Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionglycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity

C1GALT1 C1GALT1C1L

3.95e-053732GO:0016263
GeneOntologyMolecularFunctionchromatin binding

NCOR2 PHC3 SATB2 TCF7L2 OGT FOXN4 PATZ1 BRD4 MBD5 HCFC1

3.43e-047397310GO:0003682
GeneOntologyMolecularFunctionarmadillo repeat domain binding

STRN3 TCF7L2

4.67e-049732GO:0070016
GeneOntologyCellularComponenthistone deacetylase complex

NCOR2 SATB2 OGT ING3 TET1 KMT2E

6.08e-0785756GO:0000118
GeneOntologyCellularComponentnuclear protein-containing complex

NCOR2 PHC3 SATB2 TCF7L2 OGT ING3 GTF2A1L BCLAF1 BRD4 TET1 AHR CSTF1 POM121L2 MCM7 KMT2E CDC27 HCFC1

5.76e-0613777517GO:0140513
GeneOntologyCellularComponentnuclear chromosome

OGT ING3 BRD4 TET1 MCM7 KMT2E HCFC1

3.54e-05254757GO:0000228
GeneOntologyCellularComponentcalcium- and calmodulin-dependent protein kinase complex

CAMK2A CAMK2G

1.26e-045752GO:0005954
GeneOntologyCellularComponentchromatin

NCOR2 SATB2 TCF7L2 OGT ING3 FOXN4 BRD4 BARHL2 TET1 AHR ID2 MCM7 IPO4 KMT2E HCFC1

2.10e-0414807515GO:0000785
GeneOntologyCellularComponentH4 histone acetyltransferase complex

OGT ING3 HCFC1

5.65e-0445753GO:1902562
GeneOntologyCellularComponentNSL complex

OGT HCFC1

6.84e-0411752GO:0044545
GeneOntologyCellularComponentbasement membrane

AMELY FRAS1 HMCN1 ERBIN

9.75e-04122754GO:0005604
MousePhenoabnormal nasal bone morphology

SPRY2 SATB2 BRD4 MBD5 HCFC1

7.95e-0669565MP:0000102
MousePhenoabnormal cranium morphology

AMELY SPRY2 FRAS1 SATB2 TCF7L2 OGT FOXN4 BRD4 TET1 PFAS EPS8L3 MBD5 HCFC1

1.45e-058135613MP:0000438
MousePhenoabnormal nose morphology

SPRY2 SATB2 TCF7L2 BRD4 TET1 MBD5 HCFC1

1.46e-05201567MP:0002233
MousePhenoabnormal craniofacial bone morphology

AMELY SPRY2 FRAS1 SATB2 TCF7L2 OGT FOXN4 BRD4 TET1 PFAS EPS8L3 MBD5 HCFC1

1.74e-058275613MP:0002116
MousePhenoabnormal viscerocranium morphology

AMELY SPRY2 FRAS1 SATB2 FOXN4 BRD4 TET1 PFAS EPS8L3 MBD5 HCFC1

1.91e-055935611MP:0005274
MousePhenocomplete cleft palate

SPRY2 FRAS1

1.56e-045562MP:0021213
MousePhenoabnormal interfrontal bone morphology

TET1 PFAS

1.56e-045562MP:0008818
MousePhenoupturned snout

PFAS HCFC1

2.34e-046562MP:0006411
MousePhenoabnormal craniofacial morphology

AMELY NCOR2 SPRY2 FRAS1 SATB2 TCF7L2 OGT FOXN4 BRD4 TET1 PFAS EPS8L3 LRBA MBD5 HCFC1

2.35e-0413725615MP:0000428
MousePhenocraniofacial phenotype

AMELY NCOR2 SPRY2 FRAS1 SATB2 TCF7L2 OGT FOXN4 BRD4 TET1 PFAS EPS8L3 LRBA MBD5 HCFC1

2.35e-0413725615MP:0005382
MousePhenoabnormal maxilla morphology

SPRY2 SATB2 BRD4 PFAS EPS8L3

2.71e-04144565MP:0000455
MousePhenoabnormal spermiation

LRGUK SPEM2 AHR

2.78e-0432563MP:0004182
DomainLRRC37AB_C

LRRC37A LRRC37A3 LRRC37A2

2.48e-074753PF14914
DomainLRRC37_N

LRRC37A LRRC37A3 LRRC37A2

2.48e-074753IPR032754
DomainLRRC37AB_C

LRRC37A LRRC37A3 LRRC37A2

2.48e-074753IPR029423
DomainLRRC37

LRRC37A LRRC37A3 LRRC37A2

2.48e-074753PF15779
DomainLRRC37A/B-like

LRRC37A LRRC37A3 LRRC37A2

2.48e-074753IPR015753
DomainTCRP1

FAM168B FAM168A

1.59e-052752PF14944
DomainFAM168A/MANI

FAM168B FAM168A

1.59e-052752IPR029247
DomainCaMKII_AD

CAMK2A CAMK2G

9.50e-054752PF08332
DomainCa/CaM-dep_prot_kinase-assoc

CAMK2A CAMK2G

9.50e-054752IPR013543
PathwayKEGG_MEDICUS_REFERENCE_DEUBIQUITINATION_OF_H2AK119

PHC3 OGT MBD5 HCFC1

1.29e-0626454M47923
PathwayREACTOME_REGULATION_OF_MECP2_EXPRESSION_AND_ACTIVITY

NCOR2 CAMK2A CAMK2G

1.41e-0432453M27900
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

NCOR2 PHC3 SATB2 RAPGEF6 OGT ZNF608 MYCBP2 CAMK2G BRD4 TET1 MCM7 LRBA BIRC6

8.31e-12418771334709266
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

RAPGEF6 OGT SND1 MYCBP2 BCLAF1 BRD4 TET1 MCM7 LRBA ERBIN HCFC1

3.58e-08549771138280479
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

NCOR2 PHC3 ZNF469 USF3 TCF7L2 RAPGEF6 ING3 SPATA31E1 ITSN1 KMT2E

3.94e-08430771035044719
Pubmed

Mixed lineage leukemia 5 (MLL5) protein regulates cell cycle progression and E2F1-responsive gene expression via association with host cell factor-1 (HCF-1).

OGT KMT2E HCFC1

4.17e-08477323629655
Pubmed

Tet proteins connect the O-linked N-acetylglucosamine transferase Ogt to chromatin in embryonic stem cells.

OGT TET1 HCFC1

4.17e-08477323352454
Pubmed

Primate segmental duplication creates novel promoters for the LRRC37 gene family within the 17q21.31 inversion polymorphism region.

LRRC37A LRRC37A3 LRRC37A2

4.17e-08477322419166
Pubmed

ASXL3 bridges BRD4 to BAP1 complex and governs enhancer activity in small cell lung cancer.

OGT BRD4 HCFC1

1.24e-061077332669118
Pubmed

Evolutionary dynamism of the primate LRRC37 gene family.

LRRC37A LRRC37A3 LRRC37A2

1.24e-061077323064749
Pubmed

Transcription factor protein interactomes reveal genetic determinants in heart disease.

NCOR2 OGT ING3 BCLAF1 PATZ1 BRD4 CDC27 HCFC1

3.67e-0641177835182466
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

NCOR2 BEST1 USF3 TCF7L2 OGT FAM168A ZNF608 MYCBP2 PCDH11Y LRBA MBD5 ERBIN SH3RF3 NLK

4.38e-061489771428611215
Pubmed

Crosstalk between O-GlcNAcylation and proteolytic cleavage regulates the host cell factor-1 maturation pathway.

OGT HCFC1

4.84e-06277221285374
Pubmed

HCF-1 is cleaved in the active site of O-GlcNAc transferase.

OGT HCFC1

4.84e-06277224311690
Pubmed

A molecular model for neurodevelopmental disorders.

SATB2 MBD5

4.84e-06277225966365
Pubmed

The novel protein MANI modulates neurogenesis and neurite-cone growth.

FAM168B CDC27

4.84e-06277220716133
Pubmed

Distinct OGT-Binding Sites Promote HCF-1 Cleavage.

OGT HCFC1

4.84e-06277226305326
Pubmed

Structural variation on the short arm of the human Y chromosome: recurrent multigene deletions encompassing Amelogenin Y.

AMELY PCDH11Y

4.84e-06277217189292
Pubmed

O-GlcNAc transferase/host cell factor C1 complex regulates gluconeogenesis by modulating PGC-1α stability.

OGT HCFC1

4.84e-06277222883232
Pubmed

O-GlcNAc transferase catalyzes site-specific proteolysis of HCF-1.

OGT HCFC1

4.84e-06277221295698
Pubmed

The Biochemistry of O-GlcNAc Transferase: Which Functions Make It Essential in Mammalian Cells?

OGT HCFC1

4.84e-06277227294441
Pubmed

Hematopoietic stem cell transplantation without irradiation.

BCLAF1 KMT2E

4.84e-06277219270698
Pubmed

CaMKII is essential for the function of the enteric nervous system.

CAMK2A CAMK2G

4.84e-06277222952977
Pubmed

Retinoids repress Ah receptor CYP1A1 induction pathway through the SMRT corepressor.

NCOR2 AHR

4.84e-06277215325265
Pubmed

Ten-eleven translocation 1 (Tet1) is regulated by O-linked N-acetylglucosamine transferase (Ogt) for target gene repression in mouse embryonic stem cells.

OGT TET1

4.84e-06277223729667
Pubmed

TET1 contributes to allergic airway inflammation and regulates interferon and aryl hydrocarbon receptor signaling pathways in bronchial epithelial cells.

TET1 AHR

4.84e-06277231089182
Pubmed

Livebearing or egg-laying mammals: 27 decisive nucleotides of FAM168.

FAM168B FAM168A

4.84e-06277228381702
Pubmed

Expression of Nemo-like kinase was increased and negatively correlated with the expression of TCF4 in lung cancers.

TCF7L2 NLK

4.84e-06277226823848
Pubmed

Tumor-derived neomorphic mutations in ASXL1 impairs the BAP1-ASXL1-FOXK1/K2 transcription network.

SND1 BCLAF1 CAMK2G MCM7 HCFC1

4.98e-0611177532683582
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

NCOR2 SPRY2 FRAS1 RAPGEF6 SND1 MYCBP2 BRD4 PFAS LRBA MBD5 BIRC6 HCFC1

5.47e-061105771235748872
Pubmed

Oct4 links multiple epigenetic pathways to the pluripotency network.

NCOR2 OGT SND1 BRD4 TET1 HCFC1

6.17e-0620377622083510
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

NCOR2 STRN3 OGT MYCBP2 BCLAF1 PATZ1 CAMK2A CAMK2G ITSN1 IPO4 ERBIN

8.74e-06963771128671696
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

NCOR2 TCF7L2 ING3 ZNF608 BCLAF1 CAMK2G BRD4 SDF2L1 MCM7 KMT2E HCFC1 NLK

1.28e-051203771229180619
Pubmed

CaMKII regulates diacylglycerol lipase-α and striatal endocannabinoid signaling.

CAMK2A CAMK2G

1.45e-05377223502535
Pubmed

Zipper-interacting protein kinase (ZIPK) modulates canonical Wnt/beta-catenin signaling through interaction with Nemo-like kinase and T-cell factor 4 (NLK/TCF4).

TCF7L2 NLK

1.45e-05377221454679
Pubmed

CaMKII-δ9 promotes cardiomyopathy through disrupting UBE2T-dependent DNA repair.

CAMK2A CAMK2G

1.45e-05377231481791
Pubmed

Pluripotency transcription factors and Tet1/2 maintain Brd4-independent stem cell identity.

BRD4 TET1

1.45e-05377229662175
Pubmed

Resolvin D1 limits 5-lipoxygenase nuclear localization and leukotriene B4 synthesis by inhibiting a calcium-activated kinase pathway.

CAMK2A CAMK2G

1.45e-05377225246560
Pubmed

BRD4-binding enhancer promotes CRC progression by interacting with YY1 to activate the Wnt pathway through upregulation of TCF7L2.

TCF7L2 BRD4

1.45e-05377237879498
Pubmed

The ubiquitin specific protease 4 (USP4) is a new player in the Wnt signalling pathway.

TCF7L2 NLK

1.45e-05377220141612
Pubmed

Ca2+/calmodulin-dependent kinase II phosphorylates the epidermal growth factor receptor on multiple sites in the cytoplasmic tail and serine 744 within the kinase domain to regulate signal generation.

CAMK2A CAMK2G

1.45e-05377210347170
Pubmed

MLL5, a histone modifying enzyme, regulates androgen receptor activity in prostate cancer cells by recruiting co-regulators, HCF1 and SET1.

KMT2E HCFC1

1.45e-05377233050986
Pubmed

Analysis of Gene Expression Patterns of Epigenetic Enzymes Dnmt3a, Tet1 and Ogt in Murine Chondrogenic Models.

OGT TET1

1.45e-05377234685658
Pubmed

Effects of CaMKII-mediated phosphorylation of ryanodine receptor type 2 on islet calcium handling, insulin secretion, and glucose tolerance.

CAMK2A CAMK2G

1.45e-05377223516528
Pubmed

Intersectin 1 enhances Cbl ubiquitylation of epidermal growth factor receptor through regulation of Sprouty2-Cbl interaction.

SPRY2 ITSN1

1.45e-05377222158968
Pubmed

Pressure overload selectively up-regulates Ca2+/calmodulin-dependent protein kinase II in vivo.

CAMK2A CAMK2G

1.45e-05377212554746
Pubmed

The aryl hydrocarbon receptor activates the retinoic acid receptoralpha through SMRT antagonism.

NCOR2 AHR

1.45e-05377216480812
Pubmed

Mechanism of desensitization of the epidermal growth factor receptor protein-tyrosine kinase.

CAMK2A CAMK2G

1.45e-0537721309762
Pubmed

Receptor tyrosine kinase ubiquitylation involves the dynamic regulation of Cbl-Spry2 by intersectin 1 and the Shp2 tyrosine phosphatase.

SPRY2 ITSN1

1.45e-05377224216759
Pubmed

Calmodulin kinase II-mediated sarcoplasmic reticulum Ca2+ leak promotes atrial fibrillation in mice.

CAMK2A CAMK2G

1.45e-05377219603549
Pubmed

Calcium/calmodulin-dependent protein kinase II and calmodulin: regulators of the meiotic spindle in mouse eggs.

CAMK2A CAMK2G

1.45e-0537729882483
Pubmed

Calcium signaling through CaMKII regulates hepatic glucose production in fasting and obesity.

CAMK2A CAMK2G

2.89e-05477222503562
Pubmed

The THAP-zinc finger protein THAP1 associates with coactivator HCF-1 and O-GlcNAc transferase: a link between DYT6 and DYT3 dystonias.

OGT HCFC1

2.89e-05477220200153
Pubmed

Interactions of nuclear receptor coactivator/corepressor proteins with the aryl hydrocarbon receptor complex.

NCOR2 AHR

2.89e-05477210395741
Pubmed

Regulation of lymphoid enhancer factor 1/T-cell factor by mitogen-activated protein kinase-related Nemo-like kinase-dependent phosphorylation in Wnt/beta-catenin signaling.

TCF7L2 NLK

2.89e-05477212556497
Pubmed

Differential regulation of the ten-eleven translocation (TET) family of dioxygenases by O-linked β-N-acetylglucosamine transferase (OGT).

OGT TET1

2.89e-05477224394411
Pubmed

DUB3 Promotes BET Inhibitor Resistance and Cancer Progression by Deubiquitinating BRD4.

NCOR2 BRD4

2.89e-05477230057199
Pubmed

Developmental expression of the CaM kinase II isoforms: ubiquitous gamma- and delta-CaM kinase II are the early isoforms and most abundant in the developing nervous system.

CAMK2A CAMK2G

2.89e-05477210381553
Pubmed

TET2 and TET3 regulate GlcNAcylation and H3K4 methylation through OGT and SET1/COMPASS.

OGT HCFC1

2.89e-05477223353889
Pubmed

BAP1 promotes breast cancer cell proliferation and metastasis by deubiquitinating KLF5.

OGT HCFC1

2.89e-05477226419610
Pubmed

Phosphorylation of TET proteins is regulated via O-GlcNAcylation by the O-linked N-acetylglucosamine transferase (OGT).

OGT TET1

2.89e-05477225568311
Pubmed

Cadmium activates CaMK-II and initiates CaMK-II-dependent apoptosis in mesangial cells.

CAMK2A CAMK2G

2.89e-05477217367784
Pubmed

The silencing mediator of retinoic acid and thyroid hormone receptors can interact with the aryl hydrocarbon (Ah) receptor but fails to repress Ah receptor-dependent gene expression.

NCOR2 AHR

2.89e-05477212139968
Pubmed

[Molecular mechanisms of the intracellular localizations of Ca2+/calmodulin-dependent protein kinase II isoforms, and their physiological functions].

CAMK2A CAMK2G

2.89e-05477211889801
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

NCOR2 PHC3 SATB2 TCF7L2 ING3 ZNF608 BRD4

2.95e-0539877735016035
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

NCOR2 SATB2 TCF7L2 OGT SND1 MYCBP2 BCLAF1 CAMK2G BRD4 MCM7 HCFC1

3.06e-051103771134189442
Pubmed

Protein interactome reveals converging molecular pathways among autism disorders.

SPRY2 SND1 MYCBP2 CAMK2A CAMK2G ITSN1 CCDC92 KAZN

3.41e-0556077821653829
Pubmed

Essential roles for the splicing regulator nSR100/SRRM4 during nervous system development.

SATB2 RAPGEF6 ITSN1

4.49e-053177325838543
Pubmed

Corticothalamic Projection Neuron Development beyond Subtype Specification: Fog2 and Intersectional Controls Regulate Intraclass Neuronal Diversity.

SATB2 MYCBP2 ITSN1

4.49e-053177327321927
Pubmed

Mixed Lineage Leukemia 5 (MLL5) Protein Stability Is Cooperatively Regulated by O-GlcNac Transferase (OGT) and Ubiquitin Specific Protease 7 (USP7).

OGT KMT2E HCFC1

4.49e-053177326678539
Pubmed

Densin-180 forms a ternary complex with the (alpha)-subunit of Ca2+/calmodulin-dependent protein kinase II and (alpha)-actinin.

CAMK2A CAMK2G

4.82e-05577211160423
Pubmed

Calmodulin kinase II attenuation of gene transcription by preventing cAMP response element-binding protein (CREB) dimerization and binding of the CREB-binding protein.

CAMK2A CAMK2G

4.82e-05577211013247
Pubmed

Alpha-kinase anchoring protein alphaKAP interacts with SERCA2A to spatially position Ca2+/calmodulin-dependent protein kinase II and modulate phospholamban phosphorylation.

CAMK2A CAMK2G

4.82e-05577219671701
Pubmed

Cry2 Is Critical for Circadian Regulation of Myogenic Differentiation by Bclaf1-Mediated mRNA Stabilization of Cyclin D1 and Tmem176b.

TMEM176B BCLAF1

4.82e-05577229466738
Pubmed

Calmodulin-dependent protein kinase II potentiates transcriptional activation through activating transcription factor 1 but not cAMP response element-binding protein.

CAMK2A CAMK2G

4.82e-0557728663317
Pubmed

Ca2+/calmodulin-dependent protein kinase IIdelta and protein kinase D overexpression reinforce the histone deacetylase 5 redistribution in heart failure.

CAMK2A CAMK2G

4.82e-05577218218981
Pubmed

Aberrant calcium/calmodulin-dependent protein kinase II (CaMKII) activity is associated with abnormal dendritic spine morphology in the ATRX mutant mouse brain.

CAMK2A CAMK2G

4.82e-05577221209221
Pubmed

PTENα Modulates CaMKII Signaling and Controls Contextual Fear Memory and Spatial Learning.

CAMK2A CAMK2G

4.82e-05577228636948
Pubmed

Comparative analyses of the three-dimensional structures and enzymatic properties of alpha, beta, gamma and delta isoforms of Ca2+-calmodulin-dependent protein kinase II.

CAMK2A CAMK2G

4.82e-05577214722083
Pubmed

O-GlcNAcylation Signal Mediates Proteasome Inhibitor Resistance in Cancer Cells by Stabilizing NRF1.

OGT HCFC1

4.82e-05577229941490
Pubmed

Phosphorylation of 69-kDa choline acetyltransferase at threonine 456 in response to amyloid-beta peptide 1-42.

CAMK2A CAMK2G

4.82e-05577212486117
Pubmed

Transition from reversible to persistent binding of CaMKII to postsynaptic sites and NR2B.

CAMK2A CAMK2G

4.82e-05577216436603
Pubmed

PROSER1 mediates TET2 O-GlcNAcylation to regulate DNA demethylation on UTX-dependent enhancers and CpG islands.

OGT TET1

4.82e-05577234667079
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

NCOR2 PHC3 STRN3 RAPGEF6 MYCBP2 BCLAF1 BRD4 ITSN1 ERBIN

5.34e-0577477915302935
Pubmed

Essential roles of the histone methyltransferase ESET in the epigenetic control of neural progenitor cells during development.

SPRY2 SATB2 ID2

6.49e-053577322991445
Pubmed

The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo.

NCOR2 TCF7L2 ING3 BARHL2 PHF21B

6.80e-0519177524146773
Pubmed

NARF, an nemo-like kinase (NLK)-associated ring finger protein regulates the ubiquitylation and degradation of T cell factor/lymphoid enhancer factor (TCF/LEF).

TCF7L2 NLK

7.22e-05677216714285
Pubmed

TET1 regulates hypoxia-induced epithelial-mesenchymal transition by acting as a co-activator.

OGT TET1

7.22e-05677225517638
Pubmed

Multiple kinases regulate mafA expression in the pancreatic beta cell line MIN6.

CAMK2A CAMK2G

7.22e-05677218948074
Pubmed

Multivalent interactions of calcium/calmodulin-dependent protein kinase II with the postsynaptic density proteins NR2B, densin-180, and alpha-actinin-2.

CAMK2A CAMK2G

7.22e-05677216120608
Pubmed

Autodeubiquitination protects the tumor suppressor BAP1 from cytoplasmic sequestration mediated by the atypical ubiquitin ligase UBE2O.

OGT HCFC1

7.22e-05677224703950
Pubmed

Inactivation of smad-transforming growth factor beta signaling by Ca(2+)-calmodulin-dependent protein kinase II.

CAMK2A CAMK2G

7.22e-05677211027280
Pubmed

Requirement of Ca2+ and CaMKII for Stat1 Ser-727 phosphorylation in response to IFN-gamma.

CAMK2A CAMK2G

7.22e-05677211972023
Pubmed

Nuclear receptor corepressors Ncor1 and Ncor2 (Smrt) are required for retinoic acid-dependent repression of Fgf8 during somitogenesis.

NCOR2 SPRY2

7.22e-05677227506116
Pubmed

Defining the human deubiquitinating enzyme interaction landscape.

STRN3 OGT SND1 MYCBP2 CAMK2G CSTF1 PFAS IPO4 CDC27 HCFC1

7.38e-051005771019615732
Pubmed

C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.

OGT SND1 MYCBP2 CAMK2G CSTF1 PFAS MCM7 IPO4 CDC27 BIRC6 HCFC1

9.88e-051257771137317656
Pubmed

ERK1/2 inhibition promotes robust myotube growth via CaMKII activation resulting in myoblast-to-myotube fusion.

CAMK2A CAMK2G

1.01e-04777234932950
Pubmed

O-GlcNAc transferase associates with the MCM2-7 complex and its silencing destabilizes MCM-MCM interactions.

OGT MCM7

1.01e-04777230069701
Pubmed

Proteomic profiling of the human cytomegalovirus UL35 gene products reveals a role for UL35 in the DNA repair response.

OGT IPO4

1.01e-04777222072767
Pubmed

A role for SKIP in EBNA2 activation of CBF1-repressed promoters.

NCOR2 SND1

1.01e-04777210644367
Pubmed

Enamel-free teeth: Tbx1 deletion affects amelogenesis in rodent incisors.

AMELY SPRY2

1.01e-04777219233155
Pubmed

Rad and Rad-related GTPases interact with calmodulin and calmodulin-dependent protein kinase II.

CAMK2A CAMK2G

1.01e-0477729115241
InteractionKDM1A interactions

NCOR2 SPRY2 PHC3 SATB2 RAPGEF6 OGT ZNF608 MYCBP2 CAMK2G BRD4 TET1 ID2 MCM7 LRBA BIRC6 PHF21B

1.58e-079417216int:KDM1A
InteractionHDAC1 interactions

NCOR2 SATB2 TCF7L2 RAPGEF6 OGT ZNF608 MYCBP2 CAMK2G BRD4 TET1 MCM7 LRBA KMT2E BIRC6 HCFC1 PHF21B

1.40e-0611087216int:HDAC1
InteractionFAM168B interactions

TCF7L2 FAM168B FAM168A PATZ1 CAMK2A

2.00e-0658725int:FAM168B
InteractionEGLN3 interactions

NCOR2 SPRY2 OGT FAM168B FAM168A MYCBP2 FOXN4 BRD4 AHR SDF2L1 PFAS MCM7 IPO4 CDC27 BIRC6 ERBIN HCFC1

2.29e-0612967217int:EGLN3
InteractionTBR1 interactions

NCOR2 SATB2 TCF7L2 ZNF608 MYCBP2 BRD4

3.14e-06113726int:TBR1
InteractionPHF21A interactions

RAPGEF6 OGT MYCBP2 CAMK2G BRD4 TET1 MCM7 LRBA BIRC6

3.58e-06343729int:PHF21A
InteractionASXL1 interactions

OGT SND1 BCLAF1 CAMK2G BRD4 MCM7 MBD5 HCFC1

8.13e-06286728int:ASXL1
InteractionSIN3A interactions

NCOR2 TCF7L2 OGT BRD4 TET1 ID2 KMT2E HCFC1 PHF21B

8.18e-06380729int:SIN3A
InteractionRCOR1 interactions

NCOR2 SATB2 RAPGEF6 OGT MYCBP2 BRD4 TET1 LRBA BIRC6 PHF21B

9.83e-064947210int:RCOR1
InteractionKANSL3 interactions

OGT ZNF608 CAMK2A BRD4 HCFC1

1.41e-0586725int:KANSL3
InteractionWWTR1 interactions

RAPGEF6 OGT SND1 MYCBP2 BRD4 MCM7 LRBA ERBIN HCFC1

1.88e-05422729int:WWTR1
InteractionFOXI1 interactions

NCOR2 SATB2 TCF7L2 FAM168B ZNF608

1.95e-0592725int:FOXI1
InteractionCLEC11A interactions

TCF7L2 MYCBP2 PATZ1 AHR BIRC6

2.40e-0596725int:CLEC11A
InteractionFXR1 interactions

NCOR2 SPRY2 SND1 MYCBP2 BCLAF1 CAMK2A CAMK2G BRD4 ITSN1 CCDC92 KAZN

2.73e-056797211int:FXR1
InteractionTFCP2L1 interactions

SATB2 OGT ING3 BRD4 HCFC1

2.79e-0599725int:TFCP2L1
InteractionSAP30 interactions

NCOR2 PHC3 OGT BRD4 TET1 HCFC1

2.94e-05167726int:SAP30
InteractionCAMK2B interactions

NCOR2 STRN3 OGT MYCBP2 CAMK2A CAMK2G

4.76e-05182726int:CAMK2B
InteractionHNF1B interactions

NCOR2 SATB2 TCF7L2 ING3 ZNF608 BCLAF1

6.05e-05190726int:HNF1B
InteractionKLF5 interactions

NCOR2 TCF7L2 OGT ZNF608 BRD4 HCFC1

6.98e-05195726int:KLF5
InteractionRNF4 interactions

NCOR2 TCF7L2 ING3 ZNF608 ZNF792 BCLAF1 PATZ1 CAMK2G BRD4 SDF2L1 MCM7 KMT2E BIRC6 HCFC1 NLK

1.16e-0414127215int:RNF4
InteractionHCFC1R1 interactions

OGT HCFC1

1.25e-045722int:HCFC1R1
InteractionSRF interactions

NCOR2 PHC3 TCF7L2 OGT CAMK2A

1.40e-04139725int:SRF
InteractionTERF2IP interactions

NCOR2 PHC3 OGT TBC1D10A ZNF608 BRD4 AHR MCM7 HCFC1

1.49e-04552729int:TERF2IP
InteractionAR interactions

NCOR2 TCF7L2 OGT ZNF608 MYCBP2 PATZ1 BRD4 AHR MCM7 IPO4 CDC27 HCFC1

1.89e-049927212int:AR
InteractionSOX7 interactions

NCOR2 SATB2 TCF7L2 ZNF608

2.12e-0482724int:SOX7
InteractionRBPMS2 interactions

FAM168A MYCBP2 PATZ1 CAMK2A

2.22e-0483724int:RBPMS2
InteractionHDAC2 interactions

NCOR2 SATB2 TCF7L2 OGT MYCBP2 BRD4 TET1 MCM7 LRBA HCFC1 PHF21B

2.35e-048657211int:HDAC2
InteractionNPAS1 interactions

NCOR2 PHC3 TCF7L2 CAMK2G MCM7 LRBA

2.43e-04245726int:NPAS1
InteractionPAX2 interactions

NCOR2 SATB2 ZNF608 ID2

2.44e-0485724int:PAX2
InteractionLASP1 interactions

NCOR2 SPRY2 FAM168B FAM168A CAMK2A BRD4

2.54e-04247726int:LASP1
InteractionCAMK2N2 interactions

CAMK2A CAMK2G

2.61e-047722int:CAMK2N2
InteractionGSC interactions

NCOR2 SATB2 TCF7L2 ZNF608

2.66e-0487724int:GSC
InteractionRBPJ interactions

NCOR2 SATB2 OGT SND1 PATZ1 CDC27

2.95e-04254726int:RBPJ
CoexpressionSCHAEFFER_PROSTATE_DEVELOPMENT_6HR_DN

STRN3 FRAS1 TBC1D10A SND1 BCLAF1 BRD4 ID2 SDF2L1 CDC27

8.30e-06467769M1347
CoexpressionSCHAEFFER_PROSTATE_DEVELOPMENT_6HR_DN

STRN3 FRAS1 TBC1D10A SND1 BCLAF1 BRD4 ID2 SDF2L1 CDC27

1.10e-05484769MM999
CoexpressionZHU_CMV_8_HR_DN

TCF7L2 ITSN1 AHR ID2

1.36e-0550764M9806
CoexpressionDESCARTES_FETAL_HEART_SATB2_LRRC7_POSITIVE_CELLS

SATB2 PCDH11Y KAZN CSMD2 PHF21B

2.15e-05115765M40201
CoexpressionGSE27786_BCELL_VS_MONO_MAC_UP

STRN3 MYCBP2 BCLAF1 TET1 PFAS IPO4

2.57e-05200766M4817
CoexpressionLAKE_ADULT_KIDNEY_C16_COLLECTING_SYSTEM_PRINCIPAL_CELLS_CORTEX

FRAS1 KAZN LRBA MBD5 NLK

5.70e-05141765M39235
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF608 MYCBP2 BCLAF1 BIRC6 ERBIN

1.58e-051847651154a5ad7b8512272b7476f949ddac350910bfb7
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

PHC3 HMCN1 ZNF45 BIRC6 ERBIN

1.67e-0518676503db813598b67b1e08f759758a1c2023396921fa
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 HMCN1 NRK LRBA PHF21B

1.80e-05189765975c0f079903ae36b0ffa54e86294d42ec7697de
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 HMCN1 NRK LRBA PHF21B

1.80e-051897657eb8f5a951e80f1cfac4d7c9eb169f4eb100c917
ToppCellrenal_medulla_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

SATB2 KAZN LRBA MBD5 NLK

1.80e-05189765830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCellfacs-Marrow-KLS-3m-Hematologic-MPP_Fraction_B_+_C|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM176B SND1 PATZ1 CAMK2A MCM7

1.94e-0519276503dcd9405d3d76fc7455066ba5d83c09cd17072d
ToppCellhuman_hepatoblastoma|World / Sample and Cell Type and Tumor Cluster (all cells)

FRAS1 LRBA KMT2E MBD5 ERBIN

1.99e-05193765e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCellBronchial_Brush-Epithelial-Basal_1|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

SPRY2 FRAS1 HMCN1 TET1 ID2

2.20e-05197765f5d87824c0020c95d89e069fd9f70b49e5d5fcea
ToppCellBronchial_Brush-Epithelial-Basal_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

SPRY2 FRAS1 HMCN1 TET1 ID2

2.25e-0519876510a17d7c116dcd6cf847fe6f5d7196d887cad1f9
DrugLobeline alpha (-) hydrochoride [134-63-4]; Down 200; 10.6uM; MCF7; HT_HG-U133A

PHC3 STRN3 GLS2 CAMK2G CSTF1 PFAS CDC27

4.31e-061977672763_DN
Diseaseglucose measurement

SPRY2 METTL25B TCF7L2 LRRC37A GLS2 MYCBP2 LRRC37A3

4.36e-05380737EFO_0004468
Diseaserisky sexual behaviour measurement

LRGUK TCF7L2 SND1 BARHL2 BIRC6

6.37e-05169735EFO_0007877
Diseaserisk-taking behaviour

SPRY2 TCF7L2 GTF2A1L ZNF608 SND1 BARHL2 POM121L2 KMT2E BIRC6

1.10e-04764739EFO_0008579
Diseaseschizophrenia, type 2 diabetes mellitus

SPRY2 TCF7L2 MYCBP2

1.67e-0443733MONDO_0005090, MONDO_0005148
DiseaseR-6-hydroxywarfarin measurement

NCOR2 SPRY2 STRN3 LRBA

1.87e-04114734EFO_0803327
DiseaseSmall cell carcinoma of lung

SATB2 BCLAF1 ID2

3.29e-0454733C0149925
Diseaseaspartate aminotransferase measurement

NCOR2 RAPGEF6 SND1 OR2W5P C1GALT1 ARMC9 KAZN LRBA BIRC6

3.84e-04904739EFO_0004736
Diseasepolychlorinated biphenyls measurement

SPRY2 C1GALT1 MBD5

5.68e-0465733EFO_0007042
Diseasechenodeoxycholate measurement

TCF7L2 HMCN1

6.21e-0415732EFO_0010471
Diseaseaggressive behaviour measurement, ADHD symptom measurement

TCF7L2 CAMK2G BIRC6

6.49e-0468733EFO_0007826, EFO_0007860
Diseasediabetes mellitus

SPRY2 TCF7L2 MYCBP2

6.49e-0468733EFO_0000400
Diseaseserum alanine aminotransferase measurement, response to combination chemotherapy

AHR MCM7 CSMD2

7.36e-0471733EFO_0004735, EFO_0007965
DiseaseProstatic Neoplasms

BRD4 ITSN1 PCDH11Y AHR SDF2L1 EPS8L3 CDC27

8.27e-04616737C0033578
DiseaseMalignant neoplasm of prostate

BRD4 ITSN1 PCDH11Y AHR SDF2L1 EPS8L3 CDC27

8.27e-04616737C0376358
Diseaseurate measurement, bone density

C9orf152 FRAS1 TCF7L2 CCDC92 KAZN ERBIN SH3RF3

8.51e-04619737EFO_0003923, EFO_0004531
Diseasevital capacity

NCOR2 STRN3 BEST1 HMCN1 CAMK2G BRD4 AHR POM121L2 LRBA KMT2E

9.05e-0412367310EFO_0004312
Diseasecoffee consumption measurement

NCOR2 SND1 AHR BIRC6

1.09e-03182734EFO_0006781
Diseasecorneal hysteresis

ZNF469 TCF7L2

1.11e-0320732EFO_0010066
Diseasereaction time measurement

SATB2 SND1 BRD4 TET1 LRRC37A2 CCDC92 CDC27

1.21e-03658737EFO_0008393
DiseaseAbnormality of refraction

TCF7L2 FAM168A ZNF608 BARHL2 AHR C1GALT1 BIRC6

1.38e-03673737HP_0000539
Diseasechronic obstructive pulmonary disease

FRAS1 TCF7L2 HMCN1 CAMK2G LRRC37A2 POM121L2 C1GALT1

1.56e-03688737EFO_0000341
DiseaseCoronary heart disease

TCF7L2 CCDC92

1.61e-0324732C0010068
Diseasesocial interaction measurement

TCF7L2 BARHL2 MBD5

1.66e-0394733EFO_0009592
Diseasecortical thickness

STRN3 ZNF469 SATB2 TCF7L2 GLS2 SND1 MYCBP2 C1GALT1 SH3RF3

1.67e-031113739EFO_0004840
Diseasecortical surface area measurement

SPRY2 STRN3 ZNF469 SATB2 TCF7L2 GLS2 FAM168A SND1 MYCBP2 SH3RF3

1.70e-0313457310EFO_0010736
Diseasecerebral amyloid deposition measurement

ITSN1 KAZN PHF21B

1.71e-0395733EFO_0007707
DiseaseHyperplasia

TCF7L2 BRD4

2.19e-0328732C0020507
Diseasetype 2 diabetes mellitus (implicated_via_orthology)

TCF7L2 OGT SDF2L1

2.27e-03105733DOID:9352 (implicated_via_orthology)
Diseaseatrial fibrillation

NCOR2 SDF2L1 CCDC92 MBD5 CDC27

2.28e-03371735EFO_0000275

Protein segments in the cluster

PeptideGeneStartEntry
TQTTTHLQPLHHPSE

AHR

821

P35869
SQIHHPPQASVARHP

ERBIN

1271

Q96RT1
THTLQSHHHIPVVPA

AMELY

91

Q99218
SHHHIPVVPAQQPRV

AMELY

96

Q99218
HHSPRVPNSSVNQTE

BIRC6

4256

Q9NR09
VPHHCRQPETPTHAN

CSMD2

3186

Q7Z408
PQPAKPQQVIQHHHS

BRD4

1031

O60885
LQSHDHHPPRANSRT

BEST1

396

O76090
LVQTSPQDTSHQVHH

C9orf152

126

Q5JTZ5
QQQHHHLPTEALAPA

HCFC1

1706

P51610
HSHAHQHSPISPRTQ

NCOR2

1851

Q9Y618
AQPPEHSHLTQATVQ

LRRC37A3

531

O60309
PHPDQVQTQHSHLTR

LRRC37A3

646

O60309
HPNRIHISVQIPHQD

FRAS1

3331

Q86XX4
IRQSQQTLYHSHPPH

KAZN

286

Q674X7
QPHVIHHTTVVQPNS

FAM168A

161

Q92567
AQPPEHSHLTQATVQ

LRRC37A2

531

A6NM11
PHPDQVQTQHSHLTR

LRRC37A2

646

A6NM11
AQPPEHSHLTQATVQ

LRRC37A

531

A6NMS7
PHPDQVQTQHSHLTR

LRRC37A

646

A6NMS7
PDPQHHSTLEQHPTA

GMIP

806

Q9P107
VEDQHTPPQTAQHAR

ARMC9

666

Q7Z3E5
HISEHPNQQPSHKIQ

KIAA1109

4481

Q2LD37
QRTVPQPVQSSHCHH

C9orf131

851

Q5VYM1
LDTPSQPVNNHHAHS

ING3

126

Q9NXR8
QPVNNHHAHSHTPVE

ING3

131

Q9NXR8
RHSQHQPPHLHFEEQ

OR2W5P

281

A6NFC9
TSHFPQEKTHNHDPQ

EPS8L3

421

Q8TE67
PSQNPTIHHQTAAAV

KMT2E

1611

Q8IZD2
APQPHRHVLEISRQH

LRBA

1266

P50851
QGRETPHSHQPQHQD

GLS2

46

Q9UI32
PHSHQPQHQDHDSSE

GLS2

51

Q9UI32
HQHRQHSVPVISRPG

LRGUK

796

Q96M69
PQVVQTSPRHSPHHV

METTL25B

211

Q96FB5
HQHSHHPQQQLDIEP

NLK

126

Q9UBE8
QPHSLIKHQQIPLHS

PHC3

301

Q8NDX5
HLQDAPNATSLHVPH

GPR75

6

O95800
HITYVHQHSRQPPSQ

MCM7

536

P33993
ETQQHIQLHVHEPPS

HMCN1

1906

Q96RW7
THHGVPLPQVSRHQE

PATZ1

516

Q9HBE1
VAHRIHHATPPQAQP

CCDC92

291

Q53HC0
RHLAARPPTQAQHQH

GGT6

436

Q6P531
NTPSQHSHSIQHSPE

BCLAF1

256

Q9NYF8
NILENTPENHPDHSH

ITSN1

1391

Q15811
QTQDHEHHHLRPPNR

C1GALT1C1L

36

P0DN25
SPHHTPKQESNAVHE

BARHL2

166

Q9NY43
HIHSSPCHERPNNVS

MBD5

1221

Q9P267
DTQPNVLHNDPHARH

C1GALT1

36

Q9NS00
HNNIVRCIVHSPTNP

CSTF1

396

Q05048
TQVPNHSLSHRQPET

CDC27

186

P30260
QLLQHSTHSPHSPER

IPO4

121

Q8TEX9
NSKPIHTTILNPHVH

CAMK2G

486

Q13555
TIHNNHSVNIPVHQE

MAP3K19

511

Q56UN5
APPHVIHHTTVVQPN

FAM168B

111

A1KXE4
QLEKNRLPSVHPHHS

OGT

496

O15294
QHHSPPVTQTIVLCH

PCDH11Y

1176

Q9BZA8
ERSPSVPNNQDHAHH

NRK

786

Q7Z2Y5
LQSVPLHHQVQPQAH

FOXN4

356

Q96NZ1
LHHQVQPQAHLAPDS

FOXN4

361

Q96NZ1
NNHINRVVSHPTLPV

STRN3

681

Q13033
HLHQPHRVSQVLQVP

RAPGEF6

1171

Q8TEU7
SHPTIVSLHHQRPGQ

ID2

81

Q02363
SPHSQIHHSTPIRNQ

SATB2

271

Q9UPW6
ENPRHFVDSHHQKPV

SND1

181

Q7KZF4
QTPPESHFQRKISHH

SPATA31E1

1256

Q6ZUB1
NRAPSPHVVQENLHS

MYCBP2

2916

O75592
NSKPVHTTILNPHIH

CAMK2A

406

Q9UQM7
IQAQPQHQDSHHITI

REELD1

41

A0A1B0GV85
PPQPLHQVHRVQFVH

POM121L2

31

Q96KW2
RPSQPTHVNVHIHQE

TMEM176B

16

Q3YBM2
PEHRQPPRLQHSQVH

SPRY2

86

O43597
ELHATTPVEHPNRNH

TET1

2026

Q8NFU7
SVAATHPTVQHPQGH

PHF21B

516

Q96EK2
IPHSHSVFRNPHRSQ

SPEM2

151

Q0P670
HTHHFPSPLSNNQEV

SDF2L1

116

Q9HCN8
TSPHGALHQHVTDIQ

GTF2A1L

281

Q9UNN4
SLRPHSVVSPQHSHQ

SH3RF3

641

Q8TEJ3
HDRMTEQHFPHPIQS

PFAS

146

O15067
AHIVSNKVPVVQHPH

TCF7L2

181

Q9NQB0
PHAESSVHSQPHNVH

USF3

1496

Q68DE3
SVHSQPHNVHQQRTL

USF3

1501

Q68DE3
HSQQLHPPSPTEHEV

ZNF469

2541

Q96JG9
PQHQSVITQRHPALA

ZNF608

1061

Q9ULD9
HLAEHQTTHPRQKPF

ZNF792

146

Q3KQV3
HHPESTPHQSKETQP

TXLNB

511

Q8N3L3
PQDLAPQVSAHHRSQ

TBC1D10A

481

Q9BXI6
QRSHLPHHQRVPTGE

ZNF45

231

Q02386
CHQHPPSHLTEVLQS

nan

91

Q8TCH9