1 SYNE2 CYP7B1 WDFY3 PLXNA2 EPHA3	5.18e-06	406	147	13	gudmap_developingGonad_e16.5_epididymis_500
CoexpressionAtlas	DevelopingGonad_e18.5_epididymis_emap-13166_k-means-cluster#3_top-relative-expression-ranked_200	FAT3 SPTBN1 CRP NALCN EPHA3	6.20e-06	38	147	5	gudmap_developingGonad_e18.5_epididymis_200_k3
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#4_top-relative-expression-ranked_1000	FAT3 SPTBN1 PNISR CRP NALCN TNRC6A CYP7B1 WDFY3 PLXNA2 EPHA3	1.22e-05	256	147	10	gudmap_developingGonad_e14.5_ epididymis_1000_k4
CoexpressionAtlas	kidney_P1_CapMes_Crym_k-means-cluster#2_top-relative-expression-ranked_100	FAT3 CFTR SPOCK2	3.76e-05	10	147	3	gudmap_kidney_P1_CapMes_Crym_k2_100
CoexpressionAtlas	DevelopingGonad_e18.5_epididymis_emap-13166_k-means-cluster#5_top-relative-expression-ranked_1000	FAT3 SPTBN1 CASQ1 CRP NALCN TNRC6A CYP7B1 C2 EPHA3	3.79e-05	234	147	9	gudmap_developingGonad_e18.5_epididymis_1000_k5
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_top-relative-expression-ranked_1000	MGAM FAT3 SPTBN1 RDH10 GEMIN5 PNISR CRP ACE2 RGL1 NALCN SCMH1 SYNE2 TNRC6A CYP7B1 WDFY3 PLXNA2 EPHA3	4.10e-05	801	147	17	gudmap_developingGonad_e14.5_ epididymis_1000
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#1_top-relative-expression-ranked_500	FAT3 SPTBN1 CRP NALCN CYP7B1 EPHA3	4.34e-05	92	147	6	gudmap_developingGonad_e16.5_epididymis_500_k1
CoexpressionAtlas	dev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#1_top-relative-expression-ranked_1000	FAT3 PSD3 CASQ2 ZC3H12B TMEM260 ACE2 CLCA2 SYNE2 UHRF1 EPHA3	6.20e-05	310	147	10	gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k1_1000
CoexpressionAtlas	kidney_adult_RenalCapsule_k-means-cluster#1_top-relative-expression-ranked_1000	FAT3 CFTR SPOCK2 RAI2	6.82e-05	32	147	4	gudmap_kidney_adult_RenalCapsule_k1_1000
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#5_top-relative-expression-ranked_1000	DPYD FAT3 SPTBN1 CRP NALCN TNRC6A CYP7B1 EPHA3	7.06e-05	197	147	8	gudmap_developingGonad_e16.5_epididymis_1000_k5
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#1_top-relative-expression-ranked_200	FAT3 SPTBN1 CRP NALCN	8.70e-05	34	147	4	gudmap_developingGonad_e16.5_epididymis_200_k1
CoexpressionAtlas	DevelopingGonad_e18.5_epididymis_emap-13166_k-means-cluster#4_top-relative-expression-ranked_500	MGAM FAT3 SPTBN1 PNISR SYNE2 CYP7B1 WDFY3	9.25e-05	152	147	7	gudmap_developingGonad_e18.5_epididymis_500_k4
CoexpressionAtlas	DevelopingGonad_P2_epididymis_emap-30199_top-relative-expression-ranked_500	MGAM FAT3 SPTBN1 CASQ1 PNISR CRP NALCN SYNE2 C2 WDFY3 EPHA3	9.91e-05	395	147	11	gudmap_developingGonad_P2_epididymis_500
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_top-relative-expression-ranked_1000	MGAM DPYD FAT3 SPTBN1 RDH10 PNISR CRP ACE2 NALCN SCMH1 SYNE2 TNRC6A CYP7B1 WDFY3 PLXNA2 EPHA3	1.20e-04	790	147	16	gudmap_developingGonad_e16.5_epididymis_1000
CoexpressionAtlas	dev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#3_top-relative-expression-ranked_1000	SLC25A24 FAT3 PSD3 CASQ2 ZC3H12B GRIN2A ACE2 CLCA2 UHRF1 EPHA3	1.21e-04	336	147	10	gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k3_1000
CoexpressionAtlas	dev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#4_top-relative-expression-ranked_100	FAT3 CASQ2 ACE2 CLCA2	1.22e-04	37	147	4	gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k4_100
CoexpressionAtlas	DevelopingGonad_e18.5_epididymis_emap-13166_top-relative-expression-ranked_1000	MGAM FAT3 SPTBN1 CASQ1 PNISR CRP NRBP2 NALCN SCMH1 SYNE2 TNRC6A CYP7B1 C2 WDFY3 PLXNA2 EPHA3	1.37e-04	799	147	16	gudmap_developingGonad_e18.5_epididymis_1000
CoexpressionAtlas	DevelopingGonad_e12.5_ovary_emap-28876_k-means-cluster#3_top-relative-expression-ranked_1000	NSD2 SPTBN1 RDH10 PNISR ACE2 SCMH1 SYNE2 WDFY3 PLXNA2	1.38e-04	277	147	9	gudmap_developingGonad_e12.5_ovary_k3_1000
CoexpressionAtlas	DevelopingGonad_e18.5_epididymis_emap-13166_top-relative-expression-ranked_200	FAT3 SPTBN1 PNISR CRP NALCN SYNE2 EPHA3	1.60e-04	166	147	7	gudmap_developingGonad_e18.5_epididymis_200
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_top-relative-expression-ranked_200	MGAM SPTBN1 PNISR CRP ACE2 WDFY3 PLXNA2	1.66e-04	167	147	7	gudmap_developingGonad_e14.5_ epididymis_200
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_top-relative-expression-ranked_1000	TANC2 WNT2 FAT3 CFTR RDH10 LASP1 PEX5L RGL1 CLCA2 NALCN RPTOR HS3ST4 FERMT2 PLXNA2 IGSF3 EPHA3	1.79e-04	818	147	16	gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000
CoexpressionAtlas	dev gonad_e13.5_M_DevVasTestis_Flk_k-means-cluster#2_top-relative-expression-ranked_500	FAT3 CASQ2 ACE2 CLCA2	1.83e-04	41	147	4	gudmap_dev gonad_e13.5_M_gudmap_devVasTestis_Flk_k2_500
CoexpressionAtlas	DevelopingGonad_P2_epididymis_emap-30199_k-means-cluster#2_top-relative-expression-ranked_1000	DPYD FAT3 SPTBN1 CASQ1 CRP NALCN TNRC6A EPHA3	2.06e-04	230	147	8	gudmap_developingGonad_P2_epididymis_1000_k2
CoexpressionAtlas	kidney_P3_CapMes_Crym_k-means-cluster#3_top-relative-expression-ranked_500	DYNC2H1 FAT3 CFTR RDH10 SPOCK2 RAI2	2.17e-04	123	147	6	gudmap_kidney_P3_CapMes_Crym_k3_500
CoexpressionAtlas	dev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#3_top-relative-expression-ranked_200	FAT3 CASQ2 ACE2 CLCA2 EPHA3	2.64e-04	82	147	5	gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k3_200
CoexpressionAtlas	dev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_1000	SLC25A24 ACACA FAT3 DLGAP5 PSD3 CASQ2 ZC3H12B GRIN2A ACE2 CLCA2 SYNE2 UHRF1 ANKMY2 EPHA3 PROS1	3.13e-04	773	147	15	gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_1000
CoexpressionAtlas	DevelopingGonad_P2_epididymis_emap-30199_k-means-cluster#2_top-relative-expression-ranked_500	MGAM FAT3 SPTBN1 PNISR SYNE2 WDFY3	3.73e-04	136	147	6	gudmap_developingGonad_P2_epididymis_500_k2
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#1_top-relative-expression-ranked_500	MGAM ACE2 RGL1 PLXNA2	3.96e-04	50	147	4	gudmap_developingGonad_e14.5_ epididymis_500_k1
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_M-vs-F_top274_274	DSG1 RBM12B FAT3 RDH10 PNISR PRPF40A CLCA2 NALCN	4.22e-04	256	147	8	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_250_M-vs-F
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#5_top-relative-expression-ranked_200	SPTBN1 PNISR CRP WDFY3 PLXNA2	4.28e-04	91	147	5	gudmap_developingGonad_e14.5_ epididymis_200_k5
CoexpressionAtlas	DevelopingGonad_P2_epididymis_emap-30199_top-relative-expression-ranked_1000	MGAM DPYD FAT3 SPTBN1 CASQ1 PNISR CRP NRBP2 NALCN SYNE2 TNRC6A CYP7B1 C2 WDFY3 EPHA3	4.31e-04	797	147	15	gudmap_developingGonad_P2_epididymis_1000
CoexpressionAtlas	DevelopingGonad_e12.5_epididymis_emap-29139_k-means-cluster#3_top-relative-expression-ranked_1000	SPTBN1 PNISR ACE2 LPL SYNE2 TNRC6A WDFY3 IGSF3	4.56e-04	259	147	8	gudmap_developingGonad_e12.5_epididymis_k3_1000
CoexpressionAtlas	DevelopingKidney_e11.5_ureteric bud_emap-3844_k-means-cluster#4_top-relative-expression-ranked_1000	DYNC2H1 NSD2 DDX52 DLGAP5 GREB1	5.22e-04	95	147	5	gudmap_developingKidney_e11.5_ureteric bud_1000_k4
CoexpressionAtlas	DevelopingGonad_e18.5_epididymis_emap-13166_top-relative-expression-ranked_500	MGAM FAT3 SPTBN1 PNISR CRP NALCN SYNE2 CYP7B1 WDFY3 EPHA3	5.23e-04	404	147	10	gudmap_developingGonad_e18.5_epididymis_500
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_top-relative-expression-ranked_1000	TANC2 PARP11 DSG1 RBM12B FAT3 RDH10 PSD3 PNISR PRPF40A CLCA2 NALCN TENM1 RAI2 IGSF3 EPHA3	7.05e-04	836	147	15	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_1000
ToppCell	facs-Marrow-B-cells-18m-Hematologic-MPP_Fraction_B_+_C\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACACB DISC1 PSD3 ITGAX AGBL3 SBF1 PWP2 CAPN5	1.82e-07	180	150	8	7368ab31c3273374ef260f0d710d4eea83cbc4a2
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1F MGAM FAT3 CFTR ADGRV1 PKHD1L1 TENM1 LRP2	2.15e-07	184	150	8	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1F MGAM FAT3 CFTR ADGRV1 PKHD1L1 TENM1 LRP2	2.15e-07	184	150	8	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1F MGAM FAT3 CFTR ADGRV1 PKHD1L1 TENM1 LRP2	2.15e-07	184	150	8	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	TANC2 DPYD ZNF609 ACACA ADGRV1 SCMH1 DIP2C WDFY3	3.76e-07	198	150	8	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	severe-Myeloid-Neutrophils_4\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	FCRL2 MGAM HIP1 ITGAX R3HDM4 SYNE2 WDFY3 IL1RAP	3.91e-07	199	150	8	50242666def13e5d4149c563ae000d6768f086f7
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c6-FGF23\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MGAM DNAH3 DHDDS BLMH NRBP2 CSF3 IL1RAP	8.59e-07	152	150	7	0652ee3443e6fbb679d2c4f326239ae7c803f924
ToppCell	facs-Large_Intestine-Proximal-18m-Epithelial-Lgr5+_undifferentiated_cell_(Distal)\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPM2A DNAH2 PPM1M GEMIN5 CASQ2 ZC3H12B TLE2	1.81e-06	170	150	7	45de83a2231208b8e1f21061d0b91644b4a3ba93
ToppCell	390C-Lymphocytic-NK_cells-Proliferating_NK_cell\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	POC1A NSD2 NUP210L DLGAP5 HMCN2 UHRF1 DSCC1	2.56e-06	179	150	7	e67ad7ab04d0c1309296f57c1f53c5ca14c213fe
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF609 SCMH1 SYNE2 TNRC6A LRP2 DIP2C WDR72	4.06e-06	192	150	7	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	Bronchial-NucSeq\|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations	TANC2 DPYD ZNF609 ACACA ADGRV1 SCMH1 DIP2C	4.65e-06	196	150	7	ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCell	LPS_anti-TNF-Hematopoietic_Erythro-Megakary-Erythro-Mega-Erythroid\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	PGA4 DLGAP5 PKHD1L1 AK7 EYS R3HDM4 PLCL2	5.14e-06	199	150	7	565404c155dfac57c020a8f2d09cbf756da20ffd
ToppCell	LPS_anti-TNF-Hematopoietic_Erythro-Megakary\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	PGA4 DLGAP5 PKHD1L1 AK7 EYS R3HDM4 PLCL2	5.14e-06	199	150	7	6c174dbcc25b980f10a3d1dfe39e613acac73bb6
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	DPYD ZNF609 ACACA SCMH1 TNRC6A DIP2C WDFY3	5.14e-06	199	150	7	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	LPS_anti-TNF-Hematopoietic_Erythro-Megakary-Erythro-Mega\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	PGA4 DLGAP5 PKHD1L1 AK7 EYS R3HDM4 PLCL2	5.14e-06	199	150	7	284ee9632413f6404fc0b0c7c393ad813db834f2
ToppCell	Hematolymphoid-Endothelial-NOSTRIN\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	CDC42BPA SPTBN1 SPOCK2 ZC3H12B SYNE2 CYP7B1 EPHA3	5.31e-06	200	150	7	032df80aa5c40991e1c1e80f9d8da106e6aeaee2
ToppCell	Hematolymphoid-Endothelial-NOSTRIN---\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	CDC42BPA SPTBN1 SPOCK2 ZC3H12B SYNE2 CYP7B1 EPHA3	5.31e-06	200	150	7	68fce28690246895fd33354b30960ebcc31aa4cc
ToppCell	Hematolymphoid-Endothelial-NOSTRIN-\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	CDC42BPA SPTBN1 SPOCK2 ZC3H12B SYNE2 CYP7B1 EPHA3	5.31e-06	200	150	7	376b19ab5a7cd2c85f726d8ba41337d4525863e5
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW12-Mesenchymal-Unfolded_protein_responsible_cell\|GW12 / Sample Type, Dataset, Time_group, and Cell type.	ZNF609 EPM2A CFTR CD109 DNAH2 ESYT3 PLCL2	5.31e-06	200	150	7	6b7314c425f6b40f1301dd39cc02b0436e96a2ec
ToppCell	Hematolymphoid-Endothelial-NOSTRIN--\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	CDC42BPA SPTBN1 SPOCK2 ZC3H12B SYNE2 CYP7B1 EPHA3	5.31e-06	200	150	7	7fa54370221ed61bac0e09e6bcf1f3dff202a846
ToppCell	Hematolymphoid-Endothelial-NOSTRIN----L2-6\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	CDC42BPA SPTBN1 SPOCK2 ZC3H12B SYNE2 CYP7B1 EPHA3	5.31e-06	200	150	7	878bbbe32e3602723aa14ef32877ab2453b8c6e5
ToppCell	Hematolymphoid-Endothelial\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	CDC42BPA SPTBN1 SPOCK2 ZC3H12B SYNE2 CYP7B1 EPHA3	5.31e-06	200	150	7	7136936d05ab344a560cf159684c881063b5430d
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TDRD15 ACACB RDH10 LRP2 DIP2C WDR72	1.24e-05	151	150	6	f4f7156b2c0cfc78fd1841e07c9915d97ced561f
ToppCell	COVID-19-kidney-Technical/muscle_(Mes)\|kidney / Disease (COVID-19 only), tissue and cell type	DNAH3 NUP210L FAT3 EYS HS3ST4 EPHA3	1.67e-05	159	150	6	5335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCell	390C-Myeloid-Macrophage-SPP1+_Macrophage_2\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	SPOCK2 STAT4 ESYT3 NRBP2 TLE2 DSCC1	1.73e-05	160	150	6	8aaf6ac4f33ea291387fdbf9ff1a91d559391774
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	SPTBN1 SPOCK2 STAT4 TLE2 SYNE2 ZBTB10	1.85e-05	162	150	6	80317c4253bf8e897782e562f29835f181c65b98
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c5-CD16\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	TANC2 PARP11 SPTBN1 KCNAB2 RGL1	1.94e-05	97	150	5	332b4daf5106872dd891d9f9b5a891192d5d9aa8
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DNAH3 NUP210L DNAH2 EYS LRP2 HS3ST4	2.20e-05	167	150	6	3edb0570e583bb527165bcd8a4c25a042054043b
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l15\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ARHGAP40 SLC2A2 LPL C2 DSCC1 LRRC15	2.27e-05	168	150	6	a8958b94ffc3423d56c250796dd253884b46f9d9
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D231\|Adult / Lineage, Cell type, age group and donor	SECISBP2L UXS1 ACACA CFTR ADGRV1 SYNE2	2.43e-05	170	150	6	269dee5abca9f6aa079f116f0d8f1d198604d9d4
ToppCell	droplet-Marrow-BM_(NON-STC)-30m-Lymphocytic-plasma_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TANC2 DPYD ITGAX RGL1 LPL WDFY3	2.59e-05	172	150	6	7295bf3ae21a61dd6bcfa0dfb7a37d0f3e8f94ab
ToppCell	367C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	CFTR GRIN2A PEX5L PKHD1L1 LRP2 IGSF3	2.68e-05	173	150	6	e05cddf5bf63cf419343ff229453327519765be8
ToppCell	367C-Fibroblasts-Fibroblast-J_(Lipofibroblast)\|367C / Donor, Lineage, Cell class and subclass (all cells)	CFTR GRIN2A PEX5L PKHD1L1 LRP2 IGSF3	2.68e-05	173	150	6	74ad5ed33821b8816c9c8e67c50ee4496ba18e2f
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	CASQ2 SPOCK2 STAT4 NFATC2 SYNE2 TENM1	2.95e-05	176	150	6	6b1cf1e98b4509e87f9eea827fa7090ce1e504f1
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	POC1A SPTBN1 CD109 RGL1 HMCN2 NOVA2	2.95e-05	176	150	6	64e426f5e84884ce2c29acf6f4b958962a63927f
ToppCell	COVID-19-kidney-PCT-S2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SLC2A2 SULT1C2 SYNE2 TENM1 LRP2 WDR72	3.35e-05	180	150	6	358923e4228035a3e90e2957392089219e90dcd7
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD\|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	DNAH3 HIP1 FAT3 GRIN2A TNRC6A LRP2	3.45e-05	181	150	6	c80ffa2ded5975a88e9a1a7d333196f95237bf0a
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	HIP1 EPM2A ACACB ADGRV1 EGF SULT1C2	3.67e-05	183	150	6	31ab55d5f3639f5964541d5eae23044dbda3356e
ToppCell	COPD-Epithelial-ATII\|World / Disease state, Lineage and Cell class	CFTR ADGRV1 ESYT3 CSF3 LRP2 IGSF3	3.67e-05	183	150	6	8e9aab4eeec2e282c2cab9bfca6dbf40d660c7b9
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-Proliferating_Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NSD2 TOPAZ1 DLGAP5 ITGAX LPL UHRF1	3.67e-05	183	150	6	42dc31d587fbb9724b2f0be5ee8ed77233f67b86
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4\|TCGA-Pancreas / Sample_Type by Project: Shred V9	RGL1 NALCN KCNS2 CYP7B1 GREB1 EPHA3	3.79e-05	184	150	6	67164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCell	droplet-Lung-LUNG-30m-Myeloid-Proliferating_Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NSD2 DLGAP5 ITGAX LPL UHRF1 DSCC1	3.79e-05	184	150	6	16aa8e88bdd51b1d132d5cf33c29963b384a8bae
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	HIP1 EPM2A ACACB ADGRV1 EGF SULT1C2	3.90e-05	185	150	6	898a093757f86be3e18d2ef1f16a71f50ef81dc3
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HIP1 ACACB ADGRV1 EGF SULT1C2 LPL	4.14e-05	187	150	6	85e58a312fc325e4063a2d250666b99b8f99beb6
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HIP1 ACACB ADGRV1 EGF SULT1C2 LPL	4.14e-05	187	150	6	52b5b38bef3cc06487cf42c6fb22fb33f0c7ce2b
ToppCell	RV-07._Pericyte\|World / Chamber and Cluster_Paper	HIP1 CDC42BPA LASP1 DENND3 ACE2 EPHA3	4.14e-05	187	150	6	dc274d6bbda619a2c914d84e2b4069cfef1739d1
ToppCell	renal_cortex_nuclei-Adult_normal_reference\|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	MGAM ACACB PNISR EGF SYNE2 PLXNA2	4.40e-05	189	150	6	a48df46274d51e84ffb40264646de7346104efb9
ToppCell	droplet-Spleen-nan-18m-Lymphocytic-immature_NKT_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	POC1A NSD2 DLGAP5 UHRF1 DSCC1 EPHA3	4.53e-05	190	150	6	b99271d139c8d01e20feb95d99f79c9b2756b4cb
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	POC1A NSD2 FAT3 UHRF1 DSCC1 PLXNA2	4.53e-05	190	150	6	e83fa8b711aa79a1767818474f1c193b674b1c31
ToppCell	Control-Epithelial_alveolar-Mes-Like\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PARP11 CACNA1F DLGAP5 AK7 CAPN5	4.59e-05	116	150	5	df7609503782d8d7e4f31ed2a626916e5474d5bc
ToppCell	human_hepatoblastoma-Inflammatory_Monocytes\|World / Sample and Cell Type and Tumor Cluster (all cells)	TANC2 DPYD CD109 KCNAB2 ITGAX PLCL2	4.66e-05	191	150	6	3b59bfc6c106ae8a3fbcd4a74bd128c485724921
ToppCell	10x5'v1-week_12-13-Lymphocytic_B-B_lineage-pro_B_progenitor\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	UXS1 SPTBN1 PSD3 PNISR SCMH1 TLE4	4.66e-05	191	150	6	054fa0493b00149313c243d39cf39a264044f074
ToppCell	COVID-19-lung-AT2\|lung / Disease (COVID-19 only), tissue and cell type	TANC2 ACACA CFTR ADGRV1 ESYT3 LRP2	4.66e-05	191	150	6	276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SECISBP2L TANC2 ACACA CFTR ADGRV1 LRP2	4.94e-05	193	150	6	fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SECISBP2L TANC2 ACACA CFTR ADGRV1 LRP2	4.94e-05	193	150	6	f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SULT1C2 SCMH1 SYNE2 LRP2 DIP2C WDR72	5.08e-05	194	150	6	7002937e8903e037332a215d00fbc7c7843b33f2
ToppCell	3'-Adult-Appendix-Endothelial-blood_vessel_EC-Mature_venous_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HIP1 CD109 CSF3 NFATC2 NOVA2 ZNF124	5.23e-05	195	150	6	6a0460d949ccda7c9fe76870d3ee6c2f60677d61
ToppCell	(4)_B_Hypermutation\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	POC1A HTR3A DLGAP5 HAUS8 UHRF1 DSCC1	5.23e-05	195	150	6	54d2acaff6be6b5604591bdbd7d769ac3e74f223
ToppCell	facs-Trachea-3m\|Trachea / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CDC42BPA COPB1 SPTBN1 COPB2 FERMT2 PROS1	5.53e-05	197	150	6	e77016d64b1cac9825fec7cfe5071f1567401187
ToppCell	facs-Trachea-nan-3m\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDC42BPA COPB1 SPTBN1 COPB2 FERMT2 PROS1	5.53e-05	197	150	6	0353d925ee4b7aefc2c51b5fab873f465cdf9ebc
ToppCell	ASK452-Epithelial-Transformed_epithelium\|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq	CFTR PSD3 PKHD1L1 CSF3 LRP2 C2	5.53e-05	197	150	6	b22a79a5922c865a360e2afc5506a08a512fa76a
ToppCell	Fibroblasts-DKK3+_Fibroblasts\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	CDC42BPA CD109 PSD3 HMCN2 FERMT2 LRRC15	5.69e-05	198	150	6	4f4632f26a2043c5e4ab89031b4229b5dca1bd48
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar-AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SECISBP2L TANC2 ACACA CFTR ADGRV1 LRP2	5.69e-05	198	150	6	f948391296c261c473d339069a6d0f20ccd6f38f
ToppCell	10x_3'_v3-lymph_node_(10x_3'_v3)-myeloid-myeloid_macrophage\|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	CD109 ITGAX RGL1 SULT1C2 LPL C2	5.69e-05	198	150	6	c08018f099a381a66993cb60288954a6e47f105f
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar-AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SECISBP2L TANC2 ACACA CFTR ADGRV1 LRP2	5.69e-05	198	150	6	2e2a4e1756bba6f4fbe529559a97d2993c890b4b
ToppCell	Parenchymal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MGAM FAT3 CASQ2 TENM1 UHRF1 EPHA3	5.69e-05	198	150	6	d1827e3707b929e3a3562989a0c11537d344e164
ToppCell	PBMC-Control-Lymphocyte-T/NK-Other_T\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	DLGAP5 SPOCK2 STAT4 SYNE2 UHRF1 DSCC1	5.69e-05	198	150	6	80b105a7c7d00ea3b5e586831fbb755bd84f9d1a
ToppCell	10x_3'_v3-lymph_node_(10x_3'_v3)-myeloid-myeloid_macrophage-macrophage\|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	CD109 ITGAX RGL1 SULT1C2 LPL C2	5.69e-05	198	150	6	27cc7f786fb8cb230589d762a4e51b46265c1f19
ToppCell	PBMC-Control-Lymphocyte-T/NK-Other_T\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DLGAP5 SPOCK2 STAT4 SYNE2 UHRF1 DSCC1	5.69e-05	198	150	6	c73e906d2d12d6eba0e606958be16e63a2292cd0
ToppCell	Healthy_Control-Lymphoid-T\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	DLGAP5 SPOCK2 STAT4 NFATC2 SYNE2 UHRF1	5.85e-05	199	150	6	f22438fc9c02d0a4d7c936f9420b913aca851ea1
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SECISBP2L CFTR ADGRV1 ESYT3 LRP2 C2	5.85e-05	199	150	6	2dc33804f6691d7c9682e6c9b885e945fb97fc36
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW09-Neuronal-Interneuron\|GW09 / Sample Type, Dataset, Time_group, and Cell type.	WNT2 SPOCK2 ZNF778 RAI2 EPHA3 PROS1	6.02e-05	200	150	6	a6500d0d2e8bcac92381ab771dbdee66b0e1d48e
ToppCell	COVID-19-COVID-19_Severe-Lymphocyte-T/NK-dn_T\|COVID-19_Severe / Disease, condition lineage and cell class	SPTBN1 SPOCK2 PPM1G BLMH SYNE2 TENM1	6.02e-05	200	150	6	d01aa5fccada22f97d8350ad5888df2aadb5bb1c
ToppCell	severe-Myeloid-Neutrophils_4\|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	MGAM HIP1 ITGAX R3HDM4 WDFY3 IL1RAP	6.02e-05	200	150	6	b665f36dcf3c9d3981ee96f2973512f751612542
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW12-Mesenchymal\|GW12 / Sample Type, Dataset, Time_group, and Cell type.	EPM2A CFTR CD109 DNAH2 ESYT3 PLCL2	6.02e-05	200	150	6	be83f442179ba4217d12f0458059586ff3130991
ToppCell	Control-Epithelial_alveolar-Mes-Like-Differentiating_AT1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PARP11 CACNA1F DLGAP5 AK7 CAPN5	7.06e-05	127	150	5	556aaf88719c83f307fa50dfac151136ed05c8ad
ToppCell	facs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FAT3 GEMIN5 DHDDS RPTOR NOVA2	7.60e-05	129	150	5	cbeeaa554da971ba2e4c4b82c85a1d070a45abb8
ToppCell	LPS-IL1RA-Lymphocytic_NKT-iNKT/MAIT-Erythroid\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	APEH PEX5L STAT4 NALCN TENM1	8.79e-05	133	150	5	2ec3490cbf60152c3cece95eb566d749c9666517
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Diffuse-7\|TCGA-Stomach / Sample_Type by Project: Shred V9	RAB23 EPM2A CASQ1 CASQ2 KLF17	9.43e-05	135	150	5	451e90c154e26ae4f72269d6765e7ef51d67313a
ToppCell	droplet-Liver-hepatocytes-3m-Epithelial-Hepatocyte_(Pericentral_and_Periportal)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPYD SLC2A2 CRP CYP7B1 IL1RAP	1.41e-04	147	150	5	00619115b9a1ec2b967c2992043b41974ece63c4
ToppCell	10x5'-Liver-Lymphocytic_T_CD4-Tfh\|Liver / Manually curated celltypes from each tissue	RAB23 AGBL3 EPG5 TLE2 DIP2C	1.86e-04	156	150	5	85bc34ff507f9a66c6e3ba7a3ffd5416d0073ccf
ToppCell	facs-Liver-Hepatocytes\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPYD ABCB6 SLC2A2 CRP IL1RAP	1.86e-04	156	150	5	e2cda3ad4e5f44a80133864c5a38b766afb952ce
ToppCell	facs-Marrow-KLS-18m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGAX PKD1 ZBTB10 CYP7B1 RAI2	1.91e-04	157	150	5	5d08ff0ba9d3df9cc30f13cab2d2b395ea6f3446
ToppCell	facs-Marrow-KLS-18m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGAX PKD1 ZBTB10 CYP7B1 RAI2	1.91e-04	157	150	5	ad9c9b7dfeee3ae46e7e593c51a0407df12195b4
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	NUP210L SPOCK2 PEX5L NFATC2 PKD1	2.03e-04	159	150	5	b1d5ebd0c186b6d0279dab20d8f3b4a915acdc1f
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	CASQ2 SPOCK2 STAT4 NFATC2 TENM1	2.09e-04	160	150	5	8e2b51d7b42e0b6e62641efdbbc73d31561d6a3e
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT3 CFTR ADGRV1 PKHD1L1 LRP2	2.09e-04	160	150	5	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT3 CFTR ADGRV1 PKHD1L1 LRP2	2.09e-04	160	150	5	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	Adult-Mesenchymal-myofibroblast_cell-D175\|Adult / Lineage, Cell type, age group and donor	RAB23 NALCN TENM1 CAPN5 EPHA3	2.15e-04	161	150	5	048b7dc00746987a24bf870d4d278c4183eb04a2
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HTR3A RDH10 PSD3 FER1L6 ACE2	2.15e-04	161	150	5	9cfbbcd38ec2e75376bbc26001964b6991ad0e21
ToppCell	390C-Myeloid-Macrophage-SPP1+_Macrophage_2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	RAB23 ESYT3 NRBP2 TLE2 DSCC1	2.15e-04	161	150	5	2fe77af3b41e6eacb707a64feea18f9991618173
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Gpc3_Slc18a3\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	HTR3A CFTR STAT4 BCAR3 IGSF3	2.27e-04	163	150	5	ec9a20cfe0d69430f9c68cddd1ab0e4a3e4554b8
ToppCell	367C-Myeloid-Dendritic-cDC_proliferating_2\|367C / Donor, Lineage, Cell class and subclass (all cells)	MGAM POC1A DLGAP5 UHRF1 PGA3	2.34e-04	164	150	5	0662cd9d21608efacc336e0a582859f3b9a4951d
ToppCell	droplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Pericentral_and_Periportal)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACACA ACACB SLC2A2 CRP IL1RAP	2.41e-04	165	150	5	d449a568664a81d9b5538e8f409301448a32ac37
ToppCell	PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CD109 PKHD1L1 CLCA2 DSCC1 PLXNA2	2.41e-04	165	150	5	50a8513d8d2630861499393a7f102b35366bad37
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Nonclassical_Monocyte\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	TANC2 PARP11 KCNAB2 RGL1	2.43e-04	90	150	4	f1415181bad5e2cf87eedd8563c0f1d20adc4cce
ToppCell	PND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SPOCK2 PKHD1L1 SYNE2 LRP2 C2	2.54e-04	167	150	5	c042d6cdddd0e1ddef1e3ac6f4fe23151127b0f2
ToppCell	PND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SPOCK2 PKHD1L1 SYNE2 LRP2 C2	2.54e-04	167	150	5	351f8de1fbdf742ac74f9099b254d515ab539bb2
ToppCell	5'-Adult-SmallIntestine-Epithelial-Tuft-related-Tuft\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TANC2 FAT3 PEX5L TLE4 MGAM2	2.62e-04	168	150	5	8072d0496b7b730c4601009eaa69ec5366d26d73
ToppCell	PND10-Immune-Immune_Myeloid-DC-cDC2-cDC2_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	POC1A ACACA RBM12B ITGAX PLCL2	2.62e-04	168	150	5	4c402a1613fcf0a6e4d9b9d5551812940e91ff32
Drug	2,4,4'-trichlorobiphenyl	CACNA1F UXS1 CDC42BPA ACACB RBM12B NSD2 TOPAZ1 DISC1 FAT3 DLGAP5 PSD3 KCNAB2 GRIN2A PEX5L PNISR ESYT3 EGF NALCN SYNE2 ZBTB10 UHRF1 GREB1 DSCC1 PLXNA2 WDR72	2.98e-06	1411	145	25	ctd:C081766
Drug	2,4,5,2',5'-pentachlorobiphenyl	CACNA1F UXS1 CDC42BPA ACACB RBM12B NSD2 TOPAZ1 DISC1 FAT3 DLGAP5 PSD3 KCNAB2 GRIN2A PEX5L PNISR ESYT3 EGF NALCN SYNE2 ZBTB10 UHRF1 GREB1 DSCC1 PLXNA2 WDR72	4.32e-06	1441	145	25	ctd:C009828
Drug	Chlorpropamide [94-20-2]; Up 200; 14.4uM; MCF7; HT_HG-U133A	ZNF609 CDC42BPA SPTBN1 PSD3 SPOCK2 DENND3 SBF1 TLE4 NOVA2	4.78e-06	196	145	9	3210_UP
Drug	glycerol	MGAM UXS1 ACACA ACAT1 DDX52 SPTBN1 CFTR DHDDS PFAS ADGRV1 BLMH SPTBN5 GSTZ1 GUSB LPL UHRF1 C2 EPHA3	5.73e-06	829	145	18	CID000000753
Drug	potassium carbonate	MGAM GUSB C2 PLXNA2	8.68e-06	21	145	4	CID000011430
Drug	magnesium oxide	MGAM RGL1 LPL C2	1.27e-05	23	145	4	CID000014792
Drug	D-G-G	MGAM HTR3A APEH GRIN2A	1.27e-05	23	145	4	CID000444866
Drug	epirubicinol	CSF3 GUSB C2	1.38e-05	8	145	3	CID000128975
Drug	mitiglinide	MGAM CFTR GUSB LPL	2.47e-05	27	145	4	CID000121891
Drug	ICI182,780; Up 200; 1uM; PC3; HT_HG-U133A	DPYD ZNF609 ACACB SPTBN1 PNISR ZNF668 EGF PLXNA2	3.67e-05	195	145	8	6918_UP
Drug	Bretylium tosylate [61-75-6]; Up 200; 9.6uM; MCF7; HT_HG-U133A	EPM2A PDE6C ACACB DISC1 ITGAX SULT1C2 CYP7B1 PLXNA2	3.81e-05	196	145	8	3394_UP
Drug	Narea	MGAM EGF C2	4.02e-05	11	145	3	CID000016556
Drug	mebeverine-alcohol	GUSB C2	4.03e-05	2	145	2	CID000026649
Drug	D 251	GUSB LPL	4.03e-05	2	145	2	CID003048154
Drug	C 2000	CSF3 C2	4.03e-05	2	145	2	CID000054153
Drug	Scaeg	GUSB C2	4.03e-05	2	145	2	CID000063010
Drug	otavite	GUSB C2	4.03e-05	2	145	2	CID000010564
Drug	AC1L3C3S	MGAM BLMH	4.03e-05	2	145	2	CID000138114
Drug	hydroxyl radicals	MGAM DPYD UXS1 EPM2A GNPDA1 PDE6C ACAT1 PPM1M PFAS AK7 PPM1G BLMH GSTZ1 EGF GUSB LPL GNPDA2 PLCL2 LRP2 CYP7B1 C2 PROS1	4.09e-05	1341	145	22	CID000000961
Drug	Proparacaine hydrochloride [5875-06-9]; Up 200; 12uM; MCF7; HT_HG-U133A	CDC42BPA NSD2 KCNAB2 SULT1C2 LPL PLCL2 TENM1 GREB1	4.24e-05	199	145	8	6492_UP
Drug	Cefepime hydrochloride [123171-59-5]; Down 200; 7.4uM; PC3; HT_HG-U133A	TANC2 HIP1 ZNF609 KCNAB2 DENND3 ZNF668 TLE2 DIP2C	4.39e-05	200	145	8	5761_DN
Drug	6-demethylsterigmatocystin	PRPF40A GUSB C2	5.34e-05	12	145	3	CID005280620
Disease	Malignant neoplasm of breast	DPYD DYNC2H1 NSD2 CD109 ABCB6 SLC2A2 STAT4 EPG5 RGL1 ZNF668 EGF CSF3 CLCA2 SYNE2 TENM1 DIP2C BCAR3	2.24e-05	1074	145	17	C0006142
Disease	Colorectal Carcinoma	DPYD DNAH3 ACACA CFTR CD109 ABCB6 GRIN2A PEX5L TENM1 LRP2 DIP2C EPHA3 PROS1	4.57e-05	702	145	13	C0009402
Disease	C-reactive protein measurement	TDRD15 DPYD HIP1 NUP210L DDX52 PSD3 DHDDS AK7 SLC2A2 PPM1G CRP NRBP2 TLE4 LPL PKD1 EPHA3 WDR72	9.40e-05	1206	145	17	EFO_0004458
Disease	alcohol consumption measurement	SECISBP2L MGAM ACACA ACACB TOPAZ1 SPTBN1 DNAH2 DHDDS ADGRV1 PPM1G SPTBN5 NFATC2 RPTOR TNRC6A BCAR3 PLXNA2 EPHA3	1.34e-04	1242	145	17	EFO_0007878
Disease	nervous system disorder	DPYD CSF3 NFATC2 GUSB	1.36e-04	53	145	4	C0027765
Disease	triglycerides in LDL measurement	TDRD15 PSD3 LPL SYNE2	1.68e-04	56	145	4	EFO_0022320
Disease	uric acid measurement	DNAH3 CDC42BPA DYNC2H1 FAT3 ADGRV1 AK7 SLC2A2 NFATC2 LRP2 DIP2C WDR72	2.24e-04	610	145	11	EFO_0004761
Disease	muscular disease (implicated_via_orthology)	ACACA ACACB	2.38e-04	5	145	2	DOID:0080000 (implicated_via_orthology)
Disease	coronary artery disease, plasminogen activator inhibitor 1 measurement	TDRD15 SH2B3 DYNC2H1 LPL	2.66e-04	63	145	4	EFO_0001645, EFO_0004792
Disease	Autistic Disorder	DPYD HTR3A WNT2 DISC1 LASP1 GRIN2A EGF	3.20e-04	261	145	7	C0004352
Disease	lumbar disc degeneration	DYNC2H1 SPOCK2 EYS	3.48e-04	28	145	3	EFO_0004994
Disease	tissue plasminogen activator measurement, coronary artery disease	TDRD15 SH2B3 DYNC2H1 LPL	4.21e-04	71	145	4	EFO_0001645, EFO_0004791
Disease	Lupus Erythematosus, Systemic	SH2B3 STAT4 CRP C2	4.21e-04	71	145	4	C0024141
Disease	Schizophrenia	CACNA1F DPYD HTR3A DISC1 PSD3 LASP1 GRIN2A CRP WDR11 LPL PLCL2 LRP2 PLXNA2	4.33e-04	883	145	13	C0036341
Disease	gallbladder cancer (is_marker_for)	DPYD EGF	4.96e-04	7	145	2	DOID:3121 (is_marker_for)
Disease	Amphetamine-Related Disorders	PDE6C HTR3A PSD3 HS3ST4	5.19e-04	75	145	4	C0236733
Disease	Amphetamine Abuse	PDE6C HTR3A PSD3 HS3ST4	5.19e-04	75	145	4	C0236807
Disease	Amphetamine Addiction	PDE6C HTR3A PSD3 HS3ST4	5.19e-04	75	145	4	C0236804
Disease	very low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio	TDRD15 ACACB COPB1 PSD3 LPL SYNE2 NOVA2	6.12e-04	291	145	7	EFO_0008317, EFO_0020946
Disease	age at menarche	DPYD HIP1 ARHGAP40 RBM12B DNAH2 PRPF40A SCMH1 RPTOR TNRC6A GREB1	7.37e-04	594	145	10	EFO_0004703
Disease	triglyceride measurement, very low density lipoprotein cholesterol measurement	TDRD15 ACACB COPB1 PSD3 LPL SYNE2	8.66e-04	224	145	6	EFO_0004530, EFO_0008317
Disease	total cholesterol measurement, very low density lipoprotein cholesterol measurement	TDRD15 ACACB COPB1 PSD3 LPL NOVA2	8.66e-04	224	145	6	EFO_0004574, EFO_0008317
Disease	free cholesterol:total lipids ratio, intermediate density lipoprotein measurement	TDRD15 ACACB PSD3 LPL	8.69e-04	86	145	4	EFO_0008595, EFO_0020945
Disease	Liver carcinoma	DPYD ACACA DLGAP5 SLC2A2 STAT4 CRP EGF UHRF1 IL1RAP	9.38e-04	507	145	9	C2239176
Disease	fibrinogen measurement, coronary artery disease	RAB23 TDRD15 SH2B3 DYNC2H1 LPL	1.01e-03	154	145	5	EFO_0001645, EFO_0004623
Disease	Metabolic Diseases	DSG1 CRP	1.05e-03	10	145	2	C0025517
Disease	retinal vasculature measurement	CDC42BPA SH2B3 SPTBN1 PSD3 DENND3 RGL1 EYS CAPN5 WDR72	1.08e-03	517	145	9	EFO_0010554
Disease	calcium measurement	SECISBP2L SH2B3 SPTBN1 CD109 DNAH2 PSD3 GUSB TLE4 TEX101 SYNE2	1.12e-03	628	145	10	EFO_0004838
Disease	triglycerides in large LDL measurement	TDRD15 LPL SYNE2	1.24e-03	43	145	3	EFO_0022319
Disease	Semantic-Pragmatic Disorder	DPYD GRIN2A	1.28e-03	11	145	2	C0454655
Disease	1-methylxanthine measurement	PSD3 CYP7B1	1.28e-03	11	145	2	EFO_0021174
Disease	Auditory Processing Disorder, Central	DPYD GRIN2A	1.28e-03	11	145	2	C0751257
Disease	Pancreatic Ductal Adenocarcinoma	ACACB EPHA3	1.28e-03	11	145	2	C1335302
Disease	Language Delay	DPYD GRIN2A	1.28e-03	11	145	2	C0023012
Disease	Language Development Disorders	DPYD GRIN2A	1.28e-03	11	145	2	C0023014
Disease	Speech Delay	DPYD GRIN2A	1.28e-03	11	145	2	C0241210
Disease	triglyceride measurement, low density lipoprotein cholesterol measurement	TDRD15 ACACB PSD3 LPL SYNE2	1.40e-03	166	145	5	EFO_0004530, EFO_0004611
Disease	middle cerebral artery infarction (is_implicated_in)	CRP CSF3	1.53e-03	12	145	2	DOID:3525 (is_implicated_in)
Disease	end stage renal disease (biomarker_via_orthology)	ACAT1 LPL LRP2	1.61e-03	47	145	3	DOID:783 (biomarker_via_orthology)
Disease	homostachydrine measurement	EYS HS3ST4	1.81e-03	13	145	2	EFO_0021164
Disease	QRS-T angle	WNT2 SPTBN1 CASQ2 SMARCB1	1.89e-03	106	145	4	EFO_0020097
Disease	reticulocyte count	SH2B3 COPB1 GEMIN5 ABCB6 ITGAX DENND3 RGL1 EGF R3HDM4 LPL SYNE2 PKD1 ADGRD2	1.99e-03	1045	145	13	EFO_0007986
Disease	very low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio	TDRD15 SH2B3 PSD3 LPL SYNE2 NOVA2	2.00e-03	264	145	6	EFO_0008317, EFO_0020944
Disease	total cholesterol measurement, diastolic blood pressure, triglyceride measurement, systolic blood pressure, hematocrit, ventricular rate measurement, glucose measurement, body mass index, high density lipoprotein cholesterol measurement	TDRD15 PPM1G LPL	2.04e-03	51	145	3	EFO_0004340, EFO_0004348, EFO_0004468, EFO_0004530, EFO_0004574, EFO_0004612, EFO_0006335, EFO_0006336, EFO_0007928
Disease	reticulocyte measurement	SH2B3 COPB1 ACAT1 ABCB6 PFAS ITGAX DENND3 RGL1 EGF R3HDM4 LPL SYNE2 ADGRD2	2.13e-03	1053	145	13	EFO_0010700
Disease	coronary artery disease	RAB23 TDRD15 DPYD SH2B3 DYNC2H1 CFTR CD109 PSD3 EPG5 RPTOR LPL UHRF1 C2 WDR72	2.32e-03	1194	145	14	EFO_0001645
Disease	triglyceride measurement, high density lipoprotein cholesterol measurement	TDRD15 ACACB PSD3 SLC2A2 SULT1C2 LPL	2.41e-03	274	145	6	EFO_0004530, EFO_0004612
Disease	low density lipoprotein triglyceride measurement	TDRD15 LPL	2.41e-03	15	145	2	EFO_0009946
Disease	acute graft vs. host disease, donor genotype effect measurement	SLC25A24 EYS	2.41e-03	15	145	2	EFO_0004599, EFO_0007892
Disease	Hypertriglyceridemia	CRP LPL	2.41e-03	15	145	2	C0020557
Disease	Dermatitis	DSG1 EGF	2.75e-03	16	145	2	C0011603
Disease	diacylglycerol 44:7 measurement	PPM1G LPL	2.75e-03	16	145	2	EFO_0020069
Disease	health study participation	RPTOR TNRC6A UHRF1 CYP7B1 PLXNA2	2.83e-03	195	145	5	EFO_0010130
Disease	phosphatidylcholine measurement	TDRD15 PPM1G CSF3 LPL SYNE2 PGA3	2.87e-03	284	145	6	EFO_0010226
Disease	triglycerides in IDL measurement	TDRD15 PSD3 LPL	2.94e-03	58	145	3	EFO_0022149
Disease	Libman-Sacks Disease	SH2B3 STAT4 CRP	2.94e-03	58	145	3	C0242380
Disease	systemic lupus erythematosus, COVID-19	ITGAX STAT4 RGL1	2.94e-03	58	145	3	MONDO_0007915, MONDO_0100096
Disease	uterine fibroid	WNT2 CD109 DNAH2 GREB1 REV1	3.09e-03	199	145	5	EFO_0000731
Disease	low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio	TDRD15 ACACB PSD3 LPL SYNE2	3.15e-03	200	145	5	EFO_0004611, EFO_0020945
Disease	Hallux valgus	GRIN2A EYS CLCA2	3.24e-03	60	145	3	HP_0001822
Disease	very low density lipoprotein cholesterol measurement, esterified cholesterol measurement	TDRD15 LPL	3.48e-03	18	145	2	EFO_0008317, EFO_0008589
Disease	Obesity	DPYD ACACB CRP LPL GNPDA2	3.50e-03	205	145	5	C0028754
Disease	triglycerides in medium LDL measurement	TDRD15 PSD3 LPL	3.56e-03	62	145	3	EFO_0022322
Disease	triglycerides:total lipids ratio, high density lipoprotein cholesterol measurement	ACACB COPB1 PSD3 LPL SYNE2	3.58e-03	206	145	5	EFO_0004612, EFO_0020947
Disease	triglycerides:total lipids ratio, intermediate density lipoprotein measurement	PSD3 LPL SYNE2 NOVA2	3.62e-03	127	145	4	EFO_0008595, EFO_0020947
Disease	Hypertriglyceridemia	TDRD15 LPL	3.88e-03	19	145	2	EFO_0004211
Disease	Disorder of eye	CACNA1F PDE6C DHDDS ADGRV1 EYS	4.04e-03	212	145	5	C0015397
Disease	response to vaccine, cytokine measurement	DNAH3 AGBL3 TENM1 DIP2C	4.05e-03	131	145	4	EFO_0004645, EFO_0004873
Disease	non-alcoholic fatty liver disease (biomarker_via_orthology)	ACACA ACACB LPL	4.06e-03	65	145	3	DOID:0080208 (biomarker_via_orthology)
Disease	triglycerides in small LDL measurement	TDRD15 PSD3 LPL	4.06e-03	65	145	3	EFO_0022323
Disease	bitter alcoholic beverage consumption measurement	MGAM DNAH2 TNRC6A PLXNA2	4.27e-03	133	145	4	EFO_0010092
Disease	free cholesterol measurement, very low density lipoprotein cholesterol measurement	TDRD15 ACACB COPB1 PSD3 LPL	4.28e-03	215	145	5	EFO_0008317, EFO_0008591
Disease	dilated cardiomyopathy	PKD1 SMARCB1	4.30e-03	20	145	2	EFO_0000407
Disease	Mammary Carcinoma, Human	DPYD DYNC2H1 NSD2 CD109 SLC2A2 EGF CSF3 BCAR3	4.54e-03	525	145	8	C4704874
Disease	Mammary Neoplasms, Human	DPYD DYNC2H1 NSD2 CD109 SLC2A2 EGF CSF3 BCAR3	4.54e-03	525	145	8	C1257931
Disease	triglycerides in very small VLDL measurement	TDRD15 PSD3 LPL	4.61e-03	68	145	3	EFO_0022144
Disease	macrophage inflammatory protein 1b measurement	POC1A ACACA TOPAZ1 DDX52	4.62e-03	136	145	4	EFO_0008219
Disease	Mammary Neoplasms	DPYD DYNC2H1 NSD2 CD109 SLC2A2 EGF CSF3 BCAR3	4.65e-03	527	145	8	C1458155
Disease	very low density lipoprotein cholesterol measurement, lipid measurement	TDRD15 ACACB COPB1 PSD3 LPL	4.72e-03	220	145	5	EFO_0004529, EFO_0008317
Disease	Autoimmune Hepatitis	SH2B3 STAT4	4.74e-03	21	145	2	EFO_0005676
Disease	rheumatoid arthritis, ulcerative colitis	APEH STAT4	4.74e-03	21	145	2	EFO_0000685, EFO_0000729
Disease	Neutropenia	DPYD CSF3	4.74e-03	21	145	2	C0027947
Disease	total cholesterol measurement, hematocrit, stroke, ventricular rate measurement, body mass index, atrial fibrillation, high density lipoprotein cholesterol measurement, coronary artery disease, diastolic blood pressure, triglyceride measurement, systolic blood pressure, heart failure, diabetes mellitus, glucose measurement, mortality, cancer	TDRD15 PPM1G LPL	4.81e-03	69	145	3	EFO_0000275, EFO_0000400, EFO_0000712, EFO_0001645, EFO_0003144, EFO_0004340, EFO_0004348, EFO_0004352, EFO_0004468, EFO_0004530, EFO_0004574, EFO_0004612, EFO_0006335, EFO_0006336, EFO_0007928, MONDO_0004992
Disease	fasting blood insulin measurement	HIP1 COPB2 NALCN	4.81e-03	69	145	3	EFO_0004466
Disease	very low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio	TDRD15 SH2B3 PSD3 LPL SYNE2	4.90e-03	222	145	5	EFO_0008317, EFO_0020943

Protein segments in the cluster

Peptide	Gene	Start	Entry
ASVWGNFVNMRSIQE	UXS1	31	Q8NBZ7
EIASQEEGATIQWMS	DDX52	96	Q9Y2R4
GDVMTNRVVDEWFVL	ESYT3	396	A0FGR9
WTVLNMESIFEEDSQ	EPG5	1236	Q9HCE0
FVIQGDVMANSSEWV	AGBL3	886	Q8NEM8
EVVMENVTAFWEEGF	CFTR	391	P13569
AVTFEGTDMWEKNDQ	BCAR3	721	O75815
WVVTGADDMQIRVFN	COPB2	71	P35606
VKSDRSVFMNQGEWE	HTR3A	196	P46098
VTRQWAIMQEGDEFA	ADGRV1	2506	Q8WXG9
GDQNSIDIFIWEMGQ	ADGRV1	3476	Q8WXG9
MWQLQQGQEETSEDT	ABCB6	821	Q9NP58
FSWGENREEAISNMV	ACACA	561	Q13085
MQFVRTEQDETGKWN	DPYD	406	Q12882
TVQDDGEFWMTFEDV	CAPN5	316	O15484
MVMADQNQVWVGSED	DENND3	951	A2RUS2
AGWQQEFAAMDSSET	DISC1	141	Q9NRI5
GMVSIRDNNIFSEWD	GKN3P	46	P0CG01
VEVWNDFMNRSGEEQ	R3HDM4	116	Q96D70
RFIEVMQGSEQQWIE	RBM12B	221	Q8IXT5
ENGMAQLITTEAWNI	RAI2	26	Q9Y5P3
MLWDTAGQEEFDAIT	RAB23	61	Q9ULC3
QAKMSSIQDWGEEVE	RGL1	6	Q9NZL6
GSNLELNAEVMVWND	ITGAX	796	P20702
WGENREEAISNMVVA	ACACB	706	O00763
LTVFQCVTMEGWTDV	CACNA1F	321	O60840
FTEKTTDGQQIWEME	NFATC2	611	Q13469
TDGQQIWEMEATVDK	NFATC2	616	Q13469
SDEQVMVWKSNFDIV	POC1A	291	Q8NBT0
ITAVMNFQTEWDIVQ	EPM2A	186	O95278
FLAMDTEEGVEVVWN	NRBP2	56	Q9NSY0
FMNGNCATEEEVWEF	MAGEB6	296	Q8N7X4
FVDASDVTQGVDTMW	EYS	2076	Q5T1H1
IEEGVNHMWTVSAFQ	GNPDA1	216	P46926
DSCVMWNVVDVNSAG	GREB1	1646	Q4ZG55
EFDGVWIEMNEVSSL	MGAM2	471	Q2M2H8
DWGLDTMRQIQVFED	IL1RAP	26	Q9NPH3
VFDVTGSMWDELMQV	HMCN2	41	Q8NDA2
MGVEWTSCAEVVSQE	C2	631	P06681
VEFDGIWIDMNEVSN	MGAM	521	O43451
IWIDMNEVSNFVDGS	MGAM	526	O43451
GDTIVNVQQIDDGWM	LASP1	226	Q14847
DFWATMETEVIEQVA	HMGXB3	926	Q12766
GMDISNLAVDFAVVW	PLXNA2	771	O75051
VGQDVARFINWMEEE	LPL	131	P06858
AAVESDTEFWDKMQA	PEX5L	271	Q8IYB4
QVALMVANEFWEQGD	PDE6C	736	P51160
EFEWENKVTVNTNMV	COPB1	846	P53618
QWEMGIVQAEEAASM	NSD2	321	O96028
WAEEETVAAAQLITM	SLC2A2	81	P11168
MTGQSLWDVSEANVE	KCNS2	1	Q9ULS6
WAVEQLQMEAGIDQV	GNG14	16	A0A1W2PPG7
ESAWMNGEDRNILVF	LRP2	4211	P98164
ATVKAVMEQSGAWVQ	NOVA2	151	Q9UNW9
AALANQEVWEETQGM	HAUS8	326	Q9BT25
NWFEIEMNERTNVGI	DSG1	316	Q02413
TWVTFGGQITDEMAE	KCNAB2	56	Q13303
YWQITVDSITMNGEA	PGA3	251	P0DJD8
EGTVQWIVDQAAAKM	SBF1	511	O95248
AEQMFGEMEVWNAIS	PRPF40A	486	O75400
NNEVDDMDTSDTQWG	PARP11	21	Q9NR21
MEFVDVTESNARWVQ	GATD1	51	Q8NB37
ENEWDTFTGVVVGDM	DYNC2H1	3586	Q8NCM8
EQEGGMQFWVSSESK	CD109	1116	Q6YHK3
NWASAFGTQEMVEFL	HECTD1	401	Q9ULT8
WERSSFGGVQMEQVQ	IGSF3	476	O75054
AEFQEVWQQSVPEGM	DSCC1	286	Q9BVC3
AEQIAEEIGNMWRTT	DNAH3	896	Q8TD57
IWSNQQEGIITVTDM	EGF	131	P01133
VVGELIWNFADFMTE	GUSB	581	P08236
IGVVNVTDADSVWME	CASQ1	346	P31415
VRAIDMDWGANGQVT	FAT3	2836	Q8TDW7
VGDIGNVNMWDFVLS	CRP	171	P02741
LDGFWDMVSFQIEDV	DLGAP5	506	Q15398
TEEDSFQWMSRVLQA	DIP2C	851	Q9Y2E4
IDVTDAMVDQAWDAQ	ACE2	291	Q9BYF1
TWVMLEAGAETDVVN	ANKMY2	96	Q8IV38
WEMSNQDVIKAVDEG	EPHA3	826	P29320
ANDGGQWDMLVNIVE	BLMH	141	Q13867
AEQTGLQESRIQMWF	DUXB	136	A0A1W2PPF3
IEEGVNHMWTVSAFQ	GNPDA2	216	Q8TDQ7
QVGEEMQLTWAQNAI	GSTZ1	121	O43708
LDVADFATTIWQQME	CSF3	141	P09919
QAEMEQEAGELSRWQ	KLF17	6	Q5JT82
VASSVGEMWQVVDMA	LLCFC1	56	Q96L11
IGVVNVTDADSVWME	CASQ2	331	O14958
KMQGWSEVFQSRQDV	CYP7B1	256	O75881
GSVDVDVVYSQVWSM	FCRL2	466	Q96LA5
NVNWEIKMVTVEFAD	FERMT2	616	Q96AC1
EISNAVREMAWGVEQ	DHDDS	161	Q86SQ9
MLDSLNGEWVVFQQT	DNAH2	1116	Q9P225
QMTGQDFQWEQEEGD	HS3ST4	441	Q9Y661
GMMFEWSIAQDNESA	NUP210L	166	Q5VU65
VVEAGSDMVFRWTIN	PKD1	956	P98161
YWQITVDSITMNGEA	PGA4	251	P0DJD7
VKIQVWDEGSMNDVA	FER1L6	321	Q2WGJ9
WMNNVEHQTSDEDSV	SYNE2	5071	Q8WXH0
EQQSGAFDRWEMIQA	SYNE2	6526	Q8WXH0
AVESFMGNIEWSIDS	TDRD15	446	B5MCY1
IQVTDDRSVWGMTQA	LRRC15	521	Q8TF66
WEEKENVGSFTNQMT	SPATA31A6	341	Q5VVP1
WVSQMFSEIDVDNLG	PLCL2	271	Q9UPR0
DGIWNVMSSQEVVDF	PPM1G	441	O15355
WGATVMVDAADLVVQ	HIP1	881	O00291
GNISLVDQFEWDMSE	SMARCB1	271	Q12824
SIEGTLEWEDFQQRM	TANC2	731	Q9HCD6
WEQRTVVLQGFEMDA	TENM1	1116	Q9UKZ4
TNWRNMVETSDGLEA	SECISBP2L	876	Q93073
DIAMWEVNEAFSLVV	ACAT1	346	P24752
SENAVDIFDVNSMEW	CDC42BPA	1466	Q5VT25
DVINNGLWNMVSVEE	PROS1	376	P07225
WDINTQSNEETAGMV	RDH10	66	Q8IZV5
EQLTAFQVWLTMGVE	RPTOR	411	Q8N122
MASFTQAATQAEDWI	SPTBN5	2151	Q9NRC6
SSWTVEDVMQFVREA	SCMH1	591	Q96GD3
DDEEMNTWIQAISSA	SPTBN1	2291	Q01082
EVEVESDSFMNAVLW	APEH	711	P13798
EVWDVTGEVNVAMTF	ADGRD2	576	Q7Z7M1
VDNTVGNDTMFLVTW	CLCA2	516	Q9UQC9
EEEKGQNISWDMAVV	ZNF35	61	P13682
VMRAISQGVAEWTAE	WNT2	61	P09544
EEQTQAAGMVAGWLI	ZNF778	21	Q96MU6
ATQWQVVGMTVEHVE	ZNF668	471	Q96K58
FLEINQSEEASRGWM	WDFY3	111	Q8IZQ1
SEMNEWDTQNVIVTG	WDFY3	3221	Q8IZQ1
SSSMDGFWMEVEQIQ	ARHGAP40	26	Q5TG30
ETENEVKVNGMNSWN	REV1	176	Q9UBZ9
TGEWLAVGMENSNVE	TLE4	671	Q04727
GAQDSFEIFVWSMQT	PWP2	476	Q15269
QDWEAASNNETMATI	STAT4	41	Q14765
GTTWIQEIVDMIEQN	SULT1C2	51	O00338
MATDGLWDVLSNEQV	PPM1M	381	Q96MI6
AGFEVWDVTMQDLCS	PFAS	1086	O15067
AVLSQQMASWDEAVQ	GEMIN5	1211	Q8TEQ6
ETEDGMLVVNVTWRN	ZNF609	321	O15014
VSAAENGEMCVWNVT	WDR72	81	Q3MJ13
ANMFNWTTEEVETCD	TEX101	41	Q9BY14
IFEVGDEQQLNSWMA	SH2B3	286	Q9UQQ2
LWSSEAEFQGAVEEM	PKHD1L1	651	Q86WI1
QDSTEQGNADSEEWM	ZC3H12B	26	Q5HYM0
GSWEMNSVAFEDVAV	ZNF124	6	Q15973
GRQEDTILNTWMNDF	TOPAZ1	1041	Q8N9V7
VDARDTNMGAWFEAQ	UHRF1	141	Q96T88
TNMGAWFEAQVVRVT	UHRF1	146	Q96T88
WIAQREASGQQSMVE	PNISR	41	Q8TF01
MAENESEGQTKVFIW	ZBTB10	546	Q96DT7
NDGAEVWDTKEVQMV	WDR11	771	Q9BZH6
NQDWLAVGMESSNVE	TLE2	641	Q04725
MEGRSAAAETFVWVN	PSD3	1	Q9NYI0
LQSIDVDGTMTVDWN	SLC25A24	131	Q6NUK1
DVEIGMWNSNSSQEL	TNRC6A	1146	Q8NDV7
GNFMEDEQWLSSISQ	SPOCK2	36	Q92563
GVVERFWMQSNAVVA	TMEM260	351	Q9NX78
ESSQQMEEAIWAVSA	AK7	121	Q96M32
LTQEGWVDVMDQTLN	NALCN	551	Q8IZF0
VDNSFVGWDMQNVIT	GRIN2A	191	Q12879